author consortium pmid date trait efo analysis source outcome exposure covariates outcome_units exposure_units methylation_array tissue further_details n n_cohorts age sex ethnicity cpg chrpos chr pos gene type beta se p details study_id Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg03045325 chr11:63871265 11 63871265 MACROD1;FLRT1 Open sea -0.266 0.0000049 0.00000035 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg19854704 chr10:133508755 10 133508755 - South shore 0.165 0.000003 0.00000036 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg07728793 chr2:238771724 2 238771724 RAMP1 South shelf -0.155 0.0000029 0.00000049 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg18072629 chr10:8092036 10 8092036 - Island -0.112 0.0000021 0.0000007 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg05005073 chr1:39513326 1 39513326 - Open sea 0.233 0.0000044 0.0000008 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg09516627 chr2:25016290 2 25016290 CENPO;C2orf79 Island 0.155 0.000003 0.00000081 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg02727104 chr13:36729247 13 36729247 - Island 0.569 0.000011 0.00000087 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg26725813 chr15:35276608 15 35276608 ZNF770 North shelf -0.136 0.0000026 0.000001 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg05931551 chr1:52892210 1 52892210 ZCCHC11 Open sea -0.29 0.0000056 0.0000011 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg04512603 chr7:64345267 7 64345267 - Open sea -0.072 0.0000014 0.0000012 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg26392737 chr8:21916853 8 21916853 EPB49 South shelf 0.268 0.0000052 0.0000012 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg23218354 chr1:2885244 1 2885244 - Island 0.565 0.000011 0.0000014 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg09855212 chr11:85427572 11 85427572 SYTL2 Open sea 0.169 0.0000033 0.0000014 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg04305601 chr16:49699992 16 49699992 ZNF423 Open sea -0.215 0.0000042 0.0000017 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg01807862 chr5:54521833 5 54521833 - North shore -0.159 0.0000032 0.0000019 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg13590166 chr10:28749464 10 28749464 - Open sea -0.211 0.0000042 0.0000019 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg14781041 chr1:232649623 1 232649623 SIPA1L2 Open sea 0.105 0.0000021 0.0000023 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg03466415 chr2:167168852 2 167168852 SCN9A Open sea 0.142 0.0000028 0.0000023 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg15915658 chr11:65262358 11 65262358 - North shelf 0.307 0.0000061 0.0000023 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg22453818 chr5:77898627 5 77898627 LHFPL2 Open sea 0.254 0.0000051 0.0000024 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg18971416 chr10:25305175 10 25305175 THNSL1;ENKUR North shore 0.129 0.0000026 0.0000027 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg07175848 chr16:69327197 16 69327197 SNTB2 Open sea -0.204 0.0000041 0.0000027 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg18152712 chr6:20401723 6 20401723 E2F3 North shore 0.115 0.0000023 0.0000028 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg08060902 chr19:12595941 19 12595941 ZNF709 South shore -0.151 0.0000031 0.0000028 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg04963607 chr7:598459 7 598459 PRKAR1B North shore -0.135 0.0000027 0.0000029 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg00483825 chr10:134751640 10 134751640 C10orf93 Open sea -0.157 0.0000032 0.000003 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg18417562 chr5:138211909 5 138211909 CTNNA1;LRRTM2 Open sea -0.198 0.000004 0.0000031 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg09361653 chr17:78936292 17 78936292 RPTOR North shore -0.192 0.0000039 0.0000032 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg22896429 chr6:151261297 6 151261297 MTHFD1L Open sea 0.165 0.0000034 0.0000033 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg19794939 chr11:27494405 11 27494405 LGR4 South shore 0.101 0.0000021 0.0000035 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg03113121 chr19:46366686 19 46366686 FOXA3;SYMPK North shore 0.178 0.0000036 0.0000035 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg23114964 chr1:42217077 1 42217077 HIVEP3 Open sea -0.229 0.0000047 0.0000037 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg06527318 chr1:25349006 1 25349006 - Open sea -0.313 0.0000064 0.0000038 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg20100049 chr11:67979188 11 67979188 SUV420H1 North shore -0.204 0.0000042 0.0000038 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg20515787 chr11:65728726 11 65728726 SART1 Open sea 0.108 0.0000022 0.0000039 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg13680864 chr10:17686119 10 17686119 STAM Island 0.235 0.0000048 0.000004 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg03722643 chr2:105858861 2 105858861 GPR45 Island -0.044 0.00000091 0.0000044 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg23096644 chr7:94284634 7 94284634 SGCE;PEG10 North shore 0.167 0.0000034 0.0000044 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg08707988 chr6:32852998 6 32852998 - Open sea -0.258 0.0000053 0.0000045 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg19857227 chr14:95240340 14 95240340 - Island -0.215 0.0000044 0.0000045 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg09749788 chr8:6519110 8 6519110 - Open sea 0.229 0.0000048 0.0000047 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg06655187 chr17:34842929 17 34842929 ZNHIT3 Island 0.125 0.0000026 0.0000048 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg10800369 chr12:16761930 12 16761930 LMO3 Open sea 0.327 0.0000068 0.0000049 None 33741061_Moccia-C_birthweight_discovery Moccia C NINFEA 33741061 2019-03-21 birthweight EFO_0004344 Discovery Table 3 DNA methylation birthweight age, sex, gestational age, maternal age, parity, maternal pre-pregnancy BMI, maternal education, cell composition (reference based), casecontrol status, batch effects Beta Values grams Illumina HumanMethylation450 Saliva None 135 1 Children Both European cg24864887 chr15:76635638 15 76635638 - South shore 0.347 0.0000072 0.0000049 None 33741061_Moccia-C_birthweight_discovery