Search results for MC2R
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg00335286 | chr18:13916355 | MC2R | -0.0024 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg03664443 | chr18:13916330 | MC2R | -0.0039 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg05667256 | chr18:13915583 | MC2R | -0.0021 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg20494779 | chr18:13916113 | MC2R | -0.0017 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg25924472 | chr18:13884152 | MC2R | -0.0009 | 0E+00 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg20494779 | chr18:13916113 | MC2R | 0.54 | 2.4E-135 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg00335286 | chr18:13916355 | MC2R | 0.43 | 1.6E-122 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg03664443 | chr18:13916330 | MC2R | 0.3 | 5.4E-110 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg24922596 | chr18:13915573 | MC2R | 0.0013 | 1.5E-29 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg03664443 | chr18:13916330 | MC2R | 0.0027 | 6.1E-20 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg00335286 | chr18:13916355 | MC2R | -0.48691 | 3.7E-18 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg20494779 | chr18:13916113 | MC2R | -0.44186 | 1.3E-17 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg03664443 | chr18:13916330 | MC2R | -0.35828 | 1.8E-16 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg11564670 | chr18:13915006 | MC2R | -0.03451 | 4E-16 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg20494779 | chr18:13916113 | MC2R | 0.00091 | 6.7E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg24922596 | chr18:13915573 | MC2R | -0.001 | 2.4E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg17828058 | chr18:13909311 | MC2R | 0.06 | 4.5E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg05667256 | chr18:13915583 | MC2R | 0.0018 | 6.7E-13 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg11564670 | chr18:13915006 | MC2R | -0.16898 | 5E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg20494779 | chr18:13916113 | MC2R | 0.054 | 4.6E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg17828058 | chr18:13909311 | MC2R | 0.053 | 1.6E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg03664443 | chr18:13916330 | MC2R | -0.01 | 2.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg00527908 | chr18:13893625 | MC2R | 0.052 | 2.8E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg24922596 | chr18:13915573 | MC2R | 0.0038 | 2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04228045 | chr18:13889915 | MC2R | 0.048 | 4.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg08578419 | chr18:13886969 | MC2R | 0.048 | 5.3E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg25924472 | chr18:13884152 | MC2R | 0.00066 | 7.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg14829190 | chr18:13893806 | MC2R | 0.046 | 2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04228045 | chr18:13889915 | MC2R | 0.045 | 3.6E-08 |
| Li M | 33279932 | DNA methylation | Schizophrenia | Whole blood | main | 999 | cg24922596 | chr18:13915573 | MC2R | -0.01001 | 5.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg00527908 | chr18:13893625 | MC2R | 0.044 | 9.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg14829190 | chr18:13893806 | MC2R | -0.0436029 | 1.3E-07 |
| Li M | 33279932 | DNA methylation | Schizophrenia | Whole blood | adjusted for cell composition | 999 | cg24922596 | chr18:13915573 | MC2R | NA | 2.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg00527908 | chr18:13893625 | MC2R | 0.042 | 2.8E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg17828058 | chr18:13909311 | MC2R | -0.193793 | 3.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg00527908 | chr18:13893625 | MC2R | 0.04 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg04228045 | chr18:13889915 | MC2R | 0.04 | 1.1E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg26344168 | chr18:13884969 | MC2R | -0.00049 | 1.2E-06 |
| Kazmi N | 31230546 | DNA methylation | Hypertensive disorders of pregnancy | Cord blood | Meta analysis adjusted model | 5242 | cg05667256 | chr18:13915583 | MC2R | 0.0054 | 1.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg20494779 | chr18:13916113 | MC2R | 0.04 | 1.4E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Liver Cirrhosis | Whole blood | Fully-adjusted model | 14358 | cg04228045 | chr18:13889915 | MC2R | -0.011 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg20494779 | chr18:13916113 | MC2R | 0.039 | 2.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg14829190 | chr18:13893806 | MC2R | -0.0402184 | 3.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg17828058 | chr18:13909311 | MC2R | -0.0382071 | 3.7E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg03664443 | chr18:13916330 | MC2R | 0.0069 | 5.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 3 | 14671 | cg14829190 | chr18:13893806 | MC2R | -0.0384902 | 8.7E-06 |
| Gadd DA | 35945220 | AHSG protein levels (SeqId = 3581-53) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg17444561 | chr18:13915600 | MC2R | -0.66 | 9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg00527908 | chr18:13893625 | MC2R | -0.036564 | 9.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg17828058 | chr18:13909311 | MC2R | -0.0392384 | 9.7E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg17828058 | chr18:13909311 | MC2R | -0.167452 | 1E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg04228045 | chr18:13889915 | MC2R | 0.14 | 1.2E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg05667256 | chr18:13915583 | MC2R | 0.0054 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg00527908 | chr18:13893625 | MC2R | 0.036 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg17828058 | chr18:13909311 | MC2R | -0.0357868 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 3 | 14671 | cg14829190 | chr18:13893806 | MC2R | -0.0373949 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00527908 | chr18:13893625 | MC2R | 0.036 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 2 | 14671 | cg14829190 | chr18:13893806 | MC2R | -0.0374198 | 1.7E-05 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg22364075 | chr18:13916462 | MC2R | -0.1377605 | 2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg20494779 | chr18:13916113 | MC2R | -0.195688 | 2.2E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg20494779 | chr18:13916113 | MC2R | 0.0026 | 2.8E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Liver Cirrhosis | Whole blood | Basic model | 18325 | cg04228045 | chr18:13889915 | MC2R | -0.0094 | 2.9E-05 |
| Anna Ulrich | 38184627 | DNA methylation | Idiopathic/heritable pulmonary arterial hypertension | whole blood | Discovery | 1655 | cg22624572 | chr18:13886087 | MC2R | -18.0 | 3.1E-05 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg05779523 | chr18:13914358 | MC2R | -0.02385 | 4.8E-05 |
| Lunnon K | 25129077 | DNA methylation | Alzheimers disease Braak stage | Whole blood | Discovery in blood | 57 | cg05667256 | chr18:13915583 | MC2R | NA | 6.5E-05 |
| Gadd DA | 35945220 | KCNE5 protein levels (SeqId = 8908-14) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg11564670 | chr18:13915006 | MC2R | -0.47 | 7.3E-05 |
| Gadd DA | 35945220 | ITCH protein levels (SeqId = 12551-3) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg17828058 | chr18:13909311 | MC2R | 0.7 | 8.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg14829190 | chr18:13893806 | MC2R | 0.033 | 8.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 2 | 14671 | cg00527908 | chr18:13893625 | MC2R | 0.034 | 9.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg08578419 | chr18:13886969 | MC2R | 0.033 | 9.8E-05 |
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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.
