author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg11423443	chr1:156266465	1	156266465	C1orf85	Open sea	0.04977	0.00243	2.6e-50	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg27228868	chr1:156262783	1	156262783	C1orf85	South shore	0.0333	0.00184	2.0999999999999997e-43	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2438093 (gene symbol: C1orf85)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2438093 (gene symbol: C1orf85)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg25133887	chr1:156266750	1	156266750	C1orf85	Open sea	None	None	3.9e-26	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2438093__gene_symbol__c1orf85__meta-analysis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2438016 (gene symbol: PAQR6)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2438016 (gene symbol: PAQR6)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg25133887	chr1:156266750	1	156266750	C1orf85	Open sea	None	None	2e-18	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2438016__gene_symbol__paqr6__meta-analysis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg25133887	chr1:156266750	1	156266750	C1orf85	Open sea	0.02509	0.00261	4.3e-18	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg22377142	chr1:156265275	1	156265275	C1orf85	South shelf	0.01494	0.00161	3.6e-17	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27228868	chr1:156262783	1	156262783	C1orf85	South shore	0.00065	None	0.000000000000012	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg06794398	chr1:156265456	1	156265456	C1orf85	Open sea	0.015	0.002	0.000000000000209	-	23334450_rheumatoid_arthritis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25133887	chr1:156266750	1	156266750	C1orf85	Open sea	-0.0008	0.00011	0.0000000000036	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22377142	chr1:156265275	1	156265275	C1orf85	South shelf	-0.00034	0.000049	0.0000000000044	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg22377142	chr1:156265275	1	156265275	C1orf85	South shelf	0.01176	0.0017	0.00000000000497	-	23334450_rheumatoid_arthritis
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg11423443	chr1:156266465	1	156266465	C1orf85	Open sea	-1.846583	0.2912	0.000000000227	-	27105112_hiv_infection_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg00713925	chr1:156265511	1	156265511	C1orf85	Open sea	0.007	0.00112	0.0000000022	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27228868	chr1:156262783	1	156262783	C1orf85	South shore	-0.00046	0.000082	0.000000022	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27228868	chr1:156262783	1	156262783	C1orf85	South shore	0.002	None	0.000000023	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg00713925	chr1:156265511	1	156265511	C1orf85	Open sea	0.00684	0.0013	0.000000113	-	23334450_rheumatoid_arthritis
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg22377142	chr1:156265275	1	156265275	C1orf85	South shelf	-0.00053	0.00012	0.000011	None	33564054_Kashima-K_gestational_age
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg20963814	chr1:156265453	1	156265453	C1orf85	Open sea	-1.052721	0.242	0.0000136	-	27105112_hiv_infection_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	SELL protein levels (SeqId = 4831-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SELL protein levels (SeqId = 4831-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: L-selectin	774	1	Adults (18-65 years)	Both	European	cg22377142	chr1:156265275	1	156265275	C1orf85	South shelf	-0.83	0.192	0.000017	None	Gadd-DA_sell_protein_levels__seqid___4831-4__somascan_protein_measurement
Battram T	GEO	30529013	2020-11-01	Melanoma	EFO_0000756	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE120878. Authors assessed methylation differences between melanoma samples and nevi	None	DNA methylation	Melanoma	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Skin	None	162	1	Adults	Both	Unclear	cg27228868	chr1:156262783	1	156262783	C1orf85	South shore	0.082	0.0203	0.000082	None	30529013_Battram-T_melanoma_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse120878__authors_assessed_methylation_differences_between_melanoma_samples_and_nevi
Soloman O	-	28556291	2017-01-09	Prenatal phthalate exposure	CHEBI_26092	26 weeks gestation	Table S2	DNA methylation	Prenatal phthalate exposure	Pre-pregnancy body mass index, parity, years in USA, creatinine, cell counts and technical covariates	M values	mug/l	Illumina HumanMethylation450	Cord blood	Regression coefficients are per 10-fold increase in phthalate	332	1	0	Both	Admixed	cg00713925	chr1:156265511	1	156265511	C1orf85	Open sea	0.14933766	0.038212	0.000093	MCNP	28556291_prenatal_phthalate_exposure_26_weeks_gestation