Search results for APBB2
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01058879 | chr4:40823935 | APBB2 | -0.002 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01322290 | chr4:40818120 | APBB2 | -0.0049 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg02694037 | chr4:41125894 | APBB2 | -0.0032 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg04494059 | chr4:40818170 | APBB2 | -0.0016 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg05057585 | chr4:41213424 | APBB2 | -0.003 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg06970472 | chr4:40910981 | APBB2 | -0.0019 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg07291349 | chr4:40964962 | APBB2 | -0.01 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg08016336 | chr4:41181318 | APBB2 | -0.00086 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg08174482 | chr4:40823896 | APBB2 | -0.0019 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg08670693 | chr4:41162197 | APBB2 | -0.00058 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg13690063 | chr4:40921171 | APBB2 | -0.0026 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg13978856 | chr4:40918191 | APBB2 | -0.0021 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg14309469 | chr4:40817953 | APBB2 | -0.0018 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg15563027 | chr4:41215455 | APBB2 | 0.0019 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg15989892 | chr4:41063747 | APBB2 | -0.0036 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg16433074 | chr4:41050961 | APBB2 | -0.00065 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg17699214 | chr4:40890013 | APBB2 | -0.001 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg18401298 | chr4:40890484 | APBB2 | -0.00084 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg21593628 | chr4:40890812 | APBB2 | -0.0034 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg22179055 | chr4:41207235 | APBB2 | -0.0025 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg23884217 | chr4:41147318 | APBB2 | -0.0021 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg23968551 | chr4:40818214 | APBB2 | -0.0046 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg24644605 | chr4:40944984 | APBB2 | -0.0019 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg26244738 | chr4:40859344 | APBB2 | 0.00061 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg27434086 | chr4:41218082 | APBB2 | 0.0051 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg27434086 | chr4:41218082 | APBB2 | -0.019 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg27434086 | chr4:41218082 | APBB2 | -0.024 | 0E+00 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg27434086 | chr4:41218082 | APBB2 | 0.47 | 6.3E-132 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg02650667 | chr4:41072974 | APBB2 | 0.61 | 4E-129 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg23753351 | chr4:40860327 | APBB2 | -0.44328 | 3.3E-126 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg11404380 | chr4:41215359 | APBB2 | 0.17 | 3.5E-108 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.179151 | 4.5E-106 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg08670693 | chr4:41162197 | APBB2 | 0.41 | 2.2E-103 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.172263 | 4.2E-98 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.172068 | 7E-98 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg25333257 | chr4:41217803 | APBB2 | 0.12 | 2.9E-95 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.165393 | 1.8E-90 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg13978856 | chr4:40918191 | APBB2 | 0.31 | 6.5E-87 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg19542542 | chr4:41157025 | APBB2 | 0.14 | 3E-86 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.157671 | 2.7E-82 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.151465 | 5.1E-76 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.149852 | 2E-74 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.138689 | 6.4E-64 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg24644605 | chr4:40944984 | APBB2 | -0.09059 | 1.4E-63 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg06970472 | chr4:40910981 | APBB2 | 0.14 | 5E-62 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg01954188 | chr4:41216800 | APBB2 | 0.028 | 1E-60 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.133522 | 2.5E-59 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.13321 | 4.6E-59 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg05020685 | chr4:40858965 | APBB2 | 0.00054 | 7.1E-59 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg24992745 | chr4:41215654 | APBB2 | 0.067 | 4.8E-56 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.128236 | 7.8E-55 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.125325 | 2E-52 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg05020685 | chr4:40858965 | APBB2 | -4.39004 | 2.4E-51 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.122279 | 5.5E-50 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.118013 | 1.2E-46 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.117959 | 1.3E-46 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.12 | 3.9E-46 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg17699214 | chr4:40890013 | APBB2 | -0.04182 | 1.8E-45 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg08016336 | chr4:41181318 | APBB2 | -0.04123 | 6.7E-43 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.11 | 2.2E-40 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg23735712 | chr4:40858984 | APBB2 | -4.59814 | 4.8E-40 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.11 | 6.2E-40 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg09616640 | chr4:41216812 | APBB2 | 0.024 | 1E-39 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg12455762 | chr4:40859095 | APBB2 | -3.14013 | 7.9E-39 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg02650667 | chr4:41072974 | APBB2 | NA | 9.3E-39 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg03870448 | chr4:41214687 | APBB2 | 2.7 | 1.4E-38 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.106228 | 4.4E-38 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.11 | 9.6E-38 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.105382 | 1.7E-37 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.11 | 2.9E-37 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.104778 | 4.3E-37 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg27495108 | chr4:41216882 | APBB2 | 0.02 | 1.6E-36 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg14290210 | chr4:41162942 | APBB2 | NA | 2.4E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.103132 | 5.5E-36 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg06485940 | chr4:40859293 | APBB2 | -3.08965 | 6E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.1 | 6.1E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.1 | 7.5E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.1 | 7.9E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.102457 | 1.6E-35 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.102128 | 2.6E-35 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.101344 | 8.4E-35 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg16364495 | chr4:40859251 | APBB2 | -3.94001 | 2.2E-34 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg22179055 | chr4:41207235 | APBB2 | 0.0013 | 2.8E-34 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.100487 | 3.1E-34 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0998106 | 8.4E-34 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.1 | 9.2E-34 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.099 | 1.7E-33 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0985657 | 5.3E-33 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.097 | 5.6E-32 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0964878 | 1.1E-31 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.095 | 5.2E-31 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg02379560 | chr4:40859280 | APBB2 | -3.20219 | 5.9E-31 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0945765 | 1.7E-30 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg22913249 | chr4:41215979 | APBB2 | 0.00025 | 2.5E-30 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0938082 | 4.9E-30 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.094 | 5.7E-30 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg16552881 | chr4:40839375 | APBB2 | -0.03064 | 7.5E-30 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.093 | 9.9E-30 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.093 | 1.9E-29 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0926116 | 2.6E-29 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.093 | 2.9E-29 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.092 | 3.2E-29 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0924362 | 3.3E-29 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.092 | 4.8E-29 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg23753351 | chr4:40860327 | APBB2 | -1.66761 | 1.5E-28 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.091 | 2.2E-28 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0906875 | 3.6E-28 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg07291349 | chr4:40964962 | APBB2 | -0.06452 | 1.2E-27 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | -0.0891854 | 2.7E-27 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg05894734 | chr4:40859249 | APBB2 | -3.093 | 2.8E-27 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg22913249 | chr4:41215979 | APBB2 | 0.02 | 2.9E-27 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | -0.088076 | 1.2E-26 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.088 | 1.7E-26 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg11404380 | chr4:41215359 | APBB2 | 1.6 | 5.1E-26 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0860354 | 1.6E-25 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg05057585 | chr4:41213424 | APBB2 | 0.0024 | 2.2E-25 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0857232 | 2.4E-25 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg23753351 | chr4:40860327 | APBB2 | 0.0019 | 2.9E-25 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.085 | 3.5E-25 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg15989892 | chr4:41063747 | APBB2 | NA | 1E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0844037 | 1.3E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | -0.0843686 | 1.4E-24 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg08106124 | chr4:40926641 | APBB2 | NA | 1.6E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.084 | 2E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | 0.083 | 4.4E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.083 | 5.7E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.083 | 5.9E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0831032 | 6.6E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.083 | 8.2E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0828594 | 8.9E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0828145 | 9.4E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.082 | 1.4E-23 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0823923 | 1.6E-23 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0817227 | 3.6E-23 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg15563027 | chr4:41215455 | APBB2 | 0.034 | 3.8E-23 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.082 | 4.2E-23 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.081 | 1.3E-22 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0806069 | 1.4E-22 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.081 | 1.5E-22 |
| Marttila S | 25888029 | DNA methylation | Age group | Peripheral blood mononuclear cells | - | 143 | cg06970472 | chr4:40910981 | APBB2 | -0.69410498 | 2E-22 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | 0.08 | 4E-22 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.08 | 4.6E-22 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg26865481 | chr4:41206196 | APBB2 | -0.02615 | 1.8E-21 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg04917391 | chr4:40859259 | APBB2 | -2.32101 | 1.9E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0780087 | 3E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0775184 | 5.3E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.077 | 1.1E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.077 | 1.5E-20 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg25886371 | chr4:40917710 | APBB2 | -0.324869 | 1.5E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | 0.076 | 1.7E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.076 | 1.9E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0763099 | 2.1E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.076215 | 2.4E-20 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg13690063 | chr4:40921171 | APBB2 | 0.0017 | 3.3E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg00132598 | chr4:41016918 | APBB2 | 0.076 | 4.5E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.076 | 4.9E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.075 | 5.6E-20 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg23877017 | chr4:40969729 | APBB2 | 0.035 | 9.1E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.082 | 9.2E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | -0.0746247 | 1.4E-19 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg08424587 | chr4:41216479 | APBB2 | 0.0081 | 2.3E-19 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg07291349 | chr4:40964962 | APBB2 | 2.2 | 2.5E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.074 | 3.4E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0737262 | 3.8E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | 0.074 | 4.2E-19 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0806523 | 4.2E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | 0.073 | 9.9E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.073 | 1.1E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.073 | 1.2E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | 0.072 | 1.6E-18 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg15989892 | chr4:41063747 | APBB2 | -0.263753 | 4E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0714357 | 4.6E-18 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg06970472 | chr4:40910981 | APBB2 | -2.5 | 4.8E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04673478 | chr4:41124815 | APBB2 | 0.071 | 5.8E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.071 | 8.5E-18 |
| Kyung WK | 32795589 | DNA methylation | eosinophilia | nasal polyp | discovery | 129 | cg12439416 | chr4:40832685 | APBB2 | -0.018 | 9.8E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | 0.071 | 1.1E-17 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg18526270 | chr4:41216855 | APBB2 | 3.7 | 1.2E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0702223 | 1.7E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0702172 | 1.7E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.07 | 2.4E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.07 | 2.7E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.07 | 3.5E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0694356 | 3.8E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0693402 | 4.2E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | 0.069 | 4.4E-17 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg08174482 | chr4:40823896 | APBB2 | 0.0015 | 5.7E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.069 | 6.3E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.069 | 6.4E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0688987 | 6.6E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | 0.069 | 7.8E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0686534 | 8.5E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.069 | 9.7E-17 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.068 | 1.1E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0682941 | 1.2E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.074 | 1.5E-16 |
| Marttila S | 25888029 | DNA methylation | Age group | Peripheral blood mononuclear cells | - | 143 | cg15989892 | chr4:41063747 | APBB2 | -0.91527336 | 1.8E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.068 | 1.8E-16 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg24656517 | chr4:40844307 | APBB2 | 0.0009 | 2.2E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.068 | 2.2E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.067649 | 2.4E-16 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg16823610 | chr4:40856529 | APBB2 | 0.00068 | 2.6E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.068 | 2.6E-16 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.068 | 2.7E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0674742 | 2.8E-16 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg13978856 | chr4:40918191 | APBB2 | -0.17403 | 3.2E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | 0.067 | 3.3E-16 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg23753351 | chr4:40860327 | APBB2 | -0.3417 | 3.7E-16 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg23884217 | chr4:41147318 | APBB2 | -0.384532 | 3.9E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.067 | 4.3E-16 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg23753351 | chr4:40860327 | APBB2 | 0.0015 | 4.4E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0670133 | 4.5E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.067 | 6.3E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg02109167 | chr4:41187789 | APBB2 | 0.067 | 7.1E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | 0.066 | 9.1E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.066 | 1.3E-15 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 2724853 (gene symbol: NSUN7) | Whole blood | Meta-analysis | 4170 | cg03870448 | chr4:41214687 | APBB2 | NA | 1.4E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0658313 | 1.4E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg08016336 | chr4:41181318 | APBB2 | 0.066 | 1.9E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg02650667 | chr4:41072974 | APBB2 | -0.0025 | 2E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.065 | 2.2E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0652236 | 2.6E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg05020685 | chr4:40858965 | APBB2 | 0.00035 | 3.3E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.065 | 3.7E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.065 | 4.6E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.065 | 5.1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.064 | 6.2E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04673478 | chr4:41124815 | APBB2 | 0.064 | 6.7E-15 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.064 | 6.9E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | -0.0641943 | 7.1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.064 | 7.4E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0641361 | 7.5E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg14290210 | chr4:41162942 | APBB2 | -0.0022 | 8E-15 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg22648864 | chr4:40996373 | APBB2 | -0.38528 | 8.4E-15 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg02694037 | chr4:41125894 | APBB2 | -0.02533 | 8.6E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.064 | 9.1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | 0.064 | 9.5E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.064 | 1.1E-14 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg06970472 | chr4:40910981 | APBB2 | -0.230461 | 1.1E-14 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg06970472 | chr4:40910981 | APBB2 | -0.0071 | 1.1E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.064 | 1.1E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.063 | 1.5E-14 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg09277762 | chr4:41030552 | APBB2 | -0.27474 | 1.5E-14 |
| Nones K | 24500968 | DNA methylation | Pancreatic ductal adenocarcinoma | Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata | - | 196 | cg14290210 | chr4:41162942 | APBB2 | NA | 1.6E-14 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | -0.0633132 | 1.6E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg14464517 | chr4:41115076 | APBB2 | 0.063 | 1.9E-14 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg24656517 | chr4:40844307 | APBB2 | -0.40937 | 1.9E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0631186 | 2E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.063 | 2.2E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0629143 | 2.4E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0628591 | 2.5E-14 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | -0.0627191 | 2.9E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.063 | 3.2E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | -0.0625824 | 3.3E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.063 | 3.4E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.062 | 4.1E-14 |
| Kyung WK | 32795589 | DNA methylation | eosinophilia | nasal polyp | discovery | 129 | cg08350742 | chr4:40814531 | APBB2 | 0.017 | 4.3E-14 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg11382761 | chr4:41031037 | APBB2 | -0.00083 | 4.9E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.062 | 6.2E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg11945554 | chr4:40857255 | APBB2 | 0.062 | 7.3E-14 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0677991 | 7.5E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0616775 | 7.6E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.062 | 7.7E-14 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg04494059 | chr4:40818170 | APBB2 | -0.273809 | 8.3E-14 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg03870448 | chr4:41214687 | APBB2 | 0.0026 | 9E-14 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg16823610 | chr4:40856529 | APBB2 | -0.00061 | 9.1E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | 0.061 | 1.2E-13 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg04494059 | chr4:40818170 | APBB2 | 0.023 | 1.2E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | -0.0611484 | 1.2E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0611285 | 1.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.061 | 1.3E-13 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg24644605 | chr4:40944984 | APBB2 | -0.270438 | 1.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.061 | 1.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.061 | 1.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.067 | 1.4E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg21330088 | chr4:41198045 | APBB2 | -0.0011 | 1.5E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.061 | 1.5E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0609177 | 1.5E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0609167 | 1.5E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg15563027 | chr4:41215455 | APBB2 | 0.0015 | 1.6E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.061 | 1.7E-13 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg23884217 | chr4:41147318 | APBB2 | -0.09145 | 1.9E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg26865481 | chr4:41206196 | APBB2 | -0.0009 | 1.9E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.06 | 1.9E-13 |
| Kyung WK | 32795589 | DNA methylation | eosinophilia | nasal polyp | discovery | 129 | cg09277762 | chr4:41030552 | APBB2 | 0.053 | 2E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0605822 | 2.1E-13 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg03986691 | chr4:40857415 | APBB2 | -0.02199 | 2.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0604771 | 2.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0604203 | 2.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.06 | 3.1E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0599488 | 3.7E-13 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg18401298 | chr4:40890484 | APBB2 | -0.04256 | 3.7E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg01058879 | chr4:40823935 | APBB2 | 0.0013 | 4.1E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | -0.059779 | 4.3E-13 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg26244738 | chr4:40859344 | APBB2 | 0.0075 | 4.5E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg11945554 | chr4:40857255 | APBB2 | 0.06 | 4.6E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.059674 | 4.7E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg09616640 | chr4:41216812 | APBB2 | 0.00057 | 4.8E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0596073 | 5E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0595391 | 5.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0593782 | 6.1E-13 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg04568895 | chr4:41145263 | APBB2 | -0.265449 | 6.3E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg03870448 | chr4:41214687 | APBB2 | -0.0017 | 6.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.059 | 6.9E-13 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg08350742 | chr4:40814531 | APBB2 | -1.5 | 7.1E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.059 | 7.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.120861 | 7.6E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.059 | 7.8E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.120385 | 8.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.059 | 8.5E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.058 | 1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.059 | 1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0587733 | 1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | 0.059 | 1.1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.059 | 1.3E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | 0.059 | 1.3E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.0584915 | 1.3E-12 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg06970472 | chr4:40910981 | APBB2 | -0.035 | 1.5E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.058 | 1.7E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.058 | 1.7E-12 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg07291349 | chr4:40964962 | APBB2 | 0.013 | 1.9E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.058 | 2E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg08016336 | chr4:41181318 | APBB2 | 0.058 | 2E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg16240468 | chr4:40871021 | APBB2 | -0.211123 | 2.3E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0578161 | 2.4E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0577991 | 2.5E-12 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0577717 | 2.5E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | 0.058 | 2.5E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | 0.058 | 2.6E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00132598 | chr4:41016918 | APBB2 | 0.058 | 2.6E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0577153 | 2.6E-12 |
| Kyung WK | 32795589 | DNA methylation | atopy | nasal polyp | discovery | 108 | cg19085693 | chr4:41181104 | APBB2 | 0.035 | 2.8E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.058 | 3E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.057 | 3.2E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg09825105 | chr4:40829726 | APBB2 | -0.358376 | 3.3E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04666705 | chr4:41114510 | APBB2 | 0.057 | 3.9E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.057 | 4.3E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.057 | 4.6E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | -0.0569975 | 4.9E-12 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg08665312 | chr4:41180048 | APBB2 | 0.051 | 4.9E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.057 | 5.1E-12 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg21955154 | chr4:40999951 | APBB2 | -1.560599 | 5.4E-12 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg15989892 | chr4:41063747 | APBB2 | 0.0016 | 6.3E-12 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg15832405 | chr4:41216869 | APBB2 | 0.014 | 6.6E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.057 | 6.7E-12 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg24656517 | chr4:40844307 | APBB2 | 0.021 | 7.5E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg25886371 | chr4:40917710 | APBB2 | -0.239986 | 7.6E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.056 | 7.7E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg02109167 | chr4:41187789 | APBB2 | 0.056 | 7.9E-12 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0563127 | 8.8E-12 |
| Marttila S | 25888029 | DNA methylation | Age group | Peripheral blood mononuclear cells | - | 143 | cg22913249 | chr4:41215979 | APBB2 | 0.9 | 8.9E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.056 | 9.6E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.056 | 9.9E-12 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg13690063 | chr4:40921171 | APBB2 | -0.021 | 1E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.061 | 1E-11 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg13978856 | chr4:40918191 | APBB2 | NA | 1E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg22913249 | chr4:41215979 | APBB2 | 0.16 | 1.1E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg02109167 | chr4:41187789 | APBB2 | 0.056 | 1.1E-11 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | -0.0557924 | 1.4E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | -0.055749 | 1.4E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.056 | 1.4E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.056 | 1.5E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.055663 | 1.5E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.055 | 1.8E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg08665312 | chr4:41180048 | APBB2 | -0.0024 | 1.9E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.055 | 1.9E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0553035 | 2E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg12030017 | chr4:40893064 | APBB2 | -0.0552568 | 2.1E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg09616640 | chr4:41216812 | APBB2 | 0.00048 | 2.4E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.055 | 2.5E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.077 | 2.5E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.055 | 3.2E-11 |
| Kyung WK | 32795589 | DNA methylation | eosinophilia | nasal polyp | discovery | 129 | cg04523623 | chr4:41000965 | APBB2 | 0.033 | 3.3E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg17699214 | chr4:40890013 | APBB2 | 0.00073 | 3.4E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | 0.055 | 3.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.055 | 3.8E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.054 | 4E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0589941 | 4.2E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04666705 | chr4:41114510 | APBB2 | 0.054 | 4.2E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg18630806 | chr4:40862304 | APBB2 | 0.054 | 4.2E-11 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg06485940 | chr4:40859293 | APBB2 | 0.016 | 4.2E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.054 | 4.4E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0543005 | 4.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0541651 | 5.2E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0540501 | 5.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | 0.054 | 5.8E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0539953 | 6E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg06140237 | chr4:41191243 | APBB2 | -0.185538 | 6E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg01954188 | chr4:41216800 | APBB2 | 0.0013 | 6.5E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg06970472 | chr4:40910981 | APBB2 | -0.195183 | 6.6E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.054 | 6.9E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.054 | 7.1E-11 |
| Kyung WK | 32795589 | DNA methylation | atopy | nasal polyp | discovery | 108 | cg02109167 | chr4:41187789 | APBB2 | 0.045 | 8E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg22179055 | chr4:41207235 | APBB2 | 0.054 | 8.3E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | -0.053525 | 8.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.053 | 9.4E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.053 | 9.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.106834 | 1.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg14464517 | chr4:41115076 | APBB2 | 0.053 | 1.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg16708538 | chr4:41011498 | APBB2 | 0.053 | 1.3E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg05020685 | chr4:40858965 | APBB2 | 0.0016 | 1.4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.053 | 1.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | -0.0525269 | 1.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | -0.0524759 | 2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg02696415 | chr4:40994566 | APBB2 | 0.053 | 2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.052 | 2.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.052 | 2.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0522352 | 2.4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | -0.0521586 | 2.6E-10 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg08665312 | chr4:41180048 | APBB2 | NA | 2.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.102568 | 2.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.052 | 3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 4 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.085 | 3.1E-10 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg13812971 | chr4:40876725 | APBB2 | -0.01381 | 3.1E-10 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg04917391 | chr4:40859259 | APBB2 | -1.821808 | 3.2E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg19542542 | chr4:41157025 | APBB2 | 0.00075 | 3.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0518353 | 3.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | -0.0517581 | 3.5E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.071 | 3.5E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.105785 | 3.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0517181 | 3.7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.052 | 3.7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0766981 | 3.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0513113 | 5E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0512082 | 5.4E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg24541457 | chr4:41217717 | APBB2 | 0.0013 | 6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg02696415 | chr4:40994566 | APBB2 | 0.051 | 6.1E-10 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg22718729 | chr4:41216034 | APBB2 | 0.0064 | 6.5E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.051 | 6.5E-10 |
| Marttila S | 25888029 | DNA methylation | Age group | Peripheral blood mononuclear cells | - | 143 | cg04494059 | chr4:40818170 | APBB2 | -0.88830977 | 6.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg03153515 | chr4:41016609 | APBB2 | 0.051 | 6.7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.104592 | 6.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.051 | 6.9E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg08174482 | chr4:40823896 | APBB2 | 0.0048 | 7.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.051 | 7.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.051 | 7.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0508051 | 7.4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0507769 | 7.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg26634049 | chr4:41126855 | APBB2 | 0.051 | 8E-10 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg13978856 | chr4:40918191 | APBB2 | -0.287997 | 8.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0506313 | 8.5E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.051 | 8.7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg02696415 | chr4:40994566 | APBB2 | 0.051 | 8.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.051 | 9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | -0.05054 | 9.1E-10 |
| Kyung WK | 32795589 | DNA methylation | eosinophilia | nasal polyp | discovery | 129 | cg26244738 | chr4:40859344 | APBB2 | 0.022 | 1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.05 | 1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.05 | 1.1E-09 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg22913249 | chr4:41215979 | APBB2 | 3.5 | 1.1E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg25886371 | chr4:40917710 | APBB2 | -0.212896 | 1.1E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg15989892 | chr4:41063747 | APBB2 | -0.185579 | 1.1E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg11398467 | chr4:40829790 | APBB2 | -0.325174 | 1.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0502198 | 1.2E-09 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg15832405 | chr4:41216869 | APBB2 | 0.011 | 1.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.103394 | 1.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.05 | 1.3E-09 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg18526270 | chr4:41216855 | APBB2 | 0.0094 | 1.4E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg25910494 | chr4:40958114 | APBB2 | 0.0015 | 1.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | 0.05 | 1.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.05 | 1.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0497635 | 1.6E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg09277762 | chr4:41030552 | APBB2 | 0.21 | 1.7E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg25333257 | chr4:41217803 | APBB2 | 0.00072 | 1.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.05 | 1.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.05 | 1.7E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg08350742 | chr4:40814531 | APBB2 | 0.18 | 1.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.100304 | 1.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.05 | 1.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0946485 | 1.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.05 | 1.9E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg23968551 | chr4:40818214 | APBB2 | -0.013 | 2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.049 | 2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | -0.0494695 | 2E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg01058879 | chr4:40823935 | APBB2 | 0.0042 | 2.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.049 | 2.1E-09 |
| Marttila S | 25888029 | DNA methylation | Age group | Peripheral blood mononuclear cells | - | 143 | cg05020685 | chr4:40858965 | APBB2 | 0.56 | 2.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | 0.049 | 2.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.049 | 2.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.049 | 2.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.049 | 2.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.049 | 2.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0729229 | 2.4E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg15989892 | chr4:41063747 | APBB2 | 0.18 | 2.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg04666705 | chr4:41114510 | APBB2 | 0.049 | 2.5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.049 | 2.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg11945554 | chr4:40857255 | APBB2 | 0.049 | 2.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 2 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.069 | 2.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0491179 | 2.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0491092 | 2.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | 0.049 | 2.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | -0.0489729 | 2.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0489697 | 2.9E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg14925343 | chr4:41130621 | APBB2 | -0.241384 | 3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.048914 | 3.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.049 | 3.1E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg23884217 | chr4:41147318 | APBB2 | 0.0062 | 3.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.049 | 3.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.049 | 3.5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0487187 | 3.5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.049 | 3.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.049 | 3.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0928385 | 4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0485355 | 4.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg18630806 | chr4:40862304 | APBB2 | 0.048 | 4.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0483428 | 4.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0527505 | 4.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.048 | 4.8E-09 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg22913249 | chr4:41215979 | APBB2 | 0.023 | 4.9E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg22648864 | chr4:40996373 | APBB2 | -0.29114 | 4.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.048 | 5.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0481759 | 5.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg03153515 | chr4:41016609 | APBB2 | -0.0481344 | 5.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.056 | 5.5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg14309469 | chr4:40817953 | APBB2 | 0.048 | 5.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.048 | 5.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | -0.0480224 | 5.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0953124 | 5.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 2 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0496211 | 6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.048 | 6.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0954086 | 6.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0479703 | 6.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.048 | 6.5E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg22648864 | chr4:40996373 | APBB2 | -0.287864 | 6.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0478295 | 6.8E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg22913249 | chr4:41215979 | APBB2 | 0.00013 | 6.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | 0.048 | 6.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.052 | 7.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 3 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0492677 | 7.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0477279 | 7.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.048 | 7.4E-09 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg07291349 | chr4:40964962 | APBB2 | -0.08474 | 7.5E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg20080580 | chr4:41172024 | APBB2 | -0.0017 | 8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0475341 | 8.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | -0.0475085 | 8.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | 0.047 | 8.8E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg16240468 | chr4:40871021 | APBB2 | -0.173512 | 8.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 3 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.066 | 8.9E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg06970472 | chr4:40910981 | APBB2 | -0.171388 | 8.9E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg08016336 | chr4:41181318 | APBB2 | -0.321036 | 9.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0473396 | 9.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | 0.047 | 9.9E-09 |
| Kyung WK | 32795589 | DNA methylation | eosinophilia | nasal polyp | discovery | 129 | cg04917391 | chr4:40859259 | APBB2 | 0.05 | 1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0893165 | 1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.047 | 1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.047 | 1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg13978856 | chr4:40918191 | APBB2 | -0.0567702 | 1.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.047 | 1.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.047 | 1.1E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg01921140 | chr4:40872363 | APBB2 | -0.244449 | 1.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | 0.047 | 1.2E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg01322290 | chr4:40818120 | APBB2 | -0.03385 | 1.2E-08 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg23968551 | chr4:40818214 | APBB2 | 0.023 | 1.2E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg27495108 | chr4:41216882 | APBB2 | 0.00039 | 1.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg02696415 | chr4:40994566 | APBB2 | 0.056 | 1.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0469929 | 1.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.047 | 1.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.047 | 1.3E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg24541457 | chr4:41217717 | APBB2 | -0.001 | 1.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | -0.0468262 | 1.4E-08 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg23884217 | chr4:41147318 | APBB2 | -1.9 | 1.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0467038 | 1.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.047 | 1.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.047 | 1.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.046551 | 1.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.046526 | 1.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.0560809 | 1.7E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg26634049 | chr4:41126855 | APBB2 | -0.189916 | 1.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0464845 | 1.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.046 | 1.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg24782083 | chr4:41198939 | APBB2 | 0.046 | 1.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0464273 | 1.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.046 | 1.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.046403 | 1.9E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg16547382 | chr4:40863050 | APBB2 | -0.0015 | 1.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0463394 | 2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.046 | 2E-08 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent COPD (Self-report) | Whole blood | Basic model | 18078 | cg25186248 | chr4:40814675 | APBB2 | -0.083 | 2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0627315 | 2.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.046 | 2.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.046 | 2.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 2 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.058 | 2.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0461679 | 2.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.046 | 2.2E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg13690063 | chr4:40921171 | APBB2 | 0.0054 | 2.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 2 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.058 | 2.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg11520308 | chr4:40861148 | APBB2 | -0.0460526 | 2.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.046 | 2.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0460004 | 2.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.046 | 2.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 4 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.084 | 2.6E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01465102 | chr4:40942131 | APBB2 | -0.00057 | 2.6E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg11945554 | chr4:40857255 | APBB2 | -0.216112 | 2.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.046 | 2.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | 0.046 | 2.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg20603080 | chr4:40872066 | APBB2 | 0.046 | 2.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.046 | 2.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0458245 | 2.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.046 | 2.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0458005 | 2.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.046 | 3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg14464517 | chr4:41115076 | APBB2 | 0.046 | 3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.046 | 3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.062 | 3.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.046 | 3.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.046 | 3.2E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg09277762 | chr4:41030552 | APBB2 | -0.198207 | 3.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg08665312 | chr4:41180048 | APBB2 | 0.046 | 3.2E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg11520308 | chr4:40861148 | APBB2 | 0.15 | 3.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0457462 | 3.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | -0.0455882 | 3.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | 0.046 | 3.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | 0.045 | 3.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.045 | 3.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg16708538 | chr4:41011498 | APBB2 | 0.045 | 3.9E-08 |
| Kyung WK | 32795589 | DNA methylation | atopy | nasal polyp | discovery | 108 | cg27514091 | chr4:41079821 | APBB2 | 0.023 | 3.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | 0.045 | 4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.045 | 4.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.045 | 4.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg12030017 | chr4:40893064 | APBB2 | -0.045155 | 4.5E-08 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Basic model | 17749 | cg06970472 | chr4:40910981 | APBB2 | -0.032 | 4.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg00132598 | chr4:41016918 | APBB2 | 0.045 | 4.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | 0.045 | 4.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.063 | 4.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.063 | 4.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.045 | 4.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0450162 | 4.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0525353 | 5.1E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg22913249 | chr4:41215979 | APBB2 | 0.12 | 5.1E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg12616125 | chr4:41216508 | APBB2 | 0.0004 | 5.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg14925343 | chr4:41130621 | APBB2 | 0.045 | 5.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | 0.045 | 5.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.045 | 5.7E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg22179055 | chr4:41207235 | APBB2 | 0.0036 | 5.7E-08 |
| Sayols-Baixeras S | 29099282 | Body mass index | DNA methylation | Whole blood | Meta-analysis model 2 | 3156 | cg23884217 | chr4:41147318 | APBB2 | -0.85 | 5.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | 0.045 | 5.7E-08 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg24644605 | chr4:40944984 | APBB2 | -1.6 | 5.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 1 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0447547 | 5.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.045 | 6E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg18526270 | chr4:41216855 | APBB2 | 0.0003 | 6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04523623 | chr4:41000965 | APBB2 | -0.0446383 | 6.3E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg04494059 | chr4:40818170 | APBB2 | -0.198866 | 6.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0446242 | 6.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg22179055 | chr4:41207235 | APBB2 | 0.045 | 6.4E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg24656517 | chr4:40844307 | APBB2 | -0.00057 | 6.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.045 | 6.6E-08 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg05894734 | chr4:40859249 | APBB2 | 0.006 | 6.8E-08 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg15989892 | chr4:41063747 | APBB2 | -1.3 | 7.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | -0.0444327 | 7.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0444286 | 7.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.044 | 7.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.044 | 7.4E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg04568895 | chr4:41145263 | APBB2 | -0.198942 | 7.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg02109167 | chr4:41187789 | APBB2 | 0.044 | 7.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg08191405 | chr4:40871657 | APBB2 | 0.044 | 7.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 3 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.075 | 7.6E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg23884217 | chr4:41147318 | APBB2 | 0.25 | 7.8E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | sensitivity | 18225 | cg08350742 | chr4:40814531 | APBB2 | 0.18 | 7.8E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg11382761 | chr4:41031037 | APBB2 | -0.01314 | 8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0442915 | 8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0442751 | 8.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.044 | 8.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0554004 | 8.3E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg26244738 | chr4:40859344 | APBB2 | 0.00043 | 8.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 3 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0442687 | 8.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.0441809 | 8.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH35 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0441777 | 8.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg14464517 | chr4:41115076 | APBB2 | -0.0441398 | 8.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.044 | 8.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | 0.044 | 9.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.0440076 | 9.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 4 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.072 | 9.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0439641 | 1E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg21593628 | chr4:40890812 | APBB2 | -0.0083 | 1E-07 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg21330088 | chr4:41198045 | APBB2 | -1.472428 | 1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.044 | 1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 2 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.074 | 1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.044 | 1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.044 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | -0.0438754 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | -0.0438301 | 1.1E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg11404380 | chr4:41215359 | APBB2 | 0.001 | 1.1E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg26865481 | chr4:41206196 | APBB2 | 0.00085 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0438114 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg14925343 | chr4:41130621 | APBB2 | 0.044 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.044 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.044 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0437347 | 1.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg14464517 | chr4:41115076 | APBB2 | 0.044 | 1.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | 0.044 | 1.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH25 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0435059 | 1.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | 0.043 | 1.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.043 | 1.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | -0.0434612 | 1.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.043 | 1.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg21956384 | chr4:41191857 | APBB2 | 0.043 | 1.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.043 | 1.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.043 | 1.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0432954 | 1.6E-07 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg14290210 | chr4:41162942 | APBB2 | -0.02695 | 1.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | 0.043 | 1.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0833707 | 1.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | 0.043 | 1.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0859555 | 1.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg02109167 | chr4:41187789 | APBB2 | 0.043 | 1.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.043 | 1.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.043 | 1.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 3 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.054 | 1.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | -0.0430851 | 1.8E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg04494059 | chr4:40818170 | APBB2 | 0.00073 | 1.8E-07 |
| Anna Ulrich | 38184627 | DNA methylation | Idiopathic/heritable pulmonary arterial hypertension | whole blood | Discovery | 1655 | cg25486993 | chr4:40920526 | APBB2 | -26.0 | 1.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.058 | 1.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0430453 | 1.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.043 | 1.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0429729 | 1.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0429454 | 2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0429181 | 2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | 0.043 | 2E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg14290210 | chr4:41162942 | APBB2 | 0.0019 | 2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.059 | 2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 3 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0440639 | 2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.043 | 2.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.043 | 2.2E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg12455762 | chr4:40859095 | APBB2 | 0.00045 | 2.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | 0.043 | 2.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0J9YX35 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0426421 | 2.4E-07 |
| Inkster A | 34044884 | DNA methylation | Sex | Placenta | Discovery | 585 | cg11404380 | chr4:41215359 | APBB2 | 6.6 | 2.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg16240468 | chr4:40871021 | APBB2 | 0.048 | 2.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg06473827 | chr4:41209874 | APBB2 | 0.043 | 2.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg11267549 | chr4:41149137 | APBB2 | -0.0425996 | 2.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.053 | 2.5E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg06970472 | chr4:40910981 | APBB2 | 0.0012 | 2.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0424956 | 2.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0424754 | 2.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | -0.0424628 | 2.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O43866 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0424477 | 2.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.042 | 2.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0463036 | 2.9E-07 |
| Singmann P | 26500701 | DNA methylation | Sex | Whole blood | KORA F4 | 1799 | cg27434086 | chr4:41218082 | APBB2 | NA | 2.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0436707 | 3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B7B8 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0423036 | 3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.042 | 3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0422301 | 3.1E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg15989892 | chr4:41063747 | APBB2 | -0.155182 | 3.3E-07 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg11382761 | chr4:41031037 | APBB2 | -0.0088 | 3.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0872265 | 3.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0421005 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.058 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.042 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg16552881 | chr4:40839375 | APBB2 | 0.042 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0420678 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | -0.0420561 | 3.5E-07 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Previous week consumption discovery | 5606 | cg06970472 | chr4:40910981 | APBB2 | NA | 3.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg16240468 | chr4:40871021 | APBB2 | 0.048 | 3.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | 0.042 | 3.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0807004 | 3.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg16708538 | chr4:41011498 | APBB2 | 0.042 | 3.6E-07 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg14925343 | chr4:41130621 | APBB2 | -2.0 | 3.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0419773 | 3.7E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg19542542 | chr4:41157025 | APBB2 | -0.0005 | 3.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.042 | 3.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 3 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.052 | 3.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.042 | 3.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0836092 | 4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0418221 | 4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.042 | 4.1E-07 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg12616125 | chr4:41216508 | APBB2 | 0.0068 | 4.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg16547382 | chr4:40863050 | APBB2 | 0.042 | 4.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 2 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0585712 | 4.1E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg14464517 | chr4:41115076 | APBB2 | -0.156599 | 4.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.042 | 4.3E-07 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg25186248 | chr4:40814675 | APBB2 | -2.6 | 4.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.042 | 4.4E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg22179055 | chr4:41207235 | APBB2 | -0.004 | 4.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 3 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0429542 | 4.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 4 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.068 | 4.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.042 | 4.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0847096 | 4.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0795196 | 4.7E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg05020685 | chr4:40858965 | APBB2 | 0.15 | 4.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.042 | 4.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg16552881 | chr4:40839375 | APBB2 | 0.041 | 5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.041478 | 5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg22179055 | chr4:41207235 | APBB2 | 0.041 | 5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0516082 | 5.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.041 | 5.3E-07 |
| Battram T | 27886173 | DNA methylation | Ulcerative colitis | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 | 163 | cg25910494 | chr4:40958114 | APBB2 | 0.022 | 5.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.041 | 5.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0413383 | 5.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.041 | 5.5E-07 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg25186248 | chr4:40814675 | APBB2 | -0.042 | 5.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0412621 | 5.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | -0.0411343 | 6.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0411093 | 6.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.041 | 6.4E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg01322290 | chr4:40818120 | APBB2 | -0.011 | 6.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg11520308 | chr4:40861148 | APBB2 | -0.0414386 | 6.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | -0.0410319 | 6.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 3 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.043 | 6.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0409912 | 6.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0409841 | 6.8E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg04917391 | chr4:40859259 | APBB2 | 0.0006 | 6.9E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg05057585 | chr4:41213424 | APBB2 | 0.0071 | 7.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 2 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.043 | 7.2E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg24992745 | chr4:41215654 | APBB2 | 0.00052 | 7.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.041 | 7.3E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg01465102 | chr4:40942131 | APBB2 | -0.17847 | 7.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0408409 | 7.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg00132598 | chr4:41016918 | APBB2 | 0.041 | 7.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg15989892 | chr4:41063747 | APBB2 | -0.0505105 | 7.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B7B8 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0407449 | 7.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 1 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0407099 | 8.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.041 | 8.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0407045 | 8.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0677511 | 8.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 2 | 14671 | cg23802782 | chr4:41188838 | APBB2 | -0.0426035 | 8.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.041 | 8.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0406188 | 8.6E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg15563027 | chr4:41215455 | APBB2 | 0.0058 | 8.6E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg23884217 | chr4:41147318 | APBB2 | -0.233113 | 8.6E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg25333257 | chr4:41217803 | APBB2 | -0.0042 | 8.7E-07 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg02109167 | chr4:41187789 | APBB2 | -0.028 | 8.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | -0.0405766 | 8.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.041 | 8.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 4 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.058 | 9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg14309469 | chr4:40817953 | APBB2 | 0.041 | 9.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.041 | 9.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | -0.0404619 | 9.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | -0.0404203 | 9.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | 0.04 | 9.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0404058 | 9.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0410525 | 9.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0403984 | 9.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 3 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0416949 | 9.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0403866 | 9.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 2 | 14671 | cg02696415 | chr4:40994566 | APBB2 | 0.042 | 9.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.04 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg03153515 | chr4:41016609 | APBB2 | 0.04 | 1E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg24541457 | chr4:41217717 | APBB2 | 0.01 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 3 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0406355 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg21956384 | chr4:41191857 | APBB2 | -0.0403273 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg23832889 | chr4:41048727 | APBB2 | 0.04 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0403139 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH36 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0402749 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0431536 | 1.1E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg04666705 | chr4:41114510 | APBB2 | -0.186189 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg04673478 | chr4:41124815 | APBB2 | 0.04 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0402238 | 1.1E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg25910494 | chr4:40958114 | APBB2 | -0.00067 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.04 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.04 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.044 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.04 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | -0.0400544 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0400523 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0400389 | 1.2E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | sensitivity | 18270 | cg07291349 | chr4:40964962 | APBB2 | -0.169197 | 1.2E-06 |
| Reynolds LM | 25404168 | DNA methylation | Age | T cells | T cells | 227 | cg05020685 | chr4:40858965 | APBB2 | NA | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg19085693 | chr4:41181104 | APBB2 | 0.04 | 1.3E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | discovery | 18270 | cg24992745 | chr4:41215654 | APBB2 | -0.144568 | 1.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0399369 | 1.3E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | discovery | 18270 | cg07291349 | chr4:40964962 | APBB2 | -0.152446 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.04 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0398653 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.04 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg11520308 | chr4:40861148 | APBB2 | -0.0399528 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | 0.04 | 1.4E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg15894947 | chr4:40824085 | APBB2 | -0.152021 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg11267549 | chr4:41149137 | APBB2 | 0.04 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg11267549 | chr4:41149137 | APBB2 | 0.04 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 3 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.048 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0434493 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.04 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.04 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.04 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.04 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | 0.04 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.074 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.055 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | 0.04 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg27434086 | chr4:41218082 | APBB2 | -0.0396454 | 1.6E-06 |
| Singmann P | 26500701 | DNA methylation | Sex | Whole blood | KORA F4 | 1799 | cg16552881 | chr4:40839375 | APBB2 | NA | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 4 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0727228 | 1.6E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg26865481 | chr4:41206196 | APBB2 | 0.0029 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.04 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0395672 | 1.6E-06 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg05020685 | chr4:40858965 | APBB2 | 1.2 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0399861 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0395406 | 1.7E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | sensitivity | 18270 | cg11267549 | chr4:41149137 | APBB2 | -0.115918 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg17699214 | chr4:40890013 | APBB2 | 0.04 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | -0.039496 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 4 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0836362 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg23802782 | chr4:41188838 | APBB2 | 0.039 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0795535 | 1.7E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg24644605 | chr4:40944984 | APBB2 | -0.1752 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0394339 | 1.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0394316 | 1.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg16240468 | chr4:40871021 | APBB2 | -0.0449259 | 1.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg17775987 | chr4:40991374 | APBB2 | 0.04 | 1.8E-06 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Fully-adjusted model | 14040 | cg07291349 | chr4:40964962 | APBB2 | 1.2 | 1.8E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg04666705 | chr4:41114510 | APBB2 | -0.032 | 1.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 2 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0407038 | 1.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0393364 | 1.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg00047667 | chr4:41202562 | APBB2 | 0.039 | 1.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.049 | 1.9E-06 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Fully-adjusted model | 14040 | cg08350742 | chr4:40814531 | APBB2 | -0.96 | 1.9E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg27514091 | chr4:41079821 | APBB2 | -0.126165 | 1.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | 0.039 | 1.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg17699214 | chr4:40890013 | APBB2 | 0.04 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P19652 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.039 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | -0.0392346 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg25593834 | chr4:40824632 | APBB2 | 0.039 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | -0.039202 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg20603080 | chr4:40872066 | APBB2 | 0.039 | 2.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.039 | 2.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg14925343 | chr4:41130621 | APBB2 | 0.039 | 2.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.039 | 2.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0390933 | 2.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.039 | 2.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg04666705 | chr4:41114510 | APBB2 | 0.039 | 2.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.039 | 2.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg02696415 | chr4:40994566 | APBB2 | 0.039 | 2.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg22648864 | chr4:40996373 | APBB2 | -0.0494547 | 2.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0528143 | 2.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg06473827 | chr4:41209874 | APBB2 | 0.039 | 2.3E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg27434086 | chr4:41218082 | APBB2 | 0.16 | 2.3E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg03870448 | chr4:41214687 | APBB2 | 0.0072 | 2.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.039 | 2.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0389668 | 2.3E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg13690063 | chr4:40921171 | APBB2 | -0.174403 | 2.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 3 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0428283 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg04568895 | chr4:41145263 | APBB2 | -0.0389366 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 3 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0372339 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg04673478 | chr4:41124815 | APBB2 | 0.039 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.039 | 2.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | 0.039 | 2.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 2 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0489655 | 2.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg00132598 | chr4:41016918 | APBB2 | 0.039 | 2.5E-06 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg01322290 | chr4:40818120 | APBB2 | 0.015 | 2.5E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg25186248 | chr4:40814675 | APBB2 | 0.22 | 2.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0388035 | 2.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0768463 | 2.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 4 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0535156 | 2.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg21956384 | chr4:41191857 | APBB2 | 0.039 | 2.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0399817 | 2.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 2 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0391495 | 2.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.0466148 | 2.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg11945554 | chr4:40857255 | APBB2 | 0.039 | 2.8E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg03147663 | chr4:40823362 | APBB2 | -0.00927 | 2.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | 0.039 | 2.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg04673478 | chr4:41124815 | APBB2 | -0.0385922 | 2.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | -0.0385577 | 3E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Basic model | 17749 | cg25886371 | chr4:40917710 | APBB2 | -0.033 | 3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.039 | 3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg04666705 | chr4:41114510 | APBB2 | 0.039 | 3.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0385113 | 3.1E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Basic model | 17749 | cg09277762 | chr4:41030552 | APBB2 | -0.034 | 3.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0570359 | 3.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q15848 | whole blood | OSCA model 2 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.043 | 3.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0448523 | 3.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0384537 | 3.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg12030017 | chr4:40893064 | APBB2 | -0.038449 | 3.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0384299 | 3.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg00132598 | chr4:41016918 | APBB2 | -0.0383764 | 3.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.038373 | 3.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg08016336 | chr4:41181318 | APBB2 | -0.0383675 | 3.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0383622 | 3.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg20603080 | chr4:40872066 | APBB2 | 0.038 | 3.4E-06 |
| Gadd DA | 35945220 | TFF3 protein levels (SeqId = 4721-54) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 1.1 | 3.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg13978856 | chr4:40918191 | APBB2 | -0.0460831 | 3.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.038 | 3.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg14925343 | chr4:41130621 | APBB2 | 0.038 | 3.5E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg15832405 | chr4:41216869 | APBB2 | 0.00021 | 3.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 4 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0465908 | 3.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.038 | 3.6E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg06140237 | chr4:41191243 | APBB2 | -0.131336 | 3.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg06473827 | chr4:41209874 | APBB2 | 0.038 | 3.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg11520308 | chr4:40861148 | APBB2 | 0.038 | 3.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.042 | 3.7E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg15989892 | chr4:41063747 | APBB2 | 0.0049 | 3.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.05369 | 3.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0381464 | 3.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 4 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.0554108 | 3.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0381232 | 3.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | -0.0381115 | 3.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.038 | 3.9E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg02650667 | chr4:41072974 | APBB2 | -0.0095 | 4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 2 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0535471 | 4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.038 | 4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | -0.0380472 | 4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 3 | 14671 | cg02696415 | chr4:40994566 | APBB2 | 0.039 | 4.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg22913249 | chr4:41215979 | APBB2 | 0.038 | 4.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | -0.0379832 | 4.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.038 | 4.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0379576 | 4.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 4 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.07267 | 4.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg09277762 | chr4:41030552 | APBB2 | -0.043868 | 4.3E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent Type 2 Diabetes (Self-report) | Whole blood | Basic model | 18005 | cg06970472 | chr4:40910981 | APBB2 | -0.06 | 4.3E-06 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg21593628 | chr4:40890812 | APBB2 | 0.011 | 4.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.038 | 4.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0378991 | 4.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | -0.0378984 | 4.4E-06 |
| Kashima K | 33564054 | DNA methylation | gestational age | Cord blood | None | 110 | cg06970472 | chr4:40910981 | APBB2 | 0.0043 | 4.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg05020685 | chr4:40858965 | APBB2 | 0.04 | 4.4E-06 |
| Gadd DA | 35945220 | GZMK protein levels (SeqId = 9545-156) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23884217 | chr4:41147318 | APBB2 | -1.13 | 4.5E-06 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Fully-adjusted model | 14040 | cg02774791 | chr4:41098192 | APBB2 | 1.4 | 4.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | 0.038 | 4.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg08016336 | chr4:41181318 | APBB2 | 0.038 | 4.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.038 | 4.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.038 | 4.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg26947966 | chr4:40939389 | APBB2 | 0.038 | 4.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg04523623 | chr4:41000965 | APBB2 | 0.038 | 4.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg26634049 | chr4:41126855 | APBB2 | -0.0377507 | 4.8E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg18939200 | chr4:40814466 | APBB2 | 0.27 | 4.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 4 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0559514 | 4.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 4 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.056953 | 4.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.038 | 5E-06 |
| Gross AM | 27105112 | DNA methylation | HIV infection | CD4+ T-cells | CD4+ T-cells | 60 | cg06970472 | chr4:40910981 | APBB2 | -0.385032 | 5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.038 | 5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.038 | 5.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | -0.0376156 | 5.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.062714 | 5.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg25886371 | chr4:40917710 | APBB2 | -0.0465383 | 5.2E-06 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg02694037 | chr4:41125894 | APBB2 | 0.012 | 5.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0375964 | 5.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | 0.038 | 5.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.038 | 5.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 2 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.078 | 5.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | 0.038 | 5.4E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg06140237 | chr4:41191243 | APBB2 | 0.13 | 5.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | 0.037 | 5.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P20851 | whole blood | OSCA model 4 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0569132 | 5.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | -0.0374681 | 5.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0374564 | 5.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | -0.0374555 | 5.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg11945554 | chr4:40857255 | APBB2 | 0.037 | 5.7E-06 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg16240468 | chr4:40871021 | APBB2 | -1.2 | 5.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.037406 | 5.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P19652 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0373923 | 5.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.037 | 5.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.037 | 5.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg16708538 | chr4:41011498 | APBB2 | 0.037 | 6E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg02109167 | chr4:41187789 | APBB2 | -0.148161 | 6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0373441 | 6.1E-06 |
| Gadd DA | 35945220 | LILRA5 protein levels (SeqId = 8766-29) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 1.0 | 6.1E-06 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg14464517 | chr4:41115076 | APBB2 | -0.1245318 | 6.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH36 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0373048 | 6.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 3 | 14671 | cg17699214 | chr4:40890013 | APBB2 | 0.036 | 6.2E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg01390277 | chr4:40827593 | APBB2 | -0.245009 | 6.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0372949 | 6.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.054 | 6.3E-06 |
| Gadd DA | 35945220 | FLRT2 protein levels (SeqId = 13122-19) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 1.0 | 6.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P19652 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.037 | 6.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.037 | 6.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 3 | 14671 | cg17699214 | chr4:40890013 | APBB2 | 0.037 | 6.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.037 | 6.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 3 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.077 | 6.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.041 | 6.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.037 | 6.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.077 | 6.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg08016336 | chr4:41181318 | APBB2 | -0.0371341 | 6.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | -0.0370866 | 7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg14925343 | chr4:41130621 | APBB2 | -0.0370828 | 7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0370583 | 7.1E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | discovery | 18270 | cg11267549 | chr4:41149137 | APBB2 | -0.0996453 | 7.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | 0.037 | 7.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.037 | 7.2E-06 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg23968551 | chr4:40818214 | APBB2 | 0.015 | 7.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.037 | 7.3E-06 |
| Kashima K | 33564054 | DNA methylation | gestational age | Cord blood | None | 110 | cg23884217 | chr4:41147318 | APBB2 | -0.0024 | 7.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.046 | 7.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0369963 | 7.4E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01954188 | chr4:41216800 | APBB2 | 0.00072 | 7.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.037 | 7.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg18630806 | chr4:40862304 | APBB2 | 0.037 | 7.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | 0.037 | 7.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.037 | 7.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH36 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0369052 | 7.8E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg13690063 | chr4:40921171 | APBB2 | -0.0056 | 7.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.036862 | 8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.037 | 8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg01322290 | chr4:40818120 | APBB2 | 0.037 | 8.1E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg22179055 | chr4:41207235 | APBB2 | 0.015 | 8.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 3 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0618822 | 8.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0367531 | 8.5E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg02379560 | chr4:40859280 | APBB2 | 0.0089 | 8.5E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg26634049 | chr4:41126855 | APBB2 | 0.15 | 8.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.037 | 8.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0513454 | 8.8E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg02694037 | chr4:41125894 | APBB2 | -0.0079 | 9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.037 | 9.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.037 | 9.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | -0.0366245 | 9.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.051 | 9.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.051 | 9.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | -0.0365747 | 9.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0365665 | 9.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 3 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.076 | 9.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.037 | 9.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.053 | 9.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg01465102 | chr4:40942131 | APBB2 | -0.0376256 | 9.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0397654 | 9.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | 0.037 | 9.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg02696415 | chr4:40994566 | APBB2 | 0.037 | 9.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.049 | 9.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.036 | 9.8E-06 |
| Kashima K | 33564054 | DNA methylation | gestational age | Cord blood | None | 110 | cg24644605 | chr4:40944984 | APBB2 | -0.0024 | 9.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg26947966 | chr4:40939389 | APBB2 | -0.0364774 | 9.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.036 | 1E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Basic model | 17749 | cg06140237 | chr4:41191243 | APBB2 | -0.026 | 1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg16552881 | chr4:40839375 | APBB2 | 0.036 | 1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | -0.0363689 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 2 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0616103 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg02109167 | chr4:41187789 | APBB2 | 0.036 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.036 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH25 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | -0.0363065 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 1 | 14671 | cg02696415 | chr4:40994566 | APBB2 | 0.036 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | 0.036 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | -0.036289 | 1.1E-05 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg01465102 | chr4:40942131 | APBB2 | -0.00939 | 1.1E-05 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg14290210 | chr4:41162942 | APBB2 | 0.012 | 1.1E-05 |
| Gadd DA | 35945220 | GNLY protein levels (SeqId = 3195-50) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg09825105 | chr4:40829726 | APBB2 | -1.17 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O14791 | whole blood | OSCA model 2 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0375106 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0691247 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH35 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0362329 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 1 | 14671 | cg14925343 | chr4:41130621 | APBB2 | -0.0362268 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0362765 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0362046 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg22913249 | chr4:41215979 | APBB2 | -0.0361418 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.036 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0360886 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 3 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.036 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0360822 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | -0.036074 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | 0.036 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.036 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg17775987 | chr4:40991374 | APBB2 | 0.036 | 1.2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg17775987 | chr4:40991374 | APBB2 | -0.196315 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | -0.0360268 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg24656517 | chr4:40844307 | APBB2 | 0.036 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.036 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg14464517 | chr4:41115076 | APBB2 | -0.0395127 | 1.3E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent COPD (Self-report) | Whole blood | Basic model | 18078 | cg18939200 | chr4:40814466 | APBB2 | -0.068 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 3 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.04 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.036 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | 0.036 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.035 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.0358857 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 4 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0576034 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 4 | 14671 | cg11520308 | chr4:40861148 | APBB2 | 0.043 | 1.4E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg05020685 | chr4:40858965 | APBB2 | 2.8 | 1.4E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg12455762 | chr4:40859095 | APBB2 | 0.00051 | 1.4E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg24992745 | chr4:41215654 | APBB2 | 0.00068 | 1.4E-05 |
| Gadd DA | 35945220 | CD59 protein levels (SeqId = 11514-196) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 0.99 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 3 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.035 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 4 | 14671 | cg04666705 | chr4:41114510 | APBB2 | -0.0432465 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0358319 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | -0.0358231 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 3 | 14671 | cg23802782 | chr4:41188838 | APBB2 | -0.0371415 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 2 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.072 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | -0.0358012 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg24656517 | chr4:40844307 | APBB2 | 0.036 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg23802782 | chr4:41188838 | APBB2 | 0.036 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0357791 | 1.5E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg09825105 | chr4:40829726 | APBB2 | -0.222942 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.036 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH35 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0357638 | 1.5E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg09825105 | chr4:40829726 | APBB2 | -0.223557 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.036 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | 0.036 | 1.5E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg08670693 | chr4:41162197 | APBB2 | 0.0004 | 1.5E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg16823610 | chr4:40856529 | APBB2 | 0.002 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | -0.0357146 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0357113 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0357027 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.044 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.036 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.035669 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 2 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0497854 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.036 | 1.6E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg23884217 | chr4:41147318 | APBB2 | -0.203972 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg14464517 | chr4:41115076 | APBB2 | 0.036 | 1.6E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg04666705 | chr4:41114510 | APBB2 | 0.16 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O14791 | whole blood | OSCA model 3 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0367316 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.045 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg18939200 | chr4:40814466 | APBB2 | 0.036 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg23802782 | chr4:41188838 | APBB2 | 0.036 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | -0.0356098 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg05020685 | chr4:40858965 | APBB2 | -0.0378246 | 1.6E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg09277762 | chr4:41030552 | APBB2 | -0.154103 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.0355538 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0355482 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.035546 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.036 | 1.7E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg21955154 | chr4:40999951 | APBB2 | -0.00096 | 1.7E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg23735712 | chr4:40858984 | APBB2 | 0.00012 | 1.7E-05 |
| Kashima K | 33564054 | DNA methylation | gestational age | Cord blood | None | 110 | cg23753351 | chr4:40860327 | APBB2 | -0.0056 | 1.7E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg25886371 | chr4:40917710 | APBB2 | -1.3 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04523623 | chr4:41000965 | APBB2 | -0.0354976 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg27514091 | chr4:41079821 | APBB2 | 0.04 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH25 | whole blood | OSCA model 1 | 14671 | cg22179055 | chr4:41207235 | APBB2 | -0.0354951 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.044 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02760 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.039 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 3 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.039 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0494724 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.035 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.035 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg07862526 | chr4:41104476 | APBB2 | 0.035 | 1.8E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg12455762 | chr4:40859095 | APBB2 | 0.0017 | 1.8E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg22648864 | chr4:40996373 | APBB2 | -1.8 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | -0.0353473 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg27434086 | chr4:41218082 | APBB2 | -0.0360414 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O43866 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0353148 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg26634049 | chr4:41126855 | APBB2 | 0.035 | 1.9E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg26244738 | chr4:40859344 | APBB2 | 0.0018 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg08191405 | chr4:40871657 | APBB2 | 0.035 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.044 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0352657 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.049 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.0352571 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg18630806 | chr4:40862304 | APBB2 | 0.035 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 4 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.052 | 1.9E-05 |
| Hannon E | 27572077 | DNA methylation | Schizophrenia | Whole blood | Phase 1 | 675 | cg22179055 | chr4:41207235 | APBB2 | 0.012 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.035 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O14791 | whole blood | OSCA model 1 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0352123 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.039 | 2E-05 |
| Battram T | None | DNA methylation | Phospholipids to total lipids ratio in very large HDL | Whole blood | None | 678 | cg16364495 | chr4:40859251 | APBB2 | -0.025 | 2E-05 |
| Christiansen C | 33593402 | DNA methylation | Smoking | Whole blood | Current vs never smoking meta-analysis in European samples | 912 | cg23056675 | chr4:40991730 | APBB2 | NA | 2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg10793372 | chr4:40836027 | APBB2 | 0.18 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.035178 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0351774 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | 0.035 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0351494 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.035 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 3 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0476883 | 2.1E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg15989892 | chr4:41063747 | APBB2 | -0.0058 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg12030017 | chr4:40893064 | APBB2 | 0.035 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0351099 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.035 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | 0.035 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | -0.0350875 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | 0.035 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0350577 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg27514091 | chr4:41079821 | APBB2 | -0.0350527 | 2.2E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg20080580 | chr4:41172024 | APBB2 | 0.97 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg09219540 | chr4:40828790 | APBB2 | -0.0350382 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.035 | 2.2E-05 |
| Gadd DA | 35945220 | LY9 protein levels (SeqId = 3324-51) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg06970472 | chr4:40910981 | APBB2 | -0.61 | 2.3E-05 |
| Gadd DA | 35945220 | POR protein levels (SeqId = 2731-29) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg18939200 | chr4:40814466 | APBB2 | -1.08 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg16708538 | chr4:41011498 | APBB2 | 0.035 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg08174482 | chr4:40823896 | APBB2 | 0.035 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg20603080 | chr4:40872066 | APBB2 | 0.035 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 2 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.043 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.047899 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.035 | 2.4E-05 |
| Gadd DA | 35945220 | PAPPA protein levels (SeqId = 4148-49) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg12439416 | chr4:40832685 | APBB2 | -0.66 | 2.4E-05 |
| Gadd DA | 35945220 | RGMA protein levels (SeqId = 5483-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 0.96 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 3 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0488703 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg14464517 | chr4:41115076 | APBB2 | -0.0348495 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg02109167 | chr4:41187789 | APBB2 | 0.035 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg26634049 | chr4:41126855 | APBB2 | 0.035 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | -0.0347568 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 2 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.044 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0J9YX35 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0347413 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.048 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.035 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0346945 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg02696415 | chr4:40994566 | APBB2 | 0.036 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0346742 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | -0.0346717 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | -0.0346556 | 2.7E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg15563027 | chr4:41215455 | APBB2 | 0.0043 | 2.7E-05 |
| Anna Ulrich | 38184627 | DNA methylation | Idiopathic/heritable pulmonary arterial hypertension | whole blood | Discovery | 1655 | cg21955154 | chr4:40999951 | APBB2 | -16.0 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg08016336 | chr4:41181318 | APBB2 | 0.035 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.035 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0346195 | 2.7E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg04673478 | chr4:41124815 | APBB2 | -0.168349 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.035 | 2.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 2 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.048 | 2.8E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg20417855 | chr4:40976320 | APBB2 | -0.0015 | 2.8E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent COPD (Self-report) | Whole blood | Basic model | 18078 | cg05490745 | chr4:40814571 | APBB2 | -0.061 | 2.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg16547382 | chr4:40863050 | APBB2 | 0.035 | 2.8E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg13812971 | chr4:40876725 | APBB2 | -0.158325 | 2.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg09277762 | chr4:41030552 | APBB2 | 0.04 | 2.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0345394 | 2.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg26928483 | chr4:40913105 | APBB2 | -0.185256 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 3 | 14671 | cg01465102 | chr4:40942131 | APBB2 | -0.0353839 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.035 | 2.9E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Basic model | 17749 | cg23884217 | chr4:41147318 | APBB2 | -0.04 | 2.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg11945554 | chr4:40857255 | APBB2 | -0.16271 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0345028 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.035 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0344892 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg22913249 | chr4:41215979 | APBB2 | -0.0344695 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg11520308 | chr4:40861148 | APBB2 | 0.035 | 3E-05 |
| Gadd DA | 35945220 | RGMB protein levels (SeqId = 3331-8) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23681495 | chr4:40982188 | APBB2 | -0.76 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.034 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | -0.0344339 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg01465102 | chr4:40942131 | APBB2 | 0.034 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.034432 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.034 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.041 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0343974 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.041 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.034 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 3 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.069 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 2 | 14671 | cg25886371 | chr4:40917710 | APBB2 | -0.0420216 | 3.1E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg16552881 | chr4:40839375 | APBB2 | -0.00069 | 3.2E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg24656517 | chr4:40844307 | APBB2 | 0.0028 | 3.2E-05 |
| Gadd DA | 35945220 | FSTL1 protein levels (SeqId = 13112-179) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 0.95 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0343185 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01009 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.034 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0342883 | 3.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 3 | 14671 | cg02109167 | chr4:41187789 | APBB2 | 0.034 | 3.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 3 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.032 | 3.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | -0.034265 | 3.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg24644605 | chr4:40944984 | APBB2 | 0.04 | 3.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | -0.0342349 | 3.4E-05 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg08665312 | chr4:41180048 | APBB2 | 0.014 | 3.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.034 | 3.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg08016336 | chr4:41181318 | APBB2 | 0.034 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.034 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01780 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0341634 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0A0MT89 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.03416 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.034 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | -0.0341579 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg04673478 | chr4:41124815 | APBB2 | -0.0341454 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg02109167 | chr4:41187789 | APBB2 | -0.0341388 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg26634049 | chr4:41126855 | APBB2 | 0.034 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0343002 | 3.6E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg15989892 | chr4:41063747 | APBB2 | -0.022 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.042 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg07862526 | chr4:41104476 | APBB2 | 0.034 | 3.6E-05 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg23753351 | chr4:40860327 | APBB2 | -0.00056849 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0340735 | 3.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 3 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.037 | 3.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg26634049 | chr4:41126855 | APBB2 | 0.037 | 3.7E-05 |
| Gadd DA | 35945220 | EPHB2 protein levels (SeqId = 8225-86) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 0.94 | 3.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | -0.0340449 | 3.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.034 | 3.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.046 | 3.8E-05 |
| Gadd DA | 35945220 | EPHB6 protein levels (SeqId = 5078-82) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23681495 | chr4:40982188 | APBB2 | -0.75 | 3.8E-05 |
| Gadd DA | 35945220 | CCNB1IP1 protein levels (SeqId = 9728-4) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg27514091 | chr4:41079821 | APBB2 | 0.59 | 3.8E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Neutrophils | Neutrophils | 60 | cg08174482 | chr4:40823896 | APBB2 | -0.133644 | 3.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.034 | 3.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.034 | 3.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg08350742 | chr4:40814531 | APBB2 | -0.128439 | 3.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.034 | 3.9E-05 |
| Gadd DA | 35945220 | GZMA protein levels (SeqId = 3440-7) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg06970472 | chr4:40910981 | APBB2 | -0.59 | 3.9E-05 |
| Hoang | 34516295 | DNA methylation | 2,4-Dichlorophenoxyacetic acid (2,4-D) | whole blood | discovery | 466 | cg26928483 | chr4:40913105 | APBB2 | -0.00258 | 3.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 2 | 14671 | cg01390277 | chr4:40827593 | APBB2 | -0.0489302 | 3.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.034 | 3.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg27514091 | chr4:41079821 | APBB2 | -0.108707 | 4E-05 |
| Gadd DA | 35945220 | CLEC3B protein levels (SeqId = 5701-81) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23753351 | chr4:40860327 | APBB2 | -0.58 | 4.2E-05 |
| Gadd DA | 35945220 | AXIN2 protein levels (SeqId = 8429-16) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07144591 | chr4:41053805 | APBB2 | -0.67 | 4.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | -0.0338026 | 4.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg24722777 | chr4:40844542 | APBB2 | -0.0337958 | 4.2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg22913249 | chr4:41215979 | APBB2 | 0.11 | 4.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | -0.0337665 | 4.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.034 | 4.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg22179055 | chr4:41207235 | APBB2 | 0.034 | 4.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg27434086 | chr4:41218082 | APBB2 | 0.034 | 4.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg02694037 | chr4:41125894 | APBB2 | -0.124792 | 4.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg13514532 | chr4:41145091 | APBB2 | -0.0337192 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0337151 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg06473827 | chr4:41209874 | APBB2 | 0.034 | 4.5E-05 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg27357640 | chr4:40910223 | APBB2 | -0.0691215 | 4.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.038 | 4.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.034 | 4.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | -0.0336567 | 4.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg12030017 | chr4:40893064 | APBB2 | -0.0336398 | 4.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43251 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.034 | 4.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0336273 | 4.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg07862526 | chr4:41104476 | APBB2 | 0.034 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.0336081 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.034 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.037 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.034 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q15848 | whole blood | OSCA model 2 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.047 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 2 | 14671 | cg22179055 | chr4:41207235 | APBB2 | 0.035 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg17775987 | chr4:40991374 | APBB2 | 0.034 | 4.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.034 | 4.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | 0.034 | 4.8E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | COVID-19 Severity (Hospitalisation) | Whole blood | Fully-adjusted model | 4232 | cg26865481 | chr4:41206196 | APBB2 | 0.076 | 4.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | -0.0335492 | 4.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.042 | 4.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 3 | 14671 | cg11267549 | chr4:41149137 | APBB2 | 0.034 | 4.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | 0.034 | 4.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | -0.033529 | 4.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg22179055 | chr4:41207235 | APBB2 | -0.134373 | 4.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 2 | 14671 | cg14925343 | chr4:41130621 | APBB2 | -0.0375137 | 5E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg26634049 | chr4:41126855 | APBB2 | -0.137068 | 5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg09616640 | chr4:41216812 | APBB2 | 0.033 | 5E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg08665312 | chr4:41180048 | APBB2 | -0.0099 | 5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | -0.0334686 | 5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.033 | 5.1E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg04568895 | chr4:41145263 | APBB2 | 0.15 | 5.1E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg23753351 | chr4:40860327 | APBB2 | 1.3 | 5.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 4 | 14671 | cg02774791 | chr4:41098192 | APBB2 | 0.04 | 5.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 4 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0409179 | 5.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg22913249 | chr4:41215979 | APBB2 | 0.033 | 5.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH29 | whole blood | OSCA model 4 | 14671 | cg20080580 | chr4:41172024 | APBB2 | 0.035 | 5.2E-05 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg20080580 | chr4:41172024 | APBB2 | 0.012 | 5.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | 0.033 | 5.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 2 | 14671 | cg27434086 | chr4:41218082 | APBB2 | -0.0341691 | 5.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 4 | 14671 | cg08350742 | chr4:40814531 | APBB2 | -0.0504863 | 5.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 4 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.064 | 5.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg22179055 | chr4:41207235 | APBB2 | 0.033 | 5.3E-05 |
| Gadd DA | 35945220 | IL2RB protein levels (SeqId = 9343-16) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg22913249 | chr4:41215979 | APBB2 | -0.45 | 5.3E-05 |
| Gadd DA | 35945220 | NRGN protein levels (SeqId = 18303-39) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg01921140 | chr4:40872363 | APBB2 | 0.82 | 5.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg16240468 | chr4:40871021 | APBB2 | -0.0333527 | 5.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.033 | 5.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg15989892 | chr4:41063747 | APBB2 | -0.0413166 | 5.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0333446 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | -0.0333415 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg19127966 | chr4:40827206 | APBB2 | 0.033 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH25 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0333314 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 2 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0364317 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg24644605 | chr4:40944984 | APBB2 | -0.0333257 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg14925343 | chr4:41130621 | APBB2 | -0.0371966 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg26947966 | chr4:40939389 | APBB2 | -0.0333126 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg05490745 | chr4:40814571 | APBB2 | 0.033 | 5.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg01058879 | chr4:40823935 | APBB2 | 0.033 | 5.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | 0.033 | 5.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1U7 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | 0.033 | 5.6E-05 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg07291349 | chr4:40964962 | APBB2 | 0.0052 | 5.6E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg16240468 | chr4:40871021 | APBB2 | -0.021 | 5.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg21956384 | chr4:41191857 | APBB2 | -0.0332539 | 5.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 1 | 14671 | cg12455762 | chr4:40859095 | APBB2 | 0.033 | 5.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | -0.0332242 | 5.7E-05 |
| Gadd DA | 35945220 | EFEMP1 protein levels (SeqId = 8480-29) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 0.92 | 5.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 3 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.042 | 5.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01009 | whole blood | OSCA model 1 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0332176 | 5.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.042 | 5.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0332029 | 5.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH25 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0332023 | 5.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O95445 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0332017 | 5.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 4 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0634768 | 5.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 4 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.064 | 5.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg11520308 | chr4:40861148 | APBB2 | 0.033 | 5.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg01465102 | chr4:40942131 | APBB2 | 0.034 | 5.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | -0.0331334 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.033 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg22179055 | chr4:41207235 | APBB2 | 0.033 | 6E-05 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg25333257 | chr4:41217803 | APBB2 | -0.0052 | 6E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg13978856 | chr4:40918191 | APBB2 | -0.18861 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.033121 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg08191405 | chr4:40871657 | APBB2 | -0.0331106 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg12455762 | chr4:40859095 | APBB2 | 0.033 | 6.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 3 | 14671 | cg13978856 | chr4:40918191 | APBB2 | 0.04 | 6.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH25 | whole blood | OSCA model 3 | 14671 | cg22179055 | chr4:41207235 | APBB2 | -0.0341951 | 6.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01602 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0330769 | 6.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02749 | whole blood | OSCA model 4 | 14671 | cg05490745 | chr4:40814571 | APBB2 | -0.107595 | 6.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.042 | 6.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg14464517 | chr4:41115076 | APBB2 | -0.0330627 | 6.2E-05 |
| Hoang | 34516295 | DNA methylation | malathion | whole blood | discovery | 232 | cg24644605 | chr4:40944984 | APBB2 | -0.01611 | 6.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg13690063 | chr4:40921171 | APBB2 | 0.034 | 6.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg12455762 | chr4:40859095 | APBB2 | 0.033 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | -0.0330295 | 6.3E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg09616640 | chr4:41216812 | APBB2 | 0.0019 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | 0.033 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg22913249 | chr4:41215979 | APBB2 | 0.033 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg22913249 | chr4:41215979 | APBB2 | 0.033 | 6.4E-05 |
| Hoang | 34516295 | DNA methylation | ddt | whole blood | discovery | 1140 | cg11382761 | chr4:41031037 | APBB2 | -0.00174 | 6.4E-05 |
| Soloman O | 28556291 | DNA methylation | Prenatal phthalate exposure | Cord blood | 26 weeks gestation | 332 | cg08106124 | chr4:40926641 | APBB2 | 0.15 | 6.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0329655 | 6.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | -0.0329519 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg04673478 | chr4:41124815 | APBB2 | 0.033 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg00132598 | chr4:41016918 | APBB2 | 0.033 | 6.6E-05 |
| Sharp G | 33517419 | DNA methylation | Paternal body mass index | Whole blood | Adjusted for maternal BMI using whole blood in childhood in males only | 1022 | cg08665312 | chr4:41180048 | APBB2 | -0.00343 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 1 | 14671 | cg01390277 | chr4:40827593 | APBB2 | 0.033 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0329299 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | 0.033 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg16240468 | chr4:40871021 | APBB2 | -0.0374646 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg13514532 | chr4:41145091 | APBB2 | 0.033 | 6.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 4 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0624319 | 6.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg11520308 | chr4:40861148 | APBB2 | -0.0388881 | 6.8E-05 |
| Gadd DA | 35945220 | CST3 protein levels (SeqId = 2609-59) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 0.91 | 6.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg26865481 | chr4:41206196 | APBB2 | 0.033 | 6.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 2 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0461333 | 6.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg26634049 | chr4:41126855 | APBB2 | -0.0358201 | 6.9E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg02694037 | chr4:41125894 | APBB2 | 0.0017 | 6.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.033 | 6.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg02694037 | chr4:41125894 | APBB2 | -0.121678 | 6.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg04568895 | chr4:41145263 | APBB2 | -0.146693 | 7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg24782083 | chr4:41198939 | APBB2 | 0.033 | 7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 3 | 14671 | cg22648864 | chr4:40996373 | APBB2 | 0.038 | 7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg04673478 | chr4:41124815 | APBB2 | -0.0328174 | 7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg00132598 | chr4:41016918 | APBB2 | -0.0328087 | 7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg11398467 | chr4:40829790 | APBB2 | -0.0461183 | 7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg27434086 | chr4:41218082 | APBB2 | -0.0328023 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 2 | 14671 | cg09616640 | chr4:41216812 | APBB2 | -0.0350298 | 7.1E-05 |
| Gadd DA | 35945220 | CCL15 protein levels (SeqId = 18289-16) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23753351 | chr4:40860327 | APBB2 | -0.56 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 4 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.035381 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg25486993 | chr4:40920526 | APBB2 | -0.0556514 | 7.1E-05 |
| Singmann P | 26500701 | DNA methylation | Sex | Whole blood | KORA F4 | 1799 | cg06970472 | chr4:40910981 | APBB2 | NA | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | 0.033 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg10793372 | chr4:40836027 | APBB2 | 0.043 | 7.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.04 | 7.2E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg05490745 | chr4:40814571 | APBB2 | -1.9 | 7.2E-05 |
| Gadd DA | 35945220 | LILRA5 protein levels (SeqId = 7787-25) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 0.9 | 7.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 2 | 14671 | cg01954188 | chr4:41216800 | APBB2 | 0.034 | 7.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B7B8 | whole blood | OSCA model 3 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0330308 | 7.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | 0.033 | 7.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 3 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.04 | 7.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg08016336 | chr4:41181318 | APBB2 | 0.033 | 7.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg24644605 | chr4:40944984 | APBB2 | 0.038 | 7.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg06970472 | chr4:40910981 | APBB2 | 0.033 | 7.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg07291349 | chr4:40964962 | APBB2 | -0.0482864 | 7.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg23832889 | chr4:41048727 | APBB2 | 0.033 | 7.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg00132598 | chr4:41016918 | APBB2 | -0.0326955 | 7.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg02696415 | chr4:40994566 | APBB2 | -0.0326793 | 7.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 4 | 14671 | cg06140237 | chr4:41191243 | APBB2 | -0.0476289 | 7.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | 0.033 | 7.5E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg22648864 | chr4:40996373 | APBB2 | 0.19 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0326706 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | -0.0326566 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg06140237 | chr4:41191243 | APBB2 | 0.033 | 7.7E-05 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg16433074 | chr4:41050961 | APBB2 | 0.011 | 7.7E-05 |
| Gadd DA | 35945220 | EPHA1 protein levels (SeqId = 3431-54) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg05490745 | chr4:40814571 | APBB2 | 0.92 | 7.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.033 | 7.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 1 | 14671 | cg13978856 | chr4:40918191 | APBB2 | -0.032615 | 7.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg08016336 | chr4:41181318 | APBB2 | -0.0353393 | 7.8E-05 |
| Gadd DA | 35945220 | LEFTY2 protein levels (SeqId = 15503-15) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02774791 | chr4:41098192 | APBB2 | 0.9 | 7.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg22913249 | chr4:41215979 | APBB2 | 0.033 | 7.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | -0.0325945 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0325845 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg17904897 | chr4:40995100 | APBB2 | -0.0325819 | 7.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg27434086 | chr4:41218082 | APBB2 | -0.132858 | 7.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg09219540 | chr4:40828790 | APBB2 | -0.0970976 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg18939200 | chr4:40814466 | APBB2 | -0.0630981 | 7.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg08016336 | chr4:41181318 | APBB2 | -0.221069 | 8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 4 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.044 | 8.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0325164 | 8.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 2 | 14671 | cg11267549 | chr4:41149137 | APBB2 | 0.033 | 8.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg12725265 | chr4:41169462 | APBB2 | -0.0324927 | 8.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0324885 | 8.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 3 | 14671 | cg19127966 | chr4:40827206 | APBB2 | -0.0363775 | 8.3E-05 |
| Gadd DA | 35945220 | GM2A protein levels (SeqId = 15441-6) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23681495 | chr4:40982188 | APBB2 | -0.71 | 8.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | 0.032 | 8.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg03823998 | chr4:41216517 | APBB2 | 0.12 | 8.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg12455762 | chr4:40859095 | APBB2 | 0.084 | 8.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0324448 | 8.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 1 | 14671 | cg08350742 | chr4:40814531 | APBB2 | 0.032 | 8.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 4 | 14671 | cg17699214 | chr4:40890013 | APBB2 | 0.035 | 8.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg15729315 | chr4:40992667 | APBB2 | 0.04 | 8.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg02109167 | chr4:41187789 | APBB2 | 0.032 | 8.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg20603080 | chr4:40872066 | APBB2 | 0.034 | 8.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.032 | 8.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg25886371 | chr4:40917710 | APBB2 | 0.04 | 8.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg23884217 | chr4:41147318 | APBB2 | 0.032 | 8.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 4 | 14671 | cg23884217 | chr4:41147318 | APBB2 | -0.0575362 | 8.6E-05 |
| Anna Ulrich | 38184627 | DNA methylation | Idiopathic/heritable pulmonary arterial hypertension | whole blood | Discovery | 1655 | cg15375051 | chr4:41086507 | APBB2 | 7.0 | 8.6E-05 |
| Gadd DA | 35945220 | TGFBR3 protein levels (SeqId = 3009-3) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23681495 | chr4:40982188 | APBB2 | -0.71 | 8.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg04673478 | chr4:41124815 | APBB2 | 0.032 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg01921140 | chr4:40872363 | APBB2 | 0.032 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 1 | 14671 | cg04494059 | chr4:40818170 | APBB2 | -0.0323942 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 2 | 14671 | cg04523623 | chr4:41000965 | APBB2 | -0.0343763 | 8.7E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg03153515 | chr4:41016609 | APBB2 | -0.82 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P19652 | whole blood | OSCA model 1 | 14671 | cg11398467 | chr4:40829790 | APBB2 | 0.032 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 3 | 14671 | cg02774791 | chr4:41098192 | APBB2 | -0.0324643 | 8.8E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg17904897 | chr4:40995100 | APBB2 | 0.17 | 8.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.032 | 8.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 1 | 14671 | cg09825105 | chr4:40829726 | APBB2 | -0.0323545 | 8.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg12439416 | chr4:40832685 | APBB2 | -0.0323463 | 8.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg13690063 | chr4:40921171 | APBB2 | -0.145042 | 9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg03986691 | chr4:40857415 | APBB2 | -0.129478 | 9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.032321 | 9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg07862526 | chr4:41104476 | APBB2 | -0.0323199 | 9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 3 | 14671 | cg26712140 | chr4:40842585 | APBB2 | -0.0445424 | 9.1E-05 |
| Gadd DA | 35945220 | SLITRK1 protein levels (SeqId = 15539-15) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg08670693 | chr4:41162197 | APBB2 | 0.79 | 9.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01009 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | -0.0322986 | 9.1E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | sensitivity | 18270 | cg11520308 | chr4:40861148 | APBB2 | 0.12 | 9.2E-05 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg14309469 | chr4:40817953 | APBB2 | 0.0054 | 9.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg11945554 | chr4:40857255 | APBB2 | 0.032 | 9.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg22648864 | chr4:40996373 | APBB2 | -0.0322664 | 9.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q15848 | whole blood | OSCA model 1 | 14671 | cg04568895 | chr4:41145263 | APBB2 | 0.032 | 9.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 2 | 14671 | cg03153515 | chr4:41016609 | APBB2 | -0.0333566 | 9.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg25593834 | chr4:40824632 | APBB2 | 0.032 | 9.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg09277762 | chr4:41030552 | APBB2 | -0.0322571 | 9.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg19127966 | chr4:40827206 | APBB2 | -0.109313 | 9.4E-05 |
| Gadd DA | 35945220 | CYB5R3 protein levels (SeqId = 7215-18) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg26502263 | chr4:41216644 | APBB2 | -0.66 | 9.4E-05 |
| Cardenas A | 31300640 | DNA methylation | fractional exhaled nitric oxide (FeNO) | nasal epithelium | None | 517 | cg05490745 | chr4:40814571 | APBB2 | 1.8 | 9.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg04523623 | chr4:41000965 | APBB2 | 0.032 | 9.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.032 | 9.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg26948070 | chr4:40827619 | APBB2 | 0.032 | 9.7E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg04494059 | chr4:40818170 | APBB2 | -1.3 | 9.7E-05 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg11382761 | chr4:41031037 | APBB2 | 0.0042 | 9.7E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Ischemic Heart Disease | Whole blood | Basic model | 17483 | cg19127966 | chr4:40827206 | APBB2 | -0.021 | 9.7E-05 |
| Gadd DA | 35945220 | SLC26A5 protein levels (SeqId = 9127-4) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07144591 | chr4:41053805 | APBB2 | -0.63 | 9.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 1 | 14671 | cg25186248 | chr4:40814675 | APBB2 | 0.032 | 9.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 2 | 14671 | cg13690063 | chr4:40921171 | APBB2 | 0.033 | 9.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00047667 | chr4:41202562 | APBB2 | 0.032 | 9.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0J9YX35 | whole blood | OSCA model 1 | 14671 | cg17699214 | chr4:40890013 | APBB2 | -0.0321623 | 9.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 4 | 14671 | cg07291349 | chr4:40964962 | APBB2 | 0.061 | 9.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg05020685 | chr4:40858965 | APBB2 | -0.0321558 | 9.8E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Liver Cirrhosis | Whole blood | Basic model | 18325 | cg06970472 | chr4:40910981 | APBB2 | -0.0076 | 9.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg23832889 | chr4:41048727 | APBB2 | 0.032 | 9.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH35 | whole blood | OSCA model 1 | 14671 | cg12455762 | chr4:40859095 | APBB2 | 0.032 | 9.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg15989892 | chr4:41063747 | APBB2 | 0.032 | 9.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 4 | 14671 | cg06970472 | chr4:40910981 | APBB2 | -0.0504535 | 9.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg23753351 | chr4:40860327 | APBB2 | 0.032 | 1E-04 |
Download
*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.
