EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for LCT

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg04750100 chr2:136595281 LCT 0.0025 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg15123519 chr2:136567270 LCT -0.0028 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg17750252 chr2:136567154 LCT -0.0011 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg20242066 chr2:136595261 LCT 0.0024 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg20697578 chr2:136545738 LCT -0.0017 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg23851026 chr2:136556271 LCT 0.0019 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg25344623 chr2:136566232 LCT -0.0027 0E+00
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg20242066 chr2:136595261 LCT -0.20454 1.4E-77
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg23851026 chr2:136556271 LCT -0.16232 6.3E-77
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg04750100 chr2:136595281 LCT -0.27714 6E-75
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg25344623 chr2:136566232 LCT 0.11 2.5E-70
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT -0.10785 3.3E-39
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg21375825 chr2:136594646 LCT NA 4E-38
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg07305463 chr2:136567211 LCT 0.052 1.2E-37
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg25344623 chr2:136566232 LCT 0.0017 1E-36
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT -0.0877877 1.7E-26
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT -0.0872409 3.5E-26
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg02668124 chr2:136556590 LCT 0.31 3.9E-24
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg15123519 chr2:136567270 LCT -0.381703 1.1E-23
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT -0.0818648 3E-23
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT -0.081088 7.8E-23
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT 0.081 8E-23
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg15123519 chr2:136567270 LCT NA 1.1E-22
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT -0.0807167 1.2E-22
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg02668124 chr2:136556590 LCT 3.3 1.8E-20
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg12515326 chr2:136556580 LCT 0.31 3.3E-20
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 2577896 (gene symbol: MCM6) Whole blood Meta-analysis 4170 cg20242066 chr2:136595261 LCT NA 3.5E-20
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT -0.0724684 1.5E-18
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg01986081 chr2:136552499 LCT 0.25 4.2E-17
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg12515326 chr2:136556580 LCT 3.4 1.8E-16
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 2577896 (gene symbol: MCM6) Whole blood Meta-analysis 4170 cg15123519 chr2:136567270 LCT NA 2.8E-16
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg15123519 chr2:136567270 LCT -0.71671756 2.8E-16
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg25344623 chr2:136566232 LCT 0.0052 1.1E-15
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg12515326 chr2:136556580 LCT 0.26 6E-15
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg02668124 chr2:136556590 LCT 0.24 1.2E-14
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg02668124 chr2:136556590 LCT 0.23 5.6E-14
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg15123519 chr2:136567270 LCT -0.285028 8E-14
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg09370299 chr2:136577346 LCT -0.0003 2.2E-13
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT -0.0604961 2.2E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg07305463 chr2:136567211 LCT 0.0012 3.8E-13
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT 0.06 4.4E-13
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg26091981 chr2:136594866 LCT 0.018 5.7E-13
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT -0.0706658 5.8E-13
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT 0.057 3.6E-12
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT -0.0571044 4.5E-12
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT -0.0567162 6.2E-12
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT -0.0691966 7.4E-12
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg01986081 chr2:136552499 LCT 0.2 8E-12
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg20697578 chr2:136545738 LCT 0.0012 8.8E-12
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg15123519 chr2:136567270 LCT -0.259507 9E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT 0.067 1.1E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT -0.0559716 1.2E-11
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT -0.0681108 1.8E-11
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 2577896 (gene symbol: MCM6) Whole blood Meta-analysis 4170 cg23851026 chr2:136556271 LCT NA 1.9E-11
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg12515326 chr2:136556580 LCT 0.22 2.2E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT 0.055 2.3E-11
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT 0.066 2.3E-11
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT 0.067 3.2E-11
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg07305463 chr2:136567211 LCT -0.0011 3.4E-11
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg10019301 chr2:136574079 LCT -0.0582582 5.3E-11
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg10019301 chr2:136574079 LCT -0.0535939 8.3E-11
Li S 28811542 DNA methylation Age Whole blood - 1366 cg15123519 chr2:136567270 LCT -0.0152 8.7E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT -0.0531417 1.2E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT -0.0530633 1.3E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg23851026 chr2:136556271 LCT 0.0088 1.6E-10
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg20242066 chr2:136595261 LCT 0.0071 3.4E-10
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.052 3.9E-10
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT -0.0515513 4.2E-10
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT 0.061 4.3E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg04750100 chr2:136595281 LCT 0.0022 4.9E-10
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg07305463 chr2:136567211 LCT -0.015 5.1E-10
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg15123519 chr2:136567270 LCT -0.0573156 6.3E-10
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg02668124 chr2:136556590 LCT -0.183246 7.4E-10
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT -0.0618271 1E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT -0.0503611 1E-09
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg12515326 chr2:136556580 LCT -0.194115 1.9E-09
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT -0.049288 2.3E-09
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.049 3.1E-09
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT -0.0579703 3.8E-09
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT -0.0484754 4.2E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT -0.0479359 6.3E-09
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg15123519 chr2:136567270 LCT 0.053 6.9E-09
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.048 7.6E-09
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT -0.0475975 8E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg10019301 chr2:136574079 LCT -0.0474049 9.2E-09
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT 0.058 9.8E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT 0.047 9.9E-09
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT -0.0464844 1.8E-08
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT -0.0463718 1.9E-08
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg15123519 chr2:136567270 LCT 0.052 2E-08
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg15123519 chr2:136567270 LCT -1.4 2.6E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg02668124 chr2:136556590 LCT 0.18 2.6E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT 0.056 2.6E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT 0.055 4.2E-08
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT -0.0445461 6.7E-08
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.044 7.5E-08
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg23851026 chr2:136556271 LCT -0.014 8.1E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg23851026 chr2:136556271 LCT 0.15 8.6E-08
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.044 9.5E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg10019301 chr2:136574079 LCT -0.275236 1E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg20697578 chr2:136545738 LCT 0.004 1.1E-07
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg23851026 chr2:136556271 LCT 0.15 1.2E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg26091981 chr2:136594866 LCT 0.0012 1.4E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg15123519 chr2:136567270 LCT -0.0487739 1.4E-07
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg01986081 chr2:136552499 LCT 0.16 1.6E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT 0.043 1.7E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg02668124 chr2:136556590 LCT 0.073 1.7E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg20242066 chr2:136595261 LCT 0.02 2.1E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT -0.0426805 2.3E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg12515326 chr2:136556580 LCT 0.035 2.4E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg15123519 chr2:136567270 LCT 0.0068 2.5E-07
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.043 2.5E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT 0.051 2.7E-07
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg15123519 chr2:136567270 LCT 0.047 3E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg02668124 chr2:136556590 LCT 0.032 3.1E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT -0.0513188 3.8E-07
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT -0.0418489 4E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg10019301 chr2:136574079 LCT -0.0428844 4.4E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT -0.0496645 4.5E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg02668124 chr2:136556590 LCT -0.0510785 4.8E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT 0.041 5.7E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg23851026 chr2:136556271 LCT 0.0017 5.7E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg15123519 chr2:136567270 LCT -0.0456315 6.4E-07
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT -0.0410731 6.5E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT 0.04 1.3E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 3 14671 cg12515326 chr2:136556580 LCT 0.047 1.3E-06
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg14667406 chr2:136577303 LCT 0.0015 1.5E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT 0.047 1.9E-06
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.039 1.9E-06
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT -0.0389781 2.3E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT -0.0389586 2.4E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT -0.0476906 2.5E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg10019301 chr2:136574079 LCT -0.0387119 2.7E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT -0.046186 2.7E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT -0.0472701 3.1E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg10019301 chr2:136574079 LCT 0.041 3.2E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT 0.046 3.3E-06
Odintsova VV 31744183 DNA methylation Breastfeeding duration Buccal cells Discovery, adjusted model, total sample 1006 cg04750100 chr2:136595281 LCT 0.0083 3.6E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg12515326 chr2:136556580 LCT 0.07 3.8E-06
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.038 4E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg12515326 chr2:136556580 LCT 0.16 4.1E-06
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.038 4.2E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg21375825 chr2:136594646 LCT -0.137494 5E-06
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.038 5.1E-06
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg20242066 chr2:136595261 LCT -0.00074709 5.3E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg01986081 chr2:136552499 LCT 2.5 5.3E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg12515326 chr2:136556580 LCT 0.044 5.5E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT 0.037 5.6E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg10019301 chr2:136574079 LCT -0.0374579 5.7E-06
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg01986081 chr2:136552499 LCT 0.047 5.8E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg23851026 chr2:136556271 LCT 0.82 6E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg23851026 chr2:136556271 LCT -0.0382984 6.3E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT -0.0372604 6.4E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT 0.046 7E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg15123519 chr2:136567270 LCT 0.042 7.1E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg15123519 chr2:136567270 LCT 0.17 7.4E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT -0.0369221 7.7E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg10292250 chr2:136595995 LCT -0.0683167 7.9E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg16536143 chr2:136570445 LCT -0.21423 8.2E-06
Zhu X 26756918 DNA methylation Smoking Whole blood - 596 cg14667406 chr2:136577303 LCT -0.212 8.7E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 2 14671 cg20242066 chr2:136595261 LCT -0.0374544 8.8E-06
Josephine Robertson 41361833 DNA methylation P23142 whole blood OSCA model 2 14671 cg15123519 chr2:136567270 LCT 0.041 9E-06
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT -0.0437062 9.1E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Lung Cancer Whole blood Basic model 18364 cg20242066 chr2:136595261 LCT 0.0092 9.4E-06
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.036 9.9E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg12515326 chr2:136556580 LCT -0.041664 9.9E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT -0.0433287 1E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT 0.036 1.1E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT -0.0446408 1.1E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg23276673 chr2:136577322 LCT 0.00073 1.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg12515326 chr2:136556580 LCT 0.025 1.1E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg23851026 chr2:136556271 LCT -0.03721 1.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg23851026 chr2:136556271 LCT 0.058 1.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg02668124 chr2:136556590 LCT 0.023 1.2E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT -0.0442608 1.2E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.036 1.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg22832131 chr2:136549738 LCT 0.032 1.3E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg23851026 chr2:136556271 LCT 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg01986081 chr2:136552499 LCT 0.045 1.4E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT -0.0357897 1.5E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg10019301 chr2:136574079 LCT 0.038 1.5E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg23851026 chr2:136556271 LCT -0.0366992 1.5E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg02668124 chr2:136556590 LCT 0.044 1.5E-05
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg23851026 chr2:136556271 LCT -0.0355829 1.6E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT -0.0355829 1.6E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Ischemic Heart Disease Whole blood Basic model 17483 cg12515326 chr2:136556580 LCT 0.028 1.7E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.035 1.7E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT 0.035 1.7E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 3 14671 cg02668124 chr2:136556590 LCT -0.0434668 1.9E-05
Battram T 27886173 DNA methylation Inflammatory bowel disease Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 240 cg23851026 chr2:136556271 LCT -0.0244 1.9E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT -0.0432721 2E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg19591710 chr2:136558770 LCT -0.0352087 2E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1V0 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.035 2E-05
Gadd DA 35945220 CELA2A protein levels (SeqId = 7140-1) DNA methylation Whole blood SomaScan protein measurement 774 cg24936472 chr2:136555111 LCT -0.62 2E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg10019301 chr2:136574079 LCT 0.23 2.1E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 2 14671 cg02668124 chr2:136556590 LCT 0.043 2.1E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg14667406 chr2:136577303 LCT -0.170837 2.2E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg20242066 chr2:136595261 LCT -0.0357881 2.3E-05
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg04750100 chr2:136595281 LCT -0.00061954 2.3E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg15123519 chr2:136567270 LCT -0.155745 2.4E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg23276673 chr2:136577322 LCT 0.011 2.4E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg15123519 chr2:136567270 LCT -0.0389587 2.5E-05
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT 0.041 2.6E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 3 14671 cg20242066 chr2:136595261 LCT -0.0354545 2.6E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg12515326 chr2:136556580 LCT -0.0411968 2.7E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg23851026 chr2:136556271 LCT -0.0356979 2.7E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT 0.035 2.7E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 2 14671 cg01986081 chr2:136552499 LCT 0.043 2.8E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg10019301 chr2:136574079 LCT 0.22 2.8E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg10019301 chr2:136574079 LCT -0.0344954 2.9E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg23851026 chr2:136556271 LCT -0.0343431 3.2E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg20242066 chr2:136595261 LCT -0.0343368 3.2E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg01986081 chr2:136552499 LCT 0.14 3.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Pain (Self-report) Whole blood Basic model 18413 cg12515326 chr2:136556580 LCT 0.14 3.2E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT 0.034 3.2E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg02668124 chr2:136556590 LCT -0.0420431 3.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Ischemic Heart Disease Whole blood Fully-adjusted model 13797 cg12515326 chr2:136556580 LCT 0.029 3.5E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg23851026 chr2:136556271 LCT 0.035 3.5E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg20242066 chr2:136595261 LCT 0.034 3.7E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg22832131 chr2:136549738 LCT 0.034 3.8E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg23851026 chr2:136556271 LCT 0.034 3.8E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 2 14671 cg19591710 chr2:136558770 LCT -0.0338896 4.1E-05
Bohlin J 27717397 DNA methylation Gestational age Cord blood Ultrasound-estimated gestational age 1068 cg20242066 chr2:136595261 LCT -0.00073926 4.1E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT 0.034 4.2E-05
Suderman M 26953979 DNA methylation 25-Hydroxyvitamin D in pregnancy Cord blood Crude model 1416 cg14667406 chr2:136577303 LCT -2.25e-05 4.2E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg17750252 chr2:136567154 LCT -0.0034 4.2E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg14667406 chr2:136577303 LCT 0.034 4.2E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg12515326 chr2:136556580 LCT 0.04 4.3E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 3 14671 cg15123519 chr2:136567270 LCT 0.037 4.3E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT 0.034 4.3E-05
Battram T 23177740 DNA methylation Age Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279 656 cg20242066 chr2:136595261 LCT 0.00091 4.3E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.034 4.3E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg14667406 chr2:136577303 LCT 0.034 4.4E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 4 14671 cg02668124 chr2:136556590 LCT -0.0451997 4.4E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg15123519 chr2:136567270 LCT 0.038 4.9E-05
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg25344623 chr2:136566232 LCT 1.1 5E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT 0.04 5E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT 0.04 5.1E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg25694820 chr2:136596203 LCT -0.0795197 5.2E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg10019301 chr2:136574079 LCT -0.0359796 5.2E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg20697578 chr2:136545738 LCT -0.0043 5.3E-05
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg20242066 chr2:136595261 LCT 0.0096 5.4E-05
Hoang 34516295 DNA methylation metolachlor whole blood discovery 507 cg02668124 chr2:136556590 LCT -0.01621 5.6E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg20242066 chr2:136595261 LCT 0.039 5.7E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg12515326 chr2:136556580 LCT -0.0395561 5.7E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg10019301 chr2:136574079 LCT 0.033 5.9E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg23276673 chr2:136577322 LCT 0.0025 6.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Fully-adjusted model 14391 cg24936472 chr2:136555111 LCT 0.062 6.2E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg23851026 chr2:136556271 LCT -0.033035 6.3E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.033 6.5E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg15123519 chr2:136567270 LCT 0.033 6.5E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg23851026 chr2:136556271 LCT -0.0339083 6.7E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg23851026 chr2:136556271 LCT -0.0328756 6.8E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg02668124 chr2:136556590 LCT -0.0326965 7.5E-05
Gadd DA 35945220 CCL11 protein levels (SeqId = 5301-7) DNA methylation Whole blood SomaScan protein measurement 774 cg23851026 chr2:136556271 LCT 0.54 7.7E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Pain (Self-report) Whole blood Basic model 18413 cg02668124 chr2:136556590 LCT 0.13 7.8E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg01986081 chr2:136552499 LCT 0.033 7.9E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT 0.032 8.4E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 3 14671 cg19591710 chr2:136558770 LCT 0.032 8.5E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg23851026 chr2:136556271 LCT 0.033 8.7E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg23851026 chr2:136556271 LCT -0.0323888 8.7E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg12515326 chr2:136556580 LCT 0.14 8.8E-05
Gadd DA 35945220 MGAT1 protein levels (SeqId = 10571-14) DNA methylation Whole blood SomaScan protein measurement 774 cg15123519 chr2:136567270 LCT -0.742 9E-05
Gadd DA 35945220 CTRB1 protein levels (SeqId = 5671-1) DNA methylation Whole blood SomaScan protein measurement 774 cg24936472 chr2:136555111 LCT -0.57 9.2E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg02668124 chr2:136556590 LCT 0.13 9.4E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg23851026 chr2:136556271 LCT -0.109054 9.5E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg12515326 chr2:136556580 LCT 0.032 1E-04

 

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