Search results for SFI1
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg08305533 | chr22:32007224 | SFI1 | -0.012 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg08305533 | chr22:32007224 | SFI1 | 0.029 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg10691809 | chr22:31892045 | SFI1 | -0.00035 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg12737971 | chr22:31892148 | SFI1 | -0.00012 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg15791438 | chr22:31893238 | SFI1 | -0.004 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg15791438 | chr22:31893238 | SFI1 | 0.017 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg23702117 | chr22:31897078 | SFI1 | -0.0025 | 0E+00 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg15791438 | chr22:31893238 | SFI1 | -0.55525 | 9.3E-154 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg11435225 | chr22:32014422 | SFI1 | 0.65 | 2.1E-149 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg08305533 | chr22:32007224 | SFI1 | 0.25 | 1E-129 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg08305533 | chr22:32007224 | SFI1 | NA | 2.6E-112 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.12 | 1.4E-46 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3957938 (gene symbol: PISD) | Whole blood | Meta-analysis | 4170 | cg02404636 | chr22:31891804 | SFI1 | NA | 7.4E-43 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.11 | 4E-41 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.11 | 1.7E-39 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg08305533 | chr22:32007224 | SFI1 | 0.015 | 1.7E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.099 | 2.9E-33 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.097 | 3.1E-32 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg08226295 | chr22:31892562 | SFI1 | 0.02 | 4.5E-32 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.094 | 2.7E-30 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg00193210 | chr22:31985572 | SFI1 | 2.3 | 1.7E-27 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.084 | 2.5E-24 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg11435225 | chr22:32014422 | SFI1 | 0.0016 | 7E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.081 | 8.5E-23 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.079 | 1.4E-21 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.076626 | 1.5E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0761293 | 2.6E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.074776 | 1.2E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.074 | 1.8E-19 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.074 | 2.3E-19 |
| Kashima K | 33564054 | DNA methylation | gestational age | Cord blood | None | 110 | cg15791438 | chr22:31893238 | SFI1 | -0.0098 | 1.2E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.072 | 2.5E-18 |
| Joehanes R | 27651444 | DNA methylation | Current versus never smoking | Whole blood, CD4+ T cells or monocytes | Current vs never smoking | 9389 | cg08305533 | chr22:32007224 | SFI1 | 0.015 | 3.1E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg15791438 | chr22:31893238 | SFI1 | 0.072 | 3.6E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.07 | 1.4E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.07 | 2.8E-17 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg11956866 | chr22:31998253 | SFI1 | 0.059 | 3.8E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg15791438 | chr22:31893238 | SFI1 | 0.069 | 4.2E-17 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Replication | 5704 | cg08305533 | chr22:32007224 | SFI1 | NA | 4.5E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.069 | 8.3E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | -0.067355 | 3.2E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.067 | 3.3E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.0669593 | 4.7E-16 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg03211283 | chr22:31893096 | SFI1 | -0.03056 | 7.8E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.065 | 4.4E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.0640602 | 8.1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.064 | 1.1E-14 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg08226295 | chr22:31892562 | SFI1 | 2.7 | 2.1E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0627528 | 2.8E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | -0.0616406 | 7.9E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.061 | 9.1E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0612639 | 1.1E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.061 | 1.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0609342 | 1.5E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg03211283 | chr22:31893096 | SFI1 | -0.00061 | 2.1E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.06 | 2.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0954584 | 2.9E-13 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg14575131 | chr22:31933466 | SFI1 | -0.034 | 7.2E-13 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg02404636 | chr22:31891804 | SFI1 | -0.0165 | 1.1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0584077 | 1.4E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg04835068 | chr22:31957393 | SFI1 | 0.22 | 1.9E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | sensitivity | 18225 | cg04835068 | chr22:31957393 | SFI1 | 0.28 | 2E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.058 | 3.1E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.057 | 3.4E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.077 | 5.5E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.077 | 6.7E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg15791438 | chr22:31893238 | SFI1 | 0.056 | 1.1E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg11435225 | chr22:32014422 | SFI1 | -0.0011 | 1.3E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 2 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0771436 | 1.3E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.056 | 1.5E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.0551775 | 2.3E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0551583 | 2.3E-11 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0546773 | 3.4E-11 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg22480555 | chr22:31892067 | SFI1 | 0.0085 | 3.6E-11 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Fully-adjusted model | 14040 | cg00193210 | chr22:31985572 | SFI1 | 1.4 | 3.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | 0.055 | 3.8E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0588397 | 4.8E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg22480555 | chr22:31892067 | SFI1 | 0.00038 | 4.8E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.0541272 | 5.4E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0540469 | 5.7E-11 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.07178 | 9.6E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 3 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0736551 | 1E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg23702117 | chr22:31897078 | SFI1 | 0.0023 | 1.1E-10 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Ultrasound-estimated gestational age | 1068 | cg15791438 | chr22:31893238 | SFI1 | -0.0009865 | 1.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0529722 | 1.4E-10 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg21533369 | chr22:31892152 | SFI1 | -1.456399 | 1.5E-10 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg00184884 | chr22:31892343 | SFI1 | 0.0063 | 1.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg16311410 | chr22:31892793 | SFI1 | 0.052 | 2.7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 4 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.075 | 3.4E-10 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg08305533 | chr22:32007224 | SFI1 | 1.7 | 3.7E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0710981 | 4.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0513538 | 4.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0513269 | 5E-10 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg23510357 | chr22:31934920 | SFI1 | -0.044 | 6.9E-10 |
| Zeilinger S | 23691101 | DNA methylation | Smoking | Whole blood | Current vs never smoking discovery | 1011 | cg08305533 | chr22:32007224 | SFI1 | NA | 7.5E-10 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg13796737 | chr22:31968954 | SFI1 | 1.9 | 8.5E-10 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | sensitivity | 18270 | cg13796737 | chr22:31968954 | SFI1 | 0.39 | 9.8E-10 |
| Li M | 33279932 | DNA methylation | Schizophrenia | Whole blood | main | 999 | cg08226295 | chr22:31892562 | SFI1 | 0.0051 | 1.4E-09 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0791377 | 1.5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0498611 | 1.5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0497127 | 1.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | -0.0494234 | 2.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0491452 | 2.6E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0489766 | 2.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | 0.049 | 3.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.049 | 3.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 3 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0666615 | 4.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0481161 | 5.5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0515315 | 7.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0474909 | 8.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0754957 | 8.9E-09 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg07113062 | chr22:31943142 | SFI1 | -0.028 | 8.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0468918 | 1.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | 0.047 | 1.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0468187 | 1.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.047 | 1.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.0467726 | 1.4E-08 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg01168649 | chr22:31892074 | SFI1 | 0.0061 | 1.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg10511632 | chr22:32008959 | SFI1 | -0.0465233 | 1.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg16311410 | chr22:31892793 | SFI1 | 0.046 | 1.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0734227 | 1.9E-08 |
| Kyung WK | 32795589 | DNA methylation | atopy | nasal polyp | discovery | 108 | cg14575131 | chr22:31933466 | SFI1 | 0.024 | 2.2E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg11956866 | chr22:31998253 | SFI1 | -0.249745 | 2.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P15169 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.073 | 2.5E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | sensitivity | 18225 | cg00071692 | chr22:32006800 | SFI1 | 0.35 | 2.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 4 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.074 | 2.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.05 | 2.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0457108 | 3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0611651 | 3.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.072 | 3.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.045 | 3.6E-08 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Previous week consumption discovery | 5606 | cg08305533 | chr22:32007224 | SFI1 | NA | 3.6E-08 |
| Li M | 33279932 | DNA methylation | Schizophrenia | Whole blood | main | 999 | cg12114049 | chr22:31892114 | SFI1 | 0.0016 | 4.3E-08 |
| Kyung WK | 32795589 | DNA methylation | eosinophilia | nasal polyp | discovery | 129 | cg14575131 | chr22:31933466 | SFI1 | 0.025 | 5.4E-08 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg23510357 | chr22:31934920 | SFI1 | -1.6 | 6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.0447068 | 6.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0446799 | 6.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg21806053 | chr22:32009606 | SFI1 | 0.045 | 6.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.044 | 7E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg11956866 | chr22:31998253 | SFI1 | 0.00088 | 7.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0444461 | 7.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0443904 | 7.5E-08 |
| Spiers H | 25650246 | DNA methylation | Gestational age | Fetal brain | - | 179 | cg08305533 | chr22:32007224 | SFI1 | -0.10223 | 8.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg10511632 | chr22:32008959 | SFI1 | -0.0442575 | 8.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0441451 | 8.8E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg21806053 | chr22:32009606 | SFI1 | -0.298351 | 8.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.048 | 9.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0440154 | 9.6E-08 |
| Li M | 33279932 | DNA methylation | Schizophrenia | Whole blood | adjusted for cell composition | 999 | cg08226295 | chr22:31892562 | SFI1 | NA | 1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.059 | 1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 4 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.094 | 1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0438489 | 1.1E-07 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg12737971 | chr22:31892148 | SFI1 | -1.153639 | 1.1E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg04835068 | chr22:31957393 | SFI1 | -0.171871 | 1.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01714 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0435261 | 1.3E-07 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg14575131 | chr22:31933466 | SFI1 | -1.3 | 1.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.068 | 1.5E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg07113062 | chr22:31943142 | SFI1 | -0.14555 | 1.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0579047 | 1.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0584009 | 2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.042825 | 2.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0428033 | 2.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P15169 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.068 | 2.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0427285 | 2.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0588812 | 2.3E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg14575131 | chr22:31933466 | SFI1 | 0.14 | 2.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | 0.043 | 2.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0670094 | 3E-07 |
| Li M | 33279932 | DNA methylation | Schizophrenia | Whole blood | adjusted for cell composition | 999 | cg12114049 | chr22:31892114 | SFI1 | NA | 3.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 4 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0927021 | 3.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg15791438 | chr22:31893238 | SFI1 | 0.042 | 3.2E-07 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Ultrasound-estimated gestational age | 1068 | cg08305533 | chr22:32007224 | SFI1 | -0.00061326 | 3.2E-07 |
| Singmann P | 26500701 | DNA methylation | Sex | Whole blood | KORA F4 | 1799 | cg08305533 | chr22:32007224 | SFI1 | NA | 3.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0453528 | 3.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg15791438 | chr22:31893238 | SFI1 | -0.041922 | 3.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.042 | 4.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.057 | 4.3E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg01036541 | chr22:32009659 | SFI1 | -0.24575 | 4.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0416365 | 4.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg15791438 | chr22:31893238 | SFI1 | 0.042 | 4.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 4 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.06 | 4.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.041 | 5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.055 | 5.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01703 | whole blood | OSCA model 4 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0910236 | 5.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0412952 | 5.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.0432929 | 6.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.041 | 6.2E-07 |
| Gadd DA | 35945220 | GZMA protein levels (SeqId = 3440-7) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23510357 | chr22:31934920 | SFI1 | -1.1 | 6.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0410494 | 6.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0649989 | 7.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0442121 | 7.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0406899 | 8.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.041 | 8.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.041 | 9.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.064 | 9.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | -0.0402619 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.04 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | 0.04 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0402212 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0401296 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.040126 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg16311410 | chr22:31892793 | SFI1 | 0.04 | 1.2E-06 |
| Kazmi N | 31230546 | DNA methylation | Preeclampsia | Cord blood | Meta analysis unadjusted model | 3460 | cg15791438 | chr22:31893238 | SFI1 | 0.033 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 3 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0538407 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.04 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0398564 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0398477 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0398303 | 1.4E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg01036541 | chr22:32009659 | SFI1 | 0.24 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | -0.039437 | 1.8E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg01332634 | chr22:31974816 | SFI1 | -0.043 | 1.8E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg26207309 | chr22:31892053 | SFI1 | -0.00024 | 1.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.039317 | 1.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.042 | 1.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0392605 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0392151 | 2E-06 |
| Cecil CA | 27922636 | Substance use | DNA methylation | Cord blood | DNA methylation at birth | 244 | cg02404636 | chr22:31891804 | SFI1 | 0.29 | 2.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.0391277 | 2.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 3 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0527396 | 2.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg08941595 | chr22:31952631 | SFI1 | -0.0390856 | 2.2E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg00071692 | chr22:32006800 | SFI1 | -0.300561 | 2.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg15791438 | chr22:31893238 | SFI1 | -0.0389911 | 2.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0388463 | 2.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0388282 | 2.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | 0.039 | 2.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.053 | 2.8E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg04835068 | chr22:31957393 | SFI1 | -0.151752 | 2.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0385233 | 3E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg24112255 | chr22:32009807 | SFI1 | -0.212921 | 3.1E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg11435225 | chr22:32014422 | SFI1 | 0.0042 | 3.2E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg23510357 | chr22:31934920 | SFI1 | 0.19 | 3.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg10511632 | chr22:32008959 | SFI1 | -0.0384117 | 3.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02743 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.042 | 3.3E-06 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg26207309 | chr22:31892053 | SFI1 | 1.3 | 3.3E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg11956866 | chr22:31998253 | SFI1 | 0.0028 | 3.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 4 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0559876 | 3.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6H7 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0380893 | 3.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0597568 | 4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0380325 | 4.1E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg11409519 | chr22:32009686 | SFI1 | -0.214864 | 4.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.041 | 4.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg21806053 | chr22:32009606 | SFI1 | 0.038 | 4.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0379255 | 4.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.046 | 4.7E-06 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg14902306 | chr22:31891830 | SFI1 | -0.1361388 | 4.8E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg00746322 | chr22:32000496 | SFI1 | -0.233007 | 5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 2 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.05 | 5.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.051 | 5.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P15169 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.037 | 5.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0373986 | 5.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.04 | 5.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0591208 | 6.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.037 | 6.1E-06 |
| Gadd DA | 35945220 | GZMK protein levels (SeqId = 9545-156) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23510357 | chr22:31934920 | SFI1 | -0.99 | 6.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.04 | 6.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0371666 | 6.7E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg02404636 | chr22:31891804 | SFI1 | -0.00056 | 6.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg20441712 | chr22:32008978 | SFI1 | -0.0371375 | 6.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 3 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0402401 | 6.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0498037 | 7.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01701 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0589103 | 7.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.037 | 7.8E-06 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Liver Cirrhosis | Whole blood | Basic model | 18325 | cg00193210 | chr22:31985572 | SFI1 | 0.0099 | 7.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 3 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0483675 | 8.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.037 | 8.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg15791438 | chr22:31893238 | SFI1 | -0.0366048 | 9.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.037 | 9.5E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg00184884 | chr22:31892343 | SFI1 | 9.2e-05 | 9.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 3 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0497793 | 9.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | 0.036 | 9.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.039377 | 1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 2 | 14671 | cg25464687 | chr22:32010188 | SFI1 | -0.0373839 | 1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.03637 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 4 | 14671 | cg04835068 | chr22:31957393 | SFI1 | 0.053 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg16311410 | chr22:31892793 | SFI1 | 0.036 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 3 | 14671 | cg25464687 | chr22:32010188 | SFI1 | -0.036308 | 1.2E-05 |
| Gadd DA | 35945220 | LY9 protein levels (SeqId = 3324-51) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg14575131 | chr22:31933466 | SFI1 | -0.63 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg22480555 | chr22:31892067 | SFI1 | 0.036 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 2 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.05 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.0380327 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.057 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.036 | 1.4E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg00193210 | chr22:31985572 | SFI1 | 0.14 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0358598 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg10511632 | chr22:32008959 | SFI1 | 0.036 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01700 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0357972 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.035779 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg25464687 | chr22:32010188 | SFI1 | -0.035778 | 1.5E-05 |
| Liu C | 27843151 | DNA methylation | Alcohol consumption per day | Whole blood | European ancestry | 9643 | cg08305533 | chr22:32007224 | SFI1 | 0.0002 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.036 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.036 | 1.7E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg25218872 | chr22:31996918 | SFI1 | 0.22 | 1.7E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg00071692 | chr22:32006800 | SFI1 | -0.27484 | 1.8E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Neutrophils | Neutrophils | 60 | cg01168649 | chr22:31892074 | SFI1 | 0.14 | 1.8E-05 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg00184884 | chr22:31892343 | SFI1 | 0.0039 | 1.8E-05 |
| Mulder RH | 33450751 | DNA methylation | age*sex | Whole blood | Discovery | 2338 | cg08305533 | chr22:32007224 | SFI1 | 0.0013 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.035 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06312 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0353522 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.056 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.035 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.035 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.035 | 2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg00746322 | chr22:32000496 | SFI1 | 0.22 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg15791438 | chr22:31893238 | SFI1 | 0.035 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01701 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.055501 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 3 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0475838 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01602 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0349472 | 2.3E-05 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Previous decade consumption discovery | 5606 | cg08305533 | chr22:32007224 | SFI1 | NA | 2.3E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg15791438 | chr22:31893238 | SFI1 | 0.021 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 3 | 14671 | cg14773971 | chr22:31924660 | SFI1 | 0.035 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 2 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0468199 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6H7 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0552705 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0348385 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 1 | 14671 | cg14773971 | chr22:31924660 | SFI1 | 0.035 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.034824 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01766 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0554295 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P78563 | whole blood | OSCA model 3 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0472254 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 4 | 14671 | cg04835068 | chr22:31957393 | SFI1 | 0.051 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.047 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.047 | 2.7E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg16311410 | chr22:31892793 | SFI1 | 0.00019 | 2.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.035 | 2.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0345398 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 2 | 14671 | cg14773971 | chr22:31924660 | SFI1 | 0.034 | 2.9E-05 |
| Kazmi N | 31230546 | DNA methylation | Hypertensive disorders of pregnancy | Cord blood | Meta analysis adjusted model | 5242 | cg08305533 | chr22:32007224 | SFI1 | 0.006 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.034 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B7B8 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0545124 | 3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg13796737 | chr22:31968954 | SFI1 | 0.21 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0543942 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0456596 | 3.1E-05 |
| Battram T | 25424692 | DNA methylation | Smoking | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE50660. Never vs former smokers | 442 | cg08226295 | chr22:31892562 | SFI1 | -0.0056 | 3.1E-05 |
| Soloman O | 28556291 | DNA methylation | Prenatal phthalate exposure | Cord blood | 13 weeks gestation | 321 | cg23702117 | chr22:31897078 | SFI1 | -0.20327071 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 2 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0460939 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O43866 | whole blood | OSCA model 3 | 14671 | cg25218872 | chr22:31996918 | SFI1 | 0.034 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6H7 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.034075 | 3.7E-05 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg08305533 | chr22:32007224 | SFI1 | -0.00058139 | 3.7E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg00071692 | chr22:32006800 | SFI1 | 0.034 | 3.7E-05 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg15791438 | chr22:31893238 | SFI1 | -0.00063798 | 3.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01701 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0340356 | 3.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 1 | 14671 | cg02887506 | chr22:31927047 | SFI1 | -0.0340105 | 3.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 2 | 14671 | cg00746322 | chr22:32000496 | SFI1 | 0.038 | 3.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0339912 | 3.8E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg11409519 | chr22:32009686 | SFI1 | 0.2 | 3.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg01036541 | chr22:32009659 | SFI1 | 0.21 | 3.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02749 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.046 | 4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 2 | 14671 | cg25464687 | chr22:32010188 | SFI1 | -0.0347106 | 4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01766 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0456313 | 4.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01718 | whole blood | OSCA model 2 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0459994 | 4.1E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg23510357 | chr22:31934920 | SFI1 | 0.21 | 4.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0337878 | 4.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 3 | 14671 | cg25464687 | chr22:32010188 | SFI1 | -0.0344516 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg04835068 | chr22:31957393 | SFI1 | -0.0336833 | 4.5E-05 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Lifetime consumption discovery | 5606 | cg08305533 | chr22:32007224 | SFI1 | NA | 4.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.053 | 4.5E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | discovery | 18270 | cg13796737 | chr22:31968954 | SFI1 | 0.2 | 4.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.033596 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P36955 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.044 | 4.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg00071692 | chr22:32006800 | SFI1 | 0.035 | 4.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 4 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0496881 | 5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6H7 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0448291 | 5.1E-05 |
| Battram T | None | DNA methylation | Concentration of very small VLDL particles | Whole blood | None | 685 | cg08305533 | chr22:32007224 | SFI1 | -13000000.0 | 5.1E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg15791438 | chr22:31893238 | SFI1 | 2.3 | 5.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.033 | 5.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.033 | 5.1E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg04835068 | chr22:31957393 | SFI1 | -0.168859 | 5.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.033 | 5.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 3 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0347806 | 5.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0362159 | 5.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 2 | 14671 | cg02887506 | chr22:31927047 | SFI1 | -0.0334205 | 5.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg23510357 | chr22:31934920 | SFI1 | 0.21 | 5.4E-05 |
| Gadd DA | 35945220 | SPTAN1 protein levels (SeqId = 5031-10) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg00193210 | chr22:31985572 | SFI1 | 0.64 | 5.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg15791438 | chr22:31893238 | SFI1 | 0.033 | 5.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 3 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.045 | 5.6E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent Chronic Pain (Self-report) | Whole blood | Basic model | 18413 | cg13796737 | chr22:31968954 | SFI1 | 0.21 | 5.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01714 | whole blood | OSCA model 4 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0730011 | 5.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 3 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.033 | 5.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 4 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0489676 | 5.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 4 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.072 | 5.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B7B8 | whole blood | OSCA model 3 | 14671 | cg25218872 | chr22:31996918 | SFI1 | 0.033 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0331267 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | 0.033 | 6.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 3 | 14671 | cg02887506 | chr22:31927047 | SFI1 | -0.0328531 | 6.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.048 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg04835068 | chr22:31957393 | SFI1 | 0.035 | 6.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00071692 | chr22:32006800 | SFI1 | -0.032993 | 6.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg10511632 | chr22:32008959 | SFI1 | -0.0329595 | 6.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01700 | whole blood | OSCA model 4 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0722164 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg08941595 | chr22:31952631 | SFI1 | -0.0329257 | 6.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01701 | whole blood | OSCA model 1 | 14671 | cg08941595 | chr22:31952631 | SFI1 | 0.033 | 6.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg10511632 | chr22:32008959 | SFI1 | 0.033 | 6.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg22079361 | chr22:31979888 | SFI1 | 0.033 | 6.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg00071692 | chr22:32006800 | SFI1 | -0.0328249 | 7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01766 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0519686 | 7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 2 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0453565 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q08380 | whole blood | OSCA model 2 | 14671 | cg11435225 | chr22:32014422 | SFI1 | 0.033 | 7.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg08941595 | chr22:31952631 | SFI1 | -0.0337103 | 7.1E-05 |
| Gadd DA | 35945220 | APOB protein levels (SeqId = 2797-56) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02814896 | chr22:31892350 | SFI1 | -0.89 | 7.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.0326742 | 7.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg01332634 | chr22:31974816 | SFI1 | 0.034 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.051 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 1 | 14671 | cg07113062 | chr22:31943142 | SFI1 | 0.033 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | B1AHL2 | whole blood | OSCA model 4 | 14671 | cg02887506 | chr22:31927047 | SFI1 | -0.0341641 | 7.6E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Ischemic Heart Disease | Whole blood | Basic model | 17483 | cg14575131 | chr22:31933466 | SFI1 | -0.021 | 7.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg20441712 | chr22:32008978 | SFI1 | -0.0326169 | 7.8E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg04835068 | chr22:31957393 | SFI1 | -0.022 | 7.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01766 | whole blood | OSCA model 2 | 14671 | cg14575131 | chr22:31933466 | SFI1 | -0.0437519 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg10511632 | chr22:32008959 | SFI1 | -0.0325861 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg21806053 | chr22:32009606 | SFI1 | -0.0325825 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 3 | 14671 | cg13796737 | chr22:31968954 | SFI1 | 0.032 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg13796737 | chr22:31968954 | SFI1 | -0.0352303 | 8.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01700 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.051646 | 8.2E-05 |
| Gadd DA | 35945220 | LY9 protein levels (SeqId = 3324-51) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23510357 | chr22:31934920 | SFI1 | -0.86 | 8.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg00071692 | chr22:32006800 | SFI1 | 0.033 | 8.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q08380 | whole blood | OSCA model 1 | 14671 | cg11435225 | chr22:32014422 | SFI1 | 0.032 | 8.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg00193210 | chr22:31985572 | SFI1 | -0.123768 | 8.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg23049818 | chr22:31892356 | SFI1 | 0.032 | 8.4E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg12114049 | chr22:31892114 | SFI1 | 0.0013 | 8.4E-05 |
| Chatziioannou A | 28225026 | DNA methylation | Current vs never smoking | Whole blood | - | 454 | cg08305533 | chr22:32007224 | SFI1 | NA | 8.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02760 | whole blood | OSCA model 2 | 14671 | cg00193210 | chr22:31985572 | SFI1 | -0.044813 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 3 | 14671 | cg14575131 | chr22:31933466 | SFI1 | 0.042 | 8.7E-05 |
| Gadd DA | 35945220 | CST2 protein levels (SeqId = 4324-33) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg02814896 | chr22:31892350 | SFI1 | -0.87 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg00746322 | chr22:32000496 | SFI1 | -0.0323902 | 8.7E-05 |
| Gadd DA | 35945220 | FIGF protein levels (SeqId = 13098-93) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg23510357 | chr22:31934920 | SFI1 | 0.84 | 8.8E-05 |
| Hoang | 34516295 | DNA methylation | picloram | whole blood | discovery | 1011 | cg01168649 | chr22:31892074 | SFI1 | -0.0008 | 8.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg00193210 | chr22:31985572 | SFI1 | 0.047 | 8.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0A0MT89 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0323196 | 9E-05 |
| Battram T | None | DNA methylation | Triglycerides in very small VLDL | Whole blood | None | 680 | cg08305533 | chr22:32007224 | SFI1 | -3.2 | 9.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20851 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | 0.051 | 9.4E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg13796737 | chr22:31968954 | SFI1 | 0.19 | 9.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 2 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0509468 | 9.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6H7 | whole blood | OSCA model 3 | 14671 | cg07113062 | chr22:31943142 | SFI1 | -0.0437386 | 9.5E-05 |
| Battram T | None | DNA methylation | Total lipids in small VLDL | Whole blood | None | 681 | cg08305533 | chr22:32007224 | SFI1 | -0.55 | 9.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg25218872 | chr22:31996918 | SFI1 | 0.032 | 9.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg21806053 | chr22:32009606 | SFI1 | 0.032 | 9.6E-05 |
| Cronjé HT | 31910897 | DNA methylation | Low density lipoprotein cholesterol | Whole blood | None | 120 | cg24112255 | chr22:32009807 | SFI1 | 0.00069 | 9.6E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg20441712 | chr22:32008978 | SFI1 | -0.199366 | 9.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH25 | whole blood | OSCA model 1 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0321748 | 9.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 3 | 14671 | cg23510357 | chr22:31934920 | SFI1 | -0.0507705 | 9.9E-05 |
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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.
