author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg01543150	chr3:192634061	3	192634061	MB21D2	North shore	0.112	0.01	0.0000000000007	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg19773937	chr1:60216631	1	60216631	FGGY	Open sea	-0.103	0.01	0.0000000000089	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg23165574	chr9:16510109	9	16510109	BNC2	Open sea	-0.079	0.01	0.000000000013	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg11031221	chr17:70417517	17	70417517	LINC00673	Open sea	-0.081	0.01	0.000000000034	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg04252928	chr16:89168599	16	89168599	ACSF3	South shore	0.205	0.03	0.000000000036	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg22499797	chr17:30585906	17	30585906	-	Open sea	0.054	0.01	0.000000000067	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg22729726	chr1:3123854	1	3123854	PRDM16	Open sea	0.075	0.01	0.00000000017	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg07172149	chr7:136567872	7	136567872	CHRM2	Open sea	-0.104	0.01	0.00000000017	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg13750905	chr16:57832000	16	57832000	KIFC3	North shelf	0.132	0.02	0.00000000017	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg15975895	chr3:178668607	3	178668607	-	Open sea	-0.115	0.02	0.00000000021	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg03479114	chr4:166280725	4	166280725	-	Open sea	-0.11	0.02	0.0000000003	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg00713549	chr7:41670492	7	41670492	-	Open sea	-0.117	0.02	0.0000000003	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg05207048	chr5:167513456	5	167513456	ODZ2	Open sea	0.097	0.01	0.00000000033	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg25466245	chr1:223407095	1	223407095	SUSD4	Open sea	-0.066	0.01	0.00000000034	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg13352096	chr16:57832085	16	57832085	KIFC3	North shelf	0.139	0.02	0.00000000034	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg18817664	chr19:2987337	19	2987337	TLE6	Open sea	0.064	0.01	0.00000000036	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg07051715	chr12:14807587	12	14807587	GUCY2C	Open sea	-0.092	0.01	0.00000000038	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg26299084	chr4:81118588	4	81118588	PRDM8	Island	0.238	0.03	0.00000000047	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg07588775	chr6:148685723	6	148685723	SASH1	Open sea	-0.088	0.01	0.00000000047	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg25236398	chr12:9928325	12	9928325	-	Open sea	-0.109	0.02	0.00000000057	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg09720404	chr9:82416645	9	82416645	-	Open sea	-0.081	0.01	0.00000000058	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg12492273	chr7:2119499	7	2119499	MAD1L1	South shelf	0.109	0.02	0.00000000081	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg10106284	chr2:16847988	2	16847988	FAM49A	Open sea	-0.095	0.01	0.00000000082	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg21940313	chr17:41620911	17	41620911	ETV4	North shore	0.109	0.02	0.00000000083	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg19611364	chr19:13135494	19	13135494	NFIX	Island	0.132	0.02	0.00000000083	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg17389813	chr11:122060265	11	122060265	LOC399959	Open sea	-0.155	0.02	0.00000000096	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg08120188	chr1:230495801	1	230495801	PGBD5	South shelf	0.106	0.02	0.00000000097	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg03984209	chr3:55920018	3	55920018	ERC2	Open sea	-0.1	0.01	0.0000000011	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg02462487	chr11:2920350	11	2920350	SLC22A18AS;SLC22A18	North shelf	-0.078	0.01	0.0000000011	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg08214927	chr14:91765824	14	91765824	CCDC88C	Open sea	0.104	0.01	0.0000000011	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg16887422	chr2:240035107	2	240035107	HDAC4	South shore	0.096	0.01	0.0000000014	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg06268875	chr18:11147385	18	11147385	FAM38B	North shore	0.117	0.02	0.0000000016	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg15391651	chr1:165132273	1	165132273	-	Open sea	0.11	0.02	0.0000000017	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg17138053	chr6:137603455	6	137603455	-	Open sea	0.05	0.01	0.0000000017	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg04688366	chr7:11498627	7	11498627	THSD7A	Open sea	-0.091	0.01	0.0000000017	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg02259914	chr20:3693221	20	3693221	-	Open sea	0.06	0.01	0.0000000018	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg01600165	chr12:62662949	12	62662949	USP15	Open sea	-0.111	0.02	0.0000000018	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg13817952	chr9:124990456	9	124990456	LHX6	Island	0.344	0.05	0.0000000019	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg15159069	chr3:192634089	3	192634089	C3orf59	North shore	0.104	0.01	0.0000000022	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg01001422	chr19:13135631	19	13135631	NFIX	Island	0.102	0.01	0.0000000026	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg27192248	chr15:65285669	15	65285669	-	South shelf	-0.199	0.03	0.0000000034	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg21211039	chr22:45555611	22	45555611	-	North shelf	-0.078	0.01	0.0000000037	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg11054905	chr18:44298961	18	44298961	ST8SIA5	Open sea	-0.084	0.01	0.0000000044	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg27446735	chr1:169435182	1	169435182	SLC19A2	Open sea	0.108	0.02	0.0000000046	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg16586518	chr3:47040214	3	47040214	NBEAL2	Open sea	0.06	0.01	0.0000000048	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg02509576	chr2:68053187	2	68053187	LOC101927701	Open sea	-0.091	0.01	0.000000005	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg08119153	chr14:78913301	14	78913301	NRXN3	Open sea	0.118	0.02	0.0000000057	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg10279736	chr4:40390526	4	40390526	-	Open sea	0.06	0.01	0.0000000061	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg09862081	chr15:49149387	15	49149387	SHC4	Open sea	0.074	0.01	0.0000000063	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg07598481	chr13:72768819	13	72768819	-	Open sea	-0.124	0.02	0.0000000063	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg16055613	chr6:164187401	6	164187401	-	Open sea	-0.093	0.01	0.0000000064	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg18073471	chr4:81119198	4	81119198	PRDM8	Island	0.07	0.01	0.0000000071	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg18238078	chr4:174755501	4	174755501	-	Open sea	0.097	0.01	0.0000000072	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg00268509	chr6:148685438	6	148685438	SASH1	Open sea	-0.112	0.02	0.0000000074	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg16013325	chr14:42898342	14	42898342	-	Open sea	-0.064	0.01	0.0000000078	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg02476619	chr17:19448344	17	19448344	SLC47A1	Open sea	0.045	0.01	0.000000008	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg06795233	chr2:219737392	2	219737392	WNT6	North shore	0.125	0.02	0.0000000083	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg23344395	chr3:192634002	3	192634002	C3orf59	North shore	0.078	0.01	0.0000000083	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg13631444	chr8:110098866	8	110098866	TRHR	Open sea	0.108	0.02	0.0000000097	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg05429921	chr19:13135318	19	13135318	NFIX	Island	0.123	0.02	0.0000000097	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg09022082	chr1:236270585	1	236270585	-	Open sea	-0.065	0.01	0.00000001	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg25406206	chr19:13135352	19	13135352	NFIX	Island	0.139	0.02	0.00000001	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg24791731	chr10:20107785	10	20107785	PLXDC2	South shore	0.124	0.02	0.000000011	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg17077319	chr3:149886667	3	149886667	-	Open sea	0.11	0.02	0.000000012	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg12641545	chr18:7601196	18	7601196	PTPRM	Open sea	-0.138	0.02	0.000000014	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg13108341	chr17:11608711	17	11608711	DNAH9	Open sea	0.169	0.03	0.000000014	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg07097098	chr19:55721638	19	55721638	PTPRH	Open sea	-0.076	0.01	0.000000015	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg08756830	chr2:18518459	2	18518459	-	Open sea	-0.1	0.02	0.000000016	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg14094320	chr1:209578715	1	209578715	-	Open sea	0.061	0.01	0.000000018	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg17661220	chr20:3693179	20	3693179	-	Open sea	0.046	0.01	0.000000018	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg20019675	chr8:48572058	8	48572058	SPIDR	Open sea	-0.085	0.01	0.000000018	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg06815976	chr6:32164816	6	32164816	NOTCH4	South shore	0.086	0.01	0.000000021	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg26378115	chr3:189827024	3	189827024	P3H2	Open sea	0.089	0.01	0.000000021	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg07839457	chr16:57023022	16	57023022	NLRC5	North shore	-0.118	0.02	0.000000022	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg10755723	chr3:192576964	3	192576964	C3orf59	Open sea	0.052	0.01	0.000000023	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg13490403	chr9:124982413	9	124982413	LHX6	Island	-0.134	0.02	0.000000024	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg19550755	chr11:18794896	11	18794896	PTPN5	Open sea	0.059	0.01	0.000000024	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg03463411	chr4:81118188	4	81118188	PRDM8	Island	0.203	0.03	0.000000025	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg25608626	chr11:117362843	11	117362843	DSCAML1	Open sea	0.053	0.01	0.000000025	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg15627357	chr16:57832055	16	57832055	KIFC3	North shelf	0.101	0.02	0.000000025	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg24470086	chr4:158237432	4	158237432	GRIA2	Open sea	-0.123	0.02	0.000000027	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg05468212	chr9:137688136	9	137688136	COL5A1	Open sea	0.047	0.01	0.000000027	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg02773764	chr4:129308389	4	129308389	-	Open sea	-0.078	0.01	0.000000028	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg06373870	chr4:81117853	4	81117853	PRDM8	North shore	0.174	0.03	0.000000031	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg06846279	chr1:116213278	1	116213278	VANGL1	Open sea	0.074	0.01	0.000000031	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg08257257	chr11:68517804	11	68517804	MTL5	Island	0.046	0.01	0.000000032	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg03661817	chr16:57831745	16	57831745	KIFC3	Open sea	0.119	0.02	0.000000033	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg19099872	chr1:232065213	1	232065213	DISC1-IT1;DISC1;TSNAX-DISC1	Open sea	0.08	0.01	0.000000034	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg06307913	chr4:81118794	4	81118794	PRDM8	North shore	0.213	0.03	0.000000035	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg19151852	chr17:79938611	17	79938611	ASPSCR1	South shelf	0.098	0.02	0.000000036	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg13474360	chr3:192603409	3	192603409	MB21D2	Open sea	0.067	0.01	0.000000037	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg06192447	chr11:18815245	11	18815245	PTPN5	South shore	0.051	0.01	0.000000039	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg17976191	chr19:13135527	19	13135527	NFIX	Island	0.25	0.04	0.00000004	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg04965297	chr19:13135329	19	13135329	NFIX	Island	0.122	0.02	0.000000041	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg19664938	chr5:6493258	5	6493258	UBE2QL1	Open sea	-0.068	0.01	0.000000043	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg14547509	chr9:14318498	9	14318498	-	North shelf	-0.075	0.01	0.000000045	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg02274584	chr21:29602444	21	29602444	LOC101927973	Open sea	0.129	0.02	0.000000045	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg11196506	chr14:38760181	14	38760181	-	Open sea	-0.117	0.02	0.000000046	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg01564268	chr17:36666953	17	36666953	ARHGAP23	Island	0.16	0.03	0.000000047	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg03250223	chr3:23248006	3	23248006	UBE2E2	South shelf	0.047	0.01	0.00000005	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg01978236	chr6:32191479	6	32191479	NOTCH4	Open sea	-0.069	0.01	0.000000053	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg08189998	chr6:39439773	6	39439773	KIF6	Open sea	0.042	0.01	0.000000053	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg10129063	chr4:81111385	4	81111385	PRDM8	South shore	0.159	0.03	0.00000006	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg05478824	chr17:79970135	17	79970135	ASPSCR1	South shelf	0.073	0.01	0.000000062	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg17930194	chr9:124982834	9	124982834	LHX6	Island	-0.167	0.03	0.000000065	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg01521220	chr17:46233799	17	46233799	MIR1203;SKAP1	Open sea	0.057	0.01	0.000000065	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg07524540	chr17:15394016	17	15394016	TVP23C-CDRT4	Open sea	-0.1	0.02	0.000000065	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg02329226	chr11:65976788	11	65976788	PACS1	Open sea	0.051	0.01	0.000000068	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg04084749	chr2:187440367	2	187440367	-	Open sea	-0.121	0.02	0.000000069	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg12496433	chr2:16847763	2	16847763	FAM49A	Open sea	-0.087	0.01	0.000000072	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg01693697	chr15:74212896	15	74212896	LOXL1-AS1	Open sea	-0.103	0.02	0.000000074	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg16776685	chr19:46579734	19	46579734	LOC400706	North shore	-0.115	0.02	0.000000074	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg17125362	chr18:8526136	18	8526136	-	Open sea	-0.064	0.01	0.000000074	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg08650597	chr15:101442706	15	101442706	ALDH1A3	Open sea	-0.072	0.01	0.000000075	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg07396746	chr8:23162295	8	23162295	LOXL2	Open sea	0.065	0.01	0.000000076	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg15648792	chr18:11146255	18	11146255	FAM38B	North shelf	0.064	0.01	0.000000078	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg26833883	chr1:154965572	1	154965572	FLAD1;LENEP	Open sea	0.037	0.01	0.000000082	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg25989755	chr4:151134483	4	151134483	DCLK2	Open sea	0.098	0.02	0.000000085	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg10119082	chr7:98990626	7	98990626	ARPC1B	Island	0.227	0.04	0.000000087	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes
Song N	St Jude Lifetime Cohort	33823916	2021-04-06	Cancer treatment: Antimetabolites and asparaginase enzymes	None	None	Table S2	DNA methylation	Cancer treatment: Antimetabolites and asparaginase enzymes	sex, age, other cancer treatment exposures, cell composition (reference based), ancestry (genomic PCs), batch effects	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2052	1	Children	Both	European	cg14193434	chr13:67802884	13	67802884	PCDH9	North shore	0.115	0.02	0.000000087	None	33823916_Song-N_cancer_treatment__antimetabolites_and_asparaginase_enzymes