author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg05575921	chr5:373378	5	373378	AHRR	North shore	-0.003	0.000161	9.73e-78	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg23576855	chr5:373299	5	373299	AHRR	North shore	-0.003	0.000197	3.73e-52	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg01940273	chr2:233284934	2	233284934	-	Island	-0.0013	8.9e-05	6.9e-48	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg21566642	chr2:233284661	2	233284661	-	Island	-0.002	0.000138	2.59e-47	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg26703534	chr5:377358	5	377358	AHRR	South shelf	-7e-04	5e-05	3.16e-45	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg03636183	chr19:17000585	19	17000585	F2RL3	North shore	-0.0016	0.000126	4.550000000000001e-37	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg21161138	chr5:399360	5	399360	AHRR	Open sea	-9e-04	7.5e-05	9.01e-33	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg14817490	chr5:392920	5	392920	AHRR	Open sea	-0.001	9.6e-05	2.87e-25	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg05951221	chr2:233284402	2	233284402	-	Island	-0.0011	0.000106	3.86e-25	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg11660018	chr11:86510915	11	86510915	PRSS23	North shore	-6e-04	6.2e-05	5.43e-22	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg05284742	chr14:93552128	14	93552128	ITPK1	Open sea	-4e-04	4.4e-05	4.62e-20	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg03329539	chr2:233283329	2	233283329	-	North shore	-5e-04	5.6e-05	4.44e-19	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg19859270	chr3:98251294	3	98251294	GPR15	Open sea	-3e-04	3.4e-05	1.72e-18	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg00310412	chr15:74724918	15	74724918	SEMA7A	North shore	-4e-04	4.7e-05	8.34e-18	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg06126421	chr6:30720080	6	30720080	-	Open sea	-0.0012	0.000142	2.85e-17	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg14580211	chr5:150161299	5	150161299	C5orf62	South shelf	-6e-04	7.2e-05	4.89e-17	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg09935388	chr1:92947588	1	92947588	GFI1	Island	-0.0012	0.00015	0.00000000000000151	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg23771366	chr11:86510998	11	86510998	PRSS23	North shore	-6e-04	7.6e-05	0.00000000000000277	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg15342087	chr6:30720209	6	30720209	-	Open sea	-4e-04	5.1e-05	0.00000000000000358	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg21611682	chr11:68138269	11	68138269	LRP5	Open sea	-4e-04	5.1e-05	0.00000000000000551	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg25648203	chr5:395444	5	395444	AHRR	Open sea	-6e-04	7.7e-05	0.00000000000000875	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg20295214	chr1:206226794	1	206226794	AVPR1B	South shelf	-4e-04	5.3e-05	0.0000000000000313	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg08709672	chr1:206224334	1	206224334	AVPR1B	South shore	-4e-04	5.3e-05	0.0000000000000496	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg25949550	chr7:145814306	7	145814306	CNTNAP2	South shore	-3e-04	4.4e-05	0.00000000000837	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg23916896	chr5:368804	5	368804	AHRR	North shore	-5e-04	7.4e-05	0.0000000000126	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg07339236	chr20:50312490	20	50312490	ATP9A	Open sea	-3e-04	4.6e-05	0.0000000000607	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg23161492	chr15:90357202	15	90357202	ANPEP	North shore	-6e-04	9.2e-05	0.0000000000814	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg25189904	chr1:68299493	1	68299493	GNG12	South shore	-9e-04	0.00015	0.00000000187	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg11554391	chr5:321320	5	321320	AHRR	Island	-3e-04	5e-05	0.00000000236	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg02451831	chr7:26578098	7	26578098	KIAA0087	Open sea	-4e-04	6.7e-05	0.000000003	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg02583484	chr12:54677008	12	54677008	HNRNPA1;HNRPA1L-2	South shelf	-3e-04	5.4e-05	0.0000000341	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg22132788	chr7:45002486	7	45002486	MYO1G	Island	5e-04	9.2e-05	0.0000000599	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg18316974	chr1:92947035	1	92947035	GFI1	Island	-3e-04	5.9e-05	0.000000375	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg18642234	chr3:49394622	3	49394622	GPX1	North shore	-3e-04	6e-05	0.000000516	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg05668853	chr17:27044169	17	27044169	RAB34	Island	-3e-04	6e-05	0.000000545	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg14316231	chr8:41895100	8	41895100	MYST3	Open sea	-2e-04	4.8e-05	0.0000307	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg21140898	chr1:51442318	1	51442318	-	North shore	-5e-04	0.000121	0.0000352	-	26826776_serum_cotinine_replication
Zhang Y	-	26826776	2016-04-01	Serum cotinine	EFO_0007813	Replication	Table 2	DNA methylation	Serum cotinine	Age, sex, body mass index, physical activity, total cholesterol, systolic blood pressure, prevalence of cardiovascular disease, diabetes, cancer, leukocyte, cell counts and technical covariates	Beta values	ng/ml	Illumina HumanMethylation450	Whole blood	-	500	1	62	Both	European	cg13751113	chr11:118085214	11	118085214	AMICA1	Open sea	-1e-04	2.5e-05	0.0000733	-	26826776_serum_cotinine_replication
