Search results for CYB5R3
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg00944541 | chr22:43045525 | CYB5R3 | 0.00053 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01194538 | chr22:43043270 | CYB5R3 | -0.007 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg01194538 | chr22:43043270 | CYB5R3 | 0.014 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg04059188 | chr22:43045723 | CYB5R3 | -0.00055 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg04242898 | chr22:43043131 | CYB5R3 | -0.0019 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg09938984 | chr22:43045211 | CYB5R3 | -5.6e-05 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg19248564 | chr22:43042879 | CYB5R3 | -0.001 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg19248564 | chr22:43042879 | CYB5R3 | 0.0071 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg20950843 | chr22:43044387 | CYB5R3 | -0.0028 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0028 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg27191921 | chr22:43042910 | CYB5R3 | 0.014 | 0E+00 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg25044876 | chr22:43041146 | CYB5R3 | 0.46 | 2E-163 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg27191921 | chr22:43042910 | CYB5R3 | 0.36 | 1.6E-160 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg19248564 | chr22:43042879 | CYB5R3 | 0.33 | 2.7E-154 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg08690876 | chr22:43040721 | CYB5R3 | 0.39 | 1.8E-150 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg21827203 | chr22:43016886 | CYB5R3 | 0.54 | 1.2E-148 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg04242898 | chr22:43043131 | CYB5R3 | 0.53 | 3.9E-146 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg01194538 | chr22:43043270 | CYB5R3 | 0.57 | 1E-143 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg18535283 | chr22:43044071 | CYB5R3 | 0.42 | 4.4E-126 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg20950843 | chr22:43044387 | CYB5R3 | 0.32 | 4.5E-116 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.169334 | 8.3E-95 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.164774 | 8.3E-90 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.154858 | 2E-79 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.149572 | 3.7E-74 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg01031670 | chr22:43014920 | CYB5R3 | 0.082 | 1.1E-73 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.142957 | 7.8E-68 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.132412 | 2.2E-58 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.128606 | 3.8E-55 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.125381 | 1.8E-52 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.121743 | 1.5E-49 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg23325242 | chr22:43044788 | CYB5R3 | 2.0 | 2.8E-46 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.116866 | 8.8E-46 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg01194538 | chr22:43043270 | CYB5R3 | NA | 1.1E-44 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.112604 | 1.3E-42 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.112166 | 2.7E-42 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg20950843 | chr22:43044387 | CYB5R3 | 2.7 | 6.1E-42 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.111073 | 1.7E-41 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg18535283 | chr22:43044071 | CYB5R3 | NA | 1.7E-41 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.105603 | 1.2E-37 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.10518 | 2.3E-37 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg25044876 | chr22:43041146 | CYB5R3 | 2.3 | 3.4E-37 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg24251862 | chr22:43045736 | CYB5R3 | 0.028 | 1.9E-35 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg27191921 | chr22:43042910 | CYB5R3 | 1.3 | 2.8E-30 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0937671 | 5.2E-30 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | -0.0936064 | 6.5E-30 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0921891 | 4.6E-29 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.092 | 8.7E-29 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3962530 (gene symbol: CYB5R3) | Whole blood | Meta-analysis | 4170 | cg20727362 | chr22:43045952 | CYB5R3 | NA | 5.4E-28 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0900209 | 8.8E-28 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0893318 | 2.2E-27 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0890625 | 3.1E-27 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0869677 | 4.9E-26 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.087 | 7.3E-26 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg23325242 | chr22:43044788 | CYB5R3 | NA | 2.4E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0836857 | 3.2E-24 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg20950843 | chr22:43044387 | CYB5R3 | 0.0013 | 3.7E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0826896 | 1.1E-23 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg18535283 | chr22:43044071 | CYB5R3 | 1.6 | 1.1E-23 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0813737 | 5.5E-23 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0803782 | 1.8E-22 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.0799327 | 3.1E-22 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0787184 | 1.3E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.078 | 2.6E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | -0.0778437 | 3.6E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | -0.0778331 | 3.7E-21 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg24251862 | chr22:43045736 | CYB5R3 | NA | 1E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0755799 | 4.9E-20 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg04059188 | chr22:43045723 | CYB5R3 | 0.016 | 5.6E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | -0.0753093 | 6.6E-20 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg25044876 | chr22:43041146 | CYB5R3 | -0.36093 | 8E-20 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg19372889 | chr22:43040446 | CYB5R3 | -0.382233 | 9.1E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.074132 | 2.5E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0740054 | 2.8E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0734558 | 5.2E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0734167 | 5.4E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | -0.0714387 | 4.6E-18 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg23325242 | chr22:43044788 | CYB5R3 | 0.032 | 7.3E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.071 | 9.3E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0706112 | 1.1E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | -0.0705143 | 1.2E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0701271 | 1.8E-17 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg04242898 | chr22:43043131 | CYB5R3 | -0.30823 | 2.9E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.07 | 3.4E-17 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg20727362 | chr22:43045952 | CYB5R3 | 0.0016 | 5.2E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0688081 | 7.2E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0687502 | 7.7E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0683085 | 1.2E-16 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg01194538 | chr22:43043270 | CYB5R3 | -0.32082 | 1.7E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | 0.068 | 2.1E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.068 | 2.5E-16 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3962530 (gene symbol: CYB5R3) | Whole blood | Meta-analysis | 4170 | cg20950843 | chr22:43044387 | CYB5R3 | NA | 3.6E-16 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg23325242 | chr22:43044788 | CYB5R3 | 0.0072 | 4.4E-16 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg19372889 | chr22:43040446 | CYB5R3 | 0.35 | 7.9E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0661804 | 1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0660784 | 1.1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.065 | 2.4E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0651476 | 2.8E-15 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.065 | 4.1E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg16400025 | chr22:43045209 | CYB5R3 | -7.1e-05 | 4.4E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg18535283 | chr22:43044071 | CYB5R3 | -0.064516 | 5.2E-15 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg19248564 | chr22:43042879 | CYB5R3 | -0.15842 | 1.2E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0636707 | 1.2E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 2 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.071 | 2.1E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.063 | 2.5E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | -0.0626791 | 3E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0624214 | 3.8E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg18535283 | chr22:43044071 | CYB5R3 | -0.0616063 | 8.1E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0614326 | 9.5E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0612799 | 1.1E-13 |
| Sikdar S | 31536415 | DNA methylation | Prenatal smoke exposure | Cord blood, whole blood | Inverse varience-weighted fixed-effects meta-analysis | 5648 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0088 | 1.3E-13 |
| Joubert BR | 27040690 | DNA methylation | Maternal smoking in pregnancy | Cord blood | Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts | 5647 | cg27191921 | chr22:43042910 | CYB5R3 | -0.009 | 1.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.061 | 1.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.061 | 1.7E-13 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.06 | 3.1E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0599579 | 3.6E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.06 | 3.8E-13 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg27191921 | chr22:43042910 | CYB5R3 | -0.20283 | 4.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.0595582 | 5.2E-13 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg19372889 | chr22:43040446 | CYB5R3 | 0.31 | 6.4E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg20950843 | chr22:43044387 | CYB5R3 | 0.0062 | 8.1E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0588212 | 1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0588194 | 1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.059 | 1.1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.058711 | 1.1E-12 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg23325242 | chr22:43044788 | CYB5R3 | -0.00099 | 1.2E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.0584795 | 1.4E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0583149 | 1.6E-12 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg06341839 | chr22:43045530 | CYB5R3 | -6.9e-05 | 1.6E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0578905 | 2.3E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg10108828 | chr22:43040685 | CYB5R3 | -0.0574313 | 3.4E-12 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3962530 (gene symbol: CYB5R3) | Whole blood | Meta-analysis | 4170 | cg23325242 | chr22:43044788 | CYB5R3 | NA | 5.2E-12 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg27191921 | chr22:43042910 | CYB5R3 | NA | 5.8E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.056 | 8.1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.056 | 9E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.056 | 1.3E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0557368 | 1.4E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg10250355 | chr22:43045158 | CYB5R3 | 0.00028 | 1.5E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.055 | 1.9E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.055 | 2.1E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0803034 | 2.2E-11 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0011568 | 2.6E-11 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg25044876 | chr22:43041146 | CYB5R3 | NA | 3.3E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg19372889 | chr22:43040446 | CYB5R3 | 0.29 | 3.6E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.055 | 3.6E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | -0.0545222 | 3.9E-11 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | 0.054 | 4.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0542024 | 5E-11 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.054 | 5.6E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.054 | 5.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.054 | 5.8E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | -0.0540284 | 5.8E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | 0.054 | 6.4E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg08690876 | chr22:43040721 | CYB5R3 | 0.0014 | 6.9E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0018 | 8.2E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.053 | 1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.0531878 | 1.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.053 | 1.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.053 | 1.5E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0527557 | 1.6E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg18535283 | chr22:43044071 | CYB5R3 | -0.0013 | 1.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg10108828 | chr22:43040685 | CYB5R3 | -0.0526206 | 1.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | -0.0523495 | 2.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.052 | 2.3E-10 |
| Joubert BR | 27040690 | DNA methylation | Maternal smoking in pregnancy | Cord blood | Sustained maternal smoking in pregnancy effect on newborns | 5647 | cg27191921 | chr22:43042910 | CYB5R3 | -0.008 | 2.7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.0520213 | 2.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.052 | 3.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.075419 | 3.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0517288 | 3.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0516876 | 3.7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | 0.051 | 4.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0513794 | 4.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.051 | 4.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | -0.051256 | 5.2E-10 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg19372889 | chr22:43040446 | CYB5R3 | 2.1 | 7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0508223 | 7.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.05 | 1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg13038420 | chr22:43029372 | CYB5R3 | -0.0503265 | 1.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | -0.0565912 | 1.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0501931 | 1.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0501442 | 1.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.05 | 1.2E-09 |
| Kashima K | 33564054 | DNA methylation | gestational age | Cord blood | None | 110 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0064 | 2.1E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg20727362 | chr22:43045952 | CYB5R3 | -0.00079 | 2.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | 0.049 | 2.5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.049 | 2.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg13038420 | chr22:43029372 | CYB5R3 | -0.048949 | 3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.048661 | 3.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg20950843 | chr22:43044387 | CYB5R3 | -0.04858 | 3.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0484476 | 4.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.048 | 4.6E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | sensitivity | 18225 | cg19372889 | chr22:43040446 | CYB5R3 | -0.305702 | 4.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | -0.0482597 | 5E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg19372889 | chr22:43040446 | CYB5R3 | 0.31 | 5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | -0.0482055 | 5.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 2 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.054 | 6.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.048 | 6.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.054 | 6.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.048 | 7.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.048 | 7.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0475536 | 8.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | 0.047 | 8.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | 0.047 | 8.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.047 | 8.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | 0.047 | 9.4E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg04059188 | chr22:43045723 | CYB5R3 | 0.0023 | 9.6E-09 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg20950843 | chr22:43044387 | CYB5R3 | -0.00423 | 1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.047 | 1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | -0.0472426 | 1E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg21827203 | chr22:43016886 | CYB5R3 | -0.01116 | 1.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | 0.047 | 1.4E-08 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg19248564 | chr22:43042879 | CYB5R3 | -0.00044288 | 1.4E-08 |
| Sikdar S | 31536415 | DNA methylation | Prenatal smoke exposure | Cord blood, whole blood | Inverse varience-weighted fixed-effects meta-analysis | 5648 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0049 | 1.4E-08 |
| Joubert BR | 27040690 | DNA methylation | Maternal smoking in pregnancy | Cord blood | Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts | 5647 | cg19248564 | chr22:43042879 | CYB5R3 | -0.005 | 1.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0467675 | 1.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0467537 | 1.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0467021 | 1.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0465669 | 1.7E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg16400025 | chr22:43045209 | CYB5R3 | 0.0044 | 1.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.046 | 1.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0464239 | 1.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | 0.046 | 2.1E-08 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg23325242 | chr22:43044788 | CYB5R3 | -0.07972 | 2.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0475941 | 2.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0461437 | 2.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.046 | 2.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | 0.046 | 2.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH36 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.046 | 3.1E-08 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg09938984 | chr22:43045211 | CYB5R3 | 1.6 | 3.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.065774 | 3.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0456169 | 3.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH36 | whole blood | OSCA model 2 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.05 | 3.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0455232 | 3.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0454933 | 3.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0832231 | 3.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0453268 | 4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg05582098 | chr22:43017776 | CYB5R3 | -0.0453121 | 4E-08 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg20950843 | chr22:43044387 | CYB5R3 | -0.036 | 4.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg05582098 | chr22:43017776 | CYB5R3 | -0.045272 | 4.1E-08 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg19248564 | chr22:43042879 | CYB5R3 | NA | 4.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.045 | 4.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | 0.045 | 4.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | -0.0449639 | 5.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg18535283 | chr22:43044071 | CYB5R3 | -0.044868 | 5.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | -0.0448395 | 5.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | -0.0446624 | 6.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | -0.0445579 | 6.7E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg19372889 | chr22:43040446 | CYB5R3 | 0.29 | 7.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0455321 | 8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.044 | 8.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0442213 | 8.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg13038420 | chr22:43029372 | CYB5R3 | -0.0441685 | 8.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg05582098 | chr22:43017776 | CYB5R3 | -0.0444391 | 8.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0440616 | 9.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.044 | 1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg05582098 | chr22:43017776 | CYB5R3 | -0.0444606 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0433831 | 1.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg05582098 | chr22:43017776 | CYB5R3 | -0.0436854 | 1.7E-07 |
| Mulder RH | 33450751 | DNA methylation | age*sex | Whole blood | Discovery | 2338 | cg01194538 | chr22:43043270 | CYB5R3 | 0.0013 | 1.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | 0.043 | 1.8E-07 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0005039 | 1.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg20950843 | chr22:43044387 | CYB5R3 | -0.0430314 | 1.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.042935 | 2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg08182198 | chr22:43044351 | CYB5R3 | -0.0428452 | 2.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0428153 | 2.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH36 | whole blood | OSCA model 3 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.047 | 2.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | 0.043 | 2.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.042 | 2.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0424117 | 2.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | -0.0423902 | 2.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.042387 | 2.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg05582098 | chr22:43017776 | CYB5R3 | -0.0427452 | 3.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0421575 | 3.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | 0.042 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg10108828 | chr22:43040685 | CYB5R3 | -0.0420305 | 3.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0419758 | 3.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg08182198 | chr22:43044351 | CYB5R3 | -0.0419436 | 3.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | -0.0418021 | 4.1E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg24251862 | chr22:43045736 | CYB5R3 | 0.0036 | 4.1E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg04735755 | chr22:43032909 | CYB5R3 | -0.197311 | 4.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0416172 | 4.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH35 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.042 | 4.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | 0.042 | 4.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0413821 | 5.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.041 | 5.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | 0.041 | 5.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | -0.0412676 | 5.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0448492 | 5.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.041 | 6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0466638 | 6.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | 0.041 | 7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.041 | 7.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.074926 | 7.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg13038420 | chr22:43029372 | CYB5R3 | -0.0408159 | 7.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B7B8 | whole blood | OSCA model 1 | 14671 | cg20950843 | chr22:43044387 | CYB5R3 | 0.041 | 8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.041 | 8.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0420539 | 8.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg10108828 | chr22:43040685 | CYB5R3 | -0.0405904 | 8.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | 0.04 | 9.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | 0.04 | 9.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg05102347 | chr22:43020275 | CYB5R3 | -0.0403669 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0553074 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.04 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | 0.04 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.0399632 | 1.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0399461 | 1.3E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg01194538 | chr22:43043270 | CYB5R3 | -0.035 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 2 | 14671 | cg08182198 | chr22:43044351 | CYB5R3 | 0.043 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.04 | 1.5E-06 |
| Sharp GC | 28603561 | DNA methylation | Cleft palate vs cleft lip | Whole blood | - | 98 | cg27191921 | chr22:43042910 | CYB5R3 | -0.03665202 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.03962 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg18535283 | chr22:43044071 | CYB5R3 | 0.04 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | 0.04 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0395059 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 2 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.073 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0394645 | 1.7E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent COPD (Self-report) | Whole blood | Basic model | 18078 | cg01194538 | chr22:43043270 | CYB5R3 | -0.06 | 1.8E-06 |
| Joubert BR | 27040690 | DNA methylation | Maternal smoking in pregnancy | Cord blood | Any maternal smoking in pregnancy effect on newborns | 6685 | cg27191921 | chr22:43042910 | CYB5R3 | -0.005 | 1.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | 0.039 | 1.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0639953 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | -0.0390984 | 2.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | 0.039 | 2.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0425587 | 2.3E-06 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg19248564 | chr22:43042879 | CYB5R3 | 0.0053 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0400903 | 2.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.039 | 2.5E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg11423697 | chr22:43043182 | CYB5R3 | -0.041 | 2.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0388051 | 2.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | -0.0387389 | 2.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 3 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.04 | 2.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0386844 | 2.8E-06 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Previous week consumption discovery | 5606 | cg20950843 | chr22:43044387 | CYB5R3 | NA | 2.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0386626 | 2.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | -0.038532 | 3E-06 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Ultrasound-estimated gestational age | 1068 | cg25044876 | chr22:43041146 | CYB5R3 | -0.00073186 | 3E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg08182198 | chr22:43044351 | CYB5R3 | 0.2 | 3.2E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg00944541 | chr22:43045525 | CYB5R3 | 0.0018 | 3.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.038226 | 3.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | -0.0381846 | 3.7E-06 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg08690876 | chr22:43040721 | CYB5R3 | -0.1110132 | 3.7E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg12606162 | chr22:43014882 | CYB5R3 | 0.21 | 3.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.038 | 3.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | -0.0380748 | 4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.038019 | 4.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH35 | whole blood | OSCA model 2 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.041 | 4.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0379004 | 4.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0378762 | 4.5E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg08182198 | chr22:43044351 | CYB5R3 | 0.2 | 4.5E-06 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg16400025 | chr22:43045209 | CYB5R3 | 0.95 | 5.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg00954769 | chr22:43040691 | CYB5R3 | 0.037 | 5.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | -0.0373602 | 6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg11486643 | chr22:43045725 | CYB5R3 | 0.037 | 6.1E-06 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg00954769 | chr22:43040691 | CYB5R3 | -0.1039384 | 6.2E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg27191921 | chr22:43042910 | CYB5R3 | 0.31 | 6.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 2 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.06 | 6.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0397036 | 6.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0370807 | 7E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg25044876 | chr22:43041146 | CYB5R3 | 0.23 | 7.1E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg07711899 | chr22:43043757 | CYB5R3 | 0.21 | 7.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P13671 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0370235 | 7.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg18535283 | chr22:43044071 | CYB5R3 | 0.037 | 7.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.037 | 7.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0508769 | 7.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 4 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0453574 | 7.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0369745 | 7.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0369713 | 7.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | -0.0369624 | 7.5E-06 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg10108828 | chr22:43040685 | CYB5R3 | -0.1166398 | 7.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | 0.037 | 8E-06 |
| Gadd DA | 35945220 | PAPPA protein levels (SeqId = 4148-49) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg04242898 | chr22:43043131 | CYB5R3 | -1.33 | 8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | -0.0367609 | 8.4E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg12606162 | chr22:43014882 | CYB5R3 | -0.197554 | 8.4E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | discovery | 18270 | cg13148340 | chr22:43033866 | CYB5R3 | 0.17 | 8.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0668207 | 8.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.037 | 8.7E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg27191921 | chr22:43042910 | CYB5R3 | 0.24 | 9.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.0366036 | 9.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0365834 | 9.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0396387 | 9.5E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg23325242 | chr22:43044788 | CYB5R3 | 0.096 | 9.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.037 | 9.7E-06 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg04059188 | chr22:43045723 | CYB5R3 | 1.1 | 1.1E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg25044876 | chr22:43041146 | CYB5R3 | 0.19 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.0361784 | 1.2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg24251862 | chr22:43045736 | CYB5R3 | 0.11 | 1.3E-05 |
| Joubert BR | 27040690 | DNA methylation | Maternal smoking in pregnancy | Cord blood | Sustained maternal smoking in pregnancy effect on newborns | 5647 | cg19248564 | chr22:43042879 | CYB5R3 | -0.005 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.036 | 1.3E-05 |
| Gadd DA | 35945220 | IGF1R protein levels (SeqId = 4232-19) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg05582098 | chr22:43017776 | CYB5R3 | -0.82 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | -0.0359402 | 1.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg15072798 | chr22:43028432 | CYB5R3 | -0.135983 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg18535283 | chr22:43044071 | CYB5R3 | -0.0363789 | 1.5E-05 |
| Sikdar S | 31536415 | DNA methylation | Prenatal smoke exposure | Cord blood, whole blood | Inverse varience-weighted fixed-effects meta-analysis | 5648 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0087 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | 0.036 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.036 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | 0.036 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg18535283 | chr22:43044071 | CYB5R3 | 0.036 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P07996 | whole blood | OSCA model 3 | 14671 | cg05582098 | chr22:43017776 | CYB5R3 | -0.0359685 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.035 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.035 | 1.7E-05 |
| Gadd DA | 35945220 | PRG3 protein levels (SeqId = 9015-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg04242898 | chr22:43043131 | CYB5R3 | -1.29 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0494551 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0353088 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P07996 | whole blood | OSCA model 1 | 14671 | cg05582098 | chr22:43017776 | CYB5R3 | -0.0353061 | 1.9E-05 |
| Gadd DA | 35945220 | DPEP1 protein levels (SeqId = 8794-13) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg00944541 | chr22:43045525 | CYB5R3 | -0.95 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0522197 | 1.9E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Neutrophils | Neutrophils | 60 | cg27191921 | chr22:43042910 | CYB5R3 | -0.150807 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0515174 | 1.9E-05 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg20727362 | chr22:43045952 | CYB5R3 | 0.038 | 2E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg07711899 | chr22:43043757 | CYB5R3 | -0.035 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg13148340 | chr22:43033866 | CYB5R3 | 0.035 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.035 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 3 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0363537 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg13148340 | chr22:43033866 | CYB5R3 | -0.0373323 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | 0.035 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.035 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | -0.0392356 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg10108828 | chr22:43040685 | CYB5R3 | -0.0347319 | 2.6E-05 |
| Gadd DA | 35945220 | QPCT protein levels (SeqId = 7849-3) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg05582098 | chr22:43017776 | CYB5R3 | -0.79 | 2.6E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg19248564 | chr22:43042879 | CYB5R3 | 0.29 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg05102347 | chr22:43020275 | CYB5R3 | -0.0346773 | 2.7E-05 |
| Battram T | 23177740 | DNA methylation | Age | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279 | 656 | cg01194538 | chr22:43043270 | CYB5R3 | -0.00052 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | 0.035 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.035 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 2 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | 0.048 | 2.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.035 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0345144 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 2 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0360445 | 3E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg24251862 | chr22:43045736 | CYB5R3 | -0.00042 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0344485 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 4 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | 0.048 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg13148340 | chr22:43033866 | CYB5R3 | 0.035 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0343377 | 3.2E-05 |
| Li S | 28811542 | DNA methylation | Age | Whole blood | - | 1366 | cg01194538 | chr22:43043270 | CYB5R3 | -0.00704 | 3.2E-05 |
| Gadd DA | 35945220 | PRG2 protein levels (SeqId = 7258-5) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg04242898 | chr22:43043131 | CYB5R3 | -1.25 | 3.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P07996 | whole blood | OSCA model 2 | 14671 | cg05582098 | chr22:43017776 | CYB5R3 | -0.0347382 | 3.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 2 | 14671 | cg08182198 | chr22:43044351 | CYB5R3 | -0.0368393 | 3.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.034 | 3.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH35 | whole blood | OSCA model 3 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.037 | 3.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | -0.0341977 | 3.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0341781 | 3.5E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg12606162 | chr22:43014882 | CYB5R3 | 0.19 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01780 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.034 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg13148340 | chr22:43033866 | CYB5R3 | -0.0341461 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.034 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg13148340 | chr22:43033866 | CYB5R3 | 0.034 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | 0.034 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | -0.034091 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 2 | 14671 | cg08182198 | chr22:43044351 | CYB5R3 | 0.037 | 3.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0339623 | 3.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 3 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.062 | 4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q13790 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | -0.0338794 | 4.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0337891 | 4.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | -0.033787 | 4.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg08182198 | chr22:43044351 | CYB5R3 | 0.034 | 4.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0337679 | 4.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | -0.0357535 | 4.5E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg08182198 | chr22:43044351 | CYB5R3 | -0.174131 | 4.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg27191921 | chr22:43042910 | CYB5R3 | -0.0458337 | 4.6E-05 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg04242898 | chr22:43043131 | CYB5R3 | -0.00301 | 4.8E-05 |
| Gadd DA | 35945220 | TIE1 protein levels (SeqId = 2844-53) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg00944541 | chr22:43045525 | CYB5R3 | -0.9 | 5E-05 |
| Gadd DA | 35945220 | ATP1B4 protein levels (SeqId = 9933-49) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg05582098 | chr22:43017776 | CYB5R3 | -0.76 | 5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0490806 | 5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg18535283 | chr22:43044071 | CYB5R3 | -0.033432 | 5.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.033 | 5.2E-05 |
| Gadd DA | 35945220 | CD109 protein levels (SeqId = 3290-50) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg00944541 | chr22:43045525 | CYB5R3 | -0.9 | 5.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00944541 | chr22:43045525 | CYB5R3 | 0.033 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.033 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0493024 | 5.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0332386 | 5.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | -0.0332288 | 5.7E-05 |
| Battram T | 31851703 | DNA methylation | Leptin | Cord blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE129841 | 112 | cg24251862 | chr22:43045736 | CYB5R3 | -0.00094 | 5.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 3 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.036 | 5.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg12606162 | chr22:43014882 | CYB5R3 | -0.0331386 | 6E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg08182198 | chr22:43044351 | CYB5R3 | -0.031 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | 0.033 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 2 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.062 | 6.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0330354 | 6.3E-05 |
| Witt S | 32080920 | DNA methylation | alcohol withdrawal recovery | whole blood | discovery | 99 | cg13148340 | chr22:43033866 | CYB5R3 | 0.5 | 6.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg08690876 | chr22:43040721 | CYB5R3 | 0.033 | 6.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg23325242 | chr22:43044788 | CYB5R3 | -0.0329859 | 6.4E-05 |
| Gadd DA | 35945220 | SUMF1 protein levels (SeqId = 6941-11) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg01031670 | chr22:43014920 | CYB5R3 | -0.76 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | -0.0329242 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 1 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.033 | 6.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0478939 | 6.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 3 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0341312 | 7E-05 |
| Gadd DA | 35945220 | SPP1 protein levels (SeqId = 13113-7) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg24582896 | chr22:43040658 | CYB5R3 | -0.87 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 1 | 14671 | cg11879465 | chr22:43041118 | CYB5R3 | 0.033 | 7.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH36 | whole blood | OSCA model 1 | 14671 | cg20950843 | chr22:43044387 | CYB5R3 | 0.033 | 7.3E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Lung Cancer | Whole blood | Basic model | 18364 | cg07711899 | chr22:43043757 | CYB5R3 | -0.017 | 7.5E-05 |
| Sharp GC | 28603561 | DNA methylation | Cleft palate vs cleft lip | Whole blood | - | 98 | cg19248564 | chr22:43042879 | CYB5R3 | -0.02105617 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg01194538 | chr22:43043270 | CYB5R3 | -0.0326444 | 7.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 3 | 14671 | cg25044876 | chr22:43041146 | CYB5R3 | 0.053 | 7.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 3 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | -0.0351816 | 7.7E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg25044876 | chr22:43041146 | CYB5R3 | 0.0075 | 7.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 2 | 14671 | cg11423697 | chr22:43043182 | CYB5R3 | -0.0340148 | 7.8E-05 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg27191921 | chr22:43042910 | CYB5R3 | 0.0063 | 7.8E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Basic model | 17749 | cg11486643 | chr22:43045725 | CYB5R3 | -0.02 | 7.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg06291750 | chr22:43041232 | CYB5R3 | -0.0325971 | 7.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | 0.035 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | -0.0480784 | 8.1E-05 |
| Gadd DA | 35945220 | DPEP1 protein levels (SeqId = 8794-13) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg12606162 | chr22:43014882 | CYB5R3 | 0.86 | 8.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q13790 | whole blood | OSCA model 2 | 14671 | cg19372889 | chr22:43040446 | CYB5R3 | -0.0366338 | 8.6E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Neutrophils | Neutrophils | 60 | cg19248564 | chr22:43042879 | CYB5R3 | -0.111223 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.032 | 8.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P15169 | whole blood | OSCA model 2 | 14671 | cg04242898 | chr22:43043131 | CYB5R3 | 0.035 | 8.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | 0.032 | 9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg24582896 | chr22:43040658 | CYB5R3 | -0.0322465 | 9.4E-05 |
| Battram T | 31851703 | DNA methylation | Leptin | Cord blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE129841 | 112 | cg04059188 | chr22:43045723 | CYB5R3 | -0.00083 | 9.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg19248564 | chr22:43042879 | CYB5R3 | 0.032 | 9.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 2 | 14671 | cg18535283 | chr22:43044071 | CYB5R3 | -0.0331272 | 9.5E-05 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg18535283 | chr22:43044071 | CYB5R3 | -0.00249 | 9.6E-05 |
| Zhang L | 33257653 | DNA methylation | alzheimers disease braak stage | Prefrontal cortex | Meta-analysis | 1030 | cg18535283 | chr22:43044071 | CYB5R3 | 0.017 | 9.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg10108828 | chr22:43040685 | CYB5R3 | -0.0321563 | 9.8E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg12606162 | chr22:43014882 | CYB5R3 | 0.18 | 9.8E-05 |
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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.
