author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01198184	chr14:103433908	14	103433908	CDC42BPB	South shelf	-0.0011	0.000097	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01333131	chr14:103524584	14	103524584	CDC42BPB	South shore	0.00095	0.000098	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	-0.00087	0.000079	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0023	0.000096	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02995680	chr14:103430766	14	103430766	CDC42BPB	Island	-0.002	0.00012	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0033	0.00019	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.01	0.0012	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04569190	chr14:103422560	14	103422560	CDC42BPB	Open sea	-0.00085	0.000089	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	0.0029	0.00013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-0.0076	0.00083	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0057	0.00021	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.015	0.0014	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0022	0.00021	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0043	0.00013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0094	0.0009	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10087771	chr14:103399429	14	103399429	CDC42BPB	South shelf	-0.0018	0.0002	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10508852	chr14:103404960	14	103404960	CDC42BPB	North shore	-0.0017	0.00019	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11741956	chr14:103438353	14	103438353	CDC42BPB	Open sea	-0.00092	0.000089	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.002	0.00013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0036	0.00022	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13231302	chr14:103467798	14	103467798	CDC42BPB	Open sea	-0.00055	0.000056	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0049	0.00025	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.016	0.0017	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14448215	chr14:103465967	14	103465967	CDC42BPB	Open sea	-0.0017	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.0043	0.00019	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.012	0.0011	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16561957	chr14:103430940	14	103430940	CDC42BPB	South shore	-0.0014	0.00011	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18733798	chr14:103469879	14	103469879	CDC42BPB	Open sea	-0.0028	0.00022	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19561503	chr14:103433986	14	103433986	CDC42BPB	South shelf	-0.002	0.00023	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0038	0.00032	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.0013	0.00011	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22897701	chr14:103432870	14	103432870	CDC42BPB	South shelf	-0.0016	0.00016	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24726553	chr14:103431560	14	103431560	CDC42BPB	South shore	-0.00078	0.000093	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24755931	chr14:103407195	14	103407195	CDC42BPB	South shore	-0.003	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.0034	0.0002	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	-0.0035	0.00021	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26975587	chr14:103430286	14	103430286	CDC42BPB	North shore	-0.00079	0.000076	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.67579	0.00456	8.4e-201	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02855302	chr14:103453791	14	103453791	CDC42BPB	Open sea	0.60659	0.00829	9.999999999999999e-143	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	0.46317	0.00638	5.2e-142	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.43924	0.00615	1.1e-140	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12116939	chr14:103523919	14	103523919	CDC42BPB	Island	0.00014	None	2.1e-140	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14003974	chr14:103497991	14	103497991	CDC42BPB	Open sea	0.58948	0.00835	7.5e-140	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg25059541	chr14:103411459	14	103411459	CDC42BPB	Open sea	0.25399	0.00361	1.6e-139	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	0.29319	0.00445	2.9e-134	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.64022	0.0102	2.3e-130	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.41607	0.00678	1.6e-128	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.32239	0.00534	3.1999999999999998e-127	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.33946	0.00586	6.3e-124	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg27028800	chr14:103411330	14	103411330	CDC42BPB	Open sea	0.23597	0.00441	8.7e-118	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	0.13375	0.00262	5.4e-114	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	0.00027	None	2.5999999999999998e-107	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.1919	0.00419	1.3e-105	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.24107	0.00535	2.4e-104	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.14608	0.00351	2.2e-98	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.20734	0.00515	7.0999999999999995e-96	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.003	None	1.1999999999999999e-95	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.169967	0.00813644	1.626324e-95	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.163806	0.00814505	9.246204e-89	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-	-	1.03e-86	-	28056824_age_4_vs_age_0
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.20574	0.00579	1.3e-86	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13231302	chr14:103467798	14	103467798	CDC42BPB	Open sea	0.10489	0.00343	6.7e-76	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18733798	chr14:103469879	14	103469879	CDC42BPB	Open sea	0.14821	0.00486	1.0999999999999999e-75	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10124651	chr14:103523278	14	103523278	CDC42BPB	Island	0.00024	None	2.0000000000000002e-75	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.148796	0.00816466	2.129796e-73	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.14772	0.00816599	2.34841e-72	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.146456	0.00816754	3.846348e-71	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.146418	0.00816759	4.184737e-71	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-	-	1.48e-69	-	28056824_age_4_vs_age_0
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02995680	chr14:103430766	14	103430766	CDC42BPB	Island	0.0015	None	5.0000000000000005e-68	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01333131	chr14:103524584	14	103524584	CDC42BPB	South shore	0.04618	0.00171	1.3000000000000001e-67	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26975587	chr14:103430286	14	103430286	CDC42BPB	North shore	0.21049	0.00778	1.4e-67	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	3.2	0.182	3e-67	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16561957	chr14:103430940	14	103430940	CDC42BPB	South shore	0.0013	None	1.0000000000000001e-66	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.14082	0.0081743	7.383484e-66	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.06351	0.00249	9.1e-64	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.136468	0.00817933	6.316279e-62	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.09842	0.00413	2e-59	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.132772	0.00818347	1.097822e-58	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.130918	0.00818551	4.285887e-57	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.130769	0.00818567	5.733792e-57	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0015	None	5.9e-57	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.130302	0.00818618	1.429012e-56	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.128743	0.00818786	2.944455e-55	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	3.5	0.227	3.1e-54	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.05031	0.00248	8.7e-50	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.121436	0.00819547	2.569482e-49	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.120029	0.00819688	3.2584800000000003e-48	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg25059541	chr14:103411459	14	103411459	CDC42BPB	Open sea	-2.14677	0.07061	4.04e-48	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.123942	0.00848637	5.681503999999999e-48	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05734220	chr14:103524410	14	103524410	CDC42BPB	Island	0.0357	0.00185	7.099999999999999e-47	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	-0.04413	0.0023	1.1e-46	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10239600	chr14:103411866	14	103411866	CDC42BPB	Open sea	0.034	0.00178	2e-46	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.116344	0.0082005	2.187842e-45	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.115876	0.00820095	4.928401e-45	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	2.21632	0.08112	1.83e-44	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	2.41949	0.09086	1.36e-43	-	25282492_fetal_vs_adult_liver
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	-0.03938	0.0022	5.499999999999999e-43	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.113092	0.0082036	5.757592e-43	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg13231302	chr14:103467798	14	103467798	CDC42BPB	Open sea	3.10501	0.1236	1.21e-41	-	25282492_fetal_vs_adult_liver
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	0.0015	None	2.3999999999999997e-41	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.110662	0.00820586	3.341446e-41	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.110188	0.0082063	7.302576e-41	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.113685	0.00858213	7.989266e-40	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.107157	0.00820903	9.973022000000001e-39	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg06609295	chr14:103400081	14	103400081	CDC42BPB	South shelf	0.029	0.00177	2.1e-38	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	2.54689	0.1126	3.37e-38	-	25282492_fetal_vs_adult_liver
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg02855302	chr14:103453791	14	103453791	CDC42BPB	Open sea	-	-	6.48e-38	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.1044	0.00821145	7.745316e-37	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.104399	0.00821145	7.7489e-37	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.104375	0.00821147	8.044652e-37	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10291119	chr14:103403760	14	103403760	CDC42BPB	North shelf	0.01578	0.00101	4.2000000000000005e-36	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-	-	5.53e-36	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.102968	0.00821268	7.089273999999999e-36	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01333131	chr14:103524584	14	103524584	CDC42BPB	South shore	0.001	None	1.4e-35	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.102523	0.00821306	1.402153e-35	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.104424	0.00845186	6.815119e-35	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04899282	chr14:103523516	14	103523516	CDC42BPB	Island	0.03265	0.00216	1.8e-34	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.100395	0.00821486	3.516102e-34	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0988596	0.00821613	3.441193e-33	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0974123	0.0082173	2.861619e-32	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0971756	0.0082175	4.034537e-32	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0959734	0.00821846	2.278974e-31	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11741956	chr14:103438353	14	103438353	CDC42BPB	Open sea	0.00088	None	4.3e-31	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18211157	chr14:103469613	14	103469613	CDC42BPB	Open sea	-0.02271	0.00164	7.6e-31	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12116939	chr14:103523919	14	103523919	CDC42BPB	Island	0.0004	None	8.7e-31	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0436	0.00323	1.0000000000000001e-29	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.01501	0.00133	1.3e-29	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0927891	0.00822095	2.0138790000000002e-29	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18733798	chr14:103469879	14	103469879	CDC42BPB	Open sea	0.0021	None	2.1e-29	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.097075	0.00863375	3.276735e-29	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.00831	0.00075	1.3000000000000002e-28	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0912256	0.00822214	1.7199870000000002e-28	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19589358	chr14:103410516	14	103410516	CDC42BPB	South shelf	0.03048	0.00234	2.7000000000000003e-28	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0944565	0.00854954	2.893269e-28	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15864906	chr14:103406384	14	103406384	CDC42BPB	Island	0.02435	0.00187	3.5000000000000004e-28	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0903751	0.00822278	5.4406e-28	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0895992	0.00822336	1.540713e-27	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg16283158	chr14:103433189	14	103433189	CDC42BPB	South shelf	-0.02766	0.00217	2.3e-27	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0918981	0.00857154	1.0156189999999999e-26	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0879605	0.00822457	1.3483779999999998e-26	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10258505	chr14:103469439	14	103469439	CDC42BPB	Open sea	-0.02346	0.00188	1.6e-26	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0878186	0.00822467	1.6239849999999998e-26	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0875107	0.0082249	2.4285649999999997e-26	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0866229	0.00822554	7.690159e-26	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-	-	9.78e-26	-	23526956_clear_cell_renal_carcinoma
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	0.002	None	1.4e-25	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	2	0.195	1.5999999999999998e-25	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	0.01561	0.00129	1.5999999999999998e-25	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	-0.03724	0.00307	1.7e-25	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0859331	0.00822603	1.867641e-25	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0856968	0.0082262	2.52713e-25	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0855901	0.00822627	2.895922e-25	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.085224	0.00822653	4.616466e-25	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0842798	0.0082272	1.5224559999999999e-24	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.084148	0.00822729	1.7964800000000003e-24	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01100318	chr14:103469348	14	103469348	CDC42BPB	Open sea	-0.0232	0.00198	2.2999999999999997e-24	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0839104	0.00822745	2.4193600000000002e-24	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0839023	0.00822746	2.444277e-24	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0838549	0.00822749	2.593391e-24	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.0011	None	3.1999999999999998e-24	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0831687	0.00822797	6.095564e-24	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0830629	0.00822804	6.949420000000001e-24	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.78746883	0.0783	8.61e-24	-	25888029_ageing
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0826354	0.00822833	1.1786560000000002e-23	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.04	0.00394	1.5e-23	None	Robert-F-Hillary_Incident_COPD_Basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.32748	0.0327259	1.649298e-23	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18211157	chr14:103469613	14	103469613	CDC42BPB	Open sea	0.0014	None	1.9e-23	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Nones K	-	24500968	2014-05-09	Pancreatic ductal adenocarcinoma	EFO_0002517	-	Table S4	DNA methylation	Pancreatic ductal adenocarcinoma	-	Beta values	-	Illumina HumanMethylation450	Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata	-	196	1	-	Missing	None	cg02855302	chr14:103453791	14	103453791	CDC42BPB	Open sea	-	-	2.3499999999999997e-23	-	24500968_pancreatic_ductal_adenocarcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0861114	0.00863452	2.3767620000000002e-23	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.081914	0.00822882	2.856391e-23	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	0.0816286	0.00822902	4.045399e-23	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18327049	chr14:103470338	14	103470338	CDC42BPB	Open sea	0.00064	None	4.1e-23	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0844067	0.00854207	5.919009e-23	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0812245	0.00822929	6.608222e-23	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0149	0.0015	9.000000000000001e-23	-	27651444_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0808794	0.00822952	1.002941e-22	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	0.0803943	0.00822985	1.797457e-22	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0842376	0.00862816	1.8976450000000001e-22	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13231302	chr14:103467798	14	103467798	CDC42BPB	Open sea	0.00051	None	2.4e-22	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0800625	0.00823007	2.673554e-22	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.079809	0.00823023	3.617217e-22	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-	-	4.46e-22	-	23526956_clear_cell_renal_carcinoma
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.224502	0.0232593	5.470532e-22	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.079126	0.00823068	8.129027e-22	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0829147	0.00864614	1.0220399999999999e-21	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0784432	0.00823113	1.81367e-21	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0783958	0.00823116	1.917087e-21	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0783469	0.00823119	2.029814e-21	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26403748	chr14:103406333	14	103406333	CDC42BPB	Island	0.02541	0.00237	2.4e-21	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0778348	0.00823152	3.6860899999999996e-21	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.00167421	0.00017416	4.8700000000000005e-21	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0775919	0.00823168	4.885519e-21	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	0.00065	None	6.6e-21	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0789049	0.00841113	7.475488e-21	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.077094	0.008232	8.678465e-21	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.0770826	0.00823201	8.792563999999999e-21	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0770732	0.00823201	8.888237e-21	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	-0.04	0.00334	9.9e-21	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.081159	0.0086791	9.908021e-21	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.0769323	0.0082321	1.045081e-20	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0799401	0.00856895	1.2186509999999999e-20	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0766923	0.00823225	1.37598e-20	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0766079	0.00823231	1.515358e-20	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.076033	0.00823267	2.916524e-20	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	3.6	0.39	3.3e-20	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14533120	chr14:103447664	14	103447664	CDC42BPB	Open sea	0.0024	None	3.9e-20	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-	-	4.07e-20	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0755475	0.00823298	5.0510409999999997e-20	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0752799	0.00823314	6.825866999999999e-20	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0775351	0.00848281	7.033826e-20	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0751199	0.00823324	8.168905e-20	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.07789	0.00858613	1.3194729999999998e-19	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0743376	0.00823373	1.9549059999999999e-19	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.051	0.00562	2.7e-19	None	Robert-F-Hillary_Incident_COPD_Basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16561957	chr14:103430940	14	103430940	CDC42BPB	South shore	0.0039	None	2.7e-19	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0739986	0.00823393	2.845388e-19	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0738054	0.00823405	3.521186e-19	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0775387	0.00866038	3.8596549999999995e-19	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	-0.48489	0.0542	3.95e-19	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0736396	0.00823415	4.2264239999999995e-19	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0771405	0.00862648	4.260411e-19	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0735906	0.00823418	4.460030000000001e-19	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	-0.39018	0.0438	4.95e-19	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0734582	0.00823426	5.15749e-19	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0733327	0.00823434	5.918245e-19	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0731715	0.00823444	7.059001999999999e-19	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10124651	chr14:103523278	14	103523278	CDC42BPB	Island	0.01096	0.00111	7.8e-19	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0729464	0.00823457	9.023881999999999e-19	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0081	9e-04	1e-18	-	27651444_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0725434	0.00823482	1.397912e-18	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0747926	0.00849827	1.506477e-18	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3580498 (gene symbol: CDC42BPB)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3580498 (gene symbol: CDC42BPB)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	None	None	1.9e-18	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3580498__gene_symbol__cdc42bpb__meta-analysis
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.91863304	0.1049	1.95e-18	-	25888029_ageing
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21937244	chr14:103406412	14	103406412	CDC42BPB	Island	0.0018	None	2e-18	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08236045	chr14:103449947	14	103449947	CDC42BPB	Open sea	0.00033	None	2.1e-18	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	2.5	0.289	2.3e-18	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0718946	0.00823521	2.814237e-18	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0046	None	3.7e-18	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.01074	0.00125	6.6e-18	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.00129628	0.00014777	6.82e-18	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04569190	chr14:103422560	14	103422560	CDC42BPB	Open sea	0.00076	None	6.9e-18	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0709342	0.00823577	7.838203e-18	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0709138	0.00823579	8.009901e-18	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.415349	0.0482959	8.601350000000001e-18	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0704301	0.00823607	1.3347010000000001e-17	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.0703888	0.00823609	1.393903e-17	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0697344	0.00823647	2.7652130000000002e-17	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0694197	0.00823665	3.835491e-17	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0728874	0.00868091	5.0261320000000005e-17	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0711983	0.00848513	5.2590380000000007e-17	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0691023	0.00823683	5.3268160000000005e-17	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0688838	0.00823696	6.67246e-17	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0715681	0.00857772	7.851119e-17	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0687059	0.00823706	8.012018000000001e-17	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.068605	0.00823712	8.885694000000001e-17	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	-0.02207	0.00242	9.1e-17	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0678654	0.00823754	1.889158e-16	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13148496	chr14:103430618	14	103430618	CDC42BPB	Island	-0.00056	0.000068	2.2e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.016	0.0019	2.2e-16	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0674847	0.00823775	2.776941e-16	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0701054	0.00855843	2.794062e-16	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0674774	0.00823775	2.797482e-16	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13148496	chr14:103430618	14	103430618	CDC42BPB	Island	0.01101	0.00123	2.8e-16	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12932547	chr14:103427159	14	103427159	CDC42BPB	North shelf	-0.01675	0.00188	3.8e-16	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18733798	chr14:103469879	14	103469879	CDC42BPB	Open sea	0.0064	None	4.3e-16	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0793123	0.0097559	4.646268e-16	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0668465	0.0082381	5.271084e-16	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.00010469	1.3e-05	6.66e-16	-	27843151_alcohol_consumption_per_day_african_ancestry
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07167192	chr14:103524430	14	103524430	CDC42BPB	Island	0.00481	0.00055	6.7e-16	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10291119	chr14:103403760	14	103403760	CDC42BPB	North shelf	-0.00046	0.000056	6.7e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0664056	0.00823835	8.1777e-16	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0693128	0.00862868	0.00000000000000102454	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.398096	0.0496134	0.000000000000001088823	None	39706196_Hannah-M.-Smith_bmi_discovery
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.00558	0.0007	0.0000000000000011	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.011	0.0013	0.0000000000000011	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02995680	chr14:103430766	14	103430766	CDC42BPB	Island	0.0045	None	0.0000000000000014	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0695636	0.00870554	0.000000000000001440926	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0690924	0.00865587	0.000000000000001544161	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0655472	0.00823882	0.00000000000000190768	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.068643	0.00863321	0.000000000000001983846	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0650083	0.00823911	0.000000000000003228881	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.0018	None	0.0000000000000038	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0679418	0.00864698	0.000000000000004197045	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0646574	0.00823929	0.000000000000004538289	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	2.5	0.313	0.0000000000000047	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0646114	0.00823932	0.00000000000000474458	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.0644811	0.00823939	0.000000000000005380758	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0644706	0.00823939	0.000000000000005435693	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg24755931	chr14:103407195	14	103407195	CDC42BPB	South shore	-0.74676445	0.0956	0.0000000000000055	-	25888029_ageing
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.011	0.0014	0.0000000000000064	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0640599	0.00823961	0.000000000000008068583	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0053	0.00068	0.0000000000000082	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14003974	chr14:103497991	14	103497991	CDC42BPB	Open sea	-0.0006	0.000077	0.0000000000000084	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0639997	0.00823964	0.000000000000008547355	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0639669	0.00823966	0.000000000000008819914	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0639083	0.00823969	0.000000000000009328931	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	0.0638788	0.00823971	0.000000000000009596081	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0638424	0.00823973	0.000000000000009935282	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	1.9	0.243	0.00000000000001	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0638352	0.00823973	0.00000000000001000405	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0637954	0.00823975	0.00000000000001039216	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0635699	0.00823987	0.0000000000000128832	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0635654	0.00823987	0.0000000000000129384	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11741956	chr14:103438353	14	103438353	CDC42BPB	Open sea	0.0028	None	0.000000000000013	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0658278	0.00854662	0.00000000000001422788	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0660709	0.00859763	0.00000000000001629598	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.179413	0.0233537	0.00000000000001644075	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0632072	0.00824006	0.00000000000001817634	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0630866	0.00824012	0.00000000000002037146	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.063072	0.00824013	0.00000000000002065324	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.065506	0.00856232	0.00000000000002126318	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0653897	0.00857501	0.00000000000002577563	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0651896	0.00856566	0.00000000000002894609	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	0.0624942	0.00824043	0.00000000000003555419	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0637831	0.00841159	0.00000000000003585312	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg04569190	chr14:103422560	14	103422560	CDC42BPB	Open sea	-0.28987	0.0383	0.0000000000000369	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.062433	0.00824046	0.00000000000003764767	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.00115206	0.00015037	0.0000000000000416	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.00585	0.00078	0.000000000000043	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14448215	chr14:103465967	14	103465967	CDC42BPB	Open sea	0.0011	None	0.000000000000048	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	2.7	0.355	0.000000000000049	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0620983	0.00824064	0.00000000000005143819	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0620223	0.00824068	0.00000000000005520578	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14448215	chr14:103465967	14	103465967	CDC42BPB	Open sea	0.0037	None	0.000000000000059	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0619391	0.00824072	0.0000000000000596383	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	2.4	0.317	0.000000000000065	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0618268	0.00824078	0.00000000000006618011	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0623412	0.0083102	0.00000000000006657215	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0618167	0.00824078	0.00000000000006679894	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16058220	chr14:103490442	14	103490442	CDC42BPB	Open sea	0.0614108	0.00824099	0.0000000000000971553	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0612538	0.00824107	0.0000000000001122361	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0612513	0.00824107	0.0000000000001124965	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0632718	0.00851738	0.0000000000001158433	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.41391	0.0557272	0.0000000000001158781	None	39706196_Hannah-M.-Smith_bmi_discovery
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg13231302	chr14:103467798	14	103467798	CDC42BPB	Open sea	-0.34556	0.0466	0.000000000000118	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0610632	0.00824116	0.0000000000001336483	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.060962	0.00824122	0.0000000000001466107	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	0.0606055	0.00824139	0.0000000000002028541	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0630613	0.008578	0.0000000000002063317	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0605807	0.00824141	0.0000000000002074762	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0605405	0.00824143	0.000000000000215173	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	0.0605159	0.00824144	0.0000000000002200342	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.317555	0.0433232	0.0000000000002404838	None	39706196_Hannah-M.-Smith_bmi_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.240677	0.0328704	0.0000000000002550709	None	39706196_Hannah-M.-Smith_body_fat_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.384807	0.0526032	0.0000000000002680767	None	39706196_Hannah-M.-Smith_bmi_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.363755	0.0497426	0.0000000000002731853	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0602107	0.00824159	0.0000000000002900192	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18358952	chr14:103468050	14	103468050	CDC42BPB	Open sea	-0.00046	0.000063	0.0000000000003	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0601377	0.00824163	0.0000000000003097418	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0601374	0.00824163	0.0000000000003098229	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0601321	0.00824163	0.0000000000003113234	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0601008	0.00824165	0.0000000000003202081	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0600532	0.00824167	0.0000000000003342298	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10258505	chr14:103469439	14	103469439	CDC42BPB	Open sea	0.0600123	0.00824169	0.0000000000003467776	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Ligthart S	CHARGE	27955697	2016-12-12	C-reactive protein	EFO_0004458	Discovery	Table S3	DNA methylation	C-reactive protein	Age, sex, smoking, body mass index, cell counts and technical covariates	Beta values	mg/l	Illumina HumanMethylation450	Whole blood	C-reactive protein levels were log-transformed	8863	9	65	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0047	0.000646	0.000000000000359	-	27955697_creactive_protein_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10239600	chr14:103411866	14	103411866	CDC42BPB	Open sea	-0.00025	0.000034	0.00000000000036	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0598562	0.00824177	0.000000000000398993	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0626853	0.0086529	0.000000000000455911	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.072	0.00996	0.00000000000047	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0595467	0.00824192	0.0000000000005263624	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.413221	0.0573503	0.0000000000006034437	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0017	0.00024	0.00000000000063	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0592422	0.00824207	0.0000000000006903258	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0590964	0.00824214	0.0000000000007856574	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16209303	chr14:103405847	14	103405847	CDC42BPB	North shore	-0.00084	0.00012	0.00000000000079	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0603275	0.00841855	0.0000000000008089203	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0589988	0.00824219	0.000000000000856562	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0687227	0.00962583	0.0000000000009813622	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0588378	0.00824227	0.0000000000009875164	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0588242	0.00824227	0.0000000000009994608	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0587857	0.00824229	0.000000000001033964	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0587322	0.00824232	0.00000000000108386	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0587226	0.00824232	0.000000000001093093	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg02938407	chr14:103486904	14	103486904	CDC42BPB	Open sea	0.031	0.0038	0.0000000000011	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0587122	0.00824233	0.000000000001103107	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0587075	0.00824233	0.000000000001107757	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0621788	0.0087368	0.000000000001155147	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07167192	chr14:103524430	14	103524430	CDC42BPB	Island	0.0001	None	0.0000000000012	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.0675928	0.00952403	0.000000000001332667	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	ch.14.1795106F	chr14:103427065	14	103427065	CDC42BPB	North shelf	0.03902	0.0055	0.00000000000134	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0584804	0.00824244	0.000000000001352451	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14533120	chr14:103447664	14	103447664	CDC42BPB	Open sea	-0.0019	0.00027	0.0000000000014	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.058402	0.00824248	0.00000000000144862	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0583947	0.00824248	0.000000000001457981	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0583828	0.00824249	0.000000000001473264	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	2.4	0.339	0.0000000000015	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0583398	0.00824251	0.000000000001529691	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.06	0.00843	0.0000000000016	None	Robert-F-Hillary_Incident_COPD_Basic_model
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.00068	0.000094	0.0000000000017	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0605096	0.0085728	0.000000000001760859	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	0.0581672	0.00824259	0.000000000001778783	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0580512	0.00824265	0.000000000001968055	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0579441	0.0082427	0.000000000002160468	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.03195	0.0046	0.00000000000222	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0578429	0.00824275	0.000000000002358962	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0577773	0.00824278	0.000000000002496983	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04899282	chr14:103523516	14	103523516	CDC42BPB	Island	0.00066	0.000094	0.0000000000025	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16283158	chr14:103433189	14	103433189	CDC42BPB	South shelf	-0.00063	0.00009	0.0000000000025	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	2.2	0.307	0.0000000000025	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10124651	chr14:103523278	14	103523278	CDC42BPB	Island	0.00048	None	0.0000000000026	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0576886	0.00824282	0.000000000002696579	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0576652	0.00824283	0.000000000002751803	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0576402	0.00824284	0.000000000002811758	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18327049	chr14:103470338	14	103470338	CDC42BPB	Open sea	0.002	None	0.0000000000031	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19612114	chr14:103433138	14	103433138	CDC42BPB	South shelf	-0.01453	0.00195	0.0000000000031	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0598095	0.00857674	0.000000000003224698	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0574571	0.00824293	0.000000000003293712	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.387959	0.055866	0.000000000003934075	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.057206	0.00824305	0.000000000004088148	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.0571527	0.00824308	0.000000000004279619	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.057084	0.00824311	0.000000000004539198	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0570707	0.00824311	0.000000000004591	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.0657641	0.00951089	0.000000000004885581	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0569182	0.00824319	0.000000000005230914	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	3	0.43	0.0000000000056	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0567913	0.00824325	0.000000000005829548	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0566576	0.00824331	0.000000000006532959	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg26975587	chr14:103430286	14	103430286	CDC42BPB	North shore	-0.01585	0.0023	0.00000000000655	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0566545	0.00824331	0.000000000006550157	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.056633	0.00824332	0.000000000006670945	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.23	0.0336	0.0000000000067	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0565755	0.00824335	0.000000000007004851	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0565351	0.00824337	0.000000000007249253	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0564292	0.00824342	0.000000000007930858	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	0.0563915	0.00824343	0.000000000008187836	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0591347	0.00864672	0.000000000008291408	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Ligthart S	CHARGE	27955697	2016-12-12	C-reactive protein	EFO_0004458	Discovery	Table S3	DNA methylation	C-reactive protein	Age, sex, smoking, body mass index, cell counts and technical covariates	Beta values	mg/l	Illumina HumanMethylation450	Whole blood	C-reactive protein levels were log-transformed	8863	9	65	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0041	6e-04	0.0000000000084	-	27955697_creactive_protein_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0562747	0.00824349	0.000000000009038415	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0562031	0.00824352	0.000000000009601798	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0586302	0.00861884	0.00000000001067526	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0585834	0.00862698	0.00000000001158642	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0558834	0.00824367	0.00000000001256777	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.05586	0.00824368	0.00000000001281663	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0584675	0.00863603	0.00000000001335065	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0046	0.0006	0.000000000014	None	33564054_Kashima-K_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0557424	0.00824373	0.00000000001414431	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Petersen A-K	KORA F4	24014485	2013-09-06	M33420_gamma-tocopherol	EFO_0004727, EFO_0004725	snps as covariates model	Table S4	M33420_gamma-tocopherol	DNA methylation	Age, sex, body mass index, cell composition (reference based), genotype	None	Beta Values	Illumina HumanMethylation450	Whole blood	used three nearby snps as covariates	1760	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.74	0.085	0.000000000015	None	24014485_Petersen-A-K_m33420_gamma-tocopherol_snps_as_covariates_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0577978	0.0085661	0.0000000000156301	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.0554935	0.00824385	0.00000000001741486	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.33357	0.0496021	0.00000000001811926	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0572224	0.00850981	0.00000000001829894	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.057701	0.00858753	0.00000000001895187	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0576211	0.00857801	0.00000000001919301	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.057953	0.00862743	0.00000000001919374	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0578861	0.00861971	0.00000000001942436	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.0553349	0.00824392	0.00000000001987406	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.057152	0.00853633	0.00000000002232897	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	9.78e-05	1.46e-05	0.000000000024	-	27843151_alcohol_consumption_per_day_african_ancestry
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27028800	chr14:103411330	14	103411330	CDC42BPB	Open sea	0.0548938	0.00824412	0.00000000002863943	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0548155	0.00824416	0.00000000003054923	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Petersen A-K	KORA F4	24014485	2013-09-06	M15753_hippurate	EFO_0004727, EFO_0004725	snps as covariates model	Table S4	M15753_hippurate	DNA methylation	Age, sex, body mass index, cell composition (reference based), genotype	None	Beta Values	Illumina HumanMethylation450	Whole blood	used three nearby snps as covariates	1760	1	Adults	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.96	0.21	0.000000000033	None	24014485_Petersen-A-K_m15753_hippurate_snps_as_covariates_model
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg18733798	chr14:103469879	14	103469879	CDC42BPB	Open sea	-0.64316862	0.097	0.0000000000335	-	25888029_ageing
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	0.0546405	0.00824424	0.00000000003528079	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0703738	0.0106222	0.00000000003589664	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0545791	0.00824426	0.00000000003710537	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.00084	0.00013	0.000000000042	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13231302	chr14:103467798	14	103467798	CDC42BPB	Open sea	0.0016	None	0.000000000042	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-	-	0.0000000000444	-	26500701_sex_kora_f4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.283385	0.0430274	0.00000000004643509	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0943407	0.0143234	0.00000000004657459	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04754454	chr14:103475666	14	103475666	CDC42BPB	Open sea	0.01665	0.00239	0.000000000048	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.215634	0.0328052	0.00000000005066352	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0541086	0.00824448	0.00000000005449958	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.054045	0.0082445	0.00000000005739331	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0538986	0.00824457	0.00000000006463703	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Petersen A-K	KORA F4	24014485	2013-09-06	M33420_gamma-tocopherol	EFO_0004727, EFO_0004725	no snps model	Table S2	M33420_gamma-tocopherol	DNA methylation	Age, sex, body mass index, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1760	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.72	0.084	0.000000000068	None	24014485_Petersen-A-K_m33420_gamma-tocopherol_no_snps_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0565763	0.00866713	0.00000000006899014	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	-0.2074	0.0318	0.0000000000706	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0537615	0.00824463	0.00000000007222443	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	1.4	0.213	0.000000000074	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	-0.0012	0.00018	0.000000000079	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0536482	0.00824468	0.00000000007914925	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0536388	0.00824469	0.00000000007974936	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.02842	0.00413	0.00000000008	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0536235	0.00824469	0.00000000008074294	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0542668	0.00835483	0.00000000008556424	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0535321	0.00824473	0.00000000008691725	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Stroke	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Stroke	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18023	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.025	0.00382	0.000000000089	None	Robert-F-Hillary_Incident_Stroke_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0534822	0.00824475	0.0000000000904804	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0925689	0.0143002	0.00000000009895402	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Petersen A-K	KORA F4	24014485	2013-09-06	M33420_gamma-tocopherol	EFO_0004727, EFO_0004725	snps as covariates model	Table S4	M33420_gamma-tocopherol	DNA methylation	Age, sex, body mass index, cell composition (reference based), genotype	None	Beta Values	Illumina HumanMethylation450	Whole blood	used three nearby snps as covariates	1760	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.79	0.106	0.000000000099	None	24014485_Petersen-A-K_m33420_gamma-tocopherol_snps_as_covariates_model
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0058	9e-04	0.0000000001	-	27651444_smoking_current_vs_never_smoking
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13148496	chr14:103430618	14	103430618	CDC42BPB	Island	0.0005	None	0.0000000001	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18931727	chr14:103512157	14	103512157	CDC42BPB	Open sea	0.0533445	0.00824482	0.000000000101069	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	0.0533227	0.00824483	0.0000000001028532	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0533038	0.00824483	0.0000000001044205	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0531663	0.00824489	0.0000000001165767	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0531575	0.0082449	0.000000000117406	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0531252	0.00824491	0.0000000001204727	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Petersen A-K	KORA F4	24014485	2013-09-06	M15753_hippurate	EFO_0004727, EFO_0004725	no snps model	Table S2	M15753_hippurate	DNA methylation	Age, sex, body mass index, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1760	1	Adults	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.95	0.21	0.00000000013	None	24014485_Petersen-A-K_m15753_hippurate_no_snps_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.0598667	0.00931504	0.000000000134269	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	0.0528852	0.00824502	0.0000000001458973	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13148496	chr14:103430618	14	103430618	CDC42BPB	Island	0.0017	None	0.00000000015	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0528421	0.00824504	0.0000000001509856	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0528076	0.00824505	0.0000000001551866	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0527987	0.00824506	0.0000000001562907	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0527902	0.00824506	0.0000000001573548	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0694847	0.0108688	0.0000000001675525	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0526933	0.0082451	0.00000000016993	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0526806	0.00824511	0.0000000001716523	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09985481	chr14:103411899	14	103411899	CDC42BPB	Open sea	-0.00046	0.000072	0.00000000018	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.01	0.0016	0.00000000018	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0526015	0.00824514	0.0000000001827608	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Petersen A-K	KORA F4	24014485	2013-09-06	M33420_gamma-tocopherol	EFO_0004727, EFO_0004725	no snps model	Table S2	M33420_gamma-tocopherol	DNA methylation	Age, sex, body mass index, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1760	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.79	0.104	0.00000000019	None	24014485_Petersen-A-K_m33420_gamma-tocopherol_no_snps_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0525492	0.00824516	0.0000000001904916	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.052478	0.00824519	0.0000000002015118	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0524735	0.0082452	0.0000000002022375	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.055058	0.00865323	0.0000000002041156	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	0.0013	None	0.00000000021	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.052389	0.00824523	0.0000000002161769	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10508852	chr14:103404960	14	103404960	CDC42BPB	North shore	0.0014	None	0.00000000022	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0523541	0.00824525	0.0000000002222103	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0523471	0.00824525	0.0000000002234384	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.052323	0.00824526	0.0000000002277401	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0523097	0.00824527	0.0000000002301307	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	5.7e-05	9e-06	0.000000000239	-	27843151_alcohol_consumption_per_day_african_ancestry
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.275143	0.0434394	0.0000000002448515	None	39706196_Hannah-M.-Smith_body_fat_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Lung Cancer	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Lung Cancer	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18364	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.013	0.00211	0.00000000025	None	Robert-F-Hillary_Incident_Lung_Cancer_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0520647	0.00824537	0.0000000002789977	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.052025	0.00824539	0.0000000002878219	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	0.0520216	0.00824539	0.0000000002885839	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.052005	0.0082454	0.0000000002923601	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.051995	0.0082454	0.000000000294658	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.146844	0.0233134	0.0000000003073994	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0519369	0.00824543	0.0000000003083631	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26669125	chr14:103432390	14	103432390	CDC42BPB	South shore	0.051923	0.00824543	0.0000000003117413	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.002	None	0.00000000032	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.052	0.00826	0.00000000032	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.051747	0.00824551	0.0000000003576717	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	0.0516846	0.00824554	0.0000000003754779	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.051595	0.00824557	0.0000000004026061	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	0.163122	0.0261017	0.0000000004214777	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.05146	0.00824563	0.0000000004470868	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	0.0031	None	0.00000000045	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	0.051406	0.00824565	0.0000000004661739	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0514051	0.00824566	0.0000000004664961	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.0512759	0.00824571	0.0000000005155638	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.051046	0.00824581	0.000000000615529	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.0510206	0.00824582	0.0000000006277085	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0509985	0.00824583	0.0000000006384684	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0509684	0.00824584	0.0000000006534044	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-	-	0.000000000672	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12932547	chr14:103427159	14	103427159	CDC42BPB	North shelf	0.0509204	0.00824586	0.0000000006779425	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.029	0.00464	0.00000000068	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	PRG3 protein levels (SeqId = 9015-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRG3 protein levels (SeqId = 9015-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteoglycan 3	774	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	-1.23	0.2	0.00000000069	None	Gadd-DA_prg3_protein_levels__seqid___9015-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0657923	0.0106635	0.000000000701427	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.0508673	0.00824588	0.0000000007061326	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0507803	0.00824592	0.0000000007548008	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0507608	0.00824593	0.0000000007661489	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0507477	0.00824593	0.0000000007738595	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0507215	0.00824594	0.0000000007895258	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.266294	0.0433093	0.0000000007985447	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19561503	chr14:103433986	14	103433986	CDC42BPB	South shelf	0.0025	None	0.00000000082	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0526484	0.00859545	0.0000000009291373	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Petersen A-K	KORA F4	24014485	2013-09-06	M35718_dihomo-linolenate_20:3n3_or_n6	EFO_0004727, EFO_0004725	no snps model	Table S2	M35718_dihomo-linolenate_20:3n3_or_n6	DNA methylation	Age, sex, body mass index, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1760	1	Adults	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.56	0.058	0.00000000096	None	24014485_Petersen-A-K_m35718_dihomo-linolenate_20_3n3_or_n6_no_snps_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0661036	0.0108031	0.000000000965858	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04754454	chr14:103475666	14	103475666	CDC42BPB	Open sea	-0.0011	0.00018	0.00000000098	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.055	0.00902	0.000000001	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.0503987	0.00824608	0.000000001009793	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0523689	0.00858295	0.000000001077242	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	2	0.326	0.0000000011	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.059	0.00972	0.0000000011	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0522084	0.00856753	0.000000001130531	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.256781	0.0421628	0.000000001150205	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-	-	0.00000000119	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.0501272	0.00824619	0.00000000124059	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0501222	0.00824619	0.000000001245311	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.063	0.0103	0.0000000013	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24755931	chr14:103407195	14	103407195	CDC42BPB	South shore	0.0011	None	0.0000000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.0500652	0.00824622	0.000000001300089	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0500499	0.00824622	0.000000001315243	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.050002	0.00824624	0.000000001363622	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0499958	0.00824625	0.000000001370087	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0499696	0.00824626	0.000000001397348	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Liver Cirrhosis	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Liver Cirrhosis	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18325	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0094	0.00154	0.0000000014	None	Robert-F-Hillary_Incident_Liver_Cirrhosis_Basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18358952	chr14:103468050	14	103468050	CDC42BPB	Open sea	0.00045	None	0.0000000014	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0512292	0.0084645	0.000000001463219	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21937244	chr14:103406412	14	103406412	CDC42BPB	Island	0.0498702	0.0082463	0.000000001505977	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0498083	0.00824632	0.000000001577814	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0626541	0.010381	0.000000001623389	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.0497641	0.00824634	0.000000001631053	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.0514126	0.00852778	0.000000001691051	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0515147	0.00855413	0.000000001761683	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.62326373	0.1036	0.00000000178	-	25888029_ageing
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0495559	0.00824643	0.000000001906431	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	2.4	0.404	0.000000002	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0903254	0.01508	0.000000002150861	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.131112	0.021924	0.000000002271343	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0492932	0.00824653	0.000000002319213	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0492896	0.00824654	0.000000002325457	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10124651	chr14:103523278	14	103523278	CDC42BPB	Island	0.125399	0.0209849	0.000000002336816	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0492865	0.0082504	0.000000002371156	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0491728	0.00824658	0.000000002536308	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0491546	0.00824659	0.000000002570808	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Rheumatoid Arthritis (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Rheumatoid Arthritis (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18055	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.073	0.0122	0.0000000026	None	Robert-F-Hillary_Prevalent_Rheumatoid_Arthritis_(Self-report)_Basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.088	0.0148	0.0000000027	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27028800	chr14:103411330	14	103411330	CDC42BPB	Open sea	-0.00069	0.00012	0.0000000027	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.0490798	0.00824662	0.000000002717402	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0490762	0.00824662	0.000000002724809	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	0.0490489	0.00824663	0.000000002780386	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08236045	chr14:103449947	14	103449947	CDC42BPB	Open sea	-0.00021	0.000036	0.000000003	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.0489438	0.00824668	0.00000000300512	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0512589	0.0086504	0.000000003181162	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0488445	0.00824672	0.000000003233868	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0487888	0.00824674	0.000000003369323	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0512158	0.00866432	0.00000000347348	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0503767	0.00852638	0.000000003532578	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg21164005	chr14:103410594	14	103410594	CDC42BPB	South shelf	1.452799	0.2461	0.00000000358	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0486829	0.00824678	0.000000003642663	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPPA protein levels (SeqId = 4148-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPPA protein levels (SeqId = 4148-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pappalysin-1	774	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	-1.17	0.199	0.0000000037	None	Gadd-DA_pappa_protein_levels__seqid___4148-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0486434	0.0082468	0.000000003749889	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0486221	0.00824681	0.000000003809034	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	0.0486137	0.00824681	0.000000003832688	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0486088	0.00824681	0.000000003846473	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0485307	0.00824684	0.000000004073341	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0485139	0.00824685	0.000000004123721	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0473726	0.00805731	0.000000004205487	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0484813	0.00824686	0.000000004223225	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0484377	0.00824688	0.000000004360218	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0886739	0.0151077	0.00000000446667	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18358952	chr14:103468050	14	103468050	CDC42BPB	Open sea	0.01039	0.00169	0.0000000045	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0483789	0.0082469	0.000000004551818	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	-0.0483271	0.00824692	0.000000004727405	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0483093	0.00824693	0.000000004789225	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.0483054	0.00824693	0.000000004802947	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0482679	0.00824695	0.00000000493636	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.014	0.0022	0.0000000051	None	33564054_Kashima-K_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.0482062	0.00824697	0.000000005163334	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Battram T	GEO	27886173	2020-09-15	Inflammatory bowel disease	EFO_0003767	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Inflammatory bowel disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	240	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0352	0.00578	0.0000000052	None	27886173_Battram-T_inflammatory_bowel_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	ch.14.1795106F	chr14:103427065	14	103427065	CDC42BPB	North shelf	-0.03962	0.00648	0.0000000052	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	-0.001	0.00018	0.0000000053	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0504399	0.00864611	0.000000005531483	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	0.00057	None	0.0000000057	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0502282	0.00861929	0.000000005747452	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.0480163	0.00824705	0.000000005927797	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.084807	0.014571	0.000000005998186	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	2.2	0.378	0.000000006	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0569287	0.00979243	0.000000006243548	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0487036	0.00839603	0.000000006736329	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0503018	0.00867366	0.000000006793685	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0531928	0.0091743	0.000000006848339	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16058220	chr14:103490442	14	103490442	CDC42BPB	Open sea	0.0478077	0.00824713	0.000000006894529	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0477862	0.00824714	0.000000007002566	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0671402	0.0116008	0.00000000728771	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0476918	0.00824718	0.000000007496404	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0476913	0.00824718	0.000000007498786	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg27028800	chr14:103411330	14	103411330	CDC42BPB	Open sea	-2.4	0.409	0.0000000075	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21937244	chr14:103406412	14	103406412	CDC42BPB	Island	0.0476828	0.00824718	0.000000007544822	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Dugue PA	Melbourne Collaborative Cohort Study	31552803	2019-09-25	Smoking	EFO_0006527, EFO_0004318	Current vs never smoking	Supplementary table 1	DNA methylation	Smoking	Sex, country of birth, age, alcohol consumption, cell composition (reference based), batch effects	M Values	None	Illumina HumanMethylation450	Whole blood	None	1851	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.12	0.0208	0.000000008	None	31552803_Dugue-PA_smoking_current_vs_never_smoking
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.038	0.00661	0.0000000081	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0475756	0.00824722	0.000000008150793	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg10291119	chr14:103403760	14	103403760	CDC42BPB	North shelf	0.22065	0.0383	0.00000000819	-	25650246_gestational_age
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg26403748	chr14:103406333	14	103406333	CDC42BPB	Island	-1.170005	0.203	0.00000000828	-	27105112_hiv_infection_discovery
Battram T	GEO	27886173	2020-09-15	Inflammatory bowel disease	EFO_0003767	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Inflammatory bowel disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	240	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.039	0.0065	0.0000000083	None	27886173_Battram-T_inflammatory_bowel_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0474873	0.00824726	0.000000008684759	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.047417	0.00824728	0.000000009133718	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0474078	0.00824729	0.000000009194076	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.045672	0.00795538	0.000000009596751	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0473471	0.00824731	0.0000000096031	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0473466	0.00824731	0.000000009606469	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.0473437	0.00824731	0.000000009626722	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0473362	0.00824732	0.00000000967804	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0610784	0.0106461	0.000000009817242	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0491004	0.00855913	0.000000009849533	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.148515	0.0259455	0.00000001057022	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.083055	0.014518	0.00000001080832	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Dugue PA	Melbourne Collaborative Cohort Study	31552803	2019-09-25	Smoking	EFO_0006527, EFO_0004318	Current vs never smoking	Supplementary table 1	DNA methylation	Smoking	Sex, country of birth, age, alcohol consumption, cell composition (reference based), batch effects	M Values	None	Illumina HumanMethylation450	Whole blood	None	1851	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.09	0.0157	0.000000011	None	31552803_Dugue-PA_smoking_current_vs_never_smoking
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06609295	chr14:103400081	14	103400081	CDC42BPB	South shelf	-0.00045	0.000079	0.000000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10124651	chr14:103523278	14	103523278	CDC42BPB	Island	0.120211	0.0210348	0.00000001116139	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0492604	0.00862723	0.00000001152541	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0470748	0.00824742	0.00000001166433	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	0.0470391	0.00824743	0.0000000119646	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.00092	None	0.000000012	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0475422	0.00835592	0.00000001297334	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0467588	0.00824754	0.00000001459788	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.358369	0.0633	0.0000000146	-	27105112_hiv_infection_neutrophils
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.237321	0.0418962	0.00000001496875	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	0.148058	0.0261668	0.00000001553383	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.046653	0.00824758	0.00000001573183	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.00075303	0.00013216	0.0000000158	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Jovanova OS	CHARGE and ARIC	29998287	2018-09-01	Depressive symptoms	EFO_0007006, MONDO_0002050	Meta-analysis	Table 2	DNA methylation	Depressive symptoms	Age, sex, smoking, batch effects, cell composition (reference based), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	11256	11	Adults	Both	European, African	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	None	None	0.000000016	None	29998287_Jovanova-OS_depressive_symptoms_meta-analysis
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-	-	0.0000000162	-	26857698_primary_sjogrens_syndrome_whole_blood
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg19582115	chr14:103436037	14	103436037	CDC42BPB	Open sea	-0.242438	0.043	0.0000000166	-	27105112_hiv_infection_neutrophils
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.0540764	0.00957926	0.00000001680954	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10508852	chr14:103404960	14	103404960	CDC42BPB	North shore	0.0045	None	0.000000017	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0464825	0.00824765	0.00000001774053	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.056	0.0091	0.000000018	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0655136	0.0116302	0.00000001802947	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0464491	0.00824766	0.00000001816258	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0482229	0.00856551	0.00000001836304	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0463561	0.0082477	0.00000001938834	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16058220	chr14:103490442	14	103490442	CDC42BPB	Open sea	0.0476342	0.00847647	0.00000001949107	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0608764	0.0108351	0.00000001962223	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15988734	chr14:103411822	14	103411822	CDC42BPB	Open sea	0.00023	None	0.00000002	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0462775	0.00824773	0.00000002048641	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0609664	0.01087	0.00000002075408	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0488238	0.00870786	0.00000002097426	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.048399	0.00863391	0.0000000211165	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0462303	0.00824774	0.00000002117582	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0461596	0.00824777	0.00000002224867	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0461573	0.00824777	0.00000002228461	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0460515	0.00824781	0.0000000239932	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.039	0.0069	0.000000024	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0478948	0.00858136	0.000000024301	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0459827	0.00824784	0.00000002517242	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0459464	0.00824785	0.00000002581705	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0459454	0.00824785	0.0000000258342	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0576899	0.0103635	0.00000002642551	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg04987955	chr14:103438392	14	103438392	CDC42BPB	Open sea	-0.00906	0.0016	0.0000000268	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0478717	0.00860456	0.00000002690028	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0458865	0.00824787	0.00000002691424	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg27028800	chr14:103411330	14	103411330	CDC42BPB	Open sea	0.015	0.00242	0.000000027	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.04587	0.00824788	0.00000002722427	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.04578	0.00824791	0.00000002897989	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Christiansen C	TwinsUK, NSHD, NCDS1, NCDS2, BCS70	33593402	2021-02-16	Smoking	EFO_0004318, EFO_0006527	Current vs never smoking meta-analysis in European samples	Table S1	DNA methylation	Smoking	Sex, cell composition (reference based), body mass index, batch effects, relatedness	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	912	5	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	None	None	0.000000029	None	33593402_Christiansen-C_smoking_current_vs_never_smoking_meta-analysis_in_european_samples
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.314749	0.0567166	0.00000002905316	None	39706196_Hannah-M.-Smith_glucose_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0633739	0.0114229	0.00000002939964	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0456698	0.00824796	0.00000003128015	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	-0.0149	0.00258	0.000000032	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0455303	0.00824801	0.00000003444429	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0455291	0.00824801	0.00000003447399	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0455264	0.00824801	0.0000000345373	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0454746	0.00824803	0.00000003579374	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.210106	0.0381169	0.00000003595512	None	39706196_Hannah-M.-Smith_bmi_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Rheumatoid Arthritis (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Rheumatoid Arthritis (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18055	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.047	0.0085	0.000000036	None	Robert-F-Hillary_Prevalent_Rheumatoid_Arthritis_(Self-report)_Basic_model
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-	-	0.0000000363	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.045435	0.00824804	0.00000003678225	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0454319	0.00824805	0.00000003686068	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0572937	0.0104019	0.00000003690873	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0453321	0.00824808	0.0000000394819	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.012	0.0022	0.000000041	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.0452523	0.00824811	0.00000004170405	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	0.0452225	0.00824812	0.0000000425658	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.045195	0.00824813	0.0000000433756	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.045183	0.00824814	0.00000004373396	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.00044625	8.09e-05	0.0000000438	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0451803	0.00824814	0.00000004381537	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0508109	0.00927926	0.00000004428449	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0451539	0.00824815	0.00000004461418	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0594662	0.0108642	0.00000004482404	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0451417	0.00824815	0.00000004498645	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0474459	0.00867484	0.00000004590193	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.208209	0.0380878	0.00000004652014	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0450854	0.00824818	0.00000004675346	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0473681	0.00867095	0.00000004761705	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.13693	0.0251	0.0000000478	-	25650246_gestational_age
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-	-	0.0000000485	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0450279	0.0082482	0.00000004862732	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	-0.0067	0.0012	0.000000049	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0566812	0.0103995	0.00000005107088	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.0449522	0.00824823	0.00000005120564	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0449387	0.00824823	0.00000005167729	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0449387	0.00824823	0.00000005167884	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.044924	0.00824824	0.00000005219827	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0464011	0.00852496	0.00000005324062	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-	-	0.0000000533	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0520162	0.00956189	0.00000005414944	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0067	0.0012	0.000000055	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.0518587	0.00954099	0.00000005555952	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.0459527	0.00845773	0.00000005623174	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.044804	0.00824828	0.00000005663896	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0447849	0.00824829	0.00000005737933	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16334456	chr14:103436635	14	103436635	CDC42BPB	Open sea	0.0447804	0.00824829	0.00000005755507	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0467809	0.00862529	0.00000005930788	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg19589358	chr14:103410516	14	103410516	CDC42BPB	South shelf	-0.231416	0.0426731	0.00000005935312	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	-0.044711	0.00824831	0.00000006032855	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-	-	0.0000000624	-	26500701_sex_kora_f4
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.188599	0.0349	0.0000000626	-	27105112_hiv_infection_neutrophils
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.177239	0.0327578	0.00000006361209	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Ligthart S	CHARGE	27955697	2016-12-12	C-reactive protein	EFO_0004458	Discovery	Table S3	DNA methylation	C-reactive protein	Age, sex, smoking, body mass index, cell counts and technical covariates	Beta values	mg/l	Illumina HumanMethylation450	Whole blood	C-reactive protein levels were log-transformed	8863	9	65	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0019	0.000351	0.0000000645	-	27955697_creactive_protein_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21937244	chr14:103406412	14	103406412	CDC42BPB	Island	-0.0012	0.00021	0.000000065	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.044535	0.00824838	0.00000006796549	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0445114	0.00824839	0.00000006905835	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0457042	0.00847152	0.00000006957154	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0444986	0.00824839	0.00000006965826	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0786938	0.0145922	0.00000007041695	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0444543	0.00824841	0.00000007176941	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0444541	0.00824841	0.00000007178114	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0584128	0.0108417	0.00000007243933	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0444306	0.00824842	0.00000007292871	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0444092	0.00824843	0.00000007398547	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0460973	0.0085635	0.00000007438498	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0443931	0.00824843	0.00000007479149	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19582115	chr14:103436037	14	103436037	CDC42BPB	Open sea	-0.00073	0.00014	0.000000077	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0986606	0.0183691	0.00000007948864	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0573663	0.0106847	0.00000008038523	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0442414	0.00824849	0.00000008282518	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0442385	0.00824849	0.00000008298987	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Christiansen C	TwinsUK, NSHD, NCDS1, NCDS2, BCS70	33593402	2021-02-16	Smoking	EFO_0004318, EFO_0006527	Current vs never smoking meta-analysis in European samples	Table S1	DNA methylation	Smoking	Sex, cell composition (reference based), body mass index, batch effects, relatedness	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	912	5	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	None	None	0.000000083	None	33593402_Christiansen-C_smoking_current_vs_never_smoking_meta-analysis_in_european_samples
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.041	0.00765	0.000000083	None	Robert-F-Hillary_Incident_COPD_Basic_model
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	2.2	0.409	0.000000084	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0441949	0.0082485	0.00000008545362	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0572191	0.0106807	0.00000008576961	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0441281	0.00824853	0.00000008936893	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0512414	0.00957875	0.00000008952711	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0446807	0.00835488	0.0000000903373	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10087771	chr14:103399429	14	103399429	CDC42BPB	South shelf	0.044092	0.00824854	0.0000000915535	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0440805	0.00824855	0.0000000922609	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16058220	chr14:103490442	14	103490442	CDC42BPB	Open sea	0.0449485	0.00841565	0.00000009378485	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0440346	0.00824856	0.00000009513512	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0439975	0.00824858	0.00000009752791	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.0439841	0.00824858	0.00000009840241	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05734220	chr14:103524410	14	103524410	CDC42BPB	Island	0.00049	0.000093	0.000000099	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0439444	0.0082486	0.0000001010459	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0439328	0.0082486	0.0000001018304	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	0.0439251	0.0082486	0.0000001023517	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0439154	0.00824861	0.0000001030205	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.0495906	0.00931597	0.00000010347	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0760112	0.0142904	0.0000001058534	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0438659	0.00824862	0.0000001064704	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.0530088	0.00997422	0.0000001084684	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	0.0438195	0.00824864	0.0000001098114	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	-0.0026	5e-04	0.00000011	-	27651444_smoking_current_vs_never_smoking
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	-0.00256	0.00048	0.00000011	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.059	0.0111	0.00000011	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08236045	chr14:103449947	14	103449947	CDC42BPB	Open sea	0.0012	None	0.00000011	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.008	0.0015	0.00000011	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.054	0.01022	0.00000011	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0438142	0.00824864	0.0000001102004	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.0438096	0.00824864	0.0000001105363	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.045783	0.00862901	0.0000001138657	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0437451	0.00824867	0.0000001153819	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0437438	0.00824867	0.0000001154851	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.0437368	0.00824867	0.0000001160174	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0437184	0.00824868	0.0000001174447	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0437166	0.00824868	0.0000001175885	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19129605	chr14:103428549	14	103428549	CDC42BPB	North shore	0.0436994	0.00824868	0.0000001189343	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-	-	0.000000119	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	0.043688	0.00824869	0.0000001198381	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0436668	0.0082487	0.0000001215389	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0764054	0.0144401	0.0000001232636	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.283909	0.0537257	0.0000001275772	None	39706196_Hannah-M.-Smith_glucose_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.0435764	0.00824873	0.0000001290377	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0435315	0.00824874	0.000000132933	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0434803	0.00824876	0.0000001375128	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0450657	0.00855293	0.0000001390821	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_3
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.0076	0.0014	0.00000014	-	27651444_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	-0.043355	0.00824881	0.0000001493587	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0702812	0.0133969	0.0000001575232	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0432723	0.00824884	0.0000001577108	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.043259	0.00824884	0.0000001590964	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.045156	0.00861541	0.00000016166	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0432092	0.00824886	0.0000001643875	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0459854	0.00878388	0.0000001670838	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Stroke	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Stroke	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18023	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.028	0.00543	0.00000017	None	Robert-F-Hillary_Incident_Stroke_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0552555	0.0105633	0.0000001709995	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.225667	0.043236	0.0000001815497	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0430308	0.00824892	0.0000001847785	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0447845	0.00860463	0.0000001969325	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.042924	0.00824896	0.0000001981375	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.114231	0.0219797	0.0000002047263	None	39706196_Hannah-M.-Smith_body_fat_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.168101	0.0323551	0.0000002063947	None	39706196_Hannah-M.-Smith_glucose_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0447453	0.00861192	0.000000206637	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0474784	0.00914143	0.0000002088434	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18327049	chr14:103470338	14	103470338	CDC42BPB	Open sea	0.00571	0.00106	0.00000021	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0708597	0.0136514	0.0000002123635	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0428063	0.008249	0.000000213942	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0427948	0.00824901	0.0000002155461	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0427692	0.00824902	0.0000002191708	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	1.1	0.221	0.00000022	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0427606	0.00824902	0.0000002203928	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0450617	0.00869453	0.0000002215312	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg16561957	chr14:103430940	14	103430940	CDC42BPB	South shore	0.00655	0.00122	0.00000023	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0426582	0.00824906	0.0000002355485	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0426544	0.00824906	0.0000002361339	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	1.213715	0.2349	0.000000237	-	27105112_hiv_infection_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01100318	chr14:103469348	14	103469348	CDC42BPB	Open sea	0.241226	0.0466626	0.0000002372343	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0426338	0.00824906	0.0000002393074	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Lung Cancer	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Lung Cancer	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18364	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.016	0.00301	0.00000024	None	Robert-F-Hillary_Incident_Lung_Cancer_Basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	0.185712	0.0360227	0.000000255846	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0439231	0.00851937	0.0000002560162	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	0.0425176	0.00824911	0.0000002580222	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.287208	0.0557298	0.0000002583559	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	0.0424953	0.00824911	0.000000261757	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0436907	0.00849018	0.0000002695016	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.189455	0.0368373	0.0000002733109	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0559877	0.0108933	0.0000002787876	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02995680	chr14:103430766	14	103430766	CDC42BPB	Island	0.0423928	0.00824915	0.0000002796719	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.0423754	0.00824916	0.0000002828269	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0423645	0.00824916	0.0000002848266	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Park J	Korean Exposome Study	33515580	2021-01-28	prenatal lead exposure	CHEBI_25016	Meta-analysis in males only	None	DNA methylation	prenatal lead exposure	Sex, maternal pre-pregnancy BMI, maternal current smoking, cell composition (reference based)	Beta values	ug/L	Illumina HumanMethylationEPIC	Cord blood	No reported associations in female only analysis	182	3	Infants	Both	East Asian	cg06319903	chr14:103477661	14	103477661	CDC42BPB	Open sea	-0.0211	0.0041	0.00000029	None	33515580_Park-J_prenatal_lead_exposure_meta-analysis_in_males_only
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0423242	0.00824917	0.0000002923127	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0547056	0.0106665	0.0000002954093	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	0.0423003	0.00824918	0.000000296845	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	1.1	0.22	0.0000003	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0439001	0.00857957	0.0000003146526	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0421994	0.00824922	0.0000003167427	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0443464	0.00866911	0.00000031694	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05734220	chr14:103524410	14	103524410	CDC42BPB	Island	0.0031	0.00061	0.00000032	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0421573	0.00824923	0.0000003254196	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10258505	chr14:103469439	14	103469439	CDC42BPB	Open sea	-0.00033	0.000064	0.00000033	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15988734	chr14:103411822	14	103411822	CDC42BPB	Open sea	-0.00017	0.000034	0.00000033	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0745529	0.0145993	0.0000003321174	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0443204	0.00869134	0.0000003450325	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10124651	chr14:103523278	14	103523278	CDC42BPB	Island	-0.0420606	0.00824926	0.0000003462304	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.042051	0.00824927	0.0000003483615	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0542364	0.0106441	0.0000003523005	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.042024	0.00824928	0.0000003544512	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.042023	0.00824928	0.0000003546634	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.0420089	0.00824928	0.000000357884	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0419703	0.0082493	0.0000003668201	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.043759	0.00860277	0.0000003689938	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Huang D	BHS, GSH, DILGOM, ETS, EGCUT (Asthma), EGCUT (Young_O), FTC, HBCS,JHS, NTR, PREVEND, YFS, EpiGO, LACHY	32520614	2020-11-12	Systolic Blood Pressure	EFO_0006335	Discovery	Table 2, table 3	DNA methylation	Systolic Blood Pressure	age, sex, ancestry, body mass index, cell composition (reference based)	Beta Values	mmHg	Illumina HumanMethylation450	Whole blood	Includes some twins	4820	15	Adults	Both	European, Admixed	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	None	None	0.00000037	None	32520614_Huang-D_systolic_blood_pressure_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.1	0.0201	0.00000037	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0419545	0.0082493	0.0000003705442	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18358952	chr14:103468050	14	103468050	CDC42BPB	Open sea	0.0015	None	0.00000038	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	-0.0418923	0.00824932	0.0000003855533	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.00385	0.00076	0.00000039	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21164005	chr14:103410594	14	103410594	CDC42BPB	South shelf	0.03087	0.00588	0.00000039	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18931727	chr14:103512157	14	103512157	CDC42BPB	Open sea	-0.0418422	0.00824934	0.0000003980813	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.12	0.0236	0.0000004	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0418316	0.00824934	0.0000004007707	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04569190	chr14:103422560	14	103422560	CDC42BPB	Open sea	0.01372	0.00262	0.00000041	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0501295	0.00990267	0.0000004194159	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.0417597	0.00824937	0.0000004195453	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.0417594	0.00824937	0.0000004196255	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.0426313	0.00842916	0.0000004296927	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10258505	chr14:103469439	14	103469439	CDC42BPB	Open sea	-0.0417139	0.00824938	0.0000004319298	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18733798	chr14:103469879	14	103469879	CDC42BPB	Open sea	0.0416683	0.0082494	0.0000004446124	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.0426214	0.00845288	0.0000004656065	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0436199	0.00865284	0.0000004683705	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0436605	0.00866865	0.0000004795039	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0712448	0.0141501	0.0000004836671	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0415306	0.00824945	0.0000004851547	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0415106	0.00824945	0.0000004913269	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0006725	0.00013304	0.000000506	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Liver Cirrhosis	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Liver Cirrhosis	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18325	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.011	0.0022	0.00000051	None	Robert-F-Hillary_Incident_Liver_Cirrhosis_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0414328	0.00824948	0.0000005160948	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0413939	0.00824949	0.0000005289138	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.004	0.00079	0.00000053	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27028800	chr14:103411330	14	103411330	CDC42BPB	Open sea	0.041381	0.0082495	0.0000005332564	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04430	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04430	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0413581	0.00824951	0.0000005409803	P04430	41361833_Josephine_Robertson_P04430_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0413414	0.00824951	0.0000005467245	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0429443	0.00857655	0.0000005587732	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0412913	0.00824953	0.0000005642465	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0412711	0.00824954	0.0000005714623	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0433814	0.0086716	0.0000005718904	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0433182	0.00866232	0.0000005776387	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.0412351	0.00824955	0.0000005845493	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0412348	0.00824955	0.0000005846504	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0412325	0.00824955	0.0000005854887	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.0412293	0.00824955	0.0000005866938	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg21373811	chr14:103498437	14	103498437	CDC42BPB	Open sea	-0.1383837	0.0277097	0.0000005913	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02995680	chr14:103430766	14	103430766	CDC42BPB	Island	-0.01036	0.00201	0.00000061	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09341108	chr14:103459720	14	103459720	CDC42BPB	Open sea	0.0411577	0.00824958	0.000000613638	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.041123	0.00824959	0.0000006271576	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Karlsson Linner R	-	29086770	2017-10-31	Educational attainment	EFO_0004784	Basic model	Table S1.6b	DNA methylation	Educational attainment	Age, sex, cell counts and technical covariates	Beta values	years of schooling	Illumina HumanMethylation450	Whole blood	-	10767	27	57	Both	None	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-	-	0.000000629	-	29086770_educational_attainment_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0410588	0.00824961	0.0000006528838	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0475248	0.00954976	0.0000006546338	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0431361	0.00866818	0.0000006552084	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0410515	0.00824961	0.000000655873	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0559622	0.0112467	0.0000006568706	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0410378	0.00824962	0.0000006615427	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.237297	0.0477594	0.0000006808452	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0425066	0.00855454	0.0000006809401	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0409629	0.00824964	0.0000006932472	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0426205	0.00858525	0.0000006969115	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0409501	0.00824965	0.0000006987957	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_1
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0345	0.00664	0.0000007	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0520853	0.0104937	0.0000007000964	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0409451	0.00824965	0.0000007009978	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.042363	0.00854269	0.0000007165718	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0524506	0.0105783	0.000000718984	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0481829	0.0097229	0.0000007290886	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	0.0408755	0.00824967	0.0000007320892	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0318	0.00612	0.00000074	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0408546	0.00824968	0.0000007417017	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16334456	chr14:103436635	14	103436635	CDC42BPB	Open sea	0.0408504	0.00824968	0.0000007436345	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0424925	0.00858725	0.0000007568383	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	0.00094	None	0.00000076	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.203161	0.0410829	0.0000007680036	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	-0.0407944	0.0082497	0.0000007700344	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.200118	0.0404756	0.0000007718706	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0427317	0.00864378	0.000000775274	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0407784	0.0082497	0.0000007777224	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg16209303	chr14:103405847	14	103405847	CDC42BPB	North shore	-1.229896	0.249	0.00000078	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	-0.0407718	0.00824971	0.0000007809334	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.0903182	0.0182949	0.0000008015695	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.050541	0.0102388	0.0000008053074	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	0.0446591	0.00905377	0.0000008200841	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0406836	0.00824974	0.0000008249256	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0406822	0.00824974	0.0000008256169	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18931727	chr14:103512157	14	103512157	CDC42BPB	Open sea	-0.040653	0.00824975	0.0000008407331	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0405852	0.00824977	0.0000008767872	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18931727	chr14:103512157	14	103512157	CDC42BPB	Open sea	-0.0417444	0.00849215	0.0000008944727	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.235269	0.0478891	0.0000009056586	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0677496	0.013791	0.0000009084569	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0710574	0.0144716	0.0000009199652	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0404759	0.00824981	0.0000009381082	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0423637	0.00863486	0.0000009389168	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0531862	0.0108433	0.0000009443092	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.046311	0.00944229	0.000000946051	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-0.0058	0.0012	0.00000097	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	-0.0413487	0.00844377	0.000000983711	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0409109	0.00835991	0.000001000103	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0403651	0.00824984	0.000001004484	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	-0.0403173	0.00824986	0.000001034483	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0403064	0.00824986	0.000001041496	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0484884	0.00992647	0.000001046499	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.126941	0.0260116	0.00000106934	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0402575	0.00824988	0.00000107325	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0459724	0.00942132	0.000001074118	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.22906	0.047	0.00000109	-	27105112_hiv_infection_neutrophils
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0402191	0.00824989	0.000001098884	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0056	0.0011	0.0000011	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04899282	chr14:103523516	14	103523516	CDC42BPB	Island	0.003	0.00062	0.0000011	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.063	0.01292	0.0000011	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.29	0.0597	0.0000011	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0420571	0.00863102	0.000001111851	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07167192	chr14:103524430	14	103524430	CDC42BPB	Island	0.0401998	0.0082499	0.000001111985	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.0401666	0.00824991	0.000001134847	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0401331	0.00824992	0.000001158394	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0401307	0.00824992	0.00000116012	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0505808	0.0103985	0.000001160835	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0421341	0.00867139	0.000001192114	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Lung Cancer	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Lung Cancer	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18364	1	Adults (18-65y)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	-0.022	0.00447	0.0000012	None	Robert-F-Hillary_Incident_Lung_Cancer_Basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	-0.263098	0.0541675	0.000001200944	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0413091	0.00850699	0.000001210737	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0400445	0.00824995	0.000001223	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0400335	0.00824995	0.000001231243	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	-0.047598	0.00981252	0.000001242618	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0418828	0.00864743	0.000001289496	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16334456	chr14:103436635	14	103436635	CDC42BPB	Open sea	-0.0016	0.00033	0.0000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.169484	0.0350135	0.000001305455	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0418463	0.00864488	0.000001307721	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0399248	0.00824999	0.000001315742	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.042042	0.00868796	0.000001317516	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.0399223	0.00824999	0.000001317758	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0399221	0.00824999	0.000001317929	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0413399	0.00854349	0.000001319772	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0418401	0.00864955	0.000001329825	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0399009	0.00825	0.000001335067	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0398967	0.00825	0.00000133848	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.039895	0.00825	0.000001339817	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0398815	0.00825	0.000001350901	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0666588	0.0137911	0.000001355512	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0398425	0.00825002	0.000001383345	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14533120	chr14:103447664	14	103447664	CDC42BPB	Open sea	0.0071	None	0.0000014	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg02938407	chr14:103486904	14	103486904	CDC42BPB	Open sea	-0.15027	0.0311359	0.000001402499	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0398153	0.00825002	0.000001406496	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0514856	0.0106689	0.00000140857	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0397946	0.00825003	0.000001424247	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.0404819	0.00839886	0.00000145047	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0397592	0.00825004	0.00000145524	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0638401	0.0132482	0.000001458967	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0397153	0.00825006	0.000001494571	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Rheumatoid Arthritis (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Rheumatoid Arthritis (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18055	1	Adults (18-65y)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.1	0.0216	0.0000015	None	Robert-F-Hillary_Prevalent_Rheumatoid_Arthritis_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.039709	0.00825006	0.000001500315	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.0396882	0.00825007	0.000001519323	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0396648	0.00825007	0.000001541018	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.0396523	0.00825008	0.000001552802	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0396365	0.00825008	0.00000156775	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0396102	0.00825009	0.000001592832	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-0.039608	0.00825009	0.000001595034	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0419704	0.0087423	0.000001595566	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.252378	0.0526085	0.000001621674	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0398165	0.00829935	0.000001622092	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.0395683	0.00825011	0.000001633801	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0395037	0.00825013	0.000001698848	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19582115	chr14:103436037	14	103436037	CDC42BPB	Open sea	0.0027	None	0.0000017	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13114471	chr14:103411216	14	103411216	CDC42BPB	Open sea	0.03946	0.00825014	0.000001744185	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0517102	0.0108205	0.000001779405	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-0.0398008	0.00833034	0.000001789256	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0413045	0.00864552	0.000001791569	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Lung Cancer	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Lung Cancer	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18364	1	Adults (18-65y)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.017	0.00354	0.0000018	None	Robert-F-Hillary_Incident_Lung_Cancer_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.0394075	0.00825016	0.000001800346	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0449118	0.00941028	0.000001835816	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0393691	0.00825017	0.00000184237	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.0393394	0.00825018	0.00000187566	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.209591	0.0439745	0.000001892568	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0393218	0.00825019	0.000001895629	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0393213	0.00825019	0.000001896194	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	IL2RB protein levels (SeqId = 9343-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL2RB protein levels (SeqId = 9343-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-2 receptor subunit beta	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.87	0.182	0.0000019	None	Gadd-DA_il2rb_protein_levels__seqid___9343-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0392672	0.0082502	0.000001958797	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0406436	0.00853968	0.000001960409	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.181833	0.0382127	0.000001966611	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0392548	0.00825021	0.000001973519	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18931727	chr14:103512157	14	103512157	CDC42BPB	Open sea	-0.0392546	0.00825021	0.000001973743	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07167192	chr14:103524430	14	103524430	CDC42BPB	Island	0.00028	None	0.000002	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	0.022	0.00455	0.000002	None	Robert-F-Hillary_Incident_COPD_Basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.045	0.00943	0.000002	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0411991	0.00866451	0.000002004024	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10124651	chr14:103523278	14	103523278	CDC42BPB	Island	0.099705	0.0209765	0.000002018667	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09341108	chr14:103459720	14	103459720	CDC42BPB	Open sea	0.0391341	0.00825025	0.000002121502	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	0.0390806	0.00825026	0.000002190534	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.039076	0.00825027	0.000002196567	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0691184	0.0145941	0.000002199487	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg12932547	chr14:103427159	14	103427159	CDC42BPB	North shelf	-0.0122	0.00246	0.0000022	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0689957	0.0145685	0.000002200763	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0390668	0.00825027	0.000002208688	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0390474	0.00825027	0.000002234429	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.0390179	0.00825028	0.000002274216	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg27028800	chr14:103411330	14	103411330	CDC42BPB	Open sea	-0.224129	0.0474258	0.000002309098	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0409528	0.0086703	0.000002341439	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0552069	0.0116892	0.000002346772	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10258505	chr14:103469439	14	103469439	CDC42BPB	Open sea	0.0389327	0.00825031	0.000002392635	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0403595	0.00855307	0.000002395353	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16334456	chr14:103436635	14	103436635	CDC42BPB	Open sea	-0.01	0.0022	0.0000024	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0389213	0.00825032	0.000002409044	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18733798	chr14:103469879	14	103469879	CDC42BPB	Open sea	0.0389174	0.00825032	0.00000241462	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.0393813	0.00835894	0.000002484257	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.0388685	0.00825033	0.000002485902	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0511553	0.0108606	0.00000249785	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26403748	chr14:103406333	14	103406333	CDC42BPB	Island	-0.00038	0.00008	0.0000025	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0388393	0.00825034	0.00000252948	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	0.0442769	0.00940641	0.000002535708	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	2	0.415	0.0000026	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	PUF60 protein levels (SeqId = 10575-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PUF60 protein levels (SeqId = 10575-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Poly(U)-binding-splicing factor PUF60	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.86	0.182	0.0000026	None	Gadd-DA_puf60_protein_levels__seqid___10575-31__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.038782	0.00825036	0.000002617083	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0387802	0.00825036	0.000002619831	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0407574	0.00867205	0.000002627069	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.038771	0.00825036	0.00000263418	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10258505	chr14:103469439	14	103469439	CDC42BPB	Open sea	0.038738	0.00825037	0.000002686268	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16058220	chr14:103490442	14	103490442	CDC42BPB	Open sea	0.0387378	0.00825037	0.000002686618	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0387136	0.00825038	0.000002725384	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	-0.038704	0.00825039	0.00000274093	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.065727	0.0140119	0.000002746118	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0386985	0.00825039	0.000002749927	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0679749	0.0144988	0.000002779281	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0478639	0.0102099	0.000002783806	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.0037	None	0.0000028	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	0.0056	None	0.0000028	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0407016	0.00868445	0.000002801126	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.240369	0.0513244	0.000002842961	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	-0.0386416	0.0082504	0.000002844051	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0500318	0.0106882	0.000002879886	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Ma J	CHARGE	32525743	2020-08-01	Healthy eating	EFO_0002755	European meta-analysis	Table 1	DNA methylation	Healthy eating	Age, sex, energy intake, cell composition (reference based), batch effects	Beta values	Alternative Healthy Eating Index	Illumina HumanMethylation450	Whole blood, CD4+ T-cells, CD14+ monocytes	See supplement of paper for details on diet scores	6662	5	Adults	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.001	0.0003	0.0000029	None	32525743_Ma-J_healthy_eating_european_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0386055	0.00825042	0.000002905393	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0385886	0.00825042	0.000002934629	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0404894	0.00865769	0.000002941232	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13114471	chr14:103411216	14	103411216	CDC42BPB	Open sea	0.0385798	0.00825042	0.000002949855	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	0.256838	0.0549381	0.000002961051	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0385642	0.00825043	0.000002977196	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.038564	0.00825043	0.000002977573	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0385567	0.00825043	0.000002990404	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0709797	0.0151923	0.000003007935	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0385309	0.00825044	0.000003036351	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	-0.0405448	0.00868781	0.000003085436	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0385002	0.00825045	0.00000309171	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13971	1	Adults (18-65y)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.064	0.01364	0.0000031	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26669125	chr14:103432390	14	103432390	CDC42BPB	South shore	0.0384788	0.00825046	0.000003131108	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0403934	0.0086633	0.000003150183	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.054508	0.0116938	0.000003169998	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.0392055	0.00841347	0.000003192131	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0384294	0.00825047	0.000003223436	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0384221	0.00825047	0.000003237285	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0572174	0.0122868	0.000003239473	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0398712	0.00856413	0.000003258684	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0572532	0.0123055	0.000003305487	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	-0.0383828	0.00825049	0.000003313089	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.101941	0.0219158	0.000003319952	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	0.0383705	0.00825049	0.000003337029	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10087771	chr14:103399429	14	103399429	CDC42BPB	South shelf	0.0383491	0.0082505	0.00000337927	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CBLN4 protein levels (SeqId = 5688-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBLN4 protein levels (SeqId = 5688-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cerebellin-4	774	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.58	0.125	0.0000034	None	Gadd-DA_cbln4_protein_levels__seqid___5688-65__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.0432389	0.00931705	0.000003500078	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0382834	0.00825052	0.00000351223	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0498286	0.0107511	0.000003604523	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16058220	chr14:103490442	14	103490442	CDC42BPB	Open sea	0.0382331	0.00825053	0.000003617338	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.0382229	0.00825054	0.000003638891	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0382187	0.00825054	0.000003647973	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0449112	0.00969827	0.000003672989	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0493443	0.0106584	0.000003695121	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	-0.117553	0.0254156	0.000003767521	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26103168	chr14:103507914	14	103507914	CDC42BPB	Open sea	0.0024	None	0.0000038	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0381248	0.00825057	0.000003853858	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.073	0.0158	0.0000039	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Christiansen C	TwinsUK, NSHD, NCDS1, NCDS2, BCS70	33593402	2021-02-16	Smoking	EFO_0004318, EFO_0006527	Current vs never smoking meta-analysis in European samples	Table S1	DNA methylation	Smoking	Sex, cell composition (reference based), body mass index, batch effects, relatedness	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	912	5	Adults	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	None	None	0.0000039	None	33593402_Christiansen-C_smoking_current_vs_never_smoking_meta-analysis_in_european_samples
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0501448	0.0108576	0.000003900031	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16716542	chr14:103453570	14	103453570	CDC42BPB	Open sea	0.0380836	0.00825058	0.000003947758	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0474047	0.0102755	0.000003995521	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0380495	0.00825059	0.00000402718	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.25983	0.056353	0.000004040992	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.0385944	0.00837622	0.000004107364	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0696399	0.0151259	0.000004178898	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	0.041023	0.00891142	0.000004190875	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0650949	0.0141423	0.000004202521	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	-0.0399668	0.00868315	0.000004203436	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.12	0.0262	0.0000043	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04899282	chr14:103523516	14	103523516	CDC42BPB	Island	-0.0609634	0.013263	0.000004332168	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.039861	0.00867931	0.00000441305	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16058220	chr14:103490442	14	103490442	CDC42BPB	Open sea	-0.0378866	0.00825064	0.0000044275	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0396194	0.00864065	0.00000457217	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02995680	chr14:103430766	14	103430766	CDC42BPB	Island	-0.0035	0.00076	0.0000046	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0378121	0.00825067	0.000004623317	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.0378098	0.00825067	0.000004629477	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.039919	0.00871261	0.000004649131	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0498573	0.0108863	0.000004691757	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0377628	0.00825068	0.00000475729	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0427994	0.00936253	0.000004885601	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0401424	0.008784	0.000004918259	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0391251	0.00856287	0.000004936897	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01100318	chr14:103469348	14	103469348	CDC42BPB	Open sea	0.213626	0.0467774	0.000004984891	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0376803	0.00825071	0.000004989671	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	0.0383193	0.00839319	0.000005023095	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0485798	0.0106421	0.000005038705	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0376513	0.00825072	0.000005074195	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0433573	0.00950114	0.000005074519	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.0384	0.00841561	0.000005085002	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26975587	chr14:103430286	14	103430286	CDC42BPB	North shore	-0.0023	0.00051	0.0000051	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.0420124	0.00921139	0.000005134203	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0664084	0.014566	0.000005178219	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0376034	0.00825073	0.000005216275	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0418123	0.00917456	0.000005220474	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0375998	0.00825073	0.000005227101	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0375916	0.00825074	0.000005251862	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FAP protein levels (SeqId = 5029-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAP protein levels (SeqId = 5029-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prolyl endopeptidase FAP	774	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.57	0.125	0.0000053	None	Gadd-DA_fap_protein_levels__seqid___5029-3__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0054	0.0012	0.0000053	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0375699	0.00825074	0.000005317938	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.0387671	0.00851783	0.00000537461	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04899282	chr14:103523516	14	103523516	CDC42BPB	Island	-0.0375439	0.00825075	0.000005398423	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	0.0375365	0.00825075	0.000005421482	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	2.2	0.484	0.0000056	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0641897	0.0141347	0.000005636075	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.039265	0.00865043	0.000005695009	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16058220	chr14:103490442	14	103490442	CDC42BPB	Open sea	-0.0374496	0.00825078	0.000005699342	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NCR1 protein levels (SeqId = 8360-169)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NCR1 protein levels (SeqId = 8360-169)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Natural cytotoxicity triggering receptor 1	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.82	0.182	0.0000057	None	Gadd-DA_ncr1_protein_levels__seqid___8360-169__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0492792	0.0108628	0.000005764636	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0388671	0.00856858	0.000005778403	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0373738	0.0082508	0.000005952806	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Aghagoli G	The Neonatal Neurobehavior and Outcomes in Very Preterm Infants	32967004	07-04-2021	cry acoustics factor 1	None	None	Supplementary Table 1	cry acoustics factor 1	DNA methylation	Sex, PMA, recruitment site, proportions of epithelial cells	None	Beta values	Illumina HumanMethylationEPIC	Buccal	None	335	1	Infants	Both	European	cg04987955	chr14:103438392	14	103438392	CDC42BPB	Open sea	0.003	0.001	0.000006	None	32967004_Aghagoli-G_cry_acoustics_factor_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10239600	chr14:103411866	14	103411866	CDC42BPB	Open sea	0.00067	None	0.000006	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0373585	0.00825081	0.000006005385	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0373492	0.00825081	0.000006037359	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0443936	0.00980918	0.000006066167	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0373336	0.00825082	0.000006091612	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.204057	0.0451161	0.000006139463	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	0.0373108	0.00825082	0.000006171922	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P13671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P13671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.037304	0.00825082	0.000006195816	P13671	41361833_Josephine_Robertson_P13671_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.0099	0.0022	0.0000062	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0372758	0.00825083	0.000006296761	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0470593	0.0104189	0.000006329504	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0372581	0.00825084	0.000006360842	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0372544	0.00825084	0.000006374322	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0491347	0.0108883	0.000006452661	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0389046	0.00862343	0.000006487031	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0372232	0.00825085	0.00000648899	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16561957	chr14:103430940	14	103430940	CDC42BPB	South shore	-0.0029	0.00065	0.0000065	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.0371989	0.00825086	0.000006579538	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24755931	chr14:103407195	14	103407195	CDC42BPB	South shore	-0.01942	0.00419	0.0000066	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.03719	0.00825086	0.000006613019	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0412915	0.00916191	0.000006630033	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0392722	0.00871737	0.000006686954	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14448215	chr14:103465967	14	103465967	CDC42BPB	Open sea	-0.0039	0.00088	0.0000067	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0390108	0.00866104	0.000006714883	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0488369	0.0108442	0.000006735615	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg01198184	chr14:103433908	14	103433908	CDC42BPB	South shelf	-0.155912	0.0346291	0.00000676313	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	0.965132	0.2145	0.00000678	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0371453	0.00825087	0.000006783974	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19589358	chr14:103410516	14	103410516	CDC42BPB	South shelf	0.0371428	0.00825087	0.000006793684	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.0371372	0.00825088	0.000006815408	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.037114	0.00825088	0.000006906407	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg16209303	chr14:103405847	14	103405847	CDC42BPB	North shore	-0.00022602	5e-05	0.00000691	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0371058	0.00825089	0.00000693868	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0539642	0.0119998	0.000006942134	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09341108	chr14:103459720	14	103459720	CDC42BPB	Open sea	0.037103	0.00825089	0.000006949468	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0389997	0.008673	0.000006955251	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.0370932	0.00825089	0.000006988743	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.0370765	0.00825089	0.000007055491	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0370668	0.0082509	0.000007094238	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0430449	0.00958186	0.00000709859	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0417529	0.00929743	0.000007149624	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0370421	0.00825091	0.000007194699	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0370257	0.00825091	0.00000726214	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0370214	0.00825091	0.000007280106	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.0370161	0.00825091	0.000007301885	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.193533	0.0431461	0.000007320115	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	0.037003	0.00825092	0.000007356701	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0370019	0.00825092	0.000007361046	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0369651	0.00825093	0.000007516556	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.036959	0.00825093	0.000007542892	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.0369576	0.00825093	0.000007548805	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0369386	0.00825094	0.000007630775	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	0.0369299	0.00825094	0.000007668509	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0646454	0.0144524	0.000007771335	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01009	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01009	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0368969	0.00825095	0.000007813282	P01009	41361833_Josephine_Robertson_P01009_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	-0.0368752	0.00825096	0.000007909948	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.0379755	0.00850119	0.000007988859	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0364147	0.00815196	0.000007992207	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.0368559	0.00825096	0.000007996738	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	-0.271284	0.0607455	0.000008023108	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0368432	0.00825097	0.000008054734	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0368372	0.00825097	0.00000808179	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0368132	0.00825097	0.000008192704	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	-0.20714	0.0464827	0.000008389146	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.0476466	0.0106934	0.00000842357	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0464319	0.0104231	0.000008463425	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0643023	0.0144394	0.000008520743	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg17556255	chr14:103475251	14	103475251	CDC42BPB	Open sea	-0.167155	0.03754	0.000008529799	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.100801	0.0226458	0.000008589576	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.0367273	0.008251	0.000008599824	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.0370924	0.00833549	0.000008652769	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	0.161349	0.0362633	0.000008666105	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.196205	0.0441025	0.000008687441	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21164005	chr14:103410594	14	103410594	CDC42BPB	South shelf	0.0367067	0.00825101	0.00000870069	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	-0.0374386	0.00841559	0.000008701835	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0367039	0.00825101	0.000008714218	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-0.0367009	0.00825101	0.000008729015	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.0366787	0.00825102	0.000008839071	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0366449	0.00825103	0.000009009109	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0366315	0.00825103	0.000009077085	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0366212	0.00825103	0.000009129907	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0049	None	0.0000092	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0372575	0.00840192	0.000009299843	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Concentration of very large VLDL particles	EFO_0004611	None	None	DNA methylation	Concentration of very large VLDL particles	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mol/l	Illumina HumanMethylation450	Whole blood	None	616	1	Adults	Females	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	380000000	85000000	0.0000093	None	Battram-T_concentration_of_very_large_vldl_particles
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	0.0365876	0.00825104	0.000009304482	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14533120	chr14:103447664	14	103447664	CDC42BPB	Open sea	0.011	0.0026	0.0000094	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0365483	0.00825106	0.000009512296	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0365404	0.00825106	0.000009554531	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.24841	0.056151	0.000009749779	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.0365043	0.00825107	0.000009750021	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0365038	0.00825107	0.000009753146	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0364984	0.00825107	0.000009782749	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CILP2 protein levels (SeqId = 8841-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CILP2 protein levels (SeqId = 8841-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cartilage intermediate layer protein 2	774	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.82	0.185	0.0000098	None	Gadd-DA_cilp2_protein_levels__seqid___8841-65__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04987955	chr14:103438392	14	103438392	CDC42BPB	Open sea	0.00079	None	0.0000098	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	-0.043418	0.00981633	0.000009802236	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	0.0364802	0.00825108	0.000009882754	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.0364668	0.00825108	0.00000995771	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Paolo Reho	None	None	None	Lewy body dementia	None	None	None	DNA methylation	Lewy body dementia	Age, Sex, Cell composition (reference based), Batch effects, Ancestry (genomic PCs)	Beta values	None	Illumina HumanMethylationEPIC	Cerebellar tissue	None	450	1	Geriatrics	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0092	0.00207	0.00001	None	Reho-P_lewy_body_dementia
Lin Y	Patients recruited at The First Affiliated Hospital of Sun Yat-sen University	33319642	2021-07-01	IgA nephropathy	EFO_0004194, EFO_0003086, HP_0000112	None	Supplementary Table S1.EWAS	DNA methylation	IgA nephropathy	Age, Sex, Smoking, Cell composition (reference based), Batch effects	Beta Values	None	Illumina HumanMethylationEPIC	CD19+ B cells	ethnicity not reported but QC checks were made against 1000 Genomes Project EAS population	184	1	Adults	Both	East Asian	cg18076919	chr14:103500365	14	103500365	CDC42BPB	Open sea	0.52	0.113	0.00001	None	33319642_Lin-Y_iga_nephropathy
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0364556	0.00825108	0.00001002007	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	-0.0364317	0.00825109	0.0000101555	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0364317	0.00825109	0.00001015561	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0364175	0.00825109	0.00001023628	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.0416342	0.00943342	0.00001024477	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0364018	0.0082511	0.00001032695	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	-0.0382004	0.00866007	0.00001035784	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0363923	0.0082511	0.00001038176	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18931727	chr14:103512157	14	103512157	CDC42BPB	Open sea	-0.0372447	0.00844721	0.0000104531	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0363741	0.00825111	0.00001048846	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0363618	0.00825111	0.0000105604	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0505507	0.0114753	0.00001064548	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14448215	chr14:103465967	14	103465967	CDC42BPB	Open sea	0.0363449	0.00825112	0.00001066073	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg10291119	chr14:103403760	14	103403760	CDC42BPB	North shelf	-0.00015208	3.44e-05	0.0000107	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.995809	0.2263	0.0000108	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	-0.0363169	0.00825112	0.000010829	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0363036	0.00825113	0.00001090955	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	0.0384761	0.00874527	0.00001091906	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_4
Battram T	GEO	23334450	2020-09-15	Rheumatoid arthritis	EFO_0000685	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE42861	None	DNA methylation	Rheumatoid arthritis	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	689	1	Adults	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0192	0.00432	0.000011	None	23334450_Battram-T_rheumatoid_arthritis_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse42861
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	0.00331	0.00075	0.000011	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	CECR1 protein levels (SeqId = 6077-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CECR1 protein levels (SeqId = 6077-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adenosine deaminase 2	774	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.77	0.175	0.000011	None	Gadd-DA_cecr1_protein_levels__seqid___6077-63__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	0.0371956	0.00845766	0.0000110091	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0443378	0.010083	0.00001103756	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.0362775	0.00825114	0.00001106993	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0469409	0.0106847	0.00001124291	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.0362329	0.00825115	0.00001134881	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-0.0362056	0.00825116	0.00001152251	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0361923	0.00825116	0.0000116081	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0398073	0.00908803	0.00001193955	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0361377	0.00825118	0.00001196644	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0380239	0.00868236	0.00001198075	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0361346	0.00825118	0.00001198741	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CILP2 protein levels (SeqId = 8841-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CILP2 protein levels (SeqId = 8841-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cartilage intermediate layer protein 2	774	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.55	0.125	0.000012	None	Gadd-DA_cilp2_protein_levels__seqid___8841-65__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Chronic Kidney Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Chronic Kidney Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18000	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.011	0.00249	0.000012	None	Robert-F-Hillary_Incident_Chronic_Kidney_Disease_Basic_model
Colicino E	CHARGE	32697766	07-22-2020	All cause mortality	EFO_0004352	basic model	Table S2	All cause mortality	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	None	M values	Illumina HumanMethylation450	Whole blood	Effect estimates represent hazard ratio per 10% increase in DNA methylation.	12300	12	Adults	Both	European, African	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	1.08	None	0.000012	None	32697766_Colicino-E_all_cause_mortality_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0361023	0.00825119	0.00001220423	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0360769	0.0082512	0.00001237763	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0372742	0.0085362	0.00001270571	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	-0.0360123	0.00825122	0.00001282938	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.046747	0.0107132	0.00001288825	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0359994	0.00825122	0.00001292183	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.0367762	0.00842978	0.00001293753	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0359887	0.00825122	0.00001299846	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	0.0021	0.00046	0.000013	None	33564054_Kashima-K_gestational_age
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10087771	chr14:103399429	14	103399429	CDC42BPB	South shelf	0.01689	0.00378	0.000013	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13971	1	Adults (18-65y)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.045	0.01041	0.000013	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.063048	0.0144564	0.00001302089	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0376536	0.00863635	0.0000131012	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	0.132741	0.0304486	0.0000131108	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04899282	chr14:103523516	14	103523516	CDC42BPB	Island	-0.0576072	0.0132151	0.0000131438	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q16610	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q16610	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0359677	0.00825123	0.00001315059	Q16610	41361833_Josephine_Robertson_Q16610_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0348462	0.00799442	0.00001316592	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0374383	0.00858932	0.00001317262	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0779447	0.0178836	0.00001318777	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	-0.0359458	0.00825124	0.00001331106	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0359355	0.00825124	0.000013387	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	C9JB55	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	C9JB55	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0601261	0.0138058	0.00001338824	C9JB55	41361833_Josephine_Robertson_C9JB55_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.229694	0.0527762	0.00001355397	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	0.035913	0.00825125	0.0000135542	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.041929	0.00963607	0.00001362735	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0800013	0.0183997	0.00001383294	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0375432	0.00863468	0.00001383421	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0415608	0.00955958	0.00001385931	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26669125	chr14:103432390	14	103432390	CDC42BPB	South shore	0.0358646	0.00825126	0.00001392205	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.29	0.0658	0.000014	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.0483974	0.0111408	0.00001407534	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0376499	0.00866751	0.00001409834	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.0358275	0.00825127	0.00001421011	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	-0.0358232	0.00825127	0.00001424355	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	0.0417334	0.00961405	0.00001428675	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg24755931	chr14:103407195	14	103407195	CDC42BPB	South shore	-0.237767	0.0548	0.0000143	None	27105112_hiv_infection_cd4_tcells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	0.0358089	0.00825128	0.00001435648	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.187274	0.0431565	0.0000143668	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01100318	chr14:103469348	14	103469348	CDC42BPB	Open sea	-0.0357909	0.00825128	0.00001449964	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	-0.0357804	0.00825128	0.0000145842	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0357782	0.00825129	0.00001460194	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	C9JB55	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	C9JB55	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0598375	0.013805	0.00001470684	C9JB55	41361833_Josephine_Robertson_C9JB55_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0616076	0.0142173	0.0000147885	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0357528	0.00825129	0.00001480767	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.035743	0.0082513	0.00001488711	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04569190	chr14:103422560	14	103422560	CDC42BPB	Open sea	0.0022	None	0.000015	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	1.5	0.351	0.000015	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0357151	0.0082513	0.00001511806	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0424972	0.00982483	0.00001531974	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.07069	0.0163475	0.00001540916	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_4
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	1.026538	0.2376	0.0000155	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.0356584	0.00825132	0.00001559651	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0356561	0.00825132	0.00001561647	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0629646	0.0145762	0.00001572751	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0356376	0.00825133	0.0000157756	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.035632	0.00825133	0.00001582458	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0356172	0.00825133	0.00001595322	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Breast Cancer (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Breast Cancer (Self-report)	Age, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	10650	1	Adults (18-65y)	Females	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	-0.11	0.0251	0.000016	None	Robert-F-Hillary_Prevalent_Breast_Cancer_(Self-report)_Basic_model
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-1.5	0.346	0.000016	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.0355999	0.00825134	0.00001610534	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	-0.0372032	0.00862397	0.00001614328	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	0.0355827	0.00825134	0.00001625845	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	-0.0355797	0.00825134	0.00001628488	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.037184	0.00862911	0.00001649675	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21937244	chr14:103406412	14	103406412	CDC42BPB	Island	-0.0355493	0.00825135	0.00001655827	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	-0.0355447	0.00825135	0.00001660004	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0355428	0.00825135	0.00001661742	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Green BB	-	26771251	2016-08-01	Arsenic exposure	OBI_0002416	Placenta	Table S2	DNA methylation	Arsenic exposure	Offspring sex, maternal age, gestational age and cell counts	Beta values	mug/kg	Illumina HumanMethylation450	Placenta	Arsenic exposure was measured in the placenta	285	1	31.5	Females	European	cg21164005	chr14:103410594	14	103410594	CDC42BPB	South shelf	0.0063	0.00146	0.0000167	-	26771251_arsenic_exposure_placenta
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	0.0355234	0.00825136	0.00001679492	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	0.11	0.0255	0.000017	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	1.6	0.381	0.000017	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.023	0.00527	0.000017	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	KREMEN1 protein levels (SeqId = 17331-138)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KREMEN1 protein levels (SeqId = 17331-138)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kremen protein 1	774	1	Adults (18-65 years)	Both	European	cg26403748	chr14:103406333	14	103406333	CDC42BPB	Island	-0.89	0.207	0.000017	None	Gadd-DA_kremen1_protein_levels__seqid___17331-138__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0355002	0.00825137	0.00001700988	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	0.0354967	0.00825137	0.00001704195	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.0354895	0.00825137	0.00001710959	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0354565	0.00825138	0.0000174208	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0457528	0.0106492	0.00001747363	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20521220	chr14:103442892	14	103442892	CDC42BPB	Open sea	0.0354418	0.00825138	0.00001756164	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	0.0393348	0.00915905	0.00001761041	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	0.111328	0.025936	0.00001777009	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	ADAM22 protein levels (SeqId = 7933-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADAM22 protein levels (SeqId = 7933-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Disintegrin and metalloproteinase domain-containing protein 22	774	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.54	0.125	0.000018	None	Gadd-DA_adam22_protein_levels__seqid___7933-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADAM22 protein levels (SeqId = 7933-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADAM22 protein levels (SeqId = 7933-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Disintegrin and metalloproteinase domain-containing protein 22	774	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.79	0.185	0.000018	None	Gadd-DA_adam22_protein_levels__seqid___7933-75__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09985481	chr14:103411899	14	103411899	CDC42BPB	Open sea	0.0014	None	0.000018	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0353857	0.0082514	0.00001810728	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0366137	0.00853781	0.0000181103	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	-0.0353755	0.0082514	0.00001820874	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Fragoso-Bargas Nicolas	EPIPREG (Epigenetics in pregnancy)	39844050	Jan 22, 2025	Moderate physical activity	EFO:0000001	discovery (step adjusted)	None	DNA methylation	Moderate physical activity	Age,Smoking,Cell composition (reference based)	M values	hours/day	Illumina HumanMethylationEPIC	Whole blood	analysis of pregnant women (gestational week 28)	353	1	Adults (18-65 years)	Females	European,South Asian	cg21231141	chr14:103411005	14	103411005	CDC42BPB	Open sea	0.1016156	0.02340487	0.0000187	None	39844050_Fragoso-Bargas-Nicolas_moderate_physical_activity_discovery_(step_adjusted)
Antoun E	UPBEAT	33151971	2020-11-05	gestational diabetes milletus	EFO_0004593	Adjusted for gestational age at OGTT	S1 Data Table H	gestational diabetes milletus	DNA methylation	Sex, ethnicity, cell composition (reference based), maternal smoking, maternal age, parity, gestational age at oral glucose tolerance test	None	Beta Values	Illumina HumanMethylationEPIC	Cord blood	None	557	1	Infants	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	0.79	0.182	0.000019	None	33151971_Antoun-E_gestational_diabetes_milletus_adjusted_for_gestational_age_at_ogtt
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0373174	0.00872433	0.00001902922	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0383598	0.00897133	0.00001916385	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0352738	0.00825143	0.00001924537	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0352599	0.00825144	0.00001939212	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	0.0352555	0.00825144	0.00001943778	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0352172	0.00825145	0.00001984742	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Stroke	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Stroke	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18023	1	Adults (18-65y)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.041	0.00964	0.00002	None	Robert-F-Hillary_Incident_Stroke_Basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg21164005	chr14:103410594	14	103410594	CDC42BPB	South shelf	0.035	0.0083	0.00002	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	EFNB2 protein levels (SeqId = 14131-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EFNB2 protein levels (SeqId = 14131-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ephrin-B2	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.78	0.182	0.00002	None	Gadd-DA_efnb2_protein_levels__seqid___14131-37__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	-0.035179	0.00825146	0.00002026238	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0391215	0.00917715	0.00002030282	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-0.0351656	0.00825146	0.00002041056	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0389467	0.0091406	0.00002049215	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.077897	0.0182839	0.00002051372	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.0351509	0.00825147	0.00002057399	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.0351436	0.00825147	0.00002065572	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0389235	0.00914037	0.00002071556	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0370027	0.00869037	0.00002076473	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0351273	0.00825148	0.00002083898	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	IL15RA protein levels (SeqId = 14054-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL15RA protein levels (SeqId = 14054-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-15 receptor subunit alpha	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.78	0.182	0.000021	None	Gadd-DA_il15ra_protein_levels__seqid___14054-17__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.0386557	0.00909228	0.00002136745	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.183217	0.0431151	0.00002153751	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Karlsson Linner R	-	29086770	2017-10-31	Educational attainment	EFO_0004784	Basic model	Table S1.6b	DNA methylation	Educational attainment	Age, sex, cell counts and technical covariates	Beta values	years of schooling	Illumina HumanMethylation450	Whole blood	-	10767	27	57	Both	None	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-	-	0.0000216	-	29086770_educational_attainment_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.0395353	0.00930654	0.00002168965	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.0358357	0.00843566	0.00002169031	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16058220	chr14:103490442	14	103490442	CDC42BPB	Open sea	-0.0350413	0.0082515	0.00002183241	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TNXB protein levels (SeqId = 5698-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNXB protein levels (SeqId = 5698-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tenascin-X	774	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.782	0.184	0.000022	None	Gadd-DA_tnxb_protein_levels__seqid___5698-60__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02995680	chr14:103430766	14	103430766	CDC42BPB	Island	-0.0350232	0.00825151	0.00002204692	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21373811	chr14:103498437	14	103498437	CDC42BPB	Open sea	0.0350229	0.00825151	0.00002204969	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.0349979	0.00825151	0.00002234946	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	-0.0349929	0.00825151	0.00002241095	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0437554	0.0103184	0.00002243866	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09341108	chr14:103459720	14	103459720	CDC42BPB	Open sea	0.0349792	0.00825152	0.00002257654	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0349627	0.00825152	0.0000227784	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04899282	chr14:103523516	14	103523516	CDC42BPB	Island	0.143323	0.0338323	0.00002284352	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.0428847	0.0101249	0.00002293685	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.12	0.0278	0.000023	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0359204	0.00848333	0.0000230732	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg16688466	chr14:103443987	14	103443987	CDC42BPB	Open sea	-0.19244	0.045474	0.00002328805	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0349209	0.00825154	0.00002329821	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0349134	0.00825154	0.00002339198	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27028800	chr14:103411330	14	103411330	CDC42BPB	Open sea	0.0349094	0.00825154	0.00002344236	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21937244	chr14:103406412	14	103406412	CDC42BPB	Island	0.0349076	0.00825154	0.00002346576	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.034896	0.00825154	0.00002361316	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0348903	0.00825154	0.00002368518	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0777058	0.0183895	0.00002397964	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12195230	chr14:103470300	14	103470300	CDC42BPB	Open sea	-0.00011	0.000027	0.000024	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Antoun E	UPBEAT	33151971	2020-11-05	1-hour glucose	EFO_0004468	None	S1 Data Table E	1-hour glucose	DNA methylation	Sex,ethnicity,cell counts (reference based),maternal smoking,maternal age, parity	None	Beta Values	Illumina HumanMethylationEPIC	Cord blood	None	557	1	Infants	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	-0.91553	0.21472	0.000024	None	33151971_Antoun-E_1-hour_glucose
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	-0.0348648	0.00825155	0.00002401222	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0610391	0.0144497	0.00002412058	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.183727	0.0435293	0.00002447141	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21373811	chr14:103498437	14	103498437	CDC42BPB	Open sea	0.034974	0.00828658	0.0000245166	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	-0.0434854	0.0103071	0.00002468864	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Ischemic Heart Disease (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Ischemic Heart Disease (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18059	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.067	0.0158	0.000025	None	Robert-F-Hillary_Prevalent_Ischemic_Heart_Disease_(Self-report)_Basic_model
Antoun E	UPBEAT	33151971	2020-11-05	gestational diabetes milletus	EFO_0004593	None	S1 Data Table C	gestational diabetes milletus	DNA methylation	Sex,ethnicity,cell counts (reference based),maternal smoking,maternal age, parity	None	Beta Values	Illumina HumanMethylationEPIC	Cord blood	None	557	1	Infants	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	0.52	0.123	0.000025	None	33151971_Antoun-E_gestational_diabetes_milletus
Antoun E	UPBEAT	33151971	2020-11-05	gestational diabetes milletus	EFO_0004593	Adjusted for intervention	S1 Data Table R	gestational diabetes milletus	DNA methylation	Sex,ethnicity,cell counts (reference based),maternal smoking,maternal age, parity,intervention	None	Beta Values	Illumina HumanMethylationEPIC	Cord blood	None	557	1	Infants	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	0.52	0.122	0.000025	None	33151971_Antoun-E_gestational_diabetes_milletus_adjusted_for_intervention
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0409302	0.00970935	0.0000250673	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.03478	0.00825158	0.00002513242	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	-0.0414174	0.00983406	0.00002550472	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	-0.0347436	0.00825159	0.0000256288	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.0347276	0.00825159	0.00002584918	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Stroke	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Stroke	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14175	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.018	0.00425	0.000026	None	Robert-F-Hillary_Incident_Stroke_Fully-adjusted_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02938407	chr14:103486904	14	103486904	CDC42BPB	Open sea	-0.00063	0.00015	0.000026	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	ARIES	None	2020-08-20	Total lipids in very large VLDL	EFO_0004529	None	None	DNA methylation	Total lipids in very large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	651	1	Adults	Females	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	3.5	0.82	0.000026	None	Battram-T_total_lipids_in_very_large_vldl
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.00989	0.00229	0.000026	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0412337	0.0098069	0.00002631437	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.0897339	0.0213441	0.00002633102	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.121068	0.0288036	0.00002644702	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0346792	0.00825161	0.00002652809	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.0587834	0.0139884	0.00002657833	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0346614	0.00825161	0.00002678208	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Chatziioannou A	EnviroGenomarkers project consortium	28225026	2017-02-22	Tobacco smoking	EFO_0006527, EFO_0005671, EFO_0004318	-	Table S2	DNA methylation	Current vs never smoking	Age, sex, body mass index, study centre and cell counts	M values	-	Illumina HumanMethylation450	Whole blood	-	454	2	52	Both	None	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-	-	0.0000268	-	28225026_tobacco_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0333408	0.00794015	0.00002696617	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0529962	0.0126281	0.0000272444	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.034605	0.00825163	0.00002760302	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.0769052	0.0183404	0.00002763935	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0345863	0.00825163	0.00002788027	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	-0.0345808	0.00825163	0.00002796247	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0345797	0.00825163	0.00002797891	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Antoun E	UPBEAT	33151971	2020-11-05	1-hour glucose	EFO_0004468	Adjusted for intervention	S1 Data Table Q	1-hour glucose	DNA methylation	Sex,ethnicity,cell counts (reference based),maternal smoking,maternal age, parity,intervention	None	Beta Values	Illumina HumanMethylationEPIC	Cord blood	None	557	1	Infants	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	-1.0572	0.24995	0.000028	None	33151971_Antoun-E_1-hour_glucose_adjusted_for_intervention
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0454517	0.010858	0.00002855763	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0345331	0.00825165	0.00002868412	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.038208	0.00913244	0.00002883891	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0362932	0.00867564	0.00002889156	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0352951	0.00843787	0.00002894292	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14448215	chr14:103465967	14	103465967	CDC42BPB	Open sea	-0.00716	0.00167	0.000029	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Antoun E	UPBEAT	33151971	2020-11-05	gestational diabetes milletus	EFO_0004593	Adjusted for BMI	S1 Data Table D	gestational diabetes milletus	DNA methylation	Sex,ethnicity,cell counts (reference based),maternal smoking,maternal age, parity,maternal BMI	None	Beta Values	Illumina HumanMethylationEPIC	Cord blood	None	557	1	Infants	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	0.39	0.094	0.000029	None	33151971_Antoun-E_gestational_diabetes_milletus_adjusted_for_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0362024	0.00865621	0.00002903223	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	0.0374805	0.00896225	0.00002905799	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P69905	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P69905	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0345087	0.00825165	0.00002905893	P69905	41361833_Josephine_Robertson_P69905_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0435343	0.0104104	0.00002908524	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0608888	0.0145639	0.00002921833	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0361101	0.00864	0.00002939541	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0344833	0.00825166	0.00002945518	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0344517	0.00825167	0.00002995436	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Cardenas A	Project Viva	31300640	Jul 12, 2019	fractional exhaled nitric oxide (FeNO)	EFO_0005536	None	Supplementary Data 2	DNA methylation	fractional exhaled nitric oxide (FeNO)	Age, Sex, Smoking, Cell composition (reference free), Batch effects, Ancestry (other), Body mass index, Education, sine and cosine of season at sample collection	Beta values	ppb	Illumina HumanMethylationEPIC	nasal epithelium	None	517	1	Children	Both	Other	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	1.9	0.451	0.00003	SE manually calculated	31300640_Cardenas-A_fractional_exhaled_nitric_oxide__feno_
Antoun E	UPBEAT	33151971	2020-11-05	1-hour glucose	EFO_0004468	Adjusted for gestational age at OGTT	S1 Data Table I	1-hour glucose	DNA methylation	Sex,ethnicity,cell counts (reference based),maternal smoking,maternal age, parity,gestational age at OGTT	None	Beta Values	Illumina HumanMethylationEPIC	Cord blood	None	557	1	Infants	Both	European	cg12822891	chr14:103464954	14	103464954	CDC42BPB	Open sea	-1.145	0.2718	0.00003	None	33151971_Antoun-E_1-hour_glucose_adjusted_for_gestational_age_at_ogtt
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00810024	chr14:103405778	14	103405778	CDC42BPB	North shore	0.0344409	0.00825167	0.00003012831	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0395021	0.00947091	0.00003051615	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0359659	0.00862783	0.00003082424	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	0.01119	0.00262	0.000031	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15988734	chr14:103411822	14	103411822	CDC42BPB	Open sea	-0.00316	0.00074	0.000031	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Aghagoli G	The Neonatal Neurobehavior and Outcomes in Very Preterm Infants	32967004	07-04-2021	cry acoustics factor 2	None	None	Supplementary Table 2	cry acoustics factor 2	DNA methylation	Sex, PMA, recruitment site, proportions of epithelial cells	None	Beta values	Illumina HumanMethylationEPIC	Buccal	None	335	1	Infants	Both	European	cg27028800	chr14:103411330	14	103411330	CDC42BPB	Open sea	0.044	0.011	0.000031	None	32967004_Aghagoli-G_cry_acoustics_factor_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0343667	0.00825169	0.00003134069	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16334456	chr14:103436635	14	103436635	CDC42BPB	Open sea	0.034363	0.0082517	0.00003140192	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.268997	0.0646324	0.00003170572	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0550489	0.0132277	0.00003177677	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.058759	0.0141202	0.00003181909	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-	-	0.0000319	-	26500701_sex_kora_f4
Gadd DA	Generation Scotland	35945220	31/07/2022	ANTXR1 protein levels (SeqId = 10464-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANTXR1 protein levels (SeqId = 10464-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Anthrax toxin receptor 1	774	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.77	0.185	0.000032	None	Gadd-DA_antxr1_protein_levels__seqid___10464-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	INTS3 protein levels (SeqId = 11934-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	INTS3 protein levels (SeqId = 11934-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Integrator complex subunit 3	774	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.9	0.216	0.000032	None	Gadd-DA_ints3_protein_levels__seqid___11934-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL2RB protein levels (SeqId = 9343-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL2RB protein levels (SeqId = 9343-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-2 receptor subunit beta	774	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.78	0.188	0.000032	None	Gadd-DA_il2rb_protein_levels__seqid___9343-16__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	-0.0048	0.0012	0.000032	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	0.0343241	0.00825171	0.00003205708	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0343204	0.00825171	0.00003211985	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0357264	0.00859304	0.00003234401	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0359602	0.0086494	0.00003235218	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Concentration of chylomicrons and extremely large VLDL particles	EFO_0008596	None	None	DNA methylation	Concentration of chylomicrons and extremely large VLDL particles	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mol/l	Illumina HumanMethylation450	Whole blood	None	623	1	Adults	Females	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	2000000000	490000000	0.000033	None	Battram-T_concentration_of_chylomicrons_and_extremely_large_vldl_particles
Battram T	ARIES	None	2020-08-20	Phospholipids in very large VLDL	EFO_0004639	None	None	DNA methylation	Phospholipids in very large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	622	1	Adults	Females	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	20.6	4.9	0.000033	None	Battram-T_phospholipids_in_very_large_vldl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21164005	chr14:103410594	14	103410594	CDC42BPB	South shelf	0.0342435	0.00825173	0.00003345663	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0342352	0.00825173	0.00003360283	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0342269	0.00825173	0.00003375059	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18211157	chr14:103469613	14	103469613	CDC42BPB	Open sea	0.0039	None	0.000034	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q16610	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q16610	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0359847	0.0086802	0.00003408275	Q16610	41361833_Josephine_Robertson_Q16610_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0421674	0.0101811	0.00003466383	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.0341659	0.00825175	0.00003485746	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0457228	0.01105	0.00003525668	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0391859	0.00947086	0.00003530313	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0341314	0.00825176	0.00003549816	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12932547	chr14:103427159	14	103427159	CDC42BPB	North shelf	0.0341287	0.00825176	0.00003554923	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0341244	0.00825176	0.00003563026	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.0345329	0.00835251	0.00003578121	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0396122	0.00958327	0.0000359313	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.041	0.00993	0.000036	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.034085	0.00825177	0.00003637874	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18931727	chr14:103512157	14	103512157	CDC42BPB	Open sea	-0.0340841	0.00825177	0.00003639469	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0358307	0.00867545	0.0000364578	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.039839	0.00964887	0.0000366552	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0352908	0.00854771	0.00003668645	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16334456	chr14:103436635	14	103436635	CDC42BPB	Open sea	0.0340681	0.00825178	0.00003670284	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	0.0340617	0.00825178	0.00003682683	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0340606	0.00825178	0.00003684832	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.0340597	0.00825178	0.00003686593	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Chatziioannou A	EnviroGenomarkers project consortium	28225026	2017-02-22	Tobacco smoking	EFO_0006527, EFO_0005671, EFO_0004318	-	Table S2	DNA methylation	Current vs never smoking	Age, sex, body mass index, study centre and cell counts	M values	-	Illumina HumanMethylation450	Whole blood	-	454	2	52	Both	None	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-	-	0.0000369	-	28225026_tobacco_smoking
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	-1.7	0.42	0.000037	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0340468	0.00825178	0.0000371185	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0355965	0.00862745	0.00003712227	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	0.0340401	0.00825179	0.000037248	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0399813	0.00969538	0.00003748074	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg21373811	chr14:103498437	14	103498437	CDC42BPB	Open sea	-0.129902	0.0315087	0.00003760363	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	-0.034016	0.00825179	0.00003772377	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	0.0033	0.00081	0.000038	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Battram T	GEO	23334450	2020-09-15	Rheumatoid arthritis	EFO_0000685	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE42861	None	DNA methylation	Rheumatoid arthritis	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	689	1	Adults	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.008	0.00193	0.000038	None	23334450_Battram-T_rheumatoid_arthritis_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse42861
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0558529	0.0135579	0.00003816508	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.033993	0.0082518	0.00003818331	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	-0.0422436	0.010256	0.00003827386	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.0339772	0.0082518	0.00003850222	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0360834	0.00876372	0.00003853434	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20521220	chr14:103442892	14	103442892	CDC42BPB	Open sea	0.0338842	0.00823393	0.0000388982	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Liver Cirrhosis	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Liver Cirrhosis	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18325	1	Adults (18-65y)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.016	0.00391	0.000039	None	Robert-F-Hillary_Incident_Liver_Cirrhosis_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0457351	0.0111191	0.0000392345	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.0345137	0.00839105	0.00003924057	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.033936	0.00825182	0.00003934423	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0376522	0.0091569	0.00003945616	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.0350759	0.00853623	0.00003994166	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0355237	0.00864576	0.00003998766	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age*sex	PATO_0000047,EFO_0000246	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	age*sex	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	-0.001	0.00025	0.00004	None	33450751_Mulder-RH_age_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	0.0338979	0.00825183	0.00004013857	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08999486	chr14:103523305	14	103523305	CDC42BPB	Island	0.0338749	0.00825183	0.0000406254	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20521220	chr14:103442892	14	103442892	CDC42BPB	Open sea	0.0339727	0.00827571	0.0000406303	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04569190	chr14:103422560	14	103422560	CDC42BPB	Open sea	-0.0024	0.00058	0.000041	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16334456	chr14:103436635	14	103436635	CDC42BPB	Open sea	0.013	0.0032	0.000041	None	33450751_Mulder-RH_sex_discovery
Lin Y	Patients recruited at The First Affiliated Hospital of Sun Yat-sen University	33319642	2021-07-01	IgA nephropathy	EFO_0004194, EFO_0003086, HP_0000112	None	Supplementary Table S1.EWAS	DNA methylation	IgA nephropathy	Age, Sex, Smoking, Cell composition (reference based), Batch effects	Beta Values	None	Illumina HumanMethylationEPIC	CD19+ B cells	ethnicity not reported but QC checks were made against 1000 Genomes Project EAS population	184	1	Adults	Both	East Asian	cg16716542	chr14:103453570	14	103453570	CDC42BPB	Open sea	-0.48	0.113	0.000041	None	33319642_Lin-Y_iga_nephropathy
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0419776	0.0102332	0.00004116301	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16058220	chr14:103490442	14	103490442	CDC42BPB	Open sea	0.180618	0.0440484	0.00004142508	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0555281	0.0135472	0.00004174415	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	0.0338217	0.00825185	0.00004177365	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0416255	0.0101562	0.00004179939	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0373294	0.00910834	0.00004183065	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0338149	0.00825185	0.00004192424	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0338141	0.00825185	0.00004194061	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CACNA2D3 protein levels (SeqId = 8885-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CACNA2D3 protein levels (SeqId = 8885-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Voltage-dependent calcium channel subunit alpha-2/delta-3	774	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.76	0.185	0.000042	None	Gadd-DA_cacna2d3_protein_levels__seqid___8885-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0338086	0.00825185	0.0000420618	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0338085	0.00825185	0.0000420652	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20220458	chr14:103500230	14	103500230	CDC42BPB	Open sea	0.0338005	0.00825185	0.00004224164	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0337945	0.00825186	0.00004237248	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	0.0353122	0.00862287	0.00004241111	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	0.033789	0.00825186	0.00004249599	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	-0.0337706	0.00825186	0.00004290582	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CXCL10 protein levels (SeqId = 4141-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXCL10 protein levels (SeqId = 4141-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-X-C motif chemokine 10	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.75	0.182	0.000043	None	Gadd-DA_cxcl10_protein_levels__seqid___4141-79__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ETHE1 protein levels (SeqId = 3847-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ETHE1 protein levels (SeqId = 3847-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Persulfide dioxygenase ETHE1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg06319903	chr14:103477661	14	103477661	CDC42BPB	Open sea	-0.5	0.121	0.000043	None	Gadd-DA_ethe1_protein_levels__seqid___3847-56__somascan_protein_measurement
Ligthart S	CHARGE	27955697	2016-12-12	C-reactive protein	EFO_0004458	Replication	Table S3	DNA methylation	C-reactive protein	Age, sex, smoking, body mass index, cell counts and technical covariates	Beta values	mg/l	Illumina HumanMethylation450	Whole blood	C-reactive protein levels were log-transformed	4111	4	59.7	Missing	African	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0051	0.001248	0.0000436	-	27955697_creactive_protein_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02938407	chr14:103486904	14	103486904	CDC42BPB	Open sea	0.0340482	0.0083311	0.00004395421	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21164005	chr14:103410594	14	103410594	CDC42BPB	South shelf	-0.0337163	0.00825188	0.0000441407	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0353292	0.00864715	0.00004418919	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	-0.0337049	0.00825188	0.00004440524	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0337047	0.00825188	0.00004440801	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0433941	0.0106285	0.00004472723	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.036	0.0088	0.000045	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0336758	0.00825189	0.00004508454	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02823212	chr14:103412128	14	103412128	CDC42BPB	Open sea	0.0336708	0.00825189	0.00004520132	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	0.0380346	0.0093217	0.00004523169	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0588536	0.0144247	0.00004526512	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19129605	chr14:103428549	14	103428549	CDC42BPB	North shore	-0.0336501	0.0082519	0.00004569207	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	0.0336466	0.0082519	0.000045775	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0352242	0.00864244	0.00004611354	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg26669125	chr14:103432390	14	103432390	CDC42BPB	South shore	-0.137533	0.0337487	0.00004618003	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	-0.0346421	0.00850084	0.00004623004	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.033621	0.0082519	0.00004638995	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21164005	chr14:103410594	14	103410594	CDC42BPB	South shelf	0.0429444	0.0105403	0.00004639702	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_4
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.900139	0.221	0.0000464	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01989521	chr14:103522012	14	103522012	CDC42BPB	North shore	-0.0336052	0.00825191	0.00004677142	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.033588	0.00825191	0.0000471933	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0389589	0.009573	0.00004732825	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.117574	0.028893	0.00004736819	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0335803	0.00825191	0.00004738177	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0335765	0.00825192	0.00004747609	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	-0.039665	0.00974895	0.00004753658	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0335705	0.00825192	0.00004762354	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	KIN protein levels (SeqId = 13476-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIN protein levels (SeqId = 13476-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA/RNA-binding protein KIN17	774	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.88	0.216	0.000048	None	Gadd-DA_kin_protein_levels__seqid___13476-16__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg19589358	chr14:103410516	14	103410516	CDC42BPB	South shelf	0.031	0.00767	0.000048	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0335539	0.00825192	0.00004803672	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0335506	0.00825192	0.00004812003	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	-0.0335438	0.00825193	0.00004828975	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	0.0369004	0.00908467	0.00004894282	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19589358	chr14:103410516	14	103410516	CDC42BPB	South shelf	0.0340577	0.00838563	0.00004902491	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21937244	chr14:103406412	14	103406412	CDC42BPB	Island	0.0335096	0.00825193	0.00004915544	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21373811	chr14:103498437	14	103498437	CDC42BPB	Open sea	-0.0335013	0.00825194	0.00004936861	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.0417681	0.0102895	0.00004947943	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0747632	0.0184208	0.00004961918	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0334833	0.00825194	0.00004983064	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.0744264	0.0183451	0.00004996122	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.0334779	0.00825194	0.00004997143	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0334732	0.00825194	0.00005009112	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_1
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	4.89e-05	1.21e-05	0.0000502	-	27843151_alcohol_consumption_per_day_african_ancestry
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19827	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P19827	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0556338	0.0137195	0.00005037767	P19827	41361833_Josephine_Robertson_P19827_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg14840966	chr14:103416389	14	103416389	CDC42BPB	Open sea	-0.218216	0.0538268	0.00005055168	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0334487	0.00825195	0.00005073266	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0576732	0.0142285	0.00005075131	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02938407	chr14:103486904	14	103486904	CDC42BPB	Open sea	0.0337732	0.00833234	0.00005076949	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0334423	0.00825195	0.00005090132	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02938407	chr14:103486904	14	103486904	CDC42BPB	Open sea	0.0029	None	0.000051	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26669125	chr14:103432390	14	103432390	CDC42BPB	South shore	0.0334224	0.00825196	0.00005142804	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.033419	0.00825196	0.00005151819	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Rheumatoid Arthritis (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Rheumatoid Arthritis (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14391	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.052	0.0128	0.000052	None	Robert-F-Hillary_Prevalent_Rheumatoid_Arthritis_(Self-report)_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P69905	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P69905	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0347434	0.00859182	0.00005286721	P69905	41361833_Josephine_Robertson_P69905_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0333608	0.00825198	0.00005309372	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0349224	0.00863878	0.00005315052	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0744205	0.0184186	0.00005360724	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0332947	0.00825199	0.00005493725	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0066	0.0016	0.000055	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	0.0332772	0.008252	0.0000554371	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	0.0340994	0.00845697	0.00005555806	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.0332646	0.008252	0.00005579906	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26405962	chr14:103432754	14	103432754	CDC42BPB	South shore	0.0332443	0.00825201	0.00005638644	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg27028800	chr14:103411330	14	103411330	CDC42BPB	Open sea	-0.227319	0.0564	0.0000565	None	27105112_hiv_infection_cd4_tcells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11754857	chr14:103447354	14	103447354	CDC42BPB	Open sea	-0.0332347	0.00825201	0.00005666627	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NAGPA protein levels (SeqId = 11208-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAGPA protein levels (SeqId = 11208-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.73	0.182	0.000057	None	Gadd-DA_nagpa_protein_levels__seqid___11208-15__somascan_protein_measurement
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg02855302	chr14:103453791	14	103453791	CDC42BPB	Open sea	-0.0638837	0.0158811	0.00005755	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0321832	0.00799884	0.00005763109	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16334456	chr14:103436635	14	103436635	CDC42BPB	Open sea	-0.0331995	0.00825202	0.00005770279	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	0.0331942	0.00825202	0.00005785867	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-0.0322583	0.00801952	0.00005787933	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.087	0.0217	0.000058	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.288366	0.0717	0.0000584	None	27105112_hiv_infection_cd4_tcells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0331595	0.00825203	0.00005890176	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.0331262	0.00825204	0.00005991782	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18505004	chr14:103436387	14	103436387	CDC42BPB	Open sea	0.0339552	0.00846464	0.00006065414	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-0.0334767	0.00834577	0.00006070765	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0330951	0.00825205	0.00006088326	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GRID2 protein levels (SeqId = 12758-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRID2 protein levels (SeqId = 12758-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutamate receptor ionotropic, delta-2	774	1	Adults (18-65 years)	Both	European	cg14533120	chr14:103447664	14	103447664	CDC42BPB	Open sea	0.549	0.137	0.000061	None	Gadd-DA_grid2_protein_levels__seqid___12758-47__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0349361	0.0087137	0.0000611915	P00748	41361833_Josephine_Robertson_P00748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18588794	chr14:103467739	14	103467739	CDC42BPB	Open sea	0.0330838	0.00825205	0.000061237	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0414144	0.0103351	0.00006175791	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Lung Cancer	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Lung Cancer	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18364	1	Adults (18-65y)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.021	0.00534	0.000062	None	Robert-F-Hillary_Incident_Lung_Cancer_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0579108	0.0144567	0.00006211217	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0580535	0.0144936	0.0000622039	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Chronic Pain	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Chronic Pain	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	11591	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.045	0.0113	0.000063	None	Robert-F-Hillary_Incident_Chronic_Pain_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0330166	0.00825207	0.00006338317	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0380034	0.00950172	0.00006375109	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	0.0330048	0.00825207	0.00006376555	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-	-	0.0000638	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0392545	0.00981737	0.00006406534	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.034314	0.00858725	0.00006475899	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	0.032942	0.00825209	0.00006584775	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0577105	0.0144571	0.00006587829	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0115	0.0029	0.000066	-	27651444_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14003974	chr14:103497991	14	103497991	CDC42BPB	Open sea	-0.0329343	0.00825209	0.00006610841	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.109131	0.0274	0.0000663	-	27105112_hiv_infection_neutrophils
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0314035	0.00787053	0.00006639136	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0345144	0.00865228	0.00006665913	P00748	41361833_Josephine_Robertson_P00748_OSCA_model_2
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.002	0.00049	0.000067	None	33564054_Kashima-K_gestational_age
Battram T	ARIES	None	2020-08-20	Total cholesterol in very large VLDL	EFO_0004574	None	None	DNA methylation	Total cholesterol in very large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	646	1	Adults	Females	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	15.3	3.8	0.000067	None	Battram-T_total_cholesterol_in_very_large_vldl
Gadd DA	Generation Scotland	35945220	31/07/2022	ADH1B protein levels (SeqId = 9834-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADH1B protein levels (SeqId = 9834-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alcohol dehydrogenase 1B	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.73	0.182	0.000067	None	Gadd-DA_adh1b_protein_levels__seqid___9834-62__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12253258	chr14:103494823	14	103494823	CDC42BPB	Open sea	-0.032892	0.0082521	0.00006755347	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.0328878	0.00825211	0.00006769817	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMK protein levels (SeqId = 9545-156)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMK protein levels (SeqId = 9545-156)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme K	774	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.86	0.216	0.000068	None	Gadd-DA_gzmk_protein_levels__seqid___9545-156__somascan_protein_measurement
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	2.93e-05	7.35e-06	0.0000681	-	27843151_alcohol_consumption_per_day_african_ancestry
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21086153	chr14:103519032	14	103519032	CDC42BPB	North shelf	-0.0328756	0.00825211	0.00006811867	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0439635	0.0110396	0.00006856522	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.0054	0.0014	0.000069	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	0.0432319	0.0108616	0.00006917855	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0328413	0.00825212	0.00006932305	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0394476	0.00991596	0.00006977453	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	CXCL10 protein levels (SeqId = 4141-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXCL10 protein levels (SeqId = 4141-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-X-C motif chemokine 10	774	1	Adults (18-65 years)	Both	European	cg26103168	chr14:103507914	14	103507914	CDC42BPB	Open sea	-0.29	0.072	0.00007	None	Gadd-DA_cxcl10_protein_levels__seqid___4141-79__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0344022	0.00865565	0.0000708543	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04430	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04430	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0327883	0.00825213	0.00007121985	P04430	41361833_Josephine_Robertson_P04430_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0342888	0.00862988	0.00007123345	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.251841	0.0633903	0.00007130233	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0327729	0.00825214	0.00007177777	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CNTN5 protein levels (SeqId = 3299-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CNTN5 protein levels (SeqId = 3299-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Contactin-5	774	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.5	0.125	0.000072	None	Gadd-DA_cntn5_protein_levels__seqid___3299-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	0.0327552	0.00825214	0.00007242888	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	-0.032745	0.00825214	0.00007280438	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0341164	0.0086	0.0000731227	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	-0.0327317	0.00825215	0.00007329997	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0534234	0.0134692	0.00007333573	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0327257	0.00825215	0.00007352421	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0578596	0.0145901	0.00007353316	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CCL7 protein levels (SeqId = 4886-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCL7 protein levels (SeqId = 4886-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-C motif chemokine 7	774	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.42	0.106	0.000074	None	Gadd-DA_ccl7_protein_levels__seqid___4886-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IGLL1 protein levels (SeqId = 6485-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IGLL1 protein levels (SeqId = 6485-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin lambda-like polypeptide 1	774	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.42	0.106	0.000074	None	Gadd-DA_igll1_protein_levels__seqid___6485-59__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0327043	0.00825215	0.00007432802	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0341669	0.00862538	0.00007492418	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0326668	0.00825216	0.00007575313	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12721857	chr14:103494686	14	103494686	CDC42BPB	Open sea	0.0326657	0.00825217	0.00007579517	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13971	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.028	0.00718	0.000076	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Fully-adjusted_model
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21231141	chr14:103411005	14	103411005	CDC42BPB	Open sea	-0.01062	0.00263	0.000076	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	-0.0326531	0.00825217	0.00007628127	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q16610	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q16610	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0326416	0.00825217	0.00007672701	Q16610	41361833_Josephine_Robertson_Q16610_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SEMA4B protein levels (SeqId = 9805-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SEMA4B protein levels (SeqId = 9805-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Semaphorin-4B	774	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.73	0.185	0.000077	None	Gadd-DA_sema4b_protein_levels__seqid___9805-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HP protein levels (SeqId = 7905-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HP protein levels (SeqId = 7905-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Haptoglobin	774	1	Adults (18-65 years)	Both	European	cg15827779	chr14:103524899	14	103524899	CDC42BPB	South shore	0.41	0.104	0.000077	None	Gadd-DA_hp_protein_levels__seqid___7905-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXNB2 protein levels (SeqId = 9216-100)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXNB2 protein levels (SeqId = 9216-100)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-B2	774	1	Adults (18-65 years)	Both	European	cg26403748	chr14:103406333	14	103406333	CDC42BPB	Island	-0.82	0.208	0.000077	None	Gadd-DA_plxnb2_protein_levels__seqid___9216-100__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26669125	chr14:103432390	14	103432390	CDC42BPB	South shore	-0.032633	0.00825217	0.00007706576	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	-0.034452	0.00871245	0.00007710588	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0379708	0.00960324	0.000077232	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0326227	0.00825218	0.00007746612	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	-0.0335893	0.00850178	0.00007823942	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0428804	0.0108572	0.00007868598	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	0.0325848	0.00825219	0.00007896723	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	IL22RA2 protein levels (SeqId = 5087-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL22RA2 protein levels (SeqId = 5087-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-22 receptor subunit alpha-2	774	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.42	0.106	0.000079	None	Gadd-DA_il22ra2_protein_levels__seqid___5087-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PTK7 protein levels (SeqId = 9525-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTK7 protein levels (SeqId = 9525-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inactive tyrosine-protein kinase 7	774	1	Adults (18-65 years)	Both	European	cg26403748	chr14:103406333	14	103406333	CDC42BPB	Island	-0.82	0.207	0.000079	None	Gadd-DA_ptk7_protein_levels__seqid___9525-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	0.0325719	0.00825219	0.00007948563	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0382392	0.00968861	0.00007956419	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_2
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	malathion	CHEBI_6651	discovery	10.5281/zenodo.5156585	DNA methylation	malathion	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	232	1	Adults	Males	European	cg04189326	chr14:103481271	14	103481271	CDC42BPB	Open sea	0.02174	0.0055	0.00008	None	34516295_Hoang_malathion_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0418691	0.0106146	0.00008034394	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_4
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg04569190	chr14:103422560	14	103422560	CDC42BPB	Open sea	-0.855039	0.2169	0.0000806	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0427502	0.010843	0.00008095933	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00848479	chr14:103399852	14	103399852	CDC42BPB	South shelf	-0.0390128	0.00989678	0.00008119161	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13800228	chr14:103412853	14	103412853	CDC42BPB	Open sea	0.0325272	0.0082522	0.00008130111	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Liver Cirrhosis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Liver Cirrhosis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14358	1	Adults (18-65y)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.0067	0.00171	0.000082	None	Robert-F-Hillary_Incident_Liver_Cirrhosis_Fully-adjusted_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	-0.00048	0.00012	0.000082	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0573246	0.0145538	0.00008226586	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	AGAP3 protein levels (SeqId = 13960-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AGAP3 protein levels (SeqId = 13960-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3	774	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.85	0.216	0.000083	None	Gadd-DA_agap3_protein_levels__seqid___13960-15__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	-0.0096	0.0024	0.000083	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02907662	chr14:103432714	14	103432714	CDC42BPB	South shore	-0.0346765	0.00880931	0.00008311489	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	-0.0324805	0.00825222	0.00008324122	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0324795	0.00825222	0.00008328436	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04899282	chr14:103523516	14	103523516	CDC42BPB	Island	-0.0364319	0.00925928	0.0000837069	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22897701	chr14:103432870	14	103432870	CDC42BPB	South shelf	0.0324664	0.00825222	0.00008383782	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26669125	chr14:103432390	14	103432390	CDC42BPB	South shore	-0.0324646	0.00825222	0.00008391117	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CBLN4 protein levels (SeqId = 5688-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBLN4 protein levels (SeqId = 5688-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cerebellin-4	774	1	Adults (18-65 years)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.73	0.185	0.000084	None	Gadd-DA_cbln4_protein_levels__seqid___5688-65__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0061	0.0016	0.000084	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg01306540	chr14:103432476	14	103432476	CDC42BPB	South shore	-0.037	0.00944	0.000084	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21373811	chr14:103498437	14	103498437	CDC42BPB	Open sea	-0.0325903	0.00828684	0.00008435546	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15888803	chr14:103443124	14	103443124	CDC42BPB	Open sea	-0.225701	0.0573955	0.00008443754	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.0325222	0.00827282	0.00008490534	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17483	1	Adults (18-65y)	Both	European	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	0.034	0.00868	0.000085	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	HP protein levels (SeqId = 7905-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HP protein levels (SeqId = 7905-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Haptoglobin	774	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.37	0.093	0.000085	None	Gadd-DA_hp_protein_levels__seqid___7905-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IFNA16 protein levels (SeqId = 6421-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFNA16 protein levels (SeqId = 6421-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon alpha-16	774	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	-0.87	0.221	0.000085	None	Gadd-DA_ifna16_protein_levels__seqid___6421-52__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	0.03677	0.00935841	0.00008566039	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	SRGN protein levels (SeqId = 19251-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SRGN protein levels (SeqId = 19251-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serglycin	774	1	Adults (18-65 years)	Both	European	cg20521220	chr14:103442892	14	103442892	CDC42BPB	Open sea	0.83	0.211	0.000086	None	Gadd-DA_srgn_protein_levels__seqid___19251-56__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07561535	chr14:103442719	14	103442719	CDC42BPB	Open sea	-0.0324156	0.00825223	0.00008601182	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15622519	chr14:103468278	14	103468278	CDC42BPB	Open sea	0.0326671	0.00831868	0.0000864229	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07652906	chr14:103430858	14	103430858	CDC42BPB	South shore	0.0323882	0.00825224	0.00008720679	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15988734	chr14:103411822	14	103411822	CDC42BPB	Open sea	0.00073	None	0.000088	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg06901584	chr14:103399713	14	103399713	CDC42BPB	South shelf	0.22	0.0565	0.000088	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18211157	chr14:103469613	14	103469613	CDC42BPB	Open sea	-0.0323697	0.00825224	0.0000880233	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10036612	chr14:103410963	14	103410963	CDC42BPB	Open sea	-0.032355	0.00825225	0.0000886745	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	-0.0376358	0.00959992	0.00008879541	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	0.005	0.0013	0.000089	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	-0.0327448	0.0083574	0.0000896671	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	NTRK2 protein levels (SeqId = 4866-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NTRK2 protein levels (SeqId = 4866-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BDNF/NT-3 growth factors receptor	774	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.49	0.125	0.00009	None	Gadd-DA_ntrk2_protein_levels__seqid___4866-59__somascan_protein_measurement
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	-0.0036	0.00089	0.00009	None	33564054_Kashima-K_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04919519	chr14:103524989	14	103524989	CDC42BPB	South shore	0.0323244	0.00825226	0.00009004993	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00006899	chr14:103483021	14	103483021	CDC42BPB	Open sea	-0.0425274	0.0108583	0.00009021466	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0330748	0.00844513	0.0000902742	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	0.0358923	0.00916486	0.0000903288	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18790649	chr14:103399833	14	103399833	CDC42BPB	South shelf	0.0326578	0.00833928	0.00009038313	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19589358	chr14:103410516	14	103410516	CDC42BPB	South shelf	0.0326448	0.00833701	0.00009056987	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Free cholesterol in chylomicrons and extremely large VLDL	EFO_0008591	None	None	DNA methylation	Free cholesterol in chylomicrons and extremely large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	645	1	Adults	Females	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	96	24	0.000091	None	Battram-T_free_cholesterol_in_chylomicrons_and_extremely_large_vldl
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.0871916	0.0222833	0.00009155525	None	39706196_Hannah-M.-Smith_bmi_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJC18 protein levels (SeqId = 8033-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJC18 protein levels (SeqId = 8033-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily C member 18	774	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.85	0.216	0.000092	None	Gadd-DA_dnajc18_protein_levels__seqid___8033-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0322808	0.00825227	0.00009204199	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04899282	chr14:103523516	14	103523516	CDC42BPB	Island	0.0360905	0.00923259	0.00009308168	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CFAP45 protein levels (SeqId = 6553-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CFAP45 protein levels (SeqId = 6553-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cilia- and flagella-associated protein 45	774	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.42	0.106	0.000094	None	Gadd-DA_cfap45_protein_levels__seqid___6553-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CA5B protein levels (SeqId = 17673-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CA5B protein levels (SeqId = 17673-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carbonic anhydrase 5B, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg26103168	chr14:103507914	14	103507914	CDC42BPB	Open sea	-0.28	0.072	0.000094	None	Gadd-DA_ca5b_protein_levels__seqid___17673-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EPHA5 protein levels (SeqId = 3806-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPHA5 protein levels (SeqId = 3806-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ephrin type-A receptor 5	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.71	0.182	0.000094	None	Gadd-DA_epha5_protein_levels__seqid___3806-55__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04715649	chr14:103416122	14	103416122	CDC42BPB	Open sea	-0.0322206	0.00825228	0.00009486522	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NBL1 protein levels (SeqId = 2944-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NBL1 protein levels (SeqId = 2944-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Neuroblastoma suppressor of tumorigenicity 1	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.71	0.182	0.000095	None	Gadd-DA_nbl1_protein_levels__seqid___2944-66__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19782190	chr14:103487004	14	103487004	CDC42BPB	Open sea	-0.0386422	0.00989834	0.00009507584	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04899282	chr14:103523516	14	103523516	CDC42BPB	Island	-0.0515856	0.0132141	0.00009511232	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	0.0337323	0.00864198	0.00009531072	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14543730	chr14:103410161	14	103410161	CDC42BPB	South shelf	0.0038	None	0.000096	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	KLK11 protein levels (SeqId = 2831-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLK11 protein levels (SeqId = 2831-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kallikrein-11	774	1	Adults (18-65 years)	Both	European	cg03169691	chr14:103452012	14	103452012	CDC42BPB	Open sea	0.711	0.182	0.000096	None	Gadd-DA_klk11_protein_levels__seqid___2831-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	0.0563987	0.0144586	0.0000963477	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg02855302	chr14:103453791	14	103453791	CDC42BPB	Open sea	-0.146379	0.0375304	0.00009642558	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	0.038	0.00987	0.000097	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Battram T	ARIES	None	2020-08-20	Triglycerides in chylomicrons and extremely large VLDL	EFO_0004530	None	None	DNA methylation	Triglycerides in chylomicrons and extremely large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	654	1	Adults	Females	European	cg13164814	chr14:103468473	14	103468473	CDC42BPB	Open sea	12.2	3.1	0.000097	None	Battram-T_triglycerides_in_chylomicrons_and_extremely_large_vldl
Gadd DA	Generation Scotland	35945220	31/07/2022	HRASLS2 protein levels (SeqId = 7822-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HRASLS2 protein levels (SeqId = 7822-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: HRAS-like suppressor 2	774	1	Adults (18-65 years)	Both	European	cg20043258	chr14:103468582	14	103468582	CDC42BPB	Open sea	0.41	0.106	0.000097	None	Gadd-DA_hrasls2_protein_levels__seqid___7822-11__somascan_protein_measurement
Carmona JJ	Normative Aging Study	30343628	2018-10-21	Lung function decline	EFO_0004312, EFO_0003892	Discovery. FVC. Lung function decline in this paper is defined as a decrease in FVC between visits.	Table S1	Lung function decline	DNA methylation	Season, follow up time, batch effects, weight, weight squared, log(height), age, vitamin C intake, years of education, taking corticosteroids or beta-2-adrenergic agonists or AHFS or LAMA, smoking	L	Beta Values	Illumina HumanMethylation450	Whole blood	None	633	1	Adults	Males	European	cg14474150	chr14:103433374	14	103433374	CDC42BPB	South shelf	-0.929	0.2385	0.000098	None	30343628_Carmona-JJ_lung_function_decline_discovery__fvc__lung_function_decline_in_this_paper_is_defined_as_a_decrease_in_fvc_between_visits_
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21057323	chr14:103412980	14	103412980	CDC42BPB	Open sea	-0.0567929	0.0145791	0.00009843416	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	-0.0334303	0.00858229	0.000098529	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02938407	chr14:103486904	14	103486904	CDC42BPB	Open sea	0.042683	0.0109596	0.00009881372	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	UTS2R protein levels (SeqId = 13530-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UTS2R protein levels (SeqId = 13530-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Urotensin-2 receptor	774	1	Adults (18-65 years)	Both	European	cg11384750	chr14:103430786	14	103430786	CDC42BPB	Island	-0.84	0.216	0.000099	None	Gadd-DA_uts2r_protein_levels__seqid___13530-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09262100	chr14:103416268	14	103416268	CDC42BPB	Open sea	0.0321342	0.00825231	0.00009905354	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09605038	chr14:103465628	14	103465628	CDC42BPB	Open sea	0.0321289	0.00825231	0.00009931989	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24779941	chr14:103524901	14	103524901	CDC42BPB	South shore	-0.0328458	0.00843772	0.00009955688	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2