EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for SMPD3

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg00891541 chr16:68481487 SMPD3 0.0046 0E+00
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg00891541 chr16:68481487 SMPD3 0.052 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg01041405 chr16:68440620 SMPD3 -0.0021 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg02593381 chr16:68434111 SMPD3 -0.003 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg03873826 chr16:68407311 SMPD3 0.012 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg04464276 chr16:68481049 SMPD3 0.0035 0E+00
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg05144928 chr16:68481543 SMPD3 0.037 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg05591728 chr16:68477022 SMPD3 -0.0021 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg05948940 chr16:68481342 SMPD3 0.0023 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg06106242 chr16:68482941 SMPD3 0.0032 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg06106242 chr16:68482941 SMPD3 -0.011 0E+00
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg06106242 chr16:68482941 SMPD3 -0.019 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg07461772 chr16:68482809 SMPD3 0.0021 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08890345 chr16:68481248 SMPD3 0.0019 0E+00
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg08890345 chr16:68481248 SMPD3 0.028 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg10426893 chr16:68482821 SMPD3 0.0023 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg10556064 chr16:68481489 SMPD3 0.0029 0E+00
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg10556064 chr16:68481489 SMPD3 0.044 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg12136772 chr16:68481813 SMPD3 0.0013 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg17217677 chr16:68483194 SMPD3 0.0025 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg17217677 chr16:68483194 SMPD3 -0.012 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg19297232 chr16:68483021 SMPD3 0.0063 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg19297232 chr16:68483021 SMPD3 -0.029 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg22116290 chr16:68481968 SMPD3 0.0012 0E+00
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg23758485 chr16:68482202 SMPD3 -0.0055 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg07461772 chr16:68482809 SMPD3 0.0017 3.6E-207
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg08371223 chr16:68443138 SMPD3 0.45 1.6E-147
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg05948940 chr16:68481342 SMPD3 0.0024 2.7E-134
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg02593381 chr16:68434111 SMPD3 -0.25531 1.8E-128
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg26899718 chr16:68404797 SMPD3 -0.24255 1.5E-127
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg03599928 chr16:68405168 SMPD3 -0.18213 5.3E-118
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg04464276 chr16:68481049 SMPD3 0.16 3.8E-109
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg07735969 chr16:68418473 SMPD3 -0.17141 3.5E-106
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg04685738 chr16:68421884 SMPD3 0.15 8.3E-104
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg00891541 chr16:68481487 SMPD3 0.24 1.5E-88
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg05948940 chr16:68481342 SMPD3 0.13 4.4E-87
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg10556064 chr16:68481489 SMPD3 0.19 3.5E-81
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg07554664 chr16:68431982 SMPD3 0.1 2.1E-77
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg12136772 chr16:68481813 SMPD3 0.13 4.3E-76
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.15 1.7E-74
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg06106242 chr16:68482941 SMPD3 0.11 1.9E-65
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg08890345 chr16:68481248 SMPD3 0.1 9.3E-64
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.14 2E-63
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg05392527 chr16:68394825 SMPD3 0.071 3.8E-58
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.131136 2.8E-57
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg10422047 chr16:68401557 SMPD3 0.059 4.7E-57
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg01041405 chr16:68440620 SMPD3 0.097 4.5E-56
Shah S 25249537 DNA methylation Sex Whole blood Discovery 815 cg23758485 chr16:68482202 SMPD3 NA 1E-50
Shah S 25249537 DNA methylation Sex Whole blood Replication 445 cg23758485 chr16:68482202 SMPD3 NA 1E-50
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg22116290 chr16:68481968 SMPD3 0.061 1.5E-48
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.12 3.8E-47
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg01210622 chr16:68405731 SMPD3 0.05 1.1E-45
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.12 3.6E-45
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg15201635 chr16:68482637 SMPD3 -0.03656 3.2E-44
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19297232 chr16:68483021 SMPD3 0.13 3.5E-43
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.11 7.2E-43
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 3666146 (gene symbol: SLC7A6) Whole blood Meta-analysis 4170 cg02226672 chr16:68398533 SMPD3 NA 3.9E-42
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.111917 4.1E-42
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg00891541 chr16:68481487 SMPD3 NA 7.3E-41
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg05591728 chr16:68477022 SMPD3 NA 7.3E-41
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg17217677 chr16:68483194 SMPD3 0.083 1.3E-40
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.11 2.9E-38
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg02226672 chr16:68398533 SMPD3 0.12 3.5E-38
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.11 1.3E-37
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg10556064 chr16:68481489 SMPD3 NA 2.2E-35
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.1 5.1E-35
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg07461772 chr16:68482809 SMPD3 0.0039 2.1E-34
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg04464276 chr16:68481049 SMPD3 NA 3.2E-34
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.099 2.3E-33
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg16658734 chr16:68401882 SMPD3 0.039 3.5E-33
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg22116290 chr16:68481968 SMPD3 0.0014 3.6E-32
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg08694014 chr16:68482591 SMPD3 -0.01524 4.2E-32
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.097 4.6E-32
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.097 6.9E-32
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0963197 1.4E-31
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0948945 1.1E-30
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.094 6.2E-30
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.093 1.6E-29
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg05144928 chr16:68481543 SMPD3 0.082 2.2E-28
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg26899718 chr16:68404797 SMPD3 4.0 4.9E-27
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.087 3.4E-26
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.086 1.5E-25
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg08937732 chr16:68393121 SMPD3 0.00029 1.7E-25
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg26899718 chr16:68404797 SMPD3 -0.57791 1.9E-25
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg24921262 chr16:68404979 SMPD3 4.2 1.4E-24
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 -0.0839295 2.4E-24
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg09578614 chr16:68405406 SMPD3 0.011 7.7E-24
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.083 1.1E-23
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg26899718 chr16:68404797 SMPD3 0.56 7.3E-23
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg04464276 chr16:68481049 SMPD3 0.0016 1.4E-22
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg05948940 chr16:68481342 SMPD3 NA 1.7E-22
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.08 4.2E-22
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.079 9.1E-22
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.078 2.1E-21
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.078 4.2E-21
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.075 6.4E-20
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.075 1.2E-19
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.074 2.4E-19
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0735492 4.7E-19
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.073 7.3E-19
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.073 1E-18
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.073 1.1E-18
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg05948940 chr16:68481342 SMPD3 0.0052 1.9E-18
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0722358 1.9E-18
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0717172 3.4E-18
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg00891541 chr16:68481487 SMPD3 NA 6.2E-18
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg10556064 chr16:68481489 SMPD3 NA 7.8E-18
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.070474 1.3E-17
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg24921262 chr16:68404979 SMPD3 0.48 1.4E-17
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg24921262 chr16:68404979 SMPD3 0.48 1.8E-17
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg26899718 chr16:68404797 SMPD3 0.49 2.3E-17
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.069 3.6E-17
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0691866 4.9E-17
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg01041405 chr16:68440620 SMPD3 0.0012 8.1E-17
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.069 9.2E-17
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg26899718 chr16:68404797 SMPD3 0.47 1.3E-16
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0679013 1.8E-16
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.067824 2E-16
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 3666282 (gene symbol: ZFP90) Whole blood Meta-analysis 4170 cg10426893 chr16:68482821 SMPD3 NA 3.2E-16
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.067233 3.6E-16
Bozack 34569420 DNA methylation Infant sex Umbilical artery Umbilical artery 229 cg23758485 chr16:68482202 SMPD3 NA 4.1E-16
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.066 8.3E-16
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0711914 1E-15
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg07461772 chr16:68482809 SMPD3 -0.004 1.1E-15
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg26906642 chr16:68394729 SMPD3 0.021 1.4E-15
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0654509 2.1E-15
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg09578614 chr16:68405406 SMPD3 -0.00022 2.2E-15
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0650291 3.2E-15
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.065 3.5E-15
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.065 4.6E-15
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.064 1E-14
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg07554664 chr16:68431982 SMPD3 -0.0011 1.2E-14
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg07461772 chr16:68482809 SMPD3 0.026 1.8E-14
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 0.067 3.1E-14
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.062 4.9E-14
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg10426893 chr16:68482821 SMPD3 0.0012 5.2E-14
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0619169 6.1E-14
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.062 6.4E-14
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 0.066 1.3E-13
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0658833 1.3E-13
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 0.079 1.4E-13
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.061 1.8E-13
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.061 1.8E-13
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0606365 2E-13
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0606181 2E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg03873826 chr16:68407311 SMPD3 -0.0012 2.1E-13
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg24921262 chr16:68404979 SMPD3 0.41 3.1E-13
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0601062 3.2E-13
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg08371223 chr16:68443138 SMPD3 0.0033 3.3E-13
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg23758485 chr16:68482202 SMPD3 NA 3.4E-13
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.06 3.5E-13
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.06 4.7E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg03599928 chr16:68405168 SMPD3 -0.0013 1E-12
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg00891541 chr16:68481487 SMPD3 -0.012 1.2E-12
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0586092 1.2E-12
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.058 1.4E-12
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg19297232 chr16:68483021 SMPD3 -0.027 1.4E-12
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.058 1.5E-12
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0582673 1.6E-12
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.058 1.9E-12
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.058 1.9E-12
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0578927 2.3E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 0.075 2.3E-12
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg27045405 chr16:68409791 SMPD3 0.017 2.6E-12
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.058 2.7E-12
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0620327 2.9E-12
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0575398 3.1E-12
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.057 4.4E-12
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0570948 4.5E-12
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg05948940 chr16:68481342 SMPD3 NA 6.4E-12
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg05392527 chr16:68394825 SMPD3 -0.0565716 7E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.056 1.1E-11
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Replication 5704 cg07461772 chr16:68482809 SMPD3 NA 1.2E-11
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.056 1.2E-11
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg07405419 chr16:68451677 SMPD3 0.056 1.3E-11
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.056 1.5E-11
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg15201635 chr16:68482637 SMPD3 0.00039 1.5E-11
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.055 1.8E-11
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg05392527 chr16:68394825 SMPD3 -0.0554519 1.8E-11
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg24921262 chr16:68404979 SMPD3 -0.0598816 1.9E-11
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg08489197 chr16:68423179 SMPD3 0.055 2E-11
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.055 2.1E-11
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg17217677 chr16:68483194 SMPD3 -0.012 2.7E-11
Kyung WK 32795589 DNA methylation atopy nasal polyp discovery 108 cg02226672 chr16:68398533 SMPD3 -0.051 2.8E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg07405419 chr16:68451677 SMPD3 -0.0620536 3E-11
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg07735969 chr16:68418473 SMPD3 -0.0574329 3.4E-11
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0589991 3.5E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.054 4.3E-11
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg02845545 chr16:68408904 SMPD3 -2.4 4.4E-11
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0541868 5.1E-11
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg10422047 chr16:68401557 SMPD3 -0.00083 5.2E-11
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.054 6E-11
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg24411294 chr16:68406165 SMPD3 -0.0629002 6.9E-11
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.054 7.4E-11
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg07735969 chr16:68418473 SMPD3 2.3 8.7E-11
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 0.069 9.6E-11
Yousefi P 26553366 DNA methylation Sex Cord Blood - 111 cg23758485 chr16:68482202 SMPD3 0.65 1.1E-10
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0531853 1.1E-10
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg16658734 chr16:68401882 SMPD3 0.29 1.2E-10
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.053 1.4E-10
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.052 2.3E-10
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.052 2.3E-10
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg02845545 chr16:68408904 SMPD3 -0.0725517 2.5E-10
Johnson KC 28693600 DNA methylation Age Breast - 100 cg08694014 chr16:68482591 SMPD3 0.012 2.6E-10
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0520669 2.8E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 -0.0674776 2.9E-10
Bozack 34569420 DNA methylation Infant sex Umbilical artery Umbilical artery 229 cg10556064 chr16:68481489 SMPD3 NA 3E-10
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg07405419 chr16:68451677 SMPD3 -0.190362 3.4E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg10426893 chr16:68482821 SMPD3 -0.0056 3.7E-10
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 -0.0514046 4.7E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg05591728 chr16:68477022 SMPD3 0.0012 5.5E-10
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg07405419 chr16:68451677 SMPD3 -2.1 5.5E-10
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 0.066 6E-10
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg08371223 chr16:68443138 SMPD3 -0.0510735 6E-10
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.051 6.9E-10
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg07735969 chr16:68418473 SMPD3 -0.389688 1.1E-09
Battram T 29383109 DNA methylation Age Breast EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE101961 121 cg15201635 chr16:68482637 SMPD3 0.00085 1.1E-09
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.05 1.2E-09
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0500179 1.3E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.05 1.4E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg04747382 chr16:68406461 SMPD3 0.00059 1.4E-09
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg16658734 chr16:68401882 SMPD3 -0.262138 1.5E-09
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 0.054 1.6E-09
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0497767 1.6E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg26899718 chr16:68404797 SMPD3 0.07 1.8E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg02226672 chr16:68398533 SMPD3 -0.0094 2.1E-09
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.049 2.3E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg05948940 chr16:68481342 SMPD3 -0.0490899 2.7E-09
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg01210622 chr16:68405731 SMPD3 -0.20629 2.8E-09
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg07405419 chr16:68451677 SMPD3 -0.180502 2.9E-09
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.049 3.2E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg05144928 chr16:68481543 SMPD3 0.0023 3.2E-09
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg05392527 chr16:68394825 SMPD3 -0.021 3.3E-09
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg06335316 chr16:68412522 SMPD3 0.049 3.6E-09
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg07405419 chr16:68451677 SMPD3 -0.258883 4E-09
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0485497 4E-09
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg08371223 chr16:68443138 SMPD3 -0.0484397 4.4E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg04464276 chr16:68481049 SMPD3 -0.048431 4.4E-09
Knijnenburg 30833390 DNA methylation very early preterm birth (<28 weeks) whole blood discovery 784 cg02226672 chr16:68398533 SMPD3 0.33 4.5E-09
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0483625 4.6E-09
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0483417 4.7E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg07405419 chr16:68451677 SMPD3 0.048 4.9E-09
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg07735969 chr16:68418473 SMPD3 2.1 5E-09
Bozack 34569420 DNA methylation Infant sex Umbilical artery Umbilical artery 229 cg00891541 chr16:68481487 SMPD3 NA 5.4E-09
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg07461772 chr16:68482809 SMPD3 -0.0489819 5.9E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg04464276 chr16:68481049 SMPD3 0.006 6E-09
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0479249 6.3E-09
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0478452 6.7E-09
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg24921262 chr16:68404979 SMPD3 -0.0493068 7E-09
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg03517653 chr16:68433648 SMPD3 -0.0476717 7.6E-09
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.047596 8E-09
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0475498 8.3E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 0.061 8.5E-09
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg08371223 chr16:68443138 SMPD3 -0.01041 8.6E-09
Reynolds LM 25404168 DNA methylation Age T cells T cells 227 cg05948940 chr16:68481342 SMPD3 NA 9.9E-09
Bozack 34569420 DNA methylation Infant sex cord blood Cord blood 179 cg10556064 chr16:68481489 SMPD3 NA 9.9E-09
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.047 1.1E-08
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg05948940 chr16:68481342 SMPD3 0.0071 1.2E-08
Yang BZ 23332324 DNA methylation Child abuse Saliva - 192 cg09202227 chr16:68482715 SMPD3 NA 1.2E-08
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg24921262 chr16:68404979 SMPD3 -0.0495532 1.3E-08
Liu C 27843151 DNA methylation Alcohol consumption per day Whole blood European ancestry 9643 cg07735969 chr16:68418473 SMPD3 -0.00010962 1.4E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg24921262 chr16:68404979 SMPD3 0.05 1.4E-08
Koestler DC 23868178 DNA methylation Right vs left colon adenomas Colon adenoma Basic model 135 cg01041405 chr16:68440620 SMPD3 0.66 1.4E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg07405419 chr16:68451677 SMPD3 -0.0533921 1.4E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0467379 1.5E-08
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg24921262 chr16:68404979 SMPD3 0.42 1.5E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg26899718 chr16:68404797 SMPD3 0.056 1.6E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0466056 1.6E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.047 1.6E-08
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.046 1.9E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg02845545 chr16:68408904 SMPD3 -0.283357 1.9E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 -0.046289 2E-08
Yusuf N 28835163 Ratio of inflammatory biomarker post- to pre-fenofibrate treatment DNA methylation CD4+ T-cells Inflammatory biomarker is c-reactive protein 750 cg05591728 chr16:68477022 SMPD3 -47.0 2.1E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg03599928 chr16:68405168 SMPD3 0.31 2.1E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg26899718 chr16:68404797 SMPD3 0.059 2.2E-08
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.046 2.3E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg24921262 chr16:68404979 SMPD3 0.41 2.4E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg07735969 chr16:68418473 SMPD3 -0.0630065 2.4E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg02165227 chr16:68450100 SMPD3 -0.227769 2.4E-08
Imgenberg-Kreuz J 26857698 DNA methylation Primary Sjogrens syndrome Whole blood Whole blood 500 cg26899718 chr16:68404797 SMPD3 NA 2.5E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg04464276 chr16:68481049 SMPD3 -0.006 2.7E-08
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0458106 2.8E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.046 2.9E-08
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg03599928 chr16:68405168 SMPD3 0.004 2.9E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg07405419 chr16:68451677 SMPD3 -0.242307 3E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg24411294 chr16:68406165 SMPD3 -0.0533792 3E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.046 3E-08
Darina Czamara 38600394 DNA methylation sex placenta meta-analysis of robust linear regression results per cohort 746 cg23758485 chr16:68482202 SMPD3 0.16 3.2E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg25226249 chr16:68451778 SMPD3 0.21 3.3E-08
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg07735969 chr16:68418473 SMPD3 0.048 3.4E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg07735969 chr16:68418473 SMPD3 -0.045734 3.4E-08
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0455318 3.4E-08
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg02593381 chr16:68434111 SMPD3 0.046 3.5E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg15201635 chr16:68482637 SMPD3 0.00039 3.5E-08
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.045 3.6E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg07405419 chr16:68451677 SMPD3 0.16 3.7E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Stroke Whole blood Basic model 18023 cg26899718 chr16:68404797 SMPD3 0.053 3.8E-08
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg04464276 chr16:68481049 SMPD3 0.0084 4.1E-08
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Lifetime consumption discovery 5606 cg07461772 chr16:68482809 SMPD3 NA 4.1E-08
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.045 4.2E-08
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.045 4.6E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg01210622 chr16:68405731 SMPD3 0.001 4.7E-08
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.045 5.1E-08
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0449169 5.2E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 -0.0448582 5.5E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg18580455 chr16:68415443 SMPD3 0.045 5.5E-08
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.044781 5.8E-08
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.045 5.8E-08
Bozack 34569420 DNA methylation Infant sex cord blood Cord blood 179 cg00891541 chr16:68481487 SMPD3 NA 6E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 0.048 6.1E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg07405419 chr16:68451677 SMPD3 0.051 6.3E-08
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg07735969 chr16:68418473 SMPD3 0.00038 6.3E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg26906642 chr16:68394729 SMPD3 0.0012 6.4E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg26899718 chr16:68404797 SMPD3 0.057 6.5E-08
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg03599928 chr16:68405168 SMPD3 2.1 6.8E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg07461772 chr16:68482809 SMPD3 0.044 7.1E-08
Bozack 34569420 DNA methylation Infant sex cord blood Cord blood 179 cg23758485 chr16:68482202 SMPD3 NA 7.2E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.044 7.2E-08
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 -0.0443524 7.7E-08
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg16658734 chr16:68401882 SMPD3 0.24 7.8E-08
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.044314 7.9E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg19854171 chr16:68478620 SMPD3 0.044 8.6E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg12136772 chr16:68481813 SMPD3 0.0052 9E-08
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 -0.0440922 9.2E-08
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg07735969 chr16:68418473 SMPD3 -0.00393 1E-07
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg05948940 chr16:68481342 SMPD3 0.54 1.1E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg02226672 chr16:68398533 SMPD3 0.008 1.1E-07
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.044 1.2E-07
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0436508 1.2E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg24411294 chr16:68406165 SMPD3 -0.265768 1.3E-07
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg07461772 chr16:68482809 SMPD3 -0.0444592 1.3E-07
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0435208 1.3E-07
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 -0.0434438 1.4E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.043 1.4E-07
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0434001 1.4E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 0.056 1.5E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0433218 1.5E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0432972 1.6E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg25114671 chr16:68445232 SMPD3 -0.207775 1.6E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 -0.0431473 1.7E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg07405419 chr16:68451677 SMPD3 -0.0479423 1.8E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0430614 1.8E-07
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0429538 1.9E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg02845545 chr16:68408904 SMPD3 -0.0596347 2E-07
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous decade consumption discovery 5606 cg07461772 chr16:68482809 SMPD3 NA 2.1E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg10556064 chr16:68481489 SMPD3 -0.0068 2.1E-07
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 -0.0556568 2.1E-07
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0428229 2.1E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 -0.0556816 2.1E-07
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg07735969 chr16:68418473 SMPD3 -0.0039 2.2E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg04464276 chr16:68481049 SMPD3 0.043 2.4E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg16812566 chr16:68464675 SMPD3 0.35 2.6E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg01041405 chr16:68440620 SMPD3 0.042 2.8E-07
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg16658734 chr16:68401882 SMPD3 0.23 2.9E-07
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg12136772 chr16:68481813 SMPD3 0.0082 2.9E-07
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.042 2.9E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 -0.0550154 2.9E-07
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 -0.0422008 3.2E-07
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0421957 3.2E-07
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg02226672 chr16:68398533 SMPD3 1.7 3.3E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.042 3.4E-07
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0420711 3.4E-07
Mulder RH 33450751 DNA methylation sex Whole blood Discovery 2338 cg03599928 chr16:68405168 SMPD3 0.009 3.5E-07
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0452763 3.6E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg05144928 chr16:68481543 SMPD3 0.0014 3.7E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg08371223 chr16:68443138 SMPD3 -0.0418958 3.8E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg24921262 chr16:68404979 SMPD3 -0.280429 3.9E-07
Christiansen C 33593402 DNA methylation Smoking Whole blood Current vs never smoking meta-analysis in European samples 912 cg07461772 chr16:68482809 SMPD3 NA 3.9E-07
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg06067989 chr16:68396359 SMPD3 -0.0447601 4E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.042 4.2E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 -0.041699 4.4E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg02165227 chr16:68450100 SMPD3 -0.0416918 4.4E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.041681 4.4E-07
Battram T 29383109 DNA methylation Age Breast EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE101961 121 cg08694014 chr16:68482591 SMPD3 0.00042 5E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg18580455 chr16:68415443 SMPD3 0.041 5.2E-07
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg07461772 chr16:68482809 SMPD3 -0.0413721 5.4E-07
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg07461772 chr16:68482809 SMPD3 NA 5.4E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg07461772 chr16:68482809 SMPD3 -0.018 5.4E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg02845545 chr16:68408904 SMPD3 0.057 5.7E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg07405419 chr16:68451677 SMPD3 -0.0468631 5.9E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg06067989 chr16:68396359 SMPD3 0.044 6.1E-07
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 2 14671 cg02845545 chr16:68408904 SMPD3 0.057 6.2E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg12136772 chr16:68481813 SMPD3 -0.0411193 6.3E-07
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg07554664 chr16:68431982 SMPD3 1.2 6.6E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.041 7.3E-07
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.041 7.5E-07
Battram T 30291105 DNA methylation Age Colon, rectum EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE113904 232 cg07735969 chr16:68418473 SMPD3 -0.00144 7.6E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg02593381 chr16:68434111 SMPD3 -0.0407685 7.8E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 2 14671 cg07405419 chr16:68451677 SMPD3 -0.0465306 8E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0407127 8.1E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg27045405 chr16:68409791 SMPD3 -0.00064 8.3E-07
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg06067989 chr16:68396359 SMPD3 -0.0435967 8.4E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg06335316 chr16:68412522 SMPD3 -0.0406375 8.5E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg07735969 chr16:68418473 SMPD3 -0.0406352 8.5E-07
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.04 9.3E-07
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg08890345 chr16:68481248 SMPD3 NA 9.7E-07
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0404233 9.7E-07
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0404018 9.8E-07
Bohlin J 27717397 DNA methylation Gestational age Cord blood Ultrasound-estimated gestational age 1068 cg03599928 chr16:68405168 SMPD3 -0.00036701 1.1E-06
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg06106242 chr16:68482941 SMPD3 NA 1.2E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg25226249 chr16:68451778 SMPD3 -0.039 1.2E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg02165227 chr16:68450100 SMPD3 -0.0400438 1.2E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 4 14671 cg07405419 chr16:68451677 SMPD3 0.066 1.3E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg00891541 chr16:68481487 SMPD3 0.0019 1.3E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg02543668 chr16:68430491 SMPD3 -1.9 1.3E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg07405419 chr16:68451677 SMPD3 -0.026 1.3E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 3 14671 cg07405419 chr16:68451677 SMPD3 -0.0456599 1.4E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0398688 1.4E-06
Singmann P 26500701 DNA methylation Sex Whole blood Meta-analysis 1999 cg23758485 chr16:68482202 SMPD3 NA 1.4E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.039773 1.4E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg01041405 chr16:68440620 SMPD3 0.0036 1.5E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0395956 1.6E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.04 1.6E-06
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 -0.0395479 1.7E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg07735969 chr16:68418473 SMPD3 0.041 1.7E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.039 1.8E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.039 1.8E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0394242 1.8E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg07735969 chr16:68418473 SMPD3 0.041 1.8E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0424469 1.9E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg03599928 chr16:68405168 SMPD3 0.26 1.9E-06
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg03599928 chr16:68405168 SMPD3 0.26 1.9E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg08489197 chr16:68423179 SMPD3 0.039 1.9E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg07461772 chr16:68482809 SMPD3 -0.0392639 2E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg07405419 chr16:68451677 SMPD3 0.045 2E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 -0.0510863 2E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0422615 2E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0391317 2.1E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 -0.0391088 2.2E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0390862 2.2E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg05392527 chr16:68394825 SMPD3 -0.0390776 2.2E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg22116290 chr16:68481968 SMPD3 0.0037 2.2E-06
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.039 2.2E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg02226672 chr16:68398533 SMPD3 -0.0768569 2.3E-06
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.039 2.3E-06
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 1 14671 cg03517653 chr16:68433648 SMPD3 -0.0390145 2.3E-06
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.039 2.3E-06
Cardenas A 31300640 DNA methylation fractional exhaled nitric oxide (FeNO) nasal epithelium None 517 cg26899718 chr16:68404797 SMPD3 -2.08 2.3E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Pain (Self-report) Whole blood Basic model 18413 cg24921262 chr16:68404979 SMPD3 0.28 2.3E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg05948940 chr16:68481342 SMPD3 0.089 2.3E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.039 2.4E-06
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.039 2.4E-06
Dunn E 30905381 DNA methylation Maternal Psychopathology Leukocytes Adversity was experienced between ages 8 months and 6 years old 774 cg08937732 chr16:68393121 SMPD3 NA 2.4E-06
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg17217677 chr16:68483194 SMPD3 0.0045 2.4E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg02226672 chr16:68398533 SMPD3 -0.0648136 2.4E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg19854171 chr16:68478620 SMPD3 0.039 2.6E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0388012 2.6E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 -0.0387563 2.7E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0417916 2.7E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg26496071 chr16:68447904 SMPD3 -0.178931 2.8E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg02226672 chr16:68398533 SMPD3 0.0011 2.8E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg24921262 chr16:68404979 SMPD3 0.046 2.8E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 -0.05034 2.8E-06
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0386477 2.8E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg12136772 chr16:68481813 SMPD3 -0.0386265 2.9E-06
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg24921262 chr16:68404979 SMPD3 -0.0416994 3E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg24411294 chr16:68406165 SMPD3 0.045 3E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg24921262 chr16:68404979 SMPD3 0.054 3.1E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg02226672 chr16:68398533 SMPD3 -0.064276 3.2E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 1 14671 cg03517653 chr16:68433648 SMPD3 -0.0384294 3.2E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg17217677 chr16:68483194 SMPD3 -0.193201 3.2E-06
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg19297232 chr16:68483021 SMPD3 0.0086 3.3E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0383717 3.3E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg27045405 chr16:68409791 SMPD3 -0.186248 3.3E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 -0.0383376 3.4E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0383345 3.4E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 3 14671 cg24921262 chr16:68404979 SMPD3 -0.0402299 3.4E-06
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 3 14671 cg02845545 chr16:68408904 SMPD3 0.053 3.4E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0383014 3.5E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg07735969 chr16:68418473 SMPD3 0.04 3.5E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg07405419 chr16:68451677 SMPD3 -0.0632752 3.6E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg08489197 chr16:68423179 SMPD3 0.038 3.7E-06
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0381651 3.8E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg02845545 chr16:68408904 SMPD3 0.053 3.8E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg05392527 chr16:68394825 SMPD3 -0.0381368 3.8E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg08489197 chr16:68423179 SMPD3 0.038 4E-06
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg06335316 chr16:68412522 SMPD3 0.038 4.1E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 3 14671 cg24921262 chr16:68404979 SMPD3 0.038 4.1E-06
Reynolds LM 25404168 DNA methylation Age T cells T cells 227 cg26899718 chr16:68404797 SMPD3 NA 4.1E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 0.038 4.2E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08694014 chr16:68482591 SMPD3 -6.7e-05 4.4E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg04464276 chr16:68481049 SMPD3 0.14 4.6E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.038 4.6E-06
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg04713743 chr16:68406468 SMPD3 -0.00856 4.8E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg23758485 chr16:68482202 SMPD3 0.038 4.8E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg08371223 chr16:68443138 SMPD3 -0.0377379 4.8E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 -0.037713 4.9E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0406746 4.9E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg06067989 chr16:68396359 SMPD3 0.04 5.1E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg07405419 chr16:68451677 SMPD3 -0.0376167 5.2E-06
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0376115 5.2E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.038 5.2E-06
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg02593381 chr16:68434111 SMPD3 -0.037585 5.3E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 -0.0375344 5.4E-06
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.037 5.7E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg02165227 chr16:68450100 SMPD3 -0.0374432 5.7E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg07461772 chr16:68482809 SMPD3 -0.0381522 5.8E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg07735969 chr16:68418473 SMPD3 0.052 5.9E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg04713743 chr16:68406468 SMPD3 -0.00055 5.9E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 0.048 6.3E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg03599928 chr16:68405168 SMPD3 0.052 6.4E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 2 14671 cg06067989 chr16:68396359 SMPD3 -0.039837 6.6E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg16658734 chr16:68401882 SMPD3 1.9 6.9E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg07405419 chr16:68451677 SMPD3 0.19 6.9E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg07461772 chr16:68482809 SMPD3 -0.0375241 6.9E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 3 14671 cg06067989 chr16:68396359 SMPD3 -0.0397748 7E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg26899718 chr16:68404797 SMPD3 -0.0482922 7E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.037 7E-06
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg06067989 chr16:68396359 SMPD3 -0.0397268 7.1E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg03599928 chr16:68405168 SMPD3 -0.0521706 7.1E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.037 7.3E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg26899718 chr16:68404797 SMPD3 0.044 7.3E-06
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg07554664 chr16:68431982 SMPD3 -0.0369915 7.4E-06
Battram T 30291105 DNA methylation Age Colon, rectum EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE113904 232 cg07461772 chr16:68482809 SMPD3 0.0018 7.5E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg07405419 chr16:68451677 SMPD3 -0.028 7.6E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg16812566 chr16:68464675 SMPD3 0.3 7.6E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.036906 7.8E-06
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 3 14671 cg03412735 chr16:68482518 SMPD3 -0.0362969 7.9E-06
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0368414 8.1E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg07405419 chr16:68451677 SMPD3 -0.0416102 8.2E-06
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg03517653 chr16:68433648 SMPD3 -0.0368103 8.2E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0368075 8.2E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg01041405 chr16:68440620 SMPD3 0.037 8.3E-06
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg26899718 chr16:68404797 SMPD3 0.0035 8.4E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.037 8.5E-06
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 4 14671 cg07405419 chr16:68451677 SMPD3 0.063 8.6E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg04464276 chr16:68481049 SMPD3 -0.0366877 8.8E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg26906642 chr16:68394729 SMPD3 -0.176047 9.4E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg07405419 chr16:68451677 SMPD3 -0.0365435 9.5E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0365196 9.7E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg24921262 chr16:68404979 SMPD3 1.9 9.9E-06
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0364686 9.9E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg08890345 chr16:68481248 SMPD3 0.0058 1E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg07461772 chr16:68482809 SMPD3 -0.0364095 1E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg07405419 chr16:68451677 SMPD3 -0.0605188 1E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 2 14671 cg07405419 chr16:68451677 SMPD3 0.041 1E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.036 1.1E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.036 1.1E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 -0.0363199 1.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg04464276 chr16:68481049 SMPD3 0.023 1.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg05676789 chr16:68482144 SMPD3 -0.026 1.1E-05
Gadd DA 35945220 QPCT protein levels (SeqId = 7849-3) DNA methylation Whole blood SomaScan protein measurement 774 cg02165227 chr16:68450100 SMPD3 0.97 1.1E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.036 1.1E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 0.036 1.1E-05
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.036 1.2E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg07735969 chr16:68418473 SMPD3 0.29 1.2E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg02593381 chr16:68434111 SMPD3 -0.0370065 1.2E-05
Johnson KC 28693600 DNA methylation Age Breast - 100 cg15201635 chr16:68482637 SMPD3 0.012 1.3E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg07735969 chr16:68418473 SMPD3 -0.214846 1.3E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg02593381 chr16:68434111 SMPD3 -0.0369088 1.3E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg07461772 chr16:68482809 SMPD3 -0.036003 1.3E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.035994 1.3E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg07405419 chr16:68451677 SMPD3 -0.0359253 1.3E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 4 14671 cg06067989 chr16:68396359 SMPD3 -0.0395886 1.4E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.036 1.4E-05
Anna Ulrich 38184627 DNA methylation Idiopathic/heritable pulmonary arterial hypertension whole blood Discovery 1655 cg07735969 chr16:68418473 SMPD3 26.0 1.4E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 -0.0357743 1.5E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg03517653 chr16:68433648 SMPD3 -0.0356286 1.6E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0383849 1.6E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg07461772 chr16:68482809 SMPD3 -0.035481 1.7E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 0.038 1.7E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg06067989 chr16:68396359 SMPD3 -0.0380649 1.7E-05
Josephine Robertson 41361833 DNA methylation P23142 whole blood OSCA model 2 14671 cg02543668 chr16:68430491 SMPD3 0.037 1.7E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg02845545 chr16:68408904 SMPD3 -0.0491217 1.8E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 -0.035424 1.8E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg07735969 chr16:68418473 SMPD3 0.035 1.8E-05
Gadd DA 35945220 CST1 protein levels (SeqId = 5459-33) DNA methylation Whole blood SomaScan protein measurement 774 cg03873826 chr16:68407311 SMPD3 1.0 1.8E-05
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg04464276 chr16:68481049 SMPD3 NA 1.8E-05
Gadd DA 35945220 HAPLN1 protein levels (SeqId = 3196-6) DNA methylation Whole blood SomaScan protein measurement 774 cg04464276 chr16:68481049 SMPD3 0.65 1.8E-05
Gadd DA 35945220 LIPN protein levels (SeqId = 8097-77) DNA methylation Whole blood SomaScan protein measurement 774 cg04337959 chr16:68406244 SMPD3 0.65 1.8E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg11570753 chr16:68451654 SMPD3 -0.0544443 1.9E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 -0.0352601 1.9E-05
Gadd DA 35945220 ITIH3 protein levels (SeqId = 7145-1) DNA methylation Whole blood SomaScan protein measurement 774 cg07735969 chr16:68418473 SMPD3 1.1 2E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg26899718 chr16:68404797 SMPD3 1.6 2E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg26899718 chr16:68404797 SMPD3 -0.0456307 2E-05
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg26899718 chr16:68404797 SMPD3 0.00038 2E-05
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg03599928 chr16:68405168 SMPD3 NA 2.1E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg04713743 chr16:68406468 SMPD3 0.00072 2.1E-05
Reynolds LM 25404168 DNA methylation Age Monocytes Monocytes 1264 cg05948940 chr16:68481342 SMPD3 NA 2.1E-05
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg10426893 chr16:68482821 SMPD3 0.00021 2.1E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg02543668 chr16:68430491 SMPD3 -0.204636 2.1E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg02226672 chr16:68398533 SMPD3 -0.0588941 2.2E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg26899718 chr16:68404797 SMPD3 0.044 2.2E-05
Gross AM 27105112 DNA methylation HIV infection Neutrophils Neutrophils 60 cg15201635 chr16:68482637 SMPD3 0.15 2.2E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 0.035 2.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg24921262 chr16:68404979 SMPD3 0.12 2.2E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg07461772 chr16:68482809 SMPD3 -0.0357352 2.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg03599928 chr16:68405168 SMPD3 0.041 2.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg08937732 chr16:68393121 SMPD3 0.00092 2.3E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 2 14671 cg02593381 chr16:68434111 SMPD3 0.036 2.3E-05
Hannon E 27572077 DNA methylation Schizophrenia Whole blood Phase 1 675 cg07735969 chr16:68418473 SMPD3 0.01 2.3E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg05687869 chr16:68470638 SMPD3 -0.0349048 2.4E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg04747382 chr16:68406461 SMPD3 0.15 2.5E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg16658734 chr16:68401882 SMPD3 0.035 2.5E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg26899718 chr16:68404797 SMPD3 -0.297381 2.5E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg01210622 chr16:68405731 SMPD3 0.15 2.6E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.035 2.6E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg06067989 chr16:68396359 SMPD3 -0.0372294 2.6E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg07405419 chr16:68451677 SMPD3 -0.0394443 2.8E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg03873826 chr16:68407311 SMPD3 0.035 2.8E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg01210622 chr16:68405731 SMPD3 0.15 2.8E-05
Gadd DA 35945220 FTH1 protein levels (SeqId = 5934-1) DNA methylation Whole blood SomaScan protein measurement 774 cg24921262 chr16:68404979 SMPD3 -1.3 2.8E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0345621 2.8E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg06335316 chr16:68412522 SMPD3 -0.0352847 2.9E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg07461772 chr16:68482809 SMPD3 -0.0343661 2.9E-05
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg03599928 chr16:68405168 SMPD3 0.0041 2.9E-05
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.034479 3E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg07405419 chr16:68451677 SMPD3 0.058 3E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg24411294 chr16:68406165 SMPD3 0.04 3E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 0.034 3.1E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg08371223 chr16:68443138 SMPD3 0.034 3.1E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg08489197 chr16:68423179 SMPD3 -0.0343939 3.1E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg06335316 chr16:68412522 SMPD3 -0.0351348 3.1E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg06335316 chr16:68412522 SMPD3 -0.0343438 3.2E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg07405419 chr16:68451677 SMPD3 0.034 3.2E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg24411294 chr16:68406165 SMPD3 -0.0343151 3.2E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 3 14671 cg02226672 chr16:68398533 SMPD3 -0.0570641 3.2E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0342738 3.3E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 3 14671 cg02845545 chr16:68408904 SMPD3 -0.0477317 3.3E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 0.036 3.3E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg10422047 chr16:68401557 SMPD3 -0.154547 3.4E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 3 14671 cg02593381 chr16:68434111 SMPD3 0.035 3.5E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg02226672 chr16:68398533 SMPD3 -0.0571935 3.6E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg03873826 chr16:68407311 SMPD3 -0.0044 3.6E-05
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg03873826 chr16:68407311 SMPD3 -0.00227 3.6E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg22116290 chr16:68481968 SMPD3 0.0032 3.7E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.034 3.7E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0340259 3.8E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 -0.0340093 3.8E-05
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg02593381 chr16:68434111 SMPD3 NA 3.8E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg02845545 chr16:68408904 SMPD3 0.047 3.9E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0339664 3.9E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 3 14671 cg16812566 chr16:68464675 SMPD3 0.035 3.9E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg18580455 chr16:68415443 SMPD3 0.036 3.9E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 1 14671 cg16812566 chr16:68464675 SMPD3 0.034 4E-05
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg05144928 chr16:68481543 SMPD3 NA 4.1E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg05687869 chr16:68470638 SMPD3 0.034 4.1E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg16812566 chr16:68464675 SMPD3 -0.27084 4.1E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg02845545 chr16:68408904 SMPD3 0.047 4.1E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg25114671 chr16:68445232 SMPD3 0.17 4.1E-05
Gadd DA 35945220 FTL protein levels (SeqId = 15324-58) DNA methylation Whole blood SomaScan protein measurement 774 cg24921262 chr16:68404979 SMPD3 -1.27 4.2E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 3 14671 cg07405419 chr16:68451677 SMPD3 0.039 4.3E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg06067989 chr16:68396359 SMPD3 -0.0337804 4.3E-05
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg26899718 chr16:68404797 SMPD3 -0.0023 4.3E-05
Gadd DA 35945220 KLKB1 protein levels (SeqId = 4152-58) DNA methylation Whole blood SomaScan protein measurement 774 cg27045405 chr16:68409791 SMPD3 -0.9 4.3E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg04747382 chr16:68406461 SMPD3 -0.144101 4.4E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg26899718 chr16:68404797 SMPD3 -0.043593 4.4E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0337013 4.4E-05
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 0.034 4.5E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg18580455 chr16:68415443 SMPD3 0.036 4.5E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg06335316 chr16:68412522 SMPD3 0.034 4.5E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 2 14671 cg02226672 chr16:68398533 SMPD3 -0.0565425 4.5E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg06067989 chr16:68396359 SMPD3 -0.0351598 4.6E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg06067989 chr16:68396359 SMPD3 0.035 4.7E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg04464276 chr16:68481049 SMPD3 -0.0336147 4.7E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg04464276 chr16:68481049 SMPD3 -0.0335898 4.7E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg02845545 chr16:68408904 SMPD3 0.068 4.7E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg07405419 chr16:68451677 SMPD3 -0.0335635 4.8E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg19854171 chr16:68478620 SMPD3 -0.0335314 4.9E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg06067989 chr16:68396359 SMPD3 -0.0359603 4.9E-05
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 1 14671 cg03517653 chr16:68433648 SMPD3 -0.0335162 4.9E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg01041405 chr16:68440620 SMPD3 0.033 5E-05
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 2 14671 cg07405419 chr16:68451677 SMPD3 0.038 5E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg07735969 chr16:68418473 SMPD3 0.27 5E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0334724 5E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg05392527 chr16:68394825 SMPD3 0.037 5E-05
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 2 14671 cg03517653 chr16:68433648 SMPD3 -0.0368638 5.1E-05
Gadd DA 35945220 EPHA1 protein levels (SeqId = 3431-54) DNA methylation Whole blood SomaScan protein measurement 774 cg07461772 chr16:68482809 SMPD3 0.4 5.1E-05
Gadd DA 35945220 QPCT protein levels (SeqId = 7849-3) DNA methylation Whole blood SomaScan protein measurement 774 cg01210622 chr16:68405731 SMPD3 0.73 5.2E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg02165227 chr16:68450100 SMPD3 -0.0333884 5.2E-05
Josephine Robertson 41361833 DNA methylation Q16610 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0333573 5.3E-05
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 1 14671 cg06335316 chr16:68412522 SMPD3 0.033 5.5E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg24411294 chr16:68406165 SMPD3 -0.0388083 5.6E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg03517653 chr16:68433648 SMPD3 -0.0332527 5.6E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg06067989 chr16:68396359 SMPD3 -0.0367817 5.6E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg24411294 chr16:68406165 SMPD3 0.039 5.7E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0332188 5.7E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg03599928 chr16:68405168 SMPD3 -0.216909 5.7E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg03549163 chr16:68397790 SMPD3 -0.0334655 5.8E-05
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg05676789 chr16:68482144 SMPD3 1.0 5.8E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 3 14671 cg07735969 chr16:68418473 SMPD3 0.032 5.9E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg05948940 chr16:68481342 SMPD3 -0.035464 5.9E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 0.036 6E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg05392527 chr16:68394825 SMPD3 0.033 6E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg26899718 chr16:68404797 SMPD3 -0.0410562 6.3E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0330225 6.3E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg24411294 chr16:68406165 SMPD3 0.035 6.4E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 -0.0330021 6.4E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg02593381 chr16:68434111 SMPD3 0.0057 6.4E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg24411294 chr16:68406165 SMPD3 0.039 6.4E-05
Ambatipudi S 26864933 DNA methylation Smoking Peripheral blood Current vs never smoking 721 cg10426893 chr16:68482821 SMPD3 NA 6.4E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg15035774 chr16:68450892 SMPD3 0.033 6.5E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg07461772 chr16:68482809 SMPD3 -0.0323697 6.6E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg08371223 chr16:68443138 SMPD3 0.033 6.6E-05
Gadd DA 35945220 C9 protein levels (SeqId = 3060-43) DNA methylation Whole blood SomaScan protein measurement 774 cg07735969 chr16:68418473 SMPD3 1.0 6.6E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 4 14671 cg02845545 chr16:68408904 SMPD3 -0.0685646 6.6E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg02543668 chr16:68430491 SMPD3 0.034 6.7E-05
Gadd DA 35945220 GSTT1 protein levels (SeqId = 19230-12) DNA methylation Whole blood SomaScan protein measurement 774 cg08694014 chr16:68482591 SMPD3 0.65 6.7E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg02165227 chr16:68450100 SMPD3 0.034 6.7E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg10556064 chr16:68481489 SMPD3 0.0013 6.8E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0328666 6.8E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg02165227 chr16:68450100 SMPD3 0.048 6.9E-05
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.032853 6.9E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 -0.0328268 7E-05
Gadd DA 35945220 PCSK7 protein levels (SeqId = 4459-68) DNA methylation Whole blood SomaScan protein measurement 774 cg08694014 chr16:68482591 SMPD3 0.64 7E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg27045405 chr16:68409791 SMPD3 0.029 7E-05
Liu C 27843151 DNA methylation Alcohol consumption per day CD14+ monocytes CD14+ monocytes 1251 cg02593381 chr16:68434111 SMPD3 -0.000182 7E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 2 14671 cg02845545 chr16:68408904 SMPD3 -0.0455156 7.1E-05
Gross AM 27105112 DNA methylation HIV infection Neutrophils Neutrophils 60 cg07554664 chr16:68431982 SMPD3 0.12 7.1E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg07554664 chr16:68431982 SMPD3 0.033 7.2E-05
Gadd DA 35945220 SLITRK6 protein levels (SeqId = 16916-19) DNA methylation Whole blood SomaScan protein measurement 774 cg19297232 chr16:68483021 SMPD3 0.34 7.2E-05
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg05948940 chr16:68481342 SMPD3 -0.827232 7.2E-05
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg04464276 chr16:68481049 SMPD3 -0.0327553 7.2E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.032744 7.3E-05
Gadd DA 35945220 IGHM protein levels (SeqId = 3069-52) DNA methylation Whole blood SomaScan protein measurement 774 cg04713743 chr16:68406468 SMPD3 0.86 7.3E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg08489197 chr16:68423179 SMPD3 -0.0327338 7.3E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg06067989 chr16:68396359 SMPD3 0.033 7.4E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg07735969 chr16:68418473 SMPD3 0.0034 7.4E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg18580455 chr16:68415443 SMPD3 0.033 7.4E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg08489197 chr16:68423179 SMPD3 -0.0326838 7.5E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 2 14671 cg01041405 chr16:68440620 SMPD3 0.035 7.5E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg03599928 chr16:68405168 SMPD3 -0.0456246 7.5E-05
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg10556064 chr16:68481489 SMPD3 -0.0326773 7.5E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg26899718 chr16:68404797 SMPD3 0.033 7.6E-05
Josephine Robertson 41361833 DNA methylation P22792 whole blood OSCA model 1 14671 cg24921262 chr16:68404979 SMPD3 -0.0326461 7.7E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg26899718 chr16:68404797 SMPD3 -0.0007 7.7E-05
Gadd DA 35945220 SPON1 protein levels (SeqId = 4297-62) DNA methylation Whole blood SomaScan protein measurement 774 cg02165227 chr16:68450100 SMPD3 0.89 7.7E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg02845545 chr16:68408904 SMPD3 -0.0451932 7.8E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg23758485 chr16:68482202 SMPD3 -0.00013 7.8E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg03549163 chr16:68397790 SMPD3 -0.0326882 7.9E-05
Li S 28811542 DNA methylation Age Whole blood - 1366 cg01041405 chr16:68440620 SMPD3 -0.0254 7.9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Fully-adjusted model 13971 cg26899718 chr16:68404797 SMPD3 0.049 7.9E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg07461772 chr16:68482809 SMPD3 -0.0331498 7.9E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg02845545 chr16:68408904 SMPD3 -0.198925 8E-05
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 1 14671 cg03517653 chr16:68433648 SMPD3 -0.0325658 8E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg17217677 chr16:68483194 SMPD3 0.033 8E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg07735969 chr16:68418473 SMPD3 -0.177792 8.1E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg06335316 chr16:68412522 SMPD3 -0.032448 8.1E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0325121 8.2E-05
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0325006 8.2E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg02226672 chr16:68398533 SMPD3 0.032 8.3E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Fully-adjusted model 14391 cg02593381 chr16:68434111 SMPD3 0.11 8.3E-05
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg07735969 chr16:68418473 SMPD3 NA 8.3E-05
Gadd DA 35945220 WFDC2 protein levels (SeqId = 11388-75) DNA methylation Whole blood SomaScan protein measurement 774 cg07735969 chr16:68418473 SMPD3 1.0 8.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg15201635 chr16:68482637 SMPD3 0.0015 8.4E-05
Gadd DA 35945220 PRG3 protein levels (SeqId = 9015-1) DNA methylation Whole blood SomaScan protein measurement 774 cg26899718 chr16:68404797 SMPD3 -1.15 8.4E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 1 14671 cg11570753 chr16:68451654 SMPD3 0.032 8.5E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg16658734 chr16:68401882 SMPD3 0.033 8.5E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg24921262 chr16:68404979 SMPD3 -0.0349827 8.6E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg26899718 chr16:68404797 SMPD3 0.0011 8.7E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg03599928 chr16:68405168 SMPD3 -0.0323637 8.8E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg05687869 chr16:68470638 SMPD3 0.034 9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Liver Cirrhosis Whole blood Basic model 18325 cg07461772 chr16:68482809 SMPD3 -0.0055 9.1E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg04713743 chr16:68406468 SMPD3 0.032 9.3E-05
Battram T None DNA methylation Total cholesterol to total lipids ratio in very large VLDL Whole blood None 627 cg04703197 chr16:68406272 SMPD3 0.01 9.4E-05
Gadd DA 35945220 GZMK protein levels (SeqId = 9545-156) DNA methylation Whole blood SomaScan protein measurement 774 cg02845545 chr16:68408904 SMPD3 -1.0 9.4E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg05430886 chr16:68479922 SMPD3 -0.0322564 9.4E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 2 14671 cg23758485 chr16:68482202 SMPD3 0.032 9.5E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Osteoarthritis Whole blood Basic model 16114 cg03599928 chr16:68405168 SMPD3 0.075 9.5E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg11570753 chr16:68451654 SMPD3 -0.029 9.5E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0322112 9.5E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg12136772 chr16:68481813 SMPD3 0.032 9.7E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg02165227 chr16:68450100 SMPD3 0.032 9.7E-05
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 1 14671 cg02845545 chr16:68408904 SMPD3 -0.0321534 9.8E-05
Bohlin J 27717397 DNA methylation Gestational age Cord blood Ultrasound-estimated gestational age 1068 cg09578614 chr16:68405406 SMPD3 -0.00011043 9.9E-05

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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