EWAS Catalog β

The MRC-IEU catalog of epigenome-wide association studies

Search results for TXNIP

 

Author PMID Outcome Exposure Tissue Analysis N CpG Location Gene Beta P
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg10713626 chr1:145438766 TXNIP -0.0013 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg19693031 chr1:145441552 TXNIP -0.0036 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 6y with age as a fixed effect 2338 cg19693031 chr1:145441552 TXNIP 0.012 0E+00
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Discovery and replication 3187 cg19693031 chr1:145441552 TXNIP -0.039 0E+00
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Discovery and replication adjusted for surrogate variables 3187 cg19693031 chr1:145441552 TXNIP -0.049 0E+00
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg22619763 chr1:145438623 TXNIP -0.0026 0E+00
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood sensitivity 17908 cg19693031 chr1:145441552 TXNIP -0.538279 2.9E-86
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Basic model 18005 cg19693031 chr1:145441552 TXNIP -0.22 1.6E-81
Hannah M. Smith 39706196 DNA methylation Glucose Whole blood discovery 17908 cg19693031 chr1:145441552 TXNIP -0.46722 2.1E-74
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.133925 1.1E-59
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood sensitivity 17304 cg19693031 chr1:145441552 TXNIP -0.435949 2E-57
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.135113 6.8E-57
Bonder MJ 25282492 DNA methylation Fetal vs adult liver Liver - 195 cg19693031 chr1:145441552 TXNIP 3.9 5.2E-56
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19693031 chr1:145441552 TXNIP -0.15415 2.7E-55
Hannah M. Smith 39706196 DNA methylation BMI Whole blood sensitivity 17304 cg19693031 chr1:145441552 TXNIP -0.42411 4.2E-55
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.14 1.4E-53
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Prevalent Type 2 Diabetes (Self-report) Whole blood Fully-adjusted model 14350 cg19693031 chr1:145441552 TXNIP -0.19 1.8E-53
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.133733 2.7E-51
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.139314 3.3E-51
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood sensitivity 17304 cg19693031 chr1:145441552 TXNIP -0.407625 9.8E-51
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.123153 1.1E-50
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.12 1.8E-44
Josephine Robertson 41361833 DNA methylation P04004 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.114171 5.4E-44
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.117703 3.1E-43
Josephine Robertson 41361833 DNA methylation P01042 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.117106 4.7E-43
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.11 3.2E-42
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.11 9E-42
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.111672 2.3E-39
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Basic model 17749 cg19693031 chr1:145441552 TXNIP -0.069 8.7E-38
Josephine Robertson 41361833 DNA methylation P02748 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.11 1E-37
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.11 1.1E-36
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.103833 1.9E-36
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.10642 1.1E-35
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.115109 1.3E-35
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.105789 1.5E-35
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.103216 1.2E-33
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.099 4.1E-32
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.106616 6.4E-32
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg19693031 chr1:145441552 TXNIP -0.300572 2.5E-31
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0954691 4.7E-31
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0949579 9.7E-31
Richard MA 29198723 DNA methylation Systolic Blood Pressure Whole blood, CD4+ T cells Meta-analysis 17010 cg19693031 chr1:145441552 TXNIP -0.0002 3.1E-29
Josephine Robertson 41361833 DNA methylation P01834 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.1 6.6E-29
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.10303 7E-29
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood sensitivity 18270 cg19693031 chr1:145441552 TXNIP -0.294752 8.4E-29
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.091 1.8E-28
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.091 1.9E-28
Hannah M. Smith 39706196 DNA methylation Waist-hip ratio Whole blood discovery 17304 cg19693031 chr1:145441552 TXNIP -0.284133 2.5E-28
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0895662 1.6E-27
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.089 1.9E-27
Josephine Robertson 41361833 DNA methylation P43652 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0893409 9.9E-27
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Replication adjusted for surrogate variables 2542 cg19693031 chr1:145441552 TXNIP -0.051 5.7E-26
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0885791 3.8E-25
Hannah M. Smith 39706196 DNA methylation BMI Whole blood discovery 17304 cg19693031 chr1:145441552 TXNIP -0.262867 2E-24
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg19693031 chr1:145441552 TXNIP 0.0024 2.6E-24
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.084 2.9E-24
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.086 8.3E-24
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.085759 9.1E-24
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0917359 3.3E-23
Hannah M. Smith 39706196 DNA methylation Total cholesterol Whole blood discovery 18270 cg19693031 chr1:145441552 TXNIP -0.246457 3.6E-23
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.083 1.2E-22
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.083 1.5E-22
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0834699 1.6E-22
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.083 2E-22
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0802534 2.1E-22
Robert F Hillary 10.1101/2023.01.10.23284387 DNA methylation Incident Type 2 Diabetes Whole blood Fully-adjusted model 13971 cg19693031 chr1:145441552 TXNIP -0.056 2.2E-22
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0799612 3E-22
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.08 3.2E-22
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.082 8.6E-22
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0789545 1E-21
Petersen A-K 24014485 M35186_1-arachidonoylglycerophosphoethanolamine* DNA methylation Whole blood snps as covariates model 1760 cg19693031 chr1:145441552 TXNIP -1.0 1.1E-21
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.087 1.2E-21
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous week consumption discovery 5606 cg19693031 chr1:145441552 TXNIP NA 1.4E-21
Cardona A 31506343 DNA methylation Type II diabetes Whole blood Replication in Europeans 2607 cg19693031 chr1:145441552 TXNIP -0.026 1.6E-21
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.081 2.1E-21
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0878136 2.2E-21
Cardona A 31506343 Type II diabetes DNA methylation Whole blood Discovery 1264 cg19693031 chr1:145441552 TXNIP -0.65 2.7E-21
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.081 3.1E-21
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0876166 4.2E-21
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0804891 4.7E-21
Petersen A-K 24014485 M35186_1-arachidonoylglycerophosphoethanolamine* DNA methylation Whole blood no snps model 1760 cg19693031 chr1:145441552 TXNIP -1.0 8.9E-21
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0770532 9.1E-21
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0769976 9.7E-21
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Replication 2542 cg19693031 chr1:145441552 TXNIP -0.041 1E-20
Josephine Robertson 41361833 DNA methylation P06312 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.086 1E-20
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.085 1.4E-20
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.079 1.6E-20
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.078 4.1E-20
Josephine Robertson 41361833 DNA methylation P01019 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0783627 4.4E-20
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0712177 5.3E-20
Josephine Robertson 41361833 DNA methylation O75636 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0775974 7.2E-20
Josephine Robertson 41361833 DNA methylation P01024 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0760687 1.6E-19
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0739853 2.9E-19
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.074 4.3E-19
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.075 4.4E-19
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.076 4.9E-19
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Previous decade consumption discovery 5606 cg19693031 chr1:145441552 TXNIP NA 5.2E-19
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery and replication 4261 cg19693031 chr1:145441552 TXNIP -0.0141941 5.7E-19
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Basic model 17936 cg19693031 chr1:145441552 TXNIP -1.5 7.5E-19
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0806823 7.8E-19
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.073 8.4E-19
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.082 9.1E-19
Chambers JC 26095709 Type II diabetes DNA methylation Peripheral blood Meta-analysis 3805 cg19693031 chr1:145441552 TXNIP -0.0834 1.5E-18
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0749323 1.6E-18
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0749243 1.7E-18
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.072 1.8E-18
Josephine Robertson 41361833 DNA methylation P55056 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0746227 2.6E-18
Josephine Robertson 41361833 DNA methylation A0A0C4DH35 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.08 3.9E-18
Josephine Robertson 41361833 DNA methylation P36955 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0722028 6.7E-18
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0732178 1.1E-17
Josephine Robertson 41361833 DNA methylation Q99459 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.079 1.4E-17
Pfeiffer L 25583993 Triglycerides DNA methylation Whole blood Discovery 1776 cg19693031 chr1:145441552 TXNIP -0.03 1.9E-17
Josephine Robertson 41361833 DNA methylation A0A075B7B8 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.078 4E-17
Josephine Robertson 41361833 DNA methylation P00747 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0714813 5.6E-17
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0760092 6.6E-17
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.069 8.1E-17
Gomez-Alonso MDC 33413638 DNA methylation VLDL-D Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -0.11 8.5E-17
Josephine Robertson 41361833 DNA methylation P02750 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.07 9.5E-17
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.071 9.6E-17
Gomez-Alonso MDC 33413638 DNA methylation S-VLDL-CE_pct Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP 0.65 1.9E-16
Gomez-Alonso MDC 33413638 DNA methylation XS-VLDL-TG_pct Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -0.78 2E-16
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0761042 2.7E-16
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.067 4.8E-16
Albao D. 31691802 DNA methylation Type II diabetes mellitus Whole Blood Linear regression 365 cg19693031 chr1:145441552 TXNIP NA 5.8E-16
Soriano-Tarraga C 26643952 DNA methylation HbA1c Peripheral blood BASICMAR 1 268 cg19693031 chr1:145441552 TXNIP -0.129 7.3E-16
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery and replication adjusted for BMI 4261 cg19693031 chr1:145441552 TXNIP -0.0134 7.6E-16
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.069 9.4E-16
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.066 9.6E-16
Gomez-Alonso MDC 33413638 DNA methylation S-VLDL-C_pct Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP 0.45 1E-15
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.066 1.1E-15
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0742449 1.2E-15
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0659692 1.3E-15
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg22525212 chr1:145437802 TXNIP 0.00035 1.5E-15
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.065 2.4E-15
Josephine Robertson 41361833 DNA methylation P00742 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0673379 3.4E-15
Justice AE 32901515 waist circumference-to-hip ratio DNA methylation Whole blood discovery 2684 cg19693031 chr1:145441552 TXNIP -0.15 3.5E-15
Gomez-Alonso MDC 33413638 DNA methylation L-VLDL-L Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -3.9 5.2E-15
Gomez-Alonso MDC 33413638 DNA methylation L-VLDL-P Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -3.9 6E-15
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.064 6.8E-15
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery 2306 cg19693031 chr1:145441552 TXNIP -0.0174243 9.4E-15
Cardona A 31506343 Type II diabetes DNA methylation Whole blood Replication in Indians 2664 cg19693031 chr1:145441552 TXNIP -0.386 1.2E-14
Dugue P-A 31789449 Alcohol consumption DNA methylation Whole blood Lifetime consumption discovery 5606 cg19693031 chr1:145441552 TXNIP NA 1.3E-14
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.071 1.5E-14
Richard MA 29198723 DNA methylation Diastolic Blood Pressure Whole blood, CD4+ T cells Meta-analysis 17010 cg19693031 chr1:145441552 TXNIP -0.0003 1.8E-14
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.065 2.1E-14
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.063062 2.1E-14
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.063 2.3E-14
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.065 3E-14
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.065 3E-14
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.064 4.4E-14
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0637185 4.8E-14
Gomez-Alonso MDC 33413638 DNA methylation L-VLDL-FC Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -5.0 5.1E-14
Gomez-Alonso MDC 33413638 DNA methylation MUFAtoFA Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -0.32 6.5E-14
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0641217 6.5E-14
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.064 6.7E-14
Juvinao-Quintero DL 33622391 DNA methylation Type 2 diabetes Whole blood meta-analysis 3428 cg19693031 chr1:145441552 TXNIP -0.019 8.8E-14
Josephine Robertson 41361833 DNA methylation A0A0C4DH25 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.069 9.6E-14
Chambers JC 26095709 Type II diabetes DNA methylation Peripheral blood Discovery 2664 cg19693031 chr1:145441552 TXNIP -0.08338161 1E-13
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.061 1.2E-13
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.063 1.5E-13
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.063 1.6E-13
Gomez-Alonso MDC 33413638 DNA methylation L-VLDL-TG Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -4.3 2.3E-13
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg00497091 chr1:145438415 TXNIP 0.00033 2.6E-13
Gomez-Alonso MDC 33413638 DNA methylation L-VLDL-PL Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -4.1 2.6E-13
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.062 3.2E-13
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.062 4.7E-13
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0596016 5E-13
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg12769891 chr1:145438217 TXNIP 0.0061 6E-13
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.061 8.8E-13
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.061 1.1E-12
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.061 1.1E-12
Soriano-Tarraga C 26643952 DNA methylation Type II diabetes Peripheral blood BASICMAR 1 355 cg19693031 chr1:145441552 TXNIP -0.35 1.2E-12
Jiantao Ma 30796027 DNA methylation hepatic fat whole blood Discovery 1496 cg19693031 chr1:145441552 TXNIP NA 1.3E-12
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.058 1.4E-12
Gomez-Alonso MDC 33413638 DNA methylation S-LDL-TG_pct Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -0.76 1.5E-12
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Discovery adjusted for BMI 2306 cg19693031 chr1:145441552 TXNIP -0.0165139 1.7E-12
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.06 2E-12
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.06 2.3E-12
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.06 2.5E-12
Josephine Robertson 41361833 DNA methylation A0A0B4J1V0 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.058 2.7E-12
Gomez-Alonso MDC 33413638 DNA methylation IDL.TG_pct Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -0.72 2.9E-12
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.065 3E-12
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.057 3.3E-12
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.059 3.3E-12
Gomez-Alonso MDC 33413638 DNA methylation S-HDL-TG Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -0.8 4.1E-12
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.064 5.2E-12
Josephine Robertson 41361833 DNA methylation P01780 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.064 5.3E-12
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0564964 7.5E-12
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.056 8.5E-12
Gomez-Alonso MDC 33413638 DNA methylation L-VLDL-C Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -4.2 8.7E-12
Liu C 27843151 DNA methylation Alcohol consumption per day Whole blood European ancestry 9643 cg19693031 chr1:145441552 TXNIP -0.00043938 1E-11
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.063 1.1E-11
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg17745163 chr1:145438331 TXNIP 0.0068 1.2E-11
Josephine Robertson 41361833 DNA methylation A0A0G2JRQ6 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.058 1.4E-11
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.056 1.5E-11
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.056 1.5E-11
Justice AE 32901515 waist circumference-to-height DNA methylation Whole blood discovery 2684 cg19693031 chr1:145441552 TXNIP -0.084 1.7E-11
Josephine Robertson 41361833 DNA methylation O14791 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0574929 1.7E-11
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.055 1.8E-11
Ma J 30936141 DNA methylation Hepatic Fat Whole blood Meta-analysis model 1 3400 cg19693031 chr1:145441552 TXNIP NA 2E-11
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0621413 2.1E-11
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.055 2.3E-11
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0600193 2.8E-11
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg10713626 chr1:145438766 TXNIP 0.032 2.8E-11
Josephine Robertson 41361833 DNA methylation A0A0C4DH36 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.057 3.1E-11
Josephine Robertson 41361833 DNA methylation A0A0C4DH36 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.054 4.1E-11
Ma J 30936141 DNA methylation Hepatic Fat Whole blood Meta-analysis model 2 3400 cg19693031 chr1:145441552 TXNIP NA 4.3E-11
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.056 4.5E-11
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0559304 5.6E-11
Josephine Robertson 41361833 DNA methylation A0A0A0MT89 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.061 6.1E-11
Josephine Robertson 41361833 DNA methylation A0A0A0MS14 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.054 6.9E-11
Josephine Robertson 41361833 DNA methylation A0A0A0MS14 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.056 7.2E-11
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.054 7.6E-11
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg04280493 chr1:145438949 TXNIP 0.0077 7.9E-11
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.054 8.2E-11
Josephine Robertson 41361833 DNA methylation A0A087WSY6 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.06 8.4E-11
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0535179 8.8E-11
Josephine Robertson 41361833 DNA methylation A0A075B6H7 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.06 9.6E-11
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.055 9.9E-11
Marttila S 25888029 DNA methylation Age group Peripheral blood mononuclear cells - 143 cg19693031 chr1:145441552 TXNIP 0.68 1.1E-10
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0549869 1.2E-10
Gomez-Alonso MDC 33413638 DNA methylation VLDL-TG Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -1.9 1.2E-10
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.06 1.6E-10
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0534434 1.6E-10
Josephine Robertson 41361833 DNA methylation A0A0B4J1V0 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.055 1.6E-10
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.055 1.8E-10
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.054 1.8E-10
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.054 2E-10
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg04280493 chr1:145438949 TXNIP 0.0074 2.2E-10
Gomez-Alonso MDC 33413638 DNA methylation Serum-TG Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -1.5 2.3E-10
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0520159 2.9E-10
Josephine Robertson 41361833 DNA methylation A0A0C4DH36 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.054 3.4E-10
Josephine Robertson 41361833 DNA methylation P04114 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0523671 4.3E-10
Josephine Robertson 41361833 DNA methylation A0A0C4DH34 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.058 4.6E-10
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg22690212 chr1:145438435 TXNIP -0.01534 5.1E-10
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.057 5.1E-10
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.05718 5.1E-10
Josephine Robertson 41361833 DNA methylation A0A0J9YX35 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.057 6.3E-10
Josephine Robertson 41361833 DNA methylation A0A0B4J1V0 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.053 7E-10
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0527561 7.2E-10
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0526711 7.3E-10
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg12769891 chr1:145438217 TXNIP 0.00021 7.3E-10
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0524206 8.3E-10
Singmann P 26500701 DNA methylation Sex Whole blood KORA F4 1799 cg19693031 chr1:145441552 TXNIP NA 9.4E-10
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.052 1E-09
Josephine Robertson 41361833 DNA methylation A0A0A0MS14 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.052 1.2E-09
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.052 1.4E-09
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.05 1.5E-09
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.052 1.6E-09
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0497683 1.6E-09
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.052 1.7E-09
Josephine Robertson 41361833 DNA methylation P02671 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.051 1.8E-09
Josephine Robertson 41361833 DNA methylation A0A0A0MS15 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.049 2E-09
Gomez-Alonso MDC 33413638 DNA methylation UnSat Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP 0.12 2.2E-09
Gomez-Alonso MDC 33413638 DNA methylation M-VLDL-FC Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -1.9 2.4E-09
Josephine Robertson 41361833 DNA methylation P01602 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.051 2.4E-09
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0491836 2.5E-09
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0491416 2.6E-09
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.049 2.7E-09
Liu Y 23334450 DNA methylation Rheumatoid arthritis Whole blood - 691 cg13305883 chr1:145438423 TXNIP 0.0054 2.9E-09
Gomez-Alonso MDC 33413638 DNA methylation M-VLDL-TG Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -2.2 3.1E-09
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.049 3.3E-09
Josephine Robertson 41361833 DNA methylation A0A075B6J9 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.049 3.4E-09
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0504864 3.7E-09
Justice AE 32901515 waist circumference DNA methylation Whole blood discovery 2684 cg19693031 chr1:145441552 TXNIP -0.057 4.1E-09
Gomez-Alonso MDC 33413638 DNA methylation IDL.FC_pct Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP 0.16 4.9E-09
Soriano-Tarraga C 26643952 DNA methylation HbA1c Peripheral blood BASICMAR 2 162 cg19693031 chr1:145441552 TXNIP -0.144 5.1E-09
Gomez-Alonso MDC 33413638 DNA methylation PUFAtoFA Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP 0.29 5.4E-09
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.048 7.1E-09
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0476754 7.6E-09
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.048 7.7E-09
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg04280493 chr1:145438949 TXNIP 0.00042 7.9E-09
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.049 9E-09
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0490906 9.6E-09
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.049 9.6E-09
Imgenberg-Kreuz J 26857698 DNA methylation Primary Sjogrens syndrome Whole blood Whole blood 500 cg20064151 chr1:145438865 TXNIP NA 9.7E-09
Josephine Robertson 41361833 DNA methylation P01718 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.053 1.2E-08
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.051 1.2E-08
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0488656 1.2E-08
Gomez-Alonso MDC 33413638 DNA methylation Ile Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -0.54 1.3E-08
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.049 1.3E-08
Imgenberg-Kreuz J 26857698 DNA methylation Primary Sjogrens syndrome Whole blood Whole blood 500 cg22690212 chr1:145438435 TXNIP NA 1.5E-08
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood sensitivity 18225 cg19693031 chr1:145441552 TXNIP 0.15 1.8E-08
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.048 1.8E-08
Josephine Robertson 41361833 DNA methylation P08603 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.044284 1.9E-08
Gomez-Alonso MDC 33413638 DNA methylation XS-VLDL-TG Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -1.1 2.1E-08
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0478153 2.1E-08
Josephine Robertson 41361833 DNA methylation P01700 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.052 2.4E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg18879829 chr1:145438131 TXNIP 0.00053 2.5E-08
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19389852 chr1:145439013 TXNIP 0.027 2.6E-08
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0472761 2.6E-08
Josephine Robertson 41361833 DNA methylation A0A075B6J9 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.048 2.7E-08
Josephine Robertson 41361833 DNA methylation P02749 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0458569 2.7E-08
Josephine Robertson 41361833 DNA methylation A0A0A0MS15 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.047 3.1E-08
Nicolas Fragoso-Bargas 36534481 DNA methylation HOMA-IR Whole blood discovery 456 cg19693031 chr1:145441552 TXNIP -0.139283258 3.1E-08
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0514161 3.2E-08
Josephine Robertson 41361833 DNA methylation P05160 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0455307 3.4E-08
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0506762 3.6E-08
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0511212 3.7E-08
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.047 3.7E-08
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0469833 3.8E-08
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg25173010 chr1:145438031 TXNIP -0.00046 4E-08
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0468317 4.4E-08
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0463166 4.5E-08
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0464988 5.5E-08
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg19301058 chr1:145438404 TXNIP 0.045 6.3E-08
Gadd DA 35945220 SCUBE1 protein levels (SeqId = 8989-40) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.73 6.5E-08
Braun KVE 28194238 DNA methylation Triglycerides Whole blood Discovery and replication 1485 cg19693031 chr1:145441552 TXNIP -0.0133 6.7E-08
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.046 6.8E-08
Nicolas Fragoso-Bargas 36534481 DNA methylation HOMA-IR Whole blood discovery (european) 294 cg19693031 chr1:145441552 TXNIP -0.194252543 7.7E-08
Josephine Robertson 41361833 DNA methylation A0A0A0MS14 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.05 8.6E-08
Josephine Robertson 41361833 DNA methylation A0A0B4J1V0 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.05 9.6E-08
Gomez-Alonso MDC 33413638 DNA methylation TGtoPG Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -0.64 9.7E-08
Chung SA 26192630 DNA methylation Autoantibody production in systemic lupus erythematosus Peripheral blood Combined 326 cg19693031 chr1:145441552 TXNIP NA 1E-07
Josephine Robertson 41361833 DNA methylation A0A075B6J9 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.046 1E-07
Josephine Robertson 41361833 DNA methylation P02749 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0496178 1.1E-07
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0482878 1.1E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg22221669 chr1:145438279 TXNIP -0.00014 1.1E-07
Imgenberg-Kreuz J 26857698 DNA methylation Primary Sjogrens syndrome Whole blood Whole blood 500 cg19389852 chr1:145439013 TXNIP NA 1.1E-07
Mamtani M 26798409 Liability function of hypertriglyceridemic waist DNA methylation Peripheral blood - 850 cg19693031 chr1:145441552 TXNIP 0.3 1.2E-07
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0434659 1.4E-07
Josephine Robertson 41361833 DNA methylation A0A0A0MS15 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.045 1.5E-07
Josephine Robertson 41361833 DNA methylation A0A075B6J9 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.049 1.6E-07
Josephine Robertson 41361833 DNA methylation P18428 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0432489 1.6E-07
Ma J 30936141 Nonalcoholic fatty liver disease DNA methylation Whole Blood, Monocytes discovery and replication 4525 cg19693031 chr1:145441552 TXNIP NA 1.7E-07
Ma J 30936141 DNA methylation Hepatic Fat Whole blood Meta-analysis model 3 3400 cg19693031 chr1:145441552 TXNIP NA 1.7E-07
Josephine Robertson 41361833 DNA methylation P80108 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0444946 1.9E-07
Gadd DA 35945220 PRSS8 protein levels (SeqId = 15513-108) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.7 2.2E-07
Huang D 32520614 DNA methylation Systolic Blood Pressure Whole blood Discovery 4820 cg19693031 chr1:145441552 TXNIP NA 2.2E-07
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.044 2.2E-07
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0425891 2.5E-07
Josephine Robertson 41361833 DNA methylation Q13790 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.043 2.7E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg20064151 chr1:145438865 TXNIP -0.0014 2.9E-07
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg17175624 chr1:145438920 TXNIP 0.012 3E-07
Josephine Robertson 41361833 DNA methylation P04003 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0472383 3E-07
Ma J 32525743 DNA methylation Mediterranean diet Whole blood, CD4+ T-cells, CD14+ monocytes European meta-analysis 6662 cg19693031 chr1:145441552 TXNIP 0.003 3.1E-07
Josephine Robertson 41361833 DNA methylation P02749 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0437723 3.2E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg22525212 chr1:145437802 TXNIP 0.0011 3.2E-07
Liu J 31197173 DNA methylation fasting glucose whole blood Base plus BMI 4808 cg19693031 chr1:145441552 TXNIP -0.95 3.3E-07
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.042 3.4E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH29 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.042 3.4E-07
Josephine Robertson 41361833 DNA methylation P01743 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.042 3.8E-07
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0471583 4.3E-07
Florath I 26433941 DNA methylation Type II diabetes Whole blood Discovery adjusted for leucocyte composition 988 cg19693031 chr1:145441552 TXNIP -0.029 4.5E-07
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg19301058 chr1:145438404 TXNIP 0.0061 4.7E-07
Florath I 26433941 DNA methylation Type II diabetes Whole blood Replication 527 cg19693031 chr1:145441552 TXNIP -0.036 4.8E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.043 4.9E-07
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg22619763 chr1:145438623 TXNIP -0.01047 5.1E-07
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0468827 5.1E-07
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0425566 6.1E-07
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0410971 6.4E-07
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.041 6.5E-07
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.043 6.5E-07
Josephine Robertson 41361833 DNA methylation O75882 whole blood OSCA model 1 14671 cg17175624 chr1:145438920 TXNIP -0.041052 6.6E-07
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg17745163 chr1:145438331 TXNIP -6.5e-05 7.4E-07
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0456658 7.6E-07
Liu J 31197173 DNA methylation fasting glucose whole blood Base 4808 cg19693031 chr1:145441552 TXNIP -0.95 7.6E-07
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.044 7.7E-07
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Any maternal smoking in pregnancy effect on newborns 6685 cg19693031 chr1:145441552 TXNIP -0.006 8E-07
Josephine Robertson 41361833 DNA methylation P05160 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0460663 8E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH36 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.046 8.4E-07
Josephine Robertson 41361833 DNA methylation A0A0C4DH38 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.046 8.4E-07
Josephine Robertson 41361833 DNA methylation P01705 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.04 9.9E-07
Gadd DA 35945220 OXT protein levels (SeqId = 8356-88) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.66 1E-06
Josephine Robertson 41361833 DNA methylation P02749 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0418063 1.1E-06
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0401689 1.1E-06
Josephine Robertson 41361833 DNA methylation P06310 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.045 1.2E-06
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.041 1.3E-06
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0399573 1.3E-06
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0413907 1.3E-06
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Replication 1955 cg19693031 chr1:145441552 TXNIP -0.0109322 1.3E-06
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0413462 1.4E-06
Soriano-Tarraga C 26643952 DNA methylation Type II diabetes Peripheral blood BASICMAR 2 167 cg19693031 chr1:145441552 TXNIP -0.3 1.4E-06
Florath I 26433941 DNA methylation Type II diabetes Whole blood Discovery 988 cg19693031 chr1:145441552 TXNIP -0.03 1.5E-06
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.045 1.7E-06
Sayols-Baixeras S 28173150 Serum triglycerides DNA methylation Whole blood Discovery adjusted for surrogate variables 645 cg19693031 chr1:145441552 TXNIP -0.043 1.7E-06
Gadd DA 35945220 ALDOB protein levels (SeqId = 18185-118) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.64 1.8E-06
Josephine Robertson 41361833 DNA methylation P00740 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0403807 1.8E-06
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns 5647 cg19693031 chr1:145441552 TXNIP -0.008 1.9E-06
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.041 2E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 2 at 9y with age as a random effect 2338 cg18879829 chr1:145438131 TXNIP 0.0015 2.1E-06
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.039 2.2E-06
Gadd DA 35945220 ACY1 protein levels (SeqId = 3343-1) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.63 2.3E-06
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.04 2.6E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg19389852 chr1:145439013 TXNIP -0.0015 2.7E-06
Battram T 23334450 DNA methylation Rheumatoid arthritis Whole blood EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE42861 689 cg19693031 chr1:145441552 TXNIP 0.02 2.9E-06
Gadd DA 35945220 APOC3 protein levels (SeqId = 6461-54) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.63 3.2E-06
Josephine Robertson 41361833 DNA methylation P01709 whole blood OSCA model 1 14671 cg04280493 chr1:145438949 TXNIP 0.038 3.2E-06
Josephine Robertson 41361833 DNA methylation Q9Y5Y7 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.043 3.3E-06
Josephine Robertson 41361833 DNA methylation P14151 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.04 3.4E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0382843 3.5E-06
Josephine Robertson 41361833 DNA methylation P01743 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.04 3.6E-06
Gomez-Alonso MDC 33413638 DNA methylation M-VLDL-P Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -1.8 3.7E-06
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0394095 4E-06
Josephine Robertson 41361833 DNA methylation A0A075B6H9 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.043 4.1E-06
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 1 14671 cg19301058 chr1:145438404 TXNIP -0.0380066 4.1E-06
Gomez-Alonso MDC 33413638 DNA methylation M-VLDL-L Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -1.7 4.4E-06
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0392347 4.5E-06
Josephine Robertson 41361833 DNA methylation Q08380 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0389207 4.6E-06
Josephine Robertson 41361833 DNA methylation P01701 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.043 4.6E-06
Josephine Robertson 41361833 DNA methylation P01705 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.039 5E-06
Josephine Robertson 41361833 DNA methylation P02649 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0391864 5E-06
Gadd DA 35945220 PRSS2 protein levels (SeqId = 5034-79) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.61 5.2E-06
Gadd DA 35945220 PSAT1 protein levels (SeqId = 18342-2) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.61 5.4E-06
Gadd DA 35945220 GLTPD2 protein levels (SeqId = 7948-129) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.61 5.5E-06
Battram T None DNA methylation Total lipids in small HDL Whole blood None 685 cg19693031 chr1:145441552 TXNIP -1.29 5.6E-06
Josephine Robertson 41361833 DNA methylation P05160 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0387222 6E-06
Josephine Robertson 41361833 DNA methylation P01705 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.039 6.3E-06
Josephine Robertson 41361833 DNA methylation P04430 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.037 6.3E-06
Joubert BR 27040690 DNA methylation Maternal smoking in pregnancy Cord blood Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts 5647 cg19693031 chr1:145441552 TXNIP -0.006 7E-06
Sikdar S 31536415 DNA methylation Prenatal smoke exposure Cord blood, whole blood Inverse varience-weighted fixed-effects meta-analysis 5648 cg19693031 chr1:145441552 TXNIP -0.0058 7E-06
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.038 7.3E-06
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0370063 7.3E-06
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a random effect 2338 cg25173010 chr1:145438031 TXNIP 0.00052 8.2E-06
Josephine Robertson 41361833 DNA methylation A0A0A0MS15 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.042 8.3E-06
Josephine Robertson 41361833 DNA methylation P05160 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0381361 8.8E-06
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0378645 8.9E-06
Tobi EW None DNA methylation maternal glucose cord blood fasting glucose meta-EWAS 2404 cg19693031 chr1:145441552 TXNIP -0.0047 9.4E-06
Gadd DA 35945220 RBP5 protein levels (SeqId = 19241-31) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.59 1E-05
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.036 1E-05
Josephine Robertson 41361833 DNA methylation P05546 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0371982 1.1E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.039 1.1E-05
Josephine Robertson 41361833 DNA methylation P01743 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.038 1.2E-05
Gomez-Alonso MDC 33413638 DNA methylation FAw6toFA Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP 0.28 1.2E-05
Battram T None DNA methylation Concentration of small HDL particles Whole blood None 684 cg19693031 chr1:145441552 TXNIP NA 1.2E-05
Josephine Robertson 41361833 DNA methylation P01743 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.041 1.3E-05
Josephine Robertson 41361833 DNA methylation P20851 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0404074 1.3E-05
Gadd DA 35945220 CPM protein levels (SeqId = 9416-77) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.59 1.3E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.036 1.4E-05
Hedman AK 28213390 DNA methylation Serum triglycerides Whole blood Replication adjusted for BMI 1955 cg19693031 chr1:145441552 TXNIP -0.01027 1.5E-05
Gadd DA 35945220 PYY protein levels (SeqId = 3727-35) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.58 1.6E-05
Gadd DA 35945220 C9 protein levels (SeqId = 3060-43) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP 0.57 1.6E-05
Liu C 27843151 DNA methylation Alcohol consumption per day CD14+ monocytes CD14+ monocytes 1251 cg19693031 chr1:145441552 TXNIP -0.000496 1.7E-05
Josephine Robertson 41361833 DNA methylation P01619 whole blood OSCA model 1 14671 cg04280493 chr1:145438949 TXNIP 0.036 1.7E-05
Gadd DA 35945220 GPD1 protein levels (SeqId = 13697-51) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.58 1.8E-05
Gadd DA 35945220 CES1 protein levels (SeqId = 15487-164) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.57 1.8E-05
Josephine Robertson 41361833 DNA methylation P08185 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.036555 1.9E-05
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.037 1.9E-05
Gomez-Alonso MDC 33413638 DNA methylation M-VLDL-PL Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -1.6 1.9E-05
Florath I 26433941 DNA methylation Type II diabetes Whole blood Replication adjusted for leucocyte composition 527 cg19693031 chr1:145441552 TXNIP -0.031 1.9E-05
Josephine Robertson 41361833 DNA methylation P20742 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.037 1.9E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I0 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.035 2E-05
Gadd DA 35945220 KRT1 protein levels (SeqId = 9931-20) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.57 2E-05
Josephine Robertson 41361833 DNA methylation P35858 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0394328 2.1E-05
Josephine Robertson 41361833 DNA methylation P01023 whole blood OSCA model 4 14671 cg17175624 chr1:145438920 TXNIP -0.0469172 2.1E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I0 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.036 2.1E-05
Josephine Robertson 41361833 DNA methylation P78563 whole blood OSCA model 3 14671 cg19301058 chr1:145438404 TXNIP -0.0356508 2.1E-05
Josephine Robertson 41361833 DNA methylation P43251 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0362308 2.3E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg01728667 chr1:145439281 TXNIP -0.00036 2.4E-05
Battram T None DNA methylation Phospholipids in small HDL Whole blood None 684 cg19693031 chr1:145441552 TXNIP -1.93 2.4E-05
Chambers JC 26095709 Type II diabetes DNA methylation Peripheral blood Replication 1141 cg19693031 chr1:145441552 TXNIP -0.0408 2.5E-05
Battram T None DNA methylation Free cholesterol in small HDL Whole blood None 684 cg19693031 chr1:145441552 TXNIP -11.3 2.6E-05
Gomez-Alonso MDC 33413638 DNA methylation MUFA Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP -0.89 2.7E-05
Gadd DA 35945220 CELA2A protein levels (SeqId = 7140-1) DNA methylation Whole blood SomaScan protein measurement 774 cg01728667 chr1:145439281 TXNIP -0.72 2.8E-05
Josephine Robertson 41361833 DNA methylation P02743 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0349997 2.8E-05
Josephine Robertson 41361833 DNA methylation P01705 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.039 2.9E-05
Josephine Robertson 41361833 DNA methylation P02765 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0345026 2.9E-05
Josephine Robertson 41361833 DNA methylation P01766 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.036 3E-05
Josephine Robertson 41361833 DNA methylation B1AHL2 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.035 3.1E-05
Josephine Robertson 41361833 DNA methylation P02765 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP -0.0356236 3.2E-05
Josephine Robertson 41361833 DNA methylation P01706 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP 0.034 3.2E-05
Josephine Robertson 41361833 DNA methylation P07996 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0386187 3.3E-05
Singmann P 26500701 DNA methylation Sex Whole blood Meta-analysis 1999 cg19693031 chr1:145441552 TXNIP NA 3.3E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 4 14671 cg22619763 chr1:145438623 TXNIP 0.04 3.4E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.038 3.7E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.035 3.7E-05
Battram T 30602389 DNA methylation Tissue Buccal cells and peripheral blood mononuclear cells EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells 215 cg00497091 chr1:145438415 TXNIP 0.0055 3.8E-05
Gadd DA 35945220 HMGCS1 protein levels (SeqId = 13496-19) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.55 3.8E-05
Cronjé HT 31910897 DNA methylation Triglycerides Whole blood None 117 cg19693031 chr1:145441552 TXNIP -0.0477 3.9E-05
Gomez-Alonso MDC 33413638 DNA methylation L-LDL-FC_pct Whole blood Meta-analysis 5414 cg19693031 chr1:145441552 TXNIP 0.17 3.9E-05
Josephine Robertson 41361833 DNA methylation A0A0B4J1U7 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.035 4E-05
Josephine Robertson 41361833 DNA methylation P01714 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.038 4E-05
Robert F. Hillary doi.org/10.1101/2023.11.02.23298000 C-reactive protein (CRP) levels DNA methylation Whole blood Fully-adjusted model 14040 cg19693031 chr1:145441552 TXNIP -0.72 4.1E-05
Gadd DA 35945220 PCSK7 protein levels (SeqId = 4459-68) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.55 4.1E-05
Gadd DA 35945220 ALDH1A1 protein levels (SeqId = 11265-8) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.55 4.2E-05
Battram T 25282492 DNA methylation Age Fetal liver, adult liver EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE61278. Compared fetal liver tissue to adult liver tissue of different individuals 110 cg04280493 chr1:145438949 TXNIP 0.36 4.3E-05
Gadd DA 35945220 SHBG protein levels (SeqId = 4929-55) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP 0.55 4.3E-05
Josephine Robertson 41361833 DNA methylation P01344 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0380355 4.5E-05
Huang D 32520614 DNA methylation Diastolic Blood Pressure Whole blood Discovery 4820 cg19693031 chr1:145441552 TXNIP NA 4.6E-05
Gadd DA 35945220 MGAT4B protein levels (SeqId = 7141-21) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.545 4.8E-05
Hannah M. Smith 39706196 DNA methylation HDL cholesterol Whole blood discovery 18225 cg20064151 chr1:145438865 TXNIP 0.073 5E-05
Battram T None DNA methylation Leucine Whole blood None 684 cg19693031 chr1:145441552 TXNIP -16.0 5.2E-05
Josephine Robertson 41361833 DNA methylation P01344 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0333393 5.4E-05
Josephine Robertson 41361833 DNA methylation P02790 whole blood OSCA model 1 14671 cg00497091 chr1:145438415 TXNIP 0.033 5.5E-05
Battram T None DNA methylation Glucose Whole blood fasting 682 cg19693031 chr1:145441552 TXNIP -0.31 5.6E-05
Gadd DA 35945220 PTK7 protein levels (SeqId = 9525-1) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.54 5.7E-05
Josephine Robertson 41361833 DNA methylation O43866 whole blood OSCA model 2 14671 cg19693031 chr1:145441552 TXNIP 0.034 5.7E-05
Josephine Robertson 41361833 DNA methylation P02747 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.037 5.8E-05
Josephine Robertson 41361833 DNA methylation A0A075B6I0 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.034 5.9E-05
Gadd DA 35945220 ALDOC protein levels (SeqId = 9876-20) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.539 5.9E-05
Gadd DA 35945220 AKR1D1 protein levels (SeqId = 18398-1) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.54 6.4E-05
Josephine Robertson 41361833 DNA methylation P07360 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP -0.0341614 6.4E-05
Josephine Robertson 41361833 DNA methylation P00748 whole blood OSCA model 1 14671 cg19693031 chr1:145441552 TXNIP -0.0329089 6.7E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 2 14671 cg18879829 chr1:145438131 TXNIP 0.033 6.8E-05
Nuotio ML 33239708 DNA methylation Metabolic Sydnrome Whole blood Discovery 517 cg19693031 chr1:145441552 TXNIP -0.12444 7E-05
Gadd DA 35945220 DGKB protein levels (SeqId = 12895-28) DNA methylation Whole blood SomaScan protein measurement 774 cg13305883 chr1:145438423 TXNIP 0.8 7.5E-05
Josephine Robertson 41361833 DNA methylation P02765 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP -0.0368857 7.6E-05
Josephine Robertson 41361833 DNA methylation P02751 whole blood OSCA model 1 14671 cg17175624 chr1:145438920 TXNIP -0.0326351 7.7E-05
Gadd DA 35945220 ZNF23 protein levels (SeqId = 11565-58) DNA methylation Whole blood SomaScan protein measurement 774 cg13305883 chr1:145438423 TXNIP 0.8 7.7E-05
Hannah M. Smith 39706196 DNA methylation Body fat Whole blood discovery 17304 cg22690212 chr1:145438435 TXNIP -0.116512 7.7E-05
Josephine Robertson 41361833 DNA methylation P01009 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.037 7.9E-05
Mulder RH 33450751 DNA methylation age Whole blood Model 1 with age as a fixed effect 2338 cg18879829 chr1:145438131 TXNIP -0.00029 7.9E-05
Josephine Robertson 41361833 DNA methylation P06396 whole blood OSCA model 3 14671 cg19693031 chr1:145441552 TXNIP 0.034 7.9E-05
Josephine Robertson 41361833 DNA methylation P29622 whole blood OSCA model 3 14671 cg18879829 chr1:145438131 TXNIP 0.033 8E-05
Gadd DA 35945220 SERPINA3 protein levels (SeqId = 4153-11) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP 0.53 8.1E-05
Gadd DA 35945220 KLB protein levels (SeqId = 19557-3) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.527 8.1E-05
Josephine Robertson 41361833 DNA methylation P01703 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.037 8.3E-05
Josephine Robertson 41361833 DNA methylation P04430 whole blood OSCA model 4 14671 cg19693031 chr1:145441552 TXNIP 0.037 8.4E-05
Gadd DA 35945220 ADH1C protein levels (SeqId = 15525-294) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.53 8.4E-05
Neumann A 33184255 ADHD DNA methylation Cord Blood At birth 2477 cg01728667 chr1:145439281 TXNIP 3.4 9.5E-05
Gadd DA 35945220 AKR7A3 protein levels (SeqId = 18173-11) DNA methylation Whole blood SomaScan protein measurement 774 cg19693031 chr1:145441552 TXNIP -0.52 9.5E-05
Gadd DA 35945220 PNLIP protein levels (SeqId = 15613-16) DNA methylation Whole blood SomaScan protein measurement 774 cg01728667 chr1:145439281 TXNIP -0.67 9.7E-05
Gadd DA 35945220 TYMS protein levels (SeqId = 5035-7) DNA methylation Whole blood SomaScan protein measurement 774 cg00497091 chr1:145438415 TXNIP 0.9 9.8E-05

 

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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

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