EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for SREBF2

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg05509697 chr22:42229062 SREBF2 -9.4e-05 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg25932461 chr22:42229068 SREBF2 -5.6e-05 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg27479400 chr22:42228998 SREBF2 0.00053 0E+00
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg21282452 chr22:42232160 SREBF2 0.57 6.9E-126
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg15128785 chr22:42230879 SREBF2 0.75 4.5E-124
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg16000331 chr22:42230138 SREBF2 0.16 1.8E-120
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg09978077 chr22:42229983 SREBF2 0.11 3.6E-108
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg15128785 chr22:42230879 SREBF2 0.69 5.5E-106
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg12403973 chr22:42230899 SREBF2 0.59 2.2E-88
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg15128785 chr22:42230879 SREBF2 0.54 3.6E-88
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg15128785 chr22:42230879 SREBF2 0.52 5E-83
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg12403973 chr22:42230899 SREBF2 0.42 2.3E-64
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.138319 1.4E-63
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg16000331 chr22:42230138 SREBF2 0.59 7.2E-59
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.13 3.2E-58
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.16 2.1E-54
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.125754 8.7E-53
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.13 2E-52
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg09978077 chr22:42229983 SREBF2 0.62 4.3E-48
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.14 5.5E-47
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 0.15 1.6E-45
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.114021 1.2E-43
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.113856 1.6E-43
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.11 2.3E-42
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.111332 1.1E-41
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.11 3.2E-41
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.107687 4.3E-39
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.11 1.6E-38
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 0.11 1.2E-37
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.11 1.2E-37
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.11 2.1E-37
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.1 3.4E-37
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.1 9.8E-36
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg16000331 chr22:42230138 SREBF2 0.37 1.2E-35
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg12403973 chr22:42230899 SREBF2 0.37 1.3E-35
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.12 3.2E-34
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.1 9.4E-34
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 0.1 3.7E-33
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 0.1 4.1E-33
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 0.097 5.2E-32
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg02320600 chr22:42243577 SREBF2 0.47 1.9E-30
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg15128785 chr22:42230879 SREBF2 -0.15 2.4E-30
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.0942309 2.7E-30
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 0.09 1.2E-29
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0930715 1.4E-29
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg16000331 chr22:42230138 SREBF2 0.13 1.7E-28
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg02320600 chr22:42243577 SREBF2 0.42 1.8E-28
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.09 5.5E-28
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 0.089 6.7E-28
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg12403973 chr22:42230899 SREBF2 0.27 7.3E-28
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 0.11 1.2E-27
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0893857 2E-27
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0882137 9.7E-27
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.088 1.9E-26
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg09978077 chr22:42229983 SREBF2 0.3 2.7E-26
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg16000331 chr22:42230138 SREBF2 0.12 1.6E-25
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 0.089 1.8E-25
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.086 3.2E-25
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0854821 3.3E-25
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.104381 4.7E-25
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 -0.0848102 7.8E-25
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0843112 1.5E-24
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 0.084 2.9E-24
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg02320600 chr22:42243577 SREBF2 0.42 5.3E-24
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0830819 6.8E-24
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 0.083 1.3E-23
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0823245 1.7E-23
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0819567 2.7E-23
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.081 6E-23
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 0.084 8.1E-23
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.081 9.6E-23
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.08 1.4E-22
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 0.08 2.6E-22
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg16000331 chr22:42230138 SREBF2 0.28 1.1E-21
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg09978077 chr22:42229983 SREBF2 0.13 2.3E-21
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.078 5.3E-21
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0767029 5.9E-21
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg16000331 chr22:42230138 SREBF2 0.34 9.5E-21
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0769365 1E-20
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.095 1.5E-20
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 0.076 3.2E-20
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 0.079 3.8E-20
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0749858 4.1E-20
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg09978077 chr22:42229983 SREBF2 0.39 5.5E-20
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg12403973 chr22:42230899 SREBF2 -0.11 5.5E-20
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg16170490 chr22:42302146 SREBF2 0.022 5.6E-20
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0749275 1E-19
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0742233 2.2E-19
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.074 2.6E-19
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.074 3E-19
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0738018 3.2E-19
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg04682183 chr22:42292183 SREBF2 -0.567345 4.9E-19
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 0.09 5.3E-19
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 0.079 5.5E-19
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 0.079 6.5E-19
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg02320600 chr22:42243577 SREBF2 0.34 8.1E-19
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 0.072 1.8E-18
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 0.072 2.2E-18
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0719168 2.7E-18
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 0.076 2.9E-18
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0717281 3.4E-18
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.071 4.5E-18
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg09347991 chr22:42294630 SREBF2 -0.0711045 6.5E-18
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg19027130 chr22:42242382 SREBF2 0.39 6.7E-18
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg15128785 chr22:42230879 SREBF2 -0.12 6.9E-18
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.071 9.5E-18
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg09978077 chr22:42229983 SREBF2 0.24 1.1E-17
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0701477 1.8E-17
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg09978077 chr22:42229983 SREBF2 0.12 3.5E-17
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.069 4.3E-17
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0690598 5.6E-17
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0689072 6.5E-17
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg10826400 chr22:42258288 SREBF2 0.31 9.3E-17
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 0.068 1.5E-16
Kyung WK 32795589 DNA methylation eosinophilia nasal polyp discovery 129 cg15128785 chr22:42230879 SREBF2 -0.056 2E-16
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0676756 2.3E-16
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg04682183 chr22:42292183 SREBF2 -0.521394 4E-16
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0661801 1E-15
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg19027130 chr22:42242382 SREBF2 0.087 1.1E-15
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0810284 1.6E-15
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0653573 2.3E-15
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 0.065 2.4E-15
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0646568 2.9E-15
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg15128785 chr22:42230879 SREBF2 -0.11 3.5E-15
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.064885 3.6E-15
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0788539 4E-15
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0779922 4.1E-15
Kyung WK 32795589 DNA methylation atopy nasal polyp discovery 108 cg15128785 chr22:42230879 SREBF2 -0.046 4.4E-15
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 0.066 4.4E-15
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0628783 7.9E-15
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.064 9.6E-15
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 -0.0637829 1.1E-14
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 -0.0643548 1.1E-14
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0636482 1.2E-14
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg11012487 chr22:42240675 SREBF2 0.22 1.8E-14
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 0.063 2.7E-14
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0626086 3.2E-14
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.062807 3.8E-14
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.0621967 4.7E-14
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg19027130 chr22:42242382 SREBF2 0.29 5.6E-14
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 -0.0618956 6.2E-14
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg27535047 chr22:42228699 SREBF2 0.013 7.5E-14
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 0.064 1.2E-13
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg05608063 chr22:42269725 SREBF2 0.35 1.2E-13
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 0.061 1.3E-13
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0604587 1.8E-13
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg01162866 chr22:42241482 SREBF2 -0.0606061 2E-13
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg19027130 chr22:42242382 SREBF2 0.33 2.7E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg16000331 chr22:42230138 SREBF2 0.0014 3.1E-13
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 -0.0600621 3.3E-13
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0600096 3.5E-13
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 0.06 3.5E-13
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 -0.0599517 3.7E-13
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0746845 4.3E-13
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 0.06 4.6E-13
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.06 4.8E-13
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 0.06 5.2E-13
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg21282452 chr22:42232160 SREBF2 0.19 5.2E-13
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 0.06 5.3E-13
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 0.059 5.8E-13
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.075871 6.9E-13
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg11012487 chr22:42240675 SREBF2 0.19 8.9E-13
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0587687 1.3E-12
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.073 1.3E-12
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0710819 1.9E-12
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0581016 1.9E-12
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 0.058 2.1E-12
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0727012 2.3E-12
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0578691 2.3E-12
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 0.074 2.5E-12
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 0.058 2.7E-12
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 0.061 3.1E-12
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg13637042 chr22:42228724 SREBF2 -0.00019 3.2E-12
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 0.06 3.4E-12
Hedman AK 28213390 DNA methylation Serum total cholesterol Whole blood Discovery and replication 4331 cg09978077 chr22:42229983 SREBF2 5.4e-05 3.7E-12
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.057 4E-12
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg12403973 chr22:42230899 SREBF2 -0.086 4.2E-12
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 0.057 4.9E-12
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0647573 5.6E-12
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg25937494 chr22:42228971 SREBF2 0.0061 6.6E-12
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 0.062 7.2E-12
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg09978077 chr22:42229983 SREBF2 0.059 7.4E-12
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg09978077 chr22:42229983 SREBF2 0.058 7.8E-12
Hedman AK 28213390 DNA methylation Serum total cholesterol Whole blood Discovery and replication adjusted for BMI 4331 cg09978077 chr22:42229983 SREBF2 5.3e-05 8.3E-12
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 0.061 8.5E-12
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg15128785 chr22:42230879 SREBF2 -1.2 9.5E-12
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 0.056 1E-11
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg09978077 chr22:42229983 SREBF2 -0.200521 1.1E-11
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.056 1.2E-11
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.056 1.4E-11
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg23067438 chr22:42228994 SREBF2 0.00042 1.5E-11
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 0.056 1.6E-11
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.055 2.2E-11
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.0551611 2.3E-11
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 -0.0550993 2.4E-11
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0550448 2.5E-11
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 0.058 2.7E-11
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 0.061 2.7E-11
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.055 2.8E-11
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 -0.0567159 3E-11
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg10826400 chr22:42258288 SREBF2 0.26 3.1E-11
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.055 3.4E-11
Petersen A-K 24014485 M32492_caprylate_8:0 DNA methylation Whole blood snps as covariates model 1760 cg16000331 chr22:42230138 SREBF2 15.0 3.7E-11
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg09347991 chr22:42294630 SREBF2 -0.0545466 3.8E-11
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0541993 5.1E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 -0.0539342 6.3E-11
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0538984 6.5E-11
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 -0.0555635 6.9E-11
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 0.054 7.6E-11
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0535609 8.5E-11
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.054 8.6E-11
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 -0.0558191 8.7E-11
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg11012487 chr22:42240675 SREBF2 0.058 9.3E-11
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg02320600 chr22:42243577 SREBF2 0.052 9.6E-11
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0533689 9.9E-11
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 -0.0552149 1E-10
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 0.053 1.1E-10
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0662248 1.1E-10
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.053 1.2E-10
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg16351433 chr22:42258538 SREBF2 -0.047 1.3E-10
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0529759 1.4E-10
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg19027130 chr22:42242382 SREBF2 -0.0631034 1.4E-10
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg10826400 chr22:42258288 SREBF2 0.25 1.7E-10
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg19027130 chr22:42242382 SREBF2 -0.0663542 1.8E-10
Petersen A-K 24014485 M32492_caprylate_8:0 DNA methylation Whole blood no snps model 1760 cg16000331 chr22:42230138 SREBF2 13.0 1.9E-10
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.053 1.9E-10
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0524761 2E-10
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.052 2.1E-10
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.052362 2.2E-10
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg11012487 chr22:42240675 SREBF2 0.18 2.3E-10
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0522342 2.4E-10
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0521957 2.5E-10
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0518908 3.2E-10
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 -0.0518328 3.3E-10
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg21282452 chr22:42232160 SREBF2 -0.0517816 3.5E-10
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0652806 3.5E-10
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg01162866 chr22:42241482 SREBF2 -0.0515771 4.1E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg07746918 chr22:42229324 SREBF2 0.00021 4.3E-10
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg15128785 chr22:42230879 SREBF2 -0.204622 4.3E-10
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 -0.0535266 4.4E-10
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg15128785 chr22:42230879 SREBF2 -0.03 5.3E-10
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0646284 5.7E-10
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg05608063 chr22:42269725 SREBF2 0.3 5.7E-10
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 0.051 5.8E-10
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0515258 6E-10
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 -0.0544929 6E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 0.051 6E-10
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0513016 6.7E-10
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 -0.0508294 7.3E-10
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 -0.0508177 7.3E-10
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg04682183 chr22:42292183 SREBF2 0.38 7.5E-10
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0626569 7.7E-10
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0507213 7.9E-10
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 0.052 8E-10
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 0.054 8.1E-10
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 -0.0514883 8.7E-10
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0489919 8.7E-10
Imgenberg-Kreuz J 26857698 DNA methylation Primary Sjogrens syndrome Whole blood Whole blood 500 cg09978077 chr22:42229983 SREBF2 NA 9.2E-10
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 -0.0529297 9.3E-10
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 -0.0504791 9.5E-10
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 0.05 1E-09
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 0.05 1E-09
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg16000331 chr22:42230138 SREBF2 0.068 1E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 0.05 1.1E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0502853 1.1E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 -0.0529042 1.1E-09
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg23227119 chr22:42290034 SREBF2 0.39 1.2E-09
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.05 1.3E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0495548 1.3E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.05 1.4E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg02320600 chr22:42243577 SREBF2 0.051 1.4E-09
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 -0.0524714 1.4E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg09978077 chr22:42229983 SREBF2 0.052 1.7E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 0.051 1.7E-09
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0496412 1.8E-09
Hedman AK 28213390 DNA methylation Serum total cholesterol Whole blood Discovery 2306 cg09978077 chr22:42229983 SREBF2 5.7e-05 1.8E-09
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 0.05 1.8E-09
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg01162866 chr22:42241482 SREBF2 0.05 1.9E-09
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg09978077 chr22:42229983 SREBF2 0.052 1.9E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 -0.0494693 2E-09
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0622421 2.3E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 -0.0504342 2.3E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 -0.0492912 2.3E-09
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0496794 2.4E-09
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 0.049 2.4E-09
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg09978077 chr22:42229983 SREBF2 0.052 2.5E-09
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0491966 2.5E-09
Hedman AK 28213390 DNA methylation Serum total cholesterol Whole blood Discovery adjusted for BMI 2306 cg09978077 chr22:42229983 SREBF2 5.7e-05 3E-09
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 0.052 3.1E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 0.049 3.1E-09
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.0488791 3.2E-09
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0488479 3.2E-09
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0472633 3.5E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 0.049 3.5E-09
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0599102 3.5E-09
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg09978077 chr22:42229983 SREBF2 0.08 3.8E-09
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg10826400 chr22:42258288 SREBF2 0.051 4E-09
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.049 4E-09
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 -0.0494533 4.5E-09
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 -0.050681 5E-09
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg04477345 chr22:42292872 SREBF2 -0.290961 5E-09
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0482219 5.1E-09
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 0.048 5.6E-09
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg04682183 chr22:42292183 SREBF2 -0.37156 5.9E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0479964 6E-09
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Fully-adjusted model 14391 cg15128785 chr22:42230879 SREBF2 -0.085 6.1E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 0.048 6.2E-09
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.048 6.4E-09
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0483246 6.7E-09
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg01162866 chr22:42241482 SREBF2 0.21 7.1E-09
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0477443 7.2E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg01162866 chr22:42241482 SREBF2 -0.0477333 7.3E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.06 7.6E-09
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 0.048 7.6E-09
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg11012487 chr22:42240675 SREBF2 0.05 7.8E-09
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.048 7.8E-09
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 0.048 8.2E-09
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0475017 8.6E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.047 8.9E-09
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 -0.0474305 9E-09
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 -0.0478536 9.3E-09
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 -0.0498577 9.9E-09
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 -0.0472884 1E-08
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0472463 1E-08
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg09978077 chr22:42229983 SREBF2 -0.169475 1E-08
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.047138 1.1E-08
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0470862 1.2E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 0.05 1.2E-08
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 0.05 1.2E-08
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.047 1.2E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg02320600 chr22:42243577 SREBF2 -0.242341 1.2E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0470137 1.2E-08
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0468765 1.3E-08
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.047 1.4E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.046919 1.5E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0467314 1.5E-08
Sayols-Baixeras S 28173150 Serum total cholesterol DNA methylation Whole blood Discovery and replication adjusted for surrogate variables 3187 cg16000331 chr22:42230138 SREBF2 4.9 1.5E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 0.047 1.5E-08
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 0.047 1.6E-08
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg09347991 chr22:42294630 SREBF2 0.047 1.7E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 0.047 1.7E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 -0.0500974 1.8E-08
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg09978077 chr22:42229983 SREBF2 -0.0486709 2E-08
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0462983 2E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0462585 2.1E-08
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg02320600 chr22:42243577 SREBF2 0.047 2.1E-08
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.046 2.2E-08
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 0.046 2.3E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 -0.0464552 2.3E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 -0.0459796 2.5E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg15128785 chr22:42230879 SREBF2 -0.156194 2.5E-08
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg15128785 chr22:42230879 SREBF2 -0.183674 2.6E-08
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0552388 2.6E-08
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0458155 2.8E-08
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.057 3E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 0.049 3.1E-08
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 0.046 3.2E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 -0.0455999 3.3E-08
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.046 3.4E-08
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg10826400 chr22:42258288 SREBF2 0.21 3.4E-08
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.045936 3.5E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg09978077 chr22:42229983 SREBF2 0.045 3.7E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 -0.0453686 3.9E-08
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0453574 3.9E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg02320600 chr22:42243577 SREBF2 -0.215939 4.1E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.045 4.3E-08
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.045 4.5E-08
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.056 4.6E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg16000331 chr22:42230138 SREBF2 -0.062508 4.8E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 -0.0450192 4.9E-08
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg11012487 chr22:42240675 SREBF2 0.15 5.1E-08
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.044905 5.3E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 -0.0448817 5.4E-08
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg16351433 chr22:42258538 SREBF2 -0.073716 5.4E-08
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 -0.0448454 5.5E-08
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0447338 5.9E-08
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 -0.0446861 6.1E-08
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0450441 6.3E-08
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg02458785 chr22:42293245 SREBF2 0.046 6.3E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 -0.0446278 6.4E-08
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg16351433 chr22:42258538 SREBF2 -0.0710517 6.8E-08
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.044533 6.8E-08
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 -0.0444797 7.1E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.045 7.2E-08
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0448713 7.5E-08
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg01162866 chr22:42241482 SREBF2 0.21 7.5E-08
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0445956 7.6E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg16170490 chr22:42302146 SREBF2 -0.00048 7.7E-08
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg02458785 chr22:42293245 SREBF2 0.048 8E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.044 8.1E-08
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.043233 8.3E-08
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg11012487 chr22:42240675 SREBF2 0.044 8.3E-08
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0441037 9.1E-08
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 -0.0440809 9.2E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg19027130 chr22:42242382 SREBF2 0.21 9.3E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg12767332 chr22:42271413 SREBF2 -0.227967 9.7E-08
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.044 9.8E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 -0.0439078 1E-07
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 0.044 1E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg02458785 chr22:42293245 SREBF2 0.047 1.1E-07
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 0.044 1.2E-07
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg16000331 chr22:42230138 SREBF2 NA 1.2E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0436966 1.3E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0543276 1.3E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg23227119 chr22:42290034 SREBF2 -0.0435402 1.3E-07
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.044 1.3E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg16351433 chr22:42258538 SREBF2 -0.0794439 1.5E-07
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0527184 1.5E-07
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg13637042 chr22:42228724 SREBF2 0.0076 1.5E-07
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.054 1.5E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg09978077 chr22:42229983 SREBF2 0.0034 1.6E-07
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.043 1.6E-07
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.050444 1.7E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg09978077 chr22:42229983 SREBF2 0.045 1.8E-07
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 -0.0436851 1.9E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 -0.044929 1.9E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 0.043 2.1E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg02458785 chr22:42293245 SREBF2 0.046 2.2E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg01162866 chr22:42241482 SREBF2 0.2 2.2E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg19027130 chr22:42242382 SREBF2 -0.094 2.3E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0426703 2.3E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0425165 2.4E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg19027130 chr22:42242382 SREBF2 -0.0555773 2.4E-07
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.053227 2.4E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.0425599 2.5E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg21282452 chr22:42232160 SREBF2 -0.043814 2.5E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 -0.0429869 2.6E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg09978077 chr22:42229983 SREBF2 -0.0442313 2.6E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg21282452 chr22:42232160 SREBF2 0.042 2.9E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0423902 2.9E-07
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg23227119 chr22:42290034 SREBF2 -0.0422994 3E-07
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 -0.0427938 3.4E-07
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.0420852 3.4E-07
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg05608063 chr22:42269725 SREBF2 0.062 3.7E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.042 3.7E-07
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.042 3.8E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.042 3.9E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg21282452 chr22:42232160 SREBF2 0.042 3.9E-07
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg21282452 chr22:42232160 SREBF2 0.13 4.3E-07
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.042 4.3E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg04682183 chr22:42292183 SREBF2 0.059 4.4E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg12403973 chr22:42230899 SREBF2 -0.023 4.7E-07
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg15128785 chr22:42230879 SREBF2 -0.141529 4.8E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 -0.0421157 5E-07
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 0.041 5.2E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg16000331 chr22:42230138 SREBF2 0.058 5.4E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0416382 5.6E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0416553 5.8E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 0.045 5.8E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg09978077 chr22:42229983 SREBF2 -0.0430492 5.9E-07
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 0.041 6.1E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.042 6.1E-07
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.041 6.1E-07
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0410592 6.5E-07
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0410583 6.5E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 3 14671 cg16351433 chr22:42258538 SREBF2 -0.0649136 6.5E-07
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg15128785 chr22:42230879 SREBF2 -0.163275 6.8E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg21282452 chr22:42232160 SREBF2 0.041 6.9E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg23227119 chr22:42290034 SREBF2 -0.0409701 6.9E-07
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 0.041 7E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 0.044 7E-07
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 -0.0430548 7.4E-07
Darina Czamara 38600394 DNA methylation sex placenta meta-analysis of robust linear regression results per cohort 746 cg16000331 chr22:42230138 SREBF2 -0.1472972 7.4E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg16351433 chr22:42258538 SREBF2 -0.0670164 7.4E-07
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0408276 7.5E-07
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 0.041 7.9E-07
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.041 8E-07
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0406905 8.2E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg01162866 chr22:42241482 SREBF2 -0.0406748 8.3E-07
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.041 8.3E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 0.041 8.7E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0405641 8.9E-07
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 4 14671 cg16351433 chr22:42258538 SREBF2 -0.077054 9E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg02320600 chr22:42243577 SREBF2 -0.089 9E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg19027130 chr22:42242382 SREBF2 -0.092 9.1E-07
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg27535047 chr22:42228699 SREBF2 0.0075 9.2E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg19027130 chr22:42242382 SREBF2 0.052 9.6E-07
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.04 9.7E-07
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 0.04 1E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 -0.0403765 1E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0401685 1.1E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg11012487 chr22:42240675 SREBF2 -0.0440165 1.2E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg16000331 chr22:42230138 SREBF2 -0.068 1.2E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0400025 1.3E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 -0.0425354 1.3E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 -0.0399661 1.3E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 4 14671 cg19027130 chr22:42242382 SREBF2 0.05 1.3E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0398421 1.4E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 0.04 1.4E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0397797 1.4E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0397739 1.4E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 0.042 1.5E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 0.04 1.5E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0396943 1.5E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg27479400 chr22:42228998 SREBF2 0.0019 1.6E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg04682183 chr22:42292183 SREBF2 -1.8 1.6E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg04682183 chr22:42292183 SREBF2 -0.0574203 1.6E-06
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.04 1.7E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0395495 1.7E-06
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.04 1.7E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 -0.0415761 1.7E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg02458785 chr22:42293245 SREBF2 0.042 1.7E-06
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 0.042 1.7E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg04682183 chr22:42292183 SREBF2 -0.0571491 1.8E-06
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 3 14671 cg09978077 chr22:42229983 SREBF2 -0.0413513 1.9E-06
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg15128785 chr22:42230879 SREBF2 -0.133494 1.9E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 -0.0393097 1.9E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 -0.0391773 2.1E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg16000331 chr22:42230138 SREBF2 -0.0547072 2.1E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Basic model 18059 cg12403973 chr22:42230899 SREBF2 -0.06 2.1E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 -0.0424303 2.1E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 3 14671 cg09978077 chr22:42229983 SREBF2 0.041 2.1E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.039 2.2E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg02458785 chr22:42293245 SREBF2 0.042 2.2E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0492523 2.2E-06
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0390044 2.3E-06
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0490757 2.4E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 -0.0411381 2.5E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 -0.0407015 2.6E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg05608063 chr22:42269725 SREBF2 0.058 2.7E-06
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 0.039 2.7E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg23067438 chr22:42228994 SREBF2 0.14 2.8E-06
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg10826400 chr22:42258288 SREBF2 -4.7 2.9E-06
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg16351433 chr22:42258538 SREBF2 -0.0634493 2.9E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg05360632 chr22:42280865 SREBF2 0.17 2.9E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 0.039 2.9E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg09347991 chr22:42294630 SREBF2 -0.0385874 2.9E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.039 3E-06
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.0385551 3E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 0.042 3E-06
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg05509697 chr22:42229062 SREBF2 1.0 3.1E-06
Cardenas A 31300640 DNA methylation fractional exhaled nitric oxide (FeNO) nasal epithelium None 517 cg15128785 chr22:42230879 SREBF2 -4.74 3.1E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 -0.0384546 3.2E-06
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 2 14671 cg09978077 chr22:42229983 SREBF2 -0.0403553 3.3E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg09978077 chr22:42229983 SREBF2 -0.059895 3.4E-06
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0383287 3.4E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 4 14671 cg04682183 chr22:42292183 SREBF2 0.057 3.5E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Stroke (Self-report) Whole blood Basic model 18056 cg15128785 chr22:42230879 SREBF2 -0.044 3.6E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.038237 3.6E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 0.038 3.6E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 -0.0381959 3.7E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 -0.0389072 3.7E-06
Josephine Robertson 41361833 DNA methylation A0A0C4DH29 whole blood OSCA model 1 14671 cg23227119 chr22:42290034 SREBF2 -0.0381633 3.8E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 -0.0386362 3.8E-06
Inkster A 34044884 DNA methylation Sex Placenta Discovery 585 cg16000331 chr22:42230138 SREBF2 4.0 3.8E-06
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.038035 4.1E-06
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0468381 4.1E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg09347991 chr22:42294630 SREBF2 -0.0379644 4.2E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0379603 4.2E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.0378866 4.4E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg02320600 chr22:42243577 SREBF2 -0.0374513 4.5E-06
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0381279 4.7E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0371918 4.9E-06
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 0.042 5E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg02114066 chr22:42244821 SREBF2 0.19 5.1E-06
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 -0.0376125 5.2E-06
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 0.038 5.2E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 -0.0402657 5.3E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0479224 5.4E-06
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 3 14671 cg15128785 chr22:42230879 SREBF2 -0.0375472 5.4E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0375292 5.4E-06
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0375058 5.5E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 3 14671 cg02458785 chr22:42293245 SREBF2 0.039 5.7E-06
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 0.037 5.8E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg16351433 chr22:42258538 SREBF2 -0.0677919 5.8E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg02458785 chr22:42293245 SREBF2 0.04 5.9E-06
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 -0.039607 6.2E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 0.038 6.3E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 0.04 6.4E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg09978077 chr22:42229983 SREBF2 -0.0390934 6.5E-06
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg02458785 chr22:42293245 SREBF2 0.043 6.6E-06
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 0.037 6.6E-06
Bohlin J 27717397 DNA methylation Gestational age Cord blood Last menstrual period-estimated gestational age 1068 cg16000331 chr22:42230138 SREBF2 -0.00027552 6.8E-06
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 -0.0403952 6.9E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.037 7.2E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 4 14671 cg16351433 chr22:42258538 SREBF2 -0.069824 7.3E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg02039517 chr22:42280570 SREBF2 0.15 7.4E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.036976 7.5E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.045943 7.6E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 4 14671 cg04682183 chr22:42292183 SREBF2 0.053 7.7E-06
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0369196 7.7E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 0.037 7.8E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0368832 7.9E-06
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg01162866 chr22:42241482 SREBF2 -0.036806 8.2E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0371075 8.2E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 -0.0367943 8.3E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg12767332 chr22:42271413 SREBF2 0.2 8.3E-06
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 0.037 8.4E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg26613723 chr22:42228508 SREBF2 0.15 8.4E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg04682183 chr22:42292183 SREBF2 -0.0523778 8.7E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg16000331 chr22:42230138 SREBF2 -0.024 8.7E-06
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg23227119 chr22:42290034 SREBF2 0.26 8.7E-06
Josephine Robertson 41361833 DNA methylation P04275 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.037 8.8E-06
Sayols-Baixeras S 28173150 Serum total cholesterol DNA methylation Whole blood Discovery adjusted for surrogate variables 645 cg16000331 chr22:42230138 SREBF2 9.0 9E-06
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg21282452 chr22:42232160 SREBF2 -0.0362365 9.1E-06
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 4 14671 cg19027130 chr22:42242382 SREBF2 -0.0477539 9.6E-06
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 -0.0392953 9.7E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0365018 9.8E-06
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 -0.0390394 1E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.036 1.1E-05
Gross AM 27105112 DNA methylation HIV infection Whole blood Discovery 181 cg13637042 chr22:42228724 SREBF2 -0.959439 1.1E-05
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 -0.0389728 1.1E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.036 1.1E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg02320600 chr22:42243577 SREBF2 -0.188192 1.1E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg11012487 chr22:42240675 SREBF2 -0.0376547 1.1E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 -0.0362695 1.1E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg21282452 chr22:42232160 SREBF2 -0.0362139 1.1E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg21282452 chr22:42232160 SREBF2 -0.0357078 1.2E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 3 14671 cg21282452 chr22:42232160 SREBF2 0.035 1.2E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg02458785 chr22:42293245 SREBF2 0.038 1.2E-05
Gadd DA 35945220 EPHB6 protein levels (SeqId = 5078-82) DNA methylation Whole blood SomaScan protein measurement 774 cg00830626 chr22:42229212 SREBF2 -0.68 1.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Stroke (Self-report) Whole blood Basic model 18056 cg12403973 chr22:42230899 SREBF2 -0.039 1.2E-05
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0467083 1.2E-05
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 4 14671 cg02458785 chr22:42293245 SREBF2 0.042 1.2E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 0.039 1.2E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0361022 1.2E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg09347991 chr22:42294630 SREBF2 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0360213 1.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg21282452 chr22:42232160 SREBF2 -0.01 1.3E-05
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 0.04 1.3E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg01162866 chr22:42241482 SREBF2 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 0.036 1.3E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg21282452 chr22:42232160 SREBF2 -0.0359109 1.4E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg09978077 chr22:42229983 SREBF2 -0.188023 1.4E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 0.039 1.4E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 -0.0368803 1.4E-05
Gadd DA 35945220 HMGCS1 protein levels (SeqId = 13496-19) DNA methylation Whole blood SomaScan protein measurement 774 cg15128785 chr22:42230879 SREBF2 -0.64 1.4E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 0.036 1.4E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 -0.039481 1.4E-05
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 2 14671 cg16351433 chr22:42258538 SREBF2 -0.0589578 1.4E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.036 1.4E-05
Sayols-Baixeras S 28173150 Serum total cholesterol DNA methylation Whole blood Discovery and replication 3187 cg16000331 chr22:42230138 SREBF2 3.2 1.5E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 -0.0357061 1.5E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 0.036 1.5E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg21282452 chr22:42232160 SREBF2 -0.0356894 1.5E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 -0.0375624 1.6E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 -0.0374989 1.6E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 0.036 1.7E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 -0.0355499 1.7E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 0.035 1.7E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg02320600 chr22:42243577 SREBF2 -0.0356371 1.7E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 4 14671 cg02320600 chr22:42243577 SREBF2 -0.0392342 1.7E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg27535047 chr22:42228699 SREBF2 0.035 1.8E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg23227119 chr22:42290034 SREBF2 -0.0353749 1.8E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 -0.0353516 1.8E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.043 1.9E-05
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 0.035 1.9E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 -0.0353045 1.9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Fully-adjusted model 14391 cg02320600 chr22:42243577 SREBF2 -0.087 1.9E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 0.038 1.9E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg09347991 chr22:42294630 SREBF2 -0.0352773 1.9E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0352598 1.9E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 -0.0352497 1.9E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.0352217 2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg09978077 chr22:42229983 SREBF2 -0.058 2E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg21282452 chr22:42232160 SREBF2 0.11 2E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg02458785 chr22:42293245 SREBF2 0.037 2.1E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg09978077 chr22:42229983 SREBF2 -0.0359059 2.1E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0351217 2.1E-05
Gadd DA 35945220 NEGR1 protein levels (SeqId = 7050-5) DNA methylation Whole blood SomaScan protein measurement 774 cg00830626 chr22:42229212 SREBF2 -0.657 2.1E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg01162866 chr22:42241482 SREBF2 -0.0385716 2.1E-05
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 3 14671 cg16351433 chr22:42258538 SREBF2 -0.0578448 2.2E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 0.037 2.2E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.035 2.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Ischemic Heart Disease (Self-report) Whole blood Fully-adjusted model 14391 cg23227119 chr22:42290034 SREBF2 -0.13 2.2E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 0.037 2.2E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.035009 2.2E-05
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg21282452 chr22:42232160 SREBF2 -0.0349837 2.3E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg17157956 chr22:42273901 SREBF2 0.11 2.3E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 0.035 2.3E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg09978077 chr22:42229983 SREBF2 -1.9 2.3E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 0.038 2.3E-05
Josephine Robertson 41361833 DNA methylation P01344 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0348751 2.4E-05
Gadd DA 35945220 PRG3 protein levels (SeqId = 9015-1) DNA methylation Whole blood SomaScan protein measurement 774 cg01162866 chr22:42241482 SREBF2 -0.69 2.4E-05
Gadd DA 35945220 UNC5B protein levels (SeqId = 7776-20) DNA methylation Whole blood SomaScan protein measurement 774 cg06382651 chr22:42235793 SREBF2 -0.37 2.4E-05
Josephine Robertson 41361833 DNA methylation P02787 whole blood OSCA model 4 14671 cg16000331 chr22:42230138 SREBF2 -0.0493433 2.4E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg21282452 chr22:42232160 SREBF2 -0.0350496 2.4E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg02320600 chr22:42243577 SREBF2 0.035 2.4E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg04682183 chr22:42292183 SREBF2 -0.037987 2.5E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg27535047 chr22:42228699 SREBF2 -0.027 2.5E-05
Gadd DA 35945220 HMOX1 protein levels (SeqId = 17398-55) DNA methylation Whole blood SomaScan protein measurement 774 cg26613723 chr22:42228508 SREBF2 -0.77 2.5E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0347748 2.5E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg23227119 chr22:42290034 SREBF2 -0.0358602 2.5E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg16351433 chr22:42258538 SREBF2 -0.0571471 2.5E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg05608063 chr22:42269725 SREBF2 0.051 2.5E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg02320600 chr22:42243577 SREBF2 -0.0321165 2.6E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0347381 2.6E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0428117 2.6E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 0.038 2.6E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 0.038 2.6E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg04682183 chr22:42292183 SREBF2 -0.051142 2.7E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 0.038 2.7E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0346135 2.7E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.0346131 2.7E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.035 2.8E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 -0.0372398 2.8E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg19027130 chr22:42242382 SREBF2 -0.0417751 2.8E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0440335 2.9E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0345406 2.9E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg19027130 chr22:42242382 SREBF2 -0.034505 2.9E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 -0.0344645 3E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0442285 3E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.035 3E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg02320600 chr22:42243577 SREBF2 -0.164647 3E-05
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg09347991 chr22:42294630 SREBF2 0.034 3E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.0344197 3E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 0.037 3E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg01162866 chr22:42241482 SREBF2 0.035 3.1E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 0.036 3.1E-05
Sayols-Baixeras S 28173150 Serum total cholesterol DNA methylation Whole blood Replication adjusted for surrogate variables 2542 cg16000331 chr22:42230138 SREBF2 4.0 3.1E-05
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 4 14671 cg16000331 chr22:42230138 SREBF2 -0.0491468 3.1E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0343742 3.1E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 -0.034331 3.2E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg19027130 chr22:42242382 SREBF2 -1.1 3.2E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 4 14671 cg02458785 chr22:42293245 SREBF2 0.04 3.3E-05
Josephine Robertson 41361833 DNA methylation O95445 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 0.035 3.3E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0342254 3.4E-05
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg09347991 chr22:42294630 SREBF2 -0.0342058 3.4E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 -0.0360977 3.5E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg05608063 chr22:42269725 SREBF2 -0.192095 3.5E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg27479400 chr22:42228998 SREBF2 0.13 3.5E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 0.037 3.6E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg12403973 chr22:42230899 SREBF2 -0.0341052 3.6E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 2 14671 cg05360632 chr22:42280865 SREBF2 -0.0342294 3.6E-05
Josephine Robertson 41361833 DNA methylation P05543 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0340731 3.7E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1V2 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0429599 3.7E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0340545 3.7E-05
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg23227119 chr22:42290034 SREBF2 0.034 3.8E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 3 14671 cg05836598 chr22:42294680 SREBF2 -0.0341087 3.8E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg02320600 chr22:42243577 SREBF2 -0.0345005 3.9E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.034 3.9E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg16000331 chr22:42230138 SREBF2 -0.0353536 3.9E-05
Josephine Robertson 41361833 DNA methylation P06727 whole blood OSCA model 4 14671 cg16000331 chr22:42230138 SREBF2 -0.0478215 3.9E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg05360632 chr22:42280865 SREBF2 -0.146922 4E-05
Gadd DA 35945220 ST6GALNAC5 protein levels (SeqId = 7927-16) DNA methylation Whole blood SomaScan protein measurement 774 cg16351433 chr22:42258538 SREBF2 -0.98 4E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.0338858 4E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 4 14671 cg04682183 chr22:42292183 SREBF2 -0.0504758 4.1E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg04682183 chr22:42292183 SREBF2 -0.0368212 4.1E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 1 14671 cg05836598 chr22:42294680 SREBF2 -0.0338195 4.2E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg21282452 chr22:42232160 SREBF2 0.11 4.2E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 0.037 4.3E-05
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg15128785 chr22:42230879 SREBF2 -0.133992 4.3E-05
Gadd DA 35945220 TAPBPL protein levels (SeqId = 6364-7) DNA methylation Whole blood SomaScan protein measurement 774 cg00830626 chr22:42229212 SREBF2 -0.63 4.3E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0340144 4.3E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 0.034 4.3E-05
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 1 14671 cg09978077 chr22:42229983 SREBF2 -0.0337491 4.3E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 2 14671 cg05836598 chr22:42294680 SREBF2 -0.0338488 4.5E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Inflammatory Bowel Disease Whole blood Basic model 17959 cg02320600 chr22:42243577 SREBF2 -0.022 4.5E-05
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0424705 4.5E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg11012487 chr22:42240675 SREBF2 0.034 4.5E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg02320600 chr22:42243577 SREBF2 -0.160312 4.6E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg19027130 chr22:42242382 SREBF2 0.044 4.6E-05
Gadd DA 35945220 KLK11 protein levels (SeqId = 2831-29) DNA methylation Whole blood SomaScan protein measurement 774 cg00830626 chr22:42229212 SREBF2 -0.628 4.7E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg02320600 chr22:42243577 SREBF2 -1.4 4.7E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg09978077 chr22:42229983 SREBF2 -0.0352447 4.7E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg02114066 chr22:42244821 SREBF2 -0.0518964 4.8E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg21282452 chr22:42232160 SREBF2 -0.0337644 4.9E-05
Darina Czamara 38600394 DNA methylation sex placenta meta-analysis of robust linear regression results per cohort 746 cg09978077 chr22:42229983 SREBF2 -0.1020159 4.9E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg10826400 chr22:42258288 SREBF2 -0.0349152 5E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 0.033 5E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 0.041 5E-05
Gadd DA 35945220 TREML2 protein levels (SeqId = 5736-1) DNA methylation Whole blood SomaScan protein measurement 774 cg00830626 chr22:42229212 SREBF2 -0.63 5.1E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 -0.0336023 5.1E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 -0.0348598 5.2E-05
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg19027130 chr22:42242382 SREBF2 -0.0362434 5.2E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 1 14671 cg02320600 chr22:42243577 SREBF2 0.033 5.2E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 0.033 5.3E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 4 14671 cg04682183 chr22:42292183 SREBF2 -0.0480786 5.4E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg04682183 chr22:42292183 SREBF2 -0.0455796 5.4E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg10826400 chr22:42258288 SREBF2 -0.0333397 5.4E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 2 14671 cg12403973 chr22:42230899 SREBF2 -0.0348537 5.6E-05
Gadd DA 35945220 PAPPA protein levels (SeqId = 4148-49) DNA methylation Whole blood SomaScan protein measurement 774 cg01162866 chr22:42241482 SREBF2 -0.65 5.6E-05
Gross AM 27105112 DNA methylation HIV infection Neutrophils Neutrophils 60 cg20107653 chr22:42228989 SREBF2 -0.170949 5.7E-05
Gadd DA 35945220 GRN protein levels (SeqId = 4992-49) DNA methylation Whole blood SomaScan protein measurement 774 cg06382651 chr22:42235793 SREBF2 -0.36 5.7E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg23227119 chr22:42290034 SREBF2 0.26 5.7E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg02458785 chr22:42293245 SREBF2 0.038 5.8E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg01162866 chr22:42241482 SREBF2 0.033 5.8E-05
Gadd DA 35945220 RPN1 protein levels (SeqId = 6458-6) DNA methylation Whole blood SomaScan protein measurement 774 cg00830626 chr22:42229212 SREBF2 -0.62 5.8E-05
Gadd DA 35945220 GZMA protein levels (SeqId = 3440-7) DNA methylation Whole blood SomaScan protein measurement 774 cg09978077 chr22:42229983 SREBF2 -0.6 5.8E-05
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 0.033 5.9E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 3 14671 cg23227119 chr22:42290034 SREBF2 -0.0341122 5.9E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 2 14671 cg06382651 chr22:42235793 SREBF2 0.033 6E-05
Soerensen M 32327964 DNA methylation Cognitive function Whole blood None 452 cg16170490 chr22:42302146 SREBF2 0.013 6E-05
Josephine Robertson 41361833 DNA methylation P13671 whole blood OSCA model 4 14671 cg16351433 chr22:42258538 SREBF2 -0.0629562 6E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg02114066 chr22:42244821 SREBF2 -0.0520658 6.2E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 4 14671 cg19027130 chr22:42242382 SREBF2 0.043 6.4E-05
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 -0.0329581 6.5E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg01162866 chr22:42241482 SREBF2 0.14 6.5E-05
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 1 14671 cg16351433 chr22:42258538 SREBF2 -0.0329417 6.6E-05
Cardenas A 31300640 DNA methylation fractional exhaled nitric oxide (FeNO) nasal epithelium None 517 cg01162866 chr22:42241482 SREBF2 -1.87 6.6E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 4 14671 cg09978077 chr22:42229983 SREBF2 -0.0555954 6.6E-05
Gadd DA 35945220 DPEP1 protein levels (SeqId = 8794-13) DNA methylation Whole blood SomaScan protein measurement 774 cg27535047 chr22:42228699 SREBF2 -0.82 6.7E-05
Gadd DA 35945220 KRT20 protein levels (SeqId = 12975-11) DNA methylation Whole blood SomaScan protein measurement 774 cg15128785 chr22:42230879 SREBF2 -0.58 6.7E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg15128785 chr22:42230879 SREBF2 -0.0379596 6.7E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg02458785 chr22:42293245 SREBF2 0.033 6.8E-05
Battram T None DNA methylation Ribs bone mineral density Whole blood None 702 cg07746918 chr22:42229324 SREBF2 1.4 6.8E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 0.034 6.9E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH29 whole blood OSCA model 3 14671 cg23227119 chr22:42290034 SREBF2 -0.0340568 6.9E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg27535047 chr22:42228699 SREBF2 -0.0328439 6.9E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg06382651 chr22:42235793 SREBF2 0.033 7E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg11012487 chr22:42240675 SREBF2 -0.0345039 7E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.0419524 7.1E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg09978077 chr22:42229983 SREBF2 -0.021 7.2E-05
Gadd DA 35945220 TFF3 protein levels (SeqId = 4721-54) DNA methylation Whole blood SomaScan protein measurement 774 cg06382651 chr22:42235793 SREBF2 -0.35 7.3E-05
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg26613723 chr22:42228508 SREBF2 -0.0326857 7.5E-05
Gadd DA 35945220 GNS protein levels (SeqId = 3616-3) DNA methylation Whole blood SomaScan protein measurement 774 cg00830626 chr22:42229212 SREBF2 -0.61 7.8E-05
Gross AM 27105112 DNA methylation HIV infection Neutrophils Neutrophils 60 cg12856612 chr22:42228819 SREBF2 -0.235101 7.8E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 2 14671 cg09978077 chr22:42229983 SREBF2 0.034 7.8E-05
Gadd DA 35945220 CXCL12 protein levels (SeqId = 3516-60) DNA methylation Whole blood SomaScan protein measurement 774 cg02320600 chr22:42243577 SREBF2 0.76 8E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg09978077 chr22:42229983 SREBF2 -0.116433 8E-05
Josephine Robertson 41361833 DNA methylation Q96PD5 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0325157 8.2E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1V2 whole blood OSCA model 1 14671 cg15128785 chr22:42230879 SREBF2 -0.0325094 8.2E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg16000331 chr22:42230138 SREBF2 -0.0346701 8.2E-05
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg16351433 chr22:42258538 SREBF2 0.19 8.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg27535047 chr22:42228699 SREBF2 0.00088 8.4E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg10826400 chr22:42258288 SREBF2 -0.0335717 8.5E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 3 14671 cg09978077 chr22:42229983 SREBF2 0.034 8.5E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 -0.032369 8.8E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 4 14671 cg06382651 chr22:42235793 SREBF2 0.033 8.9E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.032 8.9E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 4 14671 cg05836598 chr22:42294680 SREBF2 -0.0337193 9.1E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 4 14671 cg12403973 chr22:42230899 SREBF2 -0.040771 9.2E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg15128785 chr22:42230879 SREBF2 0.033 9.3E-05
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg11012487 chr22:42240675 SREBF2 0.037 9.3E-05
Gadd DA 35945220 WISP1 protein levels (SeqId = 13692-154) DNA methylation Whole blood SomaScan protein measurement 774 cg00830626 chr22:42229212 SREBF2 -0.602 9.3E-05
Sharp G 33517419 DNA methylation Maternal body mass index Cord blood Adjusted for paternal BMI using cord blood in males only 2530 cg16000331 chr22:42230138 SREBF2 -0.00221 9.4E-05
Gadd DA 35945220 LARGE protein levels (SeqId = 7935-26) DNA methylation Whole blood SomaScan protein measurement 774 cg16351433 chr22:42258538 SREBF2 -0.935 9.4E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg09347991 chr22:42294630 SREBF2 -0.0322328 9.4E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 0.032 9.4E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg10826400 chr22:42258288 SREBF2 0.034 9.5E-05
Gadd DA 35945220 TAGLN protein levels (SeqId = 15640-54) DNA methylation Whole blood SomaScan protein measurement 774 cg06382651 chr22:42235793 SREBF2 -0.34 9.7E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I1 whole blood OSCA model 1 14671 cg02114066 chr22:42244821 SREBF2 -0.032176 9.7E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg04682183 chr22:42292183 SREBF2 -0.0321683 9.7E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg01162866 chr22:42241482 SREBF2 0.032 9.8E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg05608063 chr22:42269725 SREBF2 -0.0321614 9.8E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg19027130 chr22:42242382 SREBF2 -0.0342809 9.8E-05
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 3 14671 cg12403973 chr22:42230899 SREBF2 -0.033517 9.8E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 1 14671 cg16000331 chr22:42230138 SREBF2 -0.032137 9.9E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg16000331 chr22:42230138 SREBF2 -0.057 9.9E-05
Gadd DA 35945220 PAF protein levels (SeqId = 19158-1) DNA methylation Whole blood SomaScan protein measurement 774 cg15128785 chr22:42230879 SREBF2 0.57 9.9E-05

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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