Search results for cg27243685
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sayols-Baixeras S | 28173150 | Serum triglycerides | DNA methylation | Whole blood | Discovery and replication | 3187 | cg27243685 | chr21:43642366 | ABCG1 | 0.047 | 0E+00 |
| Sayols-Baixeras S | 28173150 | Serum triglycerides | DNA methylation | Whole blood | Discovery and replication adjusted for surrogate variables | 3187 | cg27243685 | chr21:43642366 | ABCG1 | 0.064 | 0E+00 |
| Sayols-Baixeras S | 28173150 | Serum high-density lipoprotein cholesterol | DNA methylation | Whole blood | Discovery and replication | 3187 | cg27243685 | chr21:43642366 | ABCG1 | -2.564 | 0E+00 |
| Sayols-Baixeras S | 28173150 | Serum high-density lipoprotein cholesterol | DNA methylation | Whole blood | Discovery and replication adjusted for surrogate variables | 3187 | cg27243685 | chr21:43642366 | ABCG1 | -3.798 | 0E+00 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg27243685 | chr21:43642366 | ABCG1 | -0.986969 | 8.1E-166 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | sensitivity | 18225 | cg27243685 | chr21:43642366 | ABCG1 | -1.04047 | 2.7E-139 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg27243685 | chr21:43642366 | ABCG1 | 0.93 | 1.3E-137 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.2 | 4E-109 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg27243685 | chr21:43642366 | ABCG1 | 0.82 | 4.7E-107 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg27243685 | chr21:43642366 | ABCG1 | 0.92 | 3.8E-103 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.18 | 3.6E-95 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg27243685 | chr21:43642366 | ABCG1 | 0.76 | 2.3E-92 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg27243685 | chr21:43642366 | ABCG1 | 5.4 | 1.1E-84 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg27243685 | chr21:43642366 | ABCG1 | 0.82 | 9.8E-81 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.18 | 7.1E-72 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.15 | 3E-71 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.14 | 1.1E-67 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.154066 | 2E-67 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | sensitivity | 17304 | cg27243685 | chr21:43642366 | ABCG1 | 0.73 | 2.2E-64 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.14 | 8.9E-61 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.12137 | 2.9E-49 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.12 | 3.6E-44 |
| Josephine Robertson | 41361833 | DNA methylation | Q13790 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.124295 | 4.6E-44 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.12 | 2.3E-42 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Basic model | 17749 | cg27243685 | chr21:43642366 | ABCG1 | 0.1 | 4.6E-41 |
| Sayols-Baixeras S | 28173150 | Serum triglycerides | DNA methylation | Whole blood | Replication adjusted for surrogate variables | 2542 | cg27243685 | chr21:43642366 | ABCG1 | 0.065 | 2.6E-38 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.115166 | 4.6E-38 |
| Josephine Robertson | 41361833 | DNA methylation | Q13790 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.105062 | 2.8E-37 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent Type 2 Diabetes (Self-report) | Whole blood | Basic model | 18005 | cg27243685 | chr21:43642366 | ABCG1 | 0.22 | 3.5E-37 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3922444 (gene symbol: ABCG1) | Whole blood | Meta-analysis | 4170 | cg27243685 | chr21:43642366 | ABCG1 | NA | 1.3E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.1 | 4.6E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.12 | 5E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.099 | 2.7E-33 |
| Josephine Robertson | 41361833 | DNA methylation | Q15848 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.103134 | 8.3E-31 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.1 | 8.9E-31 |
| Wahl S | 28002404 | Body mass index | DNA methylation | Whole blood | Discovery and replication | 10238 | cg27243685 | chr21:43642366 | ABCG1 | NA | 1.3E-30 |
| Sayols-Baixeras S | 28173150 | Serum high-density lipoprotein cholesterol | DNA methylation | Whole blood | Replication adjusted for surrogate variables | 2542 | cg27243685 | chr21:43642366 | ABCG1 | -4.54 | 2.8E-30 |
| Hannah M. Smith | 39706196 | DNA methylation | Glucose | Whole blood | sensitivity | 17908 | cg27243685 | chr21:43642366 | ABCG1 | 0.48 | 4.8E-30 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.093 | 9.1E-30 |
| Sayols-Baixeras S | 28173150 | Serum triglycerides | DNA methylation | Whole blood | Replication | 2542 | cg27243685 | chr21:43642366 | ABCG1 | 0.047 | 6.7E-28 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0940486 | 2.3E-27 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.096 | 7.8E-27 |
| Hedman AK | 28213390 | DNA methylation | Serum triglycerides | Whole blood | Discovery | 2306 | cg27243685 | chr21:43642366 | ABCG1 | 0.012 | 8.1E-26 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0865281 | 8.7E-26 |
| Hannah M. Smith | 39706196 | DNA methylation | Glucose | Whole blood | discovery | 17908 | cg27243685 | chr21:43642366 | ABCG1 | 0.38 | 2.8E-25 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0926907 | 3.1E-25 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.092 | 6.5E-25 |
| Hedman AK | 28213390 | DNA methylation | Serum triglycerides | Whole blood | Discovery and replication | 4261 | cg27243685 | chr21:43642366 | ABCG1 | 0.0081 | 1.5E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0904292 | 3.2E-24 |
| Josephine Robertson | 41361833 | DNA methylation | Q15848 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.105469 | 3.3E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0902339 | 5.7E-24 |
| Josephine Robertson | 41361833 | DNA methylation | Q15848 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0828963 | 8.5E-24 |
| Josephine Robertson | 41361833 | DNA methylation | Q08380 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.089 | 1.9E-23 |
| Wahl S | 28002404 | Body mass index | DNA methylation | Whole blood | European ancestry discovery | 2707 | cg27243685 | chr21:43642366 | ABCG1 | 45.0 | 1.4E-22 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0864941 | 3.2E-22 |
| Sayols-Baixeras S | 28173150 | Serum high-density lipoprotein cholesterol | DNA methylation | Whole blood | Replication | 2542 | cg27243685 | chr21:43642366 | ABCG1 | -3.218 | 5.1E-22 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.085 | 1.1E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.078 | 1.8E-21 |
| Josephine Robertson | 41361833 | DNA methylation | O14791 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.085 | 2.2E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.084 | 2.9E-21 |
| Demerath EW | 25935004 | DNA methylation | Body mass index | Leukocytes, whole blood and CD4+ T cells | Meta-analysis | 5464 | cg27243685 | chr21:43642366 | ABCG1 | NA | 4.2E-21 |
| Wahl S | 28002404 | Body mass index | DNA mehtylation | Whole blood | All ancestry discovery | 5387 | cg27243685 | chr21:43642366 | ABCG1 | 31.0 | 8.2E-21 |
| Hedman AK | 28213390 | DNA methylation | Serum high-density lipoprotein cholesterol | Whole blood | Discovery and replication | 3889 | cg27243685 | chr21:43642366 | ABCG1 | -0.0002449 | 2E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0815442 | 7.2E-20 |
| Josephine Robertson | 41361833 | DNA methylation | Q15848 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0827291 | 7.7E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.094 | 1.1E-19 |
| Josephine Robertson | 41361833 | DNA methylation | Q08380 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.075 | 1.3E-19 |
| Josephine Robertson | 41361833 | DNA methylation | O14791 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.094 | 1.3E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.074155 | 2.4E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0889553 | 2.4E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.093 | 2.7E-19 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Fully-adjusted model | 13971 | cg27243685 | chr21:43642366 | ABCG1 | 0.075 | 2.9E-19 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent Ischemic Heart Disease (Self-report) | Whole blood | Basic model | 18059 | cg27243685 | chr21:43642366 | ABCG1 | 0.16 | 4.6E-19 |
| Hedman AK | 28213390 | DNA methylation | Serum high-density lipoprotein cholesterol | Whole blood | Discovery | 2306 | cg27243685 | chr21:43642366 | ABCG1 | -0.0002816 | 9.3E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.092 | 1.2E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.092 | 1.3E-18 |
| Josephine Robertson | 41361833 | DNA methylation | O14791 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.073 | 1.4E-18 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.072 | 1.9E-18 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | XS-VLDL-TG_pct | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 1.9 | 2.8E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0717482 | 3.3E-18 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | M-VLDL-TG | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 5.1 | 4E-18 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-VLDL-CE_pct | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | -1.55 | 4.4E-18 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-VLDL-C_pct | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | -1.09 | 4.8E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0713626 | 5E-18 |
| Hedman AK | 28213390 | DNA methylation | Serum triglycerides | Whole blood | Discovery adjusted for BMI | 2306 | cg27243685 | chr21:43642366 | ABCG1 | 0.01 | 5.1E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.077 | 6.4E-18 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | VLDL-TG | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 4.4 | 7.3E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.070989 | 7.4E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P36955 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.077 | 8.9E-18 |
| Hedman AK | 28213390 | DNA methylation | Serum triglycerides | Whole blood | Discovery and replication adjusted for BMI | 4261 | cg27243685 | chr21:43642366 | ABCG1 | 0.0071 | 1.6E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.086 | 2E-17 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-VLDL-TG | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 3.7 | 4.8E-17 |
| Josephine Robertson | 41361833 | DNA methylation | Q13790 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0732952 | 1.1E-16 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent Type 2 Diabetes (Self-report) | Whole blood | Fully-adjusted model | 14350 | cg27243685 | chr21:43642366 | ABCG1 | 0.15 | 1.7E-16 |
| Braun KVE | 28194238 | DNA methylation | High-density lipoprotein cholesterol | Whole blood | Discovery and replication | 1485 | cg27243685 | chr21:43642366 | ABCG1 | -0.0105 | 2.8E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0841293 | 3.3E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.082 | 6.6E-16 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Fully-adjusted model | 14040 | cg27243685 | chr21:43642366 | ABCG1 | 2.3 | 7.1E-16 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | M-VLDL-P | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 4.1 | 1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.065651 | 1.7E-15 |
| Mendelson MM | 28095459 | DNA methylation | Body mass index | Whole blood | Meta-analysis | 3743 | cg27243685 | chr21:43642366 | ABCG1 | NA | 2.3E-15 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | Serum-TG | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 3.1 | 2.3E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.065 | 2.5E-15 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | M-VLDL-L | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 4.0 | 4E-15 |
| Josephine Robertson | 41361833 | DNA methylation | C9JB55 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.082 | 4.6E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P00742 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.069 | 8.5E-15 |
| Braun KVE | 28194238 | DNA methylation | Triglycerides | Whole blood | Discovery and replication | 1485 | cg27243685 | chr21:43642366 | ABCG1 | 0.0085 | 9.9E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.08 | 1.3E-14 |
| Mendelson MM | 28095459 | DNA methylation | Body mass index | Whole blood | Framingham Heart Study Batch 2 | 1935 | cg27243685 | chr21:43642366 | ABCG1 | 0.032 | 1.4E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P36955 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.063 | 1.6E-14 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | L-VLDL-P | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 9.0 | 1.7E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0693285 | 1.7E-14 |
| Demerath EW | 25935004 | DNA methylation | Body mass index | Whole blood and CD4+ T cells | Replication | 3368 | cg27243685 | chr21:43642366 | ABCG1 | NA | 1.9E-14 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | L-VLDL-L | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 8.9 | 2.1E-14 |
| Josephine Robertson | 41361833 | DNA methylation | C9JB55 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.069 | 3.9E-14 |
| Liu J | 31197173 | DNA methylation | fasting insulin | whole blood | Base | 4808 | cg27243685 | chr21:43642366 | ABCG1 | 3.3 | 4E-14 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | M-VLDL-PL | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 3.7 | 4.3E-14 |
| Josephine Robertson | 41361833 | DNA methylation | O14791 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.069 | 4.3E-14 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | M-VLDL-FC | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 4.3 | 4.5E-14 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-HDL-TG | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 2.0 | 5E-14 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | L-VLDL-TG | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 10.0 | 7.8E-14 |
| Jiantao Ma | 30796027 | DNA methylation | hepatic fat | whole blood | Discovery | 1496 | cg27243685 | chr21:43642366 | ABCG1 | NA | 1.2E-13 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | IDL.TG_pct | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 1.7 | 1.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0610045 | 1.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.061 | 1.5E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00742 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.06 | 2.6E-13 |
| Pfeiffer L | 25583993 | Triglycerides | DNA methylation | Whole blood | Discovery | 1776 | cg27243685 | chr21:43642366 | ABCG1 | 0.064 | 3.2E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.06 | 3.7E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0596836 | 4.7E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0744537 | 4.9E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.065 | 5.7E-13 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | XS-VLDL-TG | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 2.3 | 6.3E-13 |
| Ma J | 30936141 | DNA methylation | Hepatic Fat | Whole blood | Meta-analysis model 1 | 3400 | cg27243685 | chr21:43642366 | ABCG1 | NA | 6.8E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.059 | 6.9E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.074 | 9.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | Q13790 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.072035 | 1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.064 | 1.6E-12 |
| Hedman AK | 28213390 | DNA methylation | Serum high-density lipoprotein cholesterol | Whole blood | Discovery and replication adjusted for BMI | 3889 | cg27243685 | chr21:43642366 | ABCG1 | -0.0001971 | 1.7E-12 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.063 | 1.7E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0582027 | 1.7E-12 |
| Ma J | 30936141 | DNA methylation | Hepatic Fat | Whole blood | Meta-analysis model 2 | 3400 | cg27243685 | chr21:43642366 | ABCG1 | NA | 2.1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0634637 | 2.1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0577513 | 2.6E-12 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-HDL-TG_pct | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 1.9 | 3.7E-12 |
| Josephine Robertson | 41361833 | DNA methylation | C9JB55 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.062 | 4.1E-12 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-VLDL-P | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 2.3 | 4.2E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | sensitivity | 18270 | cg27243685 | chr21:43642366 | ABCG1 | -0.289497 | 4.8E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0607767 | 5E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02743 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.062 | 5.4E-12 |
| Wahl S | 28002404 | Body mass index | DNA methylation | Whole blood | All ancestry replication | 4851 | cg27243685 | chr21:43642366 | ABCG1 | 17.0 | 6.7E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.062 | 6.8E-12 |
| Josephine Robertson | 41361833 | DNA methylation | O95445 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0608013 | 1.1E-11 |
| Demerath EW | 25935004 | DNA methylation | Waist circumference | Leukocytes | Discovery | 2097 | cg27243685 | chr21:43642366 | ABCG1 | 0.0069 | 1.4E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.056 | 1.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0597621 | 2E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0550492 | 2.5E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.06 | 2.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0594556 | 2.8E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.060129 | 3.2E-11 |
| Hedman AK | 28213390 | DNA methylation | Serum high-density lipoprotein cholesterol | Whole blood | Discovery adjusted for BMI | 2306 | cg27243685 | chr21:43642366 | ABCG1 | -0.0002228 | 3.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | Q08380 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.059 | 4.6E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.06 | 5.3E-11 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-VLDL-L | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 2.1 | 6.3E-11 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-VLDL-PL | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 2.0 | 9E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.067 | 9.3E-11 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.067 | 1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.057 | 1.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0661119 | 1.4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.058 | 1.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.057 | 1.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0643501 | 2.4E-10 |
| Sayols-Baixeras S | 28173150 | Serum triglycerides | DNA methylation | Whole blood | Discovery adjusted for surrogate variables | 645 | cg27243685 | chr21:43642366 | ABCG1 | 0.061 | 2.5E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0635173 | 2.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.056 | 3.1E-10 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-LDL-TG_pct | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 1.6 | 3.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0623631 | 4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0558422 | 4.2E-10 |
| Petersen A-K | 24014485 | M35718_dihomo-linolenate_20:3n3_or_n6 | DNA methylation | Whole blood | snps as covariates model | 1760 | cg27243685 | chr21:43642366 | ABCG1 | -0.93 | 4.7E-10 |
| Petersen A-K | 24014485 | M35718_dihomo-linolenate_20:3n3_or_n6 | DNA methylation | Whole blood | no snps model | 1760 | cg27243685 | chr21:43642366 | ABCG1 | -0.93 | 4.8E-10 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent Ischemic Heart Disease (Self-report) | Whole blood | Fully-adjusted model | 14391 | cg27243685 | chr21:43642366 | ABCG1 | 0.12 | 5.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.064 | 7.4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.056 | 9.4E-10 |
| Wahl S | 28002404 | Body mass index | DNA methylation | Whole blood | European ancestry replication | 4195 | cg27243685 | chr21:43642366 | ABCG1 | 12.0 | 1.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0535853 | 2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | Q08380 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.062 | 2.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P00742 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.055 | 2.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.054 | 3E-09 |
| Gadd DA | 35945220 | HMGCS1 protein levels (SeqId = 13496-19) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 1.1 | 3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.052 | 5.5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0518946 | 5.7E-09 |
| Ochoa-Rosales C | 32033992 | Statin use | DNA methylation | Whole blood | Discovery | 6820 | cg27243685 | chr21:43642366 | ABCG1 | 0.0044 | 6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P69905 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0519806 | 6.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0510811 | 1.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00742 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.059 | 1.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0570569 | 1.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0586313 | 1.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | C9JB55 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.047 | 1.7E-08 |
| Wahl S | 28002404 | Body mass index | DNA methylation | Whole blood | South Asian ancestry discovery | 2680 | cg27243685 | chr21:43642366 | ABCG1 | 22.0 | 1.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.046 | 2.4E-08 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-VLDL-FC | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 1.9 | 2.4E-08 |
| Demerath EW | 25935004 | DNA methylation | Body mass index | Leukocytes | Discovery | 2096 | cg27243685 | chr21:43642366 | ABCG1 | 0.0057 | 3.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.049 | 4.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0490596 | 4.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.045 | 4.5E-08 |
| Sayols-Baixeras S | 28173150 | Serum triglycerides | DNA methylation | Whole blood | Discovery | 645 | cg27243685 | chr21:43642366 | ABCG1 | 0.044 | 6.5E-08 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | M-HDL-TG | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 1.7 | 6.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.044 | 7E-08 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent Stroke (Self-report) | Whole blood | Basic model | 18056 | cg27243685 | chr21:43642366 | ABCG1 | 0.068 | 9.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.055 | 1.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.044 | 1.3E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | discovery | 18270 | cg27243685 | chr21:43642366 | ABCG1 | -0.190909 | 1.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02743 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.043 | 1.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P80108 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.043 | 1.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O95445 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0430731 | 1.8E-07 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | L-LDL-FC_pct | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | -0.35 | 1.8E-07 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | S-LDL-TG | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 1.8 | 2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.047 | 2.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0470809 | 2.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02760 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0459349 | 2.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0533109 | 3.4E-07 |
| Liu J | 31197173 | DNA methylation | fasting insulin | whole blood | Base plus BMI | 4808 | cg27243685 | chr21:43642366 | ABCG1 | 2.0 | 3.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0418685 | 3.9E-07 |
| Xu K | 27826092 | DNA methylation | Body mass index | Whole blood | - | 510 | cg27243685 | chr21:43642366 | ABCG1 | 0.0009 | 4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P80108 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.045 | 5.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.044 | 7.6E-07 |
| Wahl S | 28002404 | Body mass index | DNA methylation | Whole blood | South Asian ancestry replication | 656 | cg27243685 | chr21:43642366 | ABCG1 | 60.0 | 8.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0439788 | 8.8E-07 |
| Gadd DA | 35945220 | GPD1 protein levels (SeqId = 13697-51) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.91 | 9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0513066 | 9.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P36955 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.05 | 9.8E-07 |
| Ma J | 30936141 | Nonalcoholic fatty liver disease | DNA methylation | Whole Blood, Monocytes | discovery and replication | 4525 | cg27243685 | chr21:43642366 | ABCG1 | NA | 1.2E-06 |
| Ma J | 30936141 | DNA methylation | Hepatic Fat | Whole blood | Meta-analysis model 3 | 3400 | cg27243685 | chr21:43642366 | ABCG1 | NA | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.05 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.042 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0429664 | 2.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.048 | 2.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.039 | 2.6E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg27243685 | chr21:43642366 | ABCG1 | -0.00083 | 2.7E-06 |
| Gadd DA | 35945220 | PSAT1 protein levels (SeqId = 18342-2) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.87 | 2.7E-06 |
| Mamtani M | 26798409 | Liability function of hypertriglyceridemic waist | DNA methylation | Peripheral blood | - | 850 | cg27243685 | chr21:43642366 | ABCG1 | -0.28441292 | 3.2E-06 |
| Battram T | None | DNA methylation | Triglycerides in medium HDL | Whole blood | None | 683 | cg27243685 | chr21:43642366 | ABCG1 | 10.0 | 3.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.039 | 3.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02760 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0381838 | 3.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P20851 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.041 | 3.9E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Ischemic Heart Disease | Whole blood | Basic model | 17483 | cg27243685 | chr21:43642366 | ABCG1 | 0.034 | 4E-06 |
| Gadd DA | 35945220 | CPM protein levels (SeqId = 9416-77) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.85 | 4.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0417764 | 4.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.041 | 4.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.04 | 4.8E-06 |
| Battram T | None | DNA methylation | Triglycerides in small HDL | Whole blood | None | 682 | cg27243685 | chr21:43642366 | ABCG1 | 10.0 | 5.2E-06 |
| Sayols-Baixeras S | 28173150 | Serum high-density lipoprotein cholesterol | DNA methylation | Whole blood | Discovery | 645 | cg27243685 | chr21:43642366 | ABCG1 | -2.438 | 5.7E-06 |
| Gadd DA | 35945220 | SDCBP protein levels (SeqId = 17806-6) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.84 | 5.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0404682 | 6.2E-06 |
| Ochoa-Rosales C | 32033992 | Statin use | DNA methylation | Whole blood | Replication | 1450 | cg27243685 | chr21:43642366 | ABCG1 | 0.0069 | 6.4E-06 |
| Battram T | None | DNA methylation | Total cholesterol to total lipids ratio in very small VLDL | Whole blood | None | 678 | cg27243685 | chr21:43642366 | ABCG1 | -0.036 | 6.9E-06 |
| Battram T | None | DNA methylation | Total lipids in small HDL | Whole blood | None | 685 | cg27243685 | chr21:43642366 | ABCG1 | 1.1 | 7.9E-06 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | TGtoPG | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 2.5 | 9E-06 |
| Gadd DA | 35945220 | ADH4 protein levels (SeqId = 8325-37) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.82 | 9E-06 |
| Gadd DA | 35945220 | RET protein levels (SeqId = 3220-40) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.82 | 9.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0395787 | 9.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.04 | 9.8E-06 |
| Jiantao Ma | 30796027 | DNA methylation | hepatic fat | whole blood | Replication | 1904 | cg27243685 | chr21:43642366 | ABCG1 | NA | 1.1E-05 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | MUFA | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | 1.1 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0362137 | 1.1E-05 |
| Battram T | None | DNA methylation | Triglycerides to total lipids ratio in medium HDL | Whole blood | None | 683 | cg27243685 | chr21:43642366 | ABCG1 | 0.1 | 1.2E-05 |
| Gadd DA | 35945220 | FAH protein levels (SeqId = 11424-4) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.81 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P69905 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0398004 | 1.3E-05 |
| Gadd DA | 35945220 | ASL protein levels (SeqId = 11241-8) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.8 | 1.3E-05 |
| Gadd DA | 35945220 | ACY1 protein levels (SeqId = 3343-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.81 | 1.3E-05 |
| Gadd DA | 35945220 | INSL5 protein levels (SeqId = 10462-14) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.8 | 1.5E-05 |
| Battram T | None | DNA methylation | Triglycerides in IDL | Whole blood | None | 683 | cg27243685 | chr21:43642366 | ABCG1 | 3.9 | 1.6E-05 |
| Battram T | None | DNA methylation | Triglycerides in very small VLDL | Whole blood | None | 680 | cg27243685 | chr21:43642366 | ABCG1 | 3.7 | 1.7E-05 |
| Gadd DA | 35945220 | FBP1 protein levels (SeqId = 7206-20) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.79 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P69905 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0353173 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0388125 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43251 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.035 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.03892 | 2E-05 |
| Gadd DA | 35945220 | FKBP6 protein levels (SeqId = 12529-32) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.79 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.041 | 2E-05 |
| Sayols-Baixeras S | 28173150 | Serum high-density lipoprotein cholesterol | DNA methylation | Whole blood | Discovery adjusted for surrogate variables | 645 | cg27243685 | chr21:43642366 | ABCG1 | -1.665 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.039 | 2.2E-05 |
| Gadd DA | 35945220 | RBP5 protein levels (SeqId = 19241-31) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.78 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0434794 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.038 | 2.5E-05 |
| Pfeiffer L | 25583993 | Triglycerides | DNA methylation | Whole blood | Replication | 971 | cg27243685 | chr21:43642366 | ABCG1 | NA | 2.5E-05 |
| Battram T | 27886173 | DNA methylation | Crohn's disease | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 | 161 | cg27243685 | chr21:43642366 | ABCG1 | -0.0132 | 2.5E-05 |
| Gomez-Alonso MDC | 33413638 | DNA methylation | XS-VLDL-C_pct | Whole blood | Meta-analysis | 5414 | cg27243685 | chr21:43642366 | ABCG1 | -0.57 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0438435 | 2.7E-05 |
| Gadd DA | 35945220 | DEFB1 protein levels (SeqId = 6629-3) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.77 | 3E-05 |
| Gadd DA | 35945220 | GEM protein levels (SeqId = 12817-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.77 | 3.2E-05 |
| Battram T | None | DNA methylation | Cholesterol esters to total lipids ratio in medium HDL | Whole blood | None | 683 | cg27243685 | chr21:43642366 | ABCG1 | -0.063 | 3.3E-05 |
| Gadd DA | 35945220 | SORD protein levels (SeqId = 15447-45) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.77 | 3.5E-05 |
| Battram T | None | DNA methylation | Total body mass | Whole blood | None | 704 | cg27243685 | chr21:43642366 | ABCG1 | 8.8e-06 | 3.6E-05 |
| Gadd DA | 35945220 | PTPRU protein levels (SeqId = 8337-65) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.76 | 3.7E-05 |
| Battram T | None | DNA methylation | Total tissue mass | Whole blood | None | 704 | cg27243685 | chr21:43642366 | ABCG1 | 8.9e-06 | 3.7E-05 |
| Battram T | None | DNA methylation | VLDL cholesterol | Whole blood | fasting | 678 | cg27243685 | chr21:43642366 | ABCG1 | 0.66 | 3.7E-05 |
| Hedman AK | 28213390 | DNA methylation | Serum triglycerides | Whole blood | Replication | 1955 | cg27243685 | chr21:43642366 | ABCG1 | 0.0045 | 3.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.037 | 3.8E-05 |
| Battram T | None | DNA methylation | Trunk total mass | Whole blood | None | 699 | cg27243685 | chr21:43642366 | ABCG1 | 1.6e-05 | 3.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0339821 | 3.8E-05 |
| Battram T | None | DNA methylation | Triglycerides | Whole blood | fasting | 678 | cg27243685 | chr21:43642366 | ABCG1 | 0.3 | 3.9E-05 |
| Joubert BR | 27040690 | DNA methylation | Maternal smoking in pregnancy | Cord blood | Any maternal smoking in pregnancy effect on newborns | 6685 | cg27243685 | chr21:43642366 | ABCG1 | 0.003 | 4E-05 |
| Battram T | None | DNA methylation | Trunk tissue mass | Whole blood | None | 699 | cg27243685 | chr21:43642366 | ABCG1 | 1.6e-05 | 4.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.034 | 4.3E-05 |
| Battram T | None | DNA methylation | Total cholesterol to total lipids ratio in medium HDL | Whole blood | None | 682 | cg27243685 | chr21:43642366 | ABCG1 | -0.062 | 4.4E-05 |
| Battram T | None | DNA methylation | Phospholipids in small VLDL | Whole blood | None | 683 | cg27243685 | chr21:43642366 | ABCG1 | 2.8 | 4.8E-05 |
| Gadd DA | 35945220 | IL18R1 protein levels (SeqId = 14079-14) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.75 | 4.8E-05 |
| Gadd DA | 35945220 | ALDOB protein levels (SeqId = 18185-118) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.75 | 4.9E-05 |
| Gadd DA | 35945220 | NEU1 protein levels (SeqId = 15426-5) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.75 | 5.1E-05 |
| Gadd DA | 35945220 | ALDOC protein levels (SeqId = 9876-20) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.75 | 5.1E-05 |
| Gadd DA | 35945220 | AKR7A3 protein levels (SeqId = 18173-11) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.75 | 5.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0357332 | 5.2E-05 |
| Gadd DA | 35945220 | HTRA1 protein levels (SeqId = 15594-47) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.75 | 5.4E-05 |
| Gadd DA | 35945220 | SELE protein levels (SeqId = 3470-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.75 | 5.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0366944 | 5.6E-05 |
| Battram T | None | DNA methylation | Cholesterol esters to total lipids ratio in very small VLDL | Whole blood | None | 680 | cg27243685 | chr21:43642366 | ABCG1 | -0.036 | 5.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20851 | whole blood | OSCA model 1 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | 0.033 | 5.9E-05 |
| Gadd DA | 35945220 | UGDH protein levels (SeqId = 17755-5) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.74 | 6E-05 |
| Gadd DA | 35945220 | INHBA protein levels (SeqId = 19622-7) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.74 | 6.3E-05 |
| Battram T | None | DNA methylation | Concentration of small VLDL particles | Whole blood | None | 681 | cg27243685 | chr21:43642366 | ABCG1 | 13000000.0 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O95445 | whole blood | OSCA model 3 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0360272 | 7.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 2 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.035293 | 7.7E-05 |
| Gadd DA | 35945220 | DSG2 protein levels (SeqId = 9484-75) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | -0.73 | 7.8E-05 |
| Battram T | None | DNA methylation | Total cholesterol to total lipids ratio in large HDL | Whole blood | None | 678 | cg27243685 | chr21:43642366 | ABCG1 | -0.034 | 8.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O95445 | whole blood | OSCA model 4 | 14671 | cg27243685 | chr21:43642366 | ABCG1 | -0.0408954 | 8.3E-05 |
| Battram T | None | DNA methylation | Total lipids in small VLDL | Whole blood | None | 681 | cg27243685 | chr21:43642366 | ABCG1 | 0.59 | 8.7E-05 |
| Battram T | 27886173 | DNA methylation | Inflammatory bowel disease | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 | 240 | cg27243685 | chr21:43642366 | ABCG1 | 0.011 | 8.9E-05 |
| Gadd DA | 35945220 | SDCBP2 protein levels (SeqId = 19261-12) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.73 | 9E-05 |
| Battram T | None | DNA methylation | Free cholesterol in small VLDL | Whole blood | None | 683 | cg27243685 | chr21:43642366 | ABCG1 | 4.0 | 9.1E-05 |
| Gadd DA | 35945220 | NFASC protein levels (SeqId = 7179-69) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.72 | 9.2E-05 |
| Gadd DA | 35945220 | HRSP12 protein levels (SeqId = 14636-25) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.72 | 9.3E-05 |
| Gadd DA | 35945220 | OTC protein levels (SeqId = 15431-31) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.72 | 9.7E-05 |
| Gadd DA | 35945220 | ALDH1A1 protein levels (SeqId = 11265-8) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27243685 | chr21:43642366 | ABCG1 | 0.72 | 9.9E-05 |
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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.
