EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for NOD2

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg01020263 chr16:50732073 NOD2 -0.02 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg01020263 chr16:50732073 NOD2 0.064 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg01068906 chr16:50745944 NOD2 -0.0041 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg01068906 chr16:50745944 NOD2 0.015 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg01243823 chr16:50732212 NOD2 -0.016 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg01243823 chr16:50732212 NOD2 0.043 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg02119982 chr16:50731412 NOD2 0.0012 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08195491 chr16:50746063 NOD2 -0.0017 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08554257 chr16:50730737 NOD2 -0.002 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg18177814 chr16:50730881 NOD2 -0.0029 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg26954174 chr16:50730813 NOD2 -0.0027 0E+00
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg01020263 chr16:50732073 NOD2 NA 1.8E-145
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg26954174 chr16:50730813 NOD2 0.43 2.3E-145
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg08554257 chr16:50730737 NOD2 0.37 1.2E-126
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg02486161 chr16:50766599 NOD2 0.36 2E-123
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg01068906 chr16:50745944 NOD2 0.21 6.5E-112
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg01243823 chr16:50732212 NOD2 NA 8.6E-107
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg00641052 chr16:50753673 NOD2 0.35 1E-106
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg18177814 chr16:50730881 NOD2 0.38 1.5E-101
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.168305 1.1E-93
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.166063 3.3E-91
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg05261686 chr16:50743296 NOD2 -0.24992 5.8E-90
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg06181567 chr16:50731115 NOD2 0.35 1.2E-82
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.154526 4.4E-79
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.153794 2.4E-78
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg04172533 chr16:50743027 NOD2 -0.22154 7E-78
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg01243823 chr16:50732212 NOD2 -0.458748 2.1E-75
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg16771652 chr16:50730385 NOD2 -0.16853 2.5E-74
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.146444 3.9E-71
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg26954174 chr16:50730813 NOD2 NA 1.9E-70
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.145241 5.5E-70
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.145102 7.5E-70
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg08195491 chr16:50746063 NOD2 0.15 2.1E-68
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg01243823 chr16:50732212 NOD2 -3.5 8.7E-67
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg18177814 chr16:50730881 NOD2 NA 2.2E-64
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg01020263 chr16:50732073 NOD2 NA 7.6E-62
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg01243823 chr16:50732212 NOD2 -0.415532 8.2E-62
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg01055281 chr16:50746052 NOD2 0.13 6.7E-61
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.134539 3.2E-60
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.132217 3.3E-58
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg08554257 chr16:50730737 NOD2 NA 1.8E-55
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.128941 2E-55
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.12863 3.7E-55
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg06181567 chr16:50731115 NOD2 NA 3.7E-55
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg01243823 chr16:50732212 NOD2 -0.456536 7.6E-53
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.123695 4.1E-51
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.122643 2.8E-50
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg01020263 chr16:50732073 NOD2 4.4 5E-50
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.121694 1.6E-49
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.120106 2.8E-48
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg01243823 chr16:50732212 NOD2 -0.436217 9E-48
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.119214 1.4E-47
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.118257 7.7E-47
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg01020263 chr16:50732073 NOD2 -0.312594 4E-46
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg01243823 chr16:50732212 NOD2 -1.27960825 7.9E-46
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.116123 3.2E-45
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg02448735 chr16:50744993 NOD2 0.043 2.4E-44
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.114665 4E-44
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.110057 9E-41
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg08554257 chr16:50730737 NOD2 -1.28810092 3.2E-40
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg01243823 chr16:50732212 NOD2 -0.3302 8.3E-40
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg08554257 chr16:50730737 NOD2 -0.338246 5E-39
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.105909 7.3E-38
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.105347 1.8E-37
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.105154 2.4E-37
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.104121 1.2E-36
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.103866 1.8E-36
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.103558 2.9E-36
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.103337 4E-36
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.101124 1.2E-34
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg01020263 chr16:50732073 NOD2 -0.96946109 1.3E-34
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg18177814 chr16:50730881 NOD2 -0.51346 2.3E-34
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0991247 2.3E-33
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg01243823 chr16:50732212 NOD2 -0.08611 2.4E-33
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg05261686 chr16:50743296 NOD2 -1.81754 1.1E-32
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg08554257 chr16:50730737 NOD2 NA 6.6E-32
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg01020263 chr16:50732073 NOD2 -0.258209 8E-32
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0957599 3.1E-31
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg01020263 chr16:50732073 NOD2 -0.10451 1.2E-30
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0927298 2.2E-29
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg04172533 chr16:50743027 NOD2 -1.95185 6.9E-29
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0914829 1.2E-28
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.090618 3.9E-28
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0900842 8E-28
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg26954174 chr16:50730813 NOD2 -1.07383284 8.4E-28
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.09 9E-28
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0895198 1.7E-27
Nones K 24500968 DNA methylation Pancreatic ductal adenocarcinoma Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata - 196 cg26954174 chr16:50730813 NOD2 NA 4E-27
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg18177814 chr16:50730881 NOD2 -0.453821 4.5E-27
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg01020263 chr16:50732073 NOD2 -3.1 7.2E-27
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg08195491 chr16:50746063 NOD2 NA 1.2E-26
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg08554257 chr16:50730737 NOD2 -0.276471 1.3E-26
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg16771652 chr16:50730385 NOD2 -0.00966 1.9E-26
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg18177814 chr16:50730881 NOD2 -3.0 5.8E-26
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg01243823 chr16:50732212 NOD2 -0.315685 6.2E-26
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.086546 8.5E-26
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0859486 1.8E-25
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg08554257 chr16:50730737 NOD2 1.5 1.8E-25
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.087 2.2E-25
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.085 4.2E-25
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg01020263 chr16:50732073 NOD2 -0.226191 6.3E-25
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.085 1E-24
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.084389 1.3E-24
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.083 5.4E-24
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg08554257 chr16:50730737 NOD2 -0.259868 1.4E-23
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0835155 1.5E-23
Wahl S 28002404 Body mass index DNA methylation Whole blood Discovery and replication 10238 cg01243823 chr16:50732212 NOD2 NA 2.4E-23
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg08554257 chr16:50730737 NOD2 -3.0 1.8E-22
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0806219 2.3E-22
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0799592 3E-22
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.08 4.3E-22
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg18177814 chr16:50730881 NOD2 -0.81811109 4.9E-22
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0793366 6.3E-22
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg26954174 chr16:50730813 NOD2 -0.288418 6.8E-22
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.079 1.6E-21
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg01020263 chr16:50732073 NOD2 -0.246429 3E-21
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0776356 4.6E-21
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg08195491 chr16:50746063 NOD2 0.0012 5.8E-21
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg18177814 chr16:50730881 NOD2 -0.480628 1.3E-20
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg18177814 chr16:50730881 NOD2 -0.476435 1.6E-20
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg26954174 chr16:50730813 NOD2 -0.277363 2.5E-20
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0761091 2.7E-20
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg05823465 chr16:50744999 NOD2 0.0014 4E-20
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg08554257 chr16:50730737 NOD2 -0.0015091 4.6E-20
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0755431 5.1E-20
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.075 5.5E-20
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.075 6.3E-20
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0763531 7.4E-20
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.075 9.7E-20
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0749588 9.8E-20
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0746182 1.4E-19
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0741367 2.4E-19
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0737474 3.8E-19
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0723329 1.8E-18
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 0.096 1.8E-18
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 3660175 (gene symbol: NOD2) Whole blood Meta-analysis 4170 cg04172533 chr16:50743027 NOD2 NA 3.5E-18
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.071 4.7E-18
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg01243823 chr16:50732212 NOD2 -0.044 5.6E-18
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0712484 5.6E-18
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg01243823 chr16:50732212 NOD2 0.21 6.2E-18
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.072 1E-17
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0706622 1E-17
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0702721 1.6E-17
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.07 1.7E-17
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0701913 1.7E-17
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 0.091 3.3E-17
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0695033 3.5E-17
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.069 4.4E-17
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0702356 4.5E-17
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.069088 5.4E-17
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0690177 5.8E-17
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0687366 7.8E-17
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.068 1E-16
Bohlin J 27717397 DNA methylation Gestational age Cord blood Ultrasound-estimated gestational age 1068 cg01068906 chr16:50745944 NOD2 -0.00066853 1.3E-16
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 -0.06794 1.8E-16
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg01068906 chr16:50745944 NOD2 -0.0007144 1.8E-16
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0672389 3.6E-16
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0671983 3.7E-16
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08848643 chr16:50745102 NOD2 -0.0018 4.4E-16
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg26954174 chr16:50730813 NOD2 -2.9 4.5E-16
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg26954174 chr16:50730813 NOD2 -0.041 5.8E-16
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.067 6.2E-16
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg08848643 chr16:50745102 NOD2 0.0018 1.1E-15
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0659738 1.3E-15
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg01020263 chr16:50732073 NOD2 -0.209569 1.3E-15
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg26954174 chr16:50730813 NOD2 -0.00140054 1.5E-15
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0656558 1.7E-15
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg16901027 chr16:50730221 NOD2 -0.041 1.8E-15
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg08554257 chr16:50730737 NOD2 -0.035 2.3E-15
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg08554257 chr16:50730737 NOD2 -0.092 2.5E-15
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.065 2.9E-15
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0656012 3.5E-15
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.065 3.9E-15
Wahl S 28002404 Body mass index DNA methylation Whole blood European ancestry discovery 2707 cg01243823 chr16:50732212 NOD2 -13.44 4.2E-15
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg26954174 chr16:50730813 NOD2 -0.235711 4.8E-15
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg08554257 chr16:50730737 NOD2 -0.041 5.1E-15
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0644785 5.4E-15
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0644561 5.5E-15
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 0.066 6.4E-15
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0638137 1E-14
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.064 1.1E-14
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 -0.0844552 1.2E-14
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.064 1.3E-14
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0635421 1.3E-14
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.063 1.4E-14
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg05146293 chr16:50733800 NOD2 -0.453307 1.9E-14
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg01020263 chr16:50732073 NOD2 0.16 2.1E-14
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.062908 2.4E-14
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0627501 2.8E-14
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.062 3.8E-14
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.062 3.8E-14
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg01243823 chr16:50732212 NOD2 1.3 4E-14
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg05146293 chr16:50733800 NOD2 0.069 4.3E-14
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.062 4.3E-14
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0622014 4.7E-14
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0620282 5.5E-14
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0620226 5.5E-14
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0620016 5.6E-14
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.062 5.9E-14
Imgenberg-Kreuz J 26857698 DNA methylation Primary Sjogrens syndrome Whole blood Whole blood 500 cg04172533 chr16:50743027 NOD2 NA 6.5E-14
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 -0.0617637 7E-14
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg01243823 chr16:50732212 NOD2 -0.0096 7.1E-14
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.062 7.3E-14
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg01243823 chr16:50732212 NOD2 -0.032 8.1E-14
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg05261686 chr16:50743296 NOD2 0.0019 8.3E-14
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg01020263 chr16:50732073 NOD2 -0.033 9.9E-14
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.061 1E-13
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg01242833 chr16:50760257 NOD2 -0.312329 1.4E-13
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg01068906 chr16:50745944 NOD2 -0.268765 1.5E-13
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0608894 1.6E-13
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.061 1.6E-13
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg01068906 chr16:50745944 NOD2 -0.269906 1.6E-13
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.061 1.7E-13
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg01068906 chr16:50745944 NOD2 0.26 1.9E-13
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg04172533 chr16:50743027 NOD2 -0.00607 2E-13
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0605816 2.1E-13
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg01243823 chr16:50732212 NOD2 NA 2.3E-13
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.06 2.5E-13
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.06 2.5E-13
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0602794 2.7E-13
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg01068906 chr16:50745944 NOD2 -0.1576 3.3E-13
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0600481 3.4E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg01055281 chr16:50746052 NOD2 -0.0015 4.4E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg06181567 chr16:50731115 NOD2 0.00081 4.8E-13
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 0.06 5.4E-13
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg18177814 chr16:50730881 NOD2 -0.302998 5.6E-13
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.06 6.1E-13
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.059 6.5E-13
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.059 6.5E-13
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0592819 6.7E-13
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0592106 7.1E-13
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 0.061 7.5E-13
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 -0.078257 7.6E-13
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0591276 7.6E-13
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.059 7.9E-13
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0590724 8E-13
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 -0.0771772 1.1E-12
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.058 1.6E-12
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0582337 1.7E-12
Wahl S 28002404 Body mass index DNA mehtylation Whole blood All ancestry discovery 5387 cg01243823 chr16:50732212 NOD2 -13.8 1.7E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 -0.0757934 2E-12
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0579882 2.1E-12
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg26954174 chr16:50730813 NOD2 0.076 2.1E-12
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 -0.0760968 2.2E-12
Wahl S 28002404 Body mass index DNA methylation Whole blood All ancestry replication 4851 cg01243823 chr16:50732212 NOD2 -8.4 2.2E-12
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.058 2.3E-12
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 -0.0750586 2.6E-12
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg24330955 chr16:50752131 NOD2 0.27 2.6E-12
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.058 2.7E-12
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 0.071 3.1E-12
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0575313 3.1E-12
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.058 3.1E-12
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.057284 3.8E-12
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0571952 4.1E-12
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg26954174 chr16:50730813 NOD2 1.3 4.3E-12
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg01243823 chr16:50732212 NOD2 -0.078 4.6E-12
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.057 4.8E-12
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0568726 5.4E-12
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.058 6E-12
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg04172533 chr16:50743027 NOD2 -0.051 6E-12
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg08554257 chr16:50730737 NOD2 0.075 6.1E-12
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0567065 6.3E-12
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0573238 7.3E-12
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0565162 7.4E-12
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.057 7.5E-12
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.056 8E-12
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg08398764 chr16:50747670 NOD2 -0.036 8E-12
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0560015 1.1E-11
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0558774 1.3E-11
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg16901027 chr16:50730221 NOD2 -0.203833 1.4E-11
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 0.074 1.4E-11
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0557728 1.4E-11
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.056 1.4E-11
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.056 1.5E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.056 1.5E-11
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.056 1.6E-11
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg05823465 chr16:50744999 NOD2 -0.0011 1.6E-11
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.056 1.7E-11
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg01243823 chr16:50732212 NOD2 -1.4 1.7E-11
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0564019 1.7E-11
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg00796233 chr16:50740268 NOD2 -0.399976 1.8E-11
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 0.055 1.9E-11
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0552008 2.2E-11
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.055 2.4E-11
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg26954174 chr16:50730813 NOD2 -0.09 2.4E-11
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0550737 2.5E-11
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 -0.0550682 2.5E-11
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 0.055 2.5E-11
Kyung WK 32795589 DNA methylation atopy nasal polyp discovery 108 cg08398764 chr16:50747670 NOD2 -0.032 2.6E-11
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 -0.0550002 2.6E-11
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 -0.0677483 2.7E-11
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.055 2.9E-11
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0548527 3E-11
Kyung WK 32795589 DNA methylation atopy nasal polyp discovery 108 cg06181567 chr16:50731115 NOD2 0.038 3.1E-11
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.055 3.1E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 -0.0545586 3.8E-11
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg01020263 chr16:50732073 NOD2 -0.172398 4.2E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg11466773 chr16:50755855 NOD2 0.054 4.4E-11
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg16771652 chr16:50730385 NOD2 -0.037 4.5E-11
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg11466773 chr16:50755855 NOD2 -0.0543433 4.5E-11
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.054 4.7E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 -0.0715019 5.2E-11
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.054 6.2E-11
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.054 6.6E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg11466773 chr16:50755855 NOD2 -0.0537171 7.5E-11
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg18177814 chr16:50730881 NOD2 -0.00067095 7.6E-11
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg08554257 chr16:50730737 NOD2 -0.0066 8.1E-11
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg24330955 chr16:50752131 NOD2 -0.0536118 8.2E-11
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg26954174 chr16:50730813 NOD2 -0.039 8.3E-11
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0535851 8.3E-11
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.053 9.9E-11
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0530258 1.3E-10
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg08554257 chr16:50730737 NOD2 -0.0705654 1.3E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.053 1.4E-10
Kyung WK 32795589 DNA methylation atopy nasal polyp discovery 108 cg19513593 chr16:50731011 NOD2 0.044 1.4E-10
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg19513593 chr16:50731011 NOD2 0.041 1.4E-10
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.053 1.4E-10
Dugue PA 31552803 DNA methylation Smoking Whole blood Current vs never smoking 1851 cg01243823 chr16:50732212 NOD2 -0.12 1.5E-10
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.053 1.5E-10
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.053 1.6E-10
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0527714 1.6E-10
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.053 1.7E-10
Battram T 23177740 DNA methylation Age Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279 656 cg01243823 chr16:50732212 NOD2 -0.0011 1.8E-10
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg24330955 chr16:50752131 NOD2 1.5 1.8E-10
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 -0.0688305 1.9E-10
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg05261686 chr16:50743296 NOD2 -0.00862 1.9E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 -0.0533899 2.1E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg02448735 chr16:50744993 NOD2 -0.0012 2.3E-10
Ligthart S 27955697 DNA methylation C-reactive protein Whole blood Discovery 8863 cg01243823 chr16:50732212 NOD2 -0.0038 2.3E-10
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.052 2.4E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg16771652 chr16:50730385 NOD2 -0.0690486 2.5E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg02486161 chr16:50766599 NOD2 -0.0016 2.7E-10
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0519875 3E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 -0.0519554 3.2E-10
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.052 3.4E-10
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 0.068 3.6E-10
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg05146293 chr16:50733800 NOD2 0.057 3.7E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg04172533 chr16:50743027 NOD2 -0.0012 3.9E-10
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg01068906 chr16:50745944 NOD2 -0.0515368 4.2E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.052 4.3E-10
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.052 4.3E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg01068906 chr16:50745944 NOD2 -0.0512983 5.1E-10
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.052 5.6E-10
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0511203 5.8E-10
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.051 6E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 0.067 6.2E-10
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg03824868 chr16:50744353 NOD2 -0.01028 6.5E-10
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.051 6.5E-10
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0515684 7.7E-10
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 -0.0659238 8.6E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.0505299 8.8E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg01402665 chr16:50746924 NOD2 -0.094801 9E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg05823465 chr16:50744999 NOD2 0.0043 9.2E-10
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.05 1.1E-09
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.05 1.2E-09
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg01243823 chr16:50732212 NOD2 -0.181562 1.2E-09
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0509081 1.2E-09
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg05146293 chr16:50733800 NOD2 0.053 1.2E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg18177814 chr16:50730881 NOD2 -0.044 1.3E-09
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.05 1.3E-09
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0499844 1.4E-09
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.05 1.5E-09
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg26954174 chr16:50730813 NOD2 -0.0654799 1.5E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.05 1.7E-09
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg16901027 chr16:50730221 NOD2 -3.1 1.7E-09
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.05 1.8E-09
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.05 2E-09
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg16771652 chr16:50730385 NOD2 -2.1 2E-09
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.0498865 2.1E-09
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.049446 2.1E-09
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg11466773 chr16:50755855 NOD2 -0.0494336 2.1E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg01402665 chr16:50746924 NOD2 -0.094453 2.1E-09
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.049 2.2E-09
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.049 2.3E-09
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg26954174 chr16:50730813 NOD2 0.17 2.3E-09
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0492748 2.4E-09
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg01243823 chr16:50732212 NOD2 0.17 2.4E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.049 2.5E-09
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.049 2.8E-09
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.049 3E-09
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg08554257 chr16:50730737 NOD2 0.15 3.4E-09
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.049 3.5E-09
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0494851 3.5E-09
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg24330955 chr16:50752131 NOD2 0.052 3.8E-09
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.049 3.8E-09
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0485772 3.9E-09
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0485479 4E-09
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.0489462 4.3E-09
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0484328 4.4E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg18177814 chr16:50730881 NOD2 -0.05 4.4E-09
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.048 4.4E-09
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 0.06 4.5E-09
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 0.05 5E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.048 5.6E-09
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 0.049 5.8E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0480474 5.8E-09
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.048 6.5E-09
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0478332 6.8E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.048 7.5E-09
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.048 7.7E-09
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0476446 7.8E-09
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg01068906 chr16:50745944 NOD2 0.048 8E-09
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg01020263 chr16:50732073 NOD2 -1.104304 8.3E-09
Mendelson MM 28095459 DNA methylation Body mass index Whole blood Meta-analysis 3743 cg01243823 chr16:50732212 NOD2 NA 8.5E-09
Tajuddin SM 31426852 DNA methylation Age Whole Blood In African American individuals 237 cg01243823 chr16:50732212 NOD2 -0.018 8.6E-09
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg01020263 chr16:50732073 NOD2 -0.025 8.7E-09
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.047 8.8E-09
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.047 8.8E-09
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.047456 8.9E-09
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.047 9.5E-09
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 0.047 9.7E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg06181567 chr16:50731115 NOD2 -0.00059 1E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.048 1E-08
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0472455 1E-08
Cardenas A 31300640 DNA methylation fractional exhaled nitric oxide (FeNO) nasal epithelium None 517 cg01402665 chr16:50746924 NOD2 3.1 1.1E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 0.047 1.3E-08
Imboden M 31073081 DNA methylation FEV1 Whole blood Meta-analysis 5370 cg01243823 chr16:50732212 NOD2 0.82 1.3E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Rheumatoid Arthritis (Self-report) Whole blood Basic model 18055 cg01243823 chr16:50732212 NOD2 -0.053 1.3E-08
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg05823465 chr16:50744999 NOD2 0.052 1.3E-08
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg16771652 chr16:50730385 NOD2 -0.187577 1.4E-08
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.047 1.4E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg01242833 chr16:50760257 NOD2 0.25 1.4E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg01068906 chr16:50745944 NOD2 -0.193953 1.4E-08
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0467982 1.4E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.047 1.4E-08
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.047 1.6E-08
Dugue PA 31552803 DNA methylation Smoking Whole blood Current vs never smoking 1851 cg18177814 chr16:50730881 NOD2 -0.06 1.7E-08
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 0.046 1.8E-08
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.046 1.9E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg05146293 chr16:50733800 NOD2 -0.35734 2.1E-08
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 0.046 2.2E-08
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 -0.046155 2.2E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0461134 2.3E-08
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg18177814 chr16:50730881 NOD2 NA 2.4E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.046 2.4E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.046 2.5E-08
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg01243823 chr16:50732212 NOD2 -0.0526737 2.5E-08
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg01068906 chr16:50745944 NOD2 -0.190754 2.6E-08
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.046 2.7E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0459005 2.7E-08
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.046 2.7E-08
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.0460224 3.1E-08
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 4 14671 cg26954174 chr16:50730813 NOD2 0.11 3.2E-08
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0455661 3.4E-08
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg18177814 chr16:50730881 NOD2 0.047 3.4E-08
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.046 3.4E-08
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.045 3.5E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg02448735 chr16:50744993 NOD2 0.0013 3.6E-08
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 0.047 3.8E-08
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.045 3.8E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg08554257 chr16:50730737 NOD2 -0.174959 4.6E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg26954174 chr16:50730813 NOD2 -0.0578201 4.6E-08
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 -0.0597669 4.6E-08
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg01068906 chr16:50745944 NOD2 -0.199405 4.6E-08
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg16901027 chr16:50730221 NOD2 0.056 4.7E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg24330955 chr16:50752131 NOD2 0.21 4.9E-08
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.045 5.3E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.045 5.6E-08
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0447952 5.7E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg08554257 chr16:50730737 NOD2 -0.042 5.7E-08
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.045 5.7E-08
Wahl S 28002404 Body mass index DNA methylation Whole blood European ancestry replication 4195 cg01243823 chr16:50732212 NOD2 -6.06 5.9E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.044718 6E-08
Mendelson MM 29740313 DNA methylation Soluble tumor necrosis factor receptor 2 Whole blood None 2468 cg01243823 chr16:50732212 NOD2 -0.0135 6.2E-08
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.045242 6.4E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg02448735 chr16:50744993 NOD2 0.0045 6.6E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg26954174 chr16:50730813 NOD2 -0.077 6.6E-08
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.045 6.8E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0445027 6.9E-08
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0445003 7E-08
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0444848 7E-08
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0444578 7.2E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg26954174 chr16:50730813 NOD2 -0.048 7.2E-08
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg01068906 chr16:50745944 NOD2 0.049 7.3E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 -0.0542858 7.5E-08
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0443549 7.7E-08
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0443455 7.7E-08
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0443402 7.8E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg16771652 chr16:50730385 NOD2 -0.0575235 8.3E-08
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 0.044 8.5E-08
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.044 8.9E-08
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0441108 9E-08
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0441042 9.1E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.044 9.2E-08
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 -0.0440804 9.2E-08
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg01243823 chr16:50732212 NOD2 -0.017 9.4E-08
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0445064 1E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg19513593 chr16:50731011 NOD2 0.044 1.1E-07
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg04172533 chr16:50743027 NOD2 -0.00072618 1.1E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0438424 1.1E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.044 1.1E-07
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 -0.0437957 1.1E-07
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.044 1.2E-07
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.044 1.2E-07
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.044 1.2E-07
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.0440334 1.3E-07
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0435851 1.3E-07
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.044 1.3E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg01068906 chr16:50745944 NOD2 0.18 1.4E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.0437811 1.4E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.0437344 1.4E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg08554257 chr16:50730737 NOD2 -0.05684 1.5E-07
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.043 1.5E-07
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.043 1.6E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 -0.0443683 1.6E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg01020263 chr16:50732073 NOD2 -0.02 1.7E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 -0.0442746 1.7E-07
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 0.057 1.7E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg24330955 chr16:50752131 NOD2 0.043 1.8E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 0.044 1.8E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg16771652 chr16:50730385 NOD2 -0.172511 1.8E-07
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg11466773 chr16:50755855 NOD2 0.043 1.8E-07
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0430294 1.8E-07
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.043 1.9E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0429917 1.9E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.043 1.9E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0428318 2.1E-07
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.043 2.1E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 -0.0551738 2.2E-07
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0427656 2.2E-07
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 0.044 2.2E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.0428919 2.3E-07
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.043 2.3E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg16901027 chr16:50730221 NOD2 -0.155946 2.4E-07
Li S 28811542 DNA methylation Age Whole blood - 1366 cg01243823 chr16:50732212 NOD2 -0.00978 2.4E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 -0.0437713 2.4E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg05146293 chr16:50733800 NOD2 0.3 2.6E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 -0.042516 2.6E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg01020263 chr16:50732073 NOD2 -0.051 2.6E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0425037 2.6E-07
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0424972 2.6E-07
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.042 2.7E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Rheumatoid Arthritis (Self-report) Whole blood Basic model 18055 cg01020263 chr16:50732073 NOD2 -0.042 2.7E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg24330955 chr16:50752131 NOD2 0.045 2.7E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0423194 2.9E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg01402665 chr16:50746924 NOD2 0.081 2.9E-07
Bohlin J 27717397 DNA methylation Gestational age Cord blood Ultrasound-estimated gestational age 1068 cg08554257 chr16:50730737 NOD2 -0.00053174 2.9E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg26954174 chr16:50730813 NOD2 -0.0546291 3E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.042 3E-07
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0422303 3.1E-07
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0422237 3.1E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.042 3.2E-07
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.043 3.2E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.042 3.2E-07
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 0.056 3.3E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.042 3.4E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg08554257 chr16:50730737 NOD2 0.056 3.5E-07
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0420617 3.5E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg01402665 chr16:50746924 NOD2 0.081 3.5E-07
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0420439 3.5E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg16771652 chr16:50730385 NOD2 -0.034 3.6E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.042 4.2E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg01242833 chr16:50760257 NOD2 -0.0431113 4.3E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 0.051 4.6E-07
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg26954174 chr16:50730813 NOD2 0.054 4.9E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 -0.0426097 5E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 -0.0425888 5.4E-07
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg04172533 chr16:50743027 NOD2 -2.2 5.4E-07
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Lifetime consumption discovery 5606 cg18177814 chr16:50730881 NOD2 NA 5.5E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 0.041 5.6E-07
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0413059 5.6E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 -0.0507429 5.6E-07
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0412836 5.7E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 -0.0407884 5.8E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.041 5.8E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg05823465 chr16:50744999 NOD2 -0.187336 5.8E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 0.055 5.9E-07
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.041 6E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg00641052 chr16:50753673 NOD2 -0.21964 6.2E-07
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 0.041 6.4E-07
Josephine Robertson 41361833 DNA methylation P01344 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.041 6.5E-07
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg05261686 chr16:50743296 NOD2 -0.0081 6.6E-07
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 -0.041021 6.7E-07
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.041 6.7E-07
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 0.041 6.7E-07
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg05823465 chr16:50744999 NOD2 0.012 6.8E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 -0.0496782 7E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg05261686 chr16:50743296 NOD2 -0.0083 7.3E-07
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.041 7.5E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0407894 7.7E-07
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 0.041 7.8E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.041 7.9E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg19513593 chr16:50731011 NOD2 -0.214734 8.2E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg24330955 chr16:50752131 NOD2 -0.0406829 8.3E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg01243823 chr16:50732212 NOD2 0.051 8.4E-07
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.041 8.7E-07
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.041 8.8E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg24330955 chr16:50752131 NOD2 -0.0405681 8.9E-07
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0405667 8.9E-07
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 3 14671 cg01068906 chr16:50745944 NOD2 0.044 8.9E-07
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0405171 9.1E-07
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.04 9.5E-07
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0404408 9.6E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg05146293 chr16:50733800 NOD2 0.043 9.7E-07
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0403345 1E-06
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.04 1E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.041 1.1E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.04 1.1E-06
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0400976 1.2E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg08848643 chr16:50745102 NOD2 0.038 1.2E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg08848643 chr16:50745102 NOD2 0.0052 1.2E-06
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Replication 5704 cg18177814 chr16:50730881 NOD2 NA 1.2E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg05146293 chr16:50733800 NOD2 -0.13 1.2E-06
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0400593 1.2E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.04 1.2E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.04 1.3E-06
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0399847 1.3E-06
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0399728 1.3E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg19513593 chr16:50731011 NOD2 -0.224915 1.3E-06
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0399323 1.3E-06
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.04 1.3E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16297928 chr16:50744223 NOD2 -0.0398864 1.3E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg19513593 chr16:50731011 NOD2 0.04 1.5E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg16771652 chr16:50730385 NOD2 -0.159131 1.6E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg03824868 chr16:50744353 NOD2 0.00059 1.6E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Stroke Whole blood Basic model 18023 cg08554257 chr16:50730737 NOD2 -0.021 1.6E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.04 1.6E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg11466773 chr16:50755855 NOD2 -0.0395782 1.6E-06
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0395664 1.6E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg05146293 chr16:50733800 NOD2 0.3 1.6E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.04 1.7E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg08554257 chr16:50730737 NOD2 -0.0512033 1.8E-06
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 4 14671 cg00796233 chr16:50740268 NOD2 -0.0532476 1.8E-06
Gross AM 27105112 DNA methylation HIV infection Neutrophils Neutrophils 60 cg01243823 chr16:50732212 NOD2 -0.237943 1.8E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0394055 1.8E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.039 1.8E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg06910119 chr16:50752702 NOD2 -0.208996 1.9E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg01020263 chr16:50732073 NOD2 -0.039832 1.9E-06
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg01243823 chr16:50732212 NOD2 -0.0115 1.9E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg08554257 chr16:50730737 NOD2 -0.059 1.9E-06
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.039 1.9E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg04172533 chr16:50743027 NOD2 -0.0592784 2E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg19513593 chr16:50731011 NOD2 -2.0 2E-06
Josephine Robertson 41361833 DNA methylation P01009 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.039227 2E-06
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0392256 2E-06
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg01068906 chr16:50745944 NOD2 0.039 2E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 4 14671 cg00796233 chr16:50740268 NOD2 -0.0528848 2.2E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.039 2.2E-06
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.039029 2.3E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.04 2.3E-06
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 1 14671 cg24330955 chr16:50752131 NOD2 -0.0389667 2.3E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0389666 2.3E-06
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0389545 2.4E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg10445147 chr16:50744420 NOD2 0.0014 2.4E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg16901027 chr16:50730221 NOD2 -0.029 2.4E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 4 14671 cg01402665 chr16:50746924 NOD2 0.12 2.5E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 -0.0508898 2.6E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg01068906 chr16:50745944 NOD2 -0.0387959 2.6E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0387891 2.6E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 0.039 2.7E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.039 2.7E-06
Mendelson MM 28095459 DNA methylation Body mass index Whole blood Framingham Heart Study Batch 2 1935 cg01243823 chr16:50732212 NOD2 -0.0186 2.7E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 0.04 2.8E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.039 2.8E-06
Sikdar S 31536415 DNA methylation Prenatal smoke exposure Cord blood, whole blood Inverse varience-weighted fixed-effects meta-analysis 5648 cg01020263 chr16:50732073 NOD2 0.011 2.8E-06
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts 5647 cg01020263 chr16:50732073 NOD2 0.011 2.8E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0386369 2.9E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 0.04 2.9E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0385669 3E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg19513593 chr16:50731011 NOD2 -0.21832 3.1E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg01242833 chr16:50760257 NOD2 2.2 3.1E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.038 3.1E-06
Singmann P 26500701 DNA methylation Sex Whole blood KORA F3 500 cg01243823 chr16:50732212 NOD2 NA 3.2E-06
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg18177814 chr16:50730881 NOD2 -0.239754 3.2E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.038 3.3E-06
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.038 3.3E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg03824868 chr16:50744353 NOD2 0.22 3.3E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg01402665 chr16:50746924 NOD2 -2.1 3.4E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg16771652 chr16:50730385 NOD2 -0.0510894 3.4E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0383213 3.4E-06
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 0.051 3.4E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 -0.038297 3.5E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.038 3.5E-06
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 -0.0392823 3.6E-06
Chatziioannou A 28225026 DNA methylation Current vs never smoking Whole blood - 454 cg16771652 chr16:50730385 NOD2 NA 3.7E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg24330955 chr16:50752131 NOD2 -0.0405941 3.7E-06
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg11466773 chr16:50755855 NOD2 -0.0381792 3.7E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.038 3.9E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0380572 4E-06
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 4 14671 cg01243823 chr16:50732212 NOD2 -0.0480294 4E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg18177814 chr16:50730881 NOD2 -0.088 4.1E-06
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.038009 4.1E-06
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.038 4.3E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 0.038 4.3E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg06181567 chr16:50731115 NOD2 0.0025 4.4E-06
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.038 4.5E-06
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0377817 4.7E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg10445147 chr16:50744420 NOD2 0.00042 4.8E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg16901027 chr16:50730221 NOD2 0.046 4.9E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg19513593 chr16:50731011 NOD2 -0.199405 4.9E-06
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 -0.0376973 4.9E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg05146293 chr16:50733800 NOD2 -0.271177 5E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg24330955 chr16:50752131 NOD2 0.04 5E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg01068906 chr16:50745944 NOD2 0.042 5E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg19513593 chr16:50731011 NOD2 0.038 5.1E-06
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 -0.037621 5.2E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Fully-adjusted model 13971 cg01243823 chr16:50732212 NOD2 -0.025 5.2E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg26954174 chr16:50730813 NOD2 -0.0073 5.2E-06
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 3 14671 cg18177814 chr16:50730881 NOD2 -0.0388496 5.2E-06
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg08848643 chr16:50745102 NOD2 0.011 5.3E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0375735 5.3E-06
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.038 5.3E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg01068906 chr16:50745944 NOD2 -0.037558 5.4E-06
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 -0.0375338 5.4E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.038 5.5E-06
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 4 14671 cg01020263 chr16:50732073 NOD2 -0.0466839 5.5E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.038 5.5E-06
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 2 14671 cg24330955 chr16:50752131 NOD2 -0.0399266 5.5E-06
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous decade consumption discovery 5606 cg18177814 chr16:50730881 NOD2 NA 5.6E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 -0.0374693 5.6E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0379278 5.9E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg24330955 chr16:50752131 NOD2 0.18 5.9E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg05146293 chr16:50733800 NOD2 0.041 5.9E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0373921 5.9E-06
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0373724 6E-06
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0373525 6E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg19513593 chr16:50731011 NOD2 0.037 6.5E-06
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg01020263 chr16:50732073 NOD2 -0.0037 6.6E-06
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg01243823 chr16:50732212 NOD2 -0.132271 6.7E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0371745 6.7E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0371363 6.8E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.037 7E-06
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.038 7.1E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 -0.0370299 7.2E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg08554257 chr16:50730737 NOD2 -0.056 7.3E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH36 whole blood OSCA model 4 14671 cg00796233 chr16:50740268 NOD2 -0.0501641 7.3E-06
Inkster A 34044884 DNA methylation Sex Placenta Discovery 585 cg26954174 chr16:50730813 NOD2 3.4 7.4E-06
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.037 7.6E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.03695 7.6E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 2 14671 cg00796233 chr16:50740268 NOD2 -0.0391093 7.6E-06
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0369151 7.7E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.037 7.8E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 0.037 7.9E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg26954174 chr16:50730813 NOD2 -0.0476557 8E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 0.037 8.1E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg08848643 chr16:50745102 NOD2 0.2 8.2E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg16771652 chr16:50730385 NOD2 0.14 8.3E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg26954174 chr16:50730813 NOD2 -0.064 8.3E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0367874 8.3E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0367229 8.6E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0367035 8.7E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg16901027 chr16:50730221 NOD2 -0.0437761 8.8E-06
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.037006 8.9E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.037 8.9E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg24330955 chr16:50752131 NOD2 0.037 9E-06
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg05146293 chr16:50733800 NOD2 -0.0405266 9.4E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 -0.0483791 9.5E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.037 9.5E-06
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.037 9.6E-06
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0365093 9.7E-06
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 -0.0375214 9.8E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg16771652 chr16:50730385 NOD2 0.049 9.9E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg01243823 chr16:50732212 NOD2 -0.033 9.9E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 -0.0364752 9.9E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.0364528 1E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0364483 1E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.036 1E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.036 1E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg08848643 chr16:50745102 NOD2 -0.19376 1E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg08374596 chr16:50744349 NOD2 0.15 1E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 0.048 1.1E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg01020263 chr16:50732073 NOD2 0.037 1.1E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg01243823 chr16:50732212 NOD2 -0.106999 1.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg16834953 chr16:50748861 NOD2 -0.049 1.1E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg16834953 chr16:50748861 NOD2 0.095 1.1E-05
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg01243823 chr16:50732212 NOD2 -0.832644 1.1E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 4 14671 cg00796233 chr16:50740268 NOD2 -0.049152 1.1E-05
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 1 14671 cg24330955 chr16:50752131 NOD2 0.036 1.1E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 2 14671 cg01402665 chr16:50746924 NOD2 -0.0698843 1.2E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg24330955 chr16:50752131 NOD2 -0.164241 1.2E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg01068906 chr16:50745944 NOD2 -0.036154 1.2E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 -0.0361423 1.2E-05
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 -0.0361389 1.2E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.036 1.2E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 3 14671 cg01402665 chr16:50746924 NOD2 -0.0696801 1.2E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.036 1.2E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg18177814 chr16:50730881 NOD2 0.037 1.3E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg04172533 chr16:50743027 NOD2 -0.0541204 1.3E-05
Gadd DA 35945220 ASPA protein levels (SeqId = 18187-16) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.92 1.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg24330955 chr16:50752131 NOD2 0.029 1.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Osteoarthritis Whole blood Basic model 16114 cg16901027 chr16:50730221 NOD2 -0.045 1.3E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0359271 1.3E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg05146293 chr16:50733800 NOD2 0.04 1.4E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg19513593 chr16:50731011 NOD2 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg02486161 chr16:50766599 NOD2 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 4 14671 cg00796233 chr16:50740268 NOD2 -0.047922 1.4E-05
Li S 28811542 DNA methylation Age Whole blood - 1366 cg26954174 chr16:50730813 NOD2 -0.00917 1.4E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.036 1.5E-05
Gadd DA 35945220 F13A1 protein levels (SeqId = 16927-9) DNA methylation Whole blood SomaScan protein measurement 774 cg01055281 chr16:50746052 NOD2 -0.81 1.5E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 -0.0468111 1.5E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 0.047 1.5E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 -0.0366089 1.6E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg16901027 chr16:50730221 NOD2 -0.058 1.6E-05
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0356107 1.6E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.036 1.6E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg08554257 chr16:50730737 NOD2 0.047 1.6E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 3 14671 cg16771652 chr16:50730385 NOD2 0.047 1.6E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg01242833 chr16:50760257 NOD2 0.19 1.6E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg01242833 chr16:50760257 NOD2 -0.20657 1.7E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 4 14671 cg00796233 chr16:50740268 NOD2 -0.0481008 1.7E-05
Chen Y 34670603 Body mass index DNA methylation Whole blood Multi-ethnic Asian meta-analysis 409 cg18177814 chr16:50730881 NOD2 -46.9 1.7E-05
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg05261686 chr16:50743296 NOD2 -1.052849 1.7E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.035 1.8E-05
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 -0.0354106 1.8E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 -0.0354065 1.8E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.036 1.8E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.035 1.8E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 4 14671 cg18177814 chr16:50730881 NOD2 0.046 1.8E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 0.035 1.9E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg01242833 chr16:50760257 NOD2 -0.0353207 1.9E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg01068906 chr16:50745944 NOD2 -0.035306 1.9E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg18177814 chr16:50730881 NOD2 0.17 1.9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg01402665 chr16:50746924 NOD2 -0.063 1.9E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg00796233 chr16:50740268 NOD2 0.037 1.9E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 -0.0355925 1.9E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.035 1.9E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 3 14671 cg18177814 chr16:50730881 NOD2 0.036 1.9E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg18177814 chr16:50730881 NOD2 -0.0354162 2E-05
Karlsson Linner R 29086770 DNA methylation Educational attainment Whole blood Basic model 10767 cg01243823 chr16:50732212 NOD2 NA 2E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 0.035 2E-05
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 3 14671 cg01020263 chr16:50732073 NOD2 -0.0358059 2E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg01055281 chr16:50746052 NOD2 -0.0059 2E-05
Gadd DA 35945220 SPINK4 protein levels (SeqId = 19213-1) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.9 2E-05
Gadd DA 35945220 NQO1 protein levels (SeqId = 9837-60) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.9 2E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 -0.0362141 2E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 0.035 2E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 4 14671 cg16771652 chr16:50730385 NOD2 -0.0673183 2.1E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg18177814 chr16:50730881 NOD2 -0.373397 2.2E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg08195491 chr16:50746063 NOD2 -0.119295 2.2E-05
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 4 14671 cg00796233 chr16:50740268 NOD2 -0.0475572 2.2E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 -0.0350287 2.2E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.035 2.2E-05
Josephine Robertson 41361833 DNA methylation P01009 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 -0.0349873 2.2E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 4 14671 cg04172533 chr16:50743027 NOD2 0.084 2.3E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg24330955 chr16:50752131 NOD2 -0.0349817 2.3E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.035 2.3E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg11466773 chr16:50755855 NOD2 0.048 2.3E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 -0.0348954 2.4E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg08554257 chr16:50730737 NOD2 -0.0458556 2.4E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 4 14671 cg16771652 chr16:50730385 NOD2 0.067 2.4E-05
Gadd DA 35945220 MZF1 protein levels (SeqId = 14662-6) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.89 2.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg01242833 chr16:50760257 NOD2 0.032 2.4E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 -0.0347968 2.5E-05
Monick MM 22232023 DNA methylation Smoking Lymphoblasts Current vs never smoking 119 cg02486161 chr16:50766599 NOD2 NA 2.5E-05
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 1 14671 cg00796233 chr16:50740268 NOD2 -0.0347636 2.5E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg08195491 chr16:50746063 NOD2 -0.0347517 2.6E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 3 14671 cg24330955 chr16:50752131 NOD2 -0.0371492 2.6E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg16771652 chr16:50730385 NOD2 -0.0463498 2.6E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 0.046 2.6E-05
Zhang L 33257653 DNA methylation alzheimers disease braak stage Prefrontal cortex Meta-analysis 1030 cg04172533 chr16:50743027 NOD2 -0.031 2.7E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Pain (Self-report) Whole blood Basic model 18413 cg24330955 chr16:50752131 NOD2 0.17 2.7E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I0 whole blood OSCA model 4 14671 cg26954174 chr16:50730813 NOD2 0.08 2.8E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg24330955 chr16:50752131 NOD2 -0.0345828 2.8E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 4 14671 cg00796233 chr16:50740268 NOD2 -0.0469429 2.8E-05
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg16771652 chr16:50730385 NOD2 -0.0093 2.9E-05
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.0348146 2.9E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.035 2.9E-05
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 -0.0355385 2.9E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg04172533 chr16:50743027 NOD2 0.052 3E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 3 14671 cg00796233 chr16:50740268 NOD2 -0.036371 3E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg04172533 chr16:50743027 NOD2 -0.0512717 3E-05
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0344524 3E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg08554257 chr16:50730737 NOD2 -0.134349 3E-05
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0349379 3.1E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 0.035 3.1E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg26954174 chr16:50730813 NOD2 -0.0444449 3.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Ischemic Heart Disease Whole blood Basic model 17483 cg24330955 chr16:50752131 NOD2 0.031 3.3E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 0.045 3.4E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg11466773 chr16:50755855 NOD2 -0.0341955 3.4E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg26954174 chr16:50730813 NOD2 -0.0341718 3.5E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg19513593 chr16:50731011 NOD2 0.034 3.5E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg01068906 chr16:50745944 NOD2 0.034 3.5E-05
Chatziioannou A 28225026 DNA methylation Current vs never smoking Whole blood - 454 cg01243823 chr16:50732212 NOD2 NA 3.5E-05
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 4 14671 cg08398764 chr16:50747670 NOD2 0.081 3.5E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg01020263 chr16:50732073 NOD2 -0.0881309 3.5E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg26954174 chr16:50730813 NOD2 -0.574212 3.6E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg04172533 chr16:50743027 NOD2 -0.0508804 3.6E-05
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood discovery 17908 cg01243823 chr16:50732212 NOD2 -0.102376 3.6E-05
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 2 14671 cg01068906 chr16:50745944 NOD2 0.037 3.6E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg00796233 chr16:50740268 NOD2 0.035 3.7E-05
Gadd DA 35945220 GZMA protein levels (SeqId = 3440-7) DNA methylation Whole blood SomaScan protein measurement 774 cg01020263 chr16:50732073 NOD2 -0.52 3.7E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.034 3.7E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 -0.0340361 3.7E-05
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg01243823 chr16:50732212 NOD2 NA 3.8E-05
Christiansen C 33593402 DNA methylation Smoking Whole blood Current vs never smoking meta-analysis in European samples 912 cg16771652 chr16:50730385 NOD2 NA 3.8E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg01402665 chr16:50746924 NOD2 -0.034 3.8E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg16901027 chr16:50730221 NOD2 -0.0414203 3.8E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg16834953 chr16:50748861 NOD2 0.034 3.8E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg00641052 chr16:50753673 NOD2 0.033 3.9E-05
Starling PS 33356526 DNA methylation maternal serum perfluorononanoate (PFNA) cord blood Discovery 583 cg01243823 chr16:50732212 NOD2 -0.0413 3.9E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 0.034 4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg05261686 chr16:50743296 NOD2 -0.02 4E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg01068906 chr16:50745944 NOD2 -0.0366104 4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Osteoarthritis Whole blood Basic model 16114 cg01243823 chr16:50732212 NOD2 -0.035 4.2E-05
Gadd DA 35945220 KLK6 protein levels (SeqId = 3450-4) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.87 4.2E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 0.034 4.3E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 -0.0417533 4.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg08848643 chr16:50745102 NOD2 -0.0058 4.3E-05
Gadd DA 35945220 RHPN2 protein levels (SeqId = 11439-88) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.87 4.3E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0337399 4.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Osteoarthritis Whole blood Basic model 16114 cg01020263 chr16:50732073 NOD2 -0.031 4.4E-05
Chen Y 34670603 Body mass index DNA methylation Whole blood Multi-ethnic Asian meta-analysis 409 cg01243823 chr16:50732212 NOD2 -22.3 4.4E-05
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg26954174 chr16:50730813 NOD2 -0.0033 4.4E-05
Gadd DA 35945220 NELL1 protein levels (SeqId = 6544-33) DNA methylation Whole blood SomaScan protein measurement 774 cg02119982 chr16:50731412 NOD2 -0.48 4.5E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg16771652 chr16:50730385 NOD2 -0.0007 4.5E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg01242833 chr16:50760257 NOD2 -0.0348696 4.5E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 -0.0436409 4.5E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg01402665 chr16:50746924 NOD2 -0.0638584 4.5E-05
Gadd DA 35945220 CST8 protein levels (SeqId = 10572-65) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.86 4.6E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.034 4.6E-05
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 0.034 4.6E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg26954174 chr16:50730813 NOD2 -0.0425396 4.7E-05
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.034 4.8E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg01402665 chr16:50746924 NOD2 -0.0634901 4.8E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 3 14671 cg18177814 chr16:50730881 NOD2 0.035 4.8E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 4 14671 cg08554257 chr16:50730737 NOD2 -0.0588622 5E-05
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 -0.0334858 5E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 3 14671 cg26954174 chr16:50730813 NOD2 -0.0439408 5.1E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg05146293 chr16:50733800 NOD2 0.033 5.1E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 2 14671 cg00796233 chr16:50740268 NOD2 0.035 5.1E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg01243823 chr16:50732212 NOD2 -0.0404819 5.1E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg08554257 chr16:50730737 NOD2 0.0054 5.1E-05
Gadd DA 35945220 C8A protein levels (SeqId = 2429-27) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.85 5.1E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg04172533 chr16:50743027 NOD2 -0.0493292 5.1E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg01242833 chr16:50760257 NOD2 0.033 5.1E-05
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 3 14671 cg01020263 chr16:50732073 NOD2 -0.0337529 5.2E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg19513593 chr16:50731011 NOD2 0.035 5.2E-05
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.033 5.3E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 4 14671 cg16834953 chr16:50748861 NOD2 0.084 5.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Liver Cirrhosis Whole blood Basic model 18325 cg26954174 chr16:50730813 NOD2 -0.0081 5.4E-05
Gadd DA 35945220 AKR7A3 protein levels (SeqId = 18173-11) DNA methylation Whole blood SomaScan protein measurement 774 cg06910119 chr16:50752702 NOD2 0.93 5.4E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg18177814 chr16:50730881 NOD2 -0.0332837 5.5E-05
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 4 14671 cg00796233 chr16:50740268 NOD2 -0.044906 5.5E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg00796233 chr16:50740268 NOD2 -0.0351894 5.6E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg01055281 chr16:50746052 NOD2 0.0012 5.6E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg18177814 chr16:50730881 NOD2 -0.0394601 5.6E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.033 5.6E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg08554257 chr16:50730737 NOD2 -0.39008 5.7E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 0.034 5.8E-05
Gadd DA 35945220 TFF1 protein levels (SeqId = 9185-15) DNA methylation Whole blood SomaScan protein measurement 774 cg04631897 chr16:50753188 NOD2 0.98 5.8E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 0.041 5.9E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg16901027 chr16:50730221 NOD2 -0.121527 5.9E-05
Gadd DA 35945220 FCER2 protein levels (SeqId = 3291-30) DNA methylation Whole blood SomaScan protein measurement 774 cg26954174 chr16:50730813 NOD2 0.54 5.9E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.033 5.9E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.033 5.9E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 0.033 6E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg08398764 chr16:50747670 NOD2 -0.0601715 6.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Lung Cancer Whole blood Basic model 18364 cg24330955 chr16:50752131 NOD2 0.014 6.1E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg08195491 chr16:50746063 NOD2 -0.112952 6.2E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg08398764 chr16:50747670 NOD2 -0.0756607 6.2E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg18177814 chr16:50730881 NOD2 -0.0340586 6.2E-05
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 3 14671 cg01068906 chr16:50745944 NOD2 0.036 6.3E-05
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.033 6.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg16901027 chr16:50730221 NOD2 -0.058 6.4E-05
Battram T None DNA methylation Head area Whole blood None 705 cg26954174 chr16:50730813 NOD2 -0.0073 6.5E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg01402665 chr16:50746924 NOD2 -0.0623183 6.5E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg01020263 chr16:50732073 NOD2 -0.0331965 6.6E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 -0.0406246 6.6E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg08848643 chr16:50745102 NOD2 -0.0329266 6.6E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg00641052 chr16:50753673 NOD2 0.033 6.9E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 -0.0333356 7E-05
Gadd DA 35945220 DLK2 protein levels (SeqId = 9359-9) DNA methylation Whole blood SomaScan protein measurement 774 cg01020263 chr16:50732073 NOD2 0.51 7E-05
Liu J 31197173 DNA methylation fasting glucose whole blood Base plus BMI 4808 cg16771652 chr16:50730385 NOD2 0.88 7E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg08554257 chr16:50730737 NOD2 -0.0429624 7E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 2 14671 cg18177814 chr16:50730881 NOD2 -0.0337256 7.1E-05
Josephine Robertson 41361833 DNA methylation P69905 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 0.033 7.1E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 2 14671 cg00796233 chr16:50740268 NOD2 -0.0347708 7.1E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg19513593 chr16:50731011 NOD2 0.18 7.3E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg02448735 chr16:50744993 NOD2 -0.176995 7.3E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg16901027 chr16:50730221 NOD2 -0.0327432 7.3E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 3 14671 cg01020263 chr16:50732073 NOD2 -0.033258 7.3E-05
Josephine Robertson 41361833 DNA methylation D6RF35 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 0.033 7.5E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0326867 7.5E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.032673 7.6E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg00641052 chr16:50753673 NOD2 0.033 7.6E-05
Gadd DA 35945220 TRIL protein levels (SeqId = 6527-1) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.84 7.6E-05
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 1 14671 cg08554257 chr16:50730737 NOD2 -0.032657 7.6E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 4 14671 cg01243823 chr16:50732212 NOD2 0.04 7.7E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 -0.0426844 7.8E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg01402665 chr16:50746924 NOD2 -0.0626195 7.9E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg08554257 chr16:50730737 NOD2 0.12 7.9E-05
Gadd DA 35945220 SULT2B1 protein levels (SeqId = 17209-27) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.83 7.9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg24330955 chr16:50752131 NOD2 0.031 8E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 0.043 8.1E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg01243823 chr16:50732212 NOD2 -0.0330888 8.1E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 3 14671 cg01020263 chr16:50732073 NOD2 -0.0330634 8.1E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 0.043 8.1E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg05261686 chr16:50743296 NOD2 -0.0325158 8.2E-05
Gadd DA 35945220 GZMA protein levels (SeqId = 3440-7) DNA methylation Whole blood SomaScan protein measurement 774 cg18177814 chr16:50730881 NOD2 -0.87 8.2E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg16771652 chr16:50730385 NOD2 -0.0432049 8.2E-05
Gadd DA 35945220 TCTN2 protein levels (SeqId = 11433-11) DNA methylation Whole blood SomaScan protein measurement 774 cg18177814 chr16:50730881 NOD2 -0.87 8.3E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg08554257 chr16:50730737 NOD2 0.043 8.4E-05
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns 5647 cg01020263 chr16:50732073 NOD2 0.009 8.4E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg05146293 chr16:50733800 NOD2 -0.0355831 8.4E-05
Gadd DA 35945220 POLH protein levels (SeqId = 10022-207) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.83 8.6E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.032 8.6E-05
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 4 14671 cg16901027 chr16:50730221 NOD2 0.046 8.6E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg04172533 chr16:50743027 NOD2 0.032 8.6E-05
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 4 14671 cg06181567 chr16:50731115 NOD2 0.04 8.7E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 2 14671 cg26954174 chr16:50730813 NOD2 -0.0424995 8.7E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Pain (Self-report) Whole blood Basic model 18413 cg01243823 chr16:50732212 NOD2 -0.1 8.8E-05
Josephine Robertson 41361833 DNA methylation D6RF35 whole blood OSCA model 2 14671 cg01243823 chr16:50732212 NOD2 0.033 8.8E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg01243823 chr16:50732212 NOD2 -0.0395901 8.8E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg24330955 chr16:50752131 NOD2 0.034 8.9E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg04172533 chr16:50743027 NOD2 0.17 9E-05
Gadd DA 35945220 ACY1 protein levels (SeqId = 3343-1) DNA methylation Whole blood SomaScan protein measurement 774 cg01243823 chr16:50732212 NOD2 -0.5 9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg16771652 chr16:50730385 NOD2 -0.039 9E-05
Battram T 28412973 DNA methylation Prostate cancer Prostate cancer tissue, benign prostate tissue EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE76938 136 cg01243823 chr16:50732212 NOD2 -0.0318 9.1E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg08398764 chr16:50747670 NOD2 0.032 9.1E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 -0.0393788 9.1E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg08195491 chr16:50746063 NOD2 -0.0322656 9.3E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg16771652 chr16:50730385 NOD2 0.032 9.3E-05
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Lifetime consumption discovery 5606 cg16771652 chr16:50730385 NOD2 NA 9.3E-05
Gadd DA 35945220 MMP20 protein levels (SeqId = 15419-15) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.83 9.3E-05
Gadd DA 35945220 HSCB protein levels (SeqId = 19316-2) DNA methylation Whole blood SomaScan protein measurement 774 cg19513593 chr16:50731011 NOD2 -0.83 9.4E-05
Montano C 27074206 DNA methylation Schizophrenia Whole blood Discovery 1334 cg04172533 chr16:50743027 NOD2 -0.005 9.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Lung Cancer Whole blood Basic model 18364 cg16901027 chr16:50730221 NOD2 -0.011 9.5E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg01243823 chr16:50732212 NOD2 -0.0322113 9.5E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg11466773 chr16:50755855 NOD2 0.036 9.6E-05
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 2 14671 cg16771652 chr16:50730385 NOD2 -0.0429911 9.7E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 0.032 9.7E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg01020263 chr16:50732073 NOD2 -0.0321468 9.8E-05
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 1 14671 cg01402665 chr16:50746924 NOD2 -0.0321335 9.9E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 2 14671 cg16901027 chr16:50730221 NOD2 0.04 9.9E-05

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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