EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for SLC7A11

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg04474257 chr4:139147773 SLC7A11 -0.0026 0E+00
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Discovery and replication 3187 cg06690548 chr4:139162808 SLC7A11 -0.04 0E+00
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Discovery and replication adjusted for surrogate variables 3187 cg06690548 chr4:139162808 SLC7A11 -0.043 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg07661704 chr4:139144433 SLC7A11 0.0033 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg07661704 chr4:139144433 SLC7A11 -0.013 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg21877274 chr4:139107328 SLC7A11 -0.00095 0E+00
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg04487857 chr4:139096540 SLC7A11 0.58 1.6E-144
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg06690548 chr4:139162808 SLC7A11 -0.499254 4.4E-112
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg07661704 chr4:139144433 SLC7A11 -0.28741 3.3E-103
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg06690548 chr4:139162808 SLC7A11 -0.47579 3.7E-103
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg06690548 chr4:139162808 SLC7A11 -0.451347 6.2E-100
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg06690548 chr4:139162808 SLC7A11 -0.458385 2.9E-95
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg06690548 chr4:139162808 SLC7A11 -0.427507 3.8E-90
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg06690548 chr4:139162808 SLC7A11 NA 1.4E-86
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg06690548 chr4:139162808 SLC7A11 -0.417194 5E-86
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.158033 1.1E-82
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg06690548 chr4:139162808 SLC7A11 -3.0 3E-79
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg00534274 chr4:139163341 SLC7A11 0.15 2.5E-78
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg02102889 chr4:139164723 SLC7A11 0.29 4.4E-77
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg21877274 chr4:139107328 SLC7A11 -0.05869 1.5E-76
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous decade consumption discovery 5606 cg06690548 chr4:139162808 SLC7A11 NA 7.4E-70
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg15867963 chr4:139143309 SLC7A11 0.25 7E-66
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.15 1.8E-63
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.13 4E-59
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.130937 4.1E-57
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.13 7.8E-55
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.13 6.5E-54
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.125344 1.9E-52
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.125566 1.7E-51
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.133469 3.3E-51
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.12 2E-50
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.12 8.2E-47
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.12 1.6E-46
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Lifetime consumption discovery 5606 cg06690548 chr4:139162808 SLC7A11 NA 6.2E-46
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.114277 1.3E-41
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.111791 4.4E-41
Petersen A-K 24014485 M37202_4-androsten-3betacomma17beta-diol_disulfate_1* DNA methylation Whole blood no snps model 1760 cg06690548 chr4:139162808 SLC7A11 -0.98 2.7E-40
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg15441006 chr4:139110589 SLC7A11 -0.12183 1.5E-39
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.11 2.7E-39
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 -0.107648 4.5E-39
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg24869834 chr4:139146513 SLC7A11 -0.08466 4.6E-39
Petersen A-K 24014485 M37202_4-androsten-3betacomma17beta-diol_disulfate_1* DNA methylation Whole blood snps as covariates model 1760 cg06690548 chr4:139162808 SLC7A11 -0.98 6.8E-39
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg06690548 chr4:139162808 SLC7A11 -0.287347 2.2E-38
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.106469 3E-38
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.11 4.4E-38
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood discovery 17908 cg06690548 chr4:139162808 SLC7A11 -0.269361 2.3E-37
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.11 6.4E-36
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.1 1E-35
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.1 1.3E-35
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.102856 6.9E-35
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.102852 7.5E-35
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.108469 1.5E-34
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.100861 1.7E-34
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 0.1 2.4E-34
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.1 3.3E-34
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg01309945 chr4:139126892 SLC7A11 -0.02683 6.5E-34
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg06690548 chr4:139162808 SLC7A11 0.08 9E-34
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.1 1.2E-33
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0991242 2.3E-33
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.099 2.4E-33
Richard MA 29198723 DNA methylation Systolic Blood Pressure Whole blood, CD4+ T cells Meta-analysis 17010 cg06690548 chr4:139162808 SLC7A11 -0.0002 1.6E-32
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.104795 3.9E-32
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0968689 6.3E-32
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.095 1.1E-31
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.098 1.1E-31
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.096 1.1E-31
Liu C 27843151 DNA methylation Alcohol consumption per day CD14+ monocytes CD14+ monocytes 1251 cg06690548 chr4:139162808 SLC7A11 -0.00107 1.2E-31
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg04487857 chr4:139096540 SLC7A11 2.0 1.3E-31
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.1 2.1E-31
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.09769 6.4E-31
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0961098 1E-30
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0958064 1.8E-30
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0976729 1.9E-30
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0944576 2E-30
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.100931 4.2E-30
Xu K 31386212 DNA methylation Alcohol Consumption Saliva adjusted for bmi 1135 cg06690548 chr4:139162808 SLC7A11 NA 7.4E-30
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0934316 8.3E-30
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.093 6.8E-29
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0931223 7.1E-29
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg06690548 chr4:139162808 SLC7A11 -0.23993 1.7E-28
Xu K 31386212 DNA methylation Alcohol Consumption Saliva not adjusted for bmi 1135 cg06690548 chr4:139162808 SLC7A11 NA 2.7E-28
Sayols-Baixeras S 29099282 Waist circumference DNA methylation Whole blood Meta-analysis model 2 3156 cg06690548 chr4:139162808 SLC7A11 -2.2 3.8E-28
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0915021 5.5E-28
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.089 1.5E-27
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg07661704 chr4:139144433 SLC7A11 1.8 2E-27
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.09117 4.1E-27
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0885039 6.6E-27
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.088 8.8E-27
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg06206831 chr4:139103485 SLC7A11 -0.02082 2E-26
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0874435 2.7E-26
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0872641 3.3E-26
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.087 5E-26
Richard MA 29198723 DNA methylation Diastolic Blood Pressure Whole blood, CD4+ T cells Meta-analysis 17010 cg06690548 chr4:139162808 SLC7A11 -0.0003 7.9E-26
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg07661704 chr4:139144433 SLC7A11 0.27 2.3E-25
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg06690548 chr4:139162808 SLC7A11 -0.046 2.9E-25
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0853796 5.7E-25
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.085 6.4E-25
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.084 2.4E-24
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 -0.0837132 3.1E-24
Gadd DA 35945220 PSAT1 protein levels (SeqId = 18342-2) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -1.01 3.8E-24
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0832376 5.6E-24
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.084 7.7E-24
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg07661704 chr4:139144433 SLC7A11 0.26 1E-23
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg06690548 chr4:139162808 SLC7A11 -0.205637 1.7E-23
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0831583 2.6E-23
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0817437 3.5E-23
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.082 4.1E-23
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0806104 4.1E-23
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.087 4.7E-23
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.082 5.3E-23
Nano J 28624579 DNA methylation Gamma-glutamyl transferase Peripheral blood Meta-analysis 1450 cg06690548 chr4:139162808 SLC7A11 -0.012 1.2E-22
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0866668 1.3E-22
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0827501 1.4E-22
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg07661704 chr4:139144433 SLC7A11 0.25 2.1E-22
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg13903162 chr4:139163019 SLC7A11 -0.348169 2.7E-22
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 0.08 3.1E-22
Gadd DA 35945220 SCUBE1 protein levels (SeqId = 8989-40) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.96 3.9E-22
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Replication adjusted for surrogate variables 2542 cg06690548 chr4:139162808 SLC7A11 -0.044 5.4E-22
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0805935 5.6E-22
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0790032 9.4E-22
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.08 1E-21
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg13903162 chr4:139163019 SLC7A11 -2.5 1.6E-21
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg13903162 chr4:139163019 SLC7A11 -0.309354 1.9E-21
Sayols-Baixeras S 29099282 Waist circumference DNA methylation Whole blood Meta-analysis model 1 3156 cg06690548 chr4:139162808 SLC7A11 -1.9 2.1E-21
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg13903162 chr4:139163019 SLC7A11 -0.341374 2.4E-21
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0781758 2.5E-21
Wahl S 28002404 Body mass index DNA methylation Whole blood Discovery and replication 10238 cg06690548 chr4:139162808 SLC7A11 NA 2.5E-21
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0790965 2.6E-21
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0780124 3E-21
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.078 3.5E-21
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 0.078 5E-21
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0781422 7.8E-21
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0780909 7.8E-21
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg13903162 chr4:139163019 SLC7A11 -0.303769 1.3E-20
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0783068 1.4E-20
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Replication 2542 cg06690548 chr4:139162808 SLC7A11 -0.042 1.5E-20
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.076 2.2E-20
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg13903162 chr4:139163019 SLC7A11 -0.329323 3.2E-20
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.077 4.9E-20
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery 2306 cg06690548 chr4:139162808 SLC7A11 -0.0218554 7E-20
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.077 7.5E-20
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.078998 1E-19
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg13903162 chr4:139163019 SLC7A11 -0.295603 1.1E-19
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery and replication 4261 cg06690548 chr4:139162808 SLC7A11 -0.0123339 1.8E-19
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg15867963 chr4:139143309 SLC7A11 0.0013 2.3E-19
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0737611 3.7E-19
Wahl S 28002404 Body mass index DNA methylation Whole blood European ancestry discovery 2707 cg06690548 chr4:139162808 SLC7A11 -19.0 4.4E-19
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0734747 5.1E-19
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0774828 5.1E-19
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0744782 5.3E-19
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.073 6.4E-19
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.073 6.4E-19
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0726341 1.3E-18
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.074 1.5E-18
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.077 2.6E-18
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0753227 2.6E-18
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.072 3.6E-18
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg06690548 chr4:139162808 SLC7A11 -1.5 5.1E-18
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0765002 8.6E-18
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 0.07 1.4E-17
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg07661704 chr4:139144433 SLC7A11 -0.214092 1.7E-17
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.071088 1.7E-17
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.075 2.2E-17
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 -0.0699428 2.2E-17
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0713691 3.5E-17
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.069 3.8E-17
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg06690548 chr4:139162808 SLC7A11 -0.081 6.9E-17
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.074298 7.3E-17
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0686907 8.1E-17
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg06623625 chr4:139137902 SLC7A11 0.31 8.4E-17
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0679931 2E-16
Gomez-Alonso MDC 33413638 DNA methylation LAtoFA Whole blood Meta-analysis 5414 cg06690548 chr4:139162808 SLC7A11 0.52 2E-16
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.068 2.9E-16
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.068 4.6E-16
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0669321 4.8E-16
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 0.067 1.4E-15
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery adjusted for BMI 2306 cg06690548 chr4:139162808 SLC7A11 -0.0198334 1.5E-15
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 0.067 1.6E-15
Jiantao Ma 30796027 DNA methylation hepatic fat whole blood Discovery 1496 cg06690548 chr4:139162808 SLC7A11 NA 1.8E-15
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.066 1.9E-15
Gomez-Alonso MDC 33413638 DNA methylation FAw6toFA Whole blood Meta-analysis 5414 cg06690548 chr4:139162808 SLC7A11 0.43 2.7E-15
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.069 3.1E-15
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0651233 6.2E-15
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 -0.0637106 1.1E-14
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 -0.063706 1.1E-14
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 0.064 1.3E-14
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 -0.0634141 1.5E-14
Nano J 28624579 DNA methylation Gamma-glutamyl transferase Peripheral blood Discovery 731 cg06690548 chr4:139162808 SLC7A11 -0.011 1.5E-14
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.063 1.6E-14
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 0.063 1.7E-14
Sayols-Baixeras S 29099282 Body mass index DNA methylation Whole blood Meta-analysis model 2 3156 cg06690548 chr4:139162808 SLC7A11 -0.71 2E-14
Ma J 30936141 DNA methylation Hepatic Fat Whole blood Meta-analysis model 2 3400 cg06690548 chr4:139162808 SLC7A11 NA 2.3E-14
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.063 2.5E-14
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.062 4.5E-14
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.064 4.9E-14
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 0.063 5.2E-14
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.06213 6E-14
Ma J 30936141 DNA methylation Hepatic Fat Whole blood Meta-analysis model 1 3400 cg06690548 chr4:139162808 SLC7A11 NA 6.8E-14
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery and replication adjusted for BMI 4261 cg06690548 chr4:139162808 SLC7A11 -0.0107 7.5E-14
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.062 7.9E-14
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.062 8.1E-14
Gadd DA 35945220 PRSS2 protein levels (SeqId = 5034-79) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.74 1E-13
Ligthart S 27955697 DNA methylation C-reactive protein Whole blood Discovery 8863 cg06690548 chr4:139162808 SLC7A11 -0.0048 1.2E-13
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0612472 1.3E-13
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0627277 1.3E-13
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0656609 1.4E-13
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.061 1.4E-13
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.06 2.3E-13
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.062 2.4E-13
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0612957 2.4E-13
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.062 2.4E-13
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.065 2.6E-13
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 0.06 3E-13
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.064 3E-13
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg07109838 chr4:139106603 SLC7A11 -0.247264 3.9E-13
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0615995 4.1E-13
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.065 4.7E-13
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg04474257 chr4:139147773 SLC7A11 0.06 5.2E-13
Sayols-Baixeras S 29099282 Body mass index DNA methylation Whole blood Meta-analysis model 1 3156 cg06690548 chr4:139162808 SLC7A11 -0.63 6.9E-13
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0590529 8.2E-13
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.0598587 8.4E-13
Wahl S 28002404 Body mass index DNA methylation Whole blood All ancestry replication 4851 cg06690548 chr4:139162808 SLC7A11 -11.7 1E-12
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 -0.0642069 1.1E-12
Gadd DA 35945220 ALDOB protein levels (SeqId = 18185-118) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.71 1.2E-12
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.061073 1.4E-12
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 -0.0583848 1.5E-12
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.058 1.5E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0583242 1.6E-12
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Fully-adjusted model 13971 cg06690548 chr4:139162808 SLC7A11 -0.034 1.7E-12
Liu J 31197173 DNA methylation fasting glucose whole blood Base 4808 cg06690548 chr4:139162808 SLC7A11 -1.98 1.8E-12
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.058 1.9E-12
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0580661 1.9E-12
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.06 2.4E-12
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.0577882 2.5E-12
Gadd DA 35945220 ACY1 protein levels (SeqId = 3343-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.7 2.7E-12
Mendelson MM 28095459 DNA methylation Body mass index Whole blood Meta-analysis 3743 cg06690548 chr4:139162808 SLC7A11 NA 2.8E-12
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg02734904 chr4:139145210 SLC7A11 -0.0163 3E-12
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.057 4.2E-12
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 -0.0571607 4.3E-12
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0609807 4.5E-12
Gadd DA 35945220 PRG3 protein levels (SeqId = 9015-1) DNA methylation Whole blood SomaScan protein measurement 774 cg13903162 chr4:139163019 SLC7A11 -1.11 4.8E-12
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg00534274 chr4:139163341 SLC7A11 -1.3 5E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.057 5.4E-12
Josephine Robertson 41361833 DNA methylation P01344 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0614283 5.9E-12
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg06690548 chr4:139162808 SLC7A11 -0.072 6E-12
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0608253 6E-12
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.057804 6.1E-12
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0577979 6.2E-12
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 0.057 7.1E-12
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0565116 7.4E-12
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0565907 7.8E-12
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg07661704 chr4:139144433 SLC7A11 0.036 7.9E-12
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg04474257 chr4:139147773 SLC7A11 0.056 8.1E-12
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.056 9.2E-12
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.057 9.8E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 0.057 1E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.056 1.2E-11
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0597696 1.3E-11
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 -0.0557157 1.4E-11
Nano J 28624579 DNA methylation Alanine aminotransferase Peripheral blood Meta-analysis 1450 cg06690548 chr4:139162808 SLC7A11 -0.012 1.9E-11
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg00534274 chr4:139163341 SLC7A11 -0.123481 2E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.055 2E-11
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.055702 2.4E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 0.055 2.7E-11
Josephine Robertson 41361833 DNA methylation P05160 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0555088 3.3E-11
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.054 4.2E-11
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 0.054 5E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 -0.0541525 5.3E-11
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.0540685 5.6E-11
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.0548003 5.6E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0539483 6.1E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 0.054 6.2E-11
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.055 6.5E-11
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.054 6.7E-11
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg07661704 chr4:139144433 SLC7A11 0.19 7.4E-11
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.054 7.5E-11
Gadd DA 35945220 PAPPA protein levels (SeqId = 4148-49) DNA methylation Whole blood SomaScan protein measurement 774 cg13903162 chr4:139163019 SLC7A11 -1.04 7.9E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 0.054 8.6E-11
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.054 9.2E-11
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.055 9.5E-11
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.053 9.6E-11
Gadd DA 35945220 APOC3 protein levels (SeqId = 6461-54) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.64 9.9E-11
Josephine Robertson 41361833 DNA methylation P05160 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0548438 1.1E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg04487857 chr4:139096540 SLC7A11 -0.00055 1.1E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg06623625 chr4:139137902 SLC7A11 -0.00062 1.2E-10
Wahl S 28002404 Body mass index DNA methylation Whole blood European ancestry replication 4195 cg06690548 chr4:139162808 SLC7A11 -10.11 1.3E-10
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.054 1.4E-10
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.053738 1.5E-10
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 -0.0528657 1.5E-10
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg13903162 chr4:139163019 SLC7A11 -0.055 1.5E-10
Gadd DA 35945220 ADSSL1 protein levels (SeqId = 13998-26) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.637 1.6E-10
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.053 1.7E-10
Josephine Robertson 41361833 DNA methylation P05160 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0526531 1.8E-10
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg07661704 chr4:139144433 SLC7A11 0.19 2.1E-10
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg13028471 chr4:139163535 SLC7A11 0.008 2.3E-10
Gadd DA 35945220 DEFB1 protein levels (SeqId = 6629-3) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.628 2.8E-10
Gadd DA 35945220 RBP5 protein levels (SeqId = 19241-31) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.63 2.9E-10
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.051979 3E-10
Wahl S 28002404 Body mass index DNA mehtylation Whole blood All ancestry discovery 5387 cg06690548 chr4:139162808 SLC7A11 -6.3 3E-10
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 0.052 3E-10
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.053 3E-10
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0523897 3.1E-10
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0518867 3.2E-10
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.052 3.3E-10
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0526582 3.3E-10
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 0.052 3.6E-10
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0524078 3.8E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.0515044 4.3E-10
Josephine Robertson 41361833 DNA methylation P05160 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.055776 4.4E-10
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.051 4.6E-10
Darina Czamara 38600394 DNA methylation sex placenta meta-analysis of robust linear regression results per cohort 746 cg13903162 chr4:139163019 SLC7A11 -0.1719049 4.6E-10
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.052 5.2E-10
Liang X 32034291 DNA methylation Alcohol Consumption Whole blood Meta analysis with phosphatidylethanol used as measure for AC 1047 cg06690548 chr4:139162808 SLC7A11 NA 5.5E-10
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.0517969 5.6E-10
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.051 6.5E-10
Gadd DA 35945220 ASGR1 protein levels (SeqId = 5452-71) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.61 6.6E-10
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 -0.0508804 7E-10
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0516161 7.1E-10
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.055 7.3E-10
Gadd DA 35945220 ENPP7 protein levels (SeqId = 4435-66) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.61 7.9E-10
Liu J 31197173 DNA methylation fasting insulin whole blood Base 4808 cg06690548 chr4:139162808 SLC7A11 -1.74 8.9E-10
Gadd DA 35945220 RBP4 protein levels (SeqId = 15633-6) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.61 1E-09
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.054 1.2E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg01309945 chr4:139126892 SLC7A11 -0.00052 1.3E-09
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0487614 1.5E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Kidney Disease (Estimated) Whole blood Basic model 18318 cg06690548 chr4:139162808 SLC7A11 -0.044 1.6E-09
Imgenberg-Kreuz J 26857698 DNA methylation Primary Sjogrens syndrome Whole blood Whole blood 500 cg07661704 chr4:139144433 SLC7A11 NA 1.6E-09
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.05 1.7E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 -0.0496881 1.7E-09
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.05 1.7E-09
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.0502791 1.8E-09
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0494291 2.1E-09
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0494154 2.1E-09
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0493928 2.2E-09
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 -0.0493892 2.2E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0503415 2.4E-09
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.049 2.4E-09
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.0499608 2.4E-09
Josephine Robertson 41361833 DNA methylation P01344 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0506803 2.4E-09
Liu C 27843151 DNA methylation Alcohol consumption per day Whole blood European ancestry 9643 cg04487857 chr4:139096540 SLC7A11 0.00011 2.7E-09
Gadd DA 35945220 CES1 protein levels (SeqId = 15487-164) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.59 2.7E-09
Gadd DA 35945220 CBLN1 protein levels (SeqId = 9313-27) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 0.59 2.8E-09
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.0490142 2.9E-09
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0500257 3.6E-09
Liu C 27843151 DNA methylation Alcohol consumption per day Whole blood European ancestry 9643 cg06690548 chr4:139162808 SLC7A11 -0.00133477 3.9E-09
Nano J 28624579 DNA methylation Gamma-glutamyl transferase Peripheral blood Replication 719 cg06690548 chr4:139162808 SLC7A11 -0.015 3.9E-09
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.048366 4.6E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg04474257 chr4:139147773 SLC7A11 0.0019 4.7E-09
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.048 4.7E-09
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.05 4.7E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 -0.0483084 4.8E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.05 4.9E-09
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0514451 5.2E-09
Liu J 31197173 DNA methylation fasting glucose whole blood Base plus BMI 4808 cg06690548 chr4:139162808 SLC7A11 -1.58 5.5E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.048 5.6E-09
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0486412 6E-09
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg00361146 chr4:139163780 SLC7A11 -0.02961 6.1E-09
Gadd DA 35945220 OXT protein levels (SeqId = 8356-88) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.58 6.2E-09
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 -0.0479258 6.3E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 0.048 6.5E-09
Gadd DA 35945220 AKR1C4 protein levels (SeqId = 18397-5) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.58 6.6E-09
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.0484952 7E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 -0.0477804 7E-09
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.049 7E-09
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 0.048 7.4E-09
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.049 7.9E-09
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.047 9E-09
Ma J 30936141 Nonalcoholic fatty liver disease DNA methylation Whole Blood, Monocytes discovery and replication 4525 cg06690548 chr4:139162808 SLC7A11 NA 9.3E-09
Ma J 30936141 DNA methylation Hepatic Fat Whole blood Meta-analysis model 3 3400 cg06690548 chr4:139162808 SLC7A11 NA 9.3E-09
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg01309945 chr4:139126892 SLC7A11 0.11 9.9E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 0.047 1E-08
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg00361146 chr4:139163780 SLC7A11 0.02 1E-08
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 0.047 1.1E-08
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg24869834 chr4:139146513 SLC7A11 -0.02959 1.1E-08
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg07661704 chr4:139144433 SLC7A11 0.17 1.1E-08
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.0470843 1.2E-08
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 -0.0470613 1.2E-08
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg00534274 chr4:139163341 SLC7A11 -0.105081 1.2E-08
Priyanka Choudhary 38052982 DNA methylation Maternal education at the time of pregnancy Cord blood Model1_Cord_All 9881 cg00534274 chr4:139163341 SLC7A11 0.00094 1.3E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 0.047 1.3E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 0.047 1.3E-08
Nabais MF 33771206 DNA methylation Neurodegenerative disorders Whole blood Meta-analysis of ALS, AD, PD 7322 cg06690548 chr4:139162808 SLC7A11 0.52 1.4E-08
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.048 1.4E-08
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.047 1.4E-08
Gadd DA 35945220 SULT2A1 protein levels (SeqId = 9829-91) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.56 1.5E-08
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 -0.0466524 1.6E-08
Gadd DA 35945220 AKR7A3 protein levels (SeqId = 18173-11) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.56 1.6E-08
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 0.047 1.7E-08
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0479915 1.7E-08
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 -0.0465586 1.7E-08
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg04487857 chr4:139096540 SLC7A11 -0.16139 1.7E-08
Nano J 28624579 DNA methylation Alanine aminotransferase Peripheral blood Discovery 731 cg06690548 chr4:139162808 SLC7A11 -0.013 1.8E-08
Priyanka Choudhary 38052982 DNA methylation Maternal education at the time of pregnancy Cord blood Model1_Cord_European 9501 cg00534274 chr4:139163341 SLC7A11 0.00096 1.9E-08
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.047 2E-08
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0467191 2.3E-08
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg21877274 chr4:139107328 SLC7A11 -0.59239265 2.4E-08
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.0465224 2.4E-08
Nicolas Fragoso-Bargas 36534481 DNA methylation HOMA-IR Whole blood discovery 456 cg06690548 chr4:139162808 SLC7A11 -0.153536729 2.5E-08
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.047 2.5E-08
Gadd DA 35945220 FBP1 protein levels (SeqId = 7206-20) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.55 2.7E-08
Gadd DA 35945220 ASL protein levels (SeqId = 11241-8) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.55 2.8E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 0.046 2.8E-08
Nicolas Fragoso-Bargas 36534481 DNA methylation HOMA-IR Whole blood discovery (european) 294 cg06690548 chr4:139162808 SLC7A11 -0.195339535 2.9E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.049 3E-08
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg00534274 chr4:139163341 SLC7A11 -0.101905 3E-08
Gadd DA 35945220 SIGLEC7 protein levels (SeqId = 2742-68) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.55 3.4E-08
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 0.046 3.4E-08
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.045 3.6E-08
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0454053 3.8E-08
Josephine Robertson 41361833 DNA methylation P01344 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0460198 3.8E-08
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.046 3.8E-08
Braun KVE 28194238 DNA methylation Triglycerides Whole blood Discovery and replication 1485 cg06690548 chr4:139162808 SLC7A11 -0.0089 3.9E-08
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.045 4E-08
Song N 33823916 DNA methylation Cancer treatment: Asparaginase enzymes and epipodophyllotoxins Whole blood None 2052 cg07661704 chr4:139144433 SLC7A11 0.099 4.3E-08
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.049 4.3E-08
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 -0.0451694 4.4E-08
Gadd DA 35945220 CELA2A protein levels (SeqId = 7140-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.54 4.7E-08
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 -0.0514247 4.7E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg04487857 chr4:139096540 SLC7A11 0.23 4.8E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg06206831 chr4:139103485 SLC7A11 0.00064 5.1E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.0455687 5.1E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Kidney Disease (Estimated) Whole blood Fully-adjusted Model 14315 cg06690548 chr4:139162808 SLC7A11 -0.042 5.7E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 -0.04469 6.1E-08
Vallerga CL 32144264 Parkinson's disease DNA methylation Whole blood Meta analysis using MOA model from OSCA 2131 cg06690548 chr4:139162808 SLC7A11 1.1 6.2E-08
Gadd DA 35945220 BOC protein levels (SeqId = 4328-2) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 0.54 6.2E-08
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0457627 6.4E-08
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg13028471 chr4:139163535 SLC7A11 0.011 6.7E-08
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 -0.0507734 6.9E-08
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg13903162 chr4:139163019 SLC7A11 -0.192074 7.3E-08
Gadd DA 35945220 OMD protein levels (SeqId = 5358-3) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 0.53 8E-08
Gadd DA 35945220 FAH protein levels (SeqId = 11424-4) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.53 8.1E-08
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.044 8.5E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg04474257 chr4:139147773 SLC7A11 0.044 9.8E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg07661704 chr4:139144433 SLC7A11 -0.15454 1E-07
Gadd DA 35945220 PTPRJ protein levels (SeqId = 8250-2) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.53 1E-07
Gadd DA 35945220 CCL16 protein levels (SeqId = 4913-78) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.53 1E-07
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 -0.0439142 1E-07
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.044 1.1E-07
Gadd DA 35945220 IGF2R protein levels (SeqId = 16057-6) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.53 1.1E-07
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.043 1.1E-07
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.043747 1.2E-07
Gadd DA 35945220 ART4 protein levels (SeqId = 6576-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.53 1.2E-07
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0471163 1.2E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.044 1.2E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.044 1.2E-07
Mendelson MM 28095459 DNA methylation Body mass index Whole blood Framingham Heart Study Batch 2 1935 cg06690548 chr4:139162808 SLC7A11 -0.0217 1.3E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.044 1.3E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 0.048 1.3E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 -0.0433952 1.5E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.0433527 1.5E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 -0.0433333 1.5E-07
Ligthart S 27955697 DNA methylation C-reactive protein Whole blood Replication 4111 cg06690548 chr4:139162808 SLC7A11 -0.0029 1.5E-07
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0432313 1.6E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg04487857 chr4:139096540 SLC7A11 -0.0433736 1.6E-07
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0446341 1.6E-07
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.043 1.6E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg00534274 chr4:139163341 SLC7A11 -0.02 1.9E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg06690548 chr4:139162808 SLC7A11 -0.054 1.9E-07
Ding, Yuan Chun 34425644 DNA methylation Polybrominated diphenyl ethers (PBDEs) Whole blood Discovery 313 cg05371417 chr4:139113574 SLC7A11 -0.007 1.9E-07
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.043 2E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.043 2E-07
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 -0.0428393 2.1E-07
Gadd DA 35945220 HRSP12 protein levels (SeqId = 14636-25) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.52 2.1E-07
Gadd DA 35945220 ADH4 protein levels (SeqId = 8325-37) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.52 2.2E-07
Battram T None DNA methylation VLDL cholesterol Whole blood fasting 678 cg06690548 chr4:139162808 SLC7A11 -0.94 2.2E-07
Josephine Robertson 41361833 DNA methylation P01344 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0427353 2.2E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.046 2.3E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 -0.0427157 2.3E-07
Battram T None DNA methylation Triglycerides Whole blood fasting 678 cg06690548 chr4:139162808 SLC7A11 -0.43 2.3E-07
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 -0.0484507 2.4E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg15867963 chr4:139143309 SLC7A11 0.043 2.6E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg06690548 chr4:139162808 SLC7A11 -0.019 2.8E-07
Gadd DA 35945220 DCXR protein levels (SeqId = 17758-79) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.51 2.8E-07
Yang BZ 23332324 DNA methylation Child abuse Saliva - 192 cg15441006 chr4:139110589 SLC7A11 NA 2.8E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0452308 3E-07
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg07109838 chr4:139106603 SLC7A11 -0.174856 3E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.042 3.2E-07
Gadd DA 35945220 HMGCS2 protein levels (SeqId = 13704-5) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.51 3.5E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 -0.0464777 3.5E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0430101 3.7E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg07661704 chr4:139144433 SLC7A11 0.041 3.7E-07
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 -0.0419362 3.7E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg07661704 chr4:139144433 SLC7A11 -0.0422975 3.8E-07
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg07109838 chr4:139106603 SLC7A11 -0.172799 3.9E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg00534274 chr4:139163341 SLC7A11 -0.100511 3.9E-07
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.042 4.1E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg00534274 chr4:139163341 SLC7A11 -0.0417893 4.1E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg00534274 chr4:139163341 SLC7A11 -0.028 4.5E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg11788572 chr4:139111673 SLC7A11 0.069 4.6E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0446477 4.6E-07
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Discovery adjusted for surrogate variables 645 cg06690548 chr4:139162808 SLC7A11 -0.04 4.9E-07
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.042 4.9E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg00534274 chr4:139163341 SLC7A11 -0.0414716 5E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg02734904 chr4:139145210 SLC7A11 -0.00075 5.2E-07
Gadd DA 35945220 GSTA1 protein levels (SeqId = 17138-8) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.5 5.4E-07
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.041 5.7E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 0.041 5.8E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg11788572 chr4:139111673 SLC7A11 -0.0674758 5.9E-07
Gadd DA 35945220 GBP1 protein levels (SeqId = 15326-64) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.49 6E-07
Gadd DA 35945220 HERC5 protein levels (SeqId = 12934-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.496 6.2E-07
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg06623625 chr4:139137902 SLC7A11 0.012 6.3E-07
Gadd DA 35945220 OTC protein levels (SeqId = 15431-31) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.5 6.4E-07
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 0.041 6.5E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg11788572 chr4:139111673 SLC7A11 0.068 6.5E-07
Gadd DA 35945220 CHAD protein levels (SeqId = 13460-4) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 0.5 6.5E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg15867963 chr4:139143309 SLC7A11 0.0037 6.5E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg13903162 chr4:139163019 SLC7A11 0.042 6.6E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg04474257 chr4:139147773 SLC7A11 0.041 6.7E-07
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.041 6.8E-07
Gadd DA 35945220 CNDP1 protein levels (SeqId = 5456-59) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.49 7E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 -0.0408728 7.3E-07
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 -0.0408723 7.3E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 0.045 7.4E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 -0.0408646 7.4E-07
Gadd DA 35945220 SELE protein levels (SeqId = 3470-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.49 7.5E-07
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 -0.0455732 7.5E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg15867963 chr4:139143309 SLC7A11 0.041 7.6E-07
Gadd DA 35945220 AKR1D1 protein levels (SeqId = 18398-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.49 7.6E-07
Gadd DA 35945220 LGALS9 protein levels (SeqId = 9197-4) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.49 7.7E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Osteoarthritis Whole blood Basic model 16114 cg06690548 chr4:139162808 SLC7A11 -0.037 7.8E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.041 8.1E-07
Gadd DA 35945220 QRFP protein levels (SeqId = 6463-59) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.49 8.2E-07
Gadd DA 35945220 EFS protein levels (SeqId = 12572-236) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.49 8.5E-07
Gadd DA 35945220 ALDH2 protein levels (SeqId = 18381-16) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.49 8.6E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg00534274 chr4:139163341 SLC7A11 0.088 8.6E-07
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 -0.0405494 9E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg07661704 chr4:139144433 SLC7A11 -0.0409964 9.2E-07
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 -0.0404405 9.6E-07
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 0.04 9.9E-07
Gadd DA 35945220 ALDH1A1 protein levels (SeqId = 11265-8) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.49 9.9E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg15867963 chr4:139143309 SLC7A11 0.04 1E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0414855 1.1E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0415277 1.1E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.04 1.1E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg11788572 chr4:139111673 SLC7A11 1.5 1.1E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 -0.0400889 1.2E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0413063 1.2E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg07661704 chr4:139144433 SLC7A11 0.04 1.2E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.042 1.3E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg13903162 chr4:139163019 SLC7A11 -0.072 1.3E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg02559773 chr4:139157773 SLC7A11 0.04 1.4E-06
Gadd DA 35945220 C5orf38 protein levels (SeqId = 6378-2) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.48 1.4E-06
Gadd DA 35945220 PRSS8 protein levels (SeqId = 15513-108) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.48 1.4E-06
Gadd DA 35945220 IGFBP4 protein levels (SeqId = 2950-57) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.48 1.5E-06
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.04 1.5E-06
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.041 1.5E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg04487857 chr4:139096540 SLC7A11 -0.0394303 1.8E-06
Gadd DA 35945220 CHST9 protein levels (SeqId = 11646-4) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.476 1.8E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg13903162 chr4:139163019 SLC7A11 -0.027 1.8E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.039 1.9E-06
Gadd DA 35945220 CFHR1 protein levels (SeqId = 15468-14) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.47 1.9E-06
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.039 1.9E-06
Gadd DA 35945220 SLAMF6 protein levels (SeqId = 5128-53) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.47 2E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg15867963 chr4:139143309 SLC7A11 -0.0391537 2.1E-06
Sharp G 33517419 DNA methylation Maternal body mass index Cord blood Unadjusted for paternal BMI using cord blood 4894 cg00534274 chr4:139163341 SLC7A11 -0.00375 2.1E-06
Gadd DA 35945220 HMGCS1 protein levels (SeqId = 13496-19) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.47 2.1E-06
Gadd DA 35945220 LRRTM4 protein levels (SeqId = 8646-61) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.47 2.1E-06
Gadd DA 35945220 ADIPOQ protein levels (SeqId = 3554-24) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 0.47 2.1E-06
Gadd DA 35945220 COL11A2 protein levels (SeqId = 11278-4) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 0.47 2.2E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Pain (Self-report) Whole blood Basic model 18413 cg07661704 chr4:139144433 SLC7A11 0.13 2.2E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg07109838 chr4:139106603 SLC7A11 0.047 2.2E-06
Vallerga CL 32144264 Parkinson's disease DNA methylation Whole blood Meta analysis using MOMENT model from OSCA 2131 cg06690548 chr4:139162808 SLC7A11 0.92 2.3E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg07661704 chr4:139144433 SLC7A11 0.056 2.3E-06
Gadd DA 35945220 PRG2 protein levels (SeqId = 7258-5) DNA methylation Whole blood SomaScan protein measurement 774 cg13903162 chr4:139163019 SLC7A11 -0.76 2.3E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg02734904 chr4:139145210 SLC7A11 0.039 2.4E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.039 2.4E-06
Gadd DA 35945220 FTL protein levels (SeqId = 15324-58) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.47 2.4E-06
Gadd DA 35945220 LYPD1 protein levels (SeqId = 9327-3) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.469 2.4E-06
Colicino E 32697766 All cause mortality DNA methylation Whole blood basic model 12300 cg06690548 chr4:139162808 SLC7A11 0.93 2.5E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 -0.0388557 2.5E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.039 2.5E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0410249 2.6E-06
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts 5647 cg07661704 chr4:139144433 SLC7A11 0.011 2.6E-06
Gadd DA 35945220 PTPN2 protein levels (SeqId = 3401-8) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.47 2.6E-06
Sikdar S 31536415 DNA methylation Prenatal smoke exposure Cord blood, whole blood Inverse varience-weighted fixed-effects meta-analysis 5648 cg07661704 chr4:139144433 SLC7A11 0.011 2.6E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg13903162 chr4:139163019 SLC7A11 0.039 2.6E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 0.039 2.7E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.039 2.8E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.039 2.8E-06
Battram T None DNA methylation Free cholesterol to total lipids ratio in large HDL Whole blood None 678 cg06690548 chr4:139162808 SLC7A11 0.16 2.9E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg04487857 chr4:139096540 SLC7A11 -0.0385961 2.9E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.039 3E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0411147 3E-06
Gadd DA 35945220 TK1 protein levels (SeqId = 4301-58) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.47 3E-06
Gadd DA 35945220 FTH1 protein levels (SeqId = 5934-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.47 3E-06
Battram T None DNA methylation Ratio of polyunsaturated fatty acids to total fatty acids Whole blood None 671 cg06690548 chr4:139162808 SLC7A11 0.059 3E-06
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0396365 3.1E-06
Gadd DA 35945220 MASP1 protein levels (SeqId = 9125-23) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.46 3.1E-06
Gadd DA 35945220 IL12B protein levels (SeqId = 10365-132) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.464 3.1E-06
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood discovery 17908 cg13903162 chr4:139163019 SLC7A11 -0.149535 3.2E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg04474257 chr4:139147773 SLC7A11 0.038 3.2E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 -0.0436674 3.3E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 -0.0383803 3.3E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg00534274 chr4:139163341 SLC7A11 -0.015 3.4E-06
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Replication 1955 cg06690548 chr4:139162808 SLC7A11 -0.0077073 3.7E-06
Gadd DA 35945220 KRT1 protein levels (SeqId = 9931-20) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.46 3.7E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg07661704 chr4:139144433 SLC7A11 -0.0374578 3.8E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.038 3.9E-06
Gadd DA 35945220 SPINK14 protein levels (SeqId = 8587-21) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.46 4E-06
Gadd DA 35945220 NGRN protein levels (SeqId = 7153-66) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.46 4.2E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.041 4.3E-06
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 3 14671 cg07661704 chr4:139144433 SLC7A11 -0.0384014 4.4E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg07661704 chr4:139144433 SLC7A11 0.058 4.4E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 0.038 4.5E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 -0.0378473 4.5E-06
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 -0.0378404 4.5E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 0.038 4.6E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 -0.0377871 4.7E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg00534274 chr4:139163341 SLC7A11 0.038 4.8E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 0.038 4.9E-06
Gadd DA 35945220 MAD2L1 protein levels (SeqId = 15313-28) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.45 5E-06
Gadd DA 35945220 SOD3 protein levels (SeqId = 5660-51) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 0.45 5E-06
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0387738 5.3E-06
Jiantao Ma 30796027 DNA methylation hepatic fat whole blood Replication 1904 cg06690548 chr4:139162808 SLC7A11 NA 5.3E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg13028471 chr4:139163535 SLC7A11 -0.0375661 5.3E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0385867 5.7E-06
Mendelson MM 28095459 DNA methylation Body mass index Whole blood Lothian Birth Cohort 1936 920 cg06690548 chr4:139162808 SLC7A11 -0.0181 5.7E-06
Gadd DA 35945220 CLN5 protein levels (SeqId = 8874-53) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.45 5.8E-06
Gadd DA 35945220 NFASC protein levels (SeqId = 7179-69) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.45 5.8E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 0.041 5.8E-06
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0386218 5.8E-06
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0379461 5.8E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.037 5.9E-06
Gadd DA 35945220 ZNF275 protein levels (SeqId = 9609-25) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.45 5.9E-06
Gadd DA 35945220 PSAT1 protein levels (SeqId = 18342-2) DNA methylation Whole blood SomaScan protein measurement 774 cg13903162 chr4:139163019 SLC7A11 -0.73 6E-06
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0373427 6.1E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.037 6.1E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 0.037 6.2E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.037 6.2E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg04487857 chr4:139096540 SLC7A11 -0.0360259 6.2E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 -0.037287 6.3E-06
Gadd DA 35945220 GIP protein levels (SeqId = 5755-29) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.45 6.6E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 0.042 6.7E-06
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg05726013 chr4:139156827 SLC7A11 -0.037141 6.8E-06
Gadd DA 35945220 ADH1C protein levels (SeqId = 15525-294) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.45 6.9E-06
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg24869834 chr4:139146513 SLC7A11 0.013 6.9E-06
Gadd DA 35945220 CYB5A protein levels (SeqId = 11287-14) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.447 7.1E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.037 7.1E-06
Lin H 28067321 DNA methylation Atrial fibrillation Whole blood - 2639 cg06690548 chr4:139162808 SLC7A11 -0.018 7.2E-06
Gadd DA 35945220 CPM protein levels (SeqId = 9416-77) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.45 7.3E-06
Gadd DA 35945220 TNMD protein levels (SeqId = 6578-29) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.45 7.4E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.0369886 7.4E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 0.038 7.4E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg11788572 chr4:139111673 SLC7A11 -0.0611922 7.5E-06
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 0.037 7.7E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg05371417 chr4:139113574 SLC7A11 -0.122773 7.8E-06
Battram T None DNA methylation Waist circumference Whole blood None 717 cg06690548 chr4:139162808 SLC7A11 -0.0123 7.9E-06
Gadd DA 35945220 ALDOC protein levels (SeqId = 9876-20) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.444 8.3E-06
Sharp G 33517419 DNA methylation Maternal body mass index Cord blood Adjusted for paternal BMI using cord blood 4894 cg00534274 chr4:139163341 SLC7A11 -0.00361 8.4E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 -0.0367381 8.5E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.037 8.6E-06
Gadd DA 35945220 F9 protein levels (SeqId = 5307-12) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.44 8.7E-06
Gadd DA 35945220 PTCHD3 protein levels (SeqId = 13517-3) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.44 8.8E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg04474257 chr4:139147773 SLC7A11 0.037 8.9E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 0.037 8.9E-06
Gadd DA 35945220 VAT1 protein levels (SeqId = 18175-65) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.442 8.9E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 -0.0366574 8.9E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg04487857 chr4:139096540 SLC7A11 0.19 9.1E-06
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 3 14671 cg11788572 chr4:139111673 SLC7A11 0.061 9.2E-06
Gadd DA 35945220 LRRC15 protein levels (SeqId = 6557-50) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 0.44 9.2E-06
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.037 9.2E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg13903162 chr4:139163019 SLC7A11 0.038 9.4E-06
Gadd DA 35945220 KLRK1 protein levels (SeqId = 14095-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.44 9.4E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 0.037 9.4E-06
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 -0.0365547 9.5E-06
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0377171 9.6E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg02102889 chr4:139164723 SLC7A11 -0.042901 1E-05
Gadd DA 35945220 MGAT4B protein levels (SeqId = 7141-21) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.439 1E-05
Gadd DA 35945220 CRYZL1 protein levels (SeqId = 9207-60) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.44 1E-05
Gadd DA 35945220 CXCL10 protein levels (SeqId = 4141-79) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.44 1E-05
Gadd DA 35945220 GCH1 protein levels (SeqId = 11185-145) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.44 1E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 -0.0364169 1E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0364067 1E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg13903162 chr4:139163019 SLC7A11 -0.0362123 1E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 -0.0363992 1E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 -0.0363787 1E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 -0.0363296 1.1E-05
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0362994 1.1E-05
Gadd DA 35945220 BMP1 protein levels (SeqId = 3348-49) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.44 1.1E-05
Gadd DA 35945220 COX4I2 protein levels (SeqId = 7850-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.44 1.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Fully-adjusted model 14391 cg06690548 chr4:139162808 SLC7A11 -0.05 1.1E-05
Gadd DA 35945220 GLYAT protein levels (SeqId = 19506-6) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.44 1.1E-05
Cardenas A 31300640 DNA methylation fractional exhaled nitric oxide (FeNO) nasal epithelium None 517 cg13903162 chr4:139163019 SLC7A11 -2.59 1.1E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 -0.0362505 1.1E-05
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns 5647 cg07661704 chr4:139144433 SLC7A11 0.011 1.1E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg04487857 chr4:139096540 SLC7A11 -0.0364237 1.2E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.036 1.2E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0360794 1.2E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg13903162 chr4:139163019 SLC7A11 -0.152658 1.3E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0365283 1.3E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 3 14671 cg13903162 chr4:139163019 SLC7A11 -0.0370282 1.3E-05
Battram T None DNA methylation Ratio of omega 6 fatty acids to total fatty acids Whole blood None 671 cg06690548 chr4:139162808 SLC7A11 0.059 1.3E-05
Gadd DA 35945220 IFNLR1 protein levels (SeqId = 7192-37) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.3E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg05371417 chr4:139113574 SLC7A11 -0.0407829 1.3E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg11788572 chr4:139111673 SLC7A11 0.059 1.4E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.037 1.4E-05
Gadd DA 35945220 NXPH3 protein levels (SeqId = 6054-6) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.4E-05
Gadd DA 35945220 UGT1A6 protein levels (SeqId = 7891-45) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.4E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Kidney Disease (Estimated) Whole blood Basic model 18318 cg13903162 chr4:139163019 SLC7A11 -0.048 1.4E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.036 1.5E-05
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg06690548 chr4:139162808 SLC7A11 0.001 1.5E-05
Gadd DA 35945220 SORD protein levels (SeqId = 15447-45) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.5E-05
Gadd DA 35945220 FCN3 protein levels (SeqId = 5462-62) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.5E-05
Huang D 32520614 DNA methylation Systolic Blood Pressure Whole blood Discovery 4820 cg06690548 chr4:139162808 SLC7A11 NA 1.5E-05
Gadd DA 35945220 CD72 protein levels (SeqId = 7009-8) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.5E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 0.036 1.5E-05
Gadd DA 35945220 SAT2 protein levels (SeqId = 12524-18) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.6E-05
Gadd DA 35945220 APOA1 protein levels (SeqId = 2750-3) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.6E-05
Gadd DA 35945220 NEU1 protein levels (SeqId = 15426-5) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.429 1.6E-05
Gadd DA 35945220 SCARB2 protein levels (SeqId = 5100-53) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.6E-05
Cronjé HT 31910897 DNA methylation Alcohol consumption Whole blood None 108 cg06690548 chr4:139162808 SLC7A11 -0.00082 1.6E-05
Gadd DA 35945220 INSL5 protein levels (SeqId = 10462-14) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.6E-05
Gadd DA 35945220 SWAP70 protein levels (SeqId = 13552-7) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.6E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg11788572 chr4:139111673 SLC7A11 0.13 1.7E-05
Gadd DA 35945220 KLHL13 protein levels (SeqId = 12463-7) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.7E-05
Gadd DA 35945220 SSR1 protein levels (SeqId = 8106-15) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.7E-05
Gadd DA 35945220 KRT1 protein levels (SeqId = 9931-20) DNA methylation Whole blood SomaScan protein measurement 774 cg13903162 chr4:139163019 SLC7A11 -0.69 1.7E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.035 1.7E-05
Gadd DA 35945220 CST8 protein levels (SeqId = 10572-65) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.8E-05
Gadd DA 35945220 MBL2 protein levels (SeqId = 3000-66) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 0.43 1.8E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 -0.0353291 1.9E-05
Gadd DA 35945220 HRK protein levels (SeqId = 8008-28) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 1.9E-05
Gadd DA 35945220 TFIP11 protein levels (SeqId = 9043-7) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.43 1.9E-05
Gadd DA 35945220 MEOX2 protein levels (SeqId = 18259-15) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 1.9E-05
Gadd DA 35945220 F9 protein levels (SeqId = 4876-32) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 1.9E-05
Gadd DA 35945220 CST7 protein levels (SeqId = 3302-58) DNA methylation Whole blood SomaScan protein measurement 774 cg02102889 chr4:139164723 SLC7A11 0.61 2E-05
Gadd DA 35945220 ECE1 protein levels (SeqId = 8767-44) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2E-05
Gadd DA 35945220 ADH1A protein levels (SeqId = 17396-23) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg07661704 chr4:139144433 SLC7A11 0.033 2E-05
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.035149 2.1E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg24869834 chr4:139146513 SLC7A11 0.13 2.1E-05
Gadd DA 35945220 APOL3 protein levels (SeqId = 16823-75) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.1E-05
Anna Ulrich 38184627 DNA methylation Idiopathic/heritable pulmonary arterial hypertension whole blood Discovery 1655 cg06690548 chr4:139162808 SLC7A11 -17.0 2.1E-05
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Discovery 645 cg06690548 chr4:139162808 SLC7A11 -0.033 2.1E-05
Gadd DA 35945220 GHR protein levels (SeqId = 2948-58) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.1E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0358847 2.1E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg04474257 chr4:139147773 SLC7A11 0.035 2.2E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.038 2.2E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg00534274 chr4:139163341 SLC7A11 -0.0841271 2.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg06690548 chr4:139162808 SLC7A11 0.00055 2.3E-05
Gadd DA 35945220 STAP1 protein levels (SeqId = 12510-3) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.3E-05
Gadd DA 35945220 PRKCG protein levels (SeqId = 5476-66) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.3E-05
Mamtani M 26798409 Liability function of hypertriglyceridemic waist DNA methylation Peripheral blood - 850 cg06690548 chr4:139162808 SLC7A11 0.23 2.3E-05
Gadd DA 35945220 CPB1 protein levels (SeqId = 15375-49) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.3E-05
Gadd DA 35945220 NPIPB3 protein levels (SeqId = 9954-2) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg24869834 chr4:139146513 SLC7A11 -0.0012 2.3E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH36 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 -0.0349104 2.3E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg11788572 chr4:139111673 SLC7A11 -0.0576938 2.4E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg00534274 chr4:139163341 SLC7A11 -0.0842512 2.4E-05
Gadd DA 35945220 MLL2 protein levels (SeqId = 13623-4) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.4E-05
Gadd DA 35945220 IL36B protein levels (SeqId = 14149-9) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.4E-05
Gadd DA 35945220 KRT5 protein levels (SeqId = 11177-16) DNA methylation Whole blood SomaScan protein measurement 774 cg13903162 chr4:139163019 SLC7A11 -0.68 2.4E-05
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 0.035 2.4E-05
Huang D 32520614 DNA methylation Diastolic Blood Pressure Whole blood Discovery 4820 cg06690548 chr4:139162808 SLC7A11 NA 2.5E-05
Gadd DA 35945220 LMAN2 protein levels (SeqId = 7638-30) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.5E-05
Battram T None DNA methylation Total cholesterol to total lipids ratio in large HDL Whole blood None 678 cg06690548 chr4:139162808 SLC7A11 0.042 2.5E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.036 2.6E-05
Gadd DA 35945220 ARTN protein levels (SeqId = 2939-10) DNA methylation Whole blood SomaScan protein measurement 774 cg02102889 chr4:139164723 SLC7A11 0.61 2.6E-05
Gadd DA 35945220 RELT protein levels (SeqId = 14112-40) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.6E-05
Battram T None DNA methylation Cholesterol esters to total lipids ratio in large HDL Whole blood None 677 cg06690548 chr4:139162808 SLC7A11 0.059 2.6E-05
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0352211 2.6E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 -0.0346669 2.7E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 -0.0346556 2.7E-05
Gadd DA 35945220 CFB protein levels (SeqId = 4129-72) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.7E-05
Gadd DA 35945220 TFPI protein levels (SeqId = 3336-50) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.7E-05
Gadd DA 35945220 DAG1 protein levels (SeqId = 8369-102) DNA methylation Whole blood SomaScan protein measurement 774 cg13903162 chr4:139163019 SLC7A11 -0.68 2.7E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.035 2.8E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.037 2.8E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.035 2.8E-05
Battram T None DNA methylation Triglycerides in small HDL Whole blood None 682 cg06690548 chr4:139162808 SLC7A11 -10.7 2.8E-05
Gadd DA 35945220 DAO protein levels (SeqId = 19120-33) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.8E-05
Gadd DA 35945220 BCAR3 protein levels (SeqId = 12634-79) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.8E-05
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0345733 2.8E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg04487857 chr4:139096540 SLC7A11 0.17 2.8E-05
Battram T None DNA methylation Monounsaturated fatty acids 16:1 18:1 Whole blood None 667 cg06690548 chr4:139162808 SLC7A11 -0.207 2.9E-05
Gadd DA 35945220 PLCG1 protein levels (SeqId = 4563-61) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.9E-05
Gadd DA 35945220 NCR3 protein levels (SeqId = 3003-29) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.9E-05
Gadd DA 35945220 PRG3 protein levels (SeqId = 9015-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.9E-05
Gadd DA 35945220 LGALS4 protein levels (SeqId = 2982-82) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 2.9E-05
Josephine Robertson 41361833 DNA methylation P01009 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.035 2.9E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.034 3E-05
Battram T None DNA methylation Ratio of monounsaturated fatty acids to total fatty acids Whole blood None 669 cg06690548 chr4:139162808 SLC7A11 -0.053 3E-05
Gadd DA 35945220 PTPRH protein levels (SeqId = 11988-24) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 3E-05
Gadd DA 35945220 ADI1 protein levels (SeqId = 12457-10) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 3E-05
Gadd DA 35945220 ITGB5 protein levels (SeqId = 7755-37) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 3E-05
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 2 14671 cg11788572 chr4:139111673 SLC7A11 0.057 3.1E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 -0.0344089 3.1E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 -0.0344006 3.1E-05
Gadd DA 35945220 POR protein levels (SeqId = 2731-29) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.42 3.1E-05
Gadd DA 35945220 CENPV protein levels (SeqId = 8817-29) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.1E-05
Gadd DA 35945220 TNFSF14 protein levels (SeqId = 5988-49) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.415 3.1E-05
Gadd DA 35945220 SUFU protein levels (SeqId = 17468-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.1E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg07109838 chr4:139106603 SLC7A11 0.042 3.1E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 0.035 3.2E-05
Battram T None DNA methylation Body mass index Whole blood None 714 cg06690548 chr4:139162808 SLC7A11 -0.029 3.2E-05
Gadd DA 35945220 PUF60 protein levels (SeqId = 10575-31) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.2E-05
Gadd DA 35945220 GPD1 protein levels (SeqId = 13697-51) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.2E-05
Gadd DA 35945220 CHEK1 protein levels (SeqId = 2853-68) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.2E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 -0.034282 3.3E-05
Gadd DA 35945220 TNFRSF6B protein levels (SeqId = 5070-76) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.413 3.3E-05
Gadd DA 35945220 BLNK protein levels (SeqId = 19225-11) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.3E-05
Battram T None DNA methylation Total cholesterol to total lipids ratio in medium HDL Whole blood None 682 cg06690548 chr4:139162808 SLC7A11 0.073 3.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg13903162 chr4:139163019 SLC7A11 -0.041 3.3E-05
Gadd DA 35945220 TMCC3 protein levels (SeqId = 8922-4) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.4E-05
Gadd DA 35945220 FCRL3 protein levels (SeqId = 4440-15) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.4E-05
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 -0.0370507 3.4E-05
Gadd DA 35945220 GLTPD2 protein levels (SeqId = 7948-129) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.5E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg05371417 chr4:139113574 SLC7A11 0.034 3.6E-05
Gadd DA 35945220 ADH1B protein levels (SeqId = 9834-62) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.6E-05
Gadd DA 35945220 PKDCC protein levels (SeqId = 8664-36) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.6E-05
Gadd DA 35945220 KLRC3 protein levels (SeqId = 7795-14) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.6E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg00534274 chr4:139163341 SLC7A11 -0.0343686 3.7E-05
Battram T None DNA methylation Triglycerides in medium HDL Whole blood None 683 cg06690548 chr4:139162808 SLC7A11 -10.4 3.7E-05
Battram T None DNA methylation Triglycerides to total lipids ratio in small LDL Whole blood None 676 cg06690548 chr4:139162808 SLC7A11 -0.086 3.7E-05
Gadd DA 35945220 HAPLN4 protein levels (SeqId = 6455-52) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.7E-05
Gadd DA 35945220 GNGT2 protein levels (SeqId = 10917-40) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.7E-05
Gadd DA 35945220 PALM protein levels (SeqId = 18306-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.7E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0340483 3.7E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.0340369 3.7E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg00534274 chr4:139163341 SLC7A11 -0.0340766 3.7E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg07661704 chr4:139144433 SLC7A11 -0.0344 3.8E-05
Gadd DA 35945220 MACROD1 protein levels (SeqId = 13653-335) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.8E-05
Gadd DA 35945220 SLC35G2 protein levels (SeqId = 13501-10) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.8E-05
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg15441006 chr4:139110589 SLC7A11 NA 3.8E-05
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.035 3.8E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 0.034 3.9E-05
Battram T None DNA methylation Glycoprotein acetyls Whole blood None 683 cg06690548 chr4:139162808 SLC7A11 -0.93 3.9E-05
Gadd DA 35945220 BRPF1 protein levels (SeqId = 11671-19) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 3.9E-05
Gadd DA 35945220 AKR1C4 protein levels (SeqId = 18397-5) DNA methylation Whole blood SomaScan protein measurement 774 cg13903162 chr4:139163019 SLC7A11 -0.66 3.9E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.034 3.9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Osteoarthritis Whole blood Basic model 16114 cg04474257 chr4:139147773 SLC7A11 0.05 4E-05
Gadd DA 35945220 BDP1 protein levels (SeqId = 8929-7) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4E-05
Gadd DA 35945220 C8A protein levels (SeqId = 2429-27) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4E-05
Gadd DA 35945220 ASIC4 protein levels (SeqId = 6951-26) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.409 4E-05
Gadd DA 35945220 ADAMTS15 protein levels (SeqId = 4533-76) DNA methylation Whole blood SomaScan protein measurement 774 cg02102889 chr4:139164723 SLC7A11 0.59 4.1E-05
Gadd DA 35945220 AGR2 protein levels (SeqId = 4959-2) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.1E-05
Gadd DA 35945220 TERF1 protein levels (SeqId = 10049-112) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.408 4.1E-05
Gadd DA 35945220 PROL1 protein levels (SeqId = 6530-63) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.1E-05
Gadd DA 35945220 UGDH protein levels (SeqId = 17755-5) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.408 4.2E-05
Gadd DA 35945220 CREB3L2 protein levels (SeqId = 17336-54) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.2E-05
Gadd DA 35945220 PPIB protein levels (SeqId = 4718-5) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.3E-05
Gadd DA 35945220 PYCR2 protein levels (SeqId = 18328-36) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.3E-05
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 -0.0337317 4.4E-05
Gadd DA 35945220 ADAM10 protein levels (SeqId = 8654-13) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.4E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 4 14671 cg06690548 chr4:139162808 SLC7A11 0.036 4.5E-05
Gadd DA 35945220 GUSB protein levels (SeqId = 15562-24) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.5E-05
Gadd DA 35945220 RCL protein levels (SeqId = 17785-11) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.5E-05
Gadd DA 35945220 WFDC5 protein levels (SeqId = 6969-14) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 4.5E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg24869834 chr4:139146513 SLC7A11 0.04 4.6E-05
Gadd DA 35945220 IQCF1 protein levels (SeqId = 7991-54) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.6E-05
Gadd DA 35945220 ADAMTSL2 protein levels (SeqId = 6379-62) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 4.6E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.0340195 4.7E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.035 4.7E-05
Gadd DA 35945220 RBM23 protein levels (SeqId = 11590-5) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.7E-05
Gadd DA 35945220 OSCAR protein levels (SeqId = 7116-31) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.41 4.7E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg11788572 chr4:139111673 SLC7A11 -0.0546985 4.7E-05
Gadd DA 35945220 GLP1R protein levels (SeqId = 13085-18) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 4.8E-05
Gadd DA 35945220 AGAP3 protein levels (SeqId = 13960-15) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 4.8E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 0.034 4.9E-05
Gadd DA 35945220 GAL protein levels (SeqId = 15390-3) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 4.9E-05
Gadd DA 35945220 SPINK4 protein levels (SeqId = 19213-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 4.9E-05
Battram T None DNA methylation Cholesterol esters in large VLDL Whole blood None 661 cg06690548 chr4:139162808 SLC7A11 -8.7 5E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.034 5E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 0.033 5.1E-05
Gadd DA 35945220 GJD2 protein levels (SeqId = 11678-105) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.1E-05
Gadd DA 35945220 RERG protein levels (SeqId = 17822-57) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.1E-05
Gadd DA 35945220 SERPIND1 protein levels (SeqId = 3316-58) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.1E-05
Gadd DA 35945220 RAPGEF5 protein levels (SeqId = 9059-14) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.2E-05
Gadd DA 35945220 CBX5 protein levels (SeqId = 4540-11) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.2E-05
Gadd DA 35945220 ACVR2B protein levels (SeqId = 9412-52) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.2E-05
Gadd DA 35945220 SMEK1 protein levels (SeqId = 10866-60) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.2E-05
Gadd DA 35945220 SPAST protein levels (SeqId = 8388-24) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.2E-05
Gadd DA 35945220 CTRB2 protein levels (SeqId = 5648-28) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.3E-05
Gadd DA 35945220 SLCO5A1 protein levels (SeqId = 11669-39) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.3E-05
Gadd DA 35945220 FUT9 protein levels (SeqId = 6991-24) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.3E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg07109838 chr4:139106603 SLC7A11 -1.3 5.3E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 -0.0333441 5.4E-05
Gadd DA 35945220 CTRB1 protein levels (SeqId = 5671-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.4E-05
Gadd DA 35945220 GDNF protein levels (SeqId = 5822-22) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.4E-05
Gadd DA 35945220 EDF1 protein levels (SeqId = 12415-122) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.4E-05
Gadd DA 35945220 GNMT protein levels (SeqId = 14006-36) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.4E-05
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0333251 5.4E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg00534274 chr4:139163341 SLC7A11 0.033 5.4E-05
Gadd DA 35945220 LECT2 protein levels (SeqId = 16763-11) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.401 5.5E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 0.033 5.6E-05
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0337292 5.6E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg11788572 chr4:139111673 SLC7A11 0.13 5.7E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg09021112 chr4:139164790 SLC7A11 0.033 5.7E-05
Gadd DA 35945220 MAD1L1 protein levels (SeqId = 13618-15) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.7E-05
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0341585 5.7E-05
Gadd DA 35945220 UBC protein levels (SeqId = 6647-55) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.8E-05
Gadd DA 35945220 RGS3 protein levels (SeqId = 12827-37) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.8E-05
Gadd DA 35945220 F3 protein levels (SeqId = 4931-59) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.8E-05
Battram T None DNA methylation Ribs bone mineral density Whole blood None 702 cg06690548 chr4:139162808 SLC7A11 -1.92 5.8E-05
Gadd DA 35945220 UBE2A protein levels (SeqId = 17743-14) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.8E-05
Gadd DA 35945220 EVA1C protein levels (SeqId = 8877-22) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 5.8E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 -0.0331733 5.8E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 0.033 5.9E-05
Gadd DA 35945220 RARRES2 protein levels (SeqId = 3079-62) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6E-05
Gadd DA 35945220 CRIM1 protein levels (SeqId = 15492-1) DNA methylation Whole blood SomaScan protein measurement 774 cg07109838 chr4:139106603 SLC7A11 0.73 6E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 3 14671 cg13903162 chr4:139163019 SLC7A11 -0.0342688 6.1E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.034 6.1E-05
Gadd DA 35945220 CARD17 protein levels (SeqId = 18267-74) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.2E-05
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0330384 6.3E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 0.033 6.3E-05
Gadd DA 35945220 CARD18 protein levels (SeqId = 18190-15) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.4E-05
Gadd DA 35945220 DCAF5 protein levels (SeqId = 11283-13) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.4E-05
Gadd DA 35945220 ARMC5 protein levels (SeqId = 8785-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.4E-05
Gadd DA 35945220 UBE2G2 protein levels (SeqId = 9199-6) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.4E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg11788572 chr4:139111673 SLC7A11 0.058 6.4E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 2 14671 cg06690548 chr4:139162808 SLC7A11 -0.0333501 6.5E-05
Gadd DA 35945220 GALE protein levels (SeqId = 11457-53) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.5E-05
Battram T None DNA methylation Serum total triglycerides Whole blood None 676 cg06690548 chr4:139162808 SLC7A11 -0.31 6.5E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg02102889 chr4:139164723 SLC7A11 0.11 6.5E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg02734904 chr4:139145210 SLC7A11 -0.0329337 6.6E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg21877274 chr4:139107328 SLC7A11 0.033 6.7E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg07661704 chr4:139144433 SLC7A11 -0.033379 6.7E-05
Battram T 27886173 DNA methylation Ulcerative colitis Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640 163 cg00534274 chr4:139163341 SLC7A11 0.035 6.7E-05
Gadd DA 35945220 PILRA protein levels (SeqId = 8825-4) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.7E-05
Gadd DA 35945220 FGF17 protein levels (SeqId = 3494-71) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.8E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Liver Cirrhosis Whole blood Basic model 18325 cg06690548 chr4:139162808 SLC7A11 -0.0058 6.8E-05
Gadd DA 35945220 RNF128 protein levels (SeqId = 8633-18) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.8E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Fully-adjusted model 13971 cg07661704 chr4:139144433 SLC7A11 0.022 6.8E-05
Gadd DA 35945220 CSDC2 protein levels (SeqId = 12754-14) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.9E-05
Battram T None DNA methylation Cholesterol esters to total lipids ratio in medium HDL Whole blood None 683 cg06690548 chr4:139162808 SLC7A11 0.07 6.9E-05
Gadd DA 35945220 CLPSL2 protein levels (SeqId = 7767-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 6.9E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0337187 7.1E-05
Gadd DA 35945220 GULP1 protein levels (SeqId = 19180-38) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.3E-05
Gadd DA 35945220 NPPB protein levels (SeqId = 16751-15) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.3E-05
Gadd DA 35945220 GDF3 protein levels (SeqId = 16755-195) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.4 7.3E-05
Gadd DA 35945220 PNLIPRP1 protein levels (SeqId = 6627-25) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.3E-05
Gadd DA 35945220 RNPC3 protein levels (SeqId = 12814-17) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.395 7.3E-05
Gadd DA 35945220 CHI3L1 protein levels (SeqId = 11104-13) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.4E-05
Gadd DA 35945220 BDH2 protein levels (SeqId = 17329-2) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.4E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg04474257 chr4:139147773 SLC7A11 -0.0327101 7.4E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 4 14671 cg07661704 chr4:139144433 SLC7A11 -0.0385627 7.4E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg04487857 chr4:139096540 SLC7A11 0.17 7.5E-05
Jia T 31811260 Thalamus volume DNA methylation Whole blood None 3337 cg06690548 chr4:139162808 SLC7A11 NA 7.5E-05
Gadd DA 35945220 IL17C protein levels (SeqId = 9255-5) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.5E-05
Wilson LE 30938765 DNA methylation Alcohol Consumption Whole blood replication 187 cg06690548 chr4:139162808 SLC7A11 NA 7.5E-05
Gadd DA 35945220 AFM protein levels (SeqId = 4763-31) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.6E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg13903162 chr4:139163019 SLC7A11 -0.0328722 7.7E-05
Gadd DA 35945220 STMN4 protein levels (SeqId = 6267-51) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.393 7.7E-05
Gadd DA 35945220 FGF1 protein levels (SeqId = 3486-58) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.7E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 -0.0334864 7.8E-05
Gadd DA 35945220 GALNT1 protein levels (SeqId = 7090-17) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.8E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Fully-adjusted model 14076 cg06690548 chr4:139162808 SLC7A11 -0.016 7.9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Ischemic Heart Disease Whole blood Basic model 17483 cg06690548 chr4:139162808 SLC7A11 -0.017 7.9E-05
Gadd DA 35945220 SLPI protein levels (SeqId = 4413-3) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.9E-05
Gadd DA 35945220 ERLIN1 protein levels (SeqId = 8776-10) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 7.9E-05
Canouil M 34116986 DNA methylation Gestational diabetes mellitus cord blood EWAS in offspring 536 cg05726013 chr4:139156827 SLC7A11 -0.191 7.9E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0325804 7.9E-05
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg02734904 chr4:139145210 SLC7A11 0.033 7.9E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg13028471 chr4:139163535 SLC7A11 0.033 8E-05
Gadd DA 35945220 KNG1 protein levels (SeqId = 7784-1) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8E-05
Gadd DA 35945220 CFAP45 protein levels (SeqId = 6553-68) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.1E-05
Gadd DA 35945220 MYNN protein levels (SeqId = 12455-48) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.1E-05
Gadd DA 35945220 SLC26A5 protein levels (SeqId = 9127-4) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.1E-05
Gadd DA 35945220 RB1 protein levels (SeqId = 5024-67) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.2E-05
Gadd DA 35945220 MICB protein levels (SeqId = 5102-55) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.2E-05
Gadd DA 35945220 TLL1 protein levels (SeqId = 6383-90) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.2E-05
Gadd DA 35945220 COL10A1 protein levels (SeqId = 15653-9) DNA methylation Whole blood SomaScan protein measurement 774 cg07109838 chr4:139106603 SLC7A11 0.71 8.2E-05
Battram T None DNA methylation Triglycerides to total lipids ratio in medium HDL Whole blood None 683 cg06690548 chr4:139162808 SLC7A11 -0.107 8.4E-05
Gadd DA 35945220 ERBB3 protein levels (SeqId = 2617-56) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.4E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg02102889 chr4:139164723 SLC7A11 0.032 8.4E-05
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0333004 8.5E-05
Anna Ulrich 38184627 DNA methylation Idiopathic/heritable pulmonary arterial hypertension whole blood Discovery 1655 cg07661704 chr4:139144433 SLC7A11 9.4 8.6E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.032627 8.7E-05
Gadd DA 35945220 ZNF566 protein levels (SeqId = 12795-2) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.7E-05
Gadd DA 35945220 PFDN1 protein levels (SeqId = 19242-21) DNA methylation Whole blood SomaScan protein measurement 774 cg13903162 chr4:139163019 SLC7A11 -0.63 8.7E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1V2 whole blood OSCA model 1 14671 cg06690548 chr4:139162808 SLC7A11 -0.0323776 8.8E-05
Gadd DA 35945220 IFNA16 protein levels (SeqId = 6421-52) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.8E-05
Gadd DA 35945220 UGP2 protein levels (SeqId = 13939-14) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.8E-05
Gadd DA 35945220 MARCO protein levels (SeqId = 9003-99) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.8E-05
Gadd DA 35945220 TXNIP protein levels (SeqId = 11682-7) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.8E-05
Gadd DA 35945220 ADAMTS15 protein levels (SeqId = 4533-76) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.8E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg11788572 chr4:139111673 SLC7A11 -0.0323622 8.8E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 0.032 8.8E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg11788572 chr4:139111673 SLC7A11 0.054 8.9E-05
Gadd DA 35945220 HSPA1A protein levels (SeqId = 4124-24) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.9E-05
Gadd DA 35945220 CD14 protein levels (SeqId = 8969-49) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.9E-05
Gadd DA 35945220 LGI3 protein levels (SeqId = 8003-57) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 8.9E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg07661704 chr4:139144433 SLC7A11 -0.0323436 8.9E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg13903162 chr4:139163019 SLC7A11 -1.1 9E-05
Gadd DA 35945220 FAH protein levels (SeqId = 11424-4) DNA methylation Whole blood SomaScan protein measurement 774 cg13903162 chr4:139163019 SLC7A11 -0.63 9E-05
Gadd DA 35945220 ZNF843 protein levels (SeqId = 8321-27) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.1E-05
Gadd DA 35945220 ARFGAP1 protein levels (SeqId = 11556-19) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.1E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg13903162 chr4:139163019 SLC7A11 0.033 9.1E-05
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 4 14671 cg13903162 chr4:139163019 SLC7A11 -0.0368985 9.2E-05
Gadd DA 35945220 ZNF415 protein levels (SeqId = 12811-55) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.2E-05
Gadd DA 35945220 KIAA1644 protein levels (SeqId = 10432-3) DNA methylation Whole blood SomaScan protein measurement 774 cg07109838 chr4:139106603 SLC7A11 0.71 9.3E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg07109838 chr4:139106603 SLC7A11 0.032 9.3E-05
Gadd DA 35945220 SUV420H2 protein levels (SeqId = 12452-32) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.4E-05
Gadd DA 35945220 RNF24 protein levels (SeqId = 9583-17) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.4E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg13903162 chr4:139163019 SLC7A11 -0.032232 9.4E-05
Gadd DA 35945220 SYTL1 protein levels (SeqId = 12892-10) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.5E-05
Battram T None DNA methylation Trunk tissue mass Whole blood None 699 cg06690548 chr4:139162808 SLC7A11 -1.7e-05 9.5E-05
Gadd DA 35945220 MTMR1 protein levels (SeqId = 11167-6) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.5E-05
Gadd DA 35945220 BMPR2 protein levels (SeqId = 4862-63) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.5E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 0.033 9.5E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg02734904 chr4:139145210 SLC7A11 0.032 9.6E-05
Gadd DA 35945220 BPI protein levels (SeqId = 4126-22) DNA methylation Whole blood SomaScan protein measurement 774 cg02102889 chr4:139164723 SLC7A11 0.56 9.6E-05
Gadd DA 35945220 IL31RA protein levels (SeqId = 8273-84) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.6E-05
Gadd DA 35945220 KCNN1 protein levels (SeqId = 13539-131) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.6E-05
Battram T None DNA methylation Trunk total mass Whole blood None 699 cg06690548 chr4:139162808 SLC7A11 -1.7e-05 9.6E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg06690548 chr4:139162808 SLC7A11 -0.0300438 9.8E-05
Gadd DA 35945220 IL27 protein levels (SeqId = 2829-19) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.388 9.8E-05
Gadd DA 35945220 COL3A1 protein levels (SeqId = 18880-81) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.8E-05
Gadd DA 35945220 POTEG protein levels (SeqId = 7960-53) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.8E-05
Battram T None DNA methylation Android fat mass Whole blood None 706 cg06690548 chr4:139162808 SLC7A11 -0.00011 9.8E-05
Gadd DA 35945220 IGFBP2 protein levels (SeqId = 8469-41) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 0.39 9.8E-05
Gadd DA 35945220 KYNU protein levels (SeqId = 4559-64) DNA methylation Whole blood SomaScan protein measurement 774 cg06690548 chr4:139162808 SLC7A11 -0.39 9.8E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg07661704 chr4:139144433 SLC7A11 -0.0316756 9.8E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg24869834 chr4:139146513 SLC7A11 0.032 9.9E-05

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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