author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	-0.0018	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	-0.0051	0.00027	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	-0.022	0.0025	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.0025	0.00024	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.0025	0.00022	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.012	0.00046	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.033	0.0021	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.01	0.00037	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.034	0.0018	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.00098	0.00012	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.012	None	6.6e-308	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	0.0031	None	1.2e-137	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.0075	None	6.8e-111	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.174011	0.00829452	2.64709e-96	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.169585	0.00818088	4.177685e-94	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.169574	0.00818114	4.35384e-94	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.207381	0.0101527	1.8351909999999999e-91	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.16755	0.0082831	9.326807999999999e-90	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.162899	0.00817172	2.915629e-87	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.162886	0.00817137	2.9579249999999998e-87	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.161006	0.00814885	8.871163e-86	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.156279	0.00815512	7.276002e-81	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.23325	0.00814	1.8e-71	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.156497	0.0087706	1.809355e-70	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.155485	0.00875402	7.550793999999999e-70	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.150093	0.00876446	4.141337e-65	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	0.0035	None	8.6e-65	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.134221	0.00826559	8.776344e-59	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.134175	0.00826595	9.694066e-59	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.144168	0.00891131	2.307452e-58	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.129235	0.00818733	1.137233e-55	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.28693	0.01288	3.0999999999999996e-55	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-	-	1.52e-52	-	28056824_age_4_vs_age_0
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.125037	0.00819177	3.3598120000000005e-52	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.129421	0.00849994	5.928481e-52	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.128826	0.00848986	1.2940009999999999e-51	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-	-	5.76e-45	-	28056824_age_4_vs_age_0
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.0691	0.004	4.3e-41	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.127976	0.00952164	6.116782e-41	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.11001	0.00820646	9.772200999999999e-41	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.611	0.046	5.7e-40	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.0015	None	1.8999999999999998e-39	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.0033	None	5.4e-39	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	1.186	0.091	7.4e-39	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.887	0.068	9.2e-39	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.16266	0.01016	3e-37	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.108685	0.00873478	2.310171e-35	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.107699	0.00871833	6.98414e-35	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-	-	2.2e-32	-	28056824_age_4_vs_age_0
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	1.16	0.102	6.3000000000000005e-30	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	1.04	0.091	7.999999999999999e-30	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.07357	0.00552	3.5e-29	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.76	0.068	5.7e-29	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.51	0.046	1.1000000000000002e-28	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.107924	0.00988167	1.161856e-27	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.0910049	0.00835841	1.679326e-27	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.089144	0.0082237	2.8259430000000003e-27	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.0871908	0.00821166	3.063084e-26	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.0871068	0.00821256	3.457475e-26	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.0867542	0.00822544	6.489567e-26	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.966	0.094	5.6999999999999995e-25	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ALPI protein levels (SeqId = 17441-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALPI protein levels (SeqId = 17441-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intestinal-type alkaline phosphatase	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.46	0.046	1.8e-23	None	Gadd-DA_alpi_protein_levels__seqid___17441-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ALPI protein levels (SeqId = 17441-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALPI protein levels (SeqId = 17441-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intestinal-type alkaline phosphatase	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.67	0.068	9.7e-23	None	Gadd-DA_alpi_protein_levels__seqid___17441-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.0817612	0.00844375	4.146102e-22	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Raffield LM	The Jackson Heart Study	31985870	2020-01-27	Coagulation factor VIII	EFO_0004634, EFO_0004630	None	Table 5	Coagulation factor VIII	DNA methylation	Cell composition (reference based), batch effects, age, ssex, ancestry (genomic PCs)	None	Beta Values	Illumina HumanMethylationEPIC	Whole blood	None	1670	1	Adults	Both	African	cg21160290	chr9:136149941	9	136149941	ABO	North shore	None	None	5.2e-22	None	31985870_Raffield-LM_coagulation_factor_viii
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.0814483	0.0084392	5.647915e-22	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Raffield LM	The Jackson Heart Study	31985870	2020-01-27	Coagulation factor VIII	EFO_0004634, EFO_0004630	None	Table 5	Coagulation factor VIII	DNA methylation	Cell composition (reference based), batch effects, age, ssex, ancestry (genomic PCs)	None	Beta Values	Illumina HumanMethylationEPIC	Whole blood	None	1670	1	Adults	Both	African	cg12020464	chr9:136131183	9	136131183	ABO	Island	None	None	1.9e-21	None	31985870_Raffield-LM_coagulation_factor_viii
Raffield LM	The Jackson Heart Study	31985870	2020-01-27	Coagulation factor VIII	EFO_0004634, EFO_0004630	None	Table 5	Coagulation factor VIII	DNA methylation	Cell composition (reference based), batch effects, age, ssex, ancestry (genomic PCs)	None	Beta Values	Illumina HumanMethylationEPIC	Whole blood	None	1670	1	Adults	Both	African	cg22535403	chr9:136150032	9	136150032	ABO	Island	None	None	2.4e-21	None	31985870_Raffield-LM_coagulation_factor_viii
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.97	0.103	2.9e-21	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ALPI protein levels (SeqId = 17441-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALPI protein levels (SeqId = 17441-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intestinal-type alkaline phosphatase	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.86	0.091	4.1e-21	None	Gadd-DA_alpi_protein_levels__seqid___17441-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.64	0.068	6.8e-21	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.00067	None	1.4e-20	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.0766756	0.00823226	1.402535e-20	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.722	0.078	2.4e-20	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.42	0.046	9.8e-20	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.83	0.091	1e-19	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 17456-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 17456-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.61	0.068	3e-19	None	Gadd-DA_golm1_protein_levels__seqid___17456-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 17456-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 17456-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.4	0.046	9.3e-18	None	Gadd-DA_golm1_protein_levels__seqid___17456-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.8	0.094	1.7e-17	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00017475	chr9:136131707	9	136131707	ABO	Island	0.0018	None	4.1e-17	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.0701797	0.00839095	6.619778e-17	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	1.061	0.127	7.8e-17	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.00056	0.000069	4.4e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 17456-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 17456-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.74	0.091	6.2e-16	None	Gadd-DA_golm1_protein_levels__seqid___17456-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	1.04	0.129	7.7e-16	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.0013	0.00017	0.0000000000000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.0660292	0.00825128	0.000000000000001312294	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Raffield LM	The Jackson Heart Study	31985870	2020-01-27	Coagulation factor VIII	EFO_0004634, EFO_0004630	None	Table 5	Coagulation factor VIII	DNA methylation	Cell composition (reference based), batch effects, age, ssex, ancestry (genomic PCs)	None	Beta Values	Illumina HumanMethylationEPIC	Whole blood	None	1670	1	Adults	Both	African	cg24267699	chr9:136151359	9	136151359	ABO	Island	None	None	0.0000000000000014	None	31985870_Raffield-LM_coagulation_factor_viii
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.0659616	0.00825193	0.000000000000001409192	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.62	0.078	0.0000000000000019	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ALPI protein levels (SeqId = 17441-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALPI protein levels (SeqId = 17441-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intestinal-type alkaline phosphatase	774	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.61	0.078	0.0000000000000066	None	Gadd-DA_alpi_protein_levels__seqid___17441-4__somascan_protein_measurement
Raffield LM	The Jackson Heart Study	31985870	2020-01-27	Coagulation factor VIII	EFO_0004634, EFO_0004630	None	Table 5	Coagulation factor VIII	DNA methylation	Cell composition (reference based), batch effects, age, ssex, ancestry (genomic PCs)	None	Beta Values	Illumina HumanMethylationEPIC	Whole blood	None	1670	1	Adults	Both	African	cg14440550	chr9:136131118	9	136131118	ABO	Island	None	None	0.0000000000000075	None	31985870_Raffield-LM_coagulation_factor_viii
Gadd DA	Generation Scotland	35945220	31/07/2022	F8 protein levels (SeqId = 13499-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	F8 protein levels (SeqId = 13499-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coagulation factor VIII	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.35	0.046	0.000000000000018	None	Gadd-DA_f8_protein_levels__seqid___13499-30__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.062707	0.00824032	0.00000000000002912572	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.78	0.103	0.000000000000031	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14636261	chr9:136133628	9	136133628	ABO	South shore	0.02794	0.00345	0.000000000000066	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	F8 protein levels (SeqId = 13499-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	F8 protein levels (SeqId = 13499-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coagulation factor VIII	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.68	0.091	0.000000000000075	None	Gadd-DA_f8_protein_levels__seqid___13499-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	F8 protein levels (SeqId = 13499-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	F8 protein levels (SeqId = 13499-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coagulation factor VIII	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.51	0.068	0.00000000000011	None	Gadd-DA_f8_protein_levels__seqid___13499-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ALPI protein levels (SeqId = 17441-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALPI protein levels (SeqId = 17441-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intestinal-type alkaline phosphatase	774	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	-0.76	0.103	0.00000000000012	None	Gadd-DA_alpi_protein_levels__seqid___17441-4__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg14294971	chr9:136134067	9	136134067	ABO	South shelf	-1.878609	0.2567	0.00000000000025	-	27105112_hiv_infection_discovery
Raffield LM	The Jackson Heart Study	31985870	2020-01-27	Coagulation factor VIII	EFO_0004634, EFO_0004630	None	Table 5	Coagulation factor VIII	DNA methylation	Cell composition (reference based), batch effects, age, ssex, ancestry (genomic PCs)	None	Beta Values	Illumina HumanMethylationEPIC	Whole blood	None	1670	1	Adults	Both	African	cg11879188	chr9:136149908	9	136149908	ABO	North shore	None	None	0.00000000000038	None	31985870_Raffield-LM_coagulation_factor_viii
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	2.493005	0.3476	0.000000000000739	-	27105112_hiv_infection_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	ALPI protein levels (SeqId = 17441-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALPI protein levels (SeqId = 17441-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intestinal-type alkaline phosphatase	774	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	-0.67	0.094	0.00000000000083	None	Gadd-DA_alpi_protein_levels__seqid___17441-4__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.03405	0.00455	0.0000000000024	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.024	0.00344	0.0000000000026	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.65	0.094	0.000000000003	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.013	0.0018	0.0000000000041	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.01583	0.00219	0.00000000001	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 17456-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 17456-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.63	0.094	0.000000000012	None	Gadd-DA_golm1_protein_levels__seqid___17456-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.682	0.1	0.000000000012	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 10613-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 10613-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.61	0.091	0.000000000016	None	Gadd-DA_casc4_protein_levels__seqid___10613-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	-0.69	0.103	0.000000000016	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 10613-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 10613-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.46	0.068	0.000000000017	None	Gadd-DA_casc4_protein_levels__seqid___10613-33__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14639822	chr9:136131484	9	136131484	ABO	Island	0.002	None	0.000000000021	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 10613-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 10613-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.31	0.046	0.000000000029	None	Gadd-DA_casc4_protein_levels__seqid___10613-33__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0548362	0.00824415	0.000000000030032	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ISLR2 protein levels (SeqId = 13124-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISLR2 protein levels (SeqId = 13124-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin superfamily containing leucine-rich repeat protein 2	774	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.33	0.051	0.000000000051	None	Gadd-DA_islr2_protein_levels__seqid___13124-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.51	0.078	0.000000000052	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.044	0.0061	0.00000000014	None	32795589_Kyung-WK_eosinophilia_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.0011	None	0.00000000021	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0639913	0.0101042	0.0000000002472166	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg13850847	chr9:136131739	9	136131739	ABO	Island	-0.031	0.00439	0.00000000031	None	32795589_Kyung-WK_eosinophilia_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 17456-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 17456-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.64	0.103	0.00000000033	None	Gadd-DA_golm1_protein_levels__seqid___17456-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ISLR2 protein levels (SeqId = 13124-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISLR2 protein levels (SeqId = 13124-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin superfamily containing leucine-rich repeat protein 2	774	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.59	0.094	0.0000000004	None	Gadd-DA_islr2_protein_levels__seqid___13124-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRC32 protein levels (SeqId = 7551-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRC32 protein levels (SeqId = 7551-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transforming growth factor beta activator LRRC32	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.29	0.046	0.00000000044	None	Gadd-DA_lrrc32_protein_levels__seqid___7551-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.64	0.102	0.00000000047	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRC32 protein levels (SeqId = 7551-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRC32 protein levels (SeqId = 7551-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transforming growth factor beta activator LRRC32	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.42	0.068	0.00000000054	None	Gadd-DA_lrrc32_protein_levels__seqid___7551-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRC32 protein levels (SeqId = 7551-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRC32 protein levels (SeqId = 7551-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transforming growth factor beta activator LRRC32	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.57	0.091	0.00000000055	None	Gadd-DA_lrrc32_protein_levels__seqid___7551-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.57	0.091	0.00000000056	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14636261	chr9:136133628	9	136133628	ABO	South shore	-0.00083	0.00013	0.00000000062	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.732	0.118	0.00000000063	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	F8 protein levels (SeqId = 13499-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	F8 protein levels (SeqId = 13499-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coagulation factor VIII	774	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.48	0.078	0.00000000068	None	Gadd-DA_f8_protein_levels__seqid___13499-30__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.053708	0.00871384	0.0000000007300216	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14636261	chr9:136133628	9	136133628	ABO	South shore	0.001	None	0.0000000012	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.01	0.0017	0.0000000016	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	ISLR2 protein levels (SeqId = 13124-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISLR2 protein levels (SeqId = 13124-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin superfamily containing leucine-rich repeat protein 2	774	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	-0.61	0.103	0.0000000024	None	Gadd-DA_islr2_protein_levels__seqid___13124-20__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14636261	chr9:136133628	9	136133628	ABO	South shore	0.048841	0.00824672	0.000000003242105	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 17456-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 17456-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.46	0.078	0.0000000042	None	Gadd-DA_golm1_protein_levels__seqid___17456-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	F8 protein levels (SeqId = 13499-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	F8 protein levels (SeqId = 13499-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coagulation factor VIII	774	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.55	0.094	0.0000000048	None	Gadd-DA_f8_protein_levels__seqid___13499-30__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14639822	chr9:136131484	9	136131484	ABO	Island	-0.00046	0.000079	0.0000000053	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Raffield LM	The Jackson Heart Study	31985870	2020-01-27	Coagulation factor VIII	EFO_0004634, EFO_0004630	None	Table 5	Coagulation factor VIII	DNA methylation	Cell composition (reference based), batch effects, age, ssex, ancestry (genomic PCs)	None	Beta Values	Illumina HumanMethylationEPIC	Whole blood	None	1670	1	Adults	Both	African	cg13506600	chr9:136150361	9	136150361	ABO	Island	None	None	0.0000000078	None	31985870_Raffield-LM_coagulation_factor_viii
Gadd DA	Generation Scotland	35945220	31/07/2022	ADGRF5 protein levels (SeqId = 6409-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADGRF5 protein levels (SeqId = 6409-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adhesion G protein-coupled receptor F5	774	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.29	0.051	0.0000000083	None	Gadd-DA_adgrf5_protein_levels__seqid___6409-57__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14639822	chr9:136131484	9	136131484	ABO	Island	0.00052	None	0.0000000084	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.74	0.129	0.00000001	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0494213	0.00875302	0.000000016708	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.53	0.094	0.000000019	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0485907	0.00872942	0.00000002647401	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	ALPI protein levels (SeqId = 17441-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALPI protein levels (SeqId = 17441-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intestinal-type alkaline phosphatase	774	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	-0.7	0.129	0.00000005	None	Gadd-DA_alpi_protein_levels__seqid___17441-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14636261	chr9:136133628	9	136133628	ABO	South shore	0.0442432	0.00824849	0.00000008272489	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00017475	chr9:136131707	9	136131707	ABO	Island	0.0053	None	0.000000099	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13850847	chr9:136131739	9	136131739	ABO	Island	0.0016	None	0.00000012	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0461584	0.00873139	0.0000001264757	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.63	0.119	0.00000013	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0432206	0.00824886	0.0000001631686	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Aslibekyan S	CHARGE	29617535	2018-04-04	Tumour necrosis factor-alpha	EFO_0003271	Meta-analysis model 3	Table 2	DNA methylation	Tumour necrosis factor-alpha	Age, sex, batch effects, cell composition (reference based), smoking, body mass index	Beta Values	pg/ml	Illumina HumanMethylation450	Whole blood	Some associations replicated - see paper	4163	5	Adults	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.009	0.002	0.00000017	None	29617535_Aslibekyan-S_tumour_necrosis_factor-alpha_meta-analysis_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.35	0.068	0.0000002	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.0426888	0.00824904	0.000000230919	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Aslibekyan S	CHARGE	29617535	2018-04-04	Tumour necrosis factor-alpha	EFO_0003271	Meta-analysis model 2	eTable 3	DNA methylation	Tumour necrosis factor-alpha	Age, sex, batch effects, cell composition (reference based)	Beta Values	pg/ml	Illumina HumanMethylation450	Whole blood	None	4163	5	Adults	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.009	0.002	0.00000024	None	29617535_Aslibekyan-S_tumour_necrosis_factor-alpha_meta-analysis_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.26	0.051	0.00000027	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.24	0.046	0.00000029	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14636261	chr9:136133628	9	136133628	ABO	South shore	0.0423206	0.00824917	0.0000002929939	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	0.476	0.094	0.00000041	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.0416955	0.00824939	0.0000004369984	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRC32 protein levels (SeqId = 7551-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRC32 protein levels (SeqId = 7551-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transforming growth factor beta activator LRRC32	774	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.47	0.093	0.00000049	None	Gadd-DA_lrrc32_protein_levels__seqid___7551-33__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.0414243	0.00824948	0.0000005188656	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CDH17 protein levels (SeqId = 16613-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDH17 protein levels (SeqId = 16613-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cadherin-17	774	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.471	0.094	0.00000057	None	Gadd-DA_cdh17_protein_levels__seqid___16613-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DPEP2 protein levels (SeqId = 8327-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPEP2 protein levels (SeqId = 8327-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dipeptidase 2	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.23	0.046	0.00000062	None	Gadd-DA_dpep2_protein_levels__seqid___8327-26__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.016	0.0031	0.00000067	None	33450751_Mulder-RH_sex_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	EPHA4 protein levels (SeqId = 16288-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPHA4 protein levels (SeqId = 16288-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ephrin type-A receptor 4	774	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.47	0.094	0.00000072	None	Gadd-DA_epha4_protein_levels__seqid___16288-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 10613-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 10613-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.51	0.103	0.00000075	None	Gadd-DA_casc4_protein_levels__seqid___10613-33__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.0976042	0.0197743	0.0000008051787	None	39706196_Hannah-M.-Smith_body_fat_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	ALPI protein levels (SeqId = 17441-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALPI protein levels (SeqId = 17441-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intestinal-type alkaline phosphatase	774	1	Adults (18-65 years)	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	-0.58	0.119	0.00000095	None	Gadd-DA_alpi_protein_levels__seqid___17441-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	-0.63	0.129	0.000001	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ABO protein levels (SeqId = 9253-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ABO protein levels (SeqId = 9253-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histo-blood group ABO system transferase	774	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.49	0.102	0.0000013	None	Gadd-DA_abo_protein_levels__seqid___9253-52__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20955080	chr9:136152049	9	136152049	ABO	South shore	-0.039868	0.00825001	0.000001362062	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.49	0.102	0.0000014	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.0406507	0.00842814	0.00000142686	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.0951484	0.0197297	0.000001429145	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20955080	chr9:136152049	9	136152049	ABO	South shore	-0.0402153	0.00835264	0.000001489107	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.012	0.0024	0.0000016	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0395182	0.00825012	0.000001683977	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.57	0.119	0.0000017	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.0393965	0.00825016	0.000001812252	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.00035979	7.51e-05	0.00000188	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	DPEP2 protein levels (SeqId = 8327-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPEP2 protein levels (SeqId = 8327-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dipeptidase 2	774	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	-0.45	0.094	0.000002	None	Gadd-DA_dpep2_protein_levels__seqid___8327-26__somascan_protein_measurement
Battram T	GEO	27886173	2020-09-15	Ulcerative colitis	EFO_0000729	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Ulcerative colitis	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	163	1	Adults	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.0492	0.00993	0.000002	None	27886173_Battram-T_ulcerative_colitis_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20955080	chr9:136152049	9	136152049	ABO	South shore	-0.0391278	0.00824201	0.000002080378	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20955080	chr9:136152049	9	136152049	ABO	South shore	-0.0391104	0.0082422	0.000002103248	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 10613-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 10613-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.44	0.094	0.0000024	None	Gadd-DA_casc4_protein_levels__seqid___10613-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DPEP2 protein levels (SeqId = 8327-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPEP2 protein levels (SeqId = 8327-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dipeptidase 2	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.32	0.068	0.0000025	None	Gadd-DA_dpep2_protein_levels__seqid___8327-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	0.44	0.094	0.0000027	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg00017475	chr9:136131707	9	136131707	ABO	Island	-0.156584	0.0333776	0.000002734729	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRC32 protein levels (SeqId = 7551-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRC32 protein levels (SeqId = 7551-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transforming growth factor beta activator LRRC32	774	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.37	0.078	0.0000028	None	Gadd-DA_lrrc32_protein_levels__seqid___7551-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ABO protein levels (SeqId = 9253-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ABO protein levels (SeqId = 9253-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histo-blood group ABO system transferase	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.42	0.09	0.0000028	None	Gadd-DA_abo_protein_levels__seqid___9253-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL3RA protein levels (SeqId = 13744-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL3RA protein levels (SeqId = 13744-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-3 receptor subunit alpha	774	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.24	0.051	0.0000036	None	Gadd-DA_il3ra_protein_levels__seqid___13744-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	-0.47	0.102	0.000004	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	-0.0436885	0.00950271	0.000004312064	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14639822	chr9:136131484	9	136131484	ABO	Island	-0.00149	0.00032	0.0000044	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.037864	0.00825065	0.000004485962	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ALPI protein levels (SeqId = 17441-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALPI protein levels (SeqId = 17441-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intestinal-type alkaline phosphatase	774	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	-0.46	0.102	0.0000048	None	Gadd-DA_alpi_protein_levels__seqid___17441-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	-0.0459052	0.0100362	0.000004825523	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	0.037713	0.0082507	0.000004896414	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0393168	0.00863499	0.000005326081	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.0374461	0.00825078	0.000005710851	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CDH17 protein levels (SeqId = 16613-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDH17 protein levels (SeqId = 16613-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cadherin-17	774	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.231	0.051	0.0000059	None	Gadd-DA_cdh17_protein_levels__seqid___16613-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ISLR2 protein levels (SeqId = 13124-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISLR2 protein levels (SeqId = 13124-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin superfamily containing leucine-rich repeat protein 2	774	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	-0.58	0.129	0.000006	None	Gadd-DA_islr2_protein_levels__seqid___13124-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ENG protein levels (SeqId = 4908-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ENG protein levels (SeqId = 4908-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endoglin	774	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.23	0.051	0.0000062	None	Gadd-DA_eng_protein_levels__seqid___4908-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EPHA4 protein levels (SeqId = 16288-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPHA4 protein levels (SeqId = 16288-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ephrin type-A receptor 4	774	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.23	0.051	0.0000065	None	Gadd-DA_epha4_protein_levels__seqid___16288-17__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.0370658	0.00825761	0.000007220962	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	ABO protein levels (SeqId = 9253-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ABO protein levels (SeqId = 9253-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histo-blood group ABO system transferase	774	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.45	0.101	0.0000081	None	Gadd-DA_abo_protein_levels__seqid___9253-52__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.0368456	0.00826075	0.000008244663	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0388337	0.00874999	0.000009140039	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	0.006	0.0014	0.0000096	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	ICAM5 protein levels (SeqId = 5124-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ICAM5 protein levels (SeqId = 5124-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intercellular adhesion molecule 5	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.2	0.046	0.00001	None	Gadd-DA_icam5_protein_levels__seqid___5124-69__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 17456-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 17456-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.57	0.129	0.000011	None	Gadd-DA_golm1_protein_levels__seqid___17456-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.35	0.078	0.000011	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.0362213	0.00825115	0.00001142214	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.0361461	0.00825118	0.00001191083	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.0358799	0.00825126	0.00001380513	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	QSOX2 protein levels (SeqId = 8397-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QSOX2 protein levels (SeqId = 8397-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfhydryl oxidase 2	774	1	Adults (18-65 years)	Both	European	cg14636261	chr9:136133628	9	136133628	ABO	South shore	0.971	0.224	0.000014	None	Gadd-DA_qsox2_protein_levels__seqid___8397-147__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.0363479	0.00838739	0.00001476441	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 17456-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 17456-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.52	0.119	0.000015	None	Gadd-DA_golm1_protein_levels__seqid___17456-53__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	-0.0933519	0.0215936	0.00001546962	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	FUT10 protein levels (SeqId = 7156-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FUT10 protein levels (SeqId = 7156-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-(1,3)-fucosyltransferase 10	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.395	0.091	0.000016	None	Gadd-DA_fut10_protein_levels__seqid___7156-2__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.02102	0.00479	0.000019	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 10613-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 10613-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.33	0.078	0.00002	None	Gadd-DA_casc4_protein_levels__seqid___10613-33__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.013	0.003	0.00002	None	33450751_Mulder-RH_sex_discovery
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	2.1	0.495	0.00002	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Carmona JJ	Normative Aging Study	30343628	2018-10-21	Lung function decline	EFO_0004314, EFO_0003892	Discovery. FEV1. Lung function decline in this paper is defined as a decrease in FEV1 between visits.	Table S1	Lung function decline	DNA methylation	Season, follow up time, batch effects, weight, weight squared, log(height), age, vitamin C intake, years of education, taking corticosteroids or beta-2-adrenergic agonists or AHFS or LAMA, smoking	L/s	Beta Values	Illumina HumanMethylation450	Whole blood	None	633	1	Adults	Males	European	cg00017475	chr9:136131707	9	136131707	ABO	Island	0.236	0.0556	0.000021	None	30343628_Carmona-JJ_lung_function_decline_discovery__fev1__lung_function_decline_in_this_paper_is_defined_as_a_decrease_in_fev1_between_visits_
Gadd DA	Generation Scotland	35945220	31/07/2022	ADGRF5 protein levels (SeqId = 6409-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADGRF5 protein levels (SeqId = 6409-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adhesion G protein-coupled receptor F5	774	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.4	0.094	0.000021	None	Gadd-DA_adgrf5_protein_levels__seqid___6409-57__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 10613-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 10613-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg14636261	chr9:136133628	9	136133628	ABO	South shore	0.96	0.226	0.000021	None	Gadd-DA_casc4_protein_levels__seqid___10613-33__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07025194	chr9:136135498	9	136135498	ABO	South shelf	0.0351084	0.00825148	0.00002105358	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.0349306	0.00825153	0.00002317675	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	AMY2A protein levels (SeqId = 18917-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AMY2A protein levels (SeqId = 18917-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pancreatic alpha-amylase	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.39	0.091	0.000025	None	Gadd-DA_amy2a_protein_levels__seqid___18917-53__somascan_protein_measurement
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.0004947	0.00011726	0.0000266	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.0430076	0.0102387	0.00002679074	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM3D protein levels (SeqId = 13102-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM3D protein levels (SeqId = 13102-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM3D	774	1	Adults (18-65 years)	Both	European	cg14636261	chr9:136133628	9	136133628	ABO	South shore	0.95	0.227	0.000027	None	Gadd-DA_fam3d_protein_levels__seqid___13102-1__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13850847	chr9:136131739	9	136131739	ABO	Island	-0.00093	0.00022	0.000028	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	chlordane	None	discovery	10.5281/zenodo.5156585	DNA methylation	chlordane	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	1132	1	Adults	Males	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	0.04174	0.01	0.000029	None	34516295_Hoang_chlordane_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07025194	chr9:136135498	9	136135498	ABO	South shelf	-0.0344849	0.00825166	0.00002943052	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.0344107	0.00825168	0.00003061496	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ISLR2 protein levels (SeqId = 13124-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISLR2 protein levels (SeqId = 13124-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin superfamily containing leucine-rich repeat protein 2	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.38	0.091	0.000032	None	Gadd-DA_islr2_protein_levels__seqid___13124-20__somascan_protein_measurement
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.00052926	0.00012772	0.0000369	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	PNLIP protein levels (SeqId = 15613-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PNLIP protein levels (SeqId = 15613-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pancreatic triacylglycerol lipase	774	1	Adults (18-65 years)	Both	European	cg12020464	chr9:136131183	9	136131183	ABO	Island	-0.21	0.051	0.000037	None	Gadd-DA_pnlip_protein_levels__seqid___15613-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07025194	chr9:136135498	9	136135498	ABO	South shelf	0.0339943	0.0082518	0.00003815806	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	-0.0358315	0.00871605	0.00003961355	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PRSS1 protein levels (SeqId = 3049-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRSS1 protein levels (SeqId = 3049-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Trypsin-1	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.38	0.091	0.00004	None	Gadd-DA_prss1_protein_levels__seqid___3049-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DPEP2 protein levels (SeqId = 8327-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPEP2 protein levels (SeqId = 8327-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dipeptidase 2	774	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.32	0.078	0.000041	None	Gadd-DA_dpep2_protein_levels__seqid___8327-26__somascan_protein_measurement
Battram T	GEO	27886173	2020-09-15	Ulcerative colitis	EFO_0000729	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Ulcerative colitis	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	163	1	Adults	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	-0.0264	0.00623	0.000041	None	27886173_Battram-T_ulcerative_colitis_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Gadd DA	Generation Scotland	35945220	31/07/2022	PDGFRA protein levels (SeqId = 10366-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDGFRA protein levels (SeqId = 10366-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet-derived growth factor receptor alpha	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.37	0.091	0.000041	None	Gadd-DA_pdgfra_protein_levels__seqid___10366-11__somascan_protein_measurement
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	chlordane	None	discovery	10.5281/zenodo.5156585	DNA methylation	chlordane	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	1132	1	Adults	Males	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	0.04093	0.01	0.00005	None	34516295_Hoang_chlordane_discovery
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.199126	0.0492	0.0000519	-	27105112_hiv_infection_neutrophils
Gadd DA	Generation Scotland	35945220	31/07/2022	MAN1A2 protein levels (SeqId = 9077-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAN1A2 protein levels (SeqId = 9077-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.37	0.091	0.000052	None	Gadd-DA_man1a2_protein_levels__seqid___9077-10__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.106807	0.0264151	0.00005290953	None	39706196_Hannah-M.-Smith_body_fat_discovery
Kazmi N	PACE	31230546	2019-06-24	Hypertensive disorders of pregnancy	MONDO_0024664, EFO_0000537, EFO_0000668	Meta analysis unadjusted model	Table S3	DNA methylation	Hypertensive disorders of pregnancy	None	Beta Values	None	Illumina HumanMethylation450	Cord blood	None	5242	10	Infants	Both	Unclear	cg14440550	chr9:136131118	9	136131118	ABO	Island	0.0069	0.0017	0.000057	None	31230546_Kazmi-N_hypertensive_disorders_of_pregnancy_meta_analysis_unadjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	FLT4 protein levels (SeqId = 16035-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FLT4 protein levels (SeqId = 16035-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vascular endothelial growth factor receptor 3	774	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	-0.52	0.129	0.000058	None	Gadd-DA_flt4_protein_levels__seqid___16035-8__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07025194	chr9:136135498	9	136135498	ABO	South shelf	0.0331882	0.00825202	0.00005803815	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 10613-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 10613-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.52	0.129	0.000061	None	Gadd-DA_casc4_protein_levels__seqid___10613-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ICAM5 protein levels (SeqId = 5124-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ICAM5 protein levels (SeqId = 5124-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intercellular adhesion molecule 5	774	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.27	0.068	0.000061	None	Gadd-DA_icam5_protein_levels__seqid___5124-69__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.0329949	0.00823134	0.00006142229	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	2	0.494	0.000065	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.00045309	0.00011303	0.0000653	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0400688	0.0100381	0.00006592589	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	FUT10 protein levels (SeqId = 7156-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FUT10 protein levels (SeqId = 7156-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-(1,3)-fucosyltransferase 10	774	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	0.41	0.103	0.000067	None	Gadd-DA_fut10_protein_levels__seqid___7156-2__somascan_protein_measurement
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	1.1	0.271	0.000068	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07241568	chr9:136150823	9	136150823	ABO	Island	0.119934	0.0301182	0.00006859153	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07025194	chr9:136135498	9	136135498	ABO	South shelf	0.0327178	0.00825215	0.00007381943	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.0326208	0.00824828	0.00007693935	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14294971	chr9:136134067	9	136134067	ABO	South shelf	-0.0426	0.01054	0.000077	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22535403	chr9:136150032	9	136150032	ABO	Island	-0.0319911	0.00809242	0.00007746855	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	GOLM1 protein levels (SeqId = 8983-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOLM1 protein levels (SeqId = 8983-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Golgi membrane protein 1	774	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	0.37	0.094	0.000078	None	Gadd-DA_golm1_protein_levels__seqid___8983-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ABO protein levels (SeqId = 9253-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ABO protein levels (SeqId = 9253-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histo-blood group ABO system transferase	774	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	0.37	0.093	0.000079	None	Gadd-DA_abo_protein_levels__seqid___9253-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EPHA4 protein levels (SeqId = 16288-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPHA4 protein levels (SeqId = 16288-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ephrin type-A receptor 4	774	1	Adults (18-65 years)	Both	European	cg21160290	chr9:136149941	9	136149941	ABO	North shore	-0.18	0.046	0.000082	None	Gadd-DA_epha4_protein_levels__seqid___16288-17__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.0324128	0.00825223	0.00008613192	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11698867	chr9:136150802	9	136150802	ABO	Island	-0.0323687	0.00825225	0.00008806441	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06818865	chr9:136151958	9	136151958	ABO	South shore	0.0056	0.0014	0.000089	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	-0.035005	0.00894099	0.00009077096	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_4
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	chlordane	None	discovery	10.5281/zenodo.5156585	DNA methylation	chlordane	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	1132	1	Adults	Males	European	cg13506600	chr9:136150361	9	136150361	ABO	Island	0.00708	0.0018	0.000092	None	34516295_Hoang_chlordane_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	ACE protein levels (SeqId = 10714-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACE protein levels (SeqId = 10714-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Angiotensin-converting enzyme	774	1	Adults (18-65 years)	Both	European	cg14440550	chr9:136131118	9	136131118	ABO	Island	-0.37	0.094	0.000093	None	Gadd-DA_ace_protein_levels__seqid___10714-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TIE1 protein levels (SeqId = 2844-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TIE1 protein levels (SeqId = 2844-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase receptor Tie-1	774	1	Adults (18-65 years)	Both	European	cg24267699	chr9:136151359	9	136151359	ABO	Island	0.36	0.091	0.000093	None	Gadd-DA_tie1_protein_levels__seqid___2844-53__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12855781	chr9:136150585	9	136150585	ABO	Island	0.0322073	0.00825229	0.00009550015	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXND1 protein levels (SeqId = 19561-216)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXND1 protein levels (SeqId = 19561-216)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-D1	774	1	Adults (18-65 years)	Both	European	cg11879188	chr9:136149908	9	136149908	ABO	North shore	-0.37	0.094	0.000097	None	Gadd-DA_plxnd1_protein_levels__seqid___19561-216__somascan_protein_measurement