EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for TIGIT

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg09246203 chr3:114018592 TIGIT -0.002 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg13669740 chr3:114012833 TIGIT -0.0021 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg19421218 chr3:114012659 TIGIT -0.0042 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg19456938 chr3:114012806 TIGIT -0.0029 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg20832020 chr3:114012912 TIGIT -0.0031 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg22577252 chr3:114012316 TIGIT -0.0033 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg22870429 chr3:114027859 TIGIT -0.0052 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg22870429 chr3:114027859 TIGIT 0.016 0E+00
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg13669740 chr3:114012833 TIGIT -0.16424 1.1E-94
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg22577252 chr3:114012316 TIGIT 0.18 4.3E-91
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19456938 chr3:114012806 TIGIT -0.16709 3.9E-89
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg20832020 chr3:114012912 TIGIT -0.13785 4.1E-75
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.14 8.6E-68
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.14 1.2E-63
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.13 1.8E-60
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.13 1.2E-52
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.12 7.3E-48
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg22870429 chr3:114027859 TIGIT NA 5.5E-45
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.11 1.2E-42
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.11 6.3E-42
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 2636786 (gene symbol: TIGIT) Whole blood Meta-analysis 4170 cg09246203 chr3:114018592 TIGIT NA 1.4E-39
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.11 1.8E-39
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg09246203 chr3:114018592 TIGIT -0.05755 6.1E-39
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.11 1E-38
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg22577252 chr3:114012316 TIGIT NA 7.8E-38
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg20832020 chr3:114012912 TIGIT NA 5.2E-37
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19421218 chr3:114012659 TIGIT -0.08981 3.7E-36
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.1 5.9E-35
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.097 4E-32
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.094 3.6E-30
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.093 1.1E-29
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.093 1.4E-29
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg22870429 chr3:114027859 TIGIT -0.438401 1.1E-28
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg12767903 chr3:114027886 TIGIT -0.370259 2.4E-28
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.091 3.2E-28
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.09 5.2E-28
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg22870429 chr3:114027859 TIGIT -2.6 1.7E-27
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg19456938 chr3:114012806 TIGIT 0.0015 2.2E-27
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0883222 8.4E-27
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.088 8.5E-27
Wozniak MB 23526956 DNA methylation Clear cell renal carcinoma Clear cell renal carcinoma tumour cells and adjacent healthy cells - 129 cg09246203 chr3:114018592 TIGIT NA 1.1E-26
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg12767903 chr3:114027886 TIGIT -0.061 1.1E-26
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.085 4.8E-25
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0843908 1.3E-24
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg22870429 chr3:114027859 TIGIT -0.39853 7E-24
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.081 9E-23
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.081 1E-22
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT -0.0808464 1E-22
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg22870429 chr3:114027859 TIGIT -0.064 3.1E-22
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 2636786 (gene symbol: TIGIT) Whole blood Meta-analysis 4170 cg20832020 chr3:114012912 TIGIT NA 7.4E-22
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg12767903 chr3:114027886 TIGIT -0.317589 3.6E-21
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 2636786 (gene symbol: TIGIT) Whole blood Meta-analysis 4170 cg19456938 chr3:114012806 TIGIT NA 5.4E-21
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.077 6E-21
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT 0.076 4.6E-20
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.074 1.9E-19
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg19456938 chr3:114012806 TIGIT -0.104303 2.8E-19
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT 0.073 7.5E-19
Sikdar S 31536415 DNA methylation Smoking Whole blood, CD4+ T cells, CD14+ monocytes random effects meta-analysis 15907 cg22870429 chr3:114027859 TIGIT -0.00682 1.7E-18
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg12767903 chr3:114027886 TIGIT -1.9 2.6E-18
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0718966 2.8E-18
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg09246203 chr3:114018592 TIGIT 0.0012 2.9E-18
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT -0.0833638 5E-18
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg12767903 chr3:114027886 TIGIT -0.288837 7.1E-18
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg12767903 chr3:114027886 TIGIT 0.28 7.3E-18
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg22870429 chr3:114027859 TIGIT -0.338737 8.9E-18
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.07 1.8E-17
Dugue PA 31552803 DNA methylation Smoking Whole blood Current vs never smoking 1851 cg22870429 chr3:114027859 TIGIT -0.13 2.2E-17
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT -0.0954973 2.4E-17
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.069 3.9E-17
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.069 6.5E-17
Yao C 33752734 DNA methylation Gene expression of Affymetrix ID: 2636786 (gene symbol: TIGIT) Whole blood Meta-analysis 4170 cg13669740 chr3:114012833 TIGIT NA 1.4E-16
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0681149 1.5E-16
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.068 1.5E-16
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg22577252 chr3:114012316 TIGIT 0.0021 2.5E-16
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg13669740 chr3:114012833 TIGIT 0.0011 3.9E-16
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.067 5.8E-16
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg13669740 chr3:114012833 TIGIT -0.0909708 7.1E-16
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.066 1.2E-15
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.066 1.3E-15
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.066 1.8E-15
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT 0.077 2.2E-15
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.065 2.2E-15
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg11306217 chr3:114026249 TIGIT -0.334829 2.3E-15
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT 0.089 2.4E-15
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.065 2.7E-15
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT -0.065099 3E-15
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg19456938 chr3:114012806 TIGIT -0.0906648 6.4E-15
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.064 1.3E-14
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT -0.0632064 1.8E-14
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT -0.0629811 2.3E-14
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg12767903 chr3:114027886 TIGIT -0.11 2.3E-14
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.063 3E-14
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT 0.073 3.5E-14
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.062 4.1E-14
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0622503 4.5E-14
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT -0.0729133 4.5E-14
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0620884 5.2E-14
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.062 7.1E-14
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0615653 8.4E-14
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.061 9.6E-14
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg09755142 chr3:114018493 TIGIT 0.061 9.9E-14
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT -0.0830091 1.5E-13
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg22870429 chr3:114027859 TIGIT -0.390504 1.7E-13
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT -0.060676 1.9E-13
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT -0.060403 2.4E-13
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT 0.06 2.6E-13
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT 0.082 2.6E-13
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg11306217 chr3:114026249 TIGIT -0.0891213 4.9E-13
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.059 6.1E-13
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.059 7.1E-13
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT -0.0801918 8.3E-13
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0590094 8.5E-13
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT 0.059 1.1E-12
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg22870429 chr3:114027859 TIGIT -0.373955 1.2E-12
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT -0.0685885 1.5E-12
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT -0.0582732 1.6E-12
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0582423 1.7E-12
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg22870429 chr3:114027859 TIGIT -0.02923 1.8E-12
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT 0.058 1.8E-12
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg13669740 chr3:114012833 TIGIT -0.0792975 1.9E-12
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0578427 2.4E-12
Zeilinger S 23691101 DNA methylation Smoking Whole blood Current vs never smoking discovery 1011 cg22870429 chr3:114027859 TIGIT NA 2.8E-12
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT -0.0575803 3E-12
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.057 3.8E-12
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.057 5.2E-12
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT 0.057 5.9E-12
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.057 6.7E-12
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT 0.057 7.1E-12
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT 0.056 8E-12
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg22870429 chr3:114027859 TIGIT 0.26 1.1E-11
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.056 1.2E-11
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0556037 1.6E-11
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0554149 1.9E-11
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.055 2.2E-11
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg19456938 chr3:114012806 TIGIT -0.215604 3E-11
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg22577252 chr3:114012316 TIGIT -0.0545788 3.7E-11
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.054 6.4E-11
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT 0.054 7.2E-11
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg20832020 chr3:114012912 TIGIT -0.0675516 7.5E-11
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg12767903 chr3:114027886 TIGIT -0.044 7.6E-11
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg22870429 chr3:114027859 TIGIT -0.049 2.6E-10
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg22577252 chr3:114012316 TIGIT -0.0528091 2.9E-10
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT 0.061 3E-10
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg12767903 chr3:114027886 TIGIT -0.0718565 3.4E-10
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT -0.0516956 3.7E-10
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.052 3.9E-10
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg09755142 chr3:114018493 TIGIT 0.052 4E-10
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0514273 4.6E-10
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT 0.051 5.3E-10
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.051 6.2E-10
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.051 7.2E-10
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT -0.0507793 7.6E-10
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.051 7.6E-10
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT -0.0504528 9.7E-10
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg11306217 chr3:114026249 TIGIT -0.0753668 1E-09
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0501767 1.2E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT 0.05 1.6E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.05 1.6E-09
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT -0.0577003 1.8E-09
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.049488 2E-09
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0494461 2.1E-09
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT 0.067 2.3E-09
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT -0.0491729 2.5E-09
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0490917 2.7E-09
Liu C 27843151 DNA methylation Alcohol consumption per day CD14+ monocytes CD14+ monocytes 1251 cg20832020 chr3:114012912 TIGIT -0.00021 3E-09
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.049 3.5E-09
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg22870429 chr3:114027859 TIGIT -0.311696 3.6E-09
Guida F 25556184 DNA methylation Smoking Whole blood Current vs never smoking 582 cg22870429 chr3:114027859 TIGIT -0.12 4.1E-09
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.048 4.6E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg19421218 chr3:114012659 TIGIT 0.0019 5E-09
Joehanes R 27651444 DNA methylation Current versus never smoking Whole blood, CD4+ T cells or monocytes Current vs never smoking 9389 cg22870429 chr3:114027859 TIGIT -0.0149 5E-09
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT -0.0563735 5.7E-09
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0480685 5.7E-09
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.048 6.5E-09
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0478249 6.8E-09
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0476518 7.7E-09
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg11306217 chr3:114026249 TIGIT 0.071 9.4E-09
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.047341 9.6E-09
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg11306217 chr3:114026249 TIGIT -0.242102 9.9E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg20832020 chr3:114012912 TIGIT 0.0012 1E-08
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.047 1.2E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.046723 1.5E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT -0.0635492 1.6E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg22577252 chr3:114012316 TIGIT -0.245112 1.6E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg11306217 chr3:114026249 TIGIT -0.0686959 1.7E-08
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 2 14671 cg09246203 chr3:114018592 TIGIT 0.055 1.9E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg12767903 chr3:114027886 TIGIT 0.064 2E-08
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg09246203 chr3:114018592 TIGIT -0.0543996 2E-08
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0462791 2E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg15200017 chr3:114026049 TIGIT 0.051 2.1E-08
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0462071 2.2E-08
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT 0.054 2.3E-08
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg18114756 chr3:114024972 TIGIT -0.0460279 2.4E-08
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.046 2.5E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.046 2.9E-08
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.046 3E-08
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg22870429 chr3:114027859 TIGIT 0.054 3E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg22870429 chr3:114027859 TIGIT 0.054 3.2E-08
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg19456938 chr3:114012806 TIGIT -0.179698 3.3E-08
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT 0.049 3.4E-08
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.045 3.8E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg23676679 chr3:114013739 TIGIT -0.146542 3.8E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg15200017 chr3:114026049 TIGIT -0.0500599 3.8E-08
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.045 3.9E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg20832020 chr3:114012912 TIGIT -0.056951 3.9E-08
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT -0.0451837 4.4E-08
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT -0.0613486 4.9E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Ischemic Heart Disease Whole blood Basic model 17483 cg22870429 chr3:114027859 TIGIT -0.041 5.4E-08
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 3 14671 cg22870429 chr3:114027859 TIGIT -0.0523095 5.5E-08
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0447877 5.7E-08
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0447665 5.8E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.045 5.9E-08
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.045 6.1E-08
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0445838 6.6E-08
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT -0.0445398 6.8E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg11306217 chr3:114026249 TIGIT 0.22 6.9E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg19456938 chr3:114012806 TIGIT 0.005 7.7E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg13669740 chr3:114012833 TIGIT -0.194905 8.2E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Ischemic Heart Disease Whole blood Basic model 17483 cg12767903 chr3:114027886 TIGIT -0.034 8.6E-08
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg20832020 chr3:114012912 TIGIT -0.197315 9.1E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 4 14671 cg22870429 chr3:114027859 TIGIT 0.07 9.5E-08
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg22577252 chr3:114012316 TIGIT -0.04 1E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg22577252 chr3:114012316 TIGIT -0.0444522 1.1E-07
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg11306217 chr3:114026249 TIGIT -0.225085 1.1E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Lung Cancer Whole blood Basic model 18364 cg12767903 chr3:114027886 TIGIT -0.016 1.1E-07
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT 0.052 1.1E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT -0.0437647 1.1E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg19421218 chr3:114012659 TIGIT -0.0577551 1.2E-07
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT 0.044 1.2E-07
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.044 1.4E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg22870429 chr3:114027859 TIGIT -0.0514117 1.5E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT 0.043 1.6E-07
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg11306217 chr3:114026249 TIGIT 0.064 1.7E-07
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.043 1.8E-07
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT 0.043 2E-07
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.043 2.1E-07
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT -0.0428601 2.1E-07
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0428437 2.1E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT 0.05 2.2E-07
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0427063 2.3E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg19456938 chr3:114012806 TIGIT -0.0717011 2.3E-07
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.043 2.6E-07
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0424704 2.7E-07
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT 0.058 2.8E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0423916 2.8E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a fixed effect 2338 cg19421218 chr3:114012659 TIGIT -0.0091 2.9E-07
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.042 3.1E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.042 3.1E-07
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0422234 3.1E-07
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT -0.0422201 3.1E-07
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT 0.042 3.2E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0421265 3.3E-07
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0420762 3.4E-07
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.041919 3.8E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg19456938 chr3:114012806 TIGIT -0.029 3.8E-07
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT -0.0419005 3.8E-07
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg22577252 chr3:114012316 TIGIT -1.6 4E-07
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT -0.0489538 4.2E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT 0.042 4.2E-07
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT -0.0485377 4.5E-07
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0416431 4.5E-07
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT 0.042 4.7E-07
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.041502 4.9E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Pain (Self-report) Whole blood Basic model 18413 cg12767903 chr3:114027886 TIGIT -0.17 5E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT 0.041 5.2E-07
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 3 14671 cg19456938 chr3:114012806 TIGIT -0.0577604 5.2E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 4 14671 cg22870429 chr3:114027859 TIGIT -0.0644116 5.3E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg09755142 chr3:114018493 TIGIT 0.041 5.3E-07
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg19421218 chr3:114012659 TIGIT -0.152823 5.8E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT 0.056 6E-07
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0410663 6.5E-07
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 3 14671 cg19456938 chr3:114012806 TIGIT -0.057694 6.7E-07
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0409499 7E-07
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg19456938 chr3:114012806 TIGIT -0.033 7.1E-07
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg19421218 chr3:114012659 TIGIT -0.0537018 7.2E-07
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 4 14671 cg11306217 chr3:114026249 TIGIT -0.0854772 7.9E-07
Gadd DA 35945220 GZMK protein levels (SeqId = 9545-156) DNA methylation Whole blood SomaScan protein measurement 774 cg09246203 chr3:114018592 TIGIT -0.72 8.5E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT -0.0406259 8.5E-07
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 4 14671 cg19421218 chr3:114012659 TIGIT 0.062 9.1E-07
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0404963 9.3E-07
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0403772 1E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg22870429 chr3:114027859 TIGIT -0.085 1E-06
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0403384 1E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT -0.0402848 1.1E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg13669740 chr3:114012833 TIGIT -0.176601 1.2E-06
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT -0.046884 1.3E-06
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg13669740 chr3:114012833 TIGIT -0.0547301 1.3E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT -0.0399801 1.3E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT -0.0468291 1.3E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0397826 1.4E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0397401 1.5E-06
Gadd DA 35945220 IGHM protein levels (SeqId = 3069-52) DNA methylation Whole blood SomaScan protein measurement 774 cg09246203 chr3:114018592 TIGIT -0.704 1.5E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.04 1.6E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT 0.04 1.6E-06
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT -0.0395557 1.6E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0395052 1.7E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT -0.0394647 1.7E-06
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.039 1.8E-06
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg19456938 chr3:114012806 TIGIT -0.361464 1.8E-06
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg19456938 chr3:114012806 TIGIT -0.0556358 1.9E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.039 1.9E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT -0.0535233 2E-06
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.039 2.1E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0390514 2.2E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg13669740 chr3:114012833 TIGIT -0.0628099 2.3E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg09246203 chr3:114018592 TIGIT -0.0463114 2.3E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.039 2.7E-06
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT -0.0454409 2.7E-06
Gadd DA 35945220 GZMK protein levels (SeqId = 9545-156) DNA methylation Whole blood SomaScan protein measurement 774 cg11306217 chr3:114026249 TIGIT -1.05 2.8E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg13669740 chr3:114012833 TIGIT -0.035 2.9E-06
Dugue PA 31552803 DNA methylation Smoking Whole blood Former vs never smoking 156 cg22870429 chr3:114027859 TIGIT -0.05 2.9E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg12767903 chr3:114027886 TIGIT -0.203107 3.2E-06
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT 0.038 3.3E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg12767903 chr3:114027886 TIGIT -0.201435 3.4E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg11306217 chr3:114026249 TIGIT -0.0570846 3.5E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Chronic Pain (Self-report) Whole blood Basic model 18413 cg22870429 chr3:114027859 TIGIT -0.18 3.6E-06
Gadd DA 35945220 CFHR1 protein levels (SeqId = 15468-14) DNA methylation Whole blood SomaScan protein measurement 774 cg22870429 chr3:114027859 TIGIT -0.91 3.6E-06
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg20832020 chr3:114012912 TIGIT -0.171369 3.7E-06
Kashima K 33564054 DNA methylation gestational age Cord blood None 110 cg22870429 chr3:114027859 TIGIT 0.003 3.7E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT -0.0381813 3.7E-06
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg12767903 chr3:114027886 TIGIT 0.2 3.9E-06
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg18114756 chr3:114024972 TIGIT -0.0380703 4E-06
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT -0.0380441 4E-06
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0380201 4.1E-06
Bohlin J 27717397 DNA methylation Gestational age Cord blood Ultrasound-estimated gestational age 1068 cg20832020 chr3:114012912 TIGIT 0.00039 4.1E-06
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0379796 4.2E-06
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0379359 4.3E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg15200017 chr3:114026049 TIGIT 0.042 4.5E-06
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg09246203 chr3:114018592 TIGIT 0.051 4.6E-06
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.038 4.7E-06
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0377227 4.9E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg12767903 chr3:114027886 TIGIT 0.052 4.9E-06
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0376929 5E-06
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT -0.0376232 5.2E-06
Josephine Robertson 41361833 DNA methylation P04196 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT -0.0376024 5.2E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg11306217 chr3:114026249 TIGIT -0.033 5.3E-06
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg11306217 chr3:114026249 TIGIT 0.056 5.6E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg11306217 chr3:114026249 TIGIT 0.056 5.6E-06
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg19456938 chr3:114012806 TIGIT 0.053 5.8E-06
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 2 14671 cg23676679 chr3:114013739 TIGIT -0.0412111 5.8E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0374109 5.8E-06
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT 0.037 5.9E-06
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg09246203 chr3:114018592 TIGIT -0.135649 6E-06
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg22577252 chr3:114012316 TIGIT 0.038 6.5E-06
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg11306217 chr3:114026249 TIGIT 0.055 6.5E-06
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 3 14671 cg13669740 chr3:114012833 TIGIT -0.0506615 6.6E-06
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 3 14671 cg13669740 chr3:114012833 TIGIT -0.0502078 6.7E-06
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0370628 7.1E-06
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg22577252 chr3:114012316 TIGIT -0.194428 7.4E-06
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg12767903 chr3:114027886 TIGIT -0.072 7.9E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT -0.0368251 8.1E-06
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.037 8.3E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.037 8.5E-06
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg09246203 chr3:114018592 TIGIT -0.13331 8.6E-06
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.037 8.7E-06
Liu C 27843151 DNA methylation Alcohol consumption per day Whole blood African ancestry 2423 cg22870429 chr3:114027859 TIGIT -4.57e-05 8.8E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 3 14671 cg13669740 chr3:114012833 TIGIT -0.0499438 9.2E-06
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.037 9.3E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg09246203 chr3:114018592 TIGIT 0.0034 9.4E-06
Christiansen C 33593402 DNA methylation Smoking Whole blood Current vs never smoking meta-analysis in European samples 912 cg12767903 chr3:114027886 TIGIT NA 9.5E-06
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT -0.0434262 9.6E-06
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT -0.0426877 1E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0364094 1E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg11306217 chr3:114026249 TIGIT 0.054 1.1E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT -0.0430704 1.1E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0363206 1.1E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 2 14671 cg15200017 chr3:114026049 TIGIT 0.04 1.1E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.036 1.1E-05
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0361495 1.2E-05
Battram T None DNA methylation Ratio of monounsaturated fatty acids to total fatty acids Whole blood None 669 cg22870429 chr3:114027859 TIGIT -0.036 1.2E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.036 1.2E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg11306217 chr3:114026249 TIGIT -0.0537879 1.3E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg11306217 chr3:114026249 TIGIT -0.0528875 1.3E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg19456938 chr3:114012806 TIGIT 0.051 1.3E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg23676679 chr3:114013739 TIGIT -0.116477 1.3E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 2 14671 cg13669740 chr3:114012833 TIGIT -0.0491172 1.3E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT -0.0427177 1.3E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg19421218 chr3:114012659 TIGIT -0.0473273 1.4E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0358937 1.4E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0358845 1.4E-05
Gadd DA 35945220 TNFRSF17 protein levels (SeqId = 2665-26) DNA methylation Whole blood SomaScan protein measurement 774 cg13669740 chr3:114012833 TIGIT -0.84 1.4E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 2 14671 cg22577252 chr3:114012316 TIGIT -0.03616 1.4E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT 0.036 1.4E-05
Darina Czamara 38600394 DNA methylation sex placenta meta-analysis of robust linear regression results per cohort 746 cg18114756 chr3:114024972 TIGIT 0.14 1.4E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg20832020 chr3:114012912 TIGIT -0.432909 1.5E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT 0.042 1.5E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0356686 1.6E-05
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg22577252 chr3:114012316 TIGIT -0.0356536 1.6E-05
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT 0.041 1.6E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg19421218 chr3:114012659 TIGIT 0.047 1.6E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 4 14671 cg19421218 chr3:114012659 TIGIT -0.0546171 1.6E-05
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg22870429 chr3:114027859 TIGIT -0.226857 1.6E-05
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0355573 1.6E-05
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 3 14671 cg19456938 chr3:114012806 TIGIT -0.0499055 1.7E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT 0.036 1.7E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT 0.048 1.7E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0354602 1.7E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT -0.035382 1.8E-05
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0353425 1.9E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT -0.0416588 2E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg22870429 chr3:114027859 TIGIT 0.22 2E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0351415 2.1E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0351001 2.1E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT 0.035 2.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg20832020 chr3:114012912 TIGIT -0.032 2.2E-05
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT -0.0476387 2.3E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT 0.035 2.4E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg19421218 chr3:114012659 TIGIT -0.92 2.4E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT 0.048 2.4E-05
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.035 2.5E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg19456938 chr3:114012806 TIGIT -0.0489471 2.6E-05
Josephine Robertson 41361833 DNA methylation Q9BXR6 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.035 2.6E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg09246203 chr3:114018592 TIGIT 0.041 2.6E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg15200017 chr3:114026049 TIGIT -0.036 2.6E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Rheumatoid Arthritis (Self-report) Whole blood Basic model 18055 cg12767903 chr3:114027886 TIGIT -0.052 2.6E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent COPD (Self-report) Whole blood Basic model 18078 cg12767903 chr3:114027886 TIGIT -0.042 2.6E-05
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0347088 2.6E-05
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT -0.0473803 2.6E-05
Josephine Robertson 41361833 DNA methylation A0A0G2JMB2 whole blood OSCA model 3 14671 cg15200017 chr3:114026049 TIGIT -0.0382347 2.7E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1V0 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT -0.0411543 2.7E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT -0.0406012 2.8E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 2 14671 cg19456938 chr3:114012806 TIGIT -0.048463 3E-05
Battram T None DNA methylation Ribs bone mineral density Whole blood None 702 cg22870429 chr3:114027859 TIGIT -1.31 3E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0344441 3E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT -0.0344284 3E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 4 14671 cg09246203 chr3:114018592 TIGIT 0.047 3.3E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0342779 3.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg09246203 chr3:114018592 TIGIT 0.0039 3.4E-05
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0342027 3.4E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg09246203 chr3:114018592 TIGIT 0.041 3.4E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg13669740 chr3:114012833 TIGIT -0.44532 3.5E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg22577252 chr3:114012316 TIGIT -0.179607 3.7E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg23676679 chr3:114013739 TIGIT -0.0374759 3.7E-05
Battram T None DNA methylation Triglycerides in IDL Whole blood None 683 cg22870429 chr3:114027859 TIGIT -2.8 3.7E-05
Josephine Robertson 41361833 DNA methylation P02775 whole blood OSCA model 3 14671 cg15200017 chr3:114026049 TIGIT 0.038 3.7E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 3 14671 cg19456938 chr3:114012806 TIGIT -0.0479489 3.7E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0340188 3.8E-05
Josephine Robertson 41361833 DNA methylation P02760 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT 0.04 3.8E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.034 3.8E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg22577252 chr3:114012316 TIGIT 0.17 3.8E-05
Karlsson Linner R 29086770 DNA methylation Educational attainment Whole blood Basic model 10767 cg22870429 chr3:114027859 TIGIT NA 3.9E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT 0.04 4E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0339017 4E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg13669740 chr3:114012833 TIGIT 0.046 4E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 4 14671 cg09246203 chr3:114018592 TIGIT -0.0455776 4.1E-05
Gadd DA 35945220 CAST protein levels (SeqId = 3026-5) DNA methylation Whole blood SomaScan protein measurement 774 cg09246203 chr3:114018592 TIGIT -0.6 4.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg11306217 chr3:114026249 TIGIT -0.035 4.2E-05
Josephine Robertson 41361833 DNA methylation P00450 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.034 4.2E-05
Battram T None DNA methylation Monounsaturated fatty acids 16:1 18:1 Whole blood None 667 cg22870429 chr3:114027859 TIGIT -0.131 4.3E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT -0.0337457 4.3E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 3 14671 cg09246203 chr3:114018592 TIGIT -0.0399895 4.4E-05
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.0337331 4.4E-05
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg15200017 chr3:114026049 TIGIT -0.199967 4.5E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg09246203 chr3:114018592 TIGIT -0.021 4.6E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg09246203 chr3:114018592 TIGIT -0.26771 4.7E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0335968 4.7E-05
Josephine Robertson 41361833 DNA methylation P08571 whole blood OSCA model 1 14671 cg11306217 chr3:114026249 TIGIT 0.034 4.7E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0335322 4.9E-05
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT -0.0335225 4.9E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg23676679 chr3:114013739 TIGIT -0.108142 4.9E-05
Battram T None DNA methylation Triglycerides to total lipids ratio in medium HDL Whole blood None 683 cg22870429 chr3:114027859 TIGIT -0.072 4.9E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg18114756 chr3:114024972 TIGIT -0.033057 4.9E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg20832020 chr3:114012912 TIGIT 0.042 4.9E-05
Josephine Robertson 41361833 DNA methylation Q15848 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT 0.039 5E-05
Battram T None DNA methylation Phospholipids in small VLDL Whole blood None 683 cg22870429 chr3:114027859 TIGIT -2.1 5.1E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0334057 5.2E-05
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 3 14671 cg11306217 chr3:114026249 TIGIT 0.049 5.2E-05
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 3 14671 cg11306217 chr3:114026249 TIGIT -0.0501813 5.2E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg20832020 chr3:114012912 TIGIT -0.026 5.4E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg18114756 chr3:114024972 TIGIT -0.0329293 5.4E-05
Josephine Robertson 41361833 DNA methylation P10643 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT 0.033 5.6E-05
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0332072 5.7E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 4 14671 cg19456938 chr3:114012806 TIGIT 0.058 5.9E-05
Battram T None DNA methylation Free cholesterol in small VLDL Whole blood None 683 cg22870429 chr3:114027859 TIGIT -3.1 6E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 3 14671 cg13669740 chr3:114012833 TIGIT -0.0452554 6.1E-05
Gadd DA 35945220 FAIM3 protein levels (SeqId = 6574-11) DNA methylation Whole blood SomaScan protein measurement 774 cg09246203 chr3:114018592 TIGIT -0.585 6.1E-05
Josephine Robertson 41361833 DNA methylation P51884 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT -0.0330311 6.3E-05
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0330231 6.3E-05
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg22870429 chr3:114027859 TIGIT -0.0330041 6.4E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg09246203 chr3:114018592 TIGIT -0.0329864 6.4E-05
Battram T None DNA methylation Free cholesterol to total lipids ratio in large LDL Whole blood None 680 cg22870429 chr3:114027859 TIGIT 0.087 6.6E-05
Josephine Robertson 41361833 DNA methylation P27169 whole blood OSCA model 2 14671 cg22870429 chr3:114027859 TIGIT 0.039 6.7E-05
Josephine Robertson 41361833 DNA methylation C9JB55 whole blood OSCA model 2 14671 cg11306217 chr3:114026249 TIGIT -0.0491387 6.8E-05
Josephine Robertson 41361833 DNA methylation P25311 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT 0.033 6.8E-05
Josephine Robertson 41361833 DNA methylation P01742 whole blood OSCA model 1 14671 cg19421218 chr3:114012659 TIGIT 0.033 6.9E-05
Josephine Robertson 41361833 DNA methylation P02763 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT -0.0447712 6.9E-05
Josephine Robertson 41361833 DNA methylation P15169 whole blood OSCA model 3 14671 cg15200017 chr3:114026049 TIGIT 0.036 6.9E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg23676679 chr3:114013739 TIGIT -0.0359525 7.1E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 2 14671 cg13669740 chr3:114012833 TIGIT 0.045 7.3E-05
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg19456938 chr3:114012806 TIGIT -0.128443 7.5E-05
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg12767903 chr3:114027886 TIGIT -0.032691 7.5E-05
Gross AM 27105112 DNA methylation HIV infection CD4+ T-cells CD4+ T-cells 60 cg22577252 chr3:114012316 TIGIT -0.289537 7.6E-05
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg19456938 chr3:114012806 TIGIT -0.032671 7.6E-05
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident COPD Whole blood Basic model 17902 cg13669740 chr3:114012833 TIGIT -0.025 7.6E-05
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0326154 7.8E-05
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg11306217 chr3:114026249 TIGIT -0.0488979 7.8E-05
Josephine Robertson 41361833 DNA methylation P01031 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT 0.033 7.9E-05
Josephine Robertson 41361833 DNA methylation P04217 whole blood OSCA model 1 14671 cg23676679 chr3:114013739 TIGIT 0.033 8E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg15200017 chr3:114026049 TIGIT -0.0324553 8.4E-05
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg11306217 chr3:114026249 TIGIT 0.048 8.4E-05
Gadd DA 35945220 GZMK protein levels (SeqId = 9545-156) DNA methylation Whole blood SomaScan protein measurement 774 cg20832020 chr3:114012912 TIGIT -0.77 8.8E-05
Josephine Robertson 41361833 DNA methylation P01008 whole blood OSCA model 2 14671 cg12767903 chr3:114027886 TIGIT 0.044 9E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg13669740 chr3:114012833 TIGIT -0.0323109 9.1E-05
Battram T None DNA methylation Triglycerides in small HDL Whole blood None 682 cg22870429 chr3:114027859 TIGIT -6.6 9.1E-05
Josephine Robertson 41361833 DNA methylation P02647 whole blood OSCA model 1 14671 cg22577252 chr3:114012316 TIGIT 0.032 9.1E-05
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg12767903 chr3:114027886 TIGIT -0.16995 9.2E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg19421218 chr3:114012659 TIGIT 0.0058 9.5E-05
Josephine Robertson 41361833 DNA methylation P00734 whole blood OSCA model 1 14671 cg20832020 chr3:114012912 TIGIT -0.0322088 9.5E-05
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 3 14671 cg15200017 chr3:114026049 TIGIT -0.0356003 9.6E-05
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 4 14671 cg20832020 chr3:114012912 TIGIT 0.048 9.8E-05
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg11306217 chr3:114026249 TIGIT 0.048 9.9E-05

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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