author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg25823837	chr12:129338783	12	129338783	GLT1D1	South shore	0.058203	0.011132	0.000000171	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg08754149	chr10:78204159	10	78204159	C10orf11	Open sea	-0.074561	0.01506	0.000000738	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg01748627	chr11:67272202	11	67272202	PITPNM1	Island	-0.050142	0.01013	0.000000742	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00897703	chr2:135434956	2	135434956	TMEM163	Open sea	-0.062944	0.012945	0.00000116	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg09444818	chr4:102097226	4	102097226	PPP3CA	Open sea	0.083033	0.017077	0.00000116	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg02691035	chr16:89163800	16	89163800	ACSF3	North shelf	-0.065571	0.013644	0.00000154	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg04136369	chr17:36070600	17	36070600	HNF1B	Open sea	0.0685	0.014336	0.00000177	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg06784691	chr1:2245988	1	2245988	-	Island	0.065592	0.013731	0.00000178	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg06289725	chr11:62689081	11	62689081	CHRM1	North shore	0.10095	0.021148	0.00000181	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18628732	chr6:30095295	6	30095295	-	Island	0.052782	0.011109	0.00000202	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg01649773	chr11:27015991	11	27015991	FIBIN	Open sea	0.056437	0.01197	0.00000242	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg01430588	chr17:56769767	17	56769767	TEX14;RAD51C	North shore	-0.060068	0.012789	0.00000264	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg11787160	chr12:113515332	12	113515332	DTX1	Island	0.100598	0.021578	0.00000313	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg01595951	chr5:54834655	5	54834655	-	South shelf	-0.10129	0.021745	0.00000319	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg26952936	chr16:23724854	16	23724854	ERN2	South shore	0.051565	0.011105	0.00000343	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg14981253	chr7:5112642	7	5112642	LOC389458	South shore	0.080715	0.017386	0.00000344	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg16639540	chr12:716805	12	716805	NINJ2	North shore	0.076675	0.01652	0.00000346	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg21816330	chr17:27044629	17	27044629	RAB34	Island	0.064455	0.013966	0.00000393	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg14757543	chr22:28010428	22	28010428	-	Island	0.051897	0.011245	0.00000393	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg24777028	chr5:141348256	5	141348256	RNF14	North shore	0.06595	0.014405	0.00000469	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg06777352	chr16:19124984	16	19124984	ITPRIPL2	North shore	0.058825	0.012853	0.00000472	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg19843457	chr12:132288611	12	132288611	-	South shelf	0.059674	0.013051	0.00000482	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13917578	chr5:143547850	5	143547850	YIPF5	North shelf	-0.050444	0.011068	0.00000517	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg21334513	chr6:30095248	6	30095248	-	Island	0.084904	0.018638	0.00000523	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg27282900	chr6:30095258	6	30095258	-	Island	0.058159	0.012789	0.00000543	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23744638	chr11:10323902	11	10323902	-	North shore	0.082554	0.018218	0.00000586	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg16659470	chr8:94744382	8	94744382	RBM12B	Open sea	0.053207	0.01175	0.00000595	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18892212	chr16:31499991	16	31499991	SLC5A2	Island	0.064503	0.014297	0.00000643	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13804575	chr9:109626999	9	109626999	ZNF462	South shelf	0.097383	0.021626	0.0000067	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg05260085	chr19:46003095	19	46003095	FLJ40125	South shore	0.058446	0.01299	0.00000682	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg27428708	chr16:54851977	16	54851977	-	Open sea	0.083238	0.01856	0.0000073	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg08250081	chr4:10125330	4	10125330	-	Open sea	0.075416	0.016819	0.00000733	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg02098413	chr6:105308735	6	105308735	HACE1	South shore	-0.052681	0.011759	0.00000746	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg25291978	chr6:144386422	6	144386422	PLAGL1	South shore	-0.052171	0.011696	0.00000818	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00566516	chr7:128784097	7	128784097	TSPAN33	North shore	0.053593	0.01205	0.00000869	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg26337070	chr2:85999873	2	85999873	ATOH8	Open sea	0.099347	0.022389	0.00000911	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg04383058	chr11:67273507	11	67273507	PITPNM1	North shore	-0.053871	0.012169	0.00000956	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18064171	chr12:47219956	12	47219956	SLC38A4	Open sea	0.052766	0.011938	0.00000987	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg20702913	chr2:10183115	2	10183115	KLF11	Island	0.055452	0.012551	0.00000995	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17055704	chr6:33282879	6	33282879	ZBTB22;TAPBP	Island	0.062753	0.014207	0.00001	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17264240	chr4:186456976	4	186456976	PDLIM3	South shore	0.078552	0.017792	0.0000101	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18633154	chr14:77296234	14	77296234	C14orf166B	Open sea	-0.05728	0.012993	0.0000104	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17118478	chr2:191543902	2	191543902	NAB1	Open sea	-0.054503	0.01244	0.0000118	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg03517083	chr16:75569527	16	75569527	CHST5	Open sea	0.07117	0.016244	0.0000118	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23475018	chr3:124277638	3	124277638	KALRN	Open sea	-0.059783	0.013679	0.0000124	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg24980653	chr4:1399235	4	1399235	-	Island	0.05423	0.012413	0.0000125	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg15406387	chr4:111397332	4	111397332	ENPEP	North shore	0.06292	0.014442	0.0000132	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg19645639	chr1:113500384	1	113500384	SLC16A1	South shore	-0.070889	0.016283	0.0000134	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg12940993	chr14:21271148	14	21271148	RNASE1	Open sea	0.055786	0.012829	0.0000137	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg22429121	chr1:27901805	1	27901805	AHDC1	Island	0.072855	0.016772	0.000014	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg02979520	chr3:48471575	3	48471575	PLXNB1	South shore	0.052996	0.012209	0.0000142	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18872749	chr17:42421993	17	42421993	GRN	Open sea	0.057053	0.013176	0.0000149	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13461273	chr3:40547232	3	40547232	ZNF620	North shore	0.05948	0.013746	0.0000151	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13474083	chr9:136362373	9	136362373	-	Open sea	0.055738	0.012881	0.0000151	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg22738642	chr12:43137977	12	43137977	-	Open sea	-0.08491	0.019629	0.0000152	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg01919208	chr3:49170496	3	49170496	LAMB2	Open sea	0.064235	0.014869	0.0000156	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg16550264	chr12:115813214	12	115813214	-	Open sea	-0.08321	0.019268	0.0000157	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23506143	chr5:55761274	5	55761274	-	Open sea	0.106915	0.024835	0.0000167	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg21491107	chr16:85649026	16	85649026	KIAA0182	Island	0.068471	0.015915	0.0000169	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00852921	chr20:62120544	20	62120544	EEF1A2	Island	0.06996	0.016261	0.0000169	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg24837370	chr2:5833774	2	5833774	SOX11	Island	0.082113	0.01918	0.0000186	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg01480384	chr12:54020711	12	54020711	ATF7	South shore	-0.06553	0.015311	0.0000187	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg02276944	chr2:157291826	2	157291826	GPD2	North shore	0.053666	0.01255	0.000019	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg08248579	chr6:17988937	6	17988937	KIF13A	South shore	0.070027	0.016453	0.0000208	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg01015662	chr1:40598394	1	40598394	-	North shore	0.076595	0.018058	0.0000222	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg04204452	chr17:1479213	17	1479213	SLC43A2	Island	0.052564	0.012396	0.0000223	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13035046	chr3:13115843	3	13115843	IQSEC1	South shore	0.054436	0.01284	0.0000224	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg04543516	chr20:21589093	20	21589093	-	Open sea	0.062139	0.014661	0.0000225	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg25879142	chr7:4671391	7	4671391	-	Open sea	0.056752	0.013411	0.0000232	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17322044	chr12:125140105	12	125140105	-	Open sea	0.095406	0.022561	0.0000235	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg04622802	chr11:27015872	11	27015872	FIBIN	Open sea	0.059471	0.01407	0.0000237	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg07584855	chr1:221055545	1	221055545	HLX	Island	0.063368	0.015079	0.0000264	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00174992	chr2:169659121	2	169659121	NOSTRIN	Open sea	0.062876	0.014983	0.0000271	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23079252	chr6:30095199	6	30095199	-	Island	0.076347	0.018221	0.0000279	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg07980854	chr20:57586338	20	57586338	-	South shelf	0.055141	0.01316	0.0000279	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg25109396	chr14:91317056	14	91317056	-	Open sea	0.084174	0.020113	0.0000285	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17161520	chr11:67174843	11	67174843	TBC1D10C	North shelf	-0.062641	0.014973	0.0000287	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg04173396	chr8:61821400	8	61821400	-	North shore	0.065947	0.015772	0.000029	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00557630	chr19:51017123	19	51017123	ASPDH	North shelf	0.050478	0.012084	0.0000295	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg21789008	chr8:118764818	8	118764818	-	Open sea	-0.050638	0.012125	0.0000296	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg25972578	chr10:92548822	10	92548822	HTR7	Open sea	-0.078487	0.018796	0.0000297	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg06202737	chr2:128166279	2	128166279	-	South shore	0.062276	0.014933	0.0000304	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg14485097	chr7:4671479	7	4671479	-	Open sea	0.060212	0.014438	0.0000304	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg12092579	chr1:178380975	1	178380975	RASAL2	Open sea	-0.061823	0.014827	0.0000305	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg01872024	chr11:94502804	11	94502804	AMOTL1	South shore	0.064854	0.015576	0.0000313	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg12812233	chr4:40752838	4	40752838	NSUN7	Island	0.075538	0.018154	0.0000317	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg26413942	chr5:124081751	5	124081751	ZNF608	Open sea	0.070067	0.016842	0.0000318	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg16399833	chr14:104345945	14	104345945	-	Open sea	0.057033	0.013719	0.0000322	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg11161961	chr3:152554430	3	152554430	P2RY1	South shore	0.061088	0.014697	0.0000323	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg04002235	chr11:128560443	11	128560443	-	Island	0.078085	0.018786	0.0000323	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg14016177	chr9:131965610	9	131965610	-	Island	0.060796	0.014631	0.0000325	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13098139	chr6:33422938	6	33422938	ZBTB9	South shore	0.087907	0.02116	0.0000326	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00958927	chr1:175162553	1	175162553	KIAA0040	South shore	0.060934	0.014679	0.0000331	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18273840	chr5:45695643	5	45695643	HCN1	Island	0.058353	0.014069	0.0000336	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg26081900	chr5:180429512	5	180429512	BTNL3	Open sea	0.053922	0.013011	0.0000341	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg11700959	chr12:7066664	12	7066664	PTPN6	Open sea	-0.053054	0.012832	0.0000356	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18081863	chr19:50015527	19	50015527	FCGRT	North shore	0.069801	0.016883	0.0000356	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg19645616	chr19:10444917	19	10444917	RAVER1;ICAM3	Island	0.092395	0.022362	0.000036	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg06287775	chr7:4784174	7	4784174	FOXK1	North shore	0.1073	0.025978	0.0000362	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg08196561	chr16:87525539	16	87525539	ZCCHC14	Open sea	0.068348	0.016555	0.0000365	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23336702	chr8:134585815	8	134585815	-	South shore	-0.054959	0.013316	0.0000367	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23786205	chr10:77057425	10	77057425	-	South shelf	-0.064654	0.015667	0.0000368	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg26675654	chr7:1269693	7	1269693	-	Island	0.055858	0.01354	0.000037	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg16407699	chr10:74020428	10	74020428	-	North shore	-0.051751	0.012554	0.0000375	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18252102	chr13:98796790	13	98796790	FARP1	South shore	0.089871	0.021826	0.0000383	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23333072	chr17:37856228	17	37856228	ERBB2	North shore	0.052423	0.012734	0.0000384	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17009297	chr5:158526642	5	158526642	EBF1	North shore	-0.073929	0.017986	0.0000395	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg03280622	chr8:145023013	8	145023013	PLEC1	North shore	0.056665	0.013788	0.0000396	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg26290219	chr6:33128906	6	33128906	-	North shore	0.063476	0.015447	0.0000397	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23716690	chr1:10314029	1	10314029	KIF1B	Open sea	0.097971	0.023845	0.0000398	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg12656497	chr21:43099292	21	43099292	NCRNA00111	Open sea	0.063155	0.015399	0.0000411	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg11262216	chr17:41723227	17	41723227	MEOX1	Island	0.063808	0.015573	0.0000418	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg12656653	chr10:13771427	10	13771427	FRMD4A	Open sea	0.053886	0.013157	0.0000421	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg14972155	chr5:54281198	5	54281198	ESM1	Open sea	0.086371	0.021097	0.0000424	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg09907936	chr19:58570466	19	58570466	ZNF135	Island	0.052248	0.012776	0.0000432	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13503148	chr3:171561060	3	171561060	TMEM212	Open sea	0.085712	0.020975	0.0000438	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18538340	chr3:132756780	3	132756780	TMEM108	North shore	0.056707	0.01388	0.000044	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg05924254	chr4:1107720	4	1107720	RNF212	Island	0.067847	0.016643	0.0000457	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18104919	chr5:7851396	5	7851396	C5orf49	Island	0.056402	0.013839	0.0000459	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18906360	chr14:60633047	14	60633047	DHRS7	South shore	-0.059815	0.01468	0.0000461	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg22820108	chr12:125003218	12	125003218	NCOR2	Island	0.052641	0.012929	0.0000467	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg15371881	chr5:142065819	5	142065819	FGF1	Open sea	0.061799	0.015187	0.0000472	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13466988	chr1:12538541	1	12538541	VPS13D	Open sea	0.075193	0.01851	0.0000486	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg07110405	chr11:70917533	11	70917533	SHANK2	Open sea	0.131054	0.032261	0.0000486	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg02657865	chr6:32077744	6	32077744	TNXB	Open sea	0.074106	0.018253	0.0000491	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg22160463	chr17:47755834	17	47755834	SPOP	South shore	0.055546	0.013686	0.0000494	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17485681	chr10:73565625	10	73565625	CDH23	Island	0.06307	0.015542	0.0000495	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg08469215	chr1:156261351	1	156261351	TMEM79	Island	0.067468	0.01663	0.0000497	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg25390787	chr6:49681299	6	49681299	CRISP2	Open sea	0.088447	0.021821	0.0000505	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg04812509	chr10:90342738	10	90342738	RNLS	Island	-0.052519	0.012959	0.0000506	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg05994850	chr6:30095341	6	30095341	-	Island	0.053486	0.013203	0.000051	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00460983	chr10:91133941	10	91133941	-	Open sea	0.088311	0.021807	0.0000513	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg06536868	chr2:27530884	2	27530884	UCN	Island	0.070533	0.017439	0.0000524	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg14847009	chr1:175162515	1	175162515	KIAA0040	South shore	0.055244	0.013662	0.0000526	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg07226201	chr22:27834629	22	27834629	-	Island	0.071272	0.017639	0.0000533	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg09978105	chr14:103227646	14	103227646	-	Open sea	0.052103	0.012896	0.0000534	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg05745631	chr6:30095178	6	30095178	-	Island	0.078572	0.019454	0.0000537	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg26758396	chr20:6104274	20	6104274	FERMT1	South shore	0.063743	0.015786	0.0000539	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg20167366	chr6:30094980	6	30094980	-	North shore	0.055047	0.013638	0.0000543	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13148544	chr20:30196119	20	30196119	-	Island	0.079853	0.019784	0.0000543	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg10533331	chr15:38857695	15	38857695	RASGRP1	South shore	0.063949	0.015854	0.0000549	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg02571819	chr12:124017613	12	124017613	RILPL1	Island	0.078159	0.019391	0.0000556	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23436584	chr12:98833359	12	98833359	-	Open sea	0.05402	0.013419	0.0000568	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg22571135	chr7:55377050	7	55377050	-	Open sea	-0.068953	0.017133	0.0000571	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13725590	chr2:96809174	2	96809174	DUSP2	North shore	-0.060968	0.015169	0.0000584	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg02009395	chr16:20702744	16	20702744	ACSM1	Open sea	-0.062191	0.015477	0.0000586	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg14557202	chr12:54764371	12	54764371	ZNF385A	Island	0.074749	0.018617	0.0000594	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13080282	chr12:24717178	12	24717178	-	South shore	0.063403	0.015808	0.0000605	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg19954000	chr5:142065671	5	142065671	FGF1	Open sea	0.062182	0.015509	0.0000609	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg05667311	chr10:98797490	10	98797490	SLIT1	Open sea	0.050913	0.012701	0.0000611	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg09334514	chr1:236686671	1	236686671	LGALS8	North shore	0.073734	0.018398	0.0000613	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00859858	chr1:37944257	1	37944257	ZC3H12A	South shelf	-0.084349	0.021055	0.0000617	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18322510	chr1:236686618	1	236686618	LGALS8	North shore	0.092419	0.023106	0.0000634	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg15379633	chr22:23487586	22	23487586	RAB36	Island	0.068934	0.017234	0.0000634	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg24642169	chr1:212731669	1	212731669	-	Island	0.054885	0.013736	0.0000645	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg19028499	chr7:3096493	7	3096493	-	Open sea	0.063487	0.01589	0.0000646	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg14896463	chr7:116592956	7	116592956	ST7OT4;ST7OT1;ST7	North shore	0.051984	0.013039	0.000067	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg20483374	chr11:119211646	11	119211646	C1QTNF5;MFRP	Island	0.067577	0.016957	0.0000674	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg21357291	chr18:55471021	18	55471021	-	Island	0.051191	0.01285	0.0000678	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg05059480	chr15:40633202	15	40633202	C15orf52	Open sea	0.063137	0.015851	0.000068	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg12186816	chr8:88160820	8	88160820	CNBD1	Open sea	-0.05735	0.014401	0.0000682	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg01123783	chr7:147591551	7	147591551	MIR548F3;CNTNAP2	Open sea	0.082286	0.020671	0.0000687	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00363845	chr19:17446137	19	17446137	ANO8	South shore	0.071178	0.017882	0.0000688	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg20451680	chr5:54281336	5	54281336	ESM1	Open sea	0.062427	0.015699	0.0000699	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg20592017	chr15:40364740	15	40364740	-	Open sea	0.071785	0.018061	0.0000705	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg19235339	chr10:90342899	10	90342899	RNLS	Island	-0.0529	0.013335	0.0000728	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg22169990	chr7:150786051	7	150786051	AGAP3	South shore	0.091388	0.023039	0.0000729	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg03906075	chr7:22894898	7	22894898	SNORD93	South shore	-0.056369	0.014219	0.0000736	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg03171770	chr10:43393728	10	43393728	-	Island	0.053628	0.013533	0.0000741	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg02133624	chr3:195590041	3	195590041	-	Open sea	0.063734	0.016105	0.0000758	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17675492	chr11:62679111	11	62679111	CHRM1	Open sea	-0.068116	0.017222	0.0000765	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg08034070	chr17:40805868	17	40805868	-	Island	0.05466	0.013829	0.0000773	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg09293816	chr19:50015532	19	50015532	FCGRT	North shore	0.064982	0.016441	0.0000774	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg10531073	chr22:38485757	22	38485757	BAIAP2L2	South shore	0.056189	0.014217	0.0000774	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg09117448	chr16:31439393	16	31439393	COX6A2	Island	0.078381	0.019841	0.000078	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg04124626	chr5:41509934	5	41509934	PLCXD3	Island	0.056295	0.014266	0.0000794	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg21156263	chr9:19926448	9	19926448	-	Open sea	0.09013	0.022872	0.0000813	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00262344	chr18:23713741	18	23713741	PSMA8	Island	0.06491	0.016485	0.0000823	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg14972814	chr11:95582409	11	95582409	MTMR2	Open sea	0.081137	0.02061	0.0000826	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg10407598	chr17:73629365	17	73629365	RECQL5;LOC643008	South shore	0.083664	0.021258	0.000083	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg12110437	chr8:144098888	8	144098888	LY6E;LOC100133669	North shore	-0.090757	0.023071	0.0000836	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg09659400	chr20:43744673	20	43744673	WFDC5	Open sea	-0.065522	0.01666	0.0000839	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg26372517	chr1:36039159	1	36039159	TFAP2E	Island	0.063462	0.016143	0.0000845	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23730027	chr3:57995180	3	57995180	FLNB	Island	0.057177	0.01455	0.0000851	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg21158528	chr1:211501629	1	211501629	TRAF5	South shore	-0.066476	0.016919	0.0000853	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17881353	chr17:44928210	17	44928210	WNT9B	North shore	0.050358	0.012818	0.0000854	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg08446539	chr12:25541565	12	25541565	-	South shelf	-0.055767	0.014196	0.0000855	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg06010588	chr8:35092876	8	35092876	UNC5D	Island	0.073473	0.01872	0.0000868	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg09591519	chr6:33241770	6	33241770	RPS18	South shore	-0.065823	0.01678	0.0000876	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23462514	chr4:1107585	4	1107585	RNF212	Island	0.074216	0.018923	0.0000878	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg12972064	chr3:171887393	3	171887393	FNDC3B	Open sea	0.083752	0.021356	0.0000879	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg23543481	chr14:23623684	14	23623684	SLC7A8	Open sea	0.052245	0.013322	0.0000879	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00498305	chr10:119000236	10	119000236	SLC18A2	North shore	0.051972	0.013263	0.0000891	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg09462576	chr1:228297873	1	228297873	MRPL55	South shore	0.057555	0.014691	0.0000894	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg20885179	chr3:38035831	3	38035831	VILL	Island	-0.052532	0.013411	0.0000896	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg24306340	chr1:64937451	1	64937451	CACHD1	South shore	0.063049	0.016099	0.0000899	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg14377922	chr2:23840537	2	23840537	KLHL29	Open sea	0.068711	0.017573	0.0000923	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg26738987	chr11:94135029	11	94135029	GPR83	South shore	0.053417	0.013666	0.0000928	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00123104	chr1:9884732	1	9884732	CLSTN1	South shore	0.070885	0.018136	0.0000929	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg19459332	chr15:98196247	15	98196247	-	Island	0.075657	0.019365	0.0000935	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg00207352	chr3:48470181	3	48470181	PLXNB1	North shore	0.052237	0.013374	0.0000939	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg11775521	chr11:74178795	11	74178795	KCNE3	Island	0.063527	0.016268	0.0000942	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg22700848	chr12:124990942	12	124990942	NCOR2	Open sea	0.056394	0.014445	0.0000946	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg18331412	chr5:135364986	5	135364986	TGFBI	Island	0.074165	0.019003	0.0000951	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg19710451	chr17:46654202	17	46654202	HOXB4	Island	0.054386	0.013937	0.0000953	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg15089806	chr1:43418199	1	43418199	SLC2A1	Open sea	-0.053108	0.013611	0.0000954	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg13700506	chr20:29892486	20	29892486	DEFB116	Open sea	0.057605	0.014764	0.0000955	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg06578434	chr19:1155225	19	1155225	SBNO2	Island	0.066162	0.01697	0.0000967	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg07058998	chr18:52625365	18	52625365	CCDC68	North shore	0.095454	0.02449	0.0000971	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg21402921	chr15:27112305	15	27112305	GABRA5	Island	0.052039	0.013352	0.0000972	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg03676485	chr7:2563816	7	2563816	LFNG	Island	0.059502	0.015271	0.0000976	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg12573871	chr18:72509555	18	72509555	ZNF407	Open sea	-0.074119	0.019023	0.0000977	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg24134292	chr8:142315841	8	142315841	-	North shelf	0.061101	0.015688	0.0000983	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg10321146	chr19:6822469	19	6822469	VAV1	Island	0.074209	0.019054	0.0000983	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg20217702	chr3:134094099	3	134094099	AMOTL2	South shore	0.052711	0.013537	0.0000987	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg06886374	chr16:1844152	16	1844152	IGFALS	South shore	0.055287	0.014202	0.0000991	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17061862	chr11:9590431	11	9590431	-	North shelf	0.058821	0.015111	0.0000992	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg01420564	chr2:179076804	2	179076804	OSBPL6	Open sea	-0.052534	0.013498	0.0000994	-	27564456_chronic_obstructive_pulmonary_disease
Morrow JD	-	27564456	2016-08-26	Chronic obstructive pulmonary disease	EFO_0000341	-	Table S2	DNA methylation	Chronic obstructive pulmonary disease	Age, sex, smoking pack-years, ethnicity and technical covariates	Beta values	-	Illumina HumanMethylation450	Lung	-	160	1	63.9	Both	European,African,Other	cg17845761	chr1:175162550	1	175162550	KIAA0040	South shore	0.063593	0.016344	0.0000999	-	27564456_chronic_obstructive_pulmonary_disease