author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg27657459	chr17:54853771	17	54853771	-	North shelf	-1.72	0.29	0.0000000084	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg01433914	chr10:111792543	10	111792543	ADD3	Open sea	-2.85	0.5	0.000000024	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg18569070	chr19:17136562	19	17136562	CPAMD8	Open sea	-2.69	0.48	0.000000045	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg26203572	chr7:47797675	7	47797675	-	Open sea	-3.94	0.7	0.000000048	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg04474209	chr15:52484920	15	52484920	MYO5C;GNB5	Open sea	-1.6	0.3	0.00000013	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg26771998	chr10:75490334	10	75490334	BMS1P4	Island	2.95	0.55	0.00000016	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg22727572	chr2:63272334	2	63272334	LOC100132215;EHBP1	Island	-5.87	1.1	0.0000002	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg07031542	chr1:214567074	1	214567074	PTPN14	Open sea	-2.2	0.42	0.00000026	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg06193393	chr7:99869454	7	99869454	GATS	Island	2.61	0.5	0.00000029	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg04104820	chr3:52291169	3	52291169	WDR82	Open sea	3.44	0.66	0.00000032	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg08866608	chr13:58203798	13	58203798	-	Island	2.69	0.52	0.00000032	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg23522780	chrX:118712792	X	118712792	UBE2A	South shelf	-1.92	0.37	0.00000036	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg25768273	chr1:211911579	1	211911579	-	Open sea	-1.41	0.28	0.00000074	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg12927915	chr8:66542625	8	66542625	ARMC1	North shelf	-1.56	0.31	0.00000074	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg14569423	chr9:126523663	9	126523663	DENND1A	Open sea	-1.42	0.28	0.00000082	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg26526443	chr6:27141658	6	27141658	-	North shelf	-1.53	0.3	0.00000086	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg16954236	chr18:8638786	18	8638786	RAB12	Open sea	-1.6	0.32	0.00000086	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg02539984	chr15:58960059	15	58960059	ADAM10	Open sea	-3.3	0.66	0.0000011	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg02679291	chr19:48248902	19	48248902	GLTSCR2	Island	4.73	0.95	0.0000011	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg13402936	chr15:50471108	15	50471108	-	North shelf	-2.29	0.46	0.0000012	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg12968518	chr2:148602504	2	148602504	ACVR2A	Island	2.01	0.41	0.0000014	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg25783997	chr2:185462928	2	185462928	ZNF804A	North shore	-2	0.41	0.0000015	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg23535170	chr3:179489892	3	179489892	USP13	Open sea	-1.41	0.29	0.0000015	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg02083528	chr1:78280850	1	78280850	FAM73A	South shelf	-1.8	0.37	0.0000017	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg13155823	chr8:80993721	8	80993721	TPD52	Open sea	-1.71	0.35	0.0000017	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg03976754	chr1:33330006	1	33330006	FNDC5	Open sea	-2.69	0.56	0.0000026	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg23260111	chr10:46158095	10	46158095	ANUBL1	Open sea	-1.29	0.27	0.0000026	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg22152887	chr11:72849944	11	72849944	FCHSD2	North shelf	-2.4	0.5	0.0000026	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg21246531	chr9:36039639	9	36039639	RECK	South shelf	-1.71	0.36	0.0000029	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg00008800	chr2:38710171	2	38710171	-	Open sea	-2.65	0.56	0.000003	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg08320413	chr10:127455161	10	127455161	MMP21	Open sea	-1.83	0.39	0.000003	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg00162673	chr1:51700514	1	51700514	RNF11	North shore	-2.25	0.48	0.0000033	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg11750112	chr1:64938742	1	64938742	CACHD1	South shelf	-2.57	0.54	0.0000033	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg04258046	chr15:63445591	15	63445591	RPS27L	North shelf	-1.56	0.33	0.000004	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg06632759	chr19:37702089	19	37702089	ZNF585B	Open sea	-2.59	0.55	0.000004	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg05180258	chr14:73921198	14	73921198	NUMB	North shelf	-1.52	0.33	0.0000059	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg06079966	chr6:26237621	6	26237621	-	North shelf	-2.42	0.53	0.0000068	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg11630696	chr3:79817333	3	79817333	ROBO1	South shore	2.4	0.53	0.0000078	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg21921829	chr7:116850153	7	116850153	ST7	Open sea	-1.32	0.29	0.0000086	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg08172999	chr2:200775722	2	200775722	C2orf69	North shore	1.94	0.43	0.0000094	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg17477493	chr8:12748272	8	12748272	-	Open sea	-2.03	0.45	0.000011	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg06501333	chr4:103419193	4	103419193	-	North shelf	-2.24	0.5	0.000012	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg07439409	chr6:97731296	6	97731296	MIR548H3;C6orf167	South shore	2.29	0.52	0.000012	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	ch.7.2714749F	chr7:130688396	7	130688396	FLJ43663	Open sea	2.37	0.53	0.000012	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg20667822	chr11:48153832	11	48153832	PTPRJ	Open sea	-1.44	0.32	0.000012	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg16743903	chr16:89593216	16	89593216	SPG7	Island	-2.11	0.47	0.000012	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg01885839	chr5:111017556	5	111017556	-	Open sea	-3.17	0.72	0.000014	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg09628499	chr17:56299729	17	56299729	-	South shelf	-1.57	0.36	0.000014	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg05999729	chr2:98369433	2	98369433	-	Open sea	-1.44	0.33	0.000016	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg23562675	chr2:120107745	2	120107745	C2orf76	Open sea	-1.43	0.33	0.000016	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg02456218	chr5:180476573	5	180476573	BTNL9	North shelf	-2.37	0.54	0.000016	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg05099186	chr13:39923838	13	39923838	LHFP	Open sea	2.22	0.51	0.000016	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg18462916	chr13:113918539	13	113918539	CUL4A	South shore	-1.74	0.4	0.000016	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg18726036	chr6:35543610	6	35543610	FKBP5	Open sea	-3.63	0.83	0.000017	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg06698332	chr1:151967449	1	151967449	S100A10	South shore	-1.93	0.44	0.000019	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg17345859	chr7:6728525	7	6728525	ZNF12	Open sea	-2.07	0.48	0.00002	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg13979573	chr14:21584590	14	21584590	-	Open sea	-1.45	0.34	0.00002	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg23253460	chr1:84709527	1	84709527	-	Open sea	-2.01	0.47	0.000021	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg01075555	chr13:63264349	13	63264349	-	Open sea	-2.42	0.56	0.000022	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg09664975	chr1:84543551	1	84543551	PRKACB	Island	-2.07	0.48	0.000023	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg22731164	chr15:40192158	15	40192158	GPR176	Open sea	-2.19	0.51	0.000023	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	ch.5.2738996F	chr5:145864698	5	145864698	TCERG1	Open sea	2.02	0.47	0.000024	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg02704946	chr17:6527184	17	6527184	KIAA0753	Open sea	-2.26	0.53	0.000024	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg19385799	chr3:78164711	3	78164711	-	Open sea	-1.8	0.42	0.000025	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg26569634	chr2:10760591	2	10760591	NOL10	Open sea	-1.37	0.32	0.000027	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg19977964	chr5:56206213	5	56206213	C5orf35	Island	2.36	0.56	0.000028	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg24495177	chr7:64362326	7	64362326	ZNF273	Open sea	-2.78	0.66	0.000029	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg25282652	chr12:128364739	12	128364739	-	Open sea	-1.79	0.42	0.00003	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg01021224	chr5:35049428	5	35049428	AGXT2	Open sea	-1.21	0.29	0.000032	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg01296653	chr9:4678949	9	4678949	CDC37L1	North shore	2.09	0.5	0.000032	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg03754165	chr2:60780427	2	60780427	BCL11A	North shore	1.96	0.47	0.000033	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg04872851	chr3:127007606	3	127007606	-	Open sea	-2.27	0.54	0.000035	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg10723575	chr3:149422266	3	149422266	WWTR1	Open sea	-2.44	0.59	0.00004	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg21331107	chr3:32541698	3	32541698	CMTM6	North shelf	-2.21	0.53	0.00004	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg21074594	chr11:43665775	11	43665775	-	Open sea	2.25	0.54	0.00004	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg09921682	chr7:50133131	7	50133131	ZPBP	South shore	-4.44	1.07	0.000041	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg13425650	chr12:94093761	12	94093761	CRADD	Open sea	-1.52	0.37	0.000041	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg23819836	chr6:15663134	6	15663134	DTNBP1	Island	2.22	0.54	0.000047	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg19780570	chr5:133764548	5	133764548	-	Open sea	-1.74	0.42	0.000051	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg13544125	chr11:14661502	11	14661502	PSMA1	North shelf	2.32	0.57	0.000056	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg04256065	chr17:76102509	17	76102509	TNRC6C	South shore	-3.45	0.85	0.000058	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg16719077	chr10:7849111	10	7849111	ATP5C1	Open sea	-1.52	0.38	0.000063	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg24310785	chr6:163985223	6	163985223	QKI	Open sea	-2.4	0.6	0.000069	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg15328990	chr8:92001646	8	92001646	-	South shelf	-1.03	0.26	0.000069	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg05099288	chr6:109700555	6	109700555	CD164	North shelf	1.87	0.47	0.000072	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	ch.11.2136200F	chr11:103819223	11	103819223	PDGFD	Open sea	2.47	0.62	0.000075	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg12361352	chr18:31158540	18	31158540	ASXL3	Open sea	-1.63	0.41	0.000075	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg25710815	chr4:89300116	4	89300116	HERC6	Island	3.61	0.9	0.000082	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg25269643	chr7:151042396	7	151042396	NUB1	South shelf	-2.06	0.52	0.000082	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication
Xu Z	EPIC-Italy	30989176	2019-04-15	breast cancer	EFO_0000305	Case vs Control Replication	Supplementary Table 1	DNA methylation	breast cancer	cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	329	1	Adults	Females	European	cg24152718	chr6:30185818	6	30185818	-	South shelf	-2.05	0.52	0.000088	None	30989176_Xu-Z_breast_cancer_case_vs_control_replication