EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for EPHA4

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg00335735 chr2:222355484 EPHA4 -0.0055 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg13364311 chr2:222333289 EPHA4 -0.0017 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg13772414 chr2:222383060 EPHA4 0.0021 0E+00
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg13772414 chr2:222383060 EPHA4 0.022 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg14652038 chr2:222343519 EPHA4 -0.014 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg26538529 chr2:222437130 EPHA4 0.00048 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg26538529 chr2:222437130 EPHA4 0.0014 1.3E-176
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg09556138 chr2:222285320 EPHA4 -0.62789 8.4E-161
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg14652038 chr2:222343519 EPHA4 0.55 5.3E-146
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19245120 chr2:222411535 EPHA4 0.58 3.7E-141
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg13364311 chr2:222333289 EPHA4 0.63 1.8E-138
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg13772414 chr2:222383060 EPHA4 -0.44524 1.9E-126
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg09004195 chr2:222323493 EPHA4 0.4 1.5E-122
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg22888848 chr2:222320536 EPHA4 -0.26775 9.8E-119
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg00335735 chr2:222355484 EPHA4 0.31 2.6E-104
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg03850035 chr2:222367110 EPHA4 0.23 4.8E-99
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg05736236 chr2:222435214 EPHA4 0.00079 7.1E-95
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg05736236 chr2:222435214 EPHA4 -0.1368 2.6E-83
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg25183214 chr2:222360426 EPHA4 0.087 3.1E-82
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg16786808 chr2:222434497 EPHA4 -0.29717 1.9E-81
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg10835083 chr2:222395101 EPHA4 0.25 4.6E-73
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg00692780 chr2:222434778 EPHA4 -0.16439 2.3E-70
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg18527574 chr2:222434303 EPHA4 -0.20098 4.1E-66
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg13772414 chr2:222383060 EPHA4 NA 1.9E-65
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg10835083 chr2:222395101 EPHA4 NA 2.3E-61
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.13 3.7E-57
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.128614 3.8E-55
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.12 2.1E-48
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.11 1.4E-42
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.108532 1.1E-39
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 0.1 3.1E-37
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 0.099 2.1E-33
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg25183214 chr2:222360426 EPHA4 NA 2.4E-33
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg09556138 chr2:222285320 EPHA4 -1.37175 1.5E-28
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 0.09 1.5E-27
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 -0.0894796 1.8E-27
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.086 1E-25
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0861074 1.5E-25
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.085 6.6E-25
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg14652038 chr2:222343519 EPHA4 -1.55308 2E-23
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 0.078 3E-21
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 2600689 (gene symbol: EPHA4) Whole blood Meta-analysis 4170 cg14652038 chr2:222343519 EPHA4 NA 6.8E-21
Nones K 24500968 DNA methylation Pancreatic ductal adenocarcinoma Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata - 196 cg10835083 chr2:222395101 EPHA4 NA 2.9E-20
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19484328 chr2:222342867 EPHA4 0.023 6.4E-20
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0748174 1.1E-19
Nones K 24500968 DNA methylation Pancreatic ductal adenocarcinoma Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata - 196 cg13772414 chr2:222383060 EPHA4 NA 1.4E-19
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg13364311 chr2:222333289 EPHA4 0.27 2.4E-18
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 0.075 8.2E-18
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 0.071 8.6E-18
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 0.07 1.6E-17
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg13772414 chr2:222383060 EPHA4 2.5 3.2E-17
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg13231700 chr2:222435709 EPHA4 0.03 4.5E-17
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg03850035 chr2:222367110 EPHA4 -0.0712013 2.8E-16
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg05736236 chr2:222435214 EPHA4 0.00046 6.7E-16
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 0.071 7E-16
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg03850035 chr2:222367110 EPHA4 -0.0664121 8.1E-16
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.091 8.3E-16
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg13772414 chr2:222383060 EPHA4 -0.319836 9E-16
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg09004195 chr2:222323493 EPHA4 -0.001 1.1E-15
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg01269952 chr2:222420472 EPHA4 0.24 1.2E-15
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg13772414 chr2:222383060 EPHA4 -0.403401 1.3E-15
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg09004195 chr2:222323493 EPHA4 -1.31313 2.4E-15
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg13231700 chr2:222435709 EPHA4 -0.0011 2.4E-15
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg18527574 chr2:222434303 EPHA4 -0.034 3.3E-15
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 -0.064744 4.2E-15
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 -0.0645649 5E-15
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg01446950 chr2:222435351 EPHA4 -0.01554 6E-15
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Replication 5704 cg13772414 chr2:222383060 EPHA4 NA 7.8E-15
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 0.064 9.5E-15
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg00692780 chr2:222434778 EPHA4 -0.028 1.2E-14
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 0.063 1.6E-14
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg22888848 chr2:222320536 EPHA4 1.9 2.7E-14
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 0.063 2.8E-14
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0625313 3.4E-14
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0625263 3.5E-14
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 -0.0622753 4.4E-14
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg10517814 chr2:222436149 EPHA4 0.012 4.7E-14
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0620896 5.2E-14
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0620308 5.5E-14
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 0.061 1.1E-13
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0612461 1.1E-13
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.061167 1.2E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg05736236 chr2:222435214 EPHA4 0.002 1.4E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg13772414 chr2:222383060 EPHA4 -0.011 1.5E-13
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.061 1.6E-13
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg09004195 chr2:222323493 EPHA4 0.3 2.9E-13
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 0.06 2.9E-13
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.06 3E-13
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0600168 3.5E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg25183214 chr2:222360426 EPHA4 -0.0005 6.9E-13
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.059 8.1E-13
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg13772414 chr2:222383060 EPHA4 -0.36201 8.6E-13
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.059 8.8E-13
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg01269952 chr2:222420472 EPHA4 -0.217118 9E-13
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0588841 9.5E-13
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0587985 1E-12
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 0.058 1.5E-12
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0579951 2.1E-12
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg00335735 chr2:222355484 EPHA4 0.0022 2.2E-12
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg03850035 chr2:222367110 EPHA4 -0.00586 2.2E-12
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg01269952 chr2:222420472 EPHA4 0.069 2.7E-12
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg03850035 chr2:222367110 EPHA4 -0.389113 3.3E-12
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg24372550 chr2:222437040 EPHA4 0.00032 3.9E-12
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg03850035 chr2:222367110 EPHA4 -0.0604333 4.1E-12
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg05499262 chr2:222437089 EPHA4 -4.3e-05 4.1E-12
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 -0.0568491 5.5E-12
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0563917 8.2E-12
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 0.056 1.2E-11
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg14652038 chr2:222343519 EPHA4 0.0087 1.2E-11
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg22888848 chr2:222320536 EPHA4 0.088 1.2E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 -0.0555687 1.6E-11
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg16786808 chr2:222434497 EPHA4 -0.035 1.8E-11
Kyung WK 32795589 DNA methylation atopy nasal polyp discovery 108 cg05736236 chr2:222435214 EPHA4 -0.017 2.2E-11
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.077 2.6E-11
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.054777 3.2E-11
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg03850035 chr2:222367110 EPHA4 -2.3 3.3E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0546343 3.5E-11
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16786808 chr2:222434497 EPHA4 -0.0542591 4.8E-11
Bohlin J 27717397 DNA methylation Gestational age Cord blood Ultrasound-estimated gestational age 1068 cg13772414 chr2:222383060 EPHA4 0.00079 4.9E-11
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg01269952 chr2:222420472 EPHA4 -0.199953 5.2E-11
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg13772414 chr2:222383060 EPHA4 0.042 5.7E-11
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg01269952 chr2:222420472 EPHA4 -1.4 6.3E-11
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0536909 7.6E-11
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0536309 8E-11
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg03850035 chr2:222367110 EPHA4 0.056 1.1E-10
Kyung WK 32795589 DNA methylation atopy nasal polyp discovery 108 cg09004195 chr2:222323493 EPHA4 -0.026 1.2E-10
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0530664 1.3E-10
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg24372550 chr2:222437040 EPHA4 0.0092 1.5E-10
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg01446950 chr2:222435351 EPHA4 0.009 1.7E-10
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 -0.0526486 1.8E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 0.053 1.8E-10
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 0.053 1.9E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 -0.0520389 2.8E-10
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg13772414 chr2:222383060 EPHA4 1.9 3E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08728892 chr2:222437081 EPHA4 -5e-05 3.1E-10
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0517556 3.6E-10
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg13772414 chr2:222383060 EPHA4 NA 4.5E-10
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0514312 4.6E-10
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0512435 5.3E-10
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg03850035 chr2:222367110 EPHA4 0.051 5.5E-10
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg22888848 chr2:222320536 EPHA4 0.059 5.6E-10
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg02700328 chr2:222432475 EPHA4 0.029 6.1E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg10517814 chr2:222436149 EPHA4 0.00036 6.6E-10
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.072 7.7E-10
Imgenberg-Kreuz J 26857698 DNA methylation Primary Sjogrens syndrome Whole blood Whole blood 500 cg02700328 chr2:222432475 EPHA4 NA 7.9E-10
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 4 14671 cg03258293 chr2:222384727 EPHA4 0.069 1.1E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg03850035 chr2:222367110 EPHA4 0.0076 1.1E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg09556138 chr2:222285320 EPHA4 -0.0501958 1.2E-09
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg13772414 chr2:222383060 EPHA4 NA 1.6E-09
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 0.05 1.6E-09
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.05 1.8E-09
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg03850035 chr2:222367110 EPHA4 0.052 2.1E-09
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg08965464 chr2:222436985 EPHA4 0.0078 2.2E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg18527574 chr2:222434303 EPHA4 0.0097 2.2E-09
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg22888848 chr2:222320536 EPHA4 -0.0574475 2.6E-09
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg14963027 chr2:222385883 EPHA4 -0.0486451 3.7E-09
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 -0.0485064 4.1E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg13364311 chr2:222333289 EPHA4 0.0011 4.5E-09
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0483914 4.5E-09
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 0.048 4.6E-09
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0482274 5.1E-09
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 -0.0481362 5.4E-09
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 0.048 6.4E-09
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.048 6.4E-09
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0474774 8.7E-09
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 -0.0671997 8.8E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg14652038 chr2:222343519 EPHA4 0.0011 8.8E-09
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg13772414 chr2:222383060 EPHA4 0.0008 9.4E-09
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 0.047 9.8E-09
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 0.075 9.9E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg22888848 chr2:222320536 EPHA4 -0.0552829 1E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 -0.0471944 1.1E-08
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.047 1.1E-08
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 0.047 1.3E-08
Josephine Robertson 41361833 DNA methylation P02749 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 -0.0663441 1.4E-08
Yang BZ 23332324 DNA methylation Child abuse Saliva - 192 cg05736236 chr2:222435214 EPHA4 NA 1.5E-08
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg22475763 chr2:222309041 EPHA4 -0.055 1.5E-08
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg08787401 chr2:222383520 EPHA4 -0.1591 1.6E-08
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0466208 1.6E-08
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 0.046 1.8E-08
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg08728892 chr2:222437081 EPHA4 0.0044 1.9E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg00692780 chr2:222434778 EPHA4 -0.0462463 2.1E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg22888848 chr2:222320536 EPHA4 0.053 2.1E-08
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 -0.0461965 2.2E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 -0.0495969 2.4E-08
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 -0.0496384 2.5E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 -0.045987 2.5E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.046 2.7E-08
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.064 2.7E-08
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg01269952 chr2:222420472 EPHA4 0.046 3E-08
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg10835083 chr2:222395101 EPHA4 0.019 3.2E-08
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 -0.0490314 3.4E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg23317907 chr2:222437071 EPHA4 -7e-05 3.4E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg13364311 chr2:222333289 EPHA4 -0.0455411 3.4E-08
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 0.045 3.9E-08
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg01269952 chr2:222420472 EPHA4 -0.166913 3.9E-08
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 2 14671 cg21273862 chr2:222384688 EPHA4 0.064 3.9E-08
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 -0.0453127 4E-08
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 -0.045243 4.2E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg03776464 chr2:222436947 EPHA4 0.046 4.3E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg13364311 chr2:222333289 EPHA4 -0.240355 4.9E-08
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg13364311 chr2:222333289 EPHA4 -1.8 5.4E-08
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg03055587 chr2:222384636 EPHA4 -2.4 5.7E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg01446950 chr2:222435351 EPHA4 0.00016 5.9E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.062 6.2E-08
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg22888848 chr2:222320536 EPHA4 -0.052109 6.9E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg15808558 chr2:222437611 EPHA4 0.0002 7.1E-08
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg00335735 chr2:222355484 EPHA4 0.013 7.3E-08
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg00335735 chr2:222355484 EPHA4 0.0036 7.7E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 -0.0443496 7.7E-08
Shah S 25249537 DNA methylation Sex Whole blood Replication 445 cg13772414 chr2:222383060 EPHA4 NA 7.8E-08
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg00081574 chr2:222437836 EPHA4 0.0079 7.8E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.044 7.9E-08
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 2 14671 cg03258293 chr2:222384727 EPHA4 0.053 7.9E-08
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg08625382 chr2:222437387 EPHA4 0.011 8.1E-08
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.044 8.6E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg14963027 chr2:222385883 EPHA4 -0.0441765 8.7E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 -0.0440432 9.5E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg13772414 chr2:222383060 EPHA4 -0.212939 9.6E-08
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.044 9.7E-08
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg13364311 chr2:222333289 EPHA4 0.044 9.8E-08
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 -0.043987 9.8E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg03258293 chr2:222384727 EPHA4 -0.0530324 9.9E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg13364311 chr2:222333289 EPHA4 -0.0439508 1E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 0.047 1.1E-07
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg03850035 chr2:222367110 EPHA4 0.046 1.1E-07
Gadd DA 35945220 RAMP3 protein levels (SeqId = 15437-11) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.6 1.1E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 0.044 1.1E-07
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns 5647 cg00692780 chr2:222434778 EPHA4 0.016 1.2E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg13772414 chr2:222383060 EPHA4 0.27 1.3E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 -0.0610744 1.4E-07
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg05499262 chr2:222437089 EPHA4 0.0042 1.4E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 -0.0434478 1.4E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg03850035 chr2:222367110 EPHA4 -0.0457446 1.4E-07
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 0.043 1.5E-07
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 2 14671 cg21273862 chr2:222384688 EPHA4 0.061 1.7E-07
Shah S 25249537 DNA methylation Sex Whole blood Discovery 815 cg13772414 chr2:222383060 EPHA4 NA 1.8E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 -0.0429491 1.9E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg03055587 chr2:222384636 EPHA4 -0.051 2.3E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg09004195 chr2:222323493 EPHA4 0.00084 2.4E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg03776464 chr2:222436947 EPHA4 0.044 2.4E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg01269952 chr2:222420472 EPHA4 0.048 2.4E-07
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 0.067 2.4E-07
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg03850035 chr2:222367110 EPHA4 0.045 2.5E-07
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 4 14671 cg03258293 chr2:222384727 EPHA4 0.058 2.7E-07
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg03850035 chr2:222367110 EPHA4 -0.0067 2.7E-07
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg26538529 chr2:222437130 EPHA4 0.004 2.7E-07
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg03850035 chr2:222367110 EPHA4 0.042 2.7E-07
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.042 2.9E-07
Gadd DA 35945220 FTH1 protein levels (SeqId = 5934-1) DNA methylation Whole blood SomaScan protein measurement 774 cg13772414 chr2:222383060 EPHA4 -1.1 3.1E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg03850035 chr2:222367110 EPHA4 -0.0067 3.2E-07
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg13231700 chr2:222435709 EPHA4 0.011 3.2E-07
Gadd DA 35945220 FTL protein levels (SeqId = 15324-58) DNA methylation Whole blood SomaScan protein measurement 774 cg13772414 chr2:222383060 EPHA4 -1.09 3.2E-07
Gadd DA 35945220 KRT7 protein levels (SeqId = 11383-41) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.58 3.4E-07
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 -0.0452987 3.6E-07
Josephine Robertson 41361833 DNA methylation P01762 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.059 3.9E-07
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 3 14671 cg21273862 chr2:222384688 EPHA4 0.059 4E-07
Gadd DA 35945220 HS3ST3B1 protein levels (SeqId = 6986-17) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.58 4.2E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 0.042 4.3E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg01269952 chr2:222420472 EPHA4 -0.032 4.3E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 -0.0417201 4.3E-07
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 0.066 4.5E-07
Christiansen C 33593402 DNA methylation Smoking Whole blood Current vs never smoking meta-analysis in European samples 912 cg03258293 chr2:222384727 EPHA4 NA 5.3E-07
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 -0.0582564 5.4E-07
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0413542 5.4E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg13364311 chr2:222333289 EPHA4 -0.0413306 5.5E-07
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 3 14671 cg21273862 chr2:222384688 EPHA4 0.058 5.6E-07
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 0.041 5.7E-07
Josephine Robertson 41361833 DNA methylation P01344 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0411011 6.4E-07
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 0.041 6.4E-07
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0410158 6.7E-07
Gadd DA 35945220 C20orf173 protein levels (SeqId = 7046-6) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.56 7.3E-07
Gadd DA 35945220 HOGA1 protein levels (SeqId = 10024-44) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.56 8.2E-07
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 -0.0406864 8.2E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg03055587 chr2:222384636 EPHA4 -0.0459793 8.3E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg22888848 chr2:222320536 EPHA4 0.19 9.2E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 -0.0404648 9.4E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg27132396 chr2:222438339 EPHA4 0.00037 1E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0402663 1.1E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 -0.0401778 1.1E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg25058917 chr2:222440185 EPHA4 0.04 1.2E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 0.04 1.2E-06
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 0.063 1.2E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg03850035 chr2:222367110 EPHA4 0.04 1.3E-06
Singmann P 26500701 DNA methylation Sex Whole blood KORA F3 500 cg08625382 chr2:222437387 EPHA4 NA 1.3E-06
Gadd DA 35945220 SYN3 protein levels (SeqId = 7199-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.55 1.3E-06
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 2 14671 cg03258293 chr2:222384727 EPHA4 0.048 1.3E-06
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 0.043 1.3E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg03055587 chr2:222384636 EPHA4 -0.0449607 1.4E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg03850035 chr2:222367110 EPHA4 -0.270024 1.4E-06
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.056 1.4E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 0.04 1.5E-06
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.056 1.6E-06
Gadd DA 35945220 ADAM10 protein levels (SeqId = 8654-13) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.55 1.6E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 -0.039562 1.6E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 -0.0408318 1.6E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg22888848 chr2:222320536 EPHA4 0.046 1.7E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.04 1.7E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg10835083 chr2:222395101 EPHA4 -0.025 1.8E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 0.039 1.8E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg14963027 chr2:222385883 EPHA4 -0.0394001 1.8E-06
Josephine Robertson 41361833 DNA methylation P00748 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0393746 1.8E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 -0.0393392 1.9E-06
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.039 1.9E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg10517814 chr2:222436149 EPHA4 0.00036 2E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 0.039 2E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 -0.0525088 2.1E-06
Gadd DA 35945220 MUC1 protein levels (SeqId = 9176-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.54 2.1E-06
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 0.042 2.1E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 -0.039112 2.1E-06
Liu C 27843151 DNA methylation Alcohol consumption per day Whole blood European ancestry 9643 cg13772414 chr2:222383060 EPHA4 -0.00016136 2.2E-06
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg03850035 chr2:222367110 EPHA4 -0.264401 2.2E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg03850035 chr2:222367110 EPHA4 -0.053 2.2E-06
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg13772414 chr2:222383060 EPHA4 0.0032 2.3E-06
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous decade consumption discovery 5606 cg13772414 chr2:222383060 EPHA4 NA 2.3E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg14963027 chr2:222385883 EPHA4 -0.0413846 2.3E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg14963027 chr2:222385883 EPHA4 -0.0389387 2.4E-06
Sikdar S 31536415 DNA methylation Prenatal smoke exposure Cord blood, whole blood Inverse varience-weighted fixed-effects meta-analysis 5648 cg00692780 chr2:222434778 EPHA4 0.013 2.4E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg03850035 chr2:222367110 EPHA4 0.037 2.4E-06
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts 5647 cg00692780 chr2:222434778 EPHA4 0.014 2.4E-06
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Any maternal smoking in pregnancy effect on newborns 6685 cg00692780 chr2:222434778 EPHA4 0.011 2.5E-06
Gadd DA 35945220 CPD protein levels (SeqId = 7917-17) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.53 2.5E-06
Gadd DA 35945220 DHX38 protein levels (SeqId = 13645-14) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.53 2.5E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 -0.0387997 2.6E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg22888848 chr2:222320536 EPHA4 -0.0451469 2.7E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0386906 2.8E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 -0.0416396 2.9E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 0.039 2.9E-06
Gadd DA 35945220 C9 protein levels (SeqId = 3060-43) DNA methylation Whole blood SomaScan protein measurement 774 cg13772414 chr2:222383060 EPHA4 0.99 3E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 -0.0384902 3.1E-06
Josephine Robertson 41361833 DNA methylation A0A0A0MS15 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.054 3.2E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg22888848 chr2:222320536 EPHA4 0.22 3.3E-06
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg19245120 chr2:222411535 EPHA4 0.014 3.4E-06
Gadd DA 35945220 LRTM2 protein levels (SeqId = 8906-60) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.53 3.4E-06
Singmann P 26500701 DNA methylation Sex Whole blood KORA F3 500 cg22888848 chr2:222320536 EPHA4 NA 3.4E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 0.041 3.5E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08965464 chr2:222436985 EPHA4 0.00024 3.5E-06
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.054 3.5E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 3 14671 cg03258293 chr2:222384727 EPHA4 0.046 3.6E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0381616 3.8E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg27132396 chr2:222438339 EPHA4 0.0023 3.9E-06
Gadd DA 35945220 BTG2 protein levels (SeqId = 11325-8) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.52 3.9E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 -0.0410452 3.9E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 0.038 3.9E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg03850035 chr2:222367110 EPHA4 -0.044 4E-06
Gadd DA 35945220 EGLN1 protein levels (SeqId = 9901-28) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.52 4E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg08965464 chr2:222436985 EPHA4 0.039 4E-06
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg13772414 chr2:222383060 EPHA4 -0.00438 4.1E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg14963027 chr2:222385883 EPHA4 -0.040073 4.1E-06
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns 5647 cg18527574 chr2:222434303 EPHA4 0.014 4.2E-06
Gadd DA 35945220 ANGPTL1 protein levels (SeqId = 9092-33) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.52 4.3E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.038 4.4E-06
Gadd DA 35945220 C3orf18 protein levels (SeqId = 6994-19) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.52 4.4E-06
Gadd DA 35945220 PDIA4 protein levels (SeqId = 7146-16) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.52 4.4E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg02700328 chr2:222432475 EPHA4 -0.011 4.5E-06
Gadd DA 35945220 VSTM4 protein levels (SeqId = 7242-14) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.52 4.5E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 0.038 4.6E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg13364311 chr2:222333289 EPHA4 -0.202203 4.7E-06
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg18527574 chr2:222434303 EPHA4 0.0079 4.7E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg09556138 chr2:222285320 EPHA4 0.038 4.7E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg22475763 chr2:222309041 EPHA4 0.051 4.8E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg03776464 chr2:222436947 EPHA4 0.0013 4.8E-06
Gadd DA 35945220 PF4V1 protein levels (SeqId = 5663-18) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.52 4.8E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg03258293 chr2:222384727 EPHA4 0.038 4.8E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg03850035 chr2:222367110 EPHA4 0.038 4.8E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg01269952 chr2:222420472 EPHA4 0.045 4.9E-06
Gadd DA 35945220 CD3E protein levels (SeqId = 18870-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.52 4.9E-06
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 2 14671 cg21273862 chr2:222384688 EPHA4 0.053 5E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg06301161 chr2:222302347 EPHA4 -0.0376619 5E-06
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 3 14671 cg03850035 chr2:222367110 EPHA4 0.04 5.3E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg09556138 chr2:222285320 EPHA4 -0.0375236 5.5E-06
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0375105 5.5E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 0.059 5.5E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg00692780 chr2:222434778 EPHA4 -0.0374409 5.7E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg10871883 chr2:222290943 EPHA4 -0.179446 5.7E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 4 14671 cg03258293 chr2:222384727 EPHA4 0.051 5.8E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg17846785 chr2:222436499 EPHA4 -8.5e-05 6E-06
Gadd DA 35945220 IL10RA protein levels (SeqId = 10344-334) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.51 6E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 0.04 6E-06
Gadd DA 35945220 ST8SIA2 protein levels (SeqId = 7920-30) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.51 6.3E-06
Gadd DA 35945220 SERPINA12 protein levels (SeqId = 6551-94) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.51 6.4E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg13772414 chr2:222383060 EPHA4 0.24 6.6E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg03850035 chr2:222367110 EPHA4 0.039 6.7E-06
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg22888848 chr2:222320536 EPHA4 0.043 6.9E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg03055587 chr2:222384636 EPHA4 -0.0420322 7.1E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg18527574 chr2:222434303 EPHA4 -0.0370069 7.3E-06
Gadd DA 35945220 ACLY protein levels (SeqId = 12700-9) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.51 7.4E-06
Gadd DA 35945220 RERG protein levels (SeqId = 17822-57) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.51 7.8E-06
Gadd DA 35945220 KIAA0319L protein levels (SeqId = 13698-28) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.51 7.8E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.051 7.8E-06
Gadd DA 35945220 INSL6 protein levels (SeqId = 5754-76) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.51 7.9E-06
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0368761 7.9E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg13364311 chr2:222333289 EPHA4 0.037 7.9E-06
Gadd DA 35945220 HTR2A protein levels (SeqId = 13556-28) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.51 8E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg03850035 chr2:222367110 EPHA4 0.039 8.1E-06
Gadd DA 35945220 PAPPA protein levels (SeqId = 4148-49) DNA methylation Whole blood SomaScan protein measurement 774 cg14652038 chr2:222343519 EPHA4 -0.61 8.2E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg03258293 chr2:222384727 EPHA4 -0.039 8.2E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg19484328 chr2:222342867 EPHA4 -0.0004 8.3E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 0.039 8.4E-06
Gadd DA 35945220 UBD protein levels (SeqId = 17772-7) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.51 8.4E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.037 8.5E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg00335735 chr2:222355484 EPHA4 -0.0076 8.6E-06
Gadd DA 35945220 RELB protein levels (SeqId = 11464-9) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 8.7E-06
Gadd DA 35945220 COA3 protein levels (SeqId = 7888-58) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.51 8.8E-06
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns 5647 cg16786808 chr2:222434497 EPHA4 0.018 8.8E-06
Gadd DA 35945220 SPTLC2 protein levels (SeqId = 7267-2) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 8.9E-06
Gadd DA 35945220 CEACAM19 protein levels (SeqId = 7048-4) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 9.1E-06
Gadd DA 35945220 PCDHB1 protein levels (SeqId = 9941-70) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 9.2E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg13364311 chr2:222333289 EPHA4 0.037 9.2E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg03258293 chr2:222384727 EPHA4 -0.044027 9.3E-06
Battram T None DNA methylation 18:2 linoleic acid Whole blood None 672 cg05499262 chr2:222437089 EPHA4 -0.23 9.5E-06
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg08787401 chr2:222383520 EPHA4 -0.00713 9.5E-06
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg03776464 chr2:222436947 EPHA4 -0.0374011 9.6E-06
Gadd DA 35945220 SEPTIN10 protein levels (SeqId = 12690-33) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 9.6E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg13364311 chr2:222333289 EPHA4 0.19 9.6E-06
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.036503 9.8E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.036 9.8E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg03258293 chr2:222384727 EPHA4 -0.0439158 9.8E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg09980780 chr2:222294689 EPHA4 -0.036495 9.8E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg13364311 chr2:222333289 EPHA4 -0.0364944 9.8E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 3 14671 cg03850035 chr2:222367110 EPHA4 -0.038473 9.8E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg10871883 chr2:222290943 EPHA4 -0.175274 9.9E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg13364311 chr2:222333289 EPHA4 0.037 9.9E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 0.039 9.9E-06
Battram T 27886173 DNA methylation Ulcerative colitis Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 163 cg13772414 chr2:222383060 EPHA4 0.038 1E-05
Gadd DA 35945220 NPPB protein levels (SeqId = 16751-15) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1E-05
Gadd DA 35945220 SERF2 protein levels (SeqId = 18274-2) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1E-05
Gadd DA 35945220 ACADS protein levels (SeqId = 17393-13) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1E-05
Gadd DA 35945220 HK1 protein levels (SeqId = 13131-5) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1E-05
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts 5647 cg18527574 chr2:222434303 EPHA4 0.013 1.1E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg02700328 chr2:222432475 EPHA4 -0.0017 1.1E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg03776464 chr2:222436947 EPHA4 0.00038 1.1E-05
Battram T None DNA methylation Omega 6 fatty acids Whole blood None 672 cg05499262 chr2:222437089 EPHA4 -0.194 1.1E-05
Sikdar S 31536415 DNA methylation Prenatal smoke exposure Cord blood, whole blood Inverse varience-weighted fixed-effects meta-analysis 5648 cg18527574 chr2:222434303 EPHA4 0.013 1.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg22888848 chr2:222320536 EPHA4 0.079 1.1E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg27132396 chr2:222438339 EPHA4 0.0086 1.1E-05
Gadd DA 35945220 CDKN3 protein levels (SeqId = 14178-18) DNA methylation Whole blood SomaScan protein measurement 774 cg02754631 chr2:222290791 EPHA4 -0.63 1.1E-05
Gadd DA 35945220 ANXA8 protein levels (SeqId = 18290-6) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.1E-05
Gadd DA 35945220 SERF1A protein levels (SeqId = 7842-52) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.1E-05
Gadd DA 35945220 IL1RAPL2 protein levels (SeqId = 5082-51) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.1E-05
Gadd DA 35945220 MSR1 protein levels (SeqId = 11207-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.1E-05
Gadd DA 35945220 RMI1 protein levels (SeqId = 13926-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.1E-05
Gadd DA 35945220 PSMB5 protein levels (SeqId = 12580-7) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.1E-05
Gadd DA 35945220 SMIM13 protein levels (SeqId = 13452-113) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.1E-05
Gadd DA 35945220 AKAP7 protein levels (SeqId = 18399-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.1E-05
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 0.036 1.1E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg03850035 chr2:222367110 EPHA4 -0.0381367 1.1E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg25183214 chr2:222360426 EPHA4 -0.0362099 1.1E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 -0.0391086 1.2E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 1 14671 cg03776464 chr2:222436947 EPHA4 -0.0361974 1.2E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg19831186 chr2:222312142 EPHA4 0.037 1.2E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg08625382 chr2:222437387 EPHA4 -0.00904 1.2E-05
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg19484328 chr2:222342867 EPHA4 0.0038 1.2E-05
Gadd DA 35945220 ECE1 protein levels (SeqId = 8767-44) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.2E-05
Gadd DA 35945220 CD200R1L protein levels (SeqId = 8980-19) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.2E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 -0.0360763 1.2E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation A0A0A0MS15 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.036 1.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg25183214 chr2:222360426 EPHA4 0.028 1.3E-05
Gadd DA 35945220 TRIL protein levels (SeqId = 6527-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.3E-05
Gadd DA 35945220 RFNG protein levels (SeqId = 7203-125) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.5 1.3E-05
Gadd DA 35945220 NRBP1 protein levels (SeqId = 12616-45) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.3E-05
Gadd DA 35945220 SLC3A1 protein levels (SeqId = 9000-177) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.3E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 -0.0387696 1.3E-05
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0358881 1.4E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 0.036 1.4E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg10517814 chr2:222436149 EPHA4 0.0012 1.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg21273862 chr2:222384688 EPHA4 -0.035 1.4E-05
Gadd DA 35945220 ANP32A protein levels (SeqId = 13073-14) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.4E-05
Gadd DA 35945220 DGCR2 protein levels (SeqId = 8055-33) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.4E-05
Gadd DA 35945220 TCL1A protein levels (SeqId = 17210-2) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.4E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 -0.0386979 1.4E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg08965464 chr2:222436985 EPHA4 0.037 1.5E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg16786808 chr2:222434497 EPHA4 -0.0357397 1.5E-05
Gadd DA 35945220 ACHE protein levels (SeqId = 15553-22) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.5E-05
Gadd DA 35945220 FATE1 protein levels (SeqId = 7740-33) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.5E-05
Gadd DA 35945220 ABCC6 protein levels (SeqId = 8935-22) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.5E-05
Gadd DA 35945220 OLFM3 protein levels (SeqId = 10643-16) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.5E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg01446950 chr2:222435351 EPHA4 0.036 1.6E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg22888848 chr2:222320536 EPHA4 0.17 1.6E-05
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 2 14671 cg03055587 chr2:222384636 EPHA4 0.04 1.6E-05
Gadd DA 35945220 TNFSF4 protein levels (SeqId = 2839-2) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.6E-05
Gadd DA 35945220 GKN1 protein levels (SeqId = 15374-15) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.6E-05
Gadd DA 35945220 COL25A1 protein levels (SeqId = 7006-4) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.6E-05
Gadd DA 35945220 NR1H4 protein levels (SeqId = 8946-38) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.6E-05
Gadd DA 35945220 STAT5B protein levels (SeqId = 16551-14) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.6E-05
Gadd DA 35945220 FGB protein levels (SeqId = 18890-227) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.6E-05
Gadd DA 35945220 SIGLEC8 protein levels (SeqId = 7864-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.6E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 0.036 1.6E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg00692780 chr2:222434778 EPHA4 -0.0355742 1.6E-05
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 -0.0355256 1.7E-05
Gadd DA 35945220 LILRA4 protein levels (SeqId = 8299-66) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.7E-05
Gadd DA 35945220 HNRNPC protein levels (SeqId = 11429-80) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.7E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg22888848 chr2:222320536 EPHA4 0.041 1.7E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 0.035 1.8E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 3 14671 cg03258293 chr2:222384727 EPHA4 0.042 1.8E-05
Domingo-Relloso A 32484362 DNA methylation Smoking Whole blood Current vs never 2325 cg13772414 chr2:222383060 EPHA4 -0.047 1.8E-05
Gadd DA 35945220 NAALADL1 protein levels (SeqId = 17505-125) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.8E-05
Gadd DA 35945220 FREM2 protein levels (SeqId = 7246-4) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.8E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 4 14671 cg22888848 chr2:222320536 EPHA4 -0.0559945 1.8E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg13364311 chr2:222333289 EPHA4 -0.0355243 1.8E-05
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Any maternal smoking in pregnancy effect on newborns 6685 cg18527574 chr2:222434303 EPHA4 0.01 1.8E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16786808 chr2:222434497 EPHA4 -0.0353263 1.9E-05
Battram T None DNA methylation Saturated fatty acids Whole blood None 669 cg05499262 chr2:222437089 EPHA4 -0.151 1.9E-05
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg22888848 chr2:222320536 EPHA4 0.0048 1.9E-05
Gadd DA 35945220 SPR protein levels (SeqId = 9287-6) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.9E-05
Gadd DA 35945220 CANX protein levels (SeqId = 8834-58) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.9E-05
Gadd DA 35945220 TMEM230 protein levels (SeqId = 11542-11) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.9E-05
Gadd DA 35945220 TSNARE1 protein levels (SeqId = 7069-9) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.9E-05
Gadd DA 35945220 FHL1 protein levels (SeqId = 16814-13) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.9E-05
Gadd DA 35945220 PVRL2 protein levels (SeqId = 6245-4) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.9E-05
Gadd DA 35945220 FCAR protein levels (SeqId = 4987-17) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.9E-05
Gadd DA 35945220 FARS2 protein levels (SeqId = 13941-82) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 1.9E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 3 14671 cg00335735 chr2:222355484 EPHA4 0.036 1.9E-05
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 0.056 2E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 -0.0352316 2E-05
Battram T None DNA methylation Polyunsaturated fatty acids Whole blood None 673 cg05499262 chr2:222437089 EPHA4 -0.167 2E-05
Mulder RH 33450751 DNA methylation age*sex Whole blood Discovery 2338 cg14652038 chr2:222343519 EPHA4 0.00092 2E-05
Gadd DA 35945220 HSPA6 protein levels (SeqId = 13672-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2E-05
Gadd DA 35945220 SIGLEC11 protein levels (SeqId = 8913-22) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 2E-05
Gadd DA 35945220 KLK9 protein levels (SeqId = 5758-49) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2E-05
Gadd DA 35945220 KCNG4 protein levels (SeqId = 13525-17) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.49 2E-05
Gadd DA 35945220 C4orf32 protein levels (SeqId = 9490-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2E-05
Gadd DA 35945220 HMGA1 protein levels (SeqId = 16536-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2E-05
Gadd DA 35945220 TMPRSS15 protein levels (SeqId = 3189-61) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2E-05
Gadd DA 35945220 CCNA1 protein levels (SeqId = 15319-226) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2E-05
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg22888848 chr2:222320536 EPHA4 -0.862564 2E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 -0.0351567 2.1E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg22888848 chr2:222320536 EPHA4 -0.041075 2.1E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg13364311 chr2:222333289 EPHA4 -0.187432 2.1E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg08965464 chr2:222436985 EPHA4 0.035 2.1E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg03776464 chr2:222436947 EPHA4 0.00028 2.1E-05
Gadd DA 35945220 HS3ST4 protein levels (SeqId = 8998-15) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.1E-05
Gadd DA 35945220 TGM4 protein levels (SeqId = 18933-4) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.1E-05
Gadd DA 35945220 MYNN protein levels (SeqId = 12455-48) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.1E-05
Gadd DA 35945220 ZPBP protein levels (SeqId = 8635-283) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.1E-05
Gadd DA 35945220 PSMA1 protein levels (SeqId = 7880-9) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.1E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg23317907 chr2:222437071 EPHA4 -0.0350996 2.1E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg01269952 chr2:222420472 EPHA4 0.14 2.1E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 4 14671 cg03850035 chr2:222367110 EPHA4 -0.0483129 2.1E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg22888848 chr2:222320536 EPHA4 0.056 2.2E-05
Gadd DA 35945220 SUSD3 protein levels (SeqId = 5752-63) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.2E-05
Gadd DA 35945220 DEFB110 protein levels (SeqId = 8340-9) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.2E-05
Gadd DA 35945220 PRPF6 protein levels (SeqId = 9581-4) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.2E-05
Gadd DA 35945220 MACROD1 protein levels (SeqId = 13653-335) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.2E-05
Gadd DA 35945220 MCM6 protein levels (SeqId = 9897-9) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.2E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0349992 2.2E-05
Josephine Robertson 41361833 DNA methylation A0A0A0MS15 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 0.038 2.2E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg10835083 chr2:222395101 EPHA4 -0.0349921 2.2E-05
Gadd DA 35945220 KIF16B protein levels (SeqId = 11672-17) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.3E-05
Gadd DA 35945220 CD4 protein levels (SeqId = 3143-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.3E-05
Gadd DA 35945220 LRFN1 protein levels (SeqId = 7910-41) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.3E-05
Gadd DA 35945220 SFRP2 protein levels (SeqId = 7751-121) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.3E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 0.038 2.3E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg21273862 chr2:222384688 EPHA4 -0.0490096 2.4E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.049 2.4E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg03055587 chr2:222384636 EPHA4 -0.0394285 2.4E-05
Gadd DA 35945220 RBM19 protein levels (SeqId = 11468-15) DNA methylation Whole blood SomaScan protein measurement 774 cg03776464 chr2:222436947 EPHA4 -0.488 2.4E-05
Hoang 34516295 DNA methylation ddt whole blood discovery 1140 cg09980780 chr2:222294689 EPHA4 -0.00174 2.4E-05
Gadd DA 35945220 CHST11 protein levels (SeqId = 7779-86) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.4E-05
Gadd DA 35945220 FBL protein levels (SeqId = 13994-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.4E-05
Gadd DA 35945220 SULT2B1 protein levels (SeqId = 17209-27) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.4E-05
Gadd DA 35945220 PXDNL protein levels (SeqId = 11324-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.4E-05
Gadd DA 35945220 FGFR3 protein levels (SeqId = 3809-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.4E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg03850035 chr2:222367110 EPHA4 -0.0348636 2.4E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 -0.0376742 2.5E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg22888848 chr2:222320536 EPHA4 0.2 2.5E-05
Gadd DA 35945220 LDOC1 protein levels (SeqId = 8378-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.5E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg03850035 chr2:222367110 EPHA4 -0.0364672 2.5E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 3 14671 cg03776464 chr2:222436947 EPHA4 -0.035694 2.6E-05
Battram T 23792949 DNA methylation Ethnicity Lymphoblasts EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE39672. Compared European and African samples from HapMap (CEU and YRI) 133 cg00335735 chr2:222355484 EPHA4 -0.171 2.6E-05
Gadd DA 35945220 ZWILCH protein levels (SeqId = 18302-204) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.6E-05
Gadd DA 35945220 FCRL3 protein levels (SeqId = 4440-15) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.6E-05
Gadd DA 35945220 MGAT4A protein levels (SeqId = 9392-43) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.6E-05
Gadd DA 35945220 NGRN protein levels (SeqId = 7153-66) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.6E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0347166 2.6E-05
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg25272554 chr2:222437075 EPHA4 -0.00088 2.7E-05
Gadd DA 35945220 FAM171B protein levels (SeqId = 8786-6) DNA methylation Whole blood SomaScan protein measurement 774 cg24139506 chr2:222298497 EPHA4 0.34 2.7E-05
Gadd DA 35945220 EPHA10 protein levels (SeqId = 5076-53) DNA methylation Whole blood SomaScan protein measurement 774 cg24139506 chr2:222298497 EPHA4 0.34 2.7E-05
Gadd DA 35945220 CDH11 protein levels (SeqId = 7763-25) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.7E-05
Gadd DA 35945220 ST6GALNAC2 protein levels (SeqId = 7823-22) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.7E-05
Gadd DA 35945220 DDX25 protein levels (SeqId = 13984-23) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.7E-05
Gadd DA 35945220 EMID1 protein levels (SeqId = 9547-29) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.7E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.035 2.7E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg19831186 chr2:222312142 EPHA4 0.13 2.8E-05
Gadd DA 35945220 ASTL protein levels (SeqId = 7993-23) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.8E-05
Gadd DA 35945220 ZNF415 protein levels (SeqId = 12811-55) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.8E-05
Gadd DA 35945220 B4GALT3 protein levels (SeqId = 6921-24) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.8E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 2 14671 cg03776464 chr2:222436947 EPHA4 -0.0355207 2.8E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 0.037 2.9E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 0.055 2.9E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 2 14671 cg03055587 chr2:222384636 EPHA4 0.039 2.9E-05
Gadd DA 35945220 PI15 protein levels (SeqId = 5745-64) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.48 2.9E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg00335735 chr2:222355484 EPHA4 0.036 2.9E-05
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0344713 3E-05
Gadd DA 35945220 CELA3B protein levels (SeqId = 6357-83) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3E-05
Gadd DA 35945220 LTA protein levels (SeqId = 4703-87) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3E-05
Gadd DA 35945220 ACPL2 protein levels (SeqId = 6079-59) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3E-05
Gadd DA 35945220 ERLIN1 protein levels (SeqId = 8776-10) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg00692780 chr2:222434778 EPHA4 -0.0355278 3.1E-05
Gadd DA 35945220 C2orf40 protein levels (SeqId = 6362-6) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.1E-05
Gadd DA 35945220 CEBPA protein levels (SeqId = 18874-66) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.1E-05
Gadd DA 35945220 BCCIP protein levels (SeqId = 18304-19) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.1E-05
Gadd DA 35945220 RSPO1 protein levels (SeqId = 6240-70) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.1E-05
Gadd DA 35945220 GPNMB protein levels (SeqId = 8606-39) DNA methylation Whole blood SomaScan protein measurement 774 cg03055587 chr2:222384636 EPHA4 1.2 3.1E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 2 14671 cg03776464 chr2:222436947 EPHA4 -0.0353432 3.1E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 0.034 3.1E-05
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 0.055 3.2E-05
Gadd DA 35945220 PAPPA protein levels (SeqId = 4148-49) DNA methylation Whole blood SomaScan protein measurement 774 cg13772414 chr2:222383060 EPHA4 0.89 3.2E-05
Gadd DA 35945220 GPR135 protein levels (SeqId = 11465-4) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.2E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.048 3.3E-05
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 2 14671 cg21273862 chr2:222384688 EPHA4 0.048 3.3E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg14963027 chr2:222385883 EPHA4 -0.0342792 3.3E-05
Gadd DA 35945220 COX4I2 protein levels (SeqId = 7850-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg03258293 chr2:222384727 EPHA4 -0.031 3.5E-05
Gadd DA 35945220 IL36B protein levels (SeqId = 14149-9) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.5E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg23611672 chr2:222367424 EPHA4 -0.0341455 3.5E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg08965464 chr2:222436985 EPHA4 -0.035032 3.5E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 -0.0368075 3.6E-05
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0341219 3.6E-05
Gadd DA 35945220 HBD protein levels (SeqId = 6992-67) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.6E-05
Gadd DA 35945220 CD58 protein levels (SeqId = 10938-13) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.6E-05
Gadd DA 35945220 P2RX6 protein levels (SeqId = 7233-73) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.7E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg13364311 chr2:222333289 EPHA4 -0.0340425 3.7E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 0.034 3.7E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg01446950 chr2:222435351 EPHA4 0.034 3.8E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg09980780 chr2:222294689 EPHA4 0.029 3.8E-05
Gadd DA 35945220 CLEC4D protein levels (SeqId = 7752-31) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 3.8E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg03776464 chr2:222436947 EPHA4 0.034 3.8E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 0.037 3.9E-05
Battram T None DNA methylation Cholesterol esters in medium LDL Whole blood None 683 cg05499262 chr2:222437089 EPHA4 -0.83 3.9E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg08787401 chr2:222383520 EPHA4 0.15 4E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 -0.0527544 4E-05
Gadd DA 35945220 DNAI1 protein levels (SeqId = 11396-39) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 4E-05
Gadd DA 35945220 PFKFB3 protein levels (SeqId = 12456-5) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 4E-05
Gadd DA 35945220 UBE2A protein levels (SeqId = 17743-14) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 4E-05
Gadd DA 35945220 SCARA3 protein levels (SeqId = 11292-13) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 4E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg25272554 chr2:222437075 EPHA4 0.00013 4.1E-05
Gadd DA 35945220 APOL3 protein levels (SeqId = 16823-75) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 4.1E-05
Gadd DA 35945220 ITM2A protein levels (SeqId = 7765-15) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 4.1E-05
Gadd DA 35945220 ZP4 protein levels (SeqId = 7766-25) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 4.1E-05
Gadd DA 35945220 CHI3L2 protein levels (SeqId = 9383-24) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 4.1E-05
Gadd DA 35945220 COLEC10 protein levels (SeqId = 6558-5) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.47 4.1E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg01269952 chr2:222420472 EPHA4 -0.0403632 4.1E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg10871883 chr2:222290943 EPHA4 0.034 4.1E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0338548 4.1E-05
Josephine Robertson 41361833 DNA methylation A0A0A0MS15 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 0.037 4.1E-05
Battram T None DNA methylation Concentration of very small VLDL particles Whole blood None 685 cg05499262 chr2:222437089 EPHA4 -13000000.0 4.2E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg25272554 chr2:222437075 EPHA4 0.034 4.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg00692780 chr2:222434778 EPHA4 0.0069 4.3E-05
Gadd DA 35945220 CD72 protein levels (SeqId = 7009-8) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.3E-05
Gadd DA 35945220 RABEPK protein levels (SeqId = 13599-15) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.3E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg03776464 chr2:222436947 EPHA4 0.034 4.4E-05
Gadd DA 35945220 SCN2B protein levels (SeqId = 8353-15) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.4E-05
Gadd DA 35945220 CCNA2 protein levels (SeqId = 15574-37) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.4E-05
Josephine Robertson 41361833 DNA methylation A0A0A0MS14 whole blood OSCA model 4 14671 cg03258293 chr2:222384727 EPHA4 0.047 4.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg13772414 chr2:222383060 EPHA4 -0.029 4.5E-05
Gadd DA 35945220 CTSC protein levels (SeqId = 3178-5) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.5E-05
Gadd DA 35945220 HSPA1L protein levels (SeqId = 12041-33) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.5E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 2 14671 cg21273862 chr2:222384688 EPHA4 0.047 4.5E-05
Gadd DA 35945220 PAPPA2 protein levels (SeqId = 5756-66) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.6E-05
Gadd DA 35945220 ITGB5 protein levels (SeqId = 7755-37) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.6E-05
Gadd DA 35945220 ITGA5 protein levels (SeqId = 6932-42) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.6E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 -0.03631 4.7E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 -0.0336018 4.7E-05
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg09004195 chr2:222323493 EPHA4 0.005 4.7E-05
Gadd DA 35945220 DSC1 protein levels (SeqId = 10882-12) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.7E-05
Gadd DA 35945220 CHST14 protein levels (SeqId = 7262-191) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.7E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg02754631 chr2:222290791 EPHA4 0.034 4.7E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0335633 4.8E-05
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg22888848 chr2:222320536 EPHA4 0.0048 4.8E-05
Gadd DA 35945220 B3GNT6 protein levels (SeqId = 7082-2) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.8E-05
Gadd DA 35945220 DNAJC15 protein levels (SeqId = 7197-2) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.8E-05
Gadd DA 35945220 RNF148 protein levels (SeqId = 7742-11) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.8E-05
Gadd DA 35945220 HEPACAM2 protein levels (SeqId = 9116-28) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.8E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg03258293 chr2:222384727 EPHA4 0.04 4.8E-05
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg16786808 chr2:222434497 EPHA4 0.01 4.9E-05
Gadd DA 35945220 NRSN1 protein levels (SeqId = 11654-77) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.9E-05
Gadd DA 35945220 CCPG1 protein levels (SeqId = 8889-5) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.9E-05
Gadd DA 35945220 PSG6 protein levels (SeqId = 6456-17) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 4.9E-05
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg13772414 chr2:222383060 EPHA4 -0.981671 4.9E-05
Gadd DA 35945220 ZHX1 protein levels (SeqId = 12751-26) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5E-05
Gadd DA 35945220 KIAA1324L protein levels (SeqId = 8363-18) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5E-05
Gadd DA 35945220 RAB17 protein levels (SeqId = 11118-107) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.1E-05
Gadd DA 35945220 MRAS protein levels (SeqId = 18297-8) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.1E-05
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 3 14671 cg21273862 chr2:222384688 EPHA4 0.047 5.2E-05
Sikdar S 31536415 DNA methylation Prenatal smoke exposure Cord blood, whole blood Inverse varience-weighted fixed-effects meta-analysis 5648 cg16786808 chr2:222434497 EPHA4 0.016 5.2E-05
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts 5647 cg16786808 chr2:222434497 EPHA4 0.016 5.2E-05
Gadd DA 35945220 NISCH protein levels (SeqId = 12738-43) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.3E-05
Gadd DA 35945220 BMPR2 protein levels (SeqId = 4862-63) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.3E-05
Gadd DA 35945220 HNRNPH1 protein levels (SeqId = 14309-8) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg10835083 chr2:222395101 EPHA4 -0.0095 5.4E-05
Gadd DA 35945220 CAMP protein levels (SeqId = 9384-17) DNA methylation Whole blood SomaScan protein measurement 774 cg07916307 chr2:222288068 EPHA4 0.55 5.4E-05
Gadd DA 35945220 GORAB protein levels (SeqId = 7247-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.4E-05
Gadd DA 35945220 LSM4 protein levels (SeqId = 16854-17) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.4E-05
Gadd DA 35945220 PECAM1 protein levels (SeqId = 2695-25) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.4E-05
Gadd DA 35945220 ITPKA protein levels (SeqId = 13473-55) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.4E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 -0.0487097 5.4E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg21273862 chr2:222384688 EPHA4 0.046 5.4E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 0.033 5.5E-05
Battram T None DNA methylation Total lipids in very small VLDL Whole blood None 685 cg05499262 chr2:222437089 EPHA4 -0.86 5.5E-05
Gadd DA 35945220 PTX3 protein levels (SeqId = 6447-73) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.5E-05
Gadd DA 35945220 PCDHB2 protein levels (SeqId = 10748-216) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.5E-05
Gadd DA 35945220 DEFB135 protein levels (SeqId = 6411-58) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.5E-05
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 3 14671 cg14963027 chr2:222385883 EPHA4 -0.0352611 5.5E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 0.033 5.6E-05
Gadd DA 35945220 TXNIP protein levels (SeqId = 11682-7) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.6E-05
Gadd DA 35945220 H2AFZ protein levels (SeqId = 4163-5) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.6E-05
Gadd DA 35945220 NPPB protein levels (SeqId = 3723-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.6E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 -0.0506899 5.7E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 0.033 5.7E-05
Gadd DA 35945220 FLT1 protein levels (SeqId = 16315-105) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.7E-05
Gadd DA 35945220 RNF43 protein levels (SeqId = 14120-2) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.7E-05
Gadd DA 35945220 BAG3 protein levels (SeqId = 10078-5) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.7E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.046 5.7E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg21273862 chr2:222384688 EPHA4 0.047 5.8E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg06301161 chr2:222302347 EPHA4 -0.0332043 5.8E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg03055587 chr2:222384636 EPHA4 0.038 5.8E-05
Gadd DA 35945220 PMEPA1 protein levels (SeqId = 6936-7) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.8E-05
Gadd DA 35945220 TAC4 protein levels (SeqId = 6468-37) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.8E-05
Gadd DA 35945220 TACSTD2 protein levels (SeqId = 14034-22) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.8E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg19831186 chr2:222312142 EPHA4 0.033 5.8E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 -0.0331858 5.8E-05
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg00692780 chr2:222434778 EPHA4 0.0067 5.9E-05
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Any maternal smoking in pregnancy effect on newborns 6685 cg16786808 chr2:222434497 EPHA4 0.013 5.9E-05
Gadd DA 35945220 PAXIP1 protein levels (SeqId = 12894-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 5.9E-05
Gadd DA 35945220 ZBTB33 protein levels (SeqId = 12785-49) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 6E-05
Gadd DA 35945220 DEFB107A protein levels (SeqId = 6399-52) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 6E-05
Gadd DA 35945220 CSF2RB protein levels (SeqId = 11137-43) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 6E-05
Gadd DA 35945220 HNRNPR protein levels (SeqId = 13512-28) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 6E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg13029853 chr2:222418040 EPHA4 -0.0330952 6.1E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 -0.033092 6.1E-05
Gadd DA 35945220 USP28 protein levels (SeqId = 19562-8) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.46 6.1E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg03850035 chr2:222367110 EPHA4 -0.0330623 6.2E-05
Gadd DA 35945220 C1GALT1C1 protein levels (SeqId = 5735-54) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.2E-05
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 2 14671 cg13772414 chr2:222383060 EPHA4 -0.035728 6.2E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg10871883 chr2:222290943 EPHA4 -0.160669 6.3E-05
Gadd DA 35945220 GRAP2 protein levels (SeqId = 16074-12) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.3E-05
Battram T None DNA methylation Total cholesterol in small VLDL Whole blood None 684 cg05499262 chr2:222437089 EPHA4 -1.43 6.4E-05
Gadd DA 35945220 CD207 protein levels (SeqId = 3361-26) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.4E-05
Gadd DA 35945220 DKKL1 protein levels (SeqId = 16309-30) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.4E-05
Gadd DA 35945220 GNGT2 protein levels (SeqId = 10917-40) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.4E-05
Gadd DA 35945220 UTS2 protein levels (SeqId = 6020-52) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.4E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg01269952 chr2:222420472 EPHA4 0.039 6.4E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 -0.035514 6.5E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg01269952 chr2:222420472 EPHA4 -0.0329653 6.5E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 3 14671 cg22475763 chr2:222309041 EPHA4 0.044 6.6E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg00692780 chr2:222434778 EPHA4 -0.0329481 6.6E-05
Gadd DA 35945220 POTEG protein levels (SeqId = 7960-53) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.6E-05
Battram T None DNA methylation Phospholipids in medium LDL Whole blood None 685 cg05499262 chr2:222437089 EPHA4 -2.6 6.7E-05
Gadd DA 35945220 RELT protein levels (SeqId = 14112-40) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.7E-05
Gadd DA 35945220 CUL9 protein levels (SeqId = 12991-49) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.7E-05
Gadd DA 35945220 TCP11 protein levels (SeqId = 8334-65) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.7E-05
Gadd DA 35945220 PPIG protein levels (SeqId = 18449-33) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.7E-05
Gadd DA 35945220 UBE2C protein levels (SeqId = 12556-7) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.7E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 3 14671 cg23317907 chr2:222437071 EPHA4 -0.0327804 6.7E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg03055587 chr2:222384636 EPHA4 -0.0386839 6.8E-05
Battram T None DNA methylation Phospholipids in very small VLDL Whole blood None 685 cg05499262 chr2:222437089 EPHA4 -2.6 6.8E-05
Battram T None DNA methylation Total cholesterol in VLDL Whole blood None 681 cg05499262 chr2:222437089 EPHA4 -0.46 6.8E-05
Gadd DA 35945220 IGFLR1 protein levels (SeqId = 7244-16) DNA methylation Whole blood SomaScan protein measurement 774 cg13772414 chr2:222383060 EPHA4 0.85 6.8E-05
Gadd DA 35945220 QRFP protein levels (SeqId = 6463-59) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.8E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg19831186 chr2:222312142 EPHA4 0.033 6.9E-05
Battram T None DNA methylation LDL cholesterol Whole blood fasting 692 cg05499262 chr2:222437089 EPHA4 -0.134 6.9E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg09004195 chr2:222323493 EPHA4 0.0027 6.9E-05
Gadd DA 35945220 CRIPT protein levels (SeqId = 19294-26) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.9E-05
Gadd DA 35945220 SIGLEC15 protein levels (SeqId = 10847-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.9E-05
Gadd DA 35945220 FGF3 protein levels (SeqId = 7894-155) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.9E-05
Gadd DA 35945220 ENTPD1 protein levels (SeqId = 3182-38) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 6.9E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg09556138 chr2:222285320 EPHA4 0.033 7E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg22888848 chr2:222320536 EPHA4 -0.0384333 7E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg13364311 chr2:222333289 EPHA4 -0.032826 7E-05
Gadd DA 35945220 NPM1 protein levels (SeqId = 8870-38) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7E-05
Battram T None DNA methylation Cholesterol esters in small LDL Whole blood None 683 cg05499262 chr2:222437089 EPHA4 -1.3 7.1E-05
Gadd DA 35945220 SERPINI2 protein levels (SeqId = 7117-21) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.1E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg22888848 chr2:222320536 EPHA4 0.0075 7.2E-05
Gadd DA 35945220 CD38 protein levels (SeqId = 11513-92) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.2E-05
Gadd DA 35945220 KCNE5 protein levels (SeqId = 8756-41) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.2E-05
Gadd DA 35945220 JPH4 protein levels (SeqId = 9111-40) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.2E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 0.033 7.3E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 1 14671 cg03850035 chr2:222367110 EPHA4 -0.0327221 7.4E-05
Gadd DA 35945220 TMEM38B protein levels (SeqId = 9509-4) DNA methylation Whole blood SomaScan protein measurement 774 cg18527574 chr2:222434303 EPHA4 0.32 7.4E-05
Gadd DA 35945220 CALN1 protein levels (SeqId = 10933-107) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.4E-05
Gadd DA 35945220 STX1B protein levels (SeqId = 6966-144) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.4E-05
Gadd DA 35945220 LCN1 protein levels (SeqId = 11708-2) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.4E-05
Gadd DA 35945220 PARP1 protein levels (SeqId = 10534-40) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.4E-05
Gadd DA 35945220 B4GALT5 protein levels (SeqId = 10425-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.4E-05
Gadd DA 35945220 ACVR2A protein levels (SeqId = 19208-8) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.4E-05
Gadd DA 35945220 PTPN9 protein levels (SeqId = 12633-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.4E-05
Gadd DA 35945220 BMP8B protein levels (SeqId = 15668-19) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.4E-05
Gadd DA 35945220 RNF24 protein levels (SeqId = 9583-17) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.4E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08787401 chr2:222383520 EPHA4 -0.0002 7.5E-05
Gadd DA 35945220 GOSR1 protein levels (SeqId = 7805-52) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.5E-05
Gadd DA 35945220 CD70 protein levels (SeqId = 5807-77) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.5E-05
Gadd DA 35945220 TNFSF13B protein levels (SeqId = 3059-50) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.5E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg03850035 chr2:222367110 EPHA4 0.033 7.6E-05
Xu C-J 34473906 DNA methylation RSV immunoprophylaxis in infancy nasal epithelium None 274 cg24139506 chr2:222298497 EPHA4 -0.233 7.6E-05
Gadd DA 35945220 CNTNAP5 protein levels (SeqId = 9044-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.6E-05
Gadd DA 35945220 GRAMD1C protein levels (SeqId = 8336-267) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.6E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.033 7.7E-05
Gadd DA 35945220 RAG1 protein levels (SeqId = 11311-79) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.7E-05
Gadd DA 35945220 VPS28 protein levels (SeqId = 17155-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.7E-05
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.046 7.7E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg13364311 chr2:222333289 EPHA4 0.033 7.8E-05
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.033 7.8E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg25058917 chr2:222440185 EPHA4 0.091 7.8E-05
Battram T None DNA methylation Free cholesterol in very small VLDL Whole blood None 685 cg05499262 chr2:222437089 EPHA4 -5.0 7.8E-05
Gadd DA 35945220 FAM174A protein levels (SeqId = 6597-24) DNA methylation Whole blood SomaScan protein measurement 774 cg01536875 chr2:222291194 EPHA4 0.68 7.9E-05
Gadd DA 35945220 MMP14 protein levels (SeqId = 5002-76) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 7.9E-05
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 0.033 7.9E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg06301161 chr2:222302347 EPHA4 -0.0325831 7.9E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg14963027 chr2:222385883 EPHA4 -0.0325778 7.9E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 -0.0325776 7.9E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg22888848 chr2:222320536 EPHA4 0.038 8E-05
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 3 14671 cg13772414 chr2:222383060 EPHA4 0.035 8E-05
Gadd DA 35945220 CD247 protein levels (SeqId = 15567-2) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8E-05
Gadd DA 35945220 PIK3C2A protein levels (SeqId = 14028-22) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8E-05
Gadd DA 35945220 S100A10 protein levels (SeqId = 15318-75) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.1E-05
Gadd DA 35945220 ANKRD1 protein levels (SeqId = 15361-37) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.1E-05
Gadd DA 35945220 TNFSF11 protein levels (SeqId = 14061-48) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.1E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 0.033 8.2E-05
Gadd DA 35945220 STX2 protein levels (SeqId = 7738-299) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.2E-05
Josephine Robertson 41361833 DNA methylation A0A0A0MS14 whole blood OSCA model 4 14671 cg21273862 chr2:222384688 EPHA4 0.052 8.3E-05
Gadd DA 35945220 MMP16 protein levels (SeqId = 9719-145) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.3E-05
Gadd DA 35945220 MTPAP protein levels (SeqId = 9028-5) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.3E-05
Gadd DA 35945220 GAL3ST1 protein levels (SeqId = 8696-15) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.3E-05
Gadd DA 35945220 PTS protein levels (SeqId = 12014-19) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.3E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 3 14671 cg21273862 chr2:222384688 EPHA4 -0.0446989 8.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Lung Cancer Whole blood Basic model 18364 cg22888848 chr2:222320536 EPHA4 0.014 8.4E-05
Gadd DA 35945220 GADD45GIP1 protein levels (SeqId = 9302-90) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.4E-05
Gadd DA 35945220 EVL protein levels (SeqId = 11656-110) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.4E-05
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 -0.0324541 8.4E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 -0.032441 8.5E-05
Battram T None DNA methylation Triglycerides in very small VLDL Whole blood None 680 cg05499262 chr2:222437089 EPHA4 -3.0 8.5E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg25183214 chr2:222360426 EPHA4 0.0004 8.5E-05
Gadd DA 35945220 LILRA5 protein levels (SeqId = 7787-25) DNA methylation Whole blood SomaScan protein measurement 774 cg13772414 chr2:222383060 EPHA4 0.84 8.6E-05
Gadd DA 35945220 FUT2 protein levels (SeqId = 9121-28) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.6E-05
Gadd DA 35945220 CYTH2 protein levels (SeqId = 12533-135) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.6E-05
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 3 14671 cg21273862 chr2:222384688 EPHA4 0.046 8.6E-05
Gadd DA 35945220 IFNG protein levels (SeqId = 15346-31) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.7E-05
Gadd DA 35945220 PLA2G2C protein levels (SeqId = 8850-5) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.7E-05
Gadd DA 35945220 CLTC protein levels (SeqId = 13711-10) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.7E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg00335735 chr2:222355484 EPHA4 -0.0323924 8.7E-05
Gadd DA 35945220 HRK protein levels (SeqId = 8008-28) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.8E-05
Gadd DA 35945220 SEMA6C protein levels (SeqId = 7202-107) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.9E-05
Gadd DA 35945220 GRB7 protein levels (SeqId = 11281-6) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 8.9E-05
Gadd DA 35945220 BCL2L2 protein levels (SeqId = 13097-11) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.9E-05
Gadd DA 35945220 SCARF2 protein levels (SeqId = 9925-56) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.9E-05
Gadd DA 35945220 CUL1 protein levels (SeqId = 17797-1) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 8.9E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 4 14671 cg10517814 chr2:222436149 EPHA4 -0.0337939 8.9E-05
Battram T None DNA methylation Total lipids in medium LDL Whole blood None 685 cg05499262 chr2:222437089 EPHA4 -0.49 9E-05
Gadd DA 35945220 RAET1G protein levels (SeqId = 18927-14) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 9E-05
Gadd DA 35945220 C19orf18 protein levels (SeqId = 9445-44) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 9E-05
Gadd DA 35945220 SOS1 protein levels (SeqId = 9923-6) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9E-05
Gadd DA 35945220 CCNB2 protein levels (SeqId = 18208-3) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg09556138 chr2:222285320 EPHA4 -0.0323175 9E-05
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg10835083 chr2:222395101 EPHA4 0.00059 9E-05
Battram T None DNA methylation Remnant cholesterol (non-HDL, non-LDL -cholesterol) Whole blood None 684 cg05499262 chr2:222437089 EPHA4 -0.27 9.1E-05
Gadd DA 35945220 TOM1L1 protein levels (SeqId = 13652-2) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.45 9.1E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 0.045 9.1E-05
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 1 14671 cg22888848 chr2:222320536 EPHA4 0.032 9.2E-05
Gadd DA 35945220 MAD2L1 protein levels (SeqId = 15313-28) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.2E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 4 14671 cg03055587 chr2:222384636 EPHA4 0.041 9.2E-05
Gadd DA 35945220 LRRN1 protein levels (SeqId = 11293-14) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.3E-05
Gadd DA 35945220 ITM2C protein levels (SeqId = 9523-34) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.3E-05
Gadd DA 35945220 PRKAA1 protein levels (SeqId = 5183-53) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.3E-05
Gadd DA 35945220 PRLR protein levels (SeqId = 5114-65) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.3E-05
Gadd DA 35945220 SMURF2 protein levels (SeqId = 13985-12) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.3E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 -0.0322518 9.3E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg13772414 chr2:222383060 EPHA4 0.032 9.4E-05
Gadd DA 35945220 TAF10 protein levels (SeqId = 18270-10) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.4E-05
Gadd DA 35945220 LRRC74A protein levels (SeqId = 8389-8) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.4E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 0.032 9.4E-05
Fernandez-Jimenez N None DNA methylation maternal pre-pregnancy body mass index Placenta inverse variance-weighted fixed effects meta-analysis 2631 cg05736236 chr2:222435214 EPHA4 0.0014 9.5E-05
Gadd DA 35945220 SGTB protein levels (SeqId = 18837-9) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.5E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 -0.032207 9.6E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg03776464 chr2:222436947 EPHA4 0.032 9.6E-05
Battram T None DNA methylation Esterified cholesterol Whole blood None 673 cg05499262 chr2:222437089 EPHA4 -0.177 9.6E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0321837 9.7E-05
Gadd DA 35945220 IFNA2 protein levels (SeqId = 3497-13) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.7E-05
Gadd DA 35945220 NXPH3 protein levels (SeqId = 6054-6) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.7E-05
Gadd DA 35945220 KPNA1 protein levels (SeqId = 19587-12) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.7E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg22475763 chr2:222309041 EPHA4 -0.0321757 9.7E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg24372550 chr2:222437040 EPHA4 0.13 9.7E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg01269952 chr2:222420472 EPHA4 0.038 9.8E-05
Gadd DA 35945220 ITIH3 protein levels (SeqId = 7145-1) DNA methylation Whole blood SomaScan protein measurement 774 cg09004195 chr2:222323493 EPHA4 0.71 9.8E-05
Gadd DA 35945220 ADCYAP1 protein levels (SeqId = 8446-4) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.8E-05
Gadd DA 35945220 OCIAD1 protein levels (SeqId = 16802-31) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.8E-05
Gadd DA 35945220 CSNK2A2 protein levels (SeqId = 13681-173) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.8E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg21273862 chr2:222384688 EPHA4 -0.0321537 9.8E-05
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 -0.0321491 9.8E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg13772414 chr2:222383060 EPHA4 -0.0453257 9.8E-05
Gadd DA 35945220 PSMD10 protein levels (SeqId = 18385-4) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.9E-05
Gadd DA 35945220 HS3ST4 protein levels (SeqId = 19370-30) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.9E-05
Gadd DA 35945220 TMPRSS11A protein levels (SeqId = 7231-37) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.9E-05
Gadd DA 35945220 CHEK1 protein levels (SeqId = 2853-68) DNA methylation Whole blood SomaScan protein measurement 774 cg25058917 chr2:222440185 EPHA4 0.44 9.9E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg03850035 chr2:222367110 EPHA4 -0.0336358 9.9E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg03055587 chr2:222384636 EPHA4 -0.0321327 9.9E-05

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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