EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for PIK3IP1

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg07548257 chr22:31686466 PIK3IP1 -0.0056 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg07548257 chr22:31686466 PIK3IP1 0.022 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg07969918 chr22:31682909 PIK3IP1 -0.0038 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg07969918 chr22:31682909 PIK3IP1 0.011 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08548559 chr22:31686097 PIK3IP1 -0.013 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg08548559 chr22:31686097 PIK3IP1 0.06 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg09592804 chr22:31686691 PIK3IP1 -7.3e-05 0E+00
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg07969918 chr22:31682909 PIK3IP1 -0.4581 6.4E-146
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg12273325 chr22:31689831 PIK3IP1 0.2 6.5E-90
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg17725019 chr22:31677931 PIK3IP1 -0.16482 1.6E-70
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg07548257 chr22:31686466 PIK3IP1 NA 2.8E-54
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg08548559 chr22:31686097 PIK3IP1 -0.318735 3.2E-52
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg08548559 chr22:31686097 PIK3IP1 -0.36168 6.6E-52
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg08548559 chr22:31686097 PIK3IP1 -3.1 4.1E-48
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg08548559 chr22:31686097 PIK3IP1 -0.349958 4.4E-48
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg04445214 chr22:31688300 PIK3IP1 0.036 9.1E-47
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg08548559 chr22:31686097 PIK3IP1 -0.2989 6.7E-46
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg07548257 chr22:31686466 PIK3IP1 0.078 1.5E-44
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.105878 7.6E-38
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg12273325 chr22:31689831 PIK3IP1 NA 1.1E-35
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 3957790 (gene symbol: PIK3IP1) Whole blood Meta-analysis 4170 cg17725019 chr22:31677931 PIK3IP1 NA 8.9E-35
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.100353 3.7E-34
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg17725019 chr22:31677931 PIK3IP1 1.0 6.2E-33
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg08548559 chr22:31686097 PIK3IP1 -0.229304 8.2E-28
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg08548559 chr22:31686097 PIK3IP1 -0.260294 1.8E-27
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg17725019 chr22:31677931 PIK3IP1 0.41 1.8E-26
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0923971 9.1E-26
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg12273325 chr22:31689831 PIK3IP1 -1.48953 1.8E-25
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg12273325 chr22:31689831 PIK3IP1 0.0016 9.5E-25
Bohlin J 27717397 DNA methylation Gestational age Cord blood Ultrasound-estimated gestational age 1068 cg07969918 chr22:31682909 PIK3IP1 -0.00103638 1E-24
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0876862 2E-23
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.087335 2.1E-23
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0812702 6.3E-23
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.08367 8.5E-22
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0788474 1.1E-21
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg08548559 chr22:31686097 PIK3IP1 0.19 3.5E-21
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0770993 8.6E-21
Bohlin J 27717397 DNA methylation Gestational age Cord blood Ultrasound-estimated gestational age 1068 cg08548559 chr22:31686097 PIK3IP1 -0.00172087 1.1E-20
Xu CJ 28056824 DNA methylation Age 4 vs age 0 Whole blood and cord blood - 269 cg07969918 chr22:31682909 PIK3IP1 NA 5E-20
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0755412 5.1E-20
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0801254 7.7E-20
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0747407 1.2E-19
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.074017 2.8E-19
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0733526 5.8E-19
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.073 7E-19
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0729349 9.1E-19
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.075 1.2E-17
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0703238 1.5E-17
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg08548559 chr22:31686097 PIK3IP1 0.2 7.6E-17
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0683016 1.2E-16
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0680876 1.5E-16
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0669968 4.5E-16
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg17725019 chr22:31677931 PIK3IP1 0.32 6.1E-16
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.067 6.2E-16
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.067 6.3E-16
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.066 1.2E-15
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.066 1.2E-15
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 -0.0651051 2.9E-15
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.065 4.4E-15
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0644974 5.3E-15
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.064 6.4E-15
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.064 6.6E-15
Wahl S 28002404 Body mass index DNA methylation Whole blood Discovery and replication 10238 cg08548559 chr22:31686097 PIK3IP1 NA 8.7E-15
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.064 9.9E-15
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16148850 chr22:31689333 PIK3IP1 0.064 1.1E-14
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0634947 1.4E-14
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.063 1.6E-14
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.063 2.9E-14
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.063 3.3E-14
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0624411 3.7E-14
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg08548559 chr22:31686097 PIK3IP1 -0.032 4E-14
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.062 4E-14
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg03863464 chr22:31688391 PIK3IP1 0.00039 5E-14
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.062 6.5E-14
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.065 1.1E-13
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0611851 1.2E-13
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.061 1.3E-13
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg07969918 chr22:31682909 PIK3IP1 -0.00542 1.4E-13
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.061 1.7E-13
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0601788 3E-13
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0600535 3.3E-13
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg17725019 chr22:31677931 PIK3IP1 -0.27488 4E-13
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.06 4.1E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg03536654 chr22:31688645 PIK3IP1 -0.00064 4.4E-13
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.059267 6.8E-13
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.059 8.3E-13
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0713906 1.3E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0979325 1.8E-12
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0579627 2.1E-12
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0617383 2.3E-12
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg12273325 chr22:31689831 PIK3IP1 -0.00621 2.5E-12
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg07969918 chr22:31682909 PIK3IP1 NA 2.5E-12
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.062 2.8E-12
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.058 2.9E-12
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg12273325 chr22:31689831 PIK3IP1 -0.10056 3.3E-12
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg03536654 chr22:31688645 PIK3IP1 0.014 3.3E-12
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.057 4.8E-12
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0569779 5E-12
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.057 5.2E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0602143 5.2E-12
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.057 5.8E-12
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg08548559 chr22:31686097 PIK3IP1 -0.00473 6.1E-12
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.061 6.2E-12
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.057 6.9E-12
Bohlin J 27717397 DNA methylation Gestational age Cord blood Ultrasound-estimated gestational age 1068 cg04445214 chr22:31688300 PIK3IP1 -0.00019954 7.1E-12
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg20988728 chr22:31688502 PIK3IP1 0.009 8.7E-12
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg17725019 chr22:31677931 PIK3IP1 0.035 9.2E-12
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.056 9.7E-12
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0561412 1E-11
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg03863464 chr22:31688391 PIK3IP1 2.5 1E-11
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg12273325 chr22:31689831 PIK3IP1 0.0011 1.1E-11
Mendelson MM 28095459 DNA methylation Body mass index Whole blood Framingham Heart Study Batch 2 1935 cg08548559 chr22:31686097 PIK3IP1 -0.0278 1.3E-11
Li M 33279932 DNA methylation Schizophrenia Whole blood main 999 cg16148850 chr22:31689333 PIK3IP1 -0.02157 1.5E-11
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0554172 1.9E-11
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg08548559 chr22:31686097 PIK3IP1 -0.024 2E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0551637 2.3E-11
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.055 2.3E-11
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.055 2.3E-11
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg15434733 chr22:31683813 PIK3IP1 -0.057 2.6E-11
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.054 4E-11
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0579804 5.3E-11
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.054 6.2E-11
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg03625627 chr22:31687370 PIK3IP1 0.00032 6.5E-11
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.054 6.7E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0563481 7.6E-11
Li M 33279932 DNA methylation Schizophrenia Whole blood adjusted for cell composition 999 cg16148850 chr22:31689333 PIK3IP1 NA 1.2E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.053 1.9E-10
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0558909 2.1E-10
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 2 14671 cg04445214 chr22:31688300 PIK3IP1 -0.0543641 2.6E-10
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0590419 2.7E-10
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.052 2.7E-10
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.052 2.7E-10
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0615404 3E-10
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0556124 3E-10
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.055 3.1E-10
Zeilinger S 23691101 DNA methylation Smoking Whole blood Current vs never smoking discovery 1011 cg08548559 chr22:31686097 PIK3IP1 NA 3.3E-10
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.052 3.4E-10
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0588114 3.4E-10
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.052 3.5E-10
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0517096 3.7E-10
Christiansen C 33593402 DNA methylation Smoking Whole blood Current vs never smoking meta-analysis in trans-ethnic samples 3425 cg15434733 chr22:31683813 PIK3IP1 -0.276 4.3E-10
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.051 4.4E-10
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0548212 5E-10
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0511367 5.7E-10
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16148850 chr22:31689333 PIK3IP1 0.051 5.8E-10
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0510982 5.9E-10
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.051 6.1E-10
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg03625627 chr22:31687370 PIK3IP1 -0.00918 6.4E-10
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0507105 8E-10
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.051 8.3E-10
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg12311644 chr22:31687046 PIK3IP1 0.17 8.5E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0505597 8.9E-10
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.054 9.1E-10
Ligthart S 27955697 DNA methylation C-reactive protein Whole blood Discovery 8863 cg08548559 chr22:31686097 PIK3IP1 -0.0038 1E-09
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg07969918 chr22:31682909 PIK3IP1 -0.00060221 1.1E-09
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.054 1.1E-09
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 3 14671 cg04445214 chr22:31688300 PIK3IP1 -0.0520449 1.1E-09
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.050252 1.1E-09
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0502177 1.2E-09
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0501512 1.2E-09
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg07969918 chr22:31682909 PIK3IP1 -0.056883 1.2E-09
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0533352 1.5E-09
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0496809 1.7E-09
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0495737 1.9E-09
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.053002 1.9E-09
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg09592804 chr22:31686691 PIK3IP1 0.0073 2.2E-09
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.049 2.3E-09
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg17725019 chr22:31677931 PIK3IP1 1.6 2.4E-09
Demerath EW 25935004 DNA methylation Waist circumference Leukocytes Discovery 2097 cg08548559 chr22:31686097 PIK3IP1 -0.0082 2.5E-09
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0526816 2.6E-09
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 -0.056438 2.7E-09
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.049 2.7E-09
Josephine Robertson 41361833 DNA methylation A0A0B4J1V0 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.049 3E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg07548257 chr22:31686466 PIK3IP1 -0.0524448 3.1E-09
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg03536654 chr22:31688645 PIK3IP1 0.014 3.2E-09
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg15434733 chr22:31683813 PIK3IP1 0.3 3.2E-09
Wahl S 28002404 Body mass index DNA methylation Whole blood European ancestry discovery 2707 cg08548559 chr22:31686097 PIK3IP1 -9.61 3.3E-09
Wahl S 28002404 Body mass index DNA mehtylation Whole blood All ancestry discovery 5387 cg08548559 chr22:31686097 PIK3IP1 -9.0 3.4E-09
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.049 3.9E-09
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.049 4E-09
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg04445214 chr22:31688300 PIK3IP1 -0.00014791 4E-09
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0484712 4.3E-09
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.048 4.3E-09
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.052 4.4E-09
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0521264 4.5E-09
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.048 4.7E-09
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg21510025 chr22:31686689 PIK3IP1 0.0082 4.9E-09
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.048 4.9E-09
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.048 5E-09
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 -0.0481525 5.4E-09
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.048 6.3E-09
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.048 6.3E-09
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.048 6.7E-09
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0477705 7.1E-09
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0477105 7.4E-09
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.048 7.8E-09
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.051 8.1E-09
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.048 8.1E-09
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.051 8.2E-09
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0560998 8.4E-09
Mendelson MM 28095459 DNA methylation Body mass index Whole blood Meta-analysis 3743 cg08548559 chr22:31686097 PIK3IP1 NA 8.7E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg16148850 chr22:31689333 PIK3IP1 0.047 9E-09
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg07969918 chr22:31682909 PIK3IP1 -0.0061 9.2E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg07969918 chr22:31682909 PIK3IP1 -0.045 9.3E-09
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.047 9.7E-09
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.051 9.8E-09
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.047 1.1E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0470514 1.2E-08
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.047 1.2E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.047 1.3E-08
Christiansen C 33593402 DNA methylation Smoking Whole blood Current vs never smoking meta-analysis in European samples 912 cg15434733 chr22:31683813 PIK3IP1 NA 1.3E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg07548257 chr22:31686466 PIK3IP1 -0.119601 1.4E-08
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 4 14671 cg04445214 chr22:31688300 PIK3IP1 -0.054692 1.5E-08
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.05 1.5E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 -0.0467318 1.5E-08
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg08548559 chr22:31686097 PIK3IP1 -0.016 1.5E-08
Josephine Robertson 41361833 DNA methylation A0A0B4J1V0 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.047 1.6E-08
Darina Czamara 38600394 DNA methylation sex placenta meta-analysis of robust linear regression results per cohort 746 cg03065202 chr22:31687698 PIK3IP1 -0.2147907 1.8E-08
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg08548559 chr22:31686097 PIK3IP1 -1.263034 1.8E-08
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.046 1.8E-08
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.046 1.8E-08
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg17725019 chr22:31677931 PIK3IP1 0.22 1.8E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.046 1.9E-08
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0498693 1.9E-08
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0463582 1.9E-08
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0462517 2.1E-08
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg07548257 chr22:31686466 PIK3IP1 -0.117973 2.4E-08
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg03065202 chr22:31687698 PIK3IP1 0.0063 2.4E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0459757 2.5E-08
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0541421 2.8E-08
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0457459 3E-08
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.046 3E-08
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.046 3.1E-08
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.046 3.5E-08
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.045 3.9E-08
Kyung WK 32795589 DNA methylation atopy nasal polyp discovery 108 cg12273325 chr22:31689831 PIK3IP1 -0.027 4E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0452168 4.3E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg08395140 chr22:31688527 PIK3IP1 0.00018 4.4E-08
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.048 5.1E-08
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg07548257 chr22:31686466 PIK3IP1 0.045 5.3E-08
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.045 5.4E-08
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0478375 5.5E-08
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg12273325 chr22:31689831 PIK3IP1 0.17 5.7E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg07548257 chr22:31686466 PIK3IP1 0.11 5.8E-08
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg03863464 chr22:31688391 PIK3IP1 0.0081 5.9E-08
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0447292 6E-08
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.048 6.5E-08
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg08548559 chr22:31686097 PIK3IP1 -0.03742 6.6E-08
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0444934 7E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 -0.0442995 8E-08
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg08395140 chr22:31688527 PIK3IP1 0.008 8.2E-08
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.044 8.3E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg07548257 chr22:31686466 PIK3IP1 0.13 8.4E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 0.053 8.6E-08
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0501125 8.7E-08
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.044 8.8E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg07548257 chr22:31686466 PIK3IP1 -0.129578 8.9E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg17725019 chr22:31677931 PIK3IP1 -0.0558445 9.6E-08
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0439481 1E-07
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.044 1.1E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.044 1.1E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.044 1.1E-07
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg07548257 chr22:31686466 PIK3IP1 -0.129278 1.1E-07
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg08548559 chr22:31686097 PIK3IP1 -0.0059 1.2E-07
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0466277 1.2E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 -0.049231 1.3E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0469175 1.3E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg17725019 chr22:31677931 PIK3IP1 0.046 1.4E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0655335 1.5E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0612253 1.6E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg03863464 chr22:31688391 PIK3IP1 0.0012 1.6E-07
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0432093 1.6E-07
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.043 1.6E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0431707 1.7E-07
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns 5647 cg07969918 chr22:31682909 PIK3IP1 -0.008 1.7E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg12311644 chr22:31687046 PIK3IP1 0.0029 1.7E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg17725019 chr22:31677931 PIK3IP1 0.042 1.8E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 -0.0429447 2E-07
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg08548559 chr22:31686097 PIK3IP1 -1.1 2E-07
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.043 2.1E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg17725019 chr22:31677931 PIK3IP1 -0.0054 2.2E-07
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.043 2.3E-07
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 4 14671 cg15434733 chr22:31683813 PIK3IP1 0.052 2.5E-07
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0454773 2.5E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.043 2.6E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.046 2.6E-07
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.042151 3.3E-07
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.042 3.3E-07
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 0.073 3.3E-07
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0420529 3.5E-07
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 3 14671 cg07969918 chr22:31682909 PIK3IP1 -0.047295 3.5E-07
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0420054 3.6E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0509056 3.6E-07
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 2 14671 cg07548257 chr22:31686466 PIK3IP1 -0.0454344 3.7E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 2 14671 cg04445214 chr22:31688300 PIK3IP1 0.044 3.8E-07
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg12273325 chr22:31689831 PIK3IP1 0.17 3.8E-07
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.042 4E-07
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.042 4.1E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.042 4.4E-07
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 4 14671 cg16523255 chr22:31681123 PIK3IP1 0.11 4.5E-07
Wahl S 28002404 Body mass index DNA methylation Whole blood All ancestry replication 4851 cg08548559 chr22:31686097 PIK3IP1 -6.9 4.9E-07
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0414964 5E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH36 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.041 5E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg17725019 chr22:31677931 PIK3IP1 -0.043608 5.2E-07
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.041 5.2E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg17725019 chr22:31677931 PIK3IP1 0.044 5.3E-07
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0405936 5.3E-07
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.041 5.3E-07
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.044 5.4E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 3 14671 cg04445214 chr22:31688300 PIK3IP1 0.043 5.6E-07
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.041 5.6E-07
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.041 5.9E-07
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0411159 6.3E-07
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.041 6.8E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 4 14671 cg04445214 chr22:31688300 PIK3IP1 0.048 7.1E-07
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.043 7.7E-07
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 3 14671 cg07548257 chr22:31686466 PIK3IP1 -0.0441876 7.8E-07
Christiansen C 33593402 DNA methylation Smoking Whole blood Current vs never smoking meta-analysis in European samples 912 cg07969918 chr22:31682909 PIK3IP1 NA 8E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg16523255 chr22:31681123 PIK3IP1 -0.057229 8.1E-07
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0434161 8.5E-07
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.044 8.7E-07
Battram T None DNA methylation Insulin Whole blood fasting 674 cg03625627 chr22:31687370 PIK3IP1 -0.0056 9.3E-07
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.04 9.6E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0698202 9.6E-07
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.04 9.7E-07
Josephine Robertson 41361833 DNA methylation P23142 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.04 1E-06
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.04 1E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.04 1.1E-06
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 0.04 1.1E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH36 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.04 1.1E-06
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0454971 1.2E-06
Josephine Robertson 41361833 DNA methylation P04430 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.04 1.2E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0427792 1.2E-06
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg04445214 chr22:31688300 PIK3IP1 -0.194586 1.2E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 4 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0532402 1.2E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg16523255 chr22:31681123 PIK3IP1 -0.103462 1.3E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.043 1.3E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg12273325 chr22:31689831 PIK3IP1 0.16 1.3E-06
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.043 1.3E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0427109 1.3E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg07548257 chr22:31686466 PIK3IP1 -0.0419823 1.4E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.04 1.4E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0425188 1.5E-06
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts 5647 cg17725019 chr22:31677931 PIK3IP1 -0.008 1.5E-06
Sikdar S 31536415 DNA methylation Prenatal smoke exposure Cord blood, whole blood Inverse varience-weighted fixed-effects meta-analysis 5648 cg17725019 chr22:31677931 PIK3IP1 -0.0075 1.5E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 0.041 1.6E-06
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 3 14671 cg16523255 chr22:31681123 PIK3IP1 0.056 1.6E-06
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.04 1.6E-06
Marzi C 27824951 C-reactive protein DNA methylation Peripheral blood KORA F4 discovery 1741 cg08548559 chr22:31686097 PIK3IP1 -0.018 1.6E-06
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg17725019 chr22:31677931 PIK3IP1 0.0088 1.6E-06
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.04 1.6E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.042 1.6E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg07548257 chr22:31686466 PIK3IP1 -1.0 1.7E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg15434733 chr22:31683813 PIK3IP1 -0.235302 1.7E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.039471 1.7E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0439289 1.7E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0488844 1.8E-06
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.042 1.8E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0393727 1.8E-06
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg08548559 chr22:31686097 PIK3IP1 -0.114077 1.9E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg07548257 chr22:31686466 PIK3IP1 0.039 1.9E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg03536654 chr22:31688645 PIK3IP1 0.0029 1.9E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 0.068 1.9E-06
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0391682 2.1E-06
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0422335 2.1E-06
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.039 2.2E-06
Sikdar S 31536415 DNA methylation Prenatal smoke exposure Cord blood, whole blood Inverse varience-weighted fixed-effects meta-analysis 5648 cg07969918 chr22:31682909 PIK3IP1 -0.006 2.2E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0390674 2.2E-06
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts 5647 cg07969918 chr22:31682909 PIK3IP1 -0.006 2.2E-06
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 2 14671 cg16523255 chr22:31681123 PIK3IP1 0.055 2.2E-06
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.042 2.2E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0390323 2.3E-06
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 -0.042016 2.3E-06
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 1 14671 cg07548257 chr22:31686466 PIK3IP1 -0.03895 2.4E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.039 2.5E-06
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.039 2.7E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg19774699 chr22:31688639 PIK3IP1 0.039 2.8E-06
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.039 2.9E-06
Josephine Robertson 41361833 DNA methylation A0A0B4J1V0 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.039 2.9E-06
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 0.066 3E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.041 3E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0462418 3E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.039 3E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.041 3.1E-06
Zhao N 34008478 Lung cancer DNA methylation whole blood smoking score unadjusted 430 cg16523255 chr22:31681123 PIK3IP1 -0.263 3.1E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0384939 3.1E-06
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.038 3.2E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg15434733 chr22:31683813 PIK3IP1 0.24 3.2E-06
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.038 3.3E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.038 3.4E-06
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 0.048 3.5E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0396547 3.6E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0408465 3.6E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 2 14671 cg17725019 chr22:31677931 PIK3IP1 -0.040325 3.7E-06
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 0.066 3.8E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg07548257 chr22:31686466 PIK3IP1 -0.0411794 3.9E-06
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.038 3.9E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.038 3.9E-06
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 -0.0380843 3.9E-06
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.038 4.1E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.04 4.2E-06
Gadd DA 35945220 QPCT protein levels (SeqId = 7849-3) DNA methylation Whole blood SomaScan protein measurement 774 cg03625627 chr22:31687370 PIK3IP1 -1.0 4.5E-06
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.038 4.5E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0378286 4.6E-06
Zhao N 34008478 lung cancer DNA methylation whole blood None 430 cg16523255 chr22:31681123 PIK3IP1 -0.259 4.7E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0533551 4.8E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 4 14671 cg16523255 chr22:31681123 PIK3IP1 0.095 4.9E-06
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.04 4.9E-06
Josephine Robertson 41361833 DNA methylation A0A075B6I0 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.038 4.9E-06
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.038 5E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.04 5E-06
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.038 5.2E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg07548257 chr22:31686466 PIK3IP1 -0.0406917 5.2E-06
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0375396 5.4E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 3 14671 cg07969918 chr22:31682909 PIK3IP1 0.042 5.5E-06
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.04 5.5E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 4 14671 cg15434733 chr22:31683813 PIK3IP1 0.045 5.6E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.04 5.6E-06
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0374457 5.7E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 0.04 5.9E-06
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.037 5.9E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.037 5.9E-06
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 -0.037382 5.9E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg16148850 chr22:31689333 PIK3IP1 -0.0372691 6.3E-06
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 -0.037244 6.4E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0372211 6.5E-06
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 0.037 6.7E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0392856 6.7E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 0.042 6.8E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.037 6.9E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0524176 7E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 0.037 7.1E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.04 7.2E-06
Inkster A 34044884 DNA methylation Sex Placenta Discovery 585 cg03065202 chr22:31687698 PIK3IP1 3.4 7.2E-06
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg04445214 chr22:31688300 PIK3IP1 -0.161477 7.6E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.037 7.6E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg03625627 chr22:31687370 PIK3IP1 0.16 7.8E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg08548559 chr22:31686097 PIK3IP1 -0.043 7.8E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg19774699 chr22:31688639 PIK3IP1 -0.0368691 7.9E-06
Gadd DA 35945220 FAM19A3 protein levels (SeqId = 7839-99) DNA methylation Whole blood SomaScan protein measurement 774 cg20988728 chr22:31688502 PIK3IP1 -1.11 8E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg07969918 chr22:31682909 PIK3IP1 -0.041539 8E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH36 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.037 8.2E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.037 8.2E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.037 8.3E-06
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.037 8.3E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0367879 8.3E-06
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0391963 8.5E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg16148850 chr22:31689333 PIK3IP1 -0.0367413 8.5E-06
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.037 8.7E-06
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.037 8.7E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0508449 9E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.039 9E-06
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 0.042 9.3E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.037 9.3E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0365802 9.3E-06
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 0.039 9.7E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0389121 9.7E-06
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0413399 9.8E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg16148850 chr22:31689333 PIK3IP1 -0.0364981 9.8E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.036 9.9E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 2 14671 cg10642098 chr22:31689162 PIK3IP1 0.043 1E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 0.036 1E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.036 1E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 2 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0515542 1E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0363572 1.1E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.039 1.1E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.039 1.1E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0359196 1.1E-05
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.036 1.2E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.039 1.2E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.039 1.2E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.036 1.2E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0500181 1.2E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0510972 1.2E-05
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.036106 1.2E-05
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 -0.038696 1.2E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0406631 1.3E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 -0.036004 1.3E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 0.041 1.3E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 0.044 1.3E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.03593 1.3E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 0.045 1.4E-05
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0380857 1.5E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 3 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0504907 1.6E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.036 1.6E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0379239 1.6E-05
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0446222 1.6E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.036 1.6E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0355626 1.6E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.036 1.7E-05
Gadd DA 35945220 IGHM protein levels (SeqId = 3069-52) DNA methylation Whole blood SomaScan protein measurement 774 cg03625627 chr22:31687370 PIK3IP1 -0.954 1.7E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 -0.0354016 1.8E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 0.044 1.8E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0400842 1.8E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0606009 1.8E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0376705 1.9E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 3 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0499918 1.9E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 4 14671 cg16523255 chr22:31681123 PIK3IP1 0.092 2E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08395140 chr22:31688527 PIK3IP1 -0.00011 2E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 3 14671 cg16523255 chr22:31681123 PIK3IP1 0.05 2E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 4 14671 cg15434733 chr22:31683813 PIK3IP1 0.043 2E-05
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.038 2E-05
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.035 2.1E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.035 2.1E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg08548559 chr22:31686097 PIK3IP1 -0.100034 2.1E-05
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.035 2.1E-05
Hannon E 27572077 DNA methylation Schizophrenia Whole blood Phase 1 675 cg03863464 chr22:31688391 PIK3IP1 0.0053 2.2E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0349918 2.2E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg07548257 chr22:31686466 PIK3IP1 -0.0376808 2.4E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0348801 2.4E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.035 2.4E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0348365 2.4E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 0.035 2.5E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 2 14671 cg16523255 chr22:31681123 PIK3IP1 -0.049222 2.5E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0347352 2.6E-05
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 2 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0410727 2.6E-05
Josephine Robertson 41361833 DNA methylation A0A075B6J9 whole blood OSCA model 1 14671 cg03536654 chr22:31688645 PIK3IP1 0.035 2.6E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 4 14671 cg16523255 chr22:31681123 PIK3IP1 0.09 2.6E-05
Zhu X 26756918 DNA methylation Smoking Whole blood - 596 cg08548559 chr22:31686097 PIK3IP1 -0.154 2.6E-05
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.035 2.6E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0388752 2.7E-05
Gadd DA 35945220 GZMA protein levels (SeqId = 3440-7) DNA methylation Whole blood SomaScan protein measurement 774 cg12311644 chr22:31687046 PIK3IP1 -0.7 2.7E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg16523255 chr22:31681123 PIK3IP1 -0.0489313 2.7E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 4 14671 cg10642098 chr22:31689162 PIK3IP1 0.045 2.8E-05
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0432082 2.9E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.037 2.9E-05
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.037 3E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 4 14671 cg16523255 chr22:31681123 PIK3IP1 0.09 3.1E-05
Gadd DA 35945220 AGER protein levels (SeqId = 4125-52) DNA methylation Whole blood SomaScan protein measurement 774 cg03065202 chr22:31687698 PIK3IP1 -0.85 3.2E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.034 3.3E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.034 3.4E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0342206 3.4E-05
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0342125 3.4E-05
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 1 14671 cg03065202 chr22:31687698 PIK3IP1 0.034 3.4E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.034 3.5E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0341585 3.5E-05
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.036 3.5E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0341479 3.5E-05
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 0.034 3.6E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.037 3.6E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.037 3.7E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.034 3.7E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.036 3.7E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg08548559 chr22:31686097 PIK3IP1 -0.0841495 3.7E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg16148850 chr22:31689333 PIK3IP1 -0.0340512 3.7E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0583859 3.7E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 3 14671 cg07969918 chr22:31682909 PIK3IP1 0.039 3.8E-05
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.034 3.8E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg16148850 chr22:31689333 PIK3IP1 -0.0339773 3.8E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 3 14671 cg17725019 chr22:31677931 PIK3IP1 0.035 3.9E-05
Sharp GC 28603561 DNA methylation Cleft palate vs cleft lip Whole blood - 98 cg07548257 chr22:31686466 PIK3IP1 -0.05642541 3.9E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg17725019 chr22:31677931 PIK3IP1 0.035 3.9E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 0.059 3.9E-05
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0339212 4E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 0.041 4.1E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19774699 chr22:31688639 PIK3IP1 0.0078 4.1E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 0.034 4.1E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.036 4.1E-05
Gadd DA 35945220 GZMK protein levels (SeqId = 9545-156) DNA methylation Whole blood SomaScan protein measurement 774 cg03625627 chr22:31687370 PIK3IP1 -0.91 4.2E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.034 4.2E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg16523255 chr22:31681123 PIK3IP1 -0.084587 4.2E-05
Josephine Robertson 41361833 DNA methylation P04430 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.034 4.2E-05
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.036 4.3E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 0.058 4.3E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg04445214 chr22:31688300 PIK3IP1 -0.0351441 4.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg07548257 chr22:31686466 PIK3IP1 -0.039 4.5E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.036 4.6E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0336257 4.6E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg12273325 chr22:31689831 PIK3IP1 0.046 4.7E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 3 14671 cg10642098 chr22:31689162 PIK3IP1 0.04 4.8E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg07548257 chr22:31686466 PIK3IP1 -0.0335475 4.8E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.034 4.8E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 -0.033522 4.9E-05
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0380015 5E-05
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 -0.03346 5E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 1 14671 cg16523255 chr22:31681123 PIK3IP1 0.033 5.1E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg12273325 chr22:31689831 PIK3IP1 0.047 5.1E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 0.058 5.2E-05
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 0.058 5.2E-05
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 3 14671 cg12311644 chr22:31687046 PIK3IP1 -0.0343844 5.3E-05
Vallerga CL 32144264 Parkinson's disease DNA methylation Whole blood Meta analysis using MOA model from OSCA 2131 cg07969918 chr22:31682909 PIK3IP1 -1.84 5.3E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.036 5.3E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0368142 5.4E-05
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg08548559 chr22:31686097 PIK3IP1 -0.00072718 5.5E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 2 14671 cg16523255 chr22:31681123 PIK3IP1 0.047 5.5E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 0.036 5.5E-05
Chatziioannou A 28225026 DNA methylation Current vs never smoking Whole blood - 454 cg07969918 chr22:31682909 PIK3IP1 NA 5.6E-05
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 4 14671 cg16523255 chr22:31681123 PIK3IP1 0.087 5.7E-05
Battram T 26743604 DNA methylation Psoriasis Skin EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE73894 219 cg03863464 chr22:31688391 PIK3IP1 -0.0093 5.7E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 2 14671 cg12273325 chr22:31689831 PIK3IP1 0.047 5.8E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0372697 5.9E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg04445214 chr22:31688300 PIK3IP1 -0.0345537 6E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg26785471 chr22:31688377 PIK3IP1 0.033 6E-05
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0353999 6E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 2 14671 cg10642098 chr22:31689162 PIK3IP1 0.039 6.1E-05
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Any maternal smoking in pregnancy effect on newborns 6685 cg17725019 chr22:31677931 PIK3IP1 -0.006 6.1E-05
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 0.037 6.2E-05
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0353337 6.3E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg03863464 chr22:31688391 PIK3IP1 -0.00672 6.3E-05
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 4 14671 cg16523255 chr22:31681123 PIK3IP1 0.086 6.3E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 0.033 6.5E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg16523255 chr22:31681123 PIK3IP1 0.085 6.5E-05
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.033 6.6E-05
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.033 6.7E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg12273325 chr22:31689831 PIK3IP1 0.046 6.7E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 2 14671 cg08548559 chr22:31686097 PIK3IP1 0.035 6.8E-05
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0328229 7E-05
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 2 14671 cg12311644 chr22:31687046 PIK3IP1 -0.0338409 7E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0561846 7.1E-05
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg12273325 chr22:31689831 PIK3IP1 -0.0084 7.1E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 -0.034692 7.1E-05
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 -0.0327449 7.3E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.033 7.4E-05
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 0.057 7.4E-05
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 3 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0351727 7.6E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 1 14671 cg12273325 chr22:31689831 PIK3IP1 0.033 7.6E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 -0.0326271 7.7E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0337708 7.8E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg17725019 chr22:31677931 PIK3IP1 0.034 7.9E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg10642098 chr22:31689162 PIK3IP1 0.033 7.9E-05
Josephine Robertson 41361833 DNA methylation P04430 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.033 7.9E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg17725019 chr22:31677931 PIK3IP1 -0.0416509 7.9E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 4 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0395211 8E-05
Gadd DA 35945220 SPON1 protein levels (SeqId = 4297-62) DNA methylation Whole blood SomaScan protein measurement 774 cg03625627 chr22:31687370 PIK3IP1 -0.87 8.2E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg15434733 chr22:31683813 PIK3IP1 0.033 8.2E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.032 8.3E-05
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 4 14671 cg08548559 chr22:31686097 PIK3IP1 -0.0397371 8.4E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.035 8.4E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg17725019 chr22:31677931 PIK3IP1 -0.0324189 8.6E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 4 14671 cg17725019 chr22:31677931 PIK3IP1 0.042 8.7E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg07969918 chr22:31682909 PIK3IP1 -0.0536814 8.7E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg15434733 chr22:31683813 PIK3IP1 0.035 8.8E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg08395140 chr22:31688527 PIK3IP1 0.00052 8.8E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg17725019 chr22:31677931 PIK3IP1 0.034 8.8E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 -0.036675 8.9E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg04445214 chr22:31688300 PIK3IP1 -0.0322907 9.2E-05
Battram T None DNA methylation Insulin Whole blood None 683 cg03625627 chr22:31687370 PIK3IP1 -0.015 9.2E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg07969918 chr22:31682909 PIK3IP1 0.032 9.4E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 2 14671 cg07969918 chr22:31682909 PIK3IP1 0.036 9.5E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 3 14671 cg16523255 chr22:31681123 PIK3IP1 0.046 9.5E-05
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 3 14671 cg10642098 chr22:31689162 PIK3IP1 -0.0380407 9.6E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 4 14671 cg15434733 chr22:31683813 PIK3IP1 0.039 9.6E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg15434733 chr22:31683813 PIK3IP1 -0.0344783 9.6E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg04445214 chr22:31688300 PIK3IP1 0.036 9.6E-05
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 1 14671 cg08548559 chr22:31686097 PIK3IP1 0.032 9.7E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg10642098 chr22:31689162 PIK3IP1 0.038 9.8E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg07548257 chr22:31686466 PIK3IP1 -0.082057 9.9E-05
Ligthart S 27955697 DNA methylation C-reactive protein Whole blood Replication 4111 cg08548559 chr22:31686097 PIK3IP1 -0.0049 9.9E-05
Gadd DA 35945220 GZMA protein levels (SeqId = 3440-7) DNA methylation Whole blood SomaScan protein measurement 774 cg03625627 chr22:31687370 PIK3IP1 -0.86 9.9E-05

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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