Search results for MTHFR
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg17514528 | chr1:11862907 | MTHFR | -0.012 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg17514528 | chr1:11862907 | MTHFR | 0.029 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg17745097 | chr1:11863365 | MTHFR | -0.0031 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg17745097 | chr1:11863365 | MTHFR | 0.01 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg22877851 | chr1:11847167 | MTHFR | 0.0016 | 0E+00 |
| Mandaviya PR | 29084233 | DNA methylation | homocysteine (MTHFR 677C>T) | Whole blood | Meta-analysis | 9894 | cg17514528 | chr1:11862907 | MTHFR | 0.02 | 1E-154 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg21864959 | chr1:11847863 | MTHFR | 0.54 | 1.8E-133 |
| Mandaviya PR | 29084233 | DNA methylation | homocysteine (MTHFR 677C>T) | Whole blood | Meta-analysis | 9894 | cg17745097 | chr1:11863365 | MTHFR | 0.007 | 1.3E-113 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg23088157 | chr1:11851316 | MTHFR | 0.21 | 3.2E-113 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg17514528 | chr1:11862907 | MTHFR | NA | 1.4E-96 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg17745097 | chr1:11863365 | MTHFR | 0.13 | 1E-83 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg17514528 | chr1:11862907 | MTHFR | 0.22 | 3.1E-74 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg17745097 | chr1:11863365 | MTHFR | NA | 5.4E-58 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg23088157 | chr1:11851316 | MTHFR | NA | 1.5E-55 |
| Mandaviya PR | 29084233 | DNA methylation | homocysteine (MTHFR 677C>T) | Whole blood | Meta-analysis | 9894 | cg21864959 | chr1:11847863 | MTHFR | -0.006 | 1.2E-50 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.121164 | 4.2E-49 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.106876 | 1.6E-38 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg17745097 | chr1:11863365 | MTHFR | -2.03055 | 4.3E-32 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg17514528 | chr1:11862907 | MTHFR | 0.25 | 5E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0691391 | 5.1E-17 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg17745097 | chr1:11863365 | MTHFR | -0.0010508 | 4.9E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.065 | 4.9E-15 |
| Mandaviya PR | 29084233 | DNA methylation | homocysteine GRS | Whole blood | Meta-analysis | 9894 | cg17514528 | chr1:11862907 | MTHFR | 0.022 | 6.4E-14 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg17514528 | chr1:11862907 | MTHFR | 0.23 | 1.2E-13 |
| Nones K | 24500968 | DNA methylation | Pancreatic ductal adenocarcinoma | Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata | - | 196 | cg17745097 | chr1:11863365 | MTHFR | NA | 1.5E-13 |
| Kyung WK | 32795589 | DNA methylation | atopy | nasal polyp | discovery | 108 | cg22877851 | chr1:11847167 | MTHFR | 0.028 | 2.9E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0601163 | 3.2E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg20620484 | chr1:11858027 | MTHFR | -0.0599715 | 3.6E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg18276943 | chr1:11853610 | MTHFR | 0.00059 | 1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0579752 | 2.1E-12 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg22877851 | chr1:11847167 | MTHFR | -0.0091 | 1.3E-11 |
| Kyung WK | 32795589 | DNA methylation | eosinophilia | nasal polyp | discovery | 129 | cg07980026 | chr1:11858064 | MTHFR | -0.061 | 2.2E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg20620484 | chr1:11858027 | MTHFR | -0.0549514 | 2.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0549423 | 2.8E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0537384 | 7.4E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg17514528 | chr1:11862907 | MTHFR | 0.19 | 1.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.052965 | 1.4E-10 |
| Li S | 28811542 | DNA methylation | Age | Whole blood | - | 1366 | cg17514528 | chr1:11862907 | MTHFR | -0.0124 | 3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg20620484 | chr1:11858027 | MTHFR | -0.0512417 | 5.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.051 | 6.1E-10 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg17514528 | chr1:11862907 | MTHFR | 0.18 | 6.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0535878 | 1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 2 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.062 | 1.4E-09 |
| Mandaviya PR | 29084233 | DNA methylation | homocysteine (MTHFR 677C>T) | Whole blood | Meta-analysis | 9894 | cg18276943 | chr1:11853610 | MTHFR | 0.001 | 1.6E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | sensitivity | 17304 | cg17514528 | chr1:11862907 | MTHFR | 0.19 | 2.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.049 | 2.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg07980026 | chr1:11858064 | MTHFR | -0.0490471 | 2.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0525452 | 2.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg15861278 | chr1:11863490 | MTHFR | -0.0483538 | 4.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0476402 | 7.8E-09 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg17514528 | chr1:11862907 | MTHFR | 0.18 | 8.5E-09 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg17514528 | chr1:11862907 | MTHFR | NA | 9.8E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0468338 | 1.4E-08 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg17514528 | chr1:11862907 | MTHFR | -0.0008722 | 1.8E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg21864959 | chr1:11847863 | MTHFR | -0.0067 | 2.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0485924 | 2.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0489118 | 2.8E-08 |
| Kyung WK | 32795589 | DNA methylation | atopy | nasal polyp | discovery | 108 | cg15861278 | chr1:11863490 | MTHFR | -0.013 | 2.8E-08 |
| Demerath EW | 25935004 | DNA methylation | Waist circumference | Leukocytes | Discovery | 2097 | cg17514528 | chr1:11862907 | MTHFR | 0.01 | 3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.045707 | 3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0478665 | 4.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.045 | 5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.045 | 5.2E-08 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg17514528 | chr1:11862907 | MTHFR | 0.12 | 5.2E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg18276943 | chr1:11853610 | MTHFR | 0.0019 | 8.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0438203 | 1.1E-07 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Ultrasound-estimated gestational age | 1068 | cg17745097 | chr1:11863365 | MTHFR | -0.00070029 | 1.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0463701 | 1.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0434579 | 1.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg07980026 | chr1:11858064 | MTHFR | -0.0431339 | 1.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg15861278 | chr1:11863490 | MTHFR | -0.0444671 | 1.8E-07 |
| Mandaviya PR | 29084233 | DNA methylation | homocysteine GRS | Whole blood | Meta-analysis | 9894 | cg17745097 | chr1:11863365 | MTHFR | 0.006 | 1.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0429874 | 1.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg15861278 | chr1:11863490 | MTHFR | -0.0436018 | 3.1E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg23088157 | chr1:11851316 | MTHFR | 0.0011 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0420087 | 3.6E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg23088157 | chr1:11851316 | MTHFR | -0.00082 | 4.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.042 | 4.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0416912 | 4.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg17745097 | chr1:11863365 | MTHFR | -0.041502 | 4.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | 0.041 | 6.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg15861278 | chr1:11863490 | MTHFR | -0.0422047 | 7.1E-07 |
| Singmann P | 26500701 | DNA methylation | Sex | Whole blood | KORA F4 | 1799 | cg17745097 | chr1:11863365 | MTHFR | NA | 7.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0495583 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | 0.04 | 1.3E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg17514528 | chr1:11862907 | MTHFR | 0.0094 | 1.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg20620484 | chr1:11858027 | MTHFR | -0.0397606 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.039723 | 1.5E-06 |
| Battram T | 23177740 | DNA methylation | Age | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279 | 656 | cg17514528 | chr1:11862907 | MTHFR | -0.00077 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0487145 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg07980026 | chr1:11858064 | MTHFR | -0.0393416 | 1.9E-06 |
| Battram T | 23177740 | DNA methylation | Age | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279 | 656 | cg17745097 | chr1:11863365 | MTHFR | -0.00036 | 2.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 2 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0415254 | 2.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg07980026 | chr1:11858064 | MTHFR | -0.0386786 | 2.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 2 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.047 | 3.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg15861278 | chr1:11863490 | MTHFR | -0.0394085 | 3.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0468254 | 3.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0380766 | 4E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg23088157 | chr1:11851316 | MTHFR | -0.179704 | 4.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg15861278 | chr1:11863490 | MTHFR | -0.0379989 | 4.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg20620484 | chr1:11858027 | MTHFR | 0.038 | 4.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0377995 | 4.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 2 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.047 | 4.7E-06 |
| Joehanes R | 27651444 | DNA methylation | Current versus never smoking | Whole blood, CD4+ T cells or monocytes | Current vs never smoking | 9389 | cg17514528 | chr1:11862907 | MTHFR | -0.0068 | 4.9E-06 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg17514528 | chr1:11862907 | MTHFR | -0.00682 | 4.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | 0.037 | 5.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 3 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0394654 | 7.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg20620484 | chr1:11858027 | MTHFR | -0.0393541 | 8.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg20620484 | chr1:11858027 | MTHFR | 0.037 | 8.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg20620484 | chr1:11858027 | MTHFR | -0.0366575 | 8.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg20620484 | chr1:11858027 | MTHFR | -0.0366365 | 9.1E-06 |
| Aghagoli G | 32967004 | cry acoustics factor 1 | DNA methylation | Buccal | None | 335 | cg11544334 | chr1:11863812 | MTHFR | -0.001 | 9.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 4 | 14671 | cg15861278 | chr1:11863490 | MTHFR | -0.0450396 | 9.2E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg16673660 | chr1:11855302 | MTHFR | -0.175033 | 9.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg20620484 | chr1:11858027 | MTHFR | -0.0391155 | 9.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg17745097 | chr1:11863365 | MTHFR | -0.0368324 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0383969 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.036 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P07996 | whole blood | OSCA model 3 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0380029 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0356395 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.043661 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0353953 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 4 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0573736 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | 0.035 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0432738 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH34 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | 0.035 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.043 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0347117 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01714 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | 0.035 | 2.6E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg23088157 | chr1:11851316 | MTHFR | 0.0034 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg19180348 | chr1:11863898 | MTHFR | 0.037 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg17745097 | chr1:11863365 | MTHFR | -0.0350644 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q16610 | whole blood | OSCA model 4 | 14671 | cg21864959 | chr1:11847863 | MTHFR | -0.0372616 | 3.8E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg17514528 | chr1:11862907 | MTHFR | -0.116976 | 3.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg25730859 | chr1:11863974 | MTHFR | -0.0338569 | 4.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0360832 | 4.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg15861278 | chr1:11863490 | MTHFR | -0.0335485 | 4.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P07996 | whole blood | OSCA model 2 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0356582 | 5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0334314 | 5.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg17514528 | chr1:11862907 | MTHFR | -0.0333528 | 5.3E-05 |
| Sharp G | 33517419 | DNA methylation | Maternal body mass index | Cord blood | Adjusted for paternal BMI using cord blood | 4894 | cg17745097 | chr1:11863365 | MTHFR | 0.0025 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 4 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0470442 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q08380 | whole blood | OSCA model 2 | 14671 | cg17514528 | chr1:11862907 | MTHFR | 0.041 | 6.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P07996 | whole blood | OSCA model 1 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0328104 | 7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg23088157 | chr1:11851316 | MTHFR | -0.0327865 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg07980026 | chr1:11858064 | MTHFR | -0.0327649 | 7.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00581063 | chr1:11863389 | MTHFR | -0.0327634 | 7.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01701 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | 0.033 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01700 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | 0.033 | 7.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | 0.032 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg15861278 | chr1:11863490 | MTHFR | -0.0323893 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg19180348 | chr1:11863898 | MTHFR | -0.0323307 | 9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg17745097 | chr1:11863365 | MTHFR | -0.033135 | 9.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg21864959 | chr1:11847863 | MTHFR | 0.032 | 9.5E-05 |
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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.
