Search results for MDC1
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg00575529 | chr6:30685080 | MDC1 | 0.00048 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg05300316 | chr6:30685246 | MDC1 | 0.0004 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg05546064 | chr6:30685074 | MDC1 | 0.00041 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg06315208 | chr6:30684406 | MDC1 | -0.0031 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg07257768 | chr6:30684736 | MDC1 | -0.0039 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg10277195 | chr6:30684931 | MDC1 | 0.00082 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg11498582 | chr6:30684340 | MDC1 | -0.0022 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg12814525 | chr6:30685250 | MDC1 | 0.00048 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg16580700 | chr6:30685744 | MDC1 | -0.0015 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg17188180 | chr6:30684840 | MDC1 | -0.00012 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg17302862 | chr6:30685540 | MDC1 | -0.00048 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg21105955 | chr6:30684478 | MDC1 | -0.004 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg24700494 | chr6:30684284 | MDC1 | 0.016 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg27369934 | chr6:30684905 | MDC1 | -0.00021 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg26454601 | chr6:30683823 | MDC1 | 0.0015 | 1.7E-116 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg11498582 | chr6:30684340 | MDC1 | 0.39 | 6.1E-115 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg07257768 | chr6:30684736 | MDC1 | 0.23 | 2.1E-112 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg24700494 | chr6:30684284 | MDC1 | 0.31 | 3.8E-106 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg03844211 | chr6:30684773 | MDC1 | 0.091 | 1.7E-105 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.177795 | 1.8E-104 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg22724063 | chr6:30684760 | MDC1 | 0.097 | 5.9E-104 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg21105955 | chr6:30684478 | MDC1 | 0.27 | 1.4E-101 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg01533397 | chr6:30684278 | MDC1 | 0.25 | 4.2E-90 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg09232906 | chr6:30684280 | MDC1 | 0.16 | 3.7E-82 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.14853 | 3.9E-73 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.133013 | 6.8E-59 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg06315208 | chr6:30684406 | MDC1 | 0.0022 | 1.1E-52 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.12 | 1.6E-49 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg16580700 | chr6:30685744 | MDC1 | 0.16 | 1.2E-48 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg10511301 | chr6:30683561 | MDC1 | 0.041 | 1.2E-45 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg25988105 | chr6:30681476 | MDC1 | 0.0024 | 3.1E-45 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg07257768 | chr6:30684736 | MDC1 | NA | 7.4E-42 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.107863 | 3.2E-39 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg10925640 | chr6:30684572 | MDC1 | 0.11 | 4.4E-37 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.100544 | 2.8E-34 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg26454601 | chr6:30683823 | MDC1 | 0.0045 | 1.3E-32 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg10423170 | chr6:30681943 | MDC1 | 0.031 | 1.7E-32 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.097 | 7E-32 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg03151709 | chr6:30686511 | MDC1 | 0.065 | 4.3E-31 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg01533397 | chr6:30684278 | MDC1 | NA | 1.3E-29 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.092638 | 2.5E-29 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg21643358 | chr6:30681110 | MDC1 | 0.043 | 1.7E-27 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.089 | 2.7E-27 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg11498582 | chr6:30684340 | MDC1 | 0.0011 | 1.1E-26 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.088 | 1.2E-26 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | -0.0870975 | 4.2E-26 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0854755 | 3.4E-25 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg11498582 | chr6:30684340 | MDC1 | NA | 1.1E-24 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg11281993 | chr6:30682871 | MDC1 | 0.0011 | 4.2E-24 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg21105955 | chr6:30684478 | MDC1 | 0.0026 | 8.2E-24 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg24700494 | chr6:30684284 | MDC1 | NA | 1.7E-23 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg07129907 | chr6:30683787 | MDC1 | 0.0008 | 5.5E-23 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0787875 | 1.2E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.078 | 1.9E-21 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 2901913 (gene symbol: TUBB) | Whole blood | Meta-analysis | 4170 | cg16580700 | chr6:30685744 | MDC1 | NA | 2.6E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.077 | 6.6E-21 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0998061 | 1.1E-20 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | ch.6.738234R | chr6:30679284 | MDC1 | 0.01 | 3E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | -0.0756741 | 4.4E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | -0.0750359 | 9E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0731637 | 7.1E-19 |
| Marttila S | 25888029 | DNA methylation | Age group | Peripheral blood mononuclear cells | - | 143 | cg07257768 | chr6:30684736 | MDC1 | -0.8012948 | 2.3E-18 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg07257768 | chr6:30684736 | MDC1 | -0.0082 | 2.4E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0717381 | 3.3E-18 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg18512512 | chr6:30685686 | MDC1 | 0.042 | 7.2E-18 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg03563090 | chr6:30684878 | MDC1 | 0.012 | 8.2E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.067 | 3.8E-16 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg03844211 | chr6:30684773 | MDC1 | NA | 4.2E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0653692 | 2.3E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.065 | 2.3E-15 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg07257768 | chr6:30684736 | MDC1 | -0.038 | 3.1E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg24700494 | chr6:30684284 | MDC1 | -0.0019 | 3.1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.065 | 3.3E-15 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg07229198 | chr6:30685635 | MDC1 | 0.038 | 3.9E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg18301048 | chr6:30685243 | MDC1 | 0.00019 | 4.2E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.064 | 7.1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0832352 | 1E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.064 | 1E-14 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg23590244 | chr6:30685311 | MDC1 | -9.7e-05 | 1.2E-14 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg15622885 | chr6:30685406 | MDC1 | -9.4e-05 | 1.7E-14 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg07257768 | chr6:30684736 | MDC1 | -0.212223 | 4.7E-14 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.081 | 5E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0620085 | 5.6E-14 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg07257768 | chr6:30684736 | MDC1 | -0.211237 | 6.9E-14 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0615207 | 8.8E-14 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg11281993 | chr6:30682871 | MDC1 | 0.016 | 8.8E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0612922 | 1.1E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.061 | 1.6E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0599848 | 3.6E-13 |
| Joehanes R | 27651444 | DNA methylation | Current versus never smoking | Whole blood, CD4+ T cells or monocytes | Current vs never smoking | 9389 | cg07257768 | chr6:30684736 | MDC1 | -0.0089 | 4.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.059 | 6.5E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.059 | 1.1E-12 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg03157605 | chr6:30685409 | MDC1 | 0.00036 | 1.1E-12 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg24134020 | chr6:30681924 | MDC1 | 0.011 | 2.1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0578399 | 2.4E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.064 | 3.5E-12 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg07656347 | chr6:30684837 | MDC1 | 0.00039 | 3.5E-12 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg11498582 | chr6:30684340 | MDC1 | -0.00534 | 3.7E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.124619 | 5.2E-12 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg00682802 | chr6:30682855 | MDC1 | -0.01335 | 9.1E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg03844211 | chr6:30684773 | MDC1 | -0.212327 | 9.2E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | 0.056 | 1.4E-11 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg03151709 | chr6:30686511 | MDC1 | -0.02815 | 1.5E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.122041 | 1.5E-11 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg06315208 | chr6:30684406 | MDC1 | -0.041 | 1.6E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.071184 | 1.8E-11 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0549783 | 2.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0548572 | 3E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.055 | 3E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg10277195 | chr6:30684931 | MDC1 | 0.00077 | 3.6E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg06315208 | chr6:30684406 | MDC1 | -0.233845 | 3.9E-11 |
| Marttila S | 25888029 | DNA methylation | Age group | Peripheral blood mononuclear cells | - | 143 | cg03151709 | chr6:30686511 | MDC1 | -0.73255804 | 4.2E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.054 | 5.5E-11 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 2948564 (gene symbol: MDC1) | Whole blood | Meta-analysis | 4170 | cg26193015 | chr6:30683144 | MDC1 | NA | 5.8E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg15024975 | chr6:30685170 | MDC1 | 0.00039 | 6.4E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg03844211 | chr6:30684773 | MDC1 | -0.202387 | 7.3E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | -0.0537408 | 7.3E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg24700494 | chr6:30684284 | MDC1 | 0.0019 | 8.1E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg06315208 | chr6:30684406 | MDC1 | -0.228698 | 9.9E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg18512512 | chr6:30685686 | MDC1 | -0.0011 | 1E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg21643358 | chr6:30681110 | MDC1 | 0.0013 | 1.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.114907 | 1.4E-10 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg06315208 | chr6:30684406 | MDC1 | -0.00466 | 1.7E-10 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg19483962 | chr6:30681100 | MDC1 | -2.308801 | 1.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.058 | 3E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg03151709 | chr6:30686511 | MDC1 | -0.0015 | 3.5E-10 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg09232906 | chr6:30684280 | MDC1 | -1.843435 | 3.7E-10 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg11968414 | chr6:30684868 | MDC1 | 0.017 | 4.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.067 | 4.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.113748 | 4.5E-10 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg18512512 | chr6:30685686 | MDC1 | 0.03 | 4.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0511611 | 5.6E-10 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg13983052 | chr6:30685120 | MDC1 | 0.008 | 6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | 0.051 | 6.7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.051 | 6.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.051 | 7E-10 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg21643358 | chr6:30681110 | MDC1 | -2.247348 | 7.2E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg25988105 | chr6:30681476 | MDC1 | -0.0012 | 7.4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.066 | 9.7E-10 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg03844211 | chr6:30684773 | MDC1 | -0.00373 | 1.6E-09 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg07229198 | chr6:30685635 | MDC1 | 0.011 | 1.6E-09 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg07257768 | chr6:30684736 | MDC1 | -1.7 | 1.7E-09 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg19483962 | chr6:30681100 | MDC1 | 0.017 | 1.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | -0.0493762 | 2.2E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg06315208 | chr6:30684406 | MDC1 | 0.0055 | 2.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.063 | 3.1E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg10925640 | chr6:30684572 | MDC1 | -0.0016 | 3.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.105991 | 4.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0539244 | 4.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | 0.048 | 4.6E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg24134020 | chr6:30681924 | MDC1 | 0.00041 | 4.6E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg16253551 | chr6:30685136 | MDC1 | 0.16 | 4.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.062 | 5.4E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg07257768 | chr6:30684736 | MDC1 | 0.011 | 5.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.048 | 5.7E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg07257768 | chr6:30684736 | MDC1 | -0.163691 | 5.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.048 | 6.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | -0.0475141 | 8.5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.053 | 8.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.061 | 9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.047 | 9.3E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg16253551 | chr6:30685136 | MDC1 | 0.00042 | 1E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg13983052 | chr6:30685120 | MDC1 | 0.0079 | 1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0470787 | 1.2E-08 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg20835659 | chr6:30681672 | MDC1 | 0.033 | 1.2E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg21105955 | chr6:30684478 | MDC1 | 0.0095 | 1.4E-08 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg04181831 | chr6:30684873 | MDC1 | -1.452609 | 1.5E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg26568546 | chr6:30682678 | MDC1 | -0.01349 | 1.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.052 | 1.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0465849 | 1.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0470525 | 1.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0594659 | 1.9E-08 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg26454601 | chr6:30683823 | MDC1 | -0.00851 | 2E-08 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg03844211 | chr6:30684773 | MDC1 | -3.3 | 2.5E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg13983052 | chr6:30685120 | MDC1 | 0.00023 | 2.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | 0.046 | 2.6E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg24700494 | chr6:30684284 | MDC1 | 0.024 | 2.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 3 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.051 | 2.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.101795 | 2.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.046 | 3E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg00682802 | chr6:30682855 | MDC1 | 0.00056 | 3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | -0.0455436 | 3.4E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg07129907 | chr6:30683787 | MDC1 | 0.0024 | 3.9E-08 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg03151709 | chr6:30686511 | MDC1 | -0.03 | 4.6E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg04381681 | chr6:30681593 | MDC1 | -0.00088 | 4.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0450595 | 4.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | 0.046 | 4.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0450024 | 4.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0448582 | 5.5E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg26552907 | chr6:30667625 | MDC1 | -0.03615 | 5.6E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg16253551 | chr6:30685136 | MDC1 | 0.0026 | 5.7E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg10277195 | chr6:30684931 | MDC1 | 0.0023 | 6.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0445729 | 6.6E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg11968414 | chr6:30684868 | MDC1 | 0.00046 | 6.9E-08 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg12814525 | chr6:30685250 | MDC1 | NA | 8.5E-08 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg07656347 | chr6:30684837 | MDC1 | 0.0088 | 8.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 1 | 14671 | cg07257768 | chr6:30684736 | MDC1 | 0.044 | 1E-07 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg24134020 | chr6:30681924 | MDC1 | -0.01114 | 1.1E-07 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg01533397 | chr6:30684278 | MDC1 | NA | 1.1E-07 |
| Joehanes R | 27651444 | DNA methylation | Current versus never smoking | Whole blood, CD4+ T cells or monocytes | Current vs never smoking | 9389 | cg11498582 | chr6:30684340 | MDC1 | -0.0053 | 1.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 3 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.048 | 1.2E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg22596454 | chr6:30685146 | MDC1 | 0.00032 | 1.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0434132 | 1.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.043 | 1.4E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg06315208 | chr6:30684406 | MDC1 | 0.0064 | 1.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.054 | 2E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg22596454 | chr6:30685146 | MDC1 | 0.15 | 2.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 3 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.047834 | 2.1E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg10816127 | chr6:30685626 | MDC1 | -0.00036 | 2.1E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg12814525 | chr6:30685250 | MDC1 | 0.0019 | 2.3E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg22782446 | chr6:30685087 | MDC1 | 0.00021 | 2.4E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg07257768 | chr6:30684736 | MDC1 | -0.178654 | 2.4E-07 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg11498582 | chr6:30684340 | MDC1 | -0.038 | 2.7E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg07229198 | chr6:30685635 | MDC1 | -0.00026 | 2.9E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg03844211 | chr6:30684773 | MDC1 | -0.159295 | 2.9E-07 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg05317081 | chr6:30685534 | MDC1 | -1.258727 | 3.2E-07 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg24700494 | chr6:30684284 | MDC1 | -1.154209 | 3.3E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg09232906 | chr6:30684280 | MDC1 | -0.00078 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.042 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | 0.042 | 3.5E-07 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg01533397 | chr6:30684278 | MDC1 | -1.315529 | 3.8E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg03844211 | chr6:30684773 | MDC1 | -0.173408 | 4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0417298 | 4.3E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg00575529 | chr6:30685080 | MDC1 | 0.0018 | 4.8E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg10511301 | chr6:30683561 | MDC1 | 0.0014 | 5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0534072 | 5.9E-07 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Previous week consumption discovery | 5606 | cg11498582 | chr6:30684340 | MDC1 | NA | 7.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.041 | 7.7E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg05546064 | chr6:30685074 | MDC1 | 0.0014 | 7.8E-07 |
| Gadd DA | 35945220 | TTC9B protein levels (SeqId = 9386-42) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.82 | 8.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P15169 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.053 | 8.6E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg11498582 | chr6:30684340 | MDC1 | 0.0038 | 8.8E-07 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg03844211 | chr6:30684773 | MDC1 | -0.026 | 8.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg03844211 | chr6:30684773 | MDC1 | 0.041 | 9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0449324 | 9.7E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg11281993 | chr6:30682871 | MDC1 | 0.003 | 9.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg03151709 | chr6:30686511 | MDC1 | 0.04 | 9.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.051 | 9.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.04 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 2 | 14671 | cg03844211 | chr6:30684773 | MDC1 | -0.0402884 | 1.2E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg22724063 | chr6:30684760 | MDC1 | -0.13004 | 1.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0403685 | 1.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg03844211 | chr6:30684773 | MDC1 | -0.0399005 | 1.3E-06 |
| Gadd DA | 35945220 | DRAXIN protein levels (SeqId = 7084-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.8 | 1.4E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg22596454 | chr6:30685146 | MDC1 | 0.002 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0398521 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 3 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0440743 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.039 | 1.8E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg03844211 | chr6:30684773 | MDC1 | 0.0024 | 1.8E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg26193015 | chr6:30683144 | MDC1 | 0.0011 | 1.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg03151709 | chr6:30686511 | MDC1 | -0.0392604 | 2E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg05546064 | chr6:30685074 | MDC1 | 0.0056 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg07257768 | chr6:30684736 | MDC1 | 0.039 | 2.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 4 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.12 | 2.2E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg22724063 | chr6:30684760 | MDC1 | 0.0022 | 2.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.039 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.038879 | 2.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg10925640 | chr6:30684572 | MDC1 | 0.039 | 2.6E-06 |
| Gadd DA | 35945220 | PRRG1 protein levels (SeqId = 9008-6) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.785 | 2.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0387736 | 2.6E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg11281993 | chr6:30682871 | MDC1 | -0.00054 | 2.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.04294 | 3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0498881 | 3.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q9Y5Y7 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.038 | 3.1E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg22724063 | chr6:30684760 | MDC1 | -0.124712 | 3.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.038 | 3.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0426881 | 3.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P15169 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.038 | 3.3E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg05300316 | chr6:30685246 | MDC1 | 0.0014 | 3.4E-06 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg03157605 | chr6:30685409 | MDC1 | -1.358443 | 3.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0499938 | 3.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0386069 | 3.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.045 | 3.7E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Liver Cirrhosis | Whole blood | Basic model | 18325 | cg11498582 | chr6:30684340 | MDC1 | -0.013 | 3.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg03151709 | chr6:30686511 | MDC1 | 0.038 | 3.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0381 | 3.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg03151709 | chr6:30686511 | MDC1 | -0.0406396 | 4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.042 | 4.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.038 | 4.3E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg11498582 | chr6:30684340 | MDC1 | -0.194689 | 4.3E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg09859103 | chr6:30685402 | MDC1 | 0.0067 | 4.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg03151709 | chr6:30686511 | MDC1 | 0.038 | 4.5E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg09232906 | chr6:30684280 | MDC1 | 0.005 | 4.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.038 | 4.6E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg26552907 | chr6:30667625 | MDC1 | 0.016 | 4.8E-06 |
| Singmann P | 26500701 | DNA methylation | Sex | Whole blood | KORA F4 | 1799 | cg11498582 | chr6:30684340 | MDC1 | NA | 4.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.037759 | 5.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | 0.038 | 5.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02760 | whole blood | OSCA model 2 | 14671 | cg03844211 | chr6:30684773 | MDC1 | 0.038 | 5.2E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg03151709 | chr6:30686511 | MDC1 | -0.145819 | 5.2E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg03563090 | chr6:30684878 | MDC1 | 0.0013 | 5.2E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg00682802 | chr6:30682855 | MDC1 | -0.00038 | 5.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0373748 | 5.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg23886643 | chr6:30670957 | MDC1 | -0.0373316 | 6.1E-06 |
| Gadd DA | 35945220 | CRIM1 protein levels (SeqId = 8699-43) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.75 | 6.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 2 | 14671 | cg03844211 | chr6:30684773 | MDC1 | -0.037404 | 6.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P36955 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.048 | 6.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0369736 | 7.5E-06 |
| Gadd DA | 35945220 | MRAS protein levels (SeqId = 18297-8) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.75 | 7.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.048 | 7.6E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg23485400 | chr6:30685229 | MDC1 | 0.00037 | 7.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0369151 | 7.7E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg26454601 | chr6:30683823 | MDC1 | -0.142734 | 7.8E-06 |
| Gadd DA | 35945220 | NEURL4 protein levels (SeqId = 13468-5) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.74 | 8.1E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg06074256 | chr6:30684939 | MDC1 | -7.3e-05 | 8.5E-06 |
| Hannon E | 27572077 | DNA methylation | Schizophrenia | Whole blood | Phase 1 | 675 | cg26509254 | chr6:30685303 | MDC1 | 0.0055 | 8.6E-06 |
| Hoang | 34516295 | DNA methylation | metolachlor | whole blood | discovery | 507 | cg23590244 | chr6:30685311 | MDC1 | -0.0017 | 8.7E-06 |
| Gross AM | 27105112 | DNA methylation | HIV infection | CD4+ T-cells | CD4+ T-cells | 60 | cg07257768 | chr6:30684736 | MDC1 | -0.310665 | 9.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P36955 | whole blood | OSCA model 3 | 14671 | cg22724063 | chr6:30684760 | MDC1 | 0.036 | 9.9E-06 |
| Battram T | 27886173 | DNA methylation | Inflammatory bowel disease | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 | 240 | cg10277195 | chr6:30684931 | MDC1 | -0.0448 | 1E-05 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Lifetime consumption discovery | 5606 | cg11498582 | chr6:30684340 | MDC1 | NA | 1E-05 |
| Hannon E | 27572077 | DNA methylation | Schizophrenia | Whole blood | Phase 1 | 675 | cg16253551 | chr6:30685136 | MDC1 | 0.0056 | 1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P15169 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.048 | 1E-05 |
| Battram T | 27886173 | DNA methylation | Crohn's disease | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 | 161 | cg10277195 | chr6:30684931 | MDC1 | 0.057 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg03151709 | chr6:30686511 | MDC1 | -0.0362684 | 1.1E-05 |
| Liu C | 27843151 | DNA methylation | Alcohol consumption per day | Whole blood | European ancestry | 9643 | cg07257768 | chr6:30684736 | MDC1 | -0.0001528 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02760 | whole blood | OSCA model 1 | 14671 | cg03844211 | chr6:30684773 | MDC1 | 0.036 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 4 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.047 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 4 | 14671 | cg07656347 | chr6:30684837 | MDC1 | 0.038 | 1.2E-05 |
| Gadd DA | 35945220 | MYNN protein levels (SeqId = 12455-48) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.73 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | -0.036117 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P36955 | whole blood | OSCA model 3 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.039 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9Y5Y7 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.047 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | -0.0360145 | 1.3E-05 |
| Gadd DA | 35945220 | SPSB1 protein levels (SeqId = 13942-140) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.727 | 1.3E-05 |
| Gadd DA | 35945220 | UBE2B protein levels (SeqId = 9865-40) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.72 | 1.4E-05 |
| Gadd DA | 35945220 | AKR1C3 protein levels (SeqId = 17377-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.72 | 1.4E-05 |
| Gadd DA | 35945220 | ALK protein levels (SeqId = 8249-124) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.72 | 1.4E-05 |
| Gadd DA | 35945220 | PDCL2 protein levels (SeqId = 14192-31) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.72 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.036 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.036 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | -0.0356433 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.036 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0460526 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0779424 | 1.7E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg12814525 | chr6:30685250 | MDC1 | 0.14 | 1.7E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg07656347 | chr6:30684837 | MDC1 | 0.0016 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q15848 | whole blood | OSCA model 2 | 14671 | cg03844211 | chr6:30684773 | MDC1 | 0.036 | 1.8E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | ch.6.738234R | chr6:30679284 | MDC1 | -0.808404 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg03844211 | chr6:30684773 | MDC1 | 0.035 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg05546064 | chr6:30685074 | MDC1 | 0.035 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O43866 | whole blood | OSCA model 3 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0393656 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0357655 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0457592 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | 0.035 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0352849 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg03844211 | chr6:30684773 | MDC1 | -0.0354163 | 2E-05 |
| Cardenas A | 31300640 | DNA methylation | fractional exhaled nitric oxide (FeNO) | nasal epithelium | None | 517 | cg03151709 | chr6:30686511 | MDC1 | -1.42 | 2E-05 |
| Gadd DA | 35945220 | AURKA protein levels (SeqId = 3091-70) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.71 | 2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg07257768 | chr6:30684736 | MDC1 | -0.146651 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 2 | 14671 | cg03844211 | chr6:30684773 | MDC1 | 0.035 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0350735 | 2.1E-05 |
| Gadd DA | 35945220 | KLHL13 protein levels (SeqId = 12463-7) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.71 | 2.2E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg13983052 | chr6:30685120 | MDC1 | 0.00014 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.045 | 2.3E-05 |
| Gadd DA | 35945220 | BTLA protein levels (SeqId = 16308-14) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.71 | 2.3E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg18301048 | chr6:30685243 | MDC1 | 0.00043 | 2.3E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg02364450 | chr6:30671881 | MDC1 | -2.1 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0349135 | 2.3E-05 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg10925640 | chr6:30684572 | MDC1 | -0.013 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0455596 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.035 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | 0.035 | 2.5E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg22724063 | chr6:30684760 | MDC1 | -0.112768 | 2.5E-05 |
| Panni T | 26731791 | DNA methylation | Air pollution exposure | Whole blood | 28-day trailing average particle matter concentration | 2956 | cg00682802 | chr6:30682855 | MDC1 | 0.0023 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 3 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0349347 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg03844211 | chr6:30684773 | MDC1 | 0.035 | 2.6E-05 |
| Gadd DA | 35945220 | METTL1 protein levels (SeqId = 12514-16) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.7 | 2.6E-05 |
| Liu C | 27843151 | DNA methylation | Alcohol consumption per day | CD14+ monocytes | CD14+ monocytes | 1251 | cg07257768 | chr6:30684736 | MDC1 | -0.000335 | 2.6E-05 |
| Gadd DA | 35945220 | VAMP8 protein levels (SeqId = 7064-2) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.7 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg03844211 | chr6:30684773 | MDC1 | -0.0347681 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0346075 | 2.8E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg00682802 | chr6:30682855 | MDC1 | 0.0018 | 2.8E-05 |
| Gadd DA | 35945220 | CD81 protein levels (SeqId = 19612-3) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.7 | 2.8E-05 |
| Gadd DA | 35945220 | SF3B4 protein levels (SeqId = 13449-25) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23590244 | chr6:30685311 | MDC1 | -0.6 | 2.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg03151709 | chr6:30686511 | MDC1 | 0.037 | 2.8E-05 |
| Gadd DA | 35945220 | GMPR protein levels (SeqId = 19254-125) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.69 | 2.9E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg17188180 | chr6:30684840 | MDC1 | -0.876616 | 3E-05 |
| Gadd DA | 35945220 | ZDHHC14 protein levels (SeqId = 11677-17) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.7 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0348895 | 3E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg04381681 | chr6:30681593 | MDC1 | 0.001 | 3.1E-05 |
| Gadd DA | 35945220 | PRC1 protein levels (SeqId = 15310-61) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.7 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0343702 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00575529 | chr6:30685080 | MDC1 | 0.034 | 3.2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg04406101 | chr6:30670340 | MDC1 | -0.17335 | 3.3E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Basic model | 17749 | cg03844211 | chr6:30684773 | MDC1 | -0.026 | 3.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg03844211 | chr6:30684773 | MDC1 | -0.0342261 | 3.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0754173 | 3.4E-05 |
| Gadd DA | 35945220 | ZNF174 protein levels (SeqId = 11486-26) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.69 | 3.4E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg19187854 | chr6:30670795 | MDC1 | -0.210851 | 3.5E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg06315208 | chr6:30684406 | MDC1 | -1.2 | 3.6E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg05300316 | chr6:30685246 | MDC1 | 0.00026 | 3.7E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg05546064 | chr6:30685074 | MDC1 | 0.0008 | 3.7E-05 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Previous decade consumption discovery | 5606 | cg06315208 | chr6:30684406 | MDC1 | NA | 3.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02787 | whole blood | OSCA model 3 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.038 | 3.8E-05 |
| Gadd DA | 35945220 | ANGPTL1 protein levels (SeqId = 9092-33) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.69 | 3.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0339355 | 3.9E-05 |
| Gadd DA | 35945220 | PAPPA2 protein levels (SeqId = 5756-66) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.69 | 4E-05 |
| Gadd DA | 35945220 | TENM4 protein levels (SeqId = 11365-17) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.683 | 4E-05 |
| Gadd DA | 35945220 | PAPPA protein levels (SeqId = 4148-49) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02364450 | chr6:30671881 | MDC1 | 1.2 | 4E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Type 2 Diabetes | Whole blood | Basic model | 17749 | cg11498582 | chr6:30684340 | MDC1 | -0.035 | 4.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.044 | 4.1E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg05546064 | chr6:30685074 | MDC1 | 0.14 | 4.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 3 | 14671 | cg07257768 | chr6:30684736 | MDC1 | 0.034 | 4.2E-05 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg00575529 | chr6:30685080 | MDC1 | 0.0045 | 4.2E-05 |
| Gadd DA | 35945220 | AKR1C1 protein levels (SeqId = 12618-50) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.68 | 4.2E-05 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Previous week consumption discovery | 5606 | cg21105955 | chr6:30684478 | MDC1 | NA | 4.2E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | CD4+ T-cells | CD4+ T-cells | 60 | cg06315208 | chr6:30684406 | MDC1 | -0.465645 | 4.3E-05 |
| Gadd DA | 35945220 | IL27 protein levels (SeqId = 2829-19) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.681 | 4.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0374608 | 4.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg22596454 | chr6:30685146 | MDC1 | 0.24 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0374899 | 4.4E-05 |
| Gadd DA | 35945220 | TXN protein levels (SeqId = 8813-160) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.68 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0337174 | 4.4E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg06315208 | chr6:30684406 | MDC1 | -0.144783 | 4.5E-05 |
| Gadd DA | 35945220 | GCH1 protein levels (SeqId = 11185-145) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.68 | 4.6E-05 |
| Gadd DA | 35945220 | LRTM2 protein levels (SeqId = 8906-60) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.68 | 4.6E-05 |
| Gadd DA | 35945220 | TNMD protein levels (SeqId = 6578-29) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.68 | 4.7E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg15024975 | chr6:30685170 | MDC1 | 0.0016 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.037 | 4.8E-05 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Previous week consumption discovery | 5606 | cg06315208 | chr6:30684406 | MDC1 | NA | 4.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | 0.034 | 5E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg01533397 | chr6:30684278 | MDC1 | 0.004 | 5E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg26509254 | chr6:30685303 | MDC1 | 0.0017 | 5.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg03151709 | chr6:30686511 | MDC1 | -0.033409 | 5.2E-05 |
| Gadd DA | 35945220 | RPP30 protein levels (SeqId = 17511-10) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.67 | 5.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg04381681 | chr6:30681593 | MDC1 | 0.033 | 5.5E-05 |
| Gadd DA | 35945220 | LSM1 protein levels (SeqId = 17795-176) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.67 | 5.6E-05 |
| Gadd DA | 35945220 | STK17B protein levels (SeqId = 5249-31) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.67 | 5.6E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent Type 2 Diabetes (Self-report) | Whole blood | Basic model | 18005 | cg07257768 | chr6:30684736 | MDC1 | -0.051 | 5.6E-05 |
| Battram T | 30045751 | DNA methylation | Alzheimer's disease | Brain | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351 | 190 | cg21105955 | chr6:30684478 | MDC1 | 0.027 | 5.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0331951 | 5.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q15848 | whole blood | OSCA model 1 | 14671 | cg03844211 | chr6:30684773 | MDC1 | 0.033 | 5.8E-05 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Lifetime consumption discovery | 5606 | cg06315208 | chr6:30684406 | MDC1 | NA | 5.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0368404 | 5.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 3 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0737908 | 6.2E-05 |
| Gadd DA | 35945220 | FANCL protein levels (SeqId = 10063-10) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.67 | 6.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | discovery | 18270 | cg07257768 | chr6:30684736 | MDC1 | -0.109371 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg03844211 | chr6:30684773 | MDC1 | -0.0329865 | 6.4E-05 |
| Gadd DA | 35945220 | BMX protein levels (SeqId = 3414-40) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.67 | 6.5E-05 |
| Gadd DA | 35945220 | IL36B protein levels (SeqId = 14149-9) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.67 | 6.5E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent Type 2 Diabetes (Self-report) | Whole blood | Basic model | 18005 | cg03844211 | chr6:30684773 | MDC1 | -0.056 | 6.6E-05 |
| Gervin K | 28785368 | DNA methylation | Long-term prenatal exposure to paracetamol in children with ADHD versus controls | Cord blood | Long-term prenatal exposure to paracetamol versus controls | 115 | cg16253551 | chr6:30685136 | MDC1 | NA | 6.7E-05 |
| Gadd DA | 35945220 | JMJD6 protein levels (SeqId = 18322-15) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 6.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 4 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.043 | 6.9E-05 |
| Gadd DA | 35945220 | SPHK2 protein levels (SeqId = 4468-21) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 6.9E-05 |
| Gadd DA | 35945220 | PAPLN protein levels (SeqId = 11254-13) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.664 | 6.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg03844211 | chr6:30684773 | MDC1 | -0.135242 | 6.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | 0.043 | 6.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg07257768 | chr6:30684736 | MDC1 | 0.033 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg14029839 | chr6:30685271 | MDC1 | 0.033 | 7.1E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Ischemic Heart Disease | Whole blood | Basic model | 17483 | cg03844211 | chr6:30684773 | MDC1 | -0.024 | 7.1E-05 |
| Gadd DA | 35945220 | FAM173A protein levels (SeqId = 7148-42) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 7.1E-05 |
| Gadd DA | 35945220 | SIRT3 protein levels (SeqId = 17495-141) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.033 | 7.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 3 | 14671 | cg03844211 | chr6:30684773 | MDC1 | -0.0329835 | 7.3E-05 |
| Gadd DA | 35945220 | CDH15 protein levels (SeqId = 5410-53) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 7.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg23886643 | chr6:30670957 | MDC1 | -0.0327204 | 7.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg26552907 | chr6:30667625 | MDC1 | -0.0327189 | 7.4E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg11968414 | chr6:30684868 | MDC1 | 0.00049 | 7.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 3 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0362974 | 7.4E-05 |
| Gadd DA | 35945220 | CNTNAP5 protein levels (SeqId = 9044-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 7.5E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | ch.6.738234R | chr6:30679284 | MDC1 | 0.00038 | 7.5E-05 |
| Gadd DA | 35945220 | ARSK protein levels (SeqId = 8269-327) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 7.6E-05 |
| Gadd DA | 35945220 | DPYSL5 protein levels (SeqId = 12683-156) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q15848 | whole blood | OSCA model 2 | 14671 | cg07257768 | chr6:30684736 | MDC1 | 0.033 | 7.7E-05 |
| Gadd DA | 35945220 | SUSD1 protein levels (SeqId = 9582-93) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.659 | 7.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg05317081 | chr6:30685534 | MDC1 | 0.033 | 7.7E-05 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg16580700 | chr6:30685744 | MDC1 | -0.0006999 | 7.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg11498582 | chr6:30684340 | MDC1 | 0.042 | 7.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 3 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0330949 | 7.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg07129907 | chr6:30683787 | MDC1 | 0.15 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 3 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.072 | 8.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 2 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0726163 | 8.1E-05 |
| Gadd DA | 35945220 | RAB39B protein levels (SeqId = 12403-30) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 8.1E-05 |
| Gadd DA | 35945220 | PC protein levels (SeqId = 13990-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 8.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 3 | 14671 | cg26158287 | chr6:30685461 | MDC1 | -0.0327914 | 8.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 2 | 14671 | cg03844211 | chr6:30684773 | MDC1 | -0.0326937 | 8.2E-05 |
| Gadd DA | 35945220 | TBXAS1 protein levels (SeqId = 8098-37) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 8.3E-05 |
| Gadd DA | 35945220 | BNIP3 protein levels (SeqId = 7045-4) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 8.3E-05 |
| Gadd DA | 35945220 | MANBA protein levels (SeqId = 6382-17) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23590244 | chr6:30685311 | MDC1 | -0.57 | 8.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 3 | 14671 | cg02364450 | chr6:30671881 | MDC1 | -0.0695635 | 8.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 4 | 14671 | cg07257768 | chr6:30684736 | MDC1 | -0.0418299 | 8.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg11498582 | chr6:30684340 | MDC1 | -0.0324393 | 8.5E-05 |
| Gadd DA | 35945220 | CUL9 protein levels (SeqId = 12991-49) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 8.6E-05 |
| Gadd DA | 35945220 | TPP1 protein levels (SeqId = 17691-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 8.6E-05 |
| Gadd DA | 35945220 | AQP4 protein levels (SeqId = 11363-58) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.66 | 8.6E-05 |
| Gadd DA | 35945220 | CPT1B protein levels (SeqId = 11709-29) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 8.8E-05 |
| Joehanes R | 27651444 | DNA methylation | Current versus never smoking | Whole blood, CD4+ T cells or monocytes | Current vs never smoking | 9389 | cg03844211 | chr6:30684773 | MDC1 | -0.0036 | 8.9E-05 |
| Gadd DA | 35945220 | AGR2 protein levels (SeqId = 4959-2) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 9E-05 |
| Gadd DA | 35945220 | FAM162B protein levels (SeqId = 11163-7) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 9E-05 |
| Gadd DA | 35945220 | CHST6 protein levels (SeqId = 4429-51) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 9.1E-05 |
| Gadd DA | 35945220 | SYNJ2BP protein levels (SeqId = 17348-5) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23590244 | chr6:30685311 | MDC1 | -0.562 | 9.1E-05 |
| Gadd DA | 35945220 | SERF1A protein levels (SeqId = 7842-52) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 9.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O43866 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0420613 | 9.2E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg03151709 | chr6:30686511 | MDC1 | 0.0014 | 9.4E-05 |
| Gadd DA | 35945220 | KPNA4 protein levels (SeqId = 12698-72) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 9.4E-05 |
| Gadd DA | 35945220 | SUFU protein levels (SeqId = 17468-1) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 9.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0417003 | 9.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 1 | 14671 | cg02364450 | chr6:30671881 | MDC1 | 0.032 | 9.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg07656347 | chr6:30684837 | MDC1 | 0.032 | 9.6E-05 |
| Gadd DA | 35945220 | CALR protein levels (SeqId = 5264-65) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 9.6E-05 |
| Gadd DA | 35945220 | ASTL protein levels (SeqId = 7993-23) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 9.6E-05 |
| Gadd DA | 35945220 | ASIC4 protein levels (SeqId = 6951-26) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg07229198 | chr6:30685635 | MDC1 | -0.65 | 9.7E-05 |
| Gadd DA | 35945220 | QPCT protein levels (SeqId = 7849-3) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg26509254 | chr6:30685303 | MDC1 | -0.68 | 9.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg23886643 | chr6:30670957 | MDC1 | -0.0321438 | 9.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH35 | whole blood | OSCA model 3 | 14671 | cg06315208 | chr6:30684406 | MDC1 | -0.0418166 | 9.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg16253551 | chr6:30685136 | MDC1 | 0.2 | 1E-04 |
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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.
