Search results for SIRT1
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg03211233 | chr10:69644204 | SIRT1 | -7.3e-05 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg26075202 | chr10:69645177 | SIRT1 | -9.3e-05 | 0E+00 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg13796676 | chr10:69648687 | SIRT1 | 0.06 | 7E-45 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg00851987 | chr10:69664037 | SIRT1 | 0.024 | 9.2E-25 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg23988827 | chr10:69676715 | SIRT1 | 0.041 | 2.3E-20 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3249587 (gene symbol: SIRT1) | Whole blood | Meta-analysis | 4170 | cg00972288 | chr10:69644348 | SIRT1 | NA | 1.2E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg02720207 | chr10:69644399 | SIRT1 | -7e-05 | 2.4E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg00851987 | chr10:69664037 | SIRT1 | 0.00056 | 3.6E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01128800 | chr10:69644938 | SIRT1 | -7.8e-05 | 5E-11 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg26075202 | chr10:69645177 | SIRT1 | 0.0059 | 8.5E-11 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg01128800 | chr10:69644938 | SIRT1 | 0.0074 | 1.9E-10 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg10705386 | chr10:69644512 | SIRT1 | -0.00022 | 1.1E-09 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg05506809 | chr10:69648299 | SIRT1 | 0.033 | 5.3E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg00851987 | chr10:69664037 | SIRT1 | -0.00042 | 5.9E-09 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg23988827 | chr10:69676715 | SIRT1 | NA | 7.3E-09 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg00972288 | chr10:69644348 | SIRT1 | 0.033 | 8.7E-09 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg19980381 | chr10:69644128 | SIRT1 | 0.0092 | 2.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg12159502 | chr10:69643547 | SIRT1 | -0.0457181 | 3E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg23988827 | chr10:69676715 | SIRT1 | -0.03738 | 4.7E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg19192316 | chr10:69643020 | SIRT1 | -0.00063 | 4.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg25513531 | chr10:69644407 | SIRT1 | 0.045 | 5.3E-08 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg07832903 | chr10:69644926 | SIRT1 | 0.0051 | 1.3E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg05506809 | chr10:69648299 | SIRT1 | -0.0014 | 1.4E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg07832903 | chr10:69644926 | SIRT1 | -7.8e-05 | 2.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg12159502 | chr10:69643547 | SIRT1 | 0.041 | 6.8E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg00851987 | chr10:69664037 | SIRT1 | 0.0017 | 1.1E-06 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg10705386 | chr10:69644512 | SIRT1 | 1.3 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg25513531 | chr10:69644407 | SIRT1 | 0.039 | 1.9E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg00972288 | chr10:69644348 | SIRT1 | -0.00086 | 2.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg12159502 | chr10:69643547 | SIRT1 | -0.0386918 | 2.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg04869436 | chr10:69643265 | SIRT1 | -0.0382664 | 3.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg12159502 | chr10:69643547 | SIRT1 | -0.0377066 | 4.9E-06 |
| Neumann A | 33184255 | ADHD | DNA methylation | Cord Blood | At birth | 2477 | cg05506809 | chr10:69648299 | SIRT1 | -1.314 | 1.5E-05 |
| Hoang | 34516295 | DNA methylation | malathion | whole blood | discovery | 232 | cg08399593 | chr10:69650091 | SIRT1 | -0.01191 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg04869436 | chr10:69643265 | SIRT1 | -0.0353304 | 1.9E-05 |
| Gadd DA | 35945220 | BMP1 protein levels (SeqId = 3348-49) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg08399593 | chr10:69650091 | SIRT1 | 0.61 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg06108458 | chr10:69665196 | SIRT1 | 0.035 | 2.1E-05 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg05506809 | chr10:69648299 | SIRT1 | 0.011 | 3E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg25513531 | chr10:69644407 | SIRT1 | 0.00028 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg25513531 | chr10:69644407 | SIRT1 | -0.0342246 | 3.4E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg24705331 | chr10:69643200 | SIRT1 | 0.13 | 3.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg05506809 | chr10:69648299 | SIRT1 | 0.034 | 3.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg05506809 | chr10:69648299 | SIRT1 | 0.034 | 4.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg19980381 | chr10:69644128 | SIRT1 | -0.0334253 | 5.1E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg03251249 | chr10:69645012 | SIRT1 | 0.00016 | 5.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg04869436 | chr10:69643265 | SIRT1 | 0.033 | 5.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg04869436 | chr10:69643265 | SIRT1 | -0.0331023 | 6.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg25513531 | chr10:69644407 | SIRT1 | 0.033 | 7.7E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg07832903 | chr10:69644926 | SIRT1 | -1.09201 | 8.4E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg13796676 | chr10:69648687 | SIRT1 | -0.0865649 | 8.6E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg23988827 | chr10:69676715 | SIRT1 | -0.011 | 9E-05 |
| Sharp G | 33517419 | DNA methylation | Paternal body mass index | Cord blood | Adjusted for maternal BMI using cord blood in males only | 2530 | cg01128800 | chr10:69644938 | SIRT1 | -0.0003 | 9.1E-05 |
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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.
