author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg04983687	chr16:88558223	16	88558223	ZFPM1	Island	-4.7	0.3522	1.3e-40	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg09249800	chr1:6341287	1	6341287	ACOT7	Island	-6	0.4502	1.6e-40	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg11699125	chr1:6341327	1	6341327	ACOT7	Island	-5.3	0.4189	1.1e-36	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg12227660	chr10:135061670	10	135061670	MIR202	Open sea	-6.3	0.5082	2.7e-35	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg25087851	chr11:60623918	11	60623918	GPR44	South shelf	-6.3	0.5082	2.7e-35	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01000631	chr14:100610667	14	100610667	-	Island	-5.5	0.4477	1.1e-34	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08940169	chr16:88540241	16	88540241	ZFPM1	Island	-6.7	0.546	1.3e-34	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg15700636	chr11:57156050	11	57156050	PRG2	Open sea	-6.8	0.5557	2.0000000000000003e-34	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg21220721	chr1:6341230	1	6341230	ACOT7	Island	-4.1	0.3358	2.7e-34	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg10142874	chr2:11917623	2	11917623	LPIN1	Open sea	-6.5	0.5442	6.9e-33	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg04290133	chr7:65439512	7	65439512	GUSB	Open sea	-6.7	0.561	7.100000000000001e-33	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg12077754	chr2:75089669	2	75089669	HK2	Open sea	-5.3	0.4469	1.9e-32	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-6.2	0.5258	4.3000000000000004e-32	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26547058	chr8:142243143	8	142243143	-	Open sea	-6.8	0.5771	4.8e-32	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06528816	chr2:47242277	2	47242277	TTC7A	Open sea	-5.8	0.4941	8.200000000000001e-32	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg07970948	chr7:149543165	7	149543165	ZNF862	Open sea	-5	0.4274	1.3e-31	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg24491618	chr7:150649807	7	150649807	KCNH2	Island	-6.4	0.5471	1.3e-31	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg18550847	chr14:100610570	14	100610570	EVL	Island	-5.4	0.4632	2.1e-31	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg16263722	chr1:29523841	1	29523841	MECR	Open sea	-6.6	0.5669	2.4999999999999998e-31	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08776942	chr16:11729131	16	11729131	-	Open sea	-7.1	0.612	4.1e-31	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg16409452	chr14:100610186	14	100610186	EVL	North shore	-6.2	0.5436	3.9e-30	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01998785	chr16:55542709	16	55542709	LPCAT2	North shore	-6.2	0.5442	4.5000000000000004e-30	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg02985445	chr7:97908505	7	97908505	-	North shore	-6.4	0.5621	4.9000000000000004e-30	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg23706836	chr8:6407997	8	6407997	ANGPT2;MCPH1	Open sea	-5.1	0.4483	5.5000000000000005e-30	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg20885063	chr17:17939419	17	17939419	ATPAF2	North shelf	-6.2	0.5483	1.2e-29	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg16362140	chr5:10708717	5	10708717	DAP	Open sea	-5.9	0.5224	1.3999999999999998e-29	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg13645296	chr15:64275810	15	64275810	DAPK2	Open sea	-5.9	0.5279	5.3e-29	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg18666454	chr7:150651937	7	150651937	KCNH2	North shore	-6	0.5376	6.3e-29	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg04497992	chr16:616212	16	616212	NHLRC4	South shore	-6.1	0.5477	8.2e-29	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg13576859	chr9:97403129	9	97403129	FBP1	South shore	-6.2	0.5574	9.7e-29	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg21045547	chr20:35422703	20	35422703	C20orf117	Island	-7.8	0.7037	1.5000000000000002e-28	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg07562835	chr17:73734756	17	73734756	ITGB4	North shelf	-7.1	0.6434	2.6000000000000004e-28	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg23147443	chr7:150649655	7	150649655	KCNH2	Island	-5.2	0.4714	2.7000000000000003e-28	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg17988187	chr2:74612222	2	74612222	LOC100189589	Open sea	-6.1	0.5539	3.3e-28	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08889930	chr3:127317798	3	127317798	MCM2	South shore	-7.4	0.6746	5.400000000000001e-28	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06070625	chr3:69812798	3	69812798	MITF	Open sea	-6.2	0.5665	7e-28	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg18650626	chr7:1914073	7	1914073	MAD1L1	Island	-4.3	0.3933	7.900000000000001e-28	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg11456013	chr6:111192760	6	111192760	-	North shelf	-6.3	0.5772	9.700000000000002e-28	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg00944309	chr5:60142446	5	60142446	-	South shelf	-6.1	0.5594	1.1000000000000001e-27	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg20840540	chr6:42363749	6	42363749	TRERF1	Open sea	-8.2	0.752	1.1000000000000001e-27	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26787239	chr5:132008525	5	132008525	IL4	Open sea	-9.4	0.8633	1.3e-27	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg25939647	chr15:40173065	15	40173065	GPR176	Open sea	-5.2	0.4795	2.1e-27	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01445399	chr1:87596934	1	87596934	LOC339524	North shore	-6.9	0.6396	3.9000000000000004e-27	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg00114012	chr9:130158144	9	130158144	SLC2A8	North shore	-5.8	0.5381	4.3e-27	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg20673965	chr19:44220148	19	44220148	IRGC	North shelf	-6.5	0.6055	7e-27	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06391412	chr3:71295684	3	71295684	FOXP1	Open sea	-6.6	0.616	8.800000000000001e-27	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg03131767	chr12:123446272	12	123446272	ABCB9	South shore	-6.7	0.6261	9.999999999999999e-27	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg12819873	chr11:57157632	11	57157632	PRG2	Open sea	-7	0.6546	1.1e-26	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg14978242	chr5:79501131	5	79501131	SERINC5	Open sea	-5.9	0.5544	1.9e-26	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg07781995	chr1:87655840	1	87655840	-	Open sea	-7.5	0.7059	2.3e-26	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg21067750	chr15:40641778	15	40641778	PHGR1	Open sea	-7.8	0.7367	3.4e-26	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08773180	chr11:57157607	11	57157607	PRG2	Open sea	-5.6	0.5292	3.6e-26	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg04420917	chr19:39303993	19	39303993	LGALS4	Open sea	-7.1	0.6731	5.2e-26	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg21627181	chr6:25754190	6	25754190	SLC17A4	Open sea	-7.3	0.6973	1.2e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg25173129	chr17:56269410	17	56269410	EPX	Open sea	-6.6	0.6304	1.2e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg14613878	chr20:35504198	20	35504198	C20orf118	Open sea	-4.8	0.4591	1.4e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg21919729	chr8:11719367	8	11719367	CTSB	Open sea	-5.5	0.5273	1.8e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg07177867	chr15:52030746	15	52030746	LYSMD2	South shore	-7.1	0.6814	1.9999999999999998e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg00170714	chr17:40724562	17	40724562	MLX;PSMC3IP	Open sea	-6.6	0.6334	1.9999999999999998e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg02427831	chr19:51961937	19	51961937	SIGLEC8	Open sea	-7	0.6779	5.399999999999999e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg20836212	chr7:65419185	7	65419185	VKORC1L1	Open sea	-4.6	0.4459	5.9e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg22919538	chr3:48334413	3	48334413	-	Open sea	-8	0.7758	6.2e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg25224369	chr3:12918528	3	12918528	-	South shore	-6	0.582	6.399999999999999e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg10159529	chr3:3152530	3	3152530	IL5RA	Open sea	-6.2	0.6017	6.699999999999999e-25	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg07908654	chr13:41631052	13	41631052	-	North shelf	-5.9	0.5747	1.0000000000000001e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg13628444	chr9:134883788	9	134883788	MED27	Open sea	-6.5	0.6337	1.0999999999999998e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01649647	chr20:35177530	20	35177530	MYL9	Open sea	-6.9	0.6747	1.4999999999999998e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg17540765	chr17:73631586	17	73631586	RECQL5;LOC643008	South shelf	-6.4	0.6265	1.7e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06906869	chr13:52734154	13	52734154	NEK3	South shore	-7.2	0.7066	2.1999999999999996e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26235490	chr17:1047567	17	1047567	ABR	Open sea	-7.2	0.7066	2.1999999999999996e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg25488567	chr6:116781307	6	116781307	FAM26F	North shore	-7	0.6875	2.4e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg13562011	chr9:140308660	9	140308660	EXD3	North shelf	-6.6	0.6485	2.5e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01310029	chr3:3152374	3	3152374	IL5RA	Open sea	-6.9	0.6821	4.7e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26865494	chr10:129172573	10	129172573	DOCK1	Open sea	-7.8	0.7731	6.199999999999999e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01330991	chr17:7648108	17	7648108	DNAH2	South shelf	-5.6	0.5557	7.000000000000001e-24	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg13312337	chr2:74612759	2	74612759	LOC100189589	Open sea	-7	0.6999	1.5e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg15146567	chr3:42948626	3	42948626	ZNF662	South shore	-4.7	0.4699	1.5e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg25643253	chr7:65419190	7	65419190	VKORC1L1	Open sea	-5	0.4999	1.5e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg12555233	chr15:91455366	15	91455366	MAN2A2	Open sea	-8.1	0.8122	2.0000000000000002e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg02359181	chr19:34860339	19	34860339	GPI	South shelf	-7.2	0.7219	2.0000000000000002e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg14226212	chr9:113530240	9	113530240	MUSK	Open sea	-6.7	0.6745	3e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg16177693	chr1:27240669	1	27240669	NR0B2	Open sea	-5.4	0.544	3.2000000000000003e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg10298741	chr16:73019173	16	73019173	ZFHX3	Open sea	-6.5	0.656	3.8e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg04321303	chr7:44107504	7	44107504	-	South shelf	-5.3	0.5354	4.2e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg04217850	chr3:66428294	3	66428294	SLC25A26	Open sea	-8.2	0.8289	4.5000000000000003e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg17521120	chr19:51961666	19	51961666	SIGLEC8	Open sea	-5.7	0.5792	7.5e-23	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg11987455	chr1:43290834	1	43290834	ERMAP	Open sea	-7	0.7134	1e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06009042	chr5:150480839	5	150480839	ANXA6	Open sea	-6.4	0.6523	1e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg12614529	chr4:154269418	4	154269418	MND1	South shelf	-4.4	0.4506	1.6000000000000002e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg12172163	chr13:113825954	13	113825954	PROZ	Open sea	-5.8	0.597	2.6e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg19434937	chr12:7104184	12	7104184	LPCAT3	Open sea	-4.2	0.433	3e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg03492094	chr9:91994786	9	91994786	SEMA4D	North shore	-5.7	0.5891	3.8e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg09636525	chr4:7052612	4	7052612	TADA2B	Island	-7.8	0.8073	4.4e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06866208	chr16:67560245	16	67560245	-	North shelf	-6.2	0.6417	4.4e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg05219423	chr10:11291279	10	11291279	CUGBP2	Open sea	-5.8	0.6008	4.7e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg11385906	chr8:28745680	8	28745680	INTS9	North shelf	-6.2	0.6437	5.9e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26791242	chr1:87596895	1	87596895	LOC339524	North shore	-5.1	0.5296	6e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg03060158	chr3:48755856	3	48755856	IP6K2	South shore	-7.8	0.8103	6.2e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg16046667	chr20:35422698	20	35422698	C20orf117	Island	-4.8	0.4992	6.9e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg07819010	chr11:46619375	11	46619375	-	South shelf	-4.6	0.4802	9.7e-22	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg23943829	chr5:132009111	5	132009111	IL4	Open sea	-8.5	0.8932	1.8e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg11396585	chr6:33273477	6	33273477	TAPBP	Open sea	-7.8	0.8206	2e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg27469152	chr17:56282313	17	56282313	EPX	Open sea	-4.9	0.5158	2.1e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26953137	chr17:45573695	17	45573695	-	South shelf	-6.7	0.706	2.3e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg14025883	chr9:5436224	9	5436224	C9orf46	North shore	-6.1	0.6431	2.4e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg09535526	chr16:88558065	16	88558065	ZFPM1	Island	-4.9	0.5165	2.4e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26457013	chr19:55740188	19	55740188	TMEM86B	Open sea	-6.3	0.6662	3.2e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg00414077	chr20:35504511	20	35504511	C20orf118	Open sea	-5.1	0.5393	3.2e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg05465955	chr17:40715236	17	40715236	COASY	Island	-4.4	0.4655	3.3e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06154903	chr11:64642558	11	64642558	EHD1	North shelf	-3.9	0.4137	4.2e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg20290167	chr17:81040724	17	81040724	METRNL	North shore	-5.5	0.584	4.6e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg18972349	chr1:28195327	1	28195327	-	North shelf	-5.9	0.627	5e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06647928	chr5:73612203	5	73612203	-	Open sea	-5.1	0.5428	5.7e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg10387956	chr15:72646210	15	72646210	HEXA	Open sea	-6.6	0.7029	6e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg21239317	chr7:23640510	7	23640510	CCDC126	South shelf	-6.5	0.6926	6.3e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08808720	chr2:149639914	2	149639914	KIF5C;MIR1978	Open sea	-7.3	0.7784	6.7e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg20151107	chr10:126331425	10	126331425	FAM53B	Open sea	-7.3	0.7785	6.8e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg02473287	chr2:9752386	2	9752386	YWHAQ	Open sea	-5.9	0.6295	7.1e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26774971	chr6:158994407	6	158994407	TMEM181	Open sea	-6.2	0.6623	7.9e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg24202817	chr10:6220943	10	6220943	PFKFB3	Open sea	-7	0.7485	8.6e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg20263853	chr1:8824177	1	8824177	RERE	Open sea	-5.7	0.6105	9.9e-21	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg00582671	chr1:872235	1	872235	SAMD11	South shore	-4.5	0.483	1.2e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg18944099	chr6:31629199	6	31629199	C6orf47	South shore	-6.1	0.6547	1.2e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg16107105	chr7:150646704	7	150646704	KCNH2	North shore	-7.4	0.7943	1.2e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg02170785	chr14:69650830	14	69650830	-	Open sea	-6.4	0.6876	1.3e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg18783781	chr1:9599067	1	9599067	SLC25A33	North shore	-6.2	0.6672	1.5e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg25368824	chr5:132009352	5	132009352	IL4	Open sea	-6.2	0.669	1.9e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg23642826	chr1:6645463	1	6645463	ZBTB48	Open sea	-6.1	0.659	2.1e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg05720226	chr7:116786597	7	116786597	ST7;ST7OT2	Open sea	-6.4	0.6917	2.2e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26789365	chr10:133743048	10	133743048	-	Open sea	-6.7	0.7262	2.8e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg00844155	chr12:6576111	12	6576111	VAMP1	North shelf	-6.9	0.7485	3e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg09565310	chr5:112541553	5	112541553	MCC	Open sea	-6.1	0.6619	3.1e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06315149	chr1:2036398	1	2036398	PRKCZ	North shelf	-5.2	0.5654	3.7e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg14769121	chr7:98722470	7	98722470	SMURF1	Open sea	-4.8	0.5224	4e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg16905199	chr1:149676378	1	149676378	-	South shelf	-6.7	0.7296	4.2e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg22312249	chr17:72779428	17	72779428	TMEM104	Open sea	-5.2	0.5663	4.2e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg21498475	chr12:113737469	12	113737469	SLC24A6	Open sea	-4.6	0.5011	4.3e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg25135457	chr17:40715244	17	40715244	COASY	Island	-7	0.7629	4.5e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg00869582	chr16:12564745	16	12564745	SNX29	Open sea	-6.6	0.7205	5.2e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg12279125	chr8:2129970	8	2129970	-	Island	-4.4	0.4805	5.3e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg02826233	chr12:56365894	12	56365894	CDK2	North shore	-8.3	0.9065	5.4e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06756385	chr14:100610488	14	100610488	EVL	Island	-4.6	0.5027	5.7e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26873132	chr11:9191490	11	9191490	DENND5A	Open sea	-8.1	0.8858	6e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg19851574	chr6:167178233	6	167178233	RPS6KA2	Open sea	-2.9	0.3172	6.1e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg16599817	chr1:2036283	1	2036283	PRKCZ	North shelf	-4.1	0.4485	6.2e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg05958985	chr16:88558237	16	88558237	ZFPM1	Island	-5.4	0.5911	6.5e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08268892	chr6:157131429	6	157131429	ARID1B	Open sea	-5.9	0.6466	7.2e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg03519593	chr17:56274597	17	56274597	EPX	Island	-7.1	0.7792	8.1e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg02930951	chr20:48806066	20	48806066	CEBPB	North shore	-6.2	0.6805	8.2e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg04033850	chr12:49695016	12	49695016	-	South shelf	-7.7	0.8457	8.6e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg02475695	chr16:616220	16	616220	NHLRC4	South shore	-4.6	0.5058	9.5e-20	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg12077460	chr8:8702053	8	8702053	MFHAS1	Open sea	-4.6	0.5061	1e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg13221796	chr13:48876919	13	48876919	RB1	North shore	-4.9	0.5403	1.2e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08462941	chr19:5288631	19	5288631	PTPRS	North shore	-5.2	0.5734	1.2e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg23090159	chr7:65419194	7	65419194	VKORC1L1	Open sea	-4.7	0.5187	1.3e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg14355482	chr21:22373039	21	22373039	NCAM2	South shelf	-5.5	0.6081	1.5e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg18891604	chr6:36319055	6	36319055	-	Open sea	-6.9	0.764	1.7e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01916918	chr8:27461199	8	27461199	CLU	Open sea	-7.6	0.8415	1.7e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08404225	chr3:3151899	3	3151899	IL5RA	Open sea	-5.1	0.5651	1.8e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08969102	chr5:133563532	5	133563532	-	South shore	-4	0.4432	1.8e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg17041511	chr17:61509620	17	61509620	-	North shelf	-5.8	0.6427	1.8e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg21640749	chr17:72709731	17	72709731	RAB37;CD300LF	Open sea	-6.2	0.687	1.8e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg20317437	chr1:24172120	1	24172120	FUCA1	Open sea	-6.7	0.7433	2e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08886063	chr17:600398	17	600398	VPS53	Open sea	-7.1	0.7882	2.1e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg04305653	chr22:47272422	22	47272422	TBC1D22A	Open sea	-5.3	0.589	2.3e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01464484	chr11:67089352	11	67089352	LOC100130987	South shelf	-9.7	1.082	3.1e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg20328327	chr7:65419288	7	65419288	VKORC1L1	Open sea	-5.3	0.5919	3.4e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg13951007	chr1:146503900	1	146503900	LOC728989	Open sea	-6.3	0.7045	3.8e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg24343524	chr1:203763352	1	203763352	ZC3H11A	North shore	-7.1	0.797	5.2e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg27000590	chr8:8182003	8	8182003	PRAGMIN	Open sea	-5.8	0.6521	5.9e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg05499338	chr16:81517665	16	81517665	CMIP	Open sea	-6.8	0.7646	5.9e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg00068153	chr1:201028602	1	201028602	CACNA1S	Open sea	-6.7	0.7547	6.8e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg12425700	chr4:75186779	4	75186779	-	Open sea	-4.6	0.5181	6.8e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg18042632	chr21:42520902	21	42520902	C21orf130	Open sea	-5.9	0.6646	6.8e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg21104363	chr7:65419248	7	65419248	VKORC1L1	Open sea	-4.3	0.4844	6.9e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg15482717	chr11:70053254	11	70053254	FADD	South shelf	-5.6	0.6312	7.2e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg19328051	chr18:12380944	18	12380944	-	South shelf	-7.7	0.8684	7.5e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg13774539	chr2:74612706	2	74612706	LOC100189589	Open sea	-5	0.564	7.6e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg18805734	chr12:31453901	12	31453901	FAM60A	Open sea	-5.2	0.5879	9.1e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg13209388	chr1:6355060	1	6355060	ACOT7	Open sea	-3.4	0.3845	9.4e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg24058805	chr1:66777579	1	66777579	PDE4B	Open sea	-7.4	0.8374	9.8e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg04986931	chr22:39850128	22	39850128	-	North shelf	-5.5	0.6224	9.9e-19	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06725287	chr17:80533762	17	80533762	FOXK2	Island	-7	0.7923	1e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg10704177	chr1:62209607	1	62209607	INADL	South shore	-3.6	0.4088	1.3e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg02245534	chr17:81043668	17	81043668	METRNL	North shore	-5	0.5678	1.3e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg00986350	chr16:88540396	16	88540396	ZFPM1	Island	-4.8	0.5456	1.4e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01764046	chr1:32082577	1	32082577	HCRTR1	North shore	-7.7	0.876	1.5e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg07552087	chr16:2258457	16	2258457	MLST8	South shelf	-4.7	0.5347	1.5e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg02765496	chr9:71393662	9	71393662	FAM122A;PIP5K1B	North shore	-6	0.6851	2e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06597413	chr11:69251883	11	69251883	-	Open sea	-4.9	0.5595	2e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg13458609	chr9:130608923	9	130608923	ENG	Open sea	-4	0.457	2.1e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08165794	chr15:40568143	15	40568143	PAK6	North shelf	-6.8	0.7779	2.3e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg15817440	chr14:58599910	14	58599910	C14orf37	Open sea	-6.6	0.7554	2.4e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg08435683	chr20:4836338	20	4836338	SLC23A2	Open sea	-3.2	0.3663	2.4e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg15456821	chr11:61717225	11	61717225	BEST1	Open sea	-5.6	0.642	2.7e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg22503106	chr17:81040906	17	81040906	METRNL	North shore	-4.7	0.5402	3.3e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg03606098	chr1:1690840	1	1690840	NADK	North shore	-4.3	0.4944	3.4e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg16628205	chr7:100240094	7	100240094	TFR2	Open sea	-7.9	0.9093	3.7e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg06495615	chr19:939731	19	939731	ARID3A	Island	-5.5	0.6351	4.7e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg11668148	chr15:72636405	15	72636405	HEXA	Open sea	-6.5	0.7507	4.8e-18	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg09447105	chr12:15126020	12	15126020	PDE6H	Open sea	-6.2	0.7397	5.2e-17	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg11398517	chr20:42355625	20	42355625	GTSF1L	Open sea	-4.9	0.5922	1.3e-16	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg03693099	chr9:135936901	9	135936901	CEL	Open sea	-3.9	0.4767	2.8e-16	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg26136776	chr19:12998426	19	12998426	KLF1	South shore	-6.3	0.7796	6.4e-16	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg16050349	chr3:138478129	3	138478129	PIK3CB	Open sea	-5.8	0.7255	0.0000000000000013	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg05215575	chr16:4838722	16	4838722	SEPT12;LOC440335	Open sea	-5	0.6415	0.0000000000000065	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg15357945	chr11:57158361	11	57158361	PRG2	Open sea	-4.6	0.599	0.000000000000016	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg21631409	chr11:67449882	11	67449882	ALDH3B2	Open sea	-6.4	0.8653	0.00000000000014	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg25494227	chr12:10331614	12	10331614	C12orf59	Open sea	-4.5	0.7046	0.00000000017	-	28069425_total_serum_ige_discovery
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg09676390	chr21:46493345	21	46493345	ADARB1;C21orf122	North shore	-2.3	0.4122	0.000000024	-	28069425_total_serum_ige_discovery