EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for SPTLC2

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg14544289 chr14:78051204 SPTLC2 -0.0021 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg19007537 chr14:78082808 SPTLC2 -8.7e-05 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg26362766 chr14:78083524 SPTLC2 -0.00098 0E+00
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg24171453 chr14:78079686 SPTLC2 0.32 3.7E-126
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.173282 2.9E-99
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.16594 4.5E-91
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.153741 2.7E-78
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.151618 3.6E-76
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.145319 4.7E-70
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 ch.14.1182433R chr14:78024853 SPTLC2 NA 1E-69
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.141667 1.2E-66
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.138311 1.4E-63
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.130651 7.2E-57
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.128599 3.9E-55
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.123262 9.1E-51
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.122944 1.6E-50
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.120536 1.3E-48
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.117072 6.1E-46
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg04947514 chr14:78082976 SPTLC2 0.00088 1.8E-44
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.113814 1.7E-43
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.112839 8.8E-43
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.109715 1.6E-40
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.107973 2.7E-39
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.107942 2.8E-39
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.10292 7.6E-36
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg27553433 chr14:78083305 SPTLC2 0.021 1.5E-35
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 ch.14.1182433R chr14:78024853 SPTLC2 0.035 2.4E-35
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg26362766 chr14:78083524 SPTLC2 0.029 7.7E-34
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0995302 1.3E-33
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.097 6.6E-32
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0957556 3.1E-31
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0952645 6.3E-31
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0948667 1.1E-30
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg24171453 chr14:78079686 SPTLC2 -1.54996 5.3E-30
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg08230472 chr14:78083416 SPTLC2 0.00015 8.8E-30
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.0924273 3.3E-29
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.092 6.6E-29
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0880669 1.2E-26
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg26362766 chr14:78083524 SPTLC2 1.5 2.5E-26
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0865523 8.4E-26
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0863011 1.2E-25
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.083985 2.2E-24
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.084 2.6E-24
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0822031 2E-23
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0820603 2.4E-23
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0817912 3.3E-23
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0809089 9.7E-23
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0797997 3.7E-22
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.079737 3.9E-22
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0793075 6.6E-22
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg14544289 chr14:78051204 SPTLC2 -0.00931 9.6E-22
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0772579 7.2E-21
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0769887 9.8E-21
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.076 2.6E-20
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg14544289 chr14:78051204 SPTLC2 0.0021 2.9E-20
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg06175025 chr14:78082992 SPTLC2 0.00045 4.8E-20
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0746141 1.4E-19
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0744459 1.7E-19
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0730536 8E-19
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.073 8.9E-19
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.072 2.5E-18
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 3573152 (gene symbol: SPTLC2) Whole blood Meta-analysis 4170 cg14544289 chr14:78051204 SPTLC2 NA 3E-18
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg14544289 chr14:78051204 SPTLC2 0.028 3.1E-18
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg16213072 chr14:78082735 SPTLC2 0.00014 3.7E-18
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0712945 5.3E-18
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg25532340 chr14:78047326 SPTLC2 -0.043 6.4E-18
Imgenberg-Kreuz J 26857698 DNA methylation Primary Sjogrens syndrome Whole blood Whole blood 500 cg24171453 chr14:78079686 SPTLC2 NA 8E-18
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 -0.0708633 8.4E-18
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0707 1E-17
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0705905 1.1E-17
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.0701483 1.8E-17
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.07 2.3E-17
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg05211862 chr14:78008930 SPTLC2 0.25 2.4E-17
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0698561 2.4E-17
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.07 2.9E-17
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.07 3E-17
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0696379 3.1E-17
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0694451 3.7E-17
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0687203 7.9E-17
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg05211862 chr14:78008930 SPTLC2 -0.082141 1.5E-16
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.068 2.4E-16
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 -0.067245 3.5E-16
Kyung WK 32795589 DNA methylation atopy nasal polyp discovery 108 cg20016490 chr14:78061135 SPTLC2 -0.022 4.2E-16
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0666721 6.3E-16
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg09341423 chr14:78083459 SPTLC2 -0.00046 6.7E-16
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg18569885 chr14:78083170 SPTLC2 0.00047 6.7E-16
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg26685761 chr14:78074371 SPTLC2 0.23 1.3E-15
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg24171453 chr14:78079686 SPTLC2 0.0015 1.3E-15
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.066 1.5E-15
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.065 2E-15
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 0.065 2E-15
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.065 2.3E-15
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.0652185 2.6E-15
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 -0.0651229 2.9E-15
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.065 3.2E-15
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0629501 2.3E-14
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0628966 2.4E-14
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg05211862 chr14:78008930 SPTLC2 -0.0757236 3.3E-14
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.062 4.3E-14
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0622268 4.6E-14
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg15358657 chr14:78082484 SPTLC2 0.013 5.8E-14
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.061922 6.1E-14
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0616796 7.6E-14
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0616029 8.1E-14
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0614905 9E-14
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg25532340 chr14:78047326 SPTLC2 -1.5 9.8E-14
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.061375 1E-13
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.061 1E-13
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0612389 1.1E-13
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0612031 1.2E-13
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg25532340 chr14:78047326 SPTLC2 0.21 1.6E-13
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0607626 1.8E-13
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.0606135 2E-13
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.06 2.6E-13
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 -0.0691104 3.3E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg16213072 chr14:78082735 SPTLC2 -0.00011 3.7E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg04947514 chr14:78082976 SPTLC2 0.00053 4.9E-13
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 0.059 6.7E-13
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.059 7.3E-13
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.0591066 7.8E-13
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.059 7.9E-13
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.059 9.4E-13
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg05211862 chr14:78008930 SPTLC2 -0.071163 9.5E-13
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0588078 1E-12
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.059 1.2E-12
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 0.067 1.5E-12
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.058 1.5E-12
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0582684 1.6E-12
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0581908 1.7E-12
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0581133 1.9E-12
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 0.058 2E-12
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0577856 2.5E-12
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0576078 2.9E-12
Gadd DA 35945220 GSTZ1 protein levels (SeqId = 16872-248) DNA methylation Whole blood SomaScan protein measurement 774 cg03678595 chr14:78023855 SPTLC2 0.28 3.1E-12
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.057 3.7E-12
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0572838 3.8E-12
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0572231 4E-12
Gadd DA 35945220 GSTZ1 protein levels (SeqId = 16872-248) DNA methylation Whole blood SomaScan protein measurement 774 cg14533461 chr14:78021636 SPTLC2 0.53 5.4E-12
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0565969 6.9E-12
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 0.065 7E-12
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg05211862 chr14:78008930 SPTLC2 0.2 7.3E-12
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.057 7.4E-12
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg26685761 chr14:78074371 SPTLC2 0.073 7.6E-12
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.056 9.8E-12
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 0.056 1.2E-11
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.056 1.3E-11
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 ch.14.1182433R chr14:78024853 SPTLC2 0.019 1.5E-11
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.056 1.5E-11
Gadd DA 35945220 GSTZ1 protein levels (SeqId = 16872-248) DNA methylation Whole blood SomaScan protein measurement 774 cg18872420 chr14:78023429 SPTLC2 0.22 1.7E-11
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg24171453 chr14:78079686 SPTLC2 -0.00091654 1.8E-11
Spiers H 25650246 DNA methylation Gestational age Fetal brain - 179 cg24171453 chr14:78079686 SPTLC2 -0.17606 2.2E-11
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0550259 2.6E-11
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.055 2.9E-11
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.055 2.9E-11
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.055 2.9E-11
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0547865 3.1E-11
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg14544289 chr14:78051204 SPTLC2 -0.031 3.4E-11
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 0.055 3.5E-11
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg20016490 chr14:78061135 SPTLC2 -0.054552 3.8E-11
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.054 4E-11
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0543194 4.6E-11
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.054 4.9E-11
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.054 5E-11
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg05211862 chr14:78008930 SPTLC2 -0.0631271 5.2E-11
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.054 5.4E-11
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0537509 7.3E-11
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.0537417 7.3E-11
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.054 8.7E-11
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg26685761 chr14:78074371 SPTLC2 0.19 1.5E-10
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg05211862 chr14:78008930 SPTLC2 -0.0637772 1.5E-10
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg25532340 chr14:78047326 SPTLC2 0.061 1.5E-10
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 -0.0526914 1.7E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 ch.14.1182433R chr14:78024853 SPTLC2 0.00039 1.8E-10
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0525715 1.9E-10
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0514018 4.7E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg20016490 chr14:78061135 SPTLC2 -0.0512906 5.1E-10
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.051 5.7E-10
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 0.051 6.1E-10
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0507398 7.8E-10
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg25532340 chr14:78047326 SPTLC2 0.062 8.3E-10
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg05211862 chr14:78008930 SPTLC2 0.18 9.9E-10
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg26685761 chr14:78074371 SPTLC2 2.8 1.4E-09
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.05 1.5E-09
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0494675 2E-09
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0494504 2.1E-09
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg18872420 chr14:78023429 SPTLC2 -0.022 2.1E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg23187727 chr14:78029584 SPTLC2 0.0012 2.3E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg04947514 chr14:78082976 SPTLC2 0.0021 2.6E-09
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg18872420 chr14:78023429 SPTLC2 -0.08074 2.7E-09
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0488915 3.1E-09
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg14544289 chr14:78051204 SPTLC2 NA 3.2E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.049 3.4E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg18872420 chr14:78023429 SPTLC2 0.0029 3.8E-09
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0485853 3.9E-09
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 0.048 4.9E-09
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.048 5.3E-09
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg26685761 chr14:78074371 SPTLC2 0.062 5.4E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.048 5.9E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0480184 5.9E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg23187727 chr14:78029584 SPTLC2 -0.00092 6.1E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg16464494 chr14:78032088 SPTLC2 -0.100066 6.2E-09
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg07590649 chr14:78031892 SPTLC2 -0.225381 6.6E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg18569885 chr14:78083170 SPTLC2 0.0022 6.6E-09
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg05211862 chr14:78008930 SPTLC2 1.2 6.7E-09
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.0477231 7.3E-09
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.048 8.3E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.047 8.7E-09
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.047 9E-09
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.047 9E-09
Kyung WK 32795589 DNA methylation atopy nasal polyp discovery 108 cg25532340 chr14:78047326 SPTLC2 0.052 1.2E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 -0.0543522 1.3E-08
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0469337 1.3E-08
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.047 1.3E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg08230472 chr14:78083416 SPTLC2 -8.6e-05 1.5E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg25532340 chr14:78047326 SPTLC2 0.052 1.6E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.047 1.7E-08
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.046 1.9E-08
Gadd DA 35945220 GSTZ1 protein levels (SeqId = 16872-248) DNA methylation Whole blood SomaScan protein measurement 774 cg04690379 chr14:78021619 SPTLC2 0.87 1.9E-08
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg05211862 chr14:78008930 SPTLC2 -0.0544849 2E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg26685761 chr14:78074371 SPTLC2 0.06 2.1E-08
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 -0.0461862 2.2E-08
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0461478 2.2E-08
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.046 2.5E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.045853 2.8E-08
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0458306 2.8E-08
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg14544289 chr14:78051204 SPTLC2 -0.0103 3.1E-08
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.046 3.1E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 -0.0456439 3.2E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.046 3.2E-08
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg20016490 chr14:78061135 SPTLC2 -0.02829 3.3E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.046 3.4E-08
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.046 3.4E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 -0.0517226 3.4E-08
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg05211862 chr14:78008930 SPTLC2 0.055 4.1E-08
Qi, Y 34539625 DNA methylation Chronic Spontaneous Urticaria whole blood None 190 cg06411521 chr14:77974807 SPTLC2 -0.068 4.3E-08
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 0.045 4.3E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Lung Cancer Whole blood Basic model 18364 cg25532340 chr14:78047326 SPTLC2 -0.015 4.4E-08
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0450872 4.7E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg20016490 chr14:78061135 SPTLC2 -0.0449075 5.3E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg16464494 chr14:78032088 SPTLC2 -0.0951884 5.3E-08
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0446654 6.2E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 -0.0444369 7.3E-08
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19787508 chr14:78065859 SPTLC2 0.016 7.8E-08
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg26362766 chr14:78083524 SPTLC2 0.014 8.3E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg08230472 chr14:78083416 SPTLC2 0.00044 8.5E-08
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0441882 8.6E-08
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0441754 8.7E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0440975 9.1E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg25532340 chr14:78047326 SPTLC2 -0.0500963 1E-07
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.044 1.2E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0436323 1.2E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 -0.0435779 1.3E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg25532340 chr14:78047326 SPTLC2 -0.031 1.3E-07
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.044 1.4E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg07590649 chr14:78031892 SPTLC2 0.2 1.5E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.043 1.6E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg26685761 chr14:78074371 SPTLC2 -0.055875 1.7E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg18994022 chr14:78071948 SPTLC2 -0.0539201 1.7E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg11591809 chr14:78059873 SPTLC2 -0.0430918 1.8E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0430153 1.9E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 0.043 1.9E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0429348 2E-07
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg06175025 chr14:78082992 SPTLC2 0.0097 2E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg07590649 chr14:78031892 SPTLC2 0.071 2E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 -0.0427751 2.2E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.043 2.2E-07
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0424504 2.7E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg07590649 chr14:78031892 SPTLC2 -0.0695247 2.7E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0424351 2.7E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 0.042 3.3E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg18994022 chr14:78071948 SPTLC2 -0.0526394 3.4E-07
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.042 3.6E-07
Qi, Y 34539625 DNA methylation Chronic Spontaneous Urticaria whole blood None 190 cg13713667 chr14:78057532 SPTLC2 -0.063 3.6E-07
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0419648 3.7E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg25532340 chr14:78047326 SPTLC2 -0.146487 3.8E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg16464494 chr14:78032088 SPTLC2 -0.0875125 3.9E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.042 4.1E-07
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0417706 4.2E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg14544289 chr14:78051204 SPTLC2 -0.0433228 4.4E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 0.048 4.9E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg18569885 chr14:78083170 SPTLC2 0.15 5.2E-07
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 0.041 5.3E-07
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.041 5.5E-07
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0413237 5.5E-07
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 0.041 5.6E-07
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.041 5.7E-07
Joehanes R 27651444 DNA methylation Former versus never smoking Whole blood, CD4+ T cells or monocytes Former vs never smoking 13474 cg14544289 chr14:78051204 SPTLC2 -0.0035 5.8E-07
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0412264 5.9E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 0.041 6.2E-07
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.041 6.2E-07
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0411077 6.3E-07
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.041098 6.4E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16568136 chr14:78018515 SPTLC2 -0.0410861 6.4E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.041 6.5E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0410507 6.6E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.041 8.1E-07
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0406689 8.3E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg26685761 chr14:78074371 SPTLC2 -0.0527093 8.5E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg16464494 chr14:78032088 SPTLC2 -0.064 8.7E-07
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 -0.0405748 8.8E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg27553433 chr14:78083305 SPTLC2 0.00019 9.3E-07
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0404687 9.4E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.04 9.5E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg16464494 chr14:78032088 SPTLC2 -0.0845925 9.7E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 0.04 9.8E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0404026 9.8E-07
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 0.04 1E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.04 1E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg18994022 chr14:78071948 SPTLC2 -0.0501209 1.2E-06
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.04 1.3E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg05211862 chr14:78008930 SPTLC2 -0.0482345 1.4E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0397965 1.4E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0397912 1.4E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.04 1.5E-06
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg26685761 chr14:78074371 SPTLC2 0.14 1.6E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 -0.0394257 1.8E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.039 1.8E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0393649 1.8E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0393151 1.9E-06
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg26685761 chr14:78074371 SPTLC2 0.051 2E-06
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 4 14671 cg25532340 chr14:78047326 SPTLC2 0.056 2E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.039 2.1E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.039 2.2E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg16464494 chr14:78032088 SPTLC2 -0.0817722 2.2E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg04690379 chr14:78021619 SPTLC2 0.039 2.3E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.0389583 2.4E-06
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.039 2.4E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 0.039 2.4E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 0.039 2.4E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg14544289 chr14:78051204 SPTLC2 0.0056 2.5E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg07590649 chr14:78031892 SPTLC2 -0.032 2.5E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 0.045 2.6E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0387119 2.7E-06
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0387062 2.7E-06
Sharp GC 25855720 DNA methylation Maternal underweight Cord blood Birth 601 cg08230472 chr14:78083416 SPTLC2 0.021 2.8E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.039 2.8E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0385937 2.9E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 -0.0385698 3E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.039 3E-06
Zhu X 26756918 DNA methylation Smoking Whole blood - 596 cg14544289 chr14:78051204 SPTLC2 -0.199 3.1E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg07590649 chr14:78031892 SPTLC2 -0.180905 3.3E-06
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.0383476 3.4E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg25532340 chr14:78047326 SPTLC2 -0.0521548 3.4E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.038 3.4E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg25532340 chr14:78047326 SPTLC2 -0.0436416 3.7E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg20016490 chr14:78061135 SPTLC2 -0.0381217 3.9E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg07590649 chr14:78031892 SPTLC2 -1.5 3.9E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg26685761 chr14:78074371 SPTLC2 -0.0494086 4E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg25532340 chr14:78047326 SPTLC2 -0.133219 4E-06
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg19007537 chr14:78082808 SPTLC2 1.1 4.2E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 2 14671 cg16464494 chr14:78032088 SPTLC2 0.081 4.3E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 2 14671 cg26685761 chr14:78074371 SPTLC2 -0.0492068 4.4E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg07590649 chr14:78031892 SPTLC2 0.062 4.4E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 0.038 4.5E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0378252 4.6E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg07590649 chr14:78031892 SPTLC2 -0.054 4.7E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 3 14671 cg16464494 chr14:78032088 SPTLC2 0.08 4.8E-06
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 0.044 4.9E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg07590649 chr14:78031892 SPTLC2 0.061 5E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg16464494 chr14:78032088 SPTLC2 -0.0779897 5E-06
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 -0.037655 5.1E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 3 14671 cg26685761 chr14:78074371 SPTLC2 0.049 5.1E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg16464494 chr14:78032088 SPTLC2 -0.0789915 5.4E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Pain (Self-report) Whole blood Basic model 18413 cg26685761 chr14:78074371 SPTLC2 0.14 5.4E-06
Josephine Robertson 41361833 DNA methylation P19827 whole blood OSCA model 4 14671 cg16464494 chr14:78032088 SPTLC2 -0.117249 5.6E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.037 5.7E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 0.037 5.9E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg20016490 chr14:78061135 SPTLC2 0.037 6E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0372977 6.2E-06
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.037 6.5E-06
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.037134 6.8E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg05211862 chr14:78008930 SPTLC2 0.045 7.2E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.037 7.4E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 0.043 7.6E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.037 7.7E-06
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0368875 7.9E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 0.037 7.9E-06
Gadd DA 35945220 AKR7A3 protein levels (SeqId = 18173-11) DNA methylation Whole blood SomaScan protein measurement 774 cg18569885 chr14:78083170 SPTLC2 -0.87 8.1E-06
Gadd DA 35945220 GZMA protein levels (SeqId = 3440-7) DNA methylation Whole blood SomaScan protein measurement 774 cg05211862 chr14:78008930 SPTLC2 0.71 8.1E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0368118 8.2E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg05211862 chr14:78008930 SPTLC2 0.044 8.4E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 -0.0367706 8.4E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0367071 8.7E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg26685761 chr14:78074371 SPTLC2 0.048 8.7E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.0366534 9E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 0.037 9.2E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg07590649 chr14:78031892 SPTLC2 -0.0592492 9.3E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16568136 chr14:78018515 SPTLC2 -0.0365891 9.3E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 0.037 9.5E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg18994022 chr14:78071948 SPTLC2 -0.0451862 1.1E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg25532340 chr14:78047326 SPTLC2 0.041 1.1E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg16464494 chr14:78032088 SPTLC2 -0.0765104 1.1E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg04690379 chr14:78021619 SPTLC2 0.14 1.1E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg26685761 chr14:78074371 SPTLC2 0.047 1.2E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg26685761 chr14:78074371 SPTLC2 0.046 1.2E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg25532340 chr14:78047326 SPTLC2 0.051 1.2E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 2 14671 cg14544289 chr14:78051204 SPTLC2 -0.0376882 1.2E-05
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg24171453 chr14:78079686 SPTLC2 -0.0037 1.2E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 0.036 1.2E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0360463 1.3E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0360161 1.3E-05
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg26362766 chr14:78083524 SPTLC2 -0.0016 1.3E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0359575 1.3E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg04690379 chr14:78021619 SPTLC2 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0358132 1.4E-05
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 3 14671 cg26685761 chr14:78074371 SPTLC2 0.047 1.4E-05
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 -0.0357473 1.5E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0357322 1.5E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg07590649 chr14:78031892 SPTLC2 -0.0574683 1.6E-05
Gadd DA 35945220 HLA-DQA2 protein levels (SeqId = 7757-5) DNA methylation Whole blood SomaScan protein measurement 774 cg20016490 chr14:78061135 SPTLC2 0.57 1.6E-05
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 -0.0355346 1.7E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.035356 1.8E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0352698 1.9E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.035 1.9E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 -0.0405144 2.1E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.035 2.2E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg07590649 chr14:78031892 SPTLC2 -0.0569401 2.2E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg25532340 chr14:78047326 SPTLC2 -0.048552 2.2E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg25532340 chr14:78047326 SPTLC2 -0.04064 2.2E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg16464494 chr14:78032088 SPTLC2 0.074 2.2E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 0.035 2.2E-05
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.035 2.3E-05
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg05211862 chr14:78008930 SPTLC2 0.035 2.3E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg12471732 chr14:78071150 SPTLC2 -0.0348711 2.4E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.035 2.4E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg16464494 chr14:78032088 SPTLC2 0.035 2.4E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg16464494 chr14:78032088 SPTLC2 0.072 2.5E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg26685761 chr14:78074371 SPTLC2 -0.0450244 2.5E-05
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.035 2.6E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0347226 2.6E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg25532340 chr14:78047326 SPTLC2 0.04 2.9E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg04690379 chr14:78021619 SPTLC2 -0.0345144 2.9E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg20016490 chr14:78061135 SPTLC2 0.0027 2.9E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg14544289 chr14:78051204 SPTLC2 -0.0354308 2.9E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg07590649 chr14:78031892 SPTLC2 -0.0566692 3E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.034 3E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg14544289 chr14:78051204 SPTLC2 -0.0366196 3E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0344293 3E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg25532340 chr14:78047326 SPTLC2 -0.120117 3.1E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.034 3.1E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg07590649 chr14:78031892 SPTLC2 -0.162179 3.2E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 0.034 3.2E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg25532340 chr14:78047326 SPTLC2 0.04 3.2E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 0.034 3.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg23187727 chr14:78029584 SPTLC2 0.0032 3.3E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg05211862 chr14:78008930 SPTLC2 0.041 3.3E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg07590649 chr14:78031892 SPTLC2 0.056 3.3E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.034 3.4E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg07590649 chr14:78031892 SPTLC2 -0.0552974 3.4E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 0.034 3.4E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 3 14671 cg26685761 chr14:78074371 SPTLC2 -0.0436488 3.5E-05
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 3 14671 cg26685761 chr14:78074371 SPTLC2 0.045 3.6E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg14544289 chr14:78051204 SPTLC2 0.034 3.7E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Lung Cancer Whole blood Basic model 18364 cg14544289 chr14:78051204 SPTLC2 -0.01 3.8E-05
Gadd DA 35945220 KIT protein levels (SeqId = 2475-1) DNA methylation Whole blood SomaScan protein measurement 774 cg04690379 chr14:78021619 SPTLC2 -0.64 3.8E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg26685761 chr14:78074371 SPTLC2 -0.0441701 3.8E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg13713667 chr14:78057532 SPTLC2 -0.0654668 3.8E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg07590649 chr14:78031892 SPTLC2 0.056 3.9E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg04947514 chr14:78082976 SPTLC2 0.0018 4E-05
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 -0.0338672 4.1E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 0.034 4.1E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg07590649 chr14:78031892 SPTLC2 -0.0550623 4.3E-05
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 -0.0337667 4.3E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.033692 4.5E-05
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg26685761 chr14:78074371 SPTLC2 -0.0336836 4.5E-05
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg05690233 chr14:78055578 SPTLC2 0.034 4.6E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 -0.0336378 4.6E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg05211862 chr14:78008930 SPTLC2 0.048 4.7E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.034 4.8E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg05211862 chr14:78008930 SPTLC2 -0.0454401 5E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg25532340 chr14:78047326 SPTLC2 0.033 5E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.033 5E-05
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg20434272 chr14:78070455 SPTLC2 -0.0334735 5E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.0333627 5.3E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.033 5.4E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.033 5.4E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg19007537 chr14:78082808 SPTLC2 5.9e-05 5.5E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 2 14671 cg26685761 chr14:78074371 SPTLC2 -0.0432913 5.5E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg23187727 chr14:78029584 SPTLC2 0.033 5.6E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg04690379 chr14:78021619 SPTLC2 -0.0334887 5.7E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Colorectal Cancer (Self-report) Whole blood Fully-adjusted model 14391 cg25532340 chr14:78047326 SPTLC2 -0.029 5.7E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg20016490 chr14:78061135 SPTLC2 0.033 6E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg14544289 chr14:78051204 SPTLC2 -0.0346786 6E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg06411521 chr14:77974807 SPTLC2 0.033 6.1E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg04690379 chr14:78021619 SPTLC2 0.033 6.3E-05
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg05211862 chr14:78008930 SPTLC2 0.04 7E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg07590649 chr14:78031892 SPTLC2 0.033 7.1E-05
Gadd DA 35945220 TCL1A protein levels (SeqId = 17210-2) DNA methylation Whole blood SomaScan protein measurement 774 cg16464494 chr14:78032088 SPTLC2 0.95 7.2E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg18994022 chr14:78071948 SPTLC2 -0.032742 7.3E-05
Anna Ulrich 38184627 DNA methylation Idiopathic/heritable pulmonary arterial hypertension whole blood Discovery 1655 cg16213072 chr14:78082735 SPTLC2 -66.0 7.3E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg23187727 chr14:78029584 SPTLC2 0.0088 7.4E-05
Neumann A 33184255 ADHD DNA methylation Cord Blood At birth 2477 cg19787508 chr14:78065859 SPTLC2 -1.896 7.6E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg06175025 chr14:78082992 SPTLC2 0.0013 7.8E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0326042 7.8E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg27553433 chr14:78083305 SPTLC2 0.00068 8E-05
Gadd DA 35945220 PCDHGA10 protein levels (SeqId = 6321-65) DNA methylation Whole blood SomaScan protein measurement 774 cg05690233 chr14:78055578 SPTLC2 -0.49 8.3E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg06411521 chr14:77974807 SPTLC2 -0.0504007 8.5E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 4 14671 cg02449575 chr14:78084086 SPTLC2 0.037 8.5E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg25532340 chr14:78047326 SPTLC2 0.038 8.6E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg08230472 chr14:78083416 SPTLC2 0.0038 8.9E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg06411521 chr14:77974807 SPTLC2 -0.0501357 9E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.032 9.1E-05
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 3 14671 cg08310748 chr14:77974814 SPTLC2 0.05 9.3E-05
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.032 9.4E-05
Josephine Robertson 41361833 DNA methylation P19652 whole blood OSCA model 1 14671 cg13713667 chr14:78057532 SPTLC2 -0.0322138 9.5E-05
Josephine Robertson 41361833 DNA methylation P02765 whole blood OSCA model 1 14671 cg08310748 chr14:77974814 SPTLC2 0.032 9.7E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg07590649 chr14:78031892 SPTLC2 -0.0529061 9.7E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg04690379 chr14:78021619 SPTLC2 0.12 9.9E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 4 14671 cg04947514 chr14:78082976 SPTLC2 -0.0372168 9.9E-05
Josephine Robertson 41361833 DNA methylation Q14520 whole blood OSCA model 4 14671 cg08310748 chr14:77974814 SPTLC2 0.056 1E-04

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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