EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for LDLR

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg03554660 chr19:11214666 LDLR -0.0011 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg03567652 chr19:11242272 LDLR -0.0043 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg14331002 chr19:11201349 LDLR -7.6e-05 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg19751789 chr19:11199944 LDLR 0.00064 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg21743867 chr19:11215999 LDLR -0.0017 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg27477601 chr19:11216203 LDLR -0.0014 0E+00
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg22971501 chr19:11199476 LDLR 0.56 9.7E-128
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg21743867 chr19:11215999 LDLR 0.13 3.1E-88
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg07512814 chr19:11203661 LDLR 0.38 2E-84
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg15373972 chr19:11219638 LDLR -0.718896 5.3E-81
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg03567652 chr19:11242272 LDLR NA 5.7E-81
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg12013591 chr19:11199965 LDLR 0.0013 6.6E-78
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg07960944 chr19:11199851 LDLR 0.054 1.8E-75
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg19751789 chr19:11199944 LDLR 0.00075 3.1E-67
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg15373972 chr19:11219638 LDLR -0.68511 6E-67
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19751789 chr19:11199944 LDLR 0.053 9.7E-66
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg22381454 chr19:11199903 LDLR 0.028 1.9E-57
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg03567652 chr19:11242272 LDLR 0.081 4.6E-56
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.129159 1.3E-55
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.136842 2.3E-54
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg19751789 chr19:11199944 LDLR 0.48 5.7E-54
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg10640764 chr19:11216364 LDLR 0.048 3.6E-50
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg07512814 chr19:11203661 LDLR 3.1 5E-50
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.12 7.7E-48
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg19751789 chr19:11199944 LDLR 0.43 1.3E-47
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg10201616 chr19:11198556 LDLR 0.047 7.6E-46
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg15373972 chr19:11219638 LDLR 4.0 1.6E-44
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.114586 4.5E-44
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg10201616 chr19:11198556 LDLR 2.7 6.3E-42
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg12013591 chr19:11199965 LDLR 0.046 6.7E-42
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg26313301 chr19:11219615 LDLR 0.034 8.7E-41
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.106297 3.9E-38
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.106104 5.3E-38
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg17992670 chr19:11216306 LDLR 0.053 6.5E-38
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg03637691 chr19:11202610 LDLR 0.41 1.5E-37
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg19305903 chr19:11203039 LDLR -2.8 9.6E-37
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg03637691 chr19:11202610 LDLR -0.365376 8.8E-35
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR -0.104238 9.7E-35
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg15373972 chr19:11219638 LDLR 0.48 1.1E-34
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg05249393 chr19:11199883 LDLR 0.029 1.6E-34
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg19305903 chr19:11203039 LDLR -0.459664 7.5E-34
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg19305903 chr19:11203039 LDLR -0.075 2.3E-33
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg07512814 chr19:11203661 LDLR -0.016 8.1E-33
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.11 8.3E-33
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg26313301 chr19:11219615 LDLR -0.448776 1.9E-32
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg17992670 chr19:11216306 LDLR -0.547106 3.5E-31
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR 0.095 5.4E-31
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg22971501 chr19:11199476 LDLR 0.3 4.4E-30
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg03637691 chr19:11202610 LDLR -4.3 1.1E-29
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg05249393 chr19:11199883 LDLR 0.00072 1.3E-29
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg18596381 chr19:11199917 LDLR 0.023 1.8E-29
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg22971501 chr19:11199476 LDLR 0.31 3.1E-29
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR -0.100919 5.8E-29
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg03637691 chr19:11202610 LDLR 0.32 3.3E-28
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR -0.090111 7.8E-28
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg15373972 chr19:11219638 LDLR 0.42 2.2E-27
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg12013591 chr19:11199965 LDLR 0.47 2.5E-27
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg23943360 chr19:11200146 LDLR 0.00024 7.1E-27
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.095 8.3E-27
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg00919002 chr19:11201619 LDLR 0.019 7.7E-26
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg13351962 chr19:11200983 LDLR 0.015 7.8E-26
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR 0.092 2.3E-25
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg17992670 chr19:11216306 LDLR 0.5 6.3E-25
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg26849535 chr19:11199222 LDLR 0.36 6.6E-25
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg06950392 chr19:11213564 LDLR NA 9.8E-25
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg19305903 chr19:11203039 LDLR -0.385063 4.1E-24
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg22006489 chr19:11207145 LDLR -0.321372 4.2E-24
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR 0.084 4.9E-24
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg26849535 chr19:11199222 LDLR 0.36 6.6E-24
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg22971501 chr19:11199476 LDLR 1.4 7.9E-24
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg03637691 chr19:11202610 LDLR 0.13 8.1E-24
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR 0.084 8.2E-24
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0824368 1.5E-23
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.081 5.5E-23
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR 0.081 6.4E-23
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg17992670 chr19:11216306 LDLR -0.480847 8.4E-23
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.087 1.2E-22
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.0916006 1.5E-22
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg03637691 chr19:11202610 LDLR -0.288997 2.2E-22
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg07960944 chr19:11199851 LDLR 0.28 2.6E-22
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR -0.0798854 3.3E-22
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg26313301 chr19:11219615 LDLR 3.6 3.9E-22
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg26313301 chr19:11219615 LDLR 0.00077 5.5E-22
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg05249393 chr19:11199883 LDLR NA 6.1E-22
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg15373972 chr19:11219638 LDLR 0.37 8.1E-22
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg15373972 chr19:11219638 LDLR 0.39 9.7E-22
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg07960944 chr19:11199851 LDLR 0.27 1.5E-21
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR 0.082 2.1E-21
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg03637691 chr19:11202610 LDLR -0.282991 2.1E-21
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg21743867 chr19:11215999 LDLR 0.0018 2.8E-21
Nones K 24500968 DNA methylation Pancreatic ductal adenocarcinoma Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata - 196 cg10201616 chr19:11198556 LDLR NA 3.8E-21
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR 0.077 9E-21
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg26313301 chr19:11219615 LDLR 0.36 2.9E-20
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.0866272 3.2E-20
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg26313301 chr19:11219615 LDLR -0.368927 6.6E-20
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR 0.078 6.8E-20
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR 0.074 9.7E-20
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 3821015 (gene symbol: LDLR) Whole blood Meta-analysis 4170 cg19751789 chr19:11199944 LDLR NA 2E-19
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.074 2.5E-19
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg03637691 chr19:11202610 LDLR -0.12 3.4E-19
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg13743731 chr19:11204447 LDLR 0.023 7.8E-19
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg17992670 chr19:11216306 LDLR 0.43 8E-19
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR 0.072 1.5E-18
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR -0.0720322 2.4E-18
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg05249393 chr19:11199883 LDLR 0.27 2.5E-18
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg07512814 chr19:11203661 LDLR -0.042 2.7E-18
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg12013591 chr19:11199965 LDLR 0.0031 2.7E-18
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg17992670 chr19:11216306 LDLR 0.073 3.7E-18
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR 0.071 4.9E-18
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.076 8.9E-18
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg26313301 chr19:11219615 LDLR -0.20131 1.4E-17
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0702842 1.6E-17
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg05249393 chr19:11199883 LDLR 0.25 2.2E-17
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.07 2.8E-17
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR 0.07 4.4E-17
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg12013591 chr19:11199965 LDLR 0.31 4.8E-17
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg12013591 chr19:11199965 LDLR 0.31 4.9E-17
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg07960944 chr19:11199851 LDLR 0.07 6E-17
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg26313301 chr19:11219615 LDLR 0.33 8.4E-17
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg15373972 chr19:11219638 LDLR 0.34 8.5E-17
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg07960944 chr19:11199851 LDLR 0.073 9.6E-17
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR 0.068 1.1E-16
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg26313301 chr19:11219615 LDLR 0.32 1.7E-16
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR -0.0709254 2.1E-16
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR -0.0782646 2.7E-16
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR -0.0670004 3.2E-16
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg26313301 chr19:11219615 LDLR -0.00067 4.4E-16
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0720797 4.5E-16
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR 0.07 4.5E-16
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg22381454 chr19:11199903 LDLR 0.26 5.2E-16
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg22971501 chr19:11199476 LDLR 0.22 5.2E-16
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.075441 6.5E-16
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR 0.07 8.6E-16
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg19751789 chr19:11199944 LDLR -0.11 8.7E-16
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg17992670 chr19:11216306 LDLR -0.0672266 9.4E-16
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR -0.0661323 1.1E-15
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR -0.0654395 2.1E-15
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg18596381 chr19:11199917 LDLR 0.22 2.2E-15
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0702044 2.2E-15
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg19305903 chr19:11203039 LDLR -0.299808 2.6E-15
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg22971501 chr19:11199476 LDLR 0.21 4.2E-15
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.074 5.5E-15
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.087 5.7E-15
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg17992670 chr19:11216306 LDLR 3.1 5.7E-15
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg06950392 chr19:11213564 LDLR -0.345141 6.6E-15
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR 0.086 8.8E-15
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg22381454 chr19:11199903 LDLR 0.23 9.3E-15
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0638348 1E-14
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg12013591 chr19:11199965 LDLR 0.063 1E-14
Dugue PA 31552803 DNA methylation Smoking Whole blood Current vs never smoking 1851 cg07512814 chr19:11203661 LDLR -0.17 1.2E-14
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR 0.064 1.2E-14
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg19305903 chr19:11203039 LDLR -0.13 1.3E-14
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR -0.0632148 1.3E-14
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR -0.0861086 1.7E-14
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg19305903 chr19:11203039 LDLR 0.28 1.7E-14
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR 0.063 1.8E-14
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR 0.063 1.9E-14
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR -0.0631598 1.9E-14
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg17992670 chr19:11216306 LDLR 0.17 2.3E-14
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.0717571 2.9E-14
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.063 3.2E-14
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg17992670 chr19:11216306 LDLR 0.063 4.5E-14
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg17992670 chr19:11216306 LDLR 0.38 4.8E-14
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR -0.0625973 5.1E-14
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg22381454 chr19:11199903 LDLR 0.062 6.7E-14
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg22971501 chr19:11199476 LDLR 0.0021 6.8E-14
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR -0.0665777 8.6E-14
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg17992670 chr19:11216306 LDLR 0.062 8.7E-14
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR 0.061 1E-13
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg15373972 chr19:11219638 LDLR 0.13 1.1E-13
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg22006489 chr19:11207145 LDLR -0.0757573 1.2E-13
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR -0.0817568 1.3E-13
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR 0.06 1.3E-13
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR 0.063 1.4E-13
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0655431 1.5E-13
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0655171 1.5E-13
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg07960944 chr19:11199851 LDLR 0.06 1.7E-13
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR -0.0607136 1.8E-13
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg02630186 chr19:11205800 LDLR -0.232412 2E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg07960944 chr19:11199851 LDLR 0.00068 2E-13
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.061 2.2E-13
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg18596381 chr19:11199917 LDLR 0.19 2.4E-13
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.064 2.4E-13
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg19751789 chr19:11199944 LDLR -0.11 2.6E-13
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg08826460 chr19:11201433 LDLR -2.131393 3E-13
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR -0.08172 3.1E-13
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg22381454 chr19:11199903 LDLR 0.06 3.1E-13
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg22381454 chr19:11199903 LDLR 0.06 3.6E-13
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR -0.0807888 3.9E-13
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg06950392 chr19:11213564 LDLR -0.331848 4.8E-13
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg22378492 chr19:11202486 LDLR 0.23 5.1E-13
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0595286 5.3E-13
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR -0.0595047 5.5E-13
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg19305903 chr19:11203039 LDLR 0.33 5.5E-13
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR 0.06 9.1E-13
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg22378492 chr19:11202486 LDLR 0.066 9.3E-13
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg26849535 chr19:11199222 LDLR 0.25 1.2E-12
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg07960944 chr19:11199851 LDLR -5.7 1.2E-12
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg22381454 chr19:11199903 LDLR 0.064 1.3E-12
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.058494 1.3E-12
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg06950392 chr19:11213564 LDLR -0.322884 1.7E-12
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg22378492 chr19:11202486 LDLR 0.23 1.7E-12
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg03637691 chr19:11202610 LDLR 0.2 1.9E-12
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg19751789 chr19:11199944 LDLR 0.21 2.4E-12
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg15373972 chr19:11219638 LDLR 2.1 3.4E-12
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg22378492 chr19:11202486 LDLR 0.067 3.5E-12
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0567788 5.9E-12
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg07960944 chr19:11199851 LDLR 0.059 6.4E-12
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR 0.057 7.7E-12
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR -0.0755023 9.8E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR -0.0760314 1.1E-11
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg17992670 chr19:11216306 LDLR 0.057 1.2E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg12013591 chr19:11199965 LDLR 0.066 1.3E-11
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0557674 1.4E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg26849535 chr19:11199222 LDLR 0.058 1.4E-11
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg17992670 chr19:11216306 LDLR 0.34 1.4E-11
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg26849535 chr19:11199222 LDLR -0.11 1.5E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg05249393 chr19:11199883 LDLR 0.054 1.6E-11
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR 0.056 1.6E-11
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR 0.055 1.8E-11
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.0554203 1.9E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR -0.0568773 2.1E-11
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR -0.0577074 2.1E-11
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg15373972 chr19:11219638 LDLR 0.27 2.8E-11
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR -0.0542131 2.9E-11
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR -0.0589461 2.9E-11
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.074 3.4E-11
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR -0.0561436 4.2E-11
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg19305903 chr19:11203039 LDLR -0.049 4.5E-11
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg20196790 chr19:11231222 LDLR -0.306486 4.5E-11
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.057 4.7E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR 0.057 5.9E-11
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.062 5.9E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR -0.0613654 6E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg05249393 chr19:11199883 LDLR 0.054 6.3E-11
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg17992670 chr19:11216306 LDLR 0.32 6.7E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR -0.0538335 6.8E-11
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR 0.054 7.6E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg05249393 chr19:11199883 LDLR 0.054 8.2E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR -0.053657 9E-11
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR 0.055 9.1E-11
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg06950392 chr19:11213564 LDLR 5.1 9.3E-11
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg22971501 chr19:11199476 LDLR 0.053 9.5E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR 0.053 1E-10
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.057 1E-10
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg22378492 chr19:11202486 LDLR 0.06 1.1E-10
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg19751789 chr19:11199944 LDLR -3.9 1.1E-10
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.053 1.2E-10
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0530847 1.2E-10
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR -0.0526494 1.4E-10
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR -0.053813 1.4E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg17992670 chr19:11216306 LDLR -0.00068 1.4E-10
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg22006489 chr19:11207145 LDLR 0.018 1.4E-10
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg26849535 chr19:11199222 LDLR 0.054 1.4E-10
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.072 1.5E-10
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg07960944 chr19:11199851 LDLR 0.013 1.5E-10
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.06 1.6E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg17992670 chr19:11216306 LDLR -0.0527439 1.6E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR 0.052 1.7E-10
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR 0.053 1.7E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg26849535 chr19:11199222 LDLR 0.054 1.8E-10
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.06 2E-10
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.0599365 2E-10
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR 0.078 2.1E-10
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR 0.055 2.2E-10
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR -0.0548899 2.3E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.06 2.4E-10
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg06950392 chr19:11213564 LDLR 0.0099 2.4E-10
Zeilinger S 23691101 DNA methylation Smoking Whole blood Current vs never smoking discovery 1011 cg07512814 chr19:11203661 LDLR NA 2.6E-10
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR 0.052 2.7E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR 0.05 2.7E-10
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR -0.0519107 3.1E-10
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR -0.0518862 3.2E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg24113439 chr19:11216129 LDLR -0.00087 3.5E-10
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.052 3.6E-10
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg05249393 chr19:11199883 LDLR 0.051 4.8E-10
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg07960944 chr19:11199851 LDLR -0.0506931 5E-10
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR 0.051 5E-10
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg05249393 chr19:11199883 LDLR 0.014 5.2E-10
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR -0.0512053 5.4E-10
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg06950392 chr19:11213564 LDLR -0.273725 5.5E-10
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.051 6E-10
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0548966 6E-10
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0547523 6.3E-10
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg03637691 chr19:11202610 LDLR -0.037 6.4E-10
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg07960944 chr19:11199851 LDLR -0.031 7.5E-10
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR 0.054 7.8E-10
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR -0.0506709 8.2E-10
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg19305903 chr19:11203039 LDLR -0.288387 8.3E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg22006489 chr19:11207145 LDLR -0.0506277 8.5E-10
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg12013591 chr19:11199965 LDLR -0.11 8.6E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg24113439 chr19:11216129 LDLR 0.001 8.8E-10
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg17992670 chr19:11216306 LDLR 0.05 9.6E-10
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg07512814 chr19:11203661 LDLR -0.5846016 1E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg12013591 chr19:11199965 LDLR 0.061 1E-09
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 4 14671 cg07960944 chr19:11199851 LDLR 0.053 1E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.05 1E-09
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.050276 1.1E-09
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg26849535 chr19:11199222 LDLR 0.21 1.2E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR -0.0501483 1.2E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR 0.052 1.3E-09
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg26849535 chr19:11199222 LDLR 0.05 1.3E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg12013591 chr19:11199965 LDLR 0.052 1.5E-09
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg12013591 chr19:11199965 LDLR -2.6 1.6E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg15373972 chr19:11219638 LDLR 0.048 1.7E-09
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR 0.052 1.7E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg13743731 chr19:11204447 LDLR -0.00093 1.8E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR -0.0510911 1.8E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR -0.0494414 2.1E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg13743731 chr19:11204447 LDLR -0.0061 2.1E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg12013591 chr19:11199965 LDLR -0.0501799 2.2E-09
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg17992670 chr19:11216306 LDLR 0.049 2.3E-09
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.0492158 2.5E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg05249393 chr19:11199883 LDLR 0.049 2.5E-09
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg02630186 chr19:11205800 LDLR -0.188621 2.7E-09
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.053 2.7E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg05249393 chr19:11199883 LDLR 0.049 2.8E-09
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR -0.0490357 2.8E-09
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR 0.049 3E-09
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg12013591 chr19:11199965 LDLR 0.056 3E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg03637691 chr19:11202610 LDLR -0.085 3E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg03637691 chr19:11202610 LDLR -0.03 3.1E-09
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR 0.054 3.1E-09
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg22381454 chr19:11199903 LDLR 0.049 3.2E-09
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR -0.0486231 3.5E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg19751789 chr19:11199944 LDLR -0.031 3.7E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR 0.051 3.8E-09
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR 0.049 3.9E-09
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.052 4E-09
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR -0.0485002 4E-09
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR -0.0660757 4.1E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg22971501 chr19:11199476 LDLR 0.051 4.8E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg10640764 chr19:11216364 LDLR -0.00067 4.8E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg18596381 chr19:11199917 LDLR -0.00039 4.8E-09
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg26849535 chr19:11199222 LDLR 0.048 4.9E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR 0.05 5E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.055 5.3E-09
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR 0.048 5.4E-09
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.052 5.7E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg05249393 chr19:11199883 LDLR 0.05 5.8E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg05249393 chr19:11199883 LDLR 0.048 6.1E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR 0.048 6.1E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR 0.05 6.1E-09
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg22971501 chr19:11199476 LDLR 0.048 6.2E-09
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR -0.0478693 6.6E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.048 7.4E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR 0.048 7.5E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.065 7.5E-09
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg15373972 chr19:11219638 LDLR -0.230352 7.9E-09
Battram T 27886173 DNA methylation Crohn's disease Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 161 cg19751789 chr19:11199944 LDLR 0.022 8E-09
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg12013591 chr19:11199965 LDLR 0.048 8.2E-09
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR -0.0673933 8.4E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR 0.055 8.5E-09
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR -0.0490121 8.9E-09
Hedman AK 28213390 DNA methylation Serum high-density lipoprotein cholesterol Whole blood Discovery and replication 3889 cg17992670 chr19:11216306 LDLR -0.0001337 9.1E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR 0.055 9.1E-09
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.065 9.2E-09
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR 0.05 9.6E-09
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR -0.0645462 9.6E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg06950392 chr19:11213564 LDLR -0.00055 9.7E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR -0.0473621 9.9E-09
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0472998 9.9E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0472533 1E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR -0.0679999 1.1E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR -0.0542832 1.3E-08
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg07512814 chr19:11203661 LDLR 0.051 1.3E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg19751789 chr19:11199944 LDLR 0.0015 1.3E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Pain (Self-report) Whole blood Basic model 18413 cg19305903 chr19:11203039 LDLR -0.21 1.3E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR -0.0475407 1.3E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR -0.0462078 1.4E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR 0.047 1.4E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.063 1.5E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.0467227 1.5E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg03637691 chr19:11202610 LDLR -0.184616 1.8E-08
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR 0.046 1.8E-08
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR -0.0463523 1.9E-08
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR -0.0463048 2E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR 0.046 2E-08
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR -0.0462462 2.1E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg26313301 chr19:11219615 LDLR 0.23 2.1E-08
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0462101 2.1E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg05249393 chr19:11199883 LDLR -0.00041 2.2E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg26313301 chr19:11219615 LDLR -0.0462396 2.3E-08
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR -0.048359 2.4E-08
Walker R 33397400 DNA methylation APOE e2 vs e4 Whole blood Meta-analysis 3587 cg19751789 chr19:11199944 LDLR -0.034 2.4E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg12013591 chr19:11199965 LDLR 0.24 2.4E-08
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg17992670 chr19:11216306 LDLR -0.273917 2.4E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR 0.046 2.5E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg07512814 chr19:11203661 LDLR -0.170394 2.5E-08
Ma J 32525743 DNA methylation Healthy eating Whole blood, CD4+ T-cells, CD14+ monocytes Trans-ethnic meta-analysis 9724 cg19751789 chr19:11199944 LDLR 0.001 2.5E-08
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg27477601 chr19:11216203 LDLR 0.012 2.6E-08
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg07512814 chr19:11203661 LDLR 0.046 2.7E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0458585 2.7E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR -0.0516006 2.9E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR 0.047 3.2E-08
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.046 3.2E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg15373972 chr19:11219638 LDLR 0.1 3.2E-08
Braun KVE 28194238 DNA methylation High-density lipoprotein cholesterol Whole blood Discovery and replication 1485 cg26313301 chr19:11219615 LDLR -0.0056 3.3E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg08826460 chr19:11201433 LDLR 0.0007 3.3E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg17992670 chr19:11216306 LDLR 0.047 3.3E-08
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg26313301 chr19:11219615 LDLR 0.23 3.3E-08
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR -0.0521027 3.5E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg26849535 chr19:11199222 LDLR 0.047 3.5E-08
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR 0.046 3.5E-08
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg06950392 chr19:11213564 LDLR -0.0474992 3.6E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg19305903 chr19:11203039 LDLR -0.1 3.7E-08
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg17992670 chr19:11216306 LDLR 0.044 3.9E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg26313301 chr19:11219615 LDLR 0.046 3.9E-08
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.052 4E-08
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR 0.046 4.1E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg07411449 chr19:11231029 LDLR -0.218494 4.1E-08
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg26849535 chr19:11199222 LDLR -0.0461944 4.2E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg22971501 chr19:11199476 LDLR -0.069 4.4E-08
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg06950392 chr19:11213564 LDLR -0.0452914 4.5E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR 0.045 4.5E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg12013591 chr19:11199965 LDLR -0.213269 4.6E-08
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg22006489 chr19:11207145 LDLR 0.18 4.7E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR 0.045 4.8E-08
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR -0.0451456 4.8E-08
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR 0.045 5.1E-08
Li M 33279932 DNA methylation Schizophrenia Whole blood main 999 cg10640764 chr19:11216364 LDLR -0.00561 5.1E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR -0.0449527 5.1E-08
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR 0.046 5.6E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.0503049 5.7E-08
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR -0.0470729 5.8E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR -0.0497744 6.1E-08
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg15373972 chr19:11219638 LDLR -0.204402 6.3E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg26849535 chr19:11199222 LDLR -0.045435 6.4E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg21743867 chr19:11215999 LDLR 0.0051 6.5E-08
Hedman AK 28213390 DNA methylation Serum high-density lipoprotein cholesterol Whole blood Discovery 2306 cg26313301 chr19:11219615 LDLR -0.0001303 6.8E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg22381454 chr19:11199903 LDLR 0.047 7E-08
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg03567652 chr19:11242272 LDLR -0.0444513 7.2E-08
Guida F 25556184 DNA methylation Smoking Whole blood Current vs never smoking 582 cg07512814 chr19:11203661 LDLR -0.18 7.4E-08
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR 0.044 7.4E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR 0.044 7.7E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR -0.0439891 8.1E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg22006489 chr19:11207145 LDLR 0.17 8.2E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg17992670 chr19:11216306 LDLR -0.0450346 8.2E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg12013591 chr19:11199965 LDLR 0.00052 8.7E-08
Hedman AK 28213390 DNA methylation Serum high-density lipoprotein cholesterol Whole blood Discovery 2306 cg17992670 chr19:11216306 LDLR -0.0001435 9E-08
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg26849535 chr19:11199222 LDLR -0.0451134 9.3E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.044053 9.4E-08
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0440287 9.6E-08
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.044 9.6E-08
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.044 1E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg07960944 chr19:11199851 LDLR 0.044 1E-07
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR 0.044 1E-07
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR 0.044 1.1E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR 0.06 1.1E-07
Li M 33279932 DNA methylation Schizophrenia Whole blood adjusted for cell composition 999 cg10640764 chr19:11216364 LDLR NA 1.1E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR 0.047 1.1E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR 0.046 1.2E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Lung Cancer Whole blood Basic model 18364 cg19305903 chr19:11203039 LDLR -0.018 1.2E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR 0.044 1.2E-07
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg26849535 chr19:11199222 LDLR 0.045 1.3E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR 0.044 1.3E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg22971501 chr19:11199476 LDLR 0.045 1.4E-07
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.043 1.4E-07
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg02630186 chr19:11205800 LDLR -0.1665 1.4E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg03637691 chr19:11202610 LDLR -0.076 1.4E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR 0.044 1.4E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg17992670 chr19:11216306 LDLR -0.0422121 1.4E-07
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.043 1.4E-07
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg26849535 chr19:11199222 LDLR 0.045 1.5E-07
Darina Czamara 38600394 DNA methylation sex placenta meta-analysis of robust linear regression results per cohort 746 cg19751789 chr19:11199944 LDLR -0.2081009 1.6E-07
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR -0.0432172 1.6E-07
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg18596381 chr19:11199917 LDLR 0.043 1.7E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg27477601 chr19:11216203 LDLR 0.00095 1.7E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg06950392 chr19:11213564 LDLR -0.0431491 1.7E-07
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.046 1.7E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg18596381 chr19:11199917 LDLR 0.043 1.8E-07
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.043 1.8E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg03567652 chr19:11242272 LDLR 0.043 1.8E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR -0.0450192 2E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg19751789 chr19:11199944 LDLR -0.076 2E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg22381454 chr19:11199903 LDLR -0.033 2E-07
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg06950392 chr19:11213564 LDLR -0.0429001 2E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg03567652 chr19:11242272 LDLR -0.159484 2E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0428438 2.1E-07
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.0489097 2.1E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg22381454 chr19:11199903 LDLR 0.042 2.1E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg06950392 chr19:11213564 LDLR 0.24 2.2E-07
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR 0.043 2.2E-07
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg22381454 chr19:11199903 LDLR -2.5 2.3E-07
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg22971501 chr19:11199476 LDLR -1.2 2.3E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg19305903 chr19:11203039 LDLR -0.091 2.3E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0458508 2.3E-07
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0426365 2.4E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg26849535 chr19:11199222 LDLR 0.042 2.6E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR -0.0616927 2.6E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg26849535 chr19:11199222 LDLR -0.0438616 2.6E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR 0.043 2.7E-07
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR -0.0620443 2.8E-07
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0423282 2.9E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR 0.043 3E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg22381454 chr19:11199903 LDLR -0.0422546 3.1E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg17992670 chr19:11216306 LDLR -0.0429735 3.1E-07
Christiansen C 33593402 DNA methylation Smoking Whole blood Current vs never smoking meta-analysis in European samples 912 cg19305903 chr19:11203039 LDLR NA 3.2E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg22381454 chr19:11199903 LDLR -0.0421545 3.3E-07
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg26849535 chr19:11199222 LDLR 0.045 3.3E-07
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg19751789 chr19:11199944 LDLR -0.00322 3.3E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg12013591 chr19:11199965 LDLR -0.093 3.4E-07
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg17992670 chr19:11216306 LDLR 0.26 3.5E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg22381454 chr19:11199903 LDLR -0.0420227 3.5E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg19751789 chr19:11199944 LDLR 0.16 3.6E-07
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg22971501 chr19:11199476 LDLR 0.042 3.6E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR -0.0439539 3.7E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR 0.043 3.7E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.057 3.7E-07
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg17992670 chr19:11216306 LDLR 0.039 3.7E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR -0.041925 3.8E-07
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR -0.0418291 4E-07
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.042 4.1E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR 0.047 4.1E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg22971501 chr19:11199476 LDLR -0.0422302 4.1E-07
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg18596381 chr19:11199917 LDLR -1.163705 4.3E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg02630186 chr19:11205800 LDLR 0.042 4.3E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR -0.042329 4.4E-07
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR 0.044 4.5E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg22381454 chr19:11199903 LDLR -0.00017 4.7E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg26849535 chr19:11199222 LDLR -0.031 4.7E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg06950392 chr19:11213564 LDLR 0.042 4.7E-07
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg02630186 chr19:11205800 LDLR -4.2 4.8E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Fully-adjusted model 14391 cg19751789 chr19:11199944 LDLR -0.079 4.9E-07
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.042 4.9E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg26313301 chr19:11219615 LDLR 0.044 5.1E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg19305903 chr19:11203039 LDLR -0.055 5.2E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg23943360 chr19:11200146 LDLR 0.00012 5.3E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg26849535 chr19:11199222 LDLR 0.043 5.6E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg26849535 chr19:11199222 LDLR -0.0420171 5.7E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR 0.046 5.8E-07
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0443695 5.8E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Kidney Disease (Estimated) Whole blood Basic model 18318 cg03637691 chr19:11202610 LDLR -0.05 5.9E-07
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg26849535 chr19:11199222 LDLR 0.041 5.9E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.0411478 6.2E-07
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg22006489 chr19:11207145 LDLR -0.129149 6.2E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR 0.041 6.2E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR 0.047 6.3E-07
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg23943360 chr19:11200146 LDLR 0.0075 6.4E-07
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg26313301 chr19:11219615 LDLR 0.21 6.5E-07
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg07512814 chr19:11203661 LDLR -0.0174 6.7E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg22971501 chr19:11199476 LDLR 0.041 6.8E-07
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR 0.041 6.9E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR -0.0408205 6.9E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg03567652 chr19:11242272 LDLR -0.0408277 7.5E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg06950392 chr19:11213564 LDLR 0.041 7.5E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg02630186 chr19:11205800 LDLR 0.15 7.6E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg06950392 chr19:11213564 LDLR 0.002 7.6E-07
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.047 7.7E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR -0.0556918 7.7E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR -0.0407181 8.1E-07
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0436247 8.5E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg22381454 chr19:11199903 LDLR 0.041 8.7E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg07960944 chr19:11199851 LDLR -0.0418033 8.9E-07
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg22006489 chr19:11207145 LDLR -0.0531016 8.9E-07
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg18596381 chr19:11199917 LDLR 0.041 9E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR -0.0580642 9.1E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg17992670 chr19:11216306 LDLR 0.041 9.2E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR 0.041 9.2E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg07960944 chr19:11199851 LDLR -0.064 9.3E-07
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.0462284 9.4E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg22381454 chr19:11199903 LDLR 0.04 9.4E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg12013591 chr19:11199965 LDLR -0.0476811 9.5E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg23943360 chr19:11200146 LDLR 0.16 9.6E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg26849535 chr19:11199222 LDLR -0.0404351 9.6E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0403935 9.9E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.055 9.9E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR 0.042 1E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg19305903 chr19:11203039 LDLR -0.231126 1E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR 0.04 1E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR -0.0403187 1E-06
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg12876142 chr19:11227689 LDLR 0.24 1.1E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR -0.0407152 1.1E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg22381454 chr19:11199903 LDLR -0.0402795 1.1E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg22381454 chr19:11199903 LDLR -0.0403281 1.1E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR 0.041 1.1E-06
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR 0.04 1.1E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR -0.0410738 1.2E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg13351962 chr19:11200983 LDLR 0.041 1.2E-06
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR 0.055 1.2E-06
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 1 14671 cg26849535 chr19:11199222 LDLR -0.0400563 1.2E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.046 1.3E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg03637691 chr19:11202610 LDLR -0.0638912 1.3E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg06950392 chr19:11213564 LDLR 0.04 1.3E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR 0.042 1.4E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR 0.04 1.4E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg23943360 chr19:11200146 LDLR 0.00066 1.4E-06
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR -0.0398103 1.4E-06
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg20196790 chr19:11231222 LDLR 0.23 1.4E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg07512814 chr19:11203661 LDLR -0.04334 1.5E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg26313301 chr19:11219615 LDLR -0.0421103 1.5E-06
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.045 1.5E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.054 1.5E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR 0.039 1.5E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.0452723 1.5E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg07960944 chr19:11199851 LDLR 0.14 1.6E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR -0.0396504 1.6E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.04 1.6E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR 0.04 1.6E-06
Kazmi N 31230546 DNA methylation Hypertensive disorders of pregnancy Cord blood Meta analysis unadjusted model 5242 cg07512814 chr19:11203661 LDLR 0.014 1.6E-06
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg13743731 chr19:11204447 LDLR -1.349525 1.6E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.04 1.6E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR -0.0526585 1.7E-06
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0425465 1.7E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR 0.04 1.7E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg22378492 chr19:11202486 LDLR -0.044353 1.7E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg10201616 chr19:11198556 LDLR -0.00061 1.7E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg17992670 chr19:11216306 LDLR -0.0394953 1.7E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.054 1.7E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg17992670 chr19:11216306 LDLR 0.04 1.8E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR -0.039387 1.8E-06
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR -0.0393649 1.8E-06
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0393512 1.9E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR -0.0422094 1.9E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR 0.039 2E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg02630186 chr19:11205800 LDLR 0.039 2E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.053 2E-06
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR -0.0394595 2.1E-06
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.042 2.1E-06
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR 0.039 2.1E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Osteoarthritis (Self-report) Whole blood Basic model 18060 cg17992670 chr19:11216306 LDLR 0.15 2.1E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg03567652 chr19:11242272 LDLR -0.0419522 2.1E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0419535 2.2E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 3 14671 cg18596381 chr19:11199917 LDLR 0.039 2.2E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg22006489 chr19:11207145 LDLR 0.039 2.2E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg23943360 chr19:11200146 LDLR 0.041 2.3E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR 0.04 2.3E-06
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg18596381 chr19:11199917 LDLR 0.039 2.4E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg12013591 chr19:11199965 LDLR -0.0394318 2.5E-06
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR -0.0413383 2.6E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR 0.039 2.6E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR 0.04 2.6E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR 0.041 2.6E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR 0.041 2.7E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg18596381 chr19:11199917 LDLR 0.041 2.8E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR -0.039948 2.9E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR -0.0391762 2.9E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg02630186 chr19:11205800 LDLR 0.039 2.9E-06
Darina Czamara 38600394 DNA methylation sex placenta meta-analysis of robust linear regression results per cohort 746 cg22381454 chr19:11199903 LDLR -0.2101252 3E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR 0.039 3E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg23943360 chr19:11200146 LDLR 0.04 3E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg05249393 chr19:11199883 LDLR -0.0378626 3.1E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg26313301 chr19:11219615 LDLR 0.037 3.2E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR 0.038 3.2E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR -0.0384203 3.2E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg22006489 chr19:11207145 LDLR -0.0373351 3.3E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR 0.038 3.3E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR 0.052 3.4E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg02630186 chr19:11205800 LDLR 0.038 3.4E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg27477601 chr19:11216203 LDLR 0.0032 3.4E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR -0.0383208 3.4E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR 0.038 3.5E-06
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg07512814 chr19:11203661 LDLR -0.417573 3.5E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg22971501 chr19:11199476 LDLR -0.0382683 3.5E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg18596381 chr19:11199917 LDLR 0.038 3.7E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg26313301 chr19:11219615 LDLR 0.039 3.7E-06
Hedman AK 28213390 DNA methylation Serum high-density lipoprotein cholesterol Whole blood Discovery and replication 3889 cg26313301 chr19:11219615 LDLR -9.41e-05 3.8E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR -0.0380594 4E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg02630186 chr19:11205800 LDLR 0.038 4.1E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg06950392 chr19:11213564 LDLR 0.037 4.1E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg22378492 chr19:11202486 LDLR -0.042574 4.2E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg02630186 chr19:11205800 LDLR 0.038 4.3E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg17992670 chr19:11216306 LDLR -0.0384305 4.4E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg22971501 chr19:11199476 LDLR -0.0389004 4.4E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg22006489 chr19:11207145 LDLR -0.119295 4.4E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg06170501 chr19:11211207 LDLR -0.192511 4.5E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR 0.039 4.6E-06
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg06950392 chr19:11213564 LDLR 0.21 4.6E-06
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR -0.0555977 4.6E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg03567652 chr19:11242272 LDLR -0.0377499 4.8E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg18596381 chr19:11199917 LDLR -0.0372496 4.8E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg06950392 chr19:11213564 LDLR -0.0360331 4.8E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg26849535 chr19:11199222 LDLR -0.0395925 4.8E-06
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.043 4.9E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg22381454 chr19:11199903 LDLR 0.14 4.9E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR 0.038 5E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg23943360 chr19:11200146 LDLR 0.039 5.2E-06
Gadd DA 35945220 CPOX protein levels (SeqId = 18241-18) DNA methylation Whole blood SomaScan protein measurement 774 cg03567652 chr19:11242272 LDLR -0.71 5.3E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Lung Cancer Whole blood Basic model 18364 cg07512814 chr19:11203661 LDLR -0.012 5.3E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0375593 5.4E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg07960944 chr19:11199851 LDLR -0.0370576 5.4E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR -0.0388323 5.5E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg18596381 chr19:11199917 LDLR -0.0374808 5.6E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg26849535 chr19:11199222 LDLR -0.076 5.6E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg18596381 chr19:11199917 LDLR -0.0374772 5.6E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.0374676 5.6E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR -0.0388736 5.7E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg03567652 chr19:11242272 LDLR -0.037434 5.8E-06
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg12876142 chr19:11227689 LDLR 0.24 5.9E-06
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 4 14671 cg22006489 chr19:11207145 LDLR -0.0485082 6E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0400289 6E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 3 14671 cg26313301 chr19:11219615 LDLR 0.039 6.3E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR 0.037 6.4E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR -0.0372399 6.4E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg18596381 chr19:11199917 LDLR -0.0372913 6.6E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR -0.0371786 6.7E-06
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR -0.0375846 6.8E-06
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.0371374 6.8E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR 0.042 6.9E-06
Zhao N 34008478 lung cancer DNA methylation whole blood None 430 cg19305903 chr19:11203039 LDLR 0.14 7.3E-06
Gadd DA 35945220 TFF1 protein levels (SeqId = 9185-15) DNA methylation Whole blood SomaScan protein measurement 774 cg07960944 chr19:11199851 LDLR -0.692 7.4E-06
Battram T 23177740 DNA methylation Age Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279 656 cg12013591 chr19:11199965 LDLR 0.00028 7.4E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg07960944 chr19:11199851 LDLR -0.0366352 7.4E-06
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR 0.055 7.4E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR -0.0351326 7.5E-06
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0369643 7.5E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR 0.037 7.5E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg22381454 chr19:11199903 LDLR 0.037 7.8E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg05249393 chr19:11199883 LDLR -0.036308 7.8E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR 0.041 7.9E-06
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR -0.0426599 7.9E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR -0.0384537 8E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg22006489 chr19:11207145 LDLR -0.0375104 8.1E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR -0.0494306 8.1E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR 0.037 8.2E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR -0.0372309 8.3E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0367922 8.3E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR -0.0374285 8.3E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR -0.0411991 8.4E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg05249393 chr19:11199883 LDLR -0.0360935 8.4E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 3 14671 cg23943360 chr19:11200146 LDLR 0.038 8.4E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR -0.0367431 8.5E-06
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR -0.0502877 8.6E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg11556884 chr19:11224442 LDLR -0.139729 8.6E-06
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg18596381 chr19:11199917 LDLR 0.037 8.7E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg26849535 chr19:11199222 LDLR 0.038 8.7E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 2 14671 cg23943360 chr19:11200146 LDLR 0.038 8.8E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg06950392 chr19:11213564 LDLR 0.2 8.8E-06
Ambatipudi S 26864933 DNA methylation Smoking Peripheral blood Former vs never smoking 717 cg07512814 chr19:11203661 LDLR NA 8.9E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 3 14671 cg08483713 chr19:11241669 LDLR 0.042 9E-06
Liu J 31197173 DNA methylation fasting insulin whole blood Base 4808 cg22381454 chr19:11199903 LDLR -3.2 9.1E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg17992670 chr19:11216306 LDLR -0.0366227 9.1E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg18596381 chr19:11199917 LDLR -0.021 9.3E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR -0.0526667 9.7E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg22971501 chr19:11199476 LDLR -0.06 9.8E-06
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR -0.0364594 1E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg24113439 chr19:11216129 LDLR 0.003 1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg03637691 chr19:11202610 LDLR -0.04 1E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.042 1E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR 0.054 1E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR 0.036 1E-05
Gadd DA 35945220 STK17B protein levels (SeqId = 5249-31) DNA methylation Whole blood SomaScan protein measurement 774 cg06170501 chr19:11211207 LDLR -0.9 1.1E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg19751789 chr19:11199944 LDLR 0.037 1.1E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR -0.0359779 1.1E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg05249393 chr19:11199883 LDLR -0.0362175 1.1E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0361954 1.2E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg06950392 chr19:11213564 LDLR 0.036 1.2E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg05249393 chr19:11199883 LDLR -0.0357436 1.2E-05
Gadd DA 35945220 CDH15 protein levels (SeqId = 5410-53) DNA methylation Whole blood SomaScan protein measurement 774 cg06170501 chr19:11211207 LDLR -0.9 1.2E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR 0.036 1.2E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR -0.0490573 1.2E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg20196790 chr19:11231222 LDLR 0.21 1.3E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg22006489 chr19:11207145 LDLR 0.046 1.3E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.049 1.3E-05
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR -0.0364577 1.3E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR 0.037 1.4E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg18596381 chr19:11199917 LDLR -0.0358889 1.4E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 3 14671 cg13743731 chr19:11204447 LDLR -0.0353373 1.4E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR -0.0358686 1.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Ischemic Heart Disease Whole blood Basic model 17483 cg19305903 chr19:11203039 LDLR -0.031 1.4E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg26849535 chr19:11199222 LDLR -1.5 1.4E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR -0.0365905 1.4E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg02630186 chr19:11205800 LDLR 0.036 1.4E-05
Ambatipudi S 26864933 DNA methylation Smoking Peripheral blood Current vs never smoking 721 cg07512814 chr19:11203661 LDLR NA 1.4E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0357721 1.5E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg26849535 chr19:11199222 LDLR 0.036 1.5E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg22971501 chr19:11199476 LDLR -0.0086 1.5E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR 0.035 1.5E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 2 14671 cg08483713 chr19:11241669 LDLR 0.041 1.5E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg12013591 chr19:11199965 LDLR -0.168354 1.6E-05
Gadd DA 35945220 RAET1G protein levels (SeqId = 18927-14) DNA methylation Whole blood SomaScan protein measurement 774 cg14331002 chr19:11201349 LDLR 0.71 1.6E-05
Gadd DA 35945220 VAV3 protein levels (SeqId = 9830-109) DNA methylation Whole blood SomaScan protein measurement 774 cg06170501 chr19:11211207 LDLR -0.88 1.6E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Ischemic Heart Disease Whole blood Basic model 17483 cg03637691 chr19:11202610 LDLR -0.025 1.6E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg17992670 chr19:11216306 LDLR 0.036 1.6E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR -0.0357176 1.6E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg22381454 chr19:11199903 LDLR -0.0354334 1.6E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg12013591 chr19:11199965 LDLR -0.168582 1.6E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg22381454 chr19:11199903 LDLR -0.0355429 1.7E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR -0.0360342 1.7E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg02630186 chr19:11205800 LDLR 0.035 1.7E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg22006489 chr19:11207145 LDLR -0.137009 1.7E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR 0.035 1.7E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg12013591 chr19:11199965 LDLR -0.193304 1.8E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg22006489 chr19:11207145 LDLR 0.14 1.8E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg23943360 chr19:11200146 LDLR 0.037 1.8E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR 0.049 1.8E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0380665 1.8E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR 0.036 1.8E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR 0.046 1.8E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR 0.041 1.8E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg22971501 chr19:11199476 LDLR -0.0342133 1.9E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 4 14671 cg18596381 chr19:11199917 LDLR 0.038 1.9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg05249393 chr19:11199883 LDLR -0.06 1.9E-05
Christiansen C 33593402 DNA methylation Smoking Whole blood Current vs never smoking meta-analysis in European samples 912 cg07512814 chr19:11203661 LDLR NA 1.9E-05
Battram T 27886173 DNA methylation Inflammatory bowel disease Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 240 cg19751789 chr19:11199944 LDLR -0.0146 1.9E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR -0.035266 1.9E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.048 1.9E-05
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.038 2E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1V0 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR 0.052 2E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 3 14671 cg18596381 chr19:11199917 LDLR 0.035 2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg12013591 chr19:11199965 LDLR -0.028 2E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR 0.037 2E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR 0.036 2.1E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg18596381 chr19:11199917 LDLR -0.0351135 2.1E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg10640764 chr19:11216364 LDLR 0.0027 2.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Osteoarthritis Whole blood Basic model 16114 cg03637691 chr19:11202610 LDLR -0.044 2.1E-05
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR 0.035 2.1E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR 0.036 2.1E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg06950392 chr19:11213564 LDLR -0.0346641 2.1E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg18596381 chr19:11199917 LDLR -0.0345931 2.1E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.0401429 2.1E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg05249393 chr19:11199883 LDLR -0.0350273 2.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg15373972 chr19:11219638 LDLR 0.081 2.2E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 3 14671 cg06170501 chr19:11211207 LDLR 0.035 2.2E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg03637691 chr19:11202610 LDLR 0.058 2.2E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR -0.0350155 2.2E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg05249393 chr19:11199883 LDLR 0.035 2.3E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR -0.0398658 2.3E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.037 2.3E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR 0.035 2.4E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR 0.037 2.4E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg23943360 chr19:11200146 LDLR 0.036 2.4E-05
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Lifetime consumption discovery 5606 cg03567652 chr19:11242272 LDLR NA 2.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg17992670 chr19:11216306 LDLR 0.098 2.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg26313301 chr19:11219615 LDLR 0.034 2.4E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg22006489 chr19:11207145 LDLR 0.035 2.4E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR 0.035 2.5E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR -0.0349742 2.5E-05
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg07960944 chr19:11199851 LDLR -0.00212 2.5E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg03567652 chr19:11242272 LDLR -0.0347871 2.5E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR -0.0348231 2.5E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR 0.035 2.5E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR -0.0391715 2.6E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR 0.047 2.6E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg07960944 chr19:11199851 LDLR 0.035 2.6E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg18596381 chr19:11199917 LDLR 0.11 2.7E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg19751789 chr19:11199944 LDLR -0.144211 2.7E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.047 2.7E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg22378492 chr19:11202486 LDLR -3.1 2.7E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 2 14671 cg02630186 chr19:11205800 LDLR 0.035 2.7E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Rheumatoid Arthritis (Self-report) Whole blood Basic model 18055 cg03637691 chr19:11202610 LDLR -0.047 2.8E-05
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR -0.0345765 2.8E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR 0.035 2.8E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 3 14671 cg07512814 chr19:11203661 LDLR 0.035 2.8E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg17992670 chr19:11216306 LDLR 0.034 2.8E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR -0.0360181 2.8E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR -0.0369449 2.9E-05
Gadd DA 35945220 ACADL protein levels (SeqId = 17857-6) DNA methylation Whole blood SomaScan protein measurement 774 cg14331002 chr19:11201349 LDLR 0.69 2.9E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR -0.0392696 2.9E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg22006489 chr19:11207145 LDLR 0.035 2.9E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR -0.0469424 2.9E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.034 2.9E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg07512814 chr19:11203661 LDLR -0.0373666 3E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg06950392 chr19:11213564 LDLR 0.033 3E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg08483713 chr19:11241669 LDLR -0.0396916 3E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg22971501 chr19:11199476 LDLR -0.0354007 3E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg07960944 chr19:11199851 LDLR -0.121071 3.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg19751789 chr19:11199944 LDLR -0.026 3.1E-05
Gadd DA 35945220 PAF protein levels (SeqId = 19158-1) DNA methylation Whole blood SomaScan protein measurement 774 cg15373972 chr19:11219638 LDLR -0.81 3.1E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg11556884 chr19:11224442 LDLR 0.13 3.1E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR 0.034 3.1E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR 0.05 3.2E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.034 3.2E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg13743731 chr19:11204447 LDLR 0.22 3.4E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR -0.0350457 3.5E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR -0.0342208 3.5E-05
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg21743867 chr19:11215999 LDLR -0.945784 3.5E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg22971501 chr19:11199476 LDLR 0.036 3.6E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg06950392 chr19:11213564 LDLR 0.034 3.7E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR -0.0501474 3.7E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg05249393 chr19:11199883 LDLR 0.034 3.7E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg02630186 chr19:11205800 LDLR 0.034 3.8E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg26313301 chr19:11219615 LDLR 1.6 3.8E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.0339945 3.8E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg26313301 chr19:11219615 LDLR 0.034 3.8E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR 0.034 3.9E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR -0.0388508 4E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg10640764 chr19:11216364 LDLR 0.0007 4E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg07512814 chr19:11203661 LDLR 0.037 4E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg22378492 chr19:11202486 LDLR -0.0385276 4E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg05249393 chr19:11199883 LDLR 0.034 4E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg06950392 chr19:11213564 LDLR -0.0338505 4.2E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR 0.034 4.2E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR 0.05 4.2E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg03567652 chr19:11242272 LDLR 0.0049 4.2E-05
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR -0.0337941 4.2E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg19751789 chr19:11199944 LDLR 0.034 4.2E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg22971501 chr19:11199476 LDLR 0.034 4.2E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR 0.036 4.3E-05
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 4 14671 cg26849535 chr19:11199222 LDLR -0.0362102 4.3E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR -0.0337615 4.3E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR -0.0354393 4.3E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg11174848 chr19:11200023 LDLR 0.15 4.3E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg22378492 chr19:11202486 LDLR -0.0384415 4.3E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg03567652 chr19:11242272 LDLR -0.0377916 4.4E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg26313301 chr19:11219615 LDLR 0.035 4.4E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 2 14671 cg19305903 chr19:11203039 LDLR 0.038 4.4E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg07960944 chr19:11199851 LDLR 0.034 4.5E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg20196790 chr19:11231222 LDLR -0.245075 4.6E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg23943360 chr19:11200146 LDLR 0.035 4.6E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR -0.033632 4.6E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR 0.034 4.6E-05
Gadd DA 35945220 TNFSF4 protein levels (SeqId = 2839-2) DNA methylation Whole blood SomaScan protein measurement 774 cg14331002 chr19:11201349 LDLR 0.67 4.7E-05
Gadd DA 35945220 CCL16 protein levels (SeqId = 4913-78) DNA methylation Whole blood SomaScan protein measurement 774 cg22381454 chr19:11199903 LDLR -0.72 4.7E-05
Battram T 23334450 DNA methylation Rheumatoid arthritis Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE42861 689 cg27477601 chr19:11216203 LDLR -0.0061 4.7E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Chronic Kidney Disease Whole blood Basic model 18000 cg19305903 chr19:11203039 LDLR -0.016 4.7E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg03637691 chr19:11202610 LDLR -0.133856 4.7E-05
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 2 14671 cg26313301 chr19:11219615 LDLR -0.0352864 4.7E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 3 14671 cg07960944 chr19:11199851 LDLR -0.0334873 4.8E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg22971501 chr19:11199476 LDLR -0.053 4.8E-05
Gadd DA 35945220 VOPP1 protein levels (SeqId = 14618-26) DNA methylation Whole blood SomaScan protein measurement 774 cg15373972 chr19:11219638 LDLR -0.79 4.8E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg13351962 chr19:11200983 LDLR 0.034 4.8E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg17992670 chr19:11216306 LDLR 0.033 4.9E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg07512814 chr19:11203661 LDLR 0.036 4.9E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg24113439 chr19:11216129 LDLR -0.00642 4.9E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 4 14671 cg26313301 chr19:11219615 LDLR 0.037 4.9E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg22381454 chr19:11199903 LDLR -0.0336208 5E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg02630186 chr19:11205800 LDLR 0.033 5E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg02630186 chr19:11205800 LDLR 0.033 5E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg17992670 chr19:11216306 LDLR -0.190495 5E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg12013591 chr19:11199965 LDLR 0.035 5E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg26313301 chr19:11219615 LDLR 0.0022 5.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Osteoarthritis (Self-report) Whole blood Basic model 18060 cg03637691 chr19:11202610 LDLR -0.077 5.1E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg26849535 chr19:11199222 LDLR 0.034 5.1E-05
Josephine Robertson 41361833 DNA methylation Q14520 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.0334161 5.2E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg06950392 chr19:11213564 LDLR -0.0340346 5.2E-05
Gadd DA 35945220 C4orf32 protein levels (SeqId = 9490-3) DNA methylation Whole blood SomaScan protein measurement 774 cg14331002 chr19:11201349 LDLR 0.67 5.2E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg03637691 chr19:11202610 LDLR -0.133481 5.3E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR -0.0449463 5.3E-05
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 4 14671 cg07512814 chr19:11203661 LDLR 0.041 5.3E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR 0.038 5.3E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg12013591 chr19:11199965 LDLR 0.034 5.4E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg13351962 chr19:11200983 LDLR 0.034 5.5E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg02630186 chr19:11205800 LDLR -0.0333371 5.5E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg03567652 chr19:11242272 LDLR 0.036 5.5E-05
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg07512814 chr19:11203661 LDLR NA 5.5E-05
Gadd DA 35945220 TREML2 protein levels (SeqId = 5736-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06170501 chr19:11211207 LDLR -0.82 5.5E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg06950392 chr19:11213564 LDLR 0.034 5.5E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg23943360 chr19:11200146 LDLR 0.034 5.5E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg06950392 chr19:11213564 LDLR -0.0332402 5.7E-05
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 3 14671 cg03637691 chr19:11202610 LDLR -0.0455352 5.7E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg21743867 chr19:11215999 LDLR -0.241609 5.7E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg07960944 chr19:11199851 LDLR -0.0331435 5.9E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg02630186 chr19:11205800 LDLR -0.0331313 6E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg22378492 chr19:11202486 LDLR -0.0331241 6E-05
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous decade consumption discovery 5606 cg03567652 chr19:11242272 LDLR NA 6E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR -0.0331189 6E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg22381454 chr19:11199903 LDLR -0.032642 6E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR 0.037 6E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Osteoarthritis (Self-report) Whole blood Fully-adjusted model 14391 cg17992670 chr19:11216306 LDLR 0.14 6.1E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR -0.0330638 6.2E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR -0.0341561 6.2E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR -0.0330431 6.3E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 3 14671 cg12013591 chr19:11199965 LDLR 0.034 6.3E-05
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR -0.0330361 6.3E-05
Gadd DA 35945220 UBE2G2 protein levels (SeqId = 9199-6) DNA methylation Whole blood SomaScan protein measurement 774 cg06170501 chr19:11211207 LDLR -0.81 6.3E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg22971501 chr19:11199476 LDLR 0.034 6.3E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR -0.0330001 6.4E-05
Gadd DA 35945220 HEXB protein levels (SeqId = 15470-11) DNA methylation Whole blood SomaScan protein measurement 774 cg19751789 chr19:11199944 LDLR -0.68 6.4E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg22378492 chr19:11202486 LDLR -0.0376618 6.4E-05
Darina Czamara 38600394 DNA methylation sex placenta meta-analysis of robust linear regression results per cohort 746 cg07960944 chr19:11199851 LDLR -0.1406204 6.5E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg03554660 chr19:11214666 LDLR 0.0095 6.5E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg26849535 chr19:11199222 LDLR -0.0335119 6.5E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0329442 6.6E-05
Gadd DA 35945220 COPE protein levels (SeqId = 19310-81) DNA methylation Whole blood SomaScan protein measurement 774 cg14331002 chr19:11201349 LDLR 0.66 6.6E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 3 14671 cg13404814 chr19:11198964 LDLR -0.0323086 6.7E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg03567652 chr19:11242272 LDLR -0.0336579 6.9E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg26313301 chr19:11219615 LDLR -0.0333708 6.9E-05
Gadd DA 35945220 GKN2 protein levels (SeqId = 6416-8) DNA methylation Whole blood SomaScan protein measurement 774 cg19751789 chr19:11199944 LDLR -0.671 7E-05
Gross AM 27105112 DNA methylation HIV infection Neutrophils Neutrophils 60 cg24113439 chr19:11216129 LDLR -0.072539 7.1E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 4 14671 cg15373972 chr19:11219638 LDLR 0.038 7.1E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg22381454 chr19:11199903 LDLR 0.033 7.2E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg07960944 chr19:11199851 LDLR -0.0320603 7.3E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg22971501 chr19:11199476 LDLR -0.0338721 7.3E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg06950392 chr19:11213564 LDLR -0.0327203 7.4E-05
Gadd DA 35945220 GZMA protein levels (SeqId = 3440-7) DNA methylation Whole blood SomaScan protein measurement 774 cg12013591 chr19:11199965 LDLR -0.81 7.4E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg22971501 chr19:11199476 LDLR -0.0328794 7.5E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg18596381 chr19:11199917 LDLR 0.032 7.6E-05
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 2 14671 cg19751789 chr19:11199944 LDLR -0.0330294 7.7E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg05249393 chr19:11199883 LDLR 0.033 7.7E-05
Gadd DA 35945220 PPP3R2 protein levels (SeqId = 18866-8) DNA methylation Whole blood SomaScan protein measurement 774 cg14331002 chr19:11201349 LDLR 0.65 7.8E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg17992670 chr19:11216306 LDLR 0.00064 7.8E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg06950392 chr19:11213564 LDLR -0.0319824 7.8E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg17992670 chr19:11216306 LDLR 0.033 7.9E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg19305903 chr19:11203039 LDLR 0.037 8E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg05249393 chr19:11199883 LDLR 0.032 8.1E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.033 8.1E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg07512814 chr19:11203661 LDLR 0.035 8.2E-05
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg19305903 chr19:11203039 LDLR -0.0325106 8.2E-05
Chatziioannou A 28225026 DNA methylation Current vs never smoking Whole blood - 454 cg07512814 chr19:11203661 LDLR NA 8.2E-05
Gadd DA 35945220 PCDHB1 protein levels (SeqId = 9941-70) DNA methylation Whole blood SomaScan protein measurement 774 cg14331002 chr19:11201349 LDLR 0.65 8.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Ischemic Heart Disease Whole blood Basic model 17483 cg26313301 chr19:11219615 LDLR 0.03 8.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Kidney Disease (Estimated) Whole blood Fully-adjusted Model 14315 cg03637691 chr19:11202610 LDLR -0.041 8.2E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg22378492 chr19:11202486 LDLR -0.0367549 8.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Liver Cirrhosis Whole blood Basic model 18325 cg12876142 chr19:11227689 LDLR 0.013 8.4E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 1 14671 cg07512814 chr19:11203661 LDLR 0.032 8.6E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg12013591 chr19:11199965 LDLR 0.032 8.7E-05
Gadd DA 35945220 HNF4A protein levels (SeqId = 10041-3) DNA methylation Whole blood SomaScan protein measurement 774 cg06170501 chr19:11211207 LDLR -0.8 8.7E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg08483713 chr19:11241669 LDLR 0.032 8.8E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg06950392 chr19:11213564 LDLR 0.18 8.9E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR 0.032 8.9E-05
Gadd DA 35945220 SVIP protein levels (SeqId = 18285-6) DNA methylation Whole blood SomaScan protein measurement 774 cg14331002 chr19:11201349 LDLR 0.65 8.9E-05
Gadd DA 35945220 PBK protein levels (SeqId = 17475-18) DNA methylation Whole blood SomaScan protein measurement 774 cg14331002 chr19:11201349 LDLR 0.65 8.9E-05
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg07960944 chr19:11199851 LDLR NA 9E-05
Darina Czamara 38600394 DNA methylation sex placenta meta-analysis of robust linear regression results per cohort 746 cg22808547 chr19:11236962 LDLR 0.13 9E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg15373972 chr19:11219638 LDLR 0.034 9E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR 0.033 9E-05
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg03567652 chr19:11242272 LDLR 0.032 9.1E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 3 14671 cg17992670 chr19:11216306 LDLR 0.03 9.1E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg12013591 chr19:11199965 LDLR 0.033 9.2E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg05249393 chr19:11199883 LDLR 0.12 9.2E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg22378492 chr19:11202486 LDLR -0.128796 9.2E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg12013591 chr19:11199965 LDLR -0.0333206 9.2E-05
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 4 14671 cg19305903 chr19:11203039 LDLR 0.048 9.2E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg17992670 chr19:11216306 LDLR 0.032 9.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg12013591 chr19:11199965 LDLR -0.073 9.4E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR -0.0322352 9.4E-05
Gadd DA 35945220 IFNA5 protein levels (SeqId = 6210-100) DNA methylation Whole blood SomaScan protein measurement 774 cg14331002 chr19:11201349 LDLR 0.64 9.5E-05
Gadd DA 35945220 HMGCS1 protein levels (SeqId = 13496-19) DNA methylation Whole blood SomaScan protein measurement 774 cg26313301 chr19:11219615 LDLR 0.77 9.5E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR 0.034 9.6E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg03637691 chr19:11202610 LDLR 0.044 9.6E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 1 14671 cg15373972 chr19:11219638 LDLR -0.0321992 9.6E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg03567652 chr19:11242272 LDLR -0.0321907 9.6E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg22378492 chr19:11202486 LDLR -0.0371894 9.6E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg22381454 chr19:11199903 LDLR 0.031 9.7E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg03567652 chr19:11242272 LDLR 0.032 9.9E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg03637691 chr19:11202610 LDLR 0.032 9.9E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 4 14671 cg19751789 chr19:11199944 LDLR -0.0340831 9.9E-05
Hoang 34516295 DNA methylation atrazine whole blood discovery 363 cg13404814 chr19:11198964 LDLR -0.01239 9.9E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg15373972 chr19:11219638 LDLR 0.034 9.9E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 2 14671 cg06170501 chr19:11211207 LDLR 0.032 1E-04

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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