Search results for TPK1
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01832012 | chr7:144437395 | TPK1 | 0.0031 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg11183253 | chr7:144347841 | TPK1 | -0.00096 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg18956562 | chr7:144149304 | TPK1 | -0.0031 | 0E+00 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg18956562 | chr7:144149304 | TPK1 | 0.011 | 0E+00 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg14468856 | chr7:144437456 | TPK1 | -0.55842 | 3.2E-158 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg01173941 | chr7:144262949 | TPK1 | 0.51 | 4.8E-134 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg18992848 | chr7:144531951 | TPK1 | -0.41228 | 7.3E-119 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg18956562 | chr7:144149304 | TPK1 | 0.32 | 1.2E-97 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg01832012 | chr7:144437395 | TPK1 | -0.19961 | 3.8E-93 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg18956562 | chr7:144149304 | TPK1 | 0.0029 | 4.1E-78 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.150379 | 6E-75 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.131799 | 7.6E-58 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg06018711 | chr7:144352927 | TPK1 | 0.089 | 2.2E-57 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg21690631 | chr7:144368888 | TPK1 | 0.065 | 4.6E-56 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg23307858 | chr7:144533454 | TPK1 | 0.073 | 7.8E-51 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.117442 | 3.2E-46 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.12 | 1.3E-44 |
| Wozniak MB | 23526956 | DNA methylation | Clear cell renal carcinoma | Clear cell renal carcinoma tumour cells and adjacent healthy cells | - | 129 | cg18992848 | chr7:144531951 | TPK1 | NA | 7E-42 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.11 | 3.4E-41 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.105503 | 1.4E-37 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg14268194 | chr7:144226107 | TPK1 | 0.085 | 1.7E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.103728 | 2.2E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.1 | 2.6E-36 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.098 | 7.4E-33 |
| Sikdar S | 31536415 | DNA methylation | Smoking | Whole blood, CD4+ T cells, CD14+ monocytes | random effects meta-analysis | 15907 | cg18956562 | chr7:144149304 | TPK1 | 0.012 | 1.5E-31 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg14468856 | chr7:144437456 | TPK1 | 0.0013 | 2.1E-31 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.091 | 1.7E-28 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg21370481 | chr7:144533376 | TPK1 | 0.062 | 3.7E-27 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0878555 | 1.5E-26 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.087 | 4E-26 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3077766 (gene symbol: TPK1) | Whole blood | Meta-analysis | 4170 | cg02641052 | chr7:144531399 | TPK1 | NA | 4E-25 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg21073826 | chr7:144273837 | TPK1 | 0.053 | 1.4E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0840412 | 2.1E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.083 | 4.6E-24 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | -0.0823158 | 1.7E-23 |
| Bonder MJ | 25282492 | DNA methylation | Fetal vs adult liver | Liver | - | 195 | cg21370481 | chr7:144533376 | TPK1 | 1.5 | 2.1E-23 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3077766 (gene symbol: TPK1) | Whole blood | Meta-analysis | 4170 | cg23307858 | chr7:144533454 | TPK1 | NA | 2.5E-23 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg06847417 | chr7:144515907 | TPK1 | -0.297503 | 1.1E-22 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0798007 | 3.7E-22 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg11183253 | chr7:144347841 | TPK1 | 0.00077 | 1.3E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0759202 | 3.3E-20 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.076 | 3.4E-20 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3077766 (gene symbol: TPK1) | Whole blood | Meta-analysis | 4170 | cg13120875 | chr7:144533471 | TPK1 | NA | 7.3E-20 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg06847417 | chr7:144515907 | TPK1 | -0.276105 | 1.7E-19 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg00201968 | chr7:144354238 | TPK1 | 0.33 | 6.2E-19 |
| Kyung WK | 32795589 | DNA methylation | atopy | nasal polyp | discovery | 108 | cg02953520 | chr7:144347613 | TPK1 | -0.011 | 2.3E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | 0.072 | 3.1E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.072 | 3.6E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg03626985 | chr7:144435539 | TPK1 | 0.071 | 5.7E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | -0.0710233 | 7.1E-18 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0702341 | 1.6E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.069 | 5.8E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.069 | 6.2E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | 0.069 | 6.7E-17 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg06847417 | chr7:144515907 | TPK1 | -0.246362 | 8E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg26606600 | chr7:144232092 | TPK1 | 0.069 | 9.4E-17 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg15154051 | chr7:144483814 | TPK1 | 0.067 | 7.4E-16 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3077766 (gene symbol: TPK1) | Whole blood | Meta-analysis | 4170 | cg18992848 | chr7:144531951 | TPK1 | NA | 7.8E-16 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.066 | 9E-16 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg18956562 | chr7:144149304 | TPK1 | 0.043 | 2.1E-15 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0650687 | 3E-15 |
| Xu CJ | 28056824 | DNA methylation | Age 4 vs age 0 | Whole blood and cord blood | - | 269 | cg01832012 | chr7:144437395 | TPK1 | NA | 6.5E-15 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg02953520 | chr7:144347613 | TPK1 | -0.00031 | 1E-14 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg02641052 | chr7:144531399 | TPK1 | -0.00066 | 1.6E-14 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg26602666 | chr7:144380035 | TPK1 | 0.055 | 1.8E-14 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg11183253 | chr7:144347841 | TPK1 | -2.490967 | 1.9E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.063 | 2.7E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | -0.0626847 | 3E-14 |
| Kyung WK | 32795589 | DNA methylation | eosinophilia | nasal polyp | discovery | 129 | cg15454151 | chr7:144527352 | TPK1 | -0.024 | 5.8E-14 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01345827 | chr7:144532382 | TPK1 | -0.0003 | 6.6E-14 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.061 | 1.2E-13 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg07811915 | chr7:144509662 | TPK1 | 0.028 | 1.3E-13 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.061 | 1.3E-13 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg06847417 | chr7:144515907 | TPK1 | -0.219129 | 1.4E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.061 | 1.7E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.061 | 1.7E-13 |
| Dugue PA | 31552803 | DNA methylation | Smoking | Whole blood | Current vs never smoking | 1851 | cg18956562 | chr7:144149304 | TPK1 | 0.15 | 1.9E-13 |
| Kyung WK | 32795589 | DNA methylation | atopy | nasal polyp | discovery | 108 | cg15454151 | chr7:144527352 | TPK1 | -0.024 | 2E-13 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg21370481 | chr7:144533376 | TPK1 | -0.0012 | 2.5E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg12635404 | chr7:144226807 | TPK1 | 0.06 | 3.1E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.059 | 5.8E-13 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.059 | 6.5E-13 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0588164 | 1E-12 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg07612045 | chr7:144533234 | TPK1 | 0.01 | 2E-12 |
| Joehanes R | 27651444 | DNA methylation | Current versus never smoking | Whole blood, CD4+ T cells or monocytes | Current vs never smoking | 9389 | cg18956562 | chr7:144149304 | TPK1 | 0.013 | 2E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.059 | 2.3E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.058 | 3E-12 |
| Yao C | 33752734 | DNA methylation | Gene expression of Affymetrix ID: 3077766 (gene symbol: TPK1) | Whole blood | Meta-analysis | 4170 | cg21370481 | chr7:144533376 | TPK1 | NA | 3.9E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg21370481 | chr7:144533376 | TPK1 | -0.13309 | 4E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg22315684 | chr7:144210744 | TPK1 | 0.24 | 4.4E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.057 | 5.4E-12 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg00201968 | chr7:144354238 | TPK1 | 2.6 | 6.4E-12 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.056 | 9.3E-12 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg00201968 | chr7:144354238 | TPK1 | 0.28 | 1.1E-11 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0558421 | 1.3E-11 |
| Joehanes R | 27651444 | DNA methylation | Former versus never smoking | Whole blood, CD4+ T cells or monocytes | Former vs never smoking | 13474 | cg18956562 | chr7:144149304 | TPK1 | 0.0059 | 1.6E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg21370481 | chr7:144533376 | TPK1 | -0.12896 | 2E-11 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg07811915 | chr7:144509662 | TPK1 | 1.5 | 3.9E-11 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg21370481 | chr7:144533376 | TPK1 | 0.0069 | 8.9E-11 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg00201968 | chr7:144354238 | TPK1 | 0.24 | 1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.053 | 1.1E-10 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.053 | 1.5E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0525655 | 1.9E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg26606600 | chr7:144232092 | TPK1 | 0.052 | 2.1E-10 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg21690631 | chr7:144368888 | TPK1 | -0.02138 | 2.2E-10 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg22315684 | chr7:144210744 | TPK1 | 0.22 | 2.3E-10 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg08599300 | chr7:144533232 | TPK1 | 0.0074 | 3.6E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.052 | 4.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.052 | 4.3E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg23307858 | chr7:144533454 | TPK1 | -0.0513261 | 5E-10 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | -0.0510931 | 5.9E-10 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg21073826 | chr7:144273837 | TPK1 | NA | 6.2E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.051 | 6.4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | 0.051 | 7.5E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.051 | 9.4E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | -0.0504444 | 9.8E-10 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | -0.0502482 | 1.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg03626985 | chr7:144435539 | TPK1 | 0.05 | 1.2E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.05 | 1.3E-09 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg06550309 | chr7:144533283 | TPK1 | 2.0 | 1.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 2 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0535181 | 1.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg02641052 | chr7:144531399 | TPK1 | -0.0494526 | 2.1E-09 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg26602666 | chr7:144380035 | TPK1 | NA | 2.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.049 | 2.7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0764952 | 3.1E-09 |
| Christiansen C | 33593402 | DNA methylation | Smoking | Whole blood | Current vs never smoking meta-analysis in European samples | 912 | cg18956562 | chr7:144149304 | TPK1 | NA | 3.2E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg07612045 | chr7:144533234 | TPK1 | 0.00018 | 3.7E-09 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg14468856 | chr7:144437456 | TPK1 | 0.035 | 4.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg26606600 | chr7:144232092 | TPK1 | 0.048 | 4.6E-09 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01173941 | chr7:144262949 | TPK1 | -0.00051 | 4.9E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0482367 | 5E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 2 | 14671 | cg18956562 | chr7:144149304 | TPK1 | 0.048 | 5.8E-09 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Lung Cancer | Whole blood | Basic model | 18364 | cg18956562 | chr7:144149304 | TPK1 | 0.017 | 5.8E-09 |
| Kashima K | 33564054 | DNA methylation | gestational age | Cord blood | None | 110 | cg01832012 | chr7:144437395 | TPK1 | -0.0065 | 6.1E-09 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | -0.0479313 | 6.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.048 | 7E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg09961998 | chr7:144417304 | TPK1 | -0.0477746 | 7.1E-09 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg18119299 | chr7:144532562 | TPK1 | 1.4 | 9.3E-09 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.047 | 1E-08 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg16886395 | chr7:144363836 | TPK1 | -1.8 | 1.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.047002 | 1.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.047 | 1.3E-08 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg00201968 | chr7:144354238 | TPK1 | 0.1 | 1.3E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.047 | 1.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0464539 | 1.8E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | sensitivity | 17304 | cg06847417 | chr7:144515907 | TPK1 | -0.171522 | 1.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | -0.0464464 | 1.8E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg23307858 | chr7:144533454 | TPK1 | -0.151392 | 2E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg02641052 | chr7:144531399 | TPK1 | 0.0006 | 2.1E-08 |
| Li M | 33279932 | DNA methylation | Schizophrenia | Whole blood | main | 999 | cg21690631 | chr7:144368888 | TPK1 | -0.01108 | 2.2E-08 |
| Li M | 33279932 | DNA methylation | Schizophrenia | Whole blood | adjusted for cell composition | 999 | cg21690631 | chr7:144368888 | TPK1 | NA | 2.3E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg26602666 | chr7:144380035 | TPK1 | -0.0021 | 2.3E-08 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg09268854 | chr7:144436437 | TPK1 | -2.0 | 2.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.047 | 2.6E-08 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg23307858 | chr7:144533454 | TPK1 | -0.149227 | 2.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg15154051 | chr7:144483814 | TPK1 | 0.046 | 3.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.046 | 3.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0455082 | 3.5E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg26602666 | chr7:144380035 | TPK1 | -0.03717 | 3.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.045 | 3.8E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.045 | 3.9E-08 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg21073826 | chr7:144273837 | TPK1 | -0.0018 | 4.4E-08 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg13120875 | chr7:144533471 | TPK1 | 0.015 | 4.5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg25105147 | chr7:144474743 | TPK1 | -0.0450761 | 4.7E-08 |
| Liu Y | 23334450 | DNA methylation | Rheumatoid arthritis | Whole blood | - | 691 | cg06018711 | chr7:144352927 | TPK1 | -0.02686 | 4.8E-08 |
| Imgenberg-Kreuz J | 26857698 | DNA methylation | Primary Sjogrens syndrome | Whole blood | Whole blood | 500 | cg16316507 | chr7:144533041 | TPK1 | NA | 4.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg23307858 | chr7:144533454 | TPK1 | -0.0449771 | 5E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0449219 | 5.2E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 2 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0702391 | 5.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 3 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0449867 | 5.9E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | 0.045 | 6.1E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0446152 | 6.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.045 | 8.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 1 | 14671 | cg09268854 | chr7:144436437 | TPK1 | -0.044218 | 8.4E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 1 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0441767 | 8.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg15154051 | chr7:144483814 | TPK1 | 0.055 | 9.6E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0440122 | 9.7E-08 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg03626985 | chr7:144435539 | TPK1 | -0.0438773 | 1.1E-07 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg02953520 | chr7:144347613 | TPK1 | -1.562165 | 1.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg02641052 | chr7:144531399 | TPK1 | 0.043 | 1.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg26606600 | chr7:144232092 | TPK1 | 0.043 | 1.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0435807 | 1.6E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg15972370 | chr7:144422234 | TPK1 | -0.0018 | 1.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 2 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.067 | 2E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg00201968 | chr7:144354238 | TPK1 | 0.19 | 2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | -0.0427253 | 2.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg18956562 | chr7:144149304 | TPK1 | -0.0428865 | 2.3E-07 |
| Christiansen C | 33593402 | DNA methylation | Smoking | Whole blood | Current vs never smoking meta-analysis in European samples | 912 | cg07811915 | chr7:144509662 | TPK1 | NA | 2.4E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | sensitivity | 18225 | cg06847417 | chr7:144515907 | TPK1 | 0.15 | 2.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.042 | 2.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.042 | 3.1E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0421298 | 3.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.042 | 3.4E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0431177 | 3.5E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg09268854 | chr7:144436437 | TPK1 | 0.042 | 3.6E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg14506793 | chr7:144436515 | TPK1 | -0.264863 | 3.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.042 | 3.7E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg01204439 | chr7:144533322 | TPK1 | 0.00058 | 4E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg16316507 | chr7:144533041 | TPK1 | 0.15 | 4.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg02641052 | chr7:144531399 | TPK1 | 0.041 | 5.3E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0410403 | 6.6E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg01832012 | chr7:144437395 | TPK1 | -0.0410291 | 6.7E-07 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg16316507 | chr7:144533041 | TPK1 | 0.0026 | 6.7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.041 | 6.8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | 0.041 | 6.9E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg26606600 | chr7:144232092 | TPK1 | -0.132293 | 7E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | -0.0409092 | 7.2E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0408295 | 7.5E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg02641052 | chr7:144531399 | TPK1 | -0.199056 | 8E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.041 | 8.9E-07 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | -0.0404694 | 9.4E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg06847417 | chr7:144515907 | TPK1 | -0.144875 | 9.6E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg21370481 | chr7:144533376 | TPK1 | -0.108476 | 9.8E-07 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg22315684 | chr7:144210744 | TPK1 | 0.17 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P29622 | whole blood | OSCA model 1 | 14671 | cg23307858 | chr7:144533454 | TPK1 | 0.04 | 1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0402383 | 1.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01024 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0401848 | 1.1E-06 |
| Darina Czamara | 38600394 | DNA methylation | sex | placenta | meta-analysis of robust linear regression results per cohort | 746 | cg14468856 | chr7:144437456 | TPK1 | 0.1 | 1.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg18956562 | chr7:144149304 | TPK1 | -0.0399657 | 1.3E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg06847417 | chr7:144515907 | TPK1 | 0.14 | 1.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 1 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0399102 | 1.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.04 | 1.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg25105147 | chr7:144474743 | TPK1 | -0.0397755 | 1.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0397338 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01619 | whole blood | OSCA model 1 | 14671 | cg09268854 | chr7:144436437 | TPK1 | -0.0397107 | 1.5E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg19714749 | chr7:144533092 | TPK1 | 0.0052 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg18992848 | chr7:144531951 | TPK1 | 0.04 | 1.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.039647 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 2 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0399406 | 1.6E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg00201968 | chr7:144354238 | TPK1 | 0.2 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 2 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0425694 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 3 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0398353 | 1.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg15154051 | chr7:144483814 | TPK1 | -0.0395513 | 1.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0405775 | 1.8E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg15454151 | chr7:144527352 | TPK1 | -0.1238 | 1.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | -0.0392297 | 2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0402534 | 2.2E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | discovery | 17304 | cg14453876 | chr7:144518505 | TPK1 | -0.113217 | 2.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0389319 | 2.4E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg16316507 | chr7:144533041 | TPK1 | 0.00038 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | O75636 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0388939 | 2.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q99459 | whole blood | OSCA model 1 | 14671 | cg09268854 | chr7:144436437 | TPK1 | -0.0388216 | 2.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02671 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | 0.039 | 2.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0387226 | 2.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.039 | 2.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 2 | 14671 | cg03626985 | chr7:144435539 | TPK1 | 0.041 | 2.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.039 | 2.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.039 | 2.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 2 | 14671 | cg15154051 | chr7:144483814 | TPK1 | -0.0398417 | 3E-06 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Whole blood | Discovery | 181 | cg07612045 | chr7:144533234 | TPK1 | 1.1 | 3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00747 | whole blood | OSCA model 3 | 14671 | cg15154051 | chr7:144483814 | TPK1 | -0.039747 | 3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 3 | 14671 | cg03626985 | chr7:144435539 | TPK1 | 0.041 | 3.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.038 | 3.1E-06 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg21690631 | chr7:144368888 | TPK1 | 0.0038 | 3.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH35 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0394307 | 3.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0382025 | 3.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.039 | 3.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0381633 | 3.8E-06 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg26606600 | chr7:144232092 | TPK1 | -1.2 | 3.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | -0.0380862 | 3.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.038086 | 3.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | -0.037965 | 4.2E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg11183253 | chr7:144347841 | TPK1 | 0.0021 | 4.6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg25105147 | chr7:144474743 | TPK1 | -0.0377907 | 4.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 2 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0495686 | 4.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg25105147 | chr7:144474743 | TPK1 | 0.038 | 5.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0376312 | 5.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg03626985 | chr7:144435539 | TPK1 | -0.0376104 | 5.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0375574 | 5.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.038 | 5.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg26606600 | chr7:144232092 | TPK1 | 0.038 | 5.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 2 | 14671 | cg01832012 | chr7:144437395 | TPK1 | -0.0388637 | 5.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | -0.0374101 | 5.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg25105147 | chr7:144474743 | TPK1 | 0.037 | 5.9E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a fixed effect | 2338 | cg21073826 | chr7:144273837 | TPK1 | -0.0097 | 6E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 2 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.049 | 6.1E-06 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg14468856 | chr7:144437456 | TPK1 | 0.0036 | 6.4E-06 |
| Dugue PA | 31552803 | DNA methylation | Smoking | Whole blood | Former vs never smoking | 156 | cg18956562 | chr7:144149304 | TPK1 | 0.06 | 6.8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01031 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.037 | 7E-06 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg14506793 | chr7:144436515 | TPK1 | -0.235323 | 7.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.037 | 7.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0A0MT89 | whole blood | OSCA model 1 | 14671 | cg09268854 | chr7:144436437 | TPK1 | -0.0369702 | 7.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg18956562 | chr7:144149304 | TPK1 | 0.037 | 7.8E-06 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg11183253 | chr7:144347841 | TPK1 | 0.008 | 8E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 3 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0361862 | 8.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0367955 | 8.3E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 3 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0573218 | 8.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg16886395 | chr7:144363836 | TPK1 | 0.037 | 8.7E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 3 | 14671 | cg03626985 | chr7:144435539 | TPK1 | -0.03809 | 9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0366185 | 9.1E-06 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0366161 | 9.2E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0365658 | 9.4E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0365437 | 9.5E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 1 | 14671 | cg01173941 | chr7:144262949 | TPK1 | 0.037 | 9.7E-06 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Fully-adjusted model | 14040 | cg09268854 | chr7:144436437 | TPK1 | -1.6 | 9.9E-06 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.048 | 1E-05 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg15972370 | chr7:144422234 | TPK1 | 0.049 | 1E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg19735335 | chr7:144532933 | TPK1 | -8e-05 | 1E-05 |
| Mulder RH | 33450751 | DNA methylation | sex | Whole blood | Discovery | 2338 | cg08599300 | chr7:144533232 | TPK1 | -0.00073 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01780 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0373623 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08571 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0362725 | 1.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04217 | whole blood | OSCA model 1 | 14671 | cg16886395 | chr7:144363836 | TPK1 | 0.036 | 1.2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg21370481 | chr7:144533376 | TPK1 | -0.0964233 | 1.2E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Prevalent COPD (Self-report) | Whole blood | Basic model | 18078 | cg18956562 | chr7:144149304 | TPK1 | 0.041 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.036 | 1.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.036 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg26606600 | chr7:144232092 | TPK1 | -0.0359623 | 1.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | discovery | 17304 | cg02641052 | chr7:144531399 | TPK1 | -0.176082 | 1.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 3 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0361706 | 1.4E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg22315684 | chr7:144210744 | TPK1 | 0.15 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 2 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0360903 | 1.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 3 | 14671 | cg01832012 | chr7:144437395 | TPK1 | -0.0370388 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 2 | 14671 | cg09268854 | chr7:144436437 | TPK1 | -0.038079 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02647 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0357299 | 1.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg15154051 | chr7:144483814 | TPK1 | 0.036 | 1.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01780 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0355899 | 1.6E-05 |
| Battram T | 30602389 | DNA methylation | Tissue | Buccal cells and peripheral blood mononuclear cells | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells | 215 | cg08599300 | chr7:144533232 | TPK1 | 0.0051 | 1.7E-05 |
| Robert F. Hillary | doi.org/10.1101/2023.11.02.23298000 | C-reactive protein (CRP) levels | DNA methylation | Whole blood | Basic model | 17936 | cg20163964 | chr7:144367606 | TPK1 | 0.73 | 1.7E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Neutrophils | Neutrophils | 60 | cg23307858 | chr7:144533454 | TPK1 | -0.304097 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 2 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0357126 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 1 | 14671 | cg01832012 | chr7:144437395 | TPK1 | -0.0354545 | 1.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0354059 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 2 | 14671 | cg03626985 | chr7:144435539 | TPK1 | -0.0376431 | 1.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 3 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0544961 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P05546 | whole blood | OSCA model 2 | 14671 | cg09268854 | chr7:144436437 | TPK1 | -0.0375733 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 3 | 14671 | cg12513254 | chr7:144435937 | TPK1 | -0.0350335 | 1.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P20742 | whole blood | OSCA model 4 | 14671 | cg12635404 | chr7:144226807 | TPK1 | 0.037 | 1.9E-05 |
| Gross AM | 27105112 | DNA methylation | HIV infection | Neutrophils | Neutrophils | 60 | cg13120875 | chr7:144533471 | TPK1 | -0.237271 | 2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Body fat | Whole blood | sensitivity | 17304 | cg18992848 | chr7:144531951 | TPK1 | -0.0773979 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.036 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 2 | 14671 | cg12513254 | chr7:144435937 | TPK1 | -0.0358418 | 2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | sensitivity | 17304 | cg22315684 | chr7:144210744 | TPK1 | 0.15 | 2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 3 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.055 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P55056 | whole blood | OSCA model 1 | 14671 | cg02641052 | chr7:144531399 | TPK1 | -0.0351065 | 2.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg25105147 | chr7:144474743 | TPK1 | -0.0350574 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43251 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.035 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg03182504 | chr7:144532459 | TPK1 | 0.035 | 2.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH38 | whole blood | OSCA model 4 | 14671 | cg09268854 | chr7:144436437 | TPK1 | -0.0400485 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | O75882 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0349086 | 2.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 1 | 14671 | cg18956562 | chr7:144149304 | TPK1 | 0.035 | 2.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 4 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0579188 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg07612045 | chr7:144533234 | TPK1 | 0.035 | 2.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B6I1 | whole blood | OSCA model 1 | 14671 | cg06847417 | chr7:144515907 | TPK1 | 0.035 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0G2JMB2 | whole blood | OSCA model 2 | 14671 | cg18956562 | chr7:144149304 | TPK1 | 0.035 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04275 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0347169 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | 0.035 | 2.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.035 | 2.8E-05 |
| Battram T | 25424692 | DNA methylation | Smoking | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE50660. Never vs former smokers | 442 | cg18956562 | chr7:144149304 | TPK1 | -0.015 | 2.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 3 | 14671 | cg22315684 | chr7:144210744 | TPK1 | -0.0519837 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0354872 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg03626985 | chr7:144435539 | TPK1 | 0.034 | 3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg12635404 | chr7:144226807 | TPK1 | 0.034 | 3.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q13790 | whole blood | OSCA model 2 | 14671 | cg15379825 | chr7:144530726 | TPK1 | -0.0344596 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01008 | whole blood | OSCA model 2 | 14671 | cg21370481 | chr7:144533376 | TPK1 | 0.035 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg03626985 | chr7:144435539 | TPK1 | 0.037 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P51884 | whole blood | OSCA model 1 | 14671 | cg25105147 | chr7:144474743 | TPK1 | 0.034 | 3.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A075B7B8 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0352424 | 3.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 1 | 14671 | cg14506793 | chr7:144436515 | TPK1 | -0.0341782 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00734 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0341704 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg23307858 | chr7:144533454 | TPK1 | -0.034161 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 2 | 14671 | cg15483426 | chr7:144436028 | TPK1 | 0.034 | 3.5E-05 |
| Gadd DA | 35945220 | FCGR2A protein levels (SeqId = 3309-2) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg00201968 | chr7:144354238 | TPK1 | 0.81 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg03626985 | chr7:144435539 | TPK1 | 0.034 | 3.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 1 | 14671 | cg14468856 | chr7:144437456 | TPK1 | -0.034125 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02751 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | -0.0341172 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P36955 | whole blood | OSCA model 3 | 14671 | cg16886395 | chr7:144363836 | TPK1 | 0.036 | 3.6E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg09268854 | chr7:144436437 | TPK1 | -0.028 | 3.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q13790 | whole blood | OSCA model 1 | 14671 | cg15379825 | chr7:144530726 | TPK1 | -0.0340599 | 3.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 1 | 14671 | cg25105147 | chr7:144474743 | TPK1 | -0.034017 | 3.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 2 | 14671 | cg12513254 | chr7:144435937 | TPK1 | -0.0346561 | 3.8E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | BMI | Whole blood | sensitivity | 17304 | cg18992848 | chr7:144531951 | TPK1 | -0.0741913 | 3.8E-05 |
| Gadd DA | 35945220 | TMEM132C protein levels (SeqId = 7173-141) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg22315684 | chr7:144210744 | TPK1 | -0.75 | 3.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 2 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.053 | 4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 1 | 14671 | cg12513254 | chr7:144435937 | TPK1 | -0.0338696 | 4.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P14151 | whole blood | OSCA model 3 | 14671 | cg18956562 | chr7:144149304 | TPK1 | -0.0340414 | 4.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01019 | whole blood | OSCA model 3 | 14671 | cg12513254 | chr7:144435937 | TPK1 | -0.0343378 | 4.3E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg22315684 | chr7:144210744 | TPK1 | 0.14 | 4.3E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 6y with age as a fixed effect | 2338 | cg14268194 | chr7:144226107 | TPK1 | -0.0097 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | -0.0337112 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P35858 | whole blood | OSCA model 2 | 14671 | cg01832012 | chr7:144437395 | TPK1 | -0.0349445 | 4.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 1 | 14671 | cg16886395 | chr7:144363836 | TPK1 | 0.034 | 4.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 4 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.035 | 4.6E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg15154051 | chr7:144483814 | TPK1 | -0.031 | 4.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 3 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0347435 | 4.7E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | discovery | 17304 | cg21370481 | chr7:144533376 | TPK1 | -0.0780369 | 4.7E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Ischemic Heart Disease | Whole blood | Fully-adjusted model | 13797 | cg25105147 | chr7:144474743 | TPK1 | 0.032 | 4.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02750 | whole blood | OSCA model 3 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.034 | 4.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg02641052 | chr7:144531399 | TPK1 | -0.0335504 | 4.8E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident Ischemic Heart Disease | Whole blood | Basic model | 17483 | cg18956562 | chr7:144149304 | TPK1 | 0.025 | 5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 4 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0352895 | 5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06310 | whole blood | OSCA model 1 | 14671 | cg26606600 | chr7:144232092 | TPK1 | -0.0334204 | 5.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0C4DH35 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.0334178 | 5.2E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | HDL cholesterol | Whole blood | discovery | 18225 | cg26606600 | chr7:144232092 | TPK1 | 0.1 | 5.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08185 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.033 | 5.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A087WSY6 | whole blood | OSCA model 1 | 14671 | cg25105147 | chr7:144474743 | TPK1 | 0.033 | 5.3E-05 |
| Gadd DA | 35945220 | LY9 protein levels (SeqId = 3324-51) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg09268854 | chr7:144436437 | TPK1 | -0.8 | 5.4E-05 |
| Bohlin J | 27717397 | DNA methylation | Gestational age | Cord blood | Last menstrual period-estimated gestational age | 1068 | cg13120875 | chr7:144533471 | TPK1 | -0.00010279 | 5.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg15154051 | chr7:144483814 | TPK1 | 0.034 | 5.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q96PD5 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.033 | 5.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 3 | 14671 | cg15483426 | chr7:144436028 | TPK1 | 0.034 | 5.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.034 | 5.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 3 | 14671 | cg18956562 | chr7:144149304 | TPK1 | 0.033 | 5.6E-05 |
| Priyanka Choudhary | 38052982 | DNA methylation | Maternal education at the time of pregnancy | Whole blood | Model1_Childhood | 2017 | cg21690631 | chr7:144368888 | TPK1 | 0.0004 | 5.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg01832012 | chr7:144437395 | TPK1 | -0.0332228 | 5.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06727 | whole blood | OSCA model 1 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.033 | 5.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg15454151 | chr7:144527352 | TPK1 | -0.0331902 | 5.8E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a fixed effect | 2338 | cg03182504 | chr7:144532459 | TPK1 | -9.2e-05 | 5.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 1 | 14671 | cg14468856 | chr7:144437456 | TPK1 | -0.0331161 | 6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 4 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.034 | 6.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | Q9BXR6 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.033 | 6.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 2 | 14671 | cg06847417 | chr7:144515907 | TPK1 | 0.035 | 6.2E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P06396 | whole blood | OSCA model 2 | 14671 | cg09268854 | chr7:144436437 | TPK1 | 0.035 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04114 | whole blood | OSCA model 1 | 14671 | cg16886395 | chr7:144363836 | TPK1 | -0.0330366 | 6.3E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 2 at 9y with age as a random effect | 2338 | cg02641052 | chr7:144531399 | TPK1 | 0.0018 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02763 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.033 | 6.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01766 | whole blood | OSCA model 1 | 14671 | cg09268854 | chr7:144436437 | TPK1 | -0.0330107 | 6.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P18428 | whole blood | OSCA model 2 | 14671 | cg09268854 | chr7:144436437 | TPK1 | -0.0348422 | 6.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | A0A0B4J1V0 | whole blood | OSCA model 1 | 14671 | cg07811915 | chr7:144509662 | TPK1 | -0.032953 | 6.5E-05 |
| Robert F Hillary | 10.1101/2023.01.10.23284387 | DNA methylation | Incident COPD | Whole blood | Basic model | 17902 | cg03626985 | chr7:144435539 | TPK1 | -0.017 | 6.6E-05 |
| Battram T | 24603599 | DNA methylation | Frontotemporal dementia | Whole blood | EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE53740 | 314 | cg16316507 | chr7:144533041 | TPK1 | -0.006 | 6.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg12635404 | chr7:144226807 | TPK1 | 0.033 | 6.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00740 | whole blood | OSCA model 2 | 14671 | cg15154051 | chr7:144483814 | TPK1 | -0.0339146 | 6.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04003 | whole blood | OSCA model 1 | 14671 | cg02641052 | chr7:144531399 | TPK1 | -0.0328379 | 6.9E-05 |
| Gadd DA | 35945220 | GZMA protein levels (SeqId = 3440-7) | DNA methylation | Whole blood | SomaScan protein measurement | 774 | cg09268854 | chr7:144436437 | TPK1 | -0.79 | 7.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg15154051 | chr7:144483814 | TPK1 | -0.0337205 | 7.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg26606600 | chr7:144232092 | TPK1 | 0.033 | 7.5E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Total cholesterol | Whole blood | discovery | 18270 | cg22315684 | chr7:144210744 | TPK1 | 0.13 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P00450 | whole blood | OSCA model 1 | 14671 | cg25105147 | chr7:144474743 | TPK1 | -0.0326662 | 7.6E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02649 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.033 | 7.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P08603 | whole blood | OSCA model 2 | 14671 | cg07811915 | chr7:144509662 | TPK1 | 0.034 | 7.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01742 | whole blood | OSCA model 1 | 14671 | cg26606600 | chr7:144232092 | TPK1 | 0.033 | 7.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg01832012 | chr7:144437395 | TPK1 | -0.0325631 | 8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | 0.033 | 8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04196 | whole blood | OSCA model 3 | 14671 | cg22315684 | chr7:144210744 | TPK1 | 0.051 | 8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P43652 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | -0.0324896 | 8.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02775 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0324791 | 8.3E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02790 | whole blood | OSCA model 1 | 14671 | cg16886395 | chr7:144363836 | TPK1 | 0.032 | 8.4E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg15379825 | chr7:144530726 | TPK1 | 0.0016 | 8.7E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01834 | whole blood | OSCA model 1 | 14671 | cg26606600 | chr7:144232092 | TPK1 | -0.0323577 | 8.9E-05 |
| Hannah M. Smith | 39706196 | DNA methylation | Waist-hip ratio | Whole blood | sensitivity | 17304 | cg14506793 | chr7:144436515 | TPK1 | -0.204833 | 8.9E-05 |
| Kazmi N | 31230546 | DNA methylation | Hypertensive disorders of pregnancy | Cord blood | Meta analysis adjusted model | 5242 | cg26602666 | chr7:144380035 | TPK1 | 0.0097 | 8.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | -0.0323064 | 9.1E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 4 | 14671 | cg12635404 | chr7:144226807 | TPK1 | 0.033 | 9.2E-05 |
| Joubert BR | 27040690 | DNA methylation | Maternal smoking in pregnancy | Cord blood | Any maternal smoking in pregnancy effect on newborns | 6685 | cg01832012 | chr7:144437395 | TPK1 | 0.006 | 9.4E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P25311 | whole blood | OSCA model 1 | 14671 | cg00201968 | chr7:144354238 | TPK1 | -0.0322282 | 9.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P27169 | whole blood | OSCA model 2 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0324471 | 9.5E-05 |
| Dugue P-A | 31789449 | Alcohol consumption | DNA methylation | Whole blood | Previous week consumption discovery | 5606 | cg01832012 | chr7:144437395 | TPK1 | NA | 9.5E-05 |
| Mulder RH | 33450751 | DNA methylation | age | Whole blood | Model 1 with age as a random effect | 2338 | cg01832012 | chr7:144437395 | TPK1 | 0.0018 | 9.5E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01023 | whole blood | OSCA model 1 | 14671 | cg15483426 | chr7:144436028 | TPK1 | 0.032 | 9.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P04004 | whole blood | OSCA model 2 | 14671 | cg06847417 | chr7:144515907 | TPK1 | -0.0345428 | 9.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P02748 | whole blood | OSCA model 2 | 14671 | cg18956562 | chr7:144149304 | TPK1 | 0.032 | 9.8E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P01042 | whole blood | OSCA model 1 | 14671 | cg15483426 | chr7:144436028 | TPK1 | -0.0321406 | 9.9E-05 |
| Josephine Robertson | 41361833 | DNA methylation | P10643 | whole blood | OSCA model 1 | 14671 | cg14453876 | chr7:144518505 | TPK1 | 0.032 | 9.9E-05 |
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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.
