EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for PHGDH

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg04857033 chr1:120258412 PHGDH 0.0022 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg07090813 chr1:120254330 PHGDH -0.0019 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg10827253 chr1:120253477 PHGDH -0.0022 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg14476101 chr1:120255992 PHGDH 0.0046 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg14476101 chr1:120255992 PHGDH -0.02 0E+00
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg14476101 chr1:120255992 PHGDH 0.022 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg16246545 chr1:120255941 PHGDH 0.0035 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg16246545 chr1:120255941 PHGDH -0.015 0E+00
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg16246545 chr1:120255941 PHGDH 0.018 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg18941831 chr1:120272766 PHGDH -0.0032 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg26791905 chr1:120254664 PHGDH -0.0031 0E+00
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg06763568 chr1:120284868 PHGDH 0.53 6.3E-143
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg04086443 chr1:120286814 PHGDH 0.14 2.1E-137
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg22389654 chr1:120273819 PHGDH 0.51 5.4E-135
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg18941831 chr1:120272766 PHGDH 0.52 4.4E-129
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg10827253 chr1:120253477 PHGDH -0.35138 5.3E-123
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg07090813 chr1:120254330 PHGDH 0.2 4.7E-118
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg14476101 chr1:120255992 PHGDH 0.44 1.1E-108
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg16246545 chr1:120255941 PHGDH 0.27 6.3E-105
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg14476101 chr1:120255992 PHGDH -0.554676 6.3E-94
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg14476101 chr1:120255992 PHGDH -0.54811 1.4E-90
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg14476101 chr1:120255992 PHGDH -0.52676 2.5E-84
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg14476101 chr1:120255992 PHGDH NA 4.6E-83
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg16246545 chr1:120255941 PHGDH NA 1.6E-81
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.1514 5.9E-76
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg26457483 chr1:120256112 PHGDH -0.527637 6.8E-76
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg26457483 chr1:120256112 PHGDH -0.523968 2.1E-75
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg26457483 chr1:120256112 PHGDH -3.1 4.2E-70
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg26457483 chr1:120256112 PHGDH -0.502531 7.7E-70
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg14476101 chr1:120255992 PHGDH -0.463194 1.1E-69
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg14476101 chr1:120255992 PHGDH -2.9 5E-69
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg14476101 chr1:120255992 PHGDH -0.458263 1.5E-68
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg14476101 chr1:120255992 PHGDH -0.435793 3.2E-62
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg26457483 chr1:120256112 PHGDH -0.445908 8E-59
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg10827253 chr1:120253477 PHGDH NA 2E-57
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg16246545 chr1:120255941 PHGDH -0.514991 4E-54
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.127151 6.2E-54
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.127027 7.9E-54
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg26457483 chr1:120256112 PHGDH -0.42175 4.4E-53
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg16246545 chr1:120255941 PHGDH -0.512887 5E-53
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.125658 1E-52
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg26457483 chr1:120256112 PHGDH -0.418124 4E-52
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg16246545 chr1:120255941 PHGDH -0.50572 5.8E-52
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.124426 4.5E-49
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.119974 3.6E-48
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg16246545 chr1:120255941 PHGDH -3.1 3.8E-47
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg16246545 chr1:120255941 PHGDH -0.453948 1.2E-45
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg16246545 chr1:120255941 PHGDH -0.449862 4.9E-45
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg16246545 chr1:120255941 PHGDH -0.438288 6.8E-43
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.13 3.3E-42
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.11121 1.3E-41
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.110946 2.1E-41
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.11 9.8E-41
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.109534 2.1E-40
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.12 9.8E-40
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.10848 1.2E-39
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg14476101 chr1:120255992 PHGDH NA 2.2E-39
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.110107 1.4E-38
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.11 1.4E-38
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.117679 1.8E-37
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.102037 2.9E-35
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.101922 3.5E-35
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.101775 4.4E-35
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg06763568 chr1:120284868 PHGDH 1.6 1.1E-34
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.101019 1.4E-34
Richard MA 29198723 DNA methylation Systolic Blood Pressure Whole blood, CD4+ T cells Meta-analysis 17010 cg14476101 chr1:120255992 PHGDH -0.0003 2.7E-34
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous decade consumption discovery 5606 cg14476101 chr1:120255992 PHGDH NA 6.2E-34
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.1 9.9E-34
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.1 1.3E-33
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.099 1.4E-33
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0992077 1.8E-33
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.098 6.5E-33
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.097 4.4E-32
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0960725 2E-31
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0990577 5.3E-31
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0974682 1.1E-30
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0935885 6.6E-30
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Lifetime consumption discovery 5606 cg14476101 chr1:120255992 PHGDH NA 2.2E-29
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0913335 1.5E-28
Wahl S 28002404 Body mass index DNA methylation Whole blood Discovery and replication 10238 cg14476101 chr1:120255992 PHGDH NA 1.5E-28
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.093634 2.5E-28
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0893576 2.1E-27
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0891746 2.7E-27
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0993122 1.2E-26
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0983849 1.2E-26
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.087792 1.7E-26
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.088 2.3E-26
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0979421 2.6E-26
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0976693 3.5E-26
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.087 4.4E-26
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.087 8.6E-26
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0945761 1.3E-25
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0856084 2.4E-25
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0945942 4.1E-25
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0958603 5.1E-25
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0849985 6.1E-25
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.091 6.3E-25
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.095 8.5E-25
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0861493 1.2E-24
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0841599 1.8E-24
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.091 2.4E-24
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0838503 2.6E-24
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0835435 3.8E-24
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0834858 4.1E-24
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.091 4.8E-24
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.083 6.2E-24
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.093 6.2E-24
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH 0.083 7.6E-24
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0830428 8.3E-24
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.082556 1.3E-23
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0823823 1.6E-23
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.087 2E-23
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.082 2.6E-23
Petersen A-K 24014485 M32197_3-4-hydroxyphenyllactate DNA methylation Whole blood no snps model 1760 cg14476101 chr1:120255992 PHGDH 3.8 2.6E-23
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0915412 3.1E-23
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg16246545 chr1:120255941 PHGDH NA 3.8E-23
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0914673 4E-23
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0815316 4.6E-23
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0815057 4.7E-23
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0971396 6.7E-23
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0854072 7E-23
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.0807325 1.2E-22
Richard MA 29198723 DNA methylation Systolic Blood Pressure Whole blood, CD4+ T cells Meta-analysis 17010 cg16246545 chr1:120255941 PHGDH -0.0002 1.2E-22
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.083 1.9E-22
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0830239 2.6E-22
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.08 3E-22
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0799262 3.1E-22
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0795808 4.7E-22
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0816874 6.6E-22
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.079 6.9E-22
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.079 7.1E-22
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.079 7.3E-22
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0791575 7.8E-22
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.079 8.5E-22
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.083 8.8E-22
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.091 1.2E-21
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.081 2E-21
Richard MA 29198723 DNA methylation Diastolic Blood Pressure Whole blood, CD4+ T cells Meta-analysis 17010 cg14476101 chr1:120255992 PHGDH -0.0004 2.1E-21
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.078 3.2E-21
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.079 5.6E-21
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.077 6.1E-21
Petersen A-K 24014485 M37202_4-androsten-3betacomma17beta-diol_disulfate_1* DNA methylation Whole blood snps as covariates model 1760 cg14476101 chr1:120255992 PHGDH -0.93 6.5E-21
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.077 1.4E-20
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0766939 1.4E-20
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.088 1.8E-20
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.076 1.9E-20
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg14476101 chr1:120255992 PHGDH -0.250214 3.1E-20
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0749892 4.7E-20
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0752499 7.1E-20
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0847926 7.4E-20
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.077 8.3E-20
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0778616 9.3E-20
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0748877 1.1E-19
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0748081 1.2E-19
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0769336 1.2E-19
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.074532 1.6E-19
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0749264 1.8E-19
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.074313 2E-19
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Lifetime consumption discovery 5606 cg16246545 chr1:120255941 PHGDH NA 2.1E-19
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0738456 3.4E-19
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery and replication 4261 cg14476101 chr1:120255992 PHGDH -0.0165689 3.4E-19
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0758755 4E-19
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0844319 4.4E-19
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0733565 5.8E-19
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0729004 9.5E-19
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.073 1.1E-18
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0787613 1.3E-18
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.073 1.4E-18
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH 0.072 1.7E-18
Wahl S 28002404 Body mass index DNA methylation Whole blood Discovery and replication 10238 cg16246545 chr1:120255941 PHGDH NA 1.8E-18
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg14476101 chr1:120255992 PHGDH 0.23 2.2E-18
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood discovery 17908 cg14476101 chr1:120255992 PHGDH -0.227237 2.6E-18
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0806719 3.7E-18
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.083 4.5E-18
Wahl S 28002404 Body mass index DNA methylation Whole blood European ancestry discovery 2707 cg14476101 chr1:120255992 PHGDH -13.48 4.5E-18
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.072 8.9E-18
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg14476101 chr1:120255992 PHGDH -0.1 9.2E-18
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0703055 1.1E-17
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous decade consumption discovery 5606 cg16246545 chr1:120255941 PHGDH NA 1.2E-17
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0704439 1.3E-17
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0700696 1.9E-17
Wahl S 28002404 Body mass index DNA mehtylation Whole blood All ancestry discovery 5387 cg14476101 chr1:120255992 PHGDH -14.5 2.1E-17
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg14476101 chr1:120255992 PHGDH -0.046 2.1E-17
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.06773 2.1E-17
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0698432 2.5E-17
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0781083 2.5E-17
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.069538 3.4E-17
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH 0.069 3.6E-17
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0828124 3.7E-17
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg26612362 chr1:120254619 PHGDH 0.0092 4.5E-17
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0693315 4.7E-17
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.077 5.9E-17
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.076 6.2E-17
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg26457483 chr1:120256112 PHGDH -1.5 6.5E-17
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH -0.0685349 9.5E-17
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0684474 1E-16
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0702707 1.2E-16
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg06763568 chr1:120284868 PHGDH -0.19871 1.2E-16
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0701416 1.3E-16
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.076 1.6E-16
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0703808 1.9E-16
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0698325 2.1E-16
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0675073 2.7E-16
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0675035 2.7E-16
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0755133 2.8E-16
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH 0.07 4.2E-16
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.0670294 4.4E-16
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH 0.067 4.4E-16
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.075 4.5E-16
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg14476101 chr1:120255992 PHGDH -0.215438 4.9E-16
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.067 5.2E-16
Ligthart S 27955697 DNA methylation C-reactive protein Whole blood Discovery 8863 cg14476101 chr1:120255992 PHGDH -0.0068 5.3E-16
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0669457 6.6E-16
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0665814 6.9E-16
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0664891 7.5E-16
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0742511 9.3E-16
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0679397 1.2E-15
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0737538 1.4E-15
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.0702359 1.6E-15
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg26457483 chr1:120256112 PHGDH -0.227933 1.8E-15
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0656273 1.8E-15
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.065616 1.8E-15
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0675287 1.9E-15
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0731242 2.2E-15
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.065278 2.5E-15
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg14476101 chr1:120255992 PHGDH -1.4 2.6E-15
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0671381 2.7E-15
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg04857033 chr1:120258412 PHGDH -0.008 3.1E-15
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0668153 3.4E-15
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0724983 3.7E-15
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0647377 4.2E-15
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0694573 4.3E-15
Aslibekyan S 26110892 DNA methylation Body mass index CD4+ T-cells, leukocytes and whole blood Meta-analysis 5474 cg14476101 chr1:120255992 PHGDH NA 4.7E-15
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0769769 5E-15
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.064 5.4E-15
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.064 6.1E-15
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg18941831 chr1:120272766 PHGDH 0.0018 7E-15
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0766306 8E-15
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.064 8.3E-15
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0639538 8.9E-15
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0639016 9.4E-15
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.066 1.1E-14
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.064 1.2E-14
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0695691 1.2E-14
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery 2306 cg14476101 chr1:120255992 PHGDH -0.0215042 1.3E-14
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg26457483 chr1:120256112 PHGDH -0.097 1.5E-14
Petersen A-K 24014485 M32197_3-4-hydroxyphenyllactate DNA methylation Whole blood no snps model 1760 cg16246545 chr1:120255941 PHGDH 3.3 1.6E-14
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.0648769 1.7E-14
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0627997 2.7E-14
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0627185 2.9E-14
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0700339 3.1E-14
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.062 3.6E-14
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0623303 4.1E-14
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg26457483 chr1:120256112 PHGDH 0.21 4.5E-14
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg16246545 chr1:120255941 PHGDH 0.25 4.5E-14
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.07 5.1E-14
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg16246545 chr1:120255941 PHGDH -0.11 5.4E-14
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0620411 5.4E-14
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0678349 6.6E-14
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0618251 6.6E-14
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.068 6.9E-14
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0677052 7.5E-14
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH 0.064 7.6E-14
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.062 8.1E-14
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0615734 8.4E-14
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0671659 9.6E-14
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0675747 9.9E-14
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0622144 1E-13
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.061 1.2E-13
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.06851 1.2E-13
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0612832 1.3E-13
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.063 1.3E-13
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0714127 1.4E-13
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.06102 1.4E-13
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0683757 1.4E-13
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH -0.0609906 1.4E-13
Nano J 28624579 DNA methylation Gamma-glutamyl transferase Peripheral blood Meta-analysis 1450 cg14476101 chr1:120255992 PHGDH -0.017 1.8E-13
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0666971 1.9E-13
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0606107 2E-13
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.066 2.2E-13
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.06 2.5E-13
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH 0.06 2.5E-13
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0610896 2.7E-13
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg26457483 chr1:120256112 PHGDH -0.042 2.8E-13
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0602368 2.8E-13
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0600837 3.3E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg11551257 chr1:120255387 PHGDH 0.00025 3.3E-13
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.067 3.6E-13
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.06 3.6E-13
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0599482 3.7E-13
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0616273 3.7E-13
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0669092 4E-13
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0658386 4.1E-13
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg24846296 chr1:120267520 PHGDH -0.205655 4.2E-13
Wahl S 28002404 Body mass index DNA mehtylation Whole blood All ancestry discovery 5387 cg16246545 chr1:120255941 PHGDH -14.0 4.8E-13
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg18941831 chr1:120272766 PHGDH -0.287512 6.7E-13
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0591691 7.4E-13
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0591043 7.8E-13
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.059 8.1E-13
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0589485 9E-13
Wahl S 28002404 Body mass index DNA methylation Whole blood All ancestry replication 4851 cg14476101 chr1:120255992 PHGDH -8.9 9.4E-13
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.068 1.3E-12
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.066 1.3E-12
Xu K 31386212 DNA methylation Alcohol Consumption Saliva adjusted for bmi 1135 cg14476101 chr1:120255992 PHGDH NA 1.4E-12
Liu C 27843151 DNA methylation Alcohol consumption per day Whole blood European ancestry 9643 cg16246545 chr1:120255941 PHGDH -0.00060598 1.5E-12
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg14476101 chr1:120255992 PHGDH 0.0024 1.6E-12
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0582109 1.7E-12
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0587579 1.8E-12
Xu K 31386212 DNA methylation Alcohol Consumption Saliva adjusted for bmi 1135 cg16246545 chr1:120255941 PHGDH NA 1.9E-12
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0630408 1.9E-12
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH 0.059 1.9E-12
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0580382 2E-12
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.069 2E-12
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery and replication adjusted for BMI 4261 cg14476101 chr1:120255992 PHGDH -0.0135 2E-12
Wahl S 28002404 Body mass index DNA methylation Whole blood European ancestry discovery 2707 cg16246545 chr1:120255941 PHGDH -12.9 2.1E-12
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.058 2.2E-12
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg24846296 chr1:120267520 PHGDH -0.200614 2.2E-12
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.06 2.2E-12
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0594354 2.4E-12
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH 0.058 2.5E-12
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood discovery 17908 cg26457483 chr1:120256112 PHGDH -0.190805 3E-12
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg16246545 chr1:120255941 PHGDH -0.046 3E-12
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg09330888 chr1:120280870 PHGDH 0.058 3.1E-12
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0576361 3.1E-12
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0574251 3.4E-12
Petersen A-K 24014485 M32197_3-4-hydroxyphenyllactate DNA methylation Whole blood snps as covariates model 1760 cg16246545 chr1:120255941 PHGDH 3.1 3.6E-12
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.062 3.8E-12
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg16246545 chr1:120255941 PHGDH -0.231507 4.2E-12
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0570176 4.8E-12
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg05958127 chr1:120254177 PHGDH 0.043 4.9E-12
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.056916 5.2E-12
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg04857033 chr1:120258412 PHGDH 0.035 5.5E-12
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg24846296 chr1:120267520 PHGDH -0.196129 5.5E-12
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH 0.056 6.2E-12
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.065541 7.3E-12
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0565097 7.4E-12
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.056 7.5E-12
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg18941831 chr1:120272766 PHGDH 0.074 7.6E-12
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0675574 8.3E-12
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0635157 8.4E-12
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0562229 9.6E-12
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0614285 9.7E-12
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0530179 1E-11
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.058 1.1E-11
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.056 1.1E-11
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0667201 1.2E-11
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.063 1.2E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg09330888 chr1:120280870 PHGDH -0.0557399 1.4E-11
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0619949 2.1E-11
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0552763 2.1E-11
Nano J 28624579 DNA methylation Gamma-glutamyl transferase Peripheral blood Meta-analysis 1450 cg16246545 chr1:120255941 PHGDH -0.014 2.2E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0614564 2.3E-11
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg26457483 chr1:120256112 PHGDH -0.186773 2.6E-11
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0565651 2.9E-11
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0657489 2.9E-11
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH 0.055 2.9E-11
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0569362 2.9E-11
Xu K 31386212 DNA methylation Alcohol Consumption Saliva not adjusted for bmi 1135 cg14476101 chr1:120255992 PHGDH NA 3.2E-11
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.061 3.2E-11
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg18941831 chr1:120272766 PHGDH -0.263826 3.3E-11
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0564518 4.3E-11
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0544552 4.5E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH -0.0543365 4.5E-11
Xu K 31386212 DNA methylation Alcohol Consumption Saliva not adjusted for bmi 1135 cg16246545 chr1:120255941 PHGDH NA 4.9E-11
Mendelson MM 28095459 DNA methylation Body mass index Whole blood Meta-analysis 3743 cg14476101 chr1:120255992 PHGDH NA 5E-11
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH 0.053 5.1E-11
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.054 5.3E-11
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0541216 5.4E-11
Wilson LE 30938765 DNA methylation Alcohol Consumption Whole blood replication 187 cg14476101 chr1:120255992 PHGDH NA 5.5E-11
Wahl S 28002404 Body mass index DNA methylation Whole blood European ancestry replication 4195 cg14476101 chr1:120255992 PHGDH -7.08 5.7E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.052928 5.8E-11
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.059 7E-11
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery and replication 4261 cg16246545 chr1:120255941 PHGDH -0.0099701 8E-11
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery adjusted for BMI 2306 cg14476101 chr1:120255992 PHGDH -0.0187794 9E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH -0.0534903 9E-11
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.0518859 9.1E-11
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.064 9.6E-11
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.055 1.1E-10
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0531804 1.2E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg09330888 chr1:120280870 PHGDH 0.053 1.2E-10
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg04857033 chr1:120258412 PHGDH NA 1.2E-10
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.059 1.4E-10
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg09330888 chr1:120280870 PHGDH 0.053 1.4E-10
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0529096 1.4E-10
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0532271 1.4E-10
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH 0.053 1.7E-10
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH 0.053 2E-10
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.052 2E-10
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.0524577 2E-10
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.052 2.1E-10
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg16246545 chr1:120255941 PHGDH -0.207179 2.3E-10
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.05227 2.4E-10
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0618925 2.5E-10
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg14476101 chr1:120255992 PHGDH -0.160885 2.6E-10
Cardona A 31506343 Type II diabetes DNA methylation Whole blood Discovery 1264 cg14476101 chr1:120255992 PHGDH -0.4 2.8E-10
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0520577 2.8E-10
Li S 28811542 DNA methylation Age Whole blood - 1366 cg10827253 chr1:120253477 PHGDH -0.0279 3.5E-10
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.052 3.6E-10
Liu C 27843151 DNA methylation Alcohol consumption per day Whole blood European ancestry 9643 cg14476101 chr1:120255992 PHGDH -0.00094059 3.7E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH 0.052 3.7E-10
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0516855 3.8E-10
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.052 3.9E-10
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.058 4.1E-10
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0579474 4.6E-10
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.055 4.7E-10
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0563869 5E-10
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.05 5E-10
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH 0.05 5.1E-10
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0512837 5.1E-10
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH 0.051 5.5E-10
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg18941831 chr1:120272766 PHGDH 0.067 5.7E-10
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.052 5.7E-10
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0510686 6E-10
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg18941831 chr1:120272766 PHGDH 0.24 6.2E-10
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg00426921 chr1:120254845 PHGDH 0.0061 6.6E-10
Ma J 30936141 DNA methylation Hepatic Fat Whole blood Meta-analysis model 1 3400 cg14476101 chr1:120255992 PHGDH NA 6.7E-10
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg06557491 chr1:120253576 PHGDH 0.031 7.2E-10
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.057 7.2E-10
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0508283 7.3E-10
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg18941831 chr1:120272766 PHGDH -0.227771 8.2E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg26791905 chr1:120254664 PHGDH -0.0069 8.4E-10
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0599867 9E-10
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.052831 9.3E-10
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg18941831 chr1:120272766 PHGDH -0.243843 9.7E-10
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0504124 1E-09
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.056 1E-09
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.05 1.1E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg14476101 chr1:120255992 PHGDH -0.078 1.1E-09
Richard MA 29198723 DNA methylation Diastolic Blood Pressure Whole blood, CD4+ T cells Meta-analysis 17010 cg16246545 chr1:120255941 PHGDH -0.0002 1.1E-09
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.055 1.1E-09
Ligthart S 27955697 DNA methylation C-reactive protein Whole blood Discovery 8863 cg16246545 chr1:120255941 PHGDH -0.0042 1.2E-09
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0501275 1.2E-09
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.0532386 1.4E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0498348 1.5E-09
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood discovery 17908 cg16246545 chr1:120255941 PHGDH -0.191162 1.7E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg09330888 chr1:120280870 PHGDH -0.0497119 1.7E-09
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0496518 1.8E-09
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0496488 1.8E-09
Gadd DA 35945220 PSAT1 protein levels (SeqId = 18342-2) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.78 1.8E-09
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH 0.05 1.8E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg14819459 chr1:120253398 PHGDH -0.0624526 1.8E-09
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH -0.0495969 1.8E-09
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0512073 1.9E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH 0.05 1.9E-09
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0495412 1.9E-09
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.059 2E-09
Ma J 30936141 DNA methylation Hepatic Fat Whole blood Meta-analysis model 2 3400 cg14476101 chr1:120255992 PHGDH NA 2.1E-09
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.053871 2.1E-09
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0494549 2.2E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg06557491 chr1:120253576 PHGDH 0.052 2.3E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.049 2.3E-09
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 3 14671 cg18941831 chr1:120272766 PHGDH 0.064 2.3E-09
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.049 2.3E-09
Gadd DA 35945220 SCUBE1 protein levels (SeqId = 8989-40) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.78 2.4E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.055 2.7E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.05 2.7E-09
Xu K 31386212 DNA methylation Alcohol Consumption Saliva adjusted for bmi 1135 cg26457483 chr1:120256112 PHGDH NA 2.8E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.05 2.8E-09
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.0522506 2.8E-09
Gadd DA 35945220 PSAT1 protein levels (SeqId = 18342-2) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.81 2.9E-09
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.055 3E-09
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0524417 3.2E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.049 3.3E-09
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0488182 3.3E-09
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.05 3.3E-09
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.049 3.4E-09
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH 0.049 3.4E-09
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg26457483 chr1:120256112 PHGDH -0.158028 3.4E-09
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg04857033 chr1:120258412 PHGDH -0.00048701 3.4E-09
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0579423 3.5E-09
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.048785 3.6E-09
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg18941831 chr1:120272766 PHGDH -0.218253 3.7E-09
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg24846296 chr1:120267520 PHGDH 0.057 4.3E-09
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg10827253 chr1:120253477 PHGDH -0.10167 4.4E-09
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH 0.048 4.5E-09
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.048 4.6E-09
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH 0.051 5.2E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0481965 5.2E-09
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg07411096 chr1:120253672 PHGDH 0.068 5.5E-09
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0481267 5.5E-09
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0499228 5.6E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.048 5.7E-09
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0480652 5.7E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0510849 5.8E-09
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg16246545 chr1:120255941 PHGDH 0.18 5.8E-09
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg05958127 chr1:120254177 PHGDH -0.0092 6E-09
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.0513642 6.2E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0479538 6.2E-09
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0479402 6.3E-09
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0481824 6.3E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH 0.048 6.5E-09
Liu C 27843151 DNA methylation Alcohol consumption per day CD14+ monocytes CD14+ monocytes 1251 cg14476101 chr1:120255992 PHGDH -0.000714 6.6E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0489861 6.9E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.048 6.9E-09
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0492043 7E-09
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg16246545 chr1:120255941 PHGDH -1.3 7.1E-09
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0477639 7.1E-09
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery 2306 cg16246545 chr1:120255941 PHGDH -0.0126024 7.9E-09
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.053 8.3E-09
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg06557491 chr1:120253576 PHGDH -0.0474588 8.9E-09
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg19563719 chr1:120281196 PHGDH -0.326305 1.1E-08
Nano J 28624579 DNA methylation Gamma-glutamyl transferase Peripheral blood Discovery 731 cg14476101 chr1:120255992 PHGDH -0.017 1.1E-08
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH 0.047 1.3E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0480198 1.4E-08
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH 0.047 1.4E-08
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.047 1.5E-08
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0466751 1.5E-08
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH 0.047 1.6E-08
Aslibekyan S 26110892 DNA methylation Waist circumference CD4+ T-cells Discovery GOLDN 991 cg14476101 chr1:120255992 PHGDH -0.0006 1.7E-08
Aslibekyan S 26110892 DNA methylation Body mass index Whole blood FHS 1 1935 cg14476101 chr1:120255992 PHGDH -0.02 1.7E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH 0.047 1.7E-08
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.046 1.8E-08
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0464427 1.8E-08
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.046 1.9E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg07090813 chr1:120254330 PHGDH 0.0068 1.9E-08
Mendelson MM 28095459 DNA methylation Body mass index Whole blood Framingham Heart Study Batch 2 1935 cg14476101 chr1:120255992 PHGDH -0.0232 1.9E-08
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.046 2.1E-08
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0476424 2.1E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.046 2.1E-08
Aslibekyan S 26110892 DNA methylation Waist circumference CD4+ T-cells and leukocytes Meta-analysis 3097 cg14476101 chr1:120255992 PHGDH NA 2.2E-08
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0460427 2.4E-08
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0451775 2.5E-08
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0474042 2.5E-08
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.055 2.6E-08
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0512034 2.7E-08
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0459274 2.7E-08
Xu K 31386212 DNA methylation Alcohol Consumption Saliva not adjusted for bmi 1135 cg26457483 chr1:120256112 PHGDH NA 2.7E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.0458483 2.8E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.046 2.8E-08
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0458195 2.8E-08
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.047 2.9E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0509904 3E-08
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg22389654 chr1:120273819 PHGDH 0.029 3.1E-08
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0511864 3.1E-08
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0456565 3.2E-08
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0456408 3.2E-08
Battram T None DNA methylation Ratio of omega 6 fatty acids to total fatty acids Whole blood None 671 cg14476101 chr1:120255992 PHGDH 0.072 3.3E-08
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0455364 3.4E-08
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.045 3.5E-08
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0456066 3.9E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg26457483 chr1:120256112 PHGDH -0.074 4.2E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.0451001 4.6E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH 0.045 4.6E-08
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.045 4.7E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0448674 4.7E-08
Karabegovic I 33990564 DNA methylation Coffee and tea consumption Whole blood Meta-analysis 15789 cg14476101 chr1:120255992 PHGDH 0.0011 4.7E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.046 4.7E-08
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH 0.045 4.9E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg24846296 chr1:120267520 PHGDH 0.15 5.4E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.047 5.5E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg06557491 chr1:120253576 PHGDH 0.047 5.5E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg05084811 chr1:120279236 PHGDH 0.045 5.6E-08
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0447276 5.7E-08
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.044795 5.7E-08
Battram T None DNA methylation Ratio of 18:2 linoleic acid to total fatty acids Whole blood None 671 cg14476101 chr1:120255992 PHGDH 0.067 5.7E-08
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0440094 5.7E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg18941831 chr1:120272766 PHGDH 0.19 5.9E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.05 6E-08
Aslibekyan S 26110892 DNA methylation Body mass index CD4+ T-cells Discovery GOLDN 991 cg14476101 chr1:120255992 PHGDH -0.0015 6.6E-08
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg16246545 chr1:120255941 PHGDH NA 6.7E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.045 7.1E-08
Jiantao Ma 30796027 DNA methylation hepatic fat whole blood Discovery 1496 cg14476101 chr1:120255992 PHGDH NA 7.5E-08
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 3 14671 cg07411096 chr1:120253672 PHGDH 0.063 7.6E-08
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH 0.044 7.8E-08
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0496517 7.9E-08
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0449005 8.1E-08
Gadd DA 35945220 DEFB1 protein levels (SeqId = 6629-3) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.725 9.3E-08
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0478712 9.5E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg14476101 chr1:120255992 PHGDH 0.14 9.5E-08
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH -0.0439837 9.8E-08
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.0466595 1E-07
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.05 1.1E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0437084 1.1E-07
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0437374 1.2E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg24846296 chr1:120267520 PHGDH 0.052 1.2E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.044 1.2E-07
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.044 1.2E-07
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.044 1.2E-07
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg10827253 chr1:120253477 PHGDH -0.00068981 1.3E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg06557491 chr1:120253576 PHGDH -0.0435859 1.3E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg04857033 chr1:120258412 PHGDH 0.001 1.3E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg16246545 chr1:120255941 PHGDH -0.082 1.3E-07
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0446298 1.3E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH 0.043 1.4E-07
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.043431 1.4E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0434076 1.5E-07
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0484275 1.6E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0432465 1.6E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.043 1.6E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.043 1.8E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg04086443 chr1:120286814 PHGDH 0.16 1.8E-07
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg16246545 chr1:120255941 PHGDH 0.0052 1.8E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg06557491 chr1:120253576 PHGDH 0.05 1.9E-07
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0481052 1.9E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg14819459 chr1:120253398 PHGDH -0.053842 2E-07
Battram T 27886173 DNA methylation Inflammatory bowel disease Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 240 cg07090813 chr1:120254330 PHGDH -0.0252 2E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0507599 2.1E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.048 2.1E-07
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH 0.045 2.2E-07
Battram T None DNA methylation Mean diameter for VLDL particles Whole blood None 685 cg14476101 chr1:120255992 PHGDH -0.133 2.3E-07
Gadd DA 35945220 SCUBE1 protein levels (SeqId = 8989-40) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.7 2.3E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0426535 2.4E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg04086443 chr1:120286814 PHGDH 0.00097 2.4E-07
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg07090813 chr1:120254330 PHGDH -0.01 2.4E-07
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.043 2.5E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.044 2.5E-07
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH -0.0425075 2.6E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.042 2.7E-07
Battram T None DNA methylation Ratio of polyunsaturated fatty acids to total fatty acids Whole blood None 671 cg14476101 chr1:120255992 PHGDH 0.063 2.7E-07
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Replication 1955 cg14476101 chr1:120255992 PHGDH -0.0126963 2.8E-07
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0423422 2.9E-07
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH 0.042 3E-07
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg16246545 chr1:120255941 PHGDH -0.158951 3E-07
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.044 3.1E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH 0.042 3.2E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg04857033 chr1:120258412 PHGDH -0.0654564 3.3E-07
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0433274 3.5E-07
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.044751 3.6E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Fully-adjusted model 13971 cg14476101 chr1:120255992 PHGDH -0.03 3.7E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0419103 3.8E-07
Wahl S 28002404 Body mass index DNA methylation Whole blood All ancestry replication 4851 cg16246545 chr1:120255941 PHGDH -7.5 3.9E-07
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0433182 4.1E-07
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.0446751 4.1E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg07090813 chr1:120254330 PHGDH -0.114603 4.3E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg10827253 chr1:120253477 PHGDH 0.0058 4.4E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0452229 4.5E-07
Wahl S 28002404 Body mass index DNA methylation Whole blood South Asian ancestry discovery 2680 cg14476101 chr1:120255992 PHGDH -28.59 4.7E-07
Gadd DA 35945220 STC2 protein levels (SeqId = 6231-46) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.68 4.7E-07
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.04151 4.9E-07
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0451514 5E-07
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0414582 5.1E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.041 5.3E-07
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0414914 5.3E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.041 5.4E-07
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0412822 5.6E-07
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0412709 5.7E-07
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.041 5.8E-07
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.041 5.8E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0480492 5.9E-07
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0376832 6.1E-07
Gadd DA 35945220 CFHR1 protein levels (SeqId = 15468-14) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.64 6.1E-07
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.041 6.2E-07
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg06557491 chr1:120253576 PHGDH 1.0 6.4E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH 0.041 6.8E-07
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.041 7E-07
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.0409031 7.2E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg22389654 chr1:120273819 PHGDH -0.00075 7.2E-07
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.0478167 7.4E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH 0.041 7.4E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg24846296 chr1:120267520 PHGDH -0.0480236 7.8E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH 0.041 8.2E-07
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0407326 8.5E-07
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH 0.041 8.8E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg06557491 chr1:120253576 PHGDH -0.0434224 9.2E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 4 14671 cg18941831 chr1:120272766 PHGDH -0.0618688 9.3E-07
Gadd DA 35945220 PRSS2 protein levels (SeqId = 5034-79) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.64 9.6E-07
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0403886 9.9E-07
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0406338 9.9E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg24846296 chr1:120267520 PHGDH -0.134463 1E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0444383 1E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.0403362 1E-06
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0403117 1E-06
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg03036514 chr1:120255011 PHGDH 0.0055 1.1E-06
Gadd DA 35945220 OXT protein levels (SeqId = 8356-88) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.66 1.1E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH -0.040125 1.2E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg24846296 chr1:120267520 PHGDH 0.046 1.2E-06
Wilson LE 30938765 DNA methylation Alcohol Consumption Whole blood replication 187 cg16246545 chr1:120255941 PHGDH NA 1.2E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH 0.04 1.2E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.044 1.2E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg06557491 chr1:120253576 PHGDH 0.043 1.3E-06
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.041 1.3E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.039963 1.3E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH 0.04 1.4E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg07411096 chr1:120253672 PHGDH 0.066 1.4E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.041 1.5E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg18941831 chr1:120272766 PHGDH -0.0522278 1.5E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH 0.04 1.6E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg24846296 chr1:120267520 PHGDH -0.132273 1.6E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.039 1.6E-06
Gadd DA 35945220 EFS protein levels (SeqId = 12572-236) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.65 1.7E-06
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.047 1.7E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.039 1.8E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0393631 1.8E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg07411096 chr1:120253672 PHGDH -0.168608 1.8E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg06763568 chr1:120284868 PHGDH 0.00095 1.9E-06
Battram T None DNA methylation Free cholesterol in large VLDL Whole blood None 659 cg14476101 chr1:120255992 PHGDH -9.9 1.9E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg22389654 chr1:120273819 PHGDH 0.001 1.9E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.039 1.9E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH -0.045641 1.9E-06
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0430116 1.9E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0418389 1.9E-06
Liu C 27843151 DNA methylation Alcohol consumption per day CD14+ monocytes CD14+ monocytes 1251 cg16246545 chr1:120255941 PHGDH -0.000474 2E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg11551257 chr1:120255387 PHGDH 0.0007 2E-06
Gadd DA 35945220 ADSSL1 protein levels (SeqId = 13998-26) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.646 2E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0392302 2E-06
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg18941831 chr1:120272766 PHGDH 0.052 2.2E-06
Gadd DA 35945220 DEFB1 protein levels (SeqId = 6629-3) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.619 2.2E-06
Gadd DA 35945220 PSAT1 protein levels (SeqId = 18342-2) DNA methylation Whole blood SomaScan protein measurement 774 cg16246545 chr1:120255941 PHGDH -0.73 2.2E-06
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.039 2.2E-06
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.043 2.3E-06
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.039 2.3E-06
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.044 2.3E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH 0.039 2.4E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg19563719 chr1:120281196 PHGDH -0.0440673 2.4E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0388968 2.4E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.0402534 2.5E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg18941831 chr1:120272766 PHGDH 0.051 2.6E-06
Gadd DA 35945220 DNER protein levels (SeqId = 11442-1) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.64 2.6E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0434412 2.6E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.039 2.7E-06
Battram T None DNA methylation Ratio of monounsaturated fatty acids to total fatty acids Whole blood None 669 cg14476101 chr1:120255992 PHGDH -0.057 2.7E-06
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg06557491 chr1:120253576 PHGDH -0.0386917 2.8E-06
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.041405 2.8E-06
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.038896 2.8E-06
Wahl S 28002404 Body mass index DNA methylation Whole blood European ancestry replication 4195 cg16246545 chr1:120255941 PHGDH -7.09 2.9E-06
Gomez-Alonso MDC 33413638 DNA methylation LAtoFA Whole blood Meta-analysis 5414 cg16246545 chr1:120255941 PHGDH 0.24 2.9E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg07090813 chr1:120254330 PHGDH -0.106152 3E-06
Cardona A 31506343 Type II diabetes DNA methylation Whole blood Replication in Indians 2664 cg14476101 chr1:120255992 PHGDH -0.211 3E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg18941831 chr1:120272766 PHGDH -1.3 3E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg18941831 chr1:120272766 PHGDH 0.049 3.1E-06
Gadd DA 35945220 CBLN1 protein levels (SeqId = 9313-27) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH 0.61 3.1E-06
Gadd DA 35945220 MARCO protein levels (SeqId = 9003-99) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.63 3.2E-06
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0384051 3.3E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH 0.04 3.4E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0383032 3.5E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0382983 3.5E-06
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0382956 3.5E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH 0.038 3.5E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg07090813 chr1:120254330 PHGDH 0.1 3.6E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.042 3.6E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.038 3.7E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.038 3.7E-06
Battram T None DNA methylation Triglycerides Whole blood fasting 678 cg14476101 chr1:120255992 PHGDH -0.37 3.7E-06
Battram T None DNA methylation VLDL cholesterol Whole blood fasting 678 cg14476101 chr1:120255992 PHGDH -0.82 3.8E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg10827253 chr1:120253477 PHGDH 0.005 3.9E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg06557491 chr1:120253576 PHGDH -0.0408067 4.1E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 4 14671 cg07411096 chr1:120253672 PHGDH -0.065466 4.1E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH -0.0390508 4.1E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg05084811 chr1:120279236 PHGDH 0.038 4.2E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg24846296 chr1:120267520 PHGDH -0.0445948 4.2E-06
Battram T None DNA methylation Cholesterol esters in large VLDL Whole blood None 661 cg14476101 chr1:120255992 PHGDH -9.5 4.3E-06
Battram T None DNA methylation Total cholesterol to total lipids ratio in medium HDL Whole blood None 682 cg14476101 chr1:120255992 PHGDH 0.079 4.3E-06
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.039 4.3E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH 0.038 4.3E-06
Karabegovic I 33990564 DNA methylation Coffee and tea consumption Whole blood Discovery 9612 cg14476101 chr1:120255992 PHGDH 0.0011 4.4E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH -0.0378814 4.4E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH -0.0378757 4.5E-06
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0389335 4.6E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg06557491 chr1:120253576 PHGDH -0.0406089 4.6E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg09330888 chr1:120280870 PHGDH 0.038 4.7E-06
Gadd DA 35945220 CLN5 protein levels (SeqId = 8874-53) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.62 4.7E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg18941831 chr1:120272766 PHGDH 0.057 4.7E-06
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0425354 4.9E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH 0.038 4.9E-06
Gadd DA 35945220 ADAM30 protein levels (SeqId = 8520-8) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.62 4.9E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.038 4.9E-06
Gadd DA 35945220 ADIPOQ protein levels (SeqId = 3554-24) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH 0.6 5E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg09330888 chr1:120280870 PHGDH -0.0376557 5.1E-06
Gadd DA 35945220 OMD protein levels (SeqId = 5358-3) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH 0.62 5.1E-06
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 2 14671 cg18941831 chr1:120272766 PHGDH 0.05 5.2E-06
Gomez-Alonso MDC 33413638 DNA methylation FAw6toFA Whole blood Meta-analysis 5414 cg16246545 chr1:120255941 PHGDH 0.2 5.2E-06
Gadd DA 35945220 TNKS protein levels (SeqId = 9907-216) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.62 5.4E-06
Gadd DA 35945220 CBLN1 protein levels (SeqId = 9313-27) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH 0.62 5.5E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg07411096 chr1:120253672 PHGDH 0.053 5.6E-06
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0374843 5.6E-06
Wahl S 28002404 Body mass index DNA methylation Whole blood South Asian ancestry discovery 2680 cg16246545 chr1:120255941 PHGDH -20.56 5.7E-06
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0374299 5.8E-06
Gadd DA 35945220 ASGR1 protein levels (SeqId = 5452-71) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.62 5.8E-06
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.045 5.9E-06
Gadd DA 35945220 ADSSL1 protein levels (SeqId = 13998-26) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.592 6E-06
Gadd DA 35945220 MASP1 protein levels (SeqId = 9125-23) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.61 6E-06
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg26791905 chr1:120254664 PHGDH -1.100593 6.3E-06
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.037 6.4E-06
Gadd DA 35945220 IL36B protein levels (SeqId = 14149-9) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.61 6.4E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg09330888 chr1:120280870 PHGDH -0.138565 6.4E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.0372246 6.5E-06
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.037 6.5E-06
Nano J 28624579 DNA methylation Gamma-glutamyl transferase Peripheral blood Replication 719 cg14476101 chr1:120255992 PHGDH -0.017 6.7E-06
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg07411096 chr1:120253672 PHGDH -0.0527464 6.8E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.04 6.9E-06
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.039 7E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg26791905 chr1:120254664 PHGDH -0.0383092 7.1E-06
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0406902 7.1E-06
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.0380416 7.3E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg07411096 chr1:120253672 PHGDH -0.0525618 7.4E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg06557491 chr1:120253576 PHGDH -0.0395426 7.4E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg13345849 chr1:120254570 PHGDH 0.039 7.6E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg26457483 chr1:120256112 PHGDH 0.12 7.6E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.044 7.6E-06
Gadd DA 35945220 GSTA1 protein levels (SeqId = 17138-8) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.61 7.7E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH -0.037579 7.8E-06
Liu C 27843151 DNA methylation Alcohol consumption per day Whole blood African ancestry 2423 cg14476101 chr1:120255992 PHGDH -7.87e-05 8.1E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.037 8.2E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg03036514 chr1:120255011 PHGDH 0.14 8.3E-06
Battram T None DNA methylation Serum total triglycerides Whole blood None 676 cg14476101 chr1:120255992 PHGDH -0.33 8.4E-06
Gadd DA 35945220 ART4 protein levels (SeqId = 6576-1) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.6 8.7E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH 0.037 8.8E-06
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0366697 8.9E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.038 8.9E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH -0.0366685 8.9E-06
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0366674 8.9E-06
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.037 9.3E-06
Juvinao-Quintero DL 33622391 DNA methylation Type 2 diabetes Whole blood meta-analysis 3428 cg14476101 chr1:120255992 PHGDH -0.015 9.5E-06
Gross AM 27105112 DNA methylation HIV infection Neutrophils Neutrophils 60 cg26791905 chr1:120254664 PHGDH -0.323341 9.5E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.037 9.5E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg07411096 chr1:120253672 PHGDH 0.052 9.5E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.043 9.5E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH -0.0365437 9.5E-06
Battram T None DNA methylation Free cholesterol to total lipids ratio in IDL Whole blood None 674 cg14476101 chr1:120255992 PHGDH 0.2 9.6E-06
Gadd DA 35945220 PRSS2 protein levels (SeqId = 5034-79) DNA methylation Whole blood SomaScan protein measurement 774 cg16246545 chr1:120255941 PHGDH -0.68 9.7E-06
Gadd DA 35945220 SPACA1 protein levels (SeqId = 6228-58) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.6 9.7E-06
Battram T None DNA methylation Triglycerides in large VLDL Whole blood None 670 cg14476101 chr1:120255992 PHGDH -1.76 9.8E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH -0.0364889 9.8E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH 0.036 9.9E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg26791905 chr1:120254664 PHGDH -0.0374432 9.9E-06
Battram T None DNA methylation Free cholesterol in medium VLDL Whole blood None 675 cg14476101 chr1:120255992 PHGDH -4.9 1E-05
Battram T None DNA methylation Total cholesterol in large VLDL Whole blood None 664 cg14476101 chr1:120255992 PHGDH -4.7 1E-05
Gadd DA 35945220 RAMP1 protein levels (SeqId = 15436-40) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.6 1E-05
Gadd DA 35945220 RBP4 protein levels (SeqId = 15633-6) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.6 1E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.036 1E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg18941831 chr1:120272766 PHGDH 0.048 1E-05
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 3 14671 cg18941831 chr1:120272766 PHGDH 0.048 1.1E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH -0.0363225 1.1E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.036 1.1E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg04857033 chr1:120258412 PHGDH -0.0561137 1.1E-05
Jiantao Ma 30796027 DNA methylation hepatic fat whole blood Replication 1904 cg14476101 chr1:120255992 PHGDH NA 1.1E-05
Battram T None DNA methylation Phospholipids in small VLDL Whole blood None 683 cg14476101 chr1:120255992 PHGDH -3.4 1.1E-05
Gadd DA 35945220 SLAMF6 protein levels (SeqId = 5128-53) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.6 1.1E-05
Gadd DA 35945220 ALDH2 protein levels (SeqId = 18381-16) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.6 1.1E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH -0.0394965 1.1E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 3 14671 cg07411096 chr1:120253672 PHGDH 0.051 1.1E-05
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.041 1.2E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg18941831 chr1:120272766 PHGDH 0.053 1.2E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg06557491 chr1:120253576 PHGDH -0.0387861 1.2E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.036 1.2E-05
Battram T None DNA methylation Cholesterol esters to total lipids ratio in medium HDL Whole blood None 683 cg14476101 chr1:120255992 PHGDH 0.075 1.2E-05
Battram T None DNA methylation Glycoprotein acetyls Whole blood None 683 cg14476101 chr1:120255992 PHGDH -0.96 1.2E-05
Gadd DA 35945220 FTL protein levels (SeqId = 15324-58) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.59 1.2E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH -0.0362058 1.2E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg04086443 chr1:120286814 PHGDH -0.140728 1.2E-05
Battram T None DNA methylation Triglycerides in VLDL Whole blood None 677 cg14476101 chr1:120255992 PHGDH -0.39 1.3E-05
Gadd DA 35945220 ACY1 protein levels (SeqId = 3343-1) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.57 1.3E-05
Gadd DA 35945220 EFS protein levels (SeqId = 12572-236) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.57 1.3E-05
Battram T None DNA methylation Triglycerides in medium VLDL Whole blood None 673 cg14476101 chr1:120255992 PHGDH -1.12 1.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg18941831 chr1:120272766 PHGDH 0.0052 1.3E-05
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg09330888 chr1:120280870 PHGDH -0.0380252 1.3E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH -0.0380576 1.3E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg24846296 chr1:120267520 PHGDH 0.041 1.4E-05
Battram T None DNA methylation Triglycerides in small HDL Whole blood None 682 cg14476101 chr1:120255992 PHGDH -10.8 1.4E-05
Gadd DA 35945220 PRSS2 protein levels (SeqId = 5034-79) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.59 1.4E-05
Gadd DA 35945220 FTH1 protein levels (SeqId = 5934-1) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.59 1.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg21941299 chr1:120281896 PHGDH 0.034 1.4E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg07411096 chr1:120253672 PHGDH 0.06 1.4E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0396895 1.4E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.038 1.4E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH 0.035 1.5E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH 0.036 1.5E-05
Gadd DA 35945220 OXT protein levels (SeqId = 8356-88) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.56 1.5E-05
Cardona A 31506343 DNA methylation Type II diabetes Whole blood Replication in Europeans 2607 cg14476101 chr1:120255992 PHGDH -0.016 1.5E-05
Gadd DA 35945220 SPACA5 protein levels (SeqId = 6494-60) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.587 1.5E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH 0.036 1.5E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg07411096 chr1:120253672 PHGDH -0.138323 1.5E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH 0.04 1.5E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg07411096 chr1:120253672 PHGDH -0.0506045 1.6E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH -0.0356264 1.6E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg11551257 chr1:120255387 PHGDH 0.00098 1.6E-05
Battram T None DNA methylation Triglycerides to total lipids ratio in medium HDL Whole blood None 683 cg14476101 chr1:120255992 PHGDH -0.115 1.6E-05
Battram T None DNA methylation Concentration of large VLDL particles Whole blood None 670 cg14476101 chr1:120255992 PHGDH -62000000.0 1.6E-05
Gadd DA 35945220 STAP1 protein levels (SeqId = 12510-3) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.59 1.6E-05
Gadd DA 35945220 C2orf66 protein levels (SeqId = 5677-15) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.59 1.6E-05
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg14476101 chr1:120255992 PHGDH NA 1.7E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.042 1.7E-05
Battram T None DNA methylation Free cholesterol in small VLDL Whole blood None 683 cg14476101 chr1:120255992 PHGDH -5.0 1.7E-05
Colicino E 32697766 All cause mortality DNA methylation Whole blood basic model 12300 cg14476101 chr1:120255992 PHGDH 0.93 1.7E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg07411096 chr1:120253672 PHGDH -0.0504671 1.7E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg06557491 chr1:120253576 PHGDH -0.0379957 1.7E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH 0.035 1.8E-05
Gadd DA 35945220 SCIMP protein levels (SeqId = 10510-62) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.58 1.8E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg14819459 chr1:120253398 PHGDH 1.1 1.8E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg18941831 chr1:120272766 PHGDH 0.047 1.8E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.041 1.8E-05
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.035 1.9E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg06557491 chr1:120253576 PHGDH -0.0379178 1.9E-05
Battram T None DNA methylation Phospholipids in large VLDL Whole blood None 669 cg14476101 chr1:120255992 PHGDH -5.7 1.9E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 4 14671 cg26457483 chr1:120256112 PHGDH 0.042 1.9E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH -0.0352225 2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg26457483 chr1:120256112 PHGDH -0.058 2E-05
Gadd DA 35945220 YIPF6 protein levels (SeqId = 9984-12) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.58 2E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg24846296 chr1:120267520 PHGDH -0.0415626 2E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.038 2.1E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0351552 2.1E-05
Gadd DA 35945220 ALDOB protein levels (SeqId = 18185-118) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.55 2.1E-05
Gadd DA 35945220 ENGASE protein levels (SeqId = 16781-2) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.577 2.1E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.035 2.2E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.039 2.2E-05
Gadd DA 35945220 FTL protein levels (SeqId = 15324-58) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.55 2.2E-05
Gadd DA 35945220 FTH1 protein levels (SeqId = 5934-1) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.55 2.2E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 4 14671 cg18941831 chr1:120272766 PHGDH 0.053 2.2E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg24846296 chr1:120267520 PHGDH -0.0349665 2.3E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg03373466 chr1:120254222 PHGDH -0.107418 2.3E-05
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0349535 2.3E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 3 14671 cg09330888 chr1:120280870 PHGDH -0.0373806 2.3E-05
Battram T None DNA methylation Concentration of medium VLDL particles Whole blood None 676 cg14476101 chr1:120255992 PHGDH -20000000.0 2.3E-05
Gadd DA 35945220 RSPO4 protein levels (SeqId = 8464-31) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.58 2.3E-05
Gadd DA 35945220 SPINK14 protein levels (SeqId = 8587-21) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.57 2.3E-05
Battram T None DNA methylation Phospholipids in medium VLDL Whole blood None 676 cg14476101 chr1:120255992 PHGDH -3.0 2.4E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg18941831 chr1:120272766 PHGDH -0.006 2.4E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg24846296 chr1:120267520 PHGDH -0.78 2.4E-05
Gadd DA 35945220 VWC2L protein levels (SeqId = 7995-16) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.57 2.4E-05
Gadd DA 35945220 GDNF protein levels (SeqId = 5822-22) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.57 2.4E-05
Gadd DA 35945220 KLRK1 protein levels (SeqId = 14095-1) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.57 2.4E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 3 14671 cg04857033 chr1:120258412 PHGDH 0.054 2.4E-05
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH 0.035 2.5E-05
Battram T None DNA methylation Triglycerides in medium HDL Whole blood None 683 cg14476101 chr1:120255992 PHGDH -10.3 2.5E-05
Battram T None DNA methylation Total lipids in large VLDL Whole blood None 671 cg14476101 chr1:120255992 PHGDH -1.01 2.5E-05
Gadd DA 35945220 POTEG protein levels (SeqId = 7960-53) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.57 2.5E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0389899 2.5E-05
Battram T None DNA methylation Total lipids in medium VLDL Whole blood None 676 cg14476101 chr1:120255992 PHGDH -0.58 2.6E-05
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0392191 2.6E-05
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.038 2.7E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg07411096 chr1:120253672 PHGDH 0.049 2.7E-05
Gadd DA 35945220 RBP5 protein levels (SeqId = 19241-31) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.55 2.7E-05
Gadd DA 35945220 ZNF566 protein levels (SeqId = 12795-2) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.57 2.8E-05
Gadd DA 35945220 CRLF2 protein levels (SeqId = 13694-24) DNA methylation Whole blood SomaScan protein measurement 774 cg07874730 chr1:120281395 PHGDH 0.98 2.8E-05
Liu J 31197173 DNA methylation fasting glucose whole blood Base 4808 cg14476101 chr1:120255992 PHGDH -0.69 2.9E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg06557491 chr1:120253576 PHGDH 0.04 2.9E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH -0.0344213 3E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg04139379 chr1:120261921 PHGDH -0.0343382 3.2E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.034311 3.2E-05
Gadd DA 35945220 ASL protein levels (SeqId = 11241-8) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.56 3.3E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0342614 3.3E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH 0.037 3.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg06763568 chr1:120284868 PHGDH -0.0042 3.4E-05
Gadd DA 35945220 TMED4 protein levels (SeqId = 9319-59) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.56 3.4E-05
Gadd DA 35945220 HRSP12 protein levels (SeqId = 14636-25) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.56 3.4E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.034 3.4E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.034192 3.4E-05
Gadd DA 35945220 SULT2A1 protein levels (SeqId = 9829-91) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.56 3.5E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg09330888 chr1:120280870 PHGDH 0.034 3.6E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg04086443 chr1:120286814 PHGDH -0.133246 3.6E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 3 14671 cg18941831 chr1:120272766 PHGDH 0.045 3.7E-05
Gadd DA 35945220 CD5L protein levels (SeqId = 3293-2) DNA methylation Whole blood SomaScan protein measurement 774 cg07477090 chr1:120255318 PHGDH -0.68 3.7E-05
Gadd DA 35945220 GSTA1 protein levels (SeqId = 17138-8) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.54 3.7E-05
Gadd DA 35945220 RBP4 protein levels (SeqId = 15633-6) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.54 3.7E-05
Gadd DA 35945220 CFHR1 protein levels (SeqId = 15468-14) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.55 3.7E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.034034 3.7E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.034 3.7E-05
Gadd DA 35945220 GAGE2D protein levels (SeqId = 18273-14) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.56 3.8E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0339725 3.9E-05
Kazmi N 31230546 DNA methylation Hypertensive disorders of pregnancy Cord blood Meta analysis unadjusted model 5242 cg18941831 chr1:120272766 PHGDH 0.0067 3.9E-05
Gadd DA 35945220 SLAMF8 protein levels (SeqId = 8994-65) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.56 3.9E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg18941831 chr1:120272766 PHGDH 0.045 3.9E-05
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg18941831 chr1:120272766 PHGDH -0.000349 4E-05
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg18941831 chr1:120272766 PHGDH 0.0033 4E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg16246545 chr1:120255941 PHGDH 0.036 4E-05
Gadd DA 35945220 STOM protein levels (SeqId = 8261-51) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.556 4.1E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg26457483 chr1:120256112 PHGDH -0.0377958 4.2E-05
Gadd DA 35945220 EGLN1 protein levels (SeqId = 9901-28) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.56 4.2E-05
Gadd DA 35945220 ITPKC protein levels (SeqId = 12507-16) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.56 4.2E-05
Gadd DA 35945220 AKR7A3 protein levels (SeqId = 18173-11) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.56 4.2E-05
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.0338021 4.2E-05
Huang D 32520614 DNA methylation Systolic Blood Pressure Whole blood Discovery 4820 cg14476101 chr1:120255992 PHGDH NA 4.3E-05
Gadd DA 35945220 ADI1 protein levels (SeqId = 12457-10) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.56 4.3E-05
Gadd DA 35945220 RBP5 protein levels (SeqId = 19241-31) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.55 4.3E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.035 4.4E-05
Battram T None DNA methylation Triglycerides in small VLDL Whole blood None 680 cg14476101 chr1:120255992 PHGDH -1.52 4.4E-05
Gadd DA 35945220 ACY1 protein levels (SeqId = 3343-1) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.55 4.4E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg24846296 chr1:120267520 PHGDH 0.04 4.4E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.038 4.5E-05
Gadd DA 35945220 ADIPOQ protein levels (SeqId = 3554-24) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH 0.55 4.5E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg18941831 chr1:120272766 PHGDH 0.044 4.6E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Fully-adjusted model 13971 cg16246545 chr1:120255941 PHGDH -0.029 4.6E-05
Tan Q 34427971 DNA methylation Age Whole blood Discovery 492 cg07090813 chr1:120254330 PHGDH 0.0097 4.7E-05
Gadd DA 35945220 FCER2 protein levels (SeqId = 3291-30) DNA methylation Whole blood SomaScan protein measurement 774 cg07477090 chr1:120255318 PHGDH -0.67 4.7E-05
Gadd DA 35945220 FBP1 protein levels (SeqId = 7206-20) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.53 4.7E-05
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 2 14671 cg24846296 chr1:120267520 PHGDH -0.0397887 4.7E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.034 4.7E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg06557491 chr1:120253576 PHGDH -0.0359341 4.7E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg04086443 chr1:120286814 PHGDH 0.034 4.7E-05
Battram T None DNA methylation Monounsaturated fatty acids 16:1 18:1 Whole blood None 667 cg14476101 chr1:120255992 PHGDH -0.195 4.8E-05
Gadd DA 35945220 SCUBE1 protein levels (SeqId = 8989-40) DNA methylation Whole blood SomaScan protein measurement 774 cg16246545 chr1:120255941 PHGDH -0.63 4.8E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH -0.0335401 4.8E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg19563719 chr1:120281196 PHGDH 0.035 4.9E-05
Battram T None DNA methylation Triglycerides to total lipids ratio in small VLDL Whole blood None 681 cg14476101 chr1:120255992 PHGDH -0.029 4.9E-05
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0334741 5E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg18941831 chr1:120272766 PHGDH -0.150013 5E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg24846296 chr1:120267520 PHGDH -0.111357 5E-05
Gadd DA 35945220 ZNF843 protein levels (SeqId = 8321-27) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.55 5.1E-05
Gadd DA 35945220 ADAM10 protein levels (SeqId = 8654-13) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.55 5.1E-05
Gadd DA 35945220 GSN protein levels (SeqId = 16607-78) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH 0.55 5.1E-05
Gadd DA 35945220 POLE2 protein levels (SeqId = 11562-9) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.549 5.1E-05
Battram T None DNA methylation Concentration of small VLDL particles Whole blood None 681 cg14476101 chr1:120255992 PHGDH -14000000.0 5.3E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg06557491 chr1:120253576 PHGDH 0.033 5.4E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH 0.033 5.4E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg13345849 chr1:120254570 PHGDH 0.033 5.5E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg05084811 chr1:120279236 PHGDH 0.033 5.6E-05
Battram T None DNA methylation Free cholesterol to total lipids ratio in large VLDL Whole blood None 676 cg14476101 chr1:120255992 PHGDH -0.036 5.6E-05
Gadd DA 35945220 PDXK protein levels (SeqId = 11098-1) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.55 5.6E-05
Gadd DA 35945220 IL17D protein levels (SeqId = 4136-40) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.547 5.6E-05
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0332537 5.6E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg18941831 chr1:120272766 PHGDH -0.0437263 5.7E-05
Gadd DA 35945220 B3GALT2 protein levels (SeqId = 11638-42) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.55 5.7E-05
Gadd DA 35945220 CES1 protein levels (SeqId = 15487-164) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.55 5.7E-05
Liu C 27843151 DNA methylation Alcohol consumption per day Whole blood African ancestry 2423 cg16246545 chr1:120255941 PHGDH -5.62e-05 5.7E-05
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH -0.0332147 5.7E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH -0.0331593 5.8E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.033 5.9E-05
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.033 5.9E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg19563719 chr1:120281196 PHGDH -0.037446 5.9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg13345849 chr1:120254570 PHGDH 0.019 5.9E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg07090813 chr1:120254330 PHGDH -0.033441 5.9E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 2 14671 cg09330888 chr1:120280870 PHGDH -0.0354121 6E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg07874730 chr1:120281395 PHGDH 0.21 6E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 4 14671 cg14476101 chr1:120255992 PHGDH 0.036 6.1E-05
Gadd DA 35945220 BLNK protein levels (SeqId = 19225-11) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.54 6.1E-05
Gadd DA 35945220 JPH4 protein levels (SeqId = 9111-40) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.54 6.1E-05
Gadd DA 35945220 S100A13 protein levels (SeqId = 7223-60) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH 0.52 6.2E-05
Gadd DA 35945220 MYZAP protein levels (SeqId = 9055-81) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.544 6.2E-05
Battram T None DNA methylation Total cholesterol in medium VLDL Whole blood None 675 cg14476101 chr1:120255992 PHGDH -2.07 6.3E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg19096424 chr1:120255104 PHGDH 0.033 6.4E-05
Gadd DA 35945220 PLCG1 protein levels (SeqId = 4563-61) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.54 6.4E-05
Gadd DA 35945220 RBM23 protein levels (SeqId = 11590-5) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.54 6.4E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH 0.033 6.4E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg14476101 chr1:120255992 PHGDH 0.034 6.5E-05
Gadd DA 35945220 RRAS2 protein levels (SeqId = 12361-102) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.54 6.5E-05
Gadd DA 35945220 ADAMTS15 protein levels (SeqId = 4533-76) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.54 6.5E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.034 6.6E-05
Gadd DA 35945220 INSL6 protein levels (SeqId = 5754-76) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.54 6.7E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH -0.0329064 6.7E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg04857033 chr1:120258412 PHGDH 0.033 6.7E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH 0.033 6.7E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH 0.033 6.9E-05
Gadd DA 35945220 QPCT protein levels (SeqId = 7849-3) DNA methylation Whole blood SomaScan protein measurement 774 cg04086443 chr1:120286814 PHGDH -0.67 7E-05
Gadd DA 35945220 TLR1 protein levels (SeqId = 11149-3) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.54 7E-05
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH -0.0369094 7E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg18941831 chr1:120272766 PHGDH 0.043 7.1E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg13345849 chr1:120254570 PHGDH 0.034 7.1E-05
Gadd DA 35945220 ALKBH2 protein levels (SeqId = 18400-52) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.54 7.2E-05
Gadd DA 35945220 POTEG protein levels (SeqId = 7960-53) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.52 7.3E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg16246545 chr1:120255941 PHGDH 0.032 7.4E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH 0.033 7.8E-05
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg04857033 chr1:120258412 PHGDH 0.0031 7.8E-05
Gadd DA 35945220 POR protein levels (SeqId = 2731-29) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.54 7.8E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg22389654 chr1:120273819 PHGDH 0.033 7.9E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.032 7.9E-05
Gadd DA 35945220 SCARB2 protein levels (SeqId = 5100-53) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.53 8.3E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg16246545 chr1:120255941 PHGDH 0.033 8.3E-05
Nicolas Fragoso-Bargas 36534481 DNA methylation HOMA-IR Whole blood discovery 456 cg14476101 chr1:120255992 PHGDH -0.087628351 8.3E-05
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 1 14671 cg07411096 chr1:120253672 PHGDH 0.032 8.4E-05
Gadd DA 35945220 SPACA1 protein levels (SeqId = 6228-58) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.51 8.4E-05
Gadd DA 35945220 PC protein levels (SeqId = 13990-1) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.53 8.4E-05
Gadd DA 35945220 PSTPIP1 protein levels (SeqId = 19168-71) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.53 8.4E-05
Gadd DA 35945220 CRISP2 protein levels (SeqId = 9282-12) DNA methylation Whole blood SomaScan protein measurement 774 cg13345849 chr1:120254570 PHGDH -0.53 8.4E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg16246545 chr1:120255941 PHGDH 0.032 8.4E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 2 14671 cg13345849 chr1:120254570 PHGDH -0.0342697 8.5E-05
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 2 14671 cg14476101 chr1:120255992 PHGDH 0.033 8.6E-05
Gadd DA 35945220 IGFBP4 protein levels (SeqId = 2950-57) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.51 8.6E-05
Battram T None DNA methylation Triglycerides in HDL Whole blood None 682 cg14476101 chr1:120255992 PHGDH -3.9 8.6E-05
Gadd DA 35945220 KLB protein levels (SeqId = 19557-3) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.511 8.6E-05
Battram T None DNA methylation Cholesterol esters in chylomicrons and extremely large VLDL Whole blood None 651 cg14476101 chr1:120255992 PHGDH -94.0 8.7E-05
Gadd DA 35945220 IRF9 protein levels (SeqId = 12439-67) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.53 8.7E-05
Anna Ulrich 38184627 DNA methylation Idiopathic/heritable pulmonary arterial hypertension whole blood Discovery 1655 cg14476101 chr1:120255992 PHGDH -11.0 8.8E-05
Gadd DA 35945220 APOC3 protein levels (SeqId = 6461-54) DNA methylation Whole blood SomaScan protein measurement 774 cg14476101 chr1:120255992 PHGDH -0.51 8.8E-05
Gadd DA 35945220 MSN protein levels (SeqId = 5009-11) DNA methylation Whole blood SomaScan protein measurement 774 cg26791905 chr1:120254664 PHGDH -0.49 8.8E-05
Gadd DA 35945220 TERF1 protein levels (SeqId = 10049-112) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.533 8.8E-05
Gadd DA 35945220 FABP12 protein levels (SeqId = 18888-37) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.53 8.8E-05
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 3 14671 cg26457483 chr1:120256112 PHGDH 0.037 8.8E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg09330888 chr1:120280870 PHGDH 0.032 8.9E-05
Gadd DA 35945220 POLI protein levels (SeqId = 13536-56) DNA methylation Whole blood SomaScan protein measurement 774 cg05958127 chr1:120254177 PHGDH -0.33 9E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg11551257 chr1:120255387 PHGDH 0.0044 9.1E-05
Gadd DA 35945220 SMEK1 protein levels (SeqId = 10866-60) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.53 9.1E-05
Gadd DA 35945220 RPS6KA1 protein levels (SeqId = 12329-21) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.53 9.1E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg07411096 chr1:120253672 PHGDH -0.137427 9.2E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg06557491 chr1:120253576 PHGDH 0.034 9.2E-05
Gadd DA 35945220 PRDX4 protein levels (SeqId = 7789-182) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.531 9.2E-05
Gadd DA 35945220 B4GALT3 protein levels (SeqId = 6921-24) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.53 9.2E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg14819459 chr1:120253398 PHGDH -0.0322764 9.2E-05
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg14476101 chr1:120255992 PHGDH -0.0322723 9.2E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg19563719 chr1:120281196 PHGDH -0.0322028 9.6E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19096424 chr1:120255104 PHGDH 0.0028 9.6E-05
Gadd DA 35945220 BCAR3 protein levels (SeqId = 12634-79) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH -0.53 9.6E-05
Gadd DA 35945220 SOD3 protein levels (SeqId = 5660-51) DNA methylation Whole blood SomaScan protein measurement 774 cg26457483 chr1:120256112 PHGDH 0.53 9.6E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg03036514 chr1:120255011 PHGDH -0.122354 9.7E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0321823 9.7E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg07411096 chr1:120253672 PHGDH -0.137333 9.7E-05
Ma J 30936141 Nonalcoholic fatty liver disease DNA methylation Whole Blood, Monocytes discovery and replication 4525 cg14476101 chr1:120255992 PHGDH NA 9.8E-05
Battram T None DNA methylation Total lipids in small VLDL Whole blood None 681 cg14476101 chr1:120255992 PHGDH -0.66 9.8E-05
Ma J 30936141 DNA methylation Hepatic Fat Whole blood Meta-analysis model 3 3400 cg14476101 chr1:120255992 PHGDH NA 9.8E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg26457483 chr1:120256112 PHGDH -0.0321519 9.8E-05
Gadd DA 35945220 CFHR1 protein levels (SeqId = 15468-14) DNA methylation Whole blood SomaScan protein measurement 774 cg16246545 chr1:120255941 PHGDH -0.59 9.9E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg03036514 chr1:120255011 PHGDH -0.121849 1E-04
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg18941831 chr1:120272766 PHGDH -0.0321199 1E-04

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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