author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18328428	chr5:10291212	5	10291212	CMBL	Open sea	-0.0024	0.00016	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22566694	chr5:10309123	5	10309123	CMBL	South shore	-0.0024	0.00023	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg22566694	chr5:10309123	5	10309123	CMBL	South shore	0.24002	0.00634	2.8e-91	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.04555	0.00174	1.4e-65	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	2.42609	0.0674	4.92e-54	-	25282492_fetal_vs_adult_liver
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08332662	chr5:10284254	5	10284254	CMBL	Open sea	-0.16078	0.0076	3.5e-52	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	2.29564	0.07989	3.54e-46	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg01879083	chr5:10306031	5	10306031	CMBL	North shore	2.98854	0.10412	3.85e-46	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg23284609	chr5:10306947	5	10306947	CMBL	North shore	2.46187	0.11147	1.98e-37	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.1044	0.00821145	7.739881e-37	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0990342	0.00821598	2.6594740000000002e-33	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.00048	None	2e-27	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg00123333	chr5:10291242	5	10291242	CMBL	Open sea	-0.0207	0.00164	6.1e-27	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.0766112	0.00823231	1.5096089999999998e-20	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	-0.0749381	0.00823336	1.0013109999999999e-19	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0744813	0.00823364	1.666545e-19	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0741094	0.00823387	2.51725e-19	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.0738309	0.00823404	3.423622e-19	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	0.0738235	0.00823404	3.4516609999999997e-19	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.069	0.00664	1.8e-17	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	0.0698883	0.00823638	2.355103e-17	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	0.0693616	0.00823669	4.0737530000000005e-17	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg26878318	chr5:10308785	5	10308785	CMBL	South shore	-3.40567	0.4115	1.26e-16	-	27105112_hiv_infection_discovery
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.2236	0.027	1.38e-16	-	25650246_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	PRG3 protein levels (SeqId = 9015-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRG3 protein levels (SeqId = 9015-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteoglycan 3	774	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-1.67	0.202	1.7e-16	None	Gadd-DA_prg3_protein_levels__seqid___9015-1__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04990989	chr5:10291308	5	10291308	CMBL	Open sea	-0.00043	0.000053	6.7e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.055	0.00571	8.2e-16	None	32795589_Kyung-WK_eosinophilia_discovery
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.2463	0.0308	0.00000000000000141	-	25650246_gestational_age
Battram T	GEO	25282492	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE61278. Compared fetal liver tissue to adult liver tissue of different individuals	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Fetal liver, adult liver	None	110	1	Adults	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.672	0.07	0.000000000000002	None	25282492_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse61278__compared_fetal_liver_tissue_to_adult_liver_tissue_of_different_individuals
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17326974	chr5:10290391	5	10290391	CMBL	Open sea	0.0649345	0.00823915	0.000000000000003468908	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.01709	0.0022	0.00000000000000521	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.063949	0.00823967	0.000000000000008972365	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg11882252	chr5:10307634	5	10307634	CMBL	Island	0.01239	0.00148	0.000000000000011	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.0636298	0.00823984	0.00000000000001216915	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.01601	0.0021	0.0000000000000162	-	23334450_rheumatoid_arthritis
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPPA protein levels (SeqId = 4148-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPPA protein levels (SeqId = 4148-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pappalysin-1	774	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-1.53	0.201	0.000000000000031	None	Gadd-DA_pappa_protein_levels__seqid___4148-49__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.226571	0.0301084	0.00000000000005522675	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	0.060899	0.00824125	0.000000000000155286	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	0.0606844	0.00824135	0.0000000000001888123	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05593349	chr5:10307744	5	10307744	CMBL	Island	0.00663	0.00084	0.00000000000028	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2848265 (gene symbol: CMBL)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2848265 (gene symbol: CMBL)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg08332662	chr5:10284254	5	10284254	CMBL	Open sea	None	None	0.00000000000045	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2848265__gene_symbol__cmbl__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.05915	0.00824212	0.00000000000074915	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.036	0.0044	0.0000000000011	None	32795589_Kyung-WK_atopy_discovery
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg11882252	chr5:10307634	5	10307634	CMBL	Island	0.01329	0.0019	0.00000000000135	-	23334450_rheumatoid_arthritis
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg05593349	chr5:10307744	5	10307744	CMBL	Island	1.768438	0.2498	0.00000000000144	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.058066	0.00824264	0.000000000001942955	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	0.0562396	0.0082435	0.000000000009310688	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	-0.056147	0.00824355	0.00000000001006726	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.0557449	0.00824373	0.00000000001411481	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.0555782	0.00824381	0.00000000001622613	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.00034	0.000051	0.000000000023	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	0.0551452	0.00824401	0.00000000002326426	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.0550613	0.00824405	0.00000000002493808	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00123333	chr5:10291242	5	10291242	CMBL	Open sea	0.0011	None	0.000000000025	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.0137	0.0021	0.0000000000292	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0548427	0.00824415	0.00000000002987361	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.00067	0.0001	0.000000000034	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.0546229	0.00824424	0.00000000003579358	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.0636616	0.00972654	0.00000000006141454	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Battram T	GEO	25282492	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE61278. Compared fetal liver tissue to adult liver tissue of different individuals	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Fetal liver, adult liver	None	110	1	Adults	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.615	0.083	0.00000000007	None	25282492_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse61278__compared_fetal_liver_tissue_to_adult_liver_tissue_of_different_individuals
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.196966	0.0301895	0.00000000007020321	None	39706196_Hannah-M.-Smith_body_fat_discovery
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg13323825	chr5:10307831	5	10307831	CMBL	Island	1.892008	0.2944	0.00000000013	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	0.0527514	0.00824508	0.000000000162283	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0525619	0.00824516	0.0000000001885789	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.0014	None	0.00000000022	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Christiansen C	TwinsUK, NSHD, NCDS1, NCDS2, BCS70	33593402	2021-02-16	Smoking	EFO_0004318, EFO_0006527	Current vs never smoking meta-analysis in European samples	Table S1	DNA methylation	Smoking	Sex, cell composition (reference based), body mass index, batch effects, relatedness	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	912	5	Adults	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	None	None	0.00000000036	None	33593402_Christiansen-C_smoking_current_vs_never_smoking_meta-analysis_in_european_samples
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16724323	chr5:10291965	5	10291965	CMBL	Open sea	-0.0516179	0.00824556	0.0000000003954779	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.02573	0.00397	0.00000000071	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.0507743	0.00824592	0.0000000007582529	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0506955	0.00824595	0.0000000008053712	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.0502394	0.00824615	0.000000001139613	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	0.0496323	0.0082464	0.000000001800474	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.041	0.00691	0.0000000022	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	-0.0490537	0.00824663	0.000000002770615	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16724323	chr5:10291965	5	10291965	CMBL	Open sea	-0.0489562	0.00824667	0.000000002977856	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.0484348	0.00824688	0.000000004369562	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0640273	0.0109145	0.000000004553286	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	0.0477081	0.00824717	0.000000007408711	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.047585	0.00824722	0.000000008095378	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.0474233	0.00824728	0.000000009092846	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.00023082	4.02e-05	0.0000000119	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	PRG2 protein levels (SeqId = 7258-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRG2 protein levels (SeqId = 7258-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bone marrow proteoglycan	774	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-1.15	0.202	0.000000012	None	Gadd-DA_prg2_protein_levels__seqid___7258-5__somascan_protein_measurement
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	4.3	0.754	0.000000016	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0500648	0.00892263	0.00000002048106	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.0539765	0.00972742	0.00000002924597	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17326974	chr5:10290391	5	10290391	CMBL	Open sea	0.0456757	0.00824795	0.00000003115097	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	0.0455855	0.00824799	0.00000003315628	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0494897	0.00899936	0.00000003877919	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.0451803	0.00824814	0.00000004381402	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0481111	0.00880669	0.00000004757584	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0450236	0.0082482	0.00000004876955	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.0446006	0.00824836	0.00000006501635	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02628107	chr5:10279354	5	10279354	CMBL	Open sea	0.00093	None	0.00000008	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.0441933	0.0082485	0.00000008554185	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.0439719	0.00824859	0.00000009920523	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	0.0438555	0.00824863	0.0000001072148	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00123333	chr5:10291242	5	10291242	CMBL	Open sea	0.0438295	0.00824864	0.0000001090889	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.043812	0.00824864	0.0000001103663	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	-0.0437418	0.00824867	0.0000001156333	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	-0.0432826	0.00824883	0.0000001566441	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.027	0.00521	0.00000017	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	-0.0431521	0.00824888	0.0000001706698	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0560489	0.0107175	0.000000172163	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Cardenas A	Project Viva	31300640	Jul 12, 2019	fractional exhaled nitric oxide (FeNO)	EFO_0005536	None	Supplementary Data 2	DNA methylation	fractional exhaled nitric oxide (FeNO)	Age, Sex, Smoking, Cell composition (reference free), Batch effects, Ancestry (other), Body mass index, Education, sine and cosine of season at sample collection	Beta values	ppb	Illumina HumanMethylationEPIC	nasal epithelium	None	517	1	Children	Both	Other	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-3.15	0.6	0.00000022	SE manually calculated	31300640_Cardenas-A_fractional_exhaled_nitric_oxide__feno_
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.0427581	0.00824902	0.0000002207502	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	-0.0424761	0.00824912	0.0000002650271	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	1.4	0.274	0.00000031	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	STX1A protein levels (SeqId = 19553-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STX1A protein levels (SeqId = 19553-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Syntaxin-1A	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.488	0.096	0.00000036	None	Gadd-DA_stx1a_protein_levels__seqid___19553-14__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.041949	0.0082493	0.0000003718571	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.041947	0.0082493	0.0000003723148	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.0418175	0.00824935	0.0000004043802	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0451623	0.00895474	0.0000004628156	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Carmona JJ	Normative Aging Study	30343628	2018-10-21	Lung function decline	EFO_0004314, EFO_0003892	Discovery. FEV1. Lung function decline in this paper is defined as a decrease in FEV1 between visits.	Table S1	Lung function decline	DNA methylation	Season, follow up time, batch effects, weight, weight squared, log(height), age, vitamin C intake, years of education, taking corticosteroids or beta-2-adrenergic agonists or AHFS or LAMA, smoking	L/s	Beta Values	Illumina HumanMethylation450	Whole blood	None	633	1	Adults	Males	European	cg05593349	chr5:10307744	5	10307744	CMBL	Island	0.433	0.0865	0.00000054	None	30343628_Carmona-JJ_lung_function_decline_discovery__fev1__lung_function_decline_in_this_paper_is_defined_as_a_decrease_in_fev1_between_visits_
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	0.0412341	0.00824955	0.0000005849213	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18328428	chr5:10291212	5	10291212	CMBL	Open sea	-0.01541	0.00299	0.00000061	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	-0.0411652	0.00824957	0.0000006107729	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.0407917	0.0082497	0.0000007713056	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16724323	chr5:10291965	5	10291965	CMBL	Open sea	-0.0407013	0.00824973	0.0000008159274	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18328428	chr5:10291212	5	10291212	CMBL	Open sea	0.0403102	0.00824986	0.000001039022	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0434124	0.00894864	0.000001239245	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0399757	0.00824997	0.000001275459	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13323825	chr5:10307831	5	10307831	CMBL	Island	0.00692	0.00139	0.0000013	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	NXT1 protein levels (SeqId = 9942-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NXT1 protein levels (SeqId = 9942-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NTF2-related export protein 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.46	0.096	0.0000013	None	Gadd-DA_nxt1_protein_levels__seqid___9942-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0399035	0.00825	0.000001332906	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	0.039832	0.00825002	0.000001392266	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0397865	0.00825003	0.000001431274	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	-0.152891	0.0317209	0.000001448764	None	39706196_Hannah-M.-Smith_bmi_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.0035	0.00072	0.0000016	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.0395631	0.00825011	0.0000016389	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01879083	chr5:10306031	5	10306031	CMBL	North shore	0.00057	None	0.0000017	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.0394257	0.00825015	0.000001780684	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.0463057	0.0097046	0.000001845994	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg17209231	chr5:10308666	5	10308666	CMBL	South shore	-1.372413	0.2885	0.00000196	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00123333	chr5:10291242	5	10291242	CMBL	Open sea	0.0390979	0.00825026	0.000002167974	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0512557	0.0108334	0.000002251999	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.0390007	0.00825029	0.00000229768	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0417561	0.00884178	0.000002350156	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	0.0389355	0.00825031	0.000002388642	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	0.0389246	0.00825031	0.000002404234	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	-0.0387559	0.00825037	0.000002657927	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	-0.0387076	0.00825038	0.000002735061	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.0385902	0.00825042	0.000002931822	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16724323	chr5:10291965	5	10291965	CMBL	Open sea	0.0385879	0.00825042	0.00000293583	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	0.0379214	0.00825063	0.000004339033	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	0.0379152	0.00825063	0.000004354727	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	0.037877	0.00825065	0.000004452399	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.028	0.00613	0.0000045	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	0.037818	0.00825067	0.000004607432	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	0.0377507	0.00825069	0.000004790729	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PRSS57 protein levels (SeqId = 8351-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRSS57 protein levels (SeqId = 8351-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine protease 57	774	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.93	0.202	0.0000048	None	Gadd-DA_prss57_protein_levels__seqid___8351-17__somascan_protein_measurement
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.00021117	4.59e-05	0.00000481	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	VCL protein levels (SeqId = 8750-46)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VCL protein levels (SeqId = 8750-46)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vinculin	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.436	0.095	0.000005	None	Gadd-DA_vcl_protein_levels__seqid___8750-46__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	0.0376278	0.00825072	0.000005143548	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.0477134	0.0105079	0.000005650426	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23284609	chr5:10306947	5	10306947	CMBL	North shore	-0.0374264	0.00825079	0.000005775866	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	-0.0374169	0.00825079	0.000005807352	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.0373778	0.0082508	0.000005939231	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	HSPH1 protein levels (SeqId = 17704-74)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSPH1 protein levels (SeqId = 17704-74)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heat shock protein 105 kDa	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.43	0.095	0.0000061	None	Gadd-DA_hsph1_protein_levels__seqid___17704-74__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.0471672	0.0104675	0.000006655649	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	0.0371719	0.00825087	0.000006681751	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	BAG1 protein levels (SeqId = 17195-43)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BAG1 protein levels (SeqId = 17195-43)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BAG family molecular chaperone regulator 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.43	0.095	0.0000068	None	Gadd-DA_bag1_protein_levels__seqid___17195-43__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16724323	chr5:10291965	5	10291965	CMBL	Open sea	-0.0370927	0.00825089	0.000006990515	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	-0.168805	0.0376035	0.000007199277	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	-0.0370323	0.00825091	0.000007235017	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0369842	0.00825092	0.000007435471	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg00753835	chr5:10289616	5	10289616	CMBL	Open sea	-0.1697	0.0379398	0.000007763866	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17326974	chr5:10290391	5	10290391	CMBL	Open sea	0.0368697	0.00825096	0.000007934582	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	0.036825	0.00825097	0.000008138074	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	APEX1 protein levels (SeqId = 9849-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APEX1 protein levels (SeqId = 9849-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA-(apurinic or apyrimidinic site) lyase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.43	0.096	0.0000086	None	Gadd-DA_apex1_protein_levels__seqid___9849-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KLC1 protein levels (SeqId = 12656-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLC1 protein levels (SeqId = 12656-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kinesin light chain 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.42	0.095	0.0000087	None	Gadd-DA_klc1_protein_levels__seqid___12656-1__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05593349	chr5:10307744	5	10307744	CMBL	Island	0.000062	None	0.0000088	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	-0.0366835	0.00825101	0.000008815323	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	0.0365601	0.00825105	0.000009449437	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.0365523	0.00825105	0.000009490685	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CPNE1 protein levels (SeqId = 5346-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CPNE1 protein levels (SeqId = 5346-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Copine-1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.42	0.096	0.0000096	None	Gadd-DA_cpne1_protein_levels__seqid___5346-24__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.036472	0.00825108	0.000009928779	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	3.6	0.814	0.00001	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	S100A6 protein levels (SeqId = 13090-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	S100A6 protein levels (SeqId = 13090-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein S100-A6	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.42	0.096	0.00001	None	Gadd-DA_s100a6_protein_levels__seqid___13090-17__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0394238	0.00894966	0.00001065048	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13323825	chr5:10307831	5	10307831	CMBL	Island	0.0362542	0.00827009	0.00001174518	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0361069	0.00825119	0.000012173	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0360916	0.00825119	0.00001227697	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23284609	chr5:10306947	5	10306947	CMBL	North shore	-0.0360828	0.00825119	0.00001233705	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	0.0400571	0.00918896	0.00001313883	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	0.035946	0.00825124	0.00001330946	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13323825	chr5:10307831	5	10307831	CMBL	Island	0.0360209	0.00827764	0.00001360708	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	-0.0358659	0.00825126	0.00001391226	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17111521	chr5:10309042	5	10309042	CMBL	South shore	0.0364749	0.00841857	0.00001482883	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	SMC3 protein levels (SeqId = 14324-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMC3 protein levels (SeqId = 14324-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Structural maintenance of chromosomes protein 3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.41	0.096	0.000015	None	Gadd-DA_smc3_protein_levels__seqid___14324-52__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23284609	chr5:10306947	5	10306947	CMBL	North shore	-0.0356393	0.00825133	0.0000157609	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SUMO3 protein levels (SeqId = 14623-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUMO3 protein levels (SeqId = 14623-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Small ubiquitin-related modifier 3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.41	0.095	0.000016	None	Gadd-DA_sumo3_protein_levels__seqid___14623-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDX39B protein levels (SeqId = 9742-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDX39B protein levels (SeqId = 9742-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Spliceosome RNA helicase DDX39B	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.41	0.096	0.000016	None	Gadd-DA_ddx39b_protein_levels__seqid___9742-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS4X protein levels (SeqId = 9758-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS4X protein levels (SeqId = 9758-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 40S ribosomal protein S4, X isoform	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.41	0.096	0.000016	None	Gadd-DA_rps4x_protein_levels__seqid___9758-17__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17111521	chr5:10309042	5	10309042	CMBL	South shore	0.0363159	0.0084282	0.00001651745	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.035541	0.00825136	0.00001663377	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	-0.035433	0.00825139	0.00001764629	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17111521	chr5:10309042	5	10309042	CMBL	South shore	0.0353992	0.0082514	0.00001797489	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0384213	0.00896785	0.00001844506	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00123333	chr5:10291242	5	10291242	CMBL	Open sea	0.0353082	0.00825142	0.00001888868	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CUL3 protein levels (SeqId = 10045-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CUL3 protein levels (SeqId = 10045-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cullin-3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.41	0.096	0.000019	None	Gadd-DA_cul3_protein_levels__seqid___10045-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	WNK3 protein levels (SeqId = 5493-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WNK3 protein levels (SeqId = 5493-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase WNK3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.41	0.095	0.000019	None	Gadd-DA_wnk3_protein_levels__seqid___5493-17__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17326974	chr5:10290391	5	10290391	CMBL	Open sea	0.0352928	0.00825143	0.00001904799	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Sammallahti S	PACE	None	None	Maternal anxiety during pregnancy	EFO_0005230, EFO_0002950	Meta-analysis using EPIC-only sites	None	DNA methylation	Maternal anxiety during pregnancy	Sex, Cell composition (reference based), Batch effects, Ancestry (other), Socio-economic position, maternal age	Beta Values	None	Illumina MethylationEPIC	Cord blood	Only EPIC-specific sites (which are available on the Illumina EPIC, but not the Illumina 450k array) were included in this meta-analysis	1221	4	Infants	Both	European, African, Admixed	cg22566694	chr5:10309123	5	10309123	CMBL	South shore	None	None	0.0000195	None	Sammallahti-S_maternal_anxiety_during_pregnancy_meta-analysis_using_epic-only_sites
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	0.0395254	0.00925493	0.00001960573	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.0352226	0.00825145	0.00001978849	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	-0.0352127	0.00825145	0.00001989551	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PSIP1 protein levels (SeqId = 17176-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSIP1 protein levels (SeqId = 17176-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PC4 and SFRS1-interacting protein	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.41	0.096	0.00002	None	Gadd-DA_psip1_protein_levels__seqid___17176-13__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	-0.0351719	0.00825146	0.00002034102	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13323825	chr5:10307831	5	10307831	CMBL	Island	0.0351703	0.00825146	0.00002035906	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMD4 protein levels (SeqId = 13568-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMD4 protein levels (SeqId = 13568-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 26S proteasome non-ATPase regulatory subunit 4	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.41	0.096	0.000021	None	Gadd-DA_psmd4_protein_levels__seqid___13568-30__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.0350689	0.00825149	0.00002150898	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0374339	0.00883297	0.00002269307	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0378845	0.0089403	0.00002274096	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	TRIM3 protein levels (SeqId = 12573-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TRIM3 protein levels (SeqId = 12573-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tripartite motif-containing protein 3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.397	0.094	0.000024	None	Gadd-DA_trim3_protein_levels__seqid___12573-80__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.0348501	0.00825156	0.00002420279	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16724323	chr5:10291965	5	10291965	CMBL	Open sea	0.034828	0.00825156	0.00002449283	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GDF9 protein levels (SeqId = 3067-67)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GDF9 protein levels (SeqId = 3067-67)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Growth/differentiation factor 9	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.096	0.000026	None	Gadd-DA_gdf9_protein_levels__seqid___3067-67__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TCEA1 protein levels (SeqId = 18204-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TCEA1 protein levels (SeqId = 18204-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription elongation factor A protein 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.095	0.000026	None	Gadd-DA_tcea1_protein_levels__seqid___18204-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHMT1 protein levels (SeqId = 12334-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHMT1 protein levels (SeqId = 12334-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine hydroxymethyltransferase, cytosolic	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.095	0.000026	None	Gadd-DA_shmt1_protein_levels__seqid___12334-25__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0347146	0.00825159	0.00002603063	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SRGN protein levels (SeqId = 19251-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SRGN protein levels (SeqId = 19251-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serglycin	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.094	0.000027	None	Gadd-DA_srgn_protein_levels__seqid___19251-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACBD6 protein levels (SeqId = 19341-36)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACBD6 protein levels (SeqId = 19341-36)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-CoA-binding domain-containing protein 6	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.096	0.000027	None	Gadd-DA_acbd6_protein_levels__seqid___19341-36__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PNPLA2 protein levels (SeqId = 9802-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PNPLA2 protein levels (SeqId = 9802-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Patatin-like phospholipase domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.401	0.096	0.000028	None	Gadd-DA_pnpla2_protein_levels__seqid___9802-27__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	0.0345497	0.00825164	0.00002843066	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	-0.0344855	0.00825166	0.00002942047	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	-0.0344746	0.00825166	0.00002959247	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMG3 protein levels (SeqId = 12729-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMG3 protein levels (SeqId = 12729-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteasome assembly chaperone 3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.095	0.00003	None	Gadd-DA_psmg3_protein_levels__seqid___12729-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IDE protein levels (SeqId = 3197-70)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IDE protein levels (SeqId = 3197-70)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Insulin-degrading enzyme	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.096	0.00003	None	Gadd-DA_ide_protein_levels__seqid___3197-70__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.147323	0.0353463	0.00003087749	None	39706196_Hannah-M.-Smith_bmi_discovery
Carmona JJ	Normative Aging Study	30343628	2018-10-21	Lung function decline	EFO_0004312, EFO_0003892	Discovery. FVC. Lung function decline in this paper is defined as a decrease in FVC between visits.	Table S1	Lung function decline	DNA methylation	Season, follow up time, batch effects, weight, weight squared, log(height), age, vitamin C intake, years of education, taking corticosteroids or beta-2-adrenergic agonists or AHFS or LAMA, smoking	L	Beta Values	Illumina HumanMethylation450	Whole blood	None	633	1	Adults	Males	European	cg05593349	chr5:10307744	5	10307744	CMBL	Island	0.462	0.111	0.000032	None	30343628_Carmona-JJ_lung_function_decline_discovery__fvc__lung_function_decline_in_this_paper_is_defined_as_a_decrease_in_fvc_between_visits_
Gadd DA	Generation Scotland	35945220	31/07/2022	HIPK3 protein levels (SeqId = 19329-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HIPK3 protein levels (SeqId = 19329-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Homeodomain-interacting protein kinase 3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.096	0.000032	None	Gadd-DA_hipk3_protein_levels__seqid___19329-31__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0343048	0.00825171	0.00003238608	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	0.0367324	0.00884798	0.00003321727	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	DECR2 protein levels (SeqId = 18343-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DECR2 protein levels (SeqId = 18343-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxisomal 2,4-dienoyl-CoA reductase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.095	0.000034	None	Gadd-DA_decr2_protein_levels__seqid___18343-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	POLI protein levels (SeqId = 13536-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	POLI protein levels (SeqId = 13536-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA polymerase iota	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.095	0.000034	None	Gadd-DA_poli_protein_levels__seqid___13536-56__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	0.0342078	0.00825174	0.00003409353	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.0342055	0.00825174	0.00003413609	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	HGD protein levels (SeqId = 9832-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HGD protein levels (SeqId = 9832-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Homogentisate 1,2-dioxygenase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.4	0.096	0.000035	None	Gadd-DA_hgd_protein_levels__seqid___9832-33__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0372836	0.00901633	0.00003567558	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.14923	0.0360974	0.00003580582	None	39706196_Hannah-M.-Smith_bmi_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	MYO6 protein levels (SeqId = 9894-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYO6 protein levels (SeqId = 9894-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Unconventional myosin-VI	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.095	0.000036	None	Gadd-DA_myo6_protein_levels__seqid___9894-13__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	0.0340245	0.00825179	0.00003755629	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	0.00064	None	0.000038	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	AP4M1 protein levels (SeqId = 10076-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AP4M1 protein levels (SeqId = 10076-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AP-4 complex subunit mu-1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.095	0.000039	None	Gadd-DA_ap4m1_protein_levels__seqid___10076-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LTB4R protein levels (SeqId = 13477-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LTB4R protein levels (SeqId = 13477-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leukotriene B4 receptor 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.095	0.000039	None	Gadd-DA_ltb4r_protein_levels__seqid___13477-65__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TARBP2 protein levels (SeqId = 12781-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TARBP2 protein levels (SeqId = 12781-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RISC-loading complex subunit TARBP2	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.095	0.000039	None	Gadd-DA_tarbp2_protein_levels__seqid___12781-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	-0.0338747	0.00825183	0.00004063129	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PMVK protein levels (SeqId = 12450-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PMVK protein levels (SeqId = 12450-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphomevalonate kinase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.393	0.096	0.000041	None	Gadd-DA_pmvk_protein_levels__seqid___12450-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ASF1A protein levels (SeqId = 18172-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASF1A protein levels (SeqId = 18172-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histone chaperone ASF1A	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000041	None	Gadd-DA_asf1a_protein_levels__seqid___18172-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	USP15 protein levels (SeqId = 19161-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	USP15 protein levels (SeqId = 19161-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin carboxyl-terminal hydrolase 15	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.095	0.000043	None	Gadd-DA_usp15_protein_levels__seqid___19161-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LDLRAD4 protein levels (SeqId = 9004-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LDLRAD4 protein levels (SeqId = 9004-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Low-density lipoprotein receptor class A domain-containing protein 4	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000043	None	Gadd-DA_ldlrad4_protein_levels__seqid___9004-24__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18328428	chr5:10291212	5	10291212	CMBL	Open sea	0.0029	None	0.000044	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	RAD1 protein levels (SeqId = 12670-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAD1 protein levels (SeqId = 12670-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cell cycle checkpoint protein RAD1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000044	None	Gadd-DA_rad1_protein_levels__seqid___12670-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRLR protein levels (SeqId = 5114-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRLR protein levels (SeqId = 5114-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prolactin receptor	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000044	None	Gadd-DA_prlr_protein_levels__seqid___5114-65__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0366074	0.00897956	0.00004591018	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS3 protein levels (SeqId = 5026-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS3 protein levels (SeqId = 5026-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 40S ribosomal protein S3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000046	None	Gadd-DA_rps3_protein_levels__seqid___5026-66__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.0336217	0.0082519	0.00004637201	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2E1 protein levels (SeqId = 14326-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2E1 protein levels (SeqId = 14326-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 E1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000047	None	Gadd-DA_ube2e1_protein_levels__seqid___14326-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DBI protein levels (SeqId = 16919-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DBI protein levels (SeqId = 16919-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-CoA-binding protein	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000047	None	Gadd-DA_dbi_protein_levels__seqid___16919-1__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26878318	chr5:10308785	5	10308785	CMBL	South shore	-0.00059	0.00015	0.000048	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	SHC1 protein levels (SeqId = 5272-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHC1 protein levels (SeqId = 5272-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SHC-transforming protein 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.095	0.000048	None	Gadd-DA_shc1_protein_levels__seqid___5272-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	S100A4 protein levels (SeqId = 14116-129)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	S100A4 protein levels (SeqId = 14116-129)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein S100-A4	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000048	None	Gadd-DA_s100a4_protein_levels__seqid___14116-129__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP3CA protein levels (SeqId = 4903-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP3CA protein levels (SeqId = 4903-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcineurin subunit B type 1|Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.095	0.000048	None	Gadd-DA_ppp3ca_protein_levels__seqid___4903-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3GLB2 protein levels (SeqId = 18222-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3GLB2 protein levels (SeqId = 18222-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endophilin-B2	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000049	None	Gadd-DA_sh3glb2_protein_levels__seqid___18222-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VAV1 protein levels (SeqId = 5275-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VAV1 protein levels (SeqId = 5275-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proto-oncogene vav	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.095	0.000049	None	Gadd-DA_vav1_protein_levels__seqid___5275-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	-0.0334417	0.00825195	0.00005091582	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Kazmi N	PACE	31230546	2019-06-24	Preeclampsia	EFO_0000668	Meta analysis unadjusted model	Table S5	DNA methylation	Preeclampsia	Cell composition (reference based), batch effects, age, smoking, parity, diabetes, body mass index, sex	Beta Values	None	Illumina HumanMethylation450	Cord blood	None	3460	6	Infants	Both	Unclear	cg00123333	chr5:10291242	5	10291242	CMBL	Open sea	-0.0057	0.0014	0.000053	None	31230546_Kazmi-N_preeclampsia_meta_analysis_unadjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPOLG protein levels (SeqId = 8343-224)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPOLG protein levels (SeqId = 8343-224)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Poly(A) polymerase gamma	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000053	None	Gadd-DA_papolg_protein_levels__seqid___8343-224__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0361727	0.00895302	0.00005366066	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMA6 protein levels (SeqId = 3860-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMA6 protein levels (SeqId = 3860-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteasome subunit alpha type-6	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000054	None	Gadd-DA_psma6_protein_levels__seqid___3860-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	-0.0332984	0.00825199	0.00005483419	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	EHBP1 protein levels (SeqId = 12813-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EHBP1 protein levels (SeqId = 12813-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: EH domain-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000055	None	Gadd-DA_ehbp1_protein_levels__seqid___12813-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TESC protein levels (SeqId = 12831-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TESC protein levels (SeqId = 12831-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcineurin B homologous protein 3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000055	None	Gadd-DA_tesc_protein_levels__seqid___12831-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SEZ6L2 protein levels (SeqId = 3867-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SEZ6L2 protein levels (SeqId = 3867-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Seizure 6-like protein 2	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000055	None	Gadd-DA_sez6l2_protein_levels__seqid___3867-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ING1 protein levels (SeqId = 3888-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ING1 protein levels (SeqId = 3888-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inhibitor of growth protein 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000056	None	Gadd-DA_ing1_protein_levels__seqid___3888-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CARHSP1 protein levels (SeqId = 12808-103)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CARHSP1 protein levels (SeqId = 12808-103)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium-regulated heat-stable protein 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000056	None	Gadd-DA_carhsp1_protein_levels__seqid___12808-103__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSH1 protein levels (SeqId = 13103-125)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSH1 protein levels (SeqId = 13103-125)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chorionic somatomammotropin hormone 2|Chorionic somatomammotropin hormone 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000057	None	Gadd-DA_csh1_protein_levels__seqid___13103-125__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK9 protein levels (SeqId = 15604-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK9 protein levels (SeqId = 15604-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 9	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000058	None	Gadd-DA_mapk9_protein_levels__seqid___15604-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADH5 protein levels (SeqId = 11369-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADH5 protein levels (SeqId = 11369-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alcohol dehydrogenase class-3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.39	0.096	0.000058	None	Gadd-DA_adh5_protein_levels__seqid___11369-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHC1 protein levels (SeqId = 16043-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHC1 protein levels (SeqId = 16043-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SHC-transforming protein 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000059	None	Gadd-DA_shc1_protein_levels__seqid___16043-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DTD2 protein levels (SeqId = 18280-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DTD2 protein levels (SeqId = 18280-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: D-aminoacyl-tRNA deacylase 2	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000059	None	Gadd-DA_dtd2_protein_levels__seqid___18280-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	-0.0330916	0.00825205	0.00006099252	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TRDMT1 protein levels (SeqId = 12635-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TRDMT1 protein levels (SeqId = 12635-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: tRNA (cytosine(38)-C(5))-methyltransferase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000061	None	Gadd-DA_trdmt1_protein_levels__seqid___12635-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CAPNS1 protein levels (SeqId = 18299-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAPNS1 protein levels (SeqId = 18299-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calpain small subunit 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000061	None	Gadd-DA_capns1_protein_levels__seqid___18299-13__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	-0.0330866	0.00825205	0.00006114723	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.0370704	0.00924827	0.00006144547	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0330706	0.00825206	0.00006165404	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17111521	chr5:10309042	5	10309042	CMBL	South shore	0.0336826	0.00840727	0.00006196495	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	DLG4 protein levels (SeqId = 8070-88)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DLG4 protein levels (SeqId = 8070-88)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Disks large homolog 4	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000062	None	Gadd-DA_dlg4_protein_levels__seqid___8070-88__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	0.0368386	0.00920197	0.00006276347	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	NAP1L1 protein levels (SeqId = 13636-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAP1L1 protein levels (SeqId = 13636-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nucleosome assembly protein 1-like 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000063	None	Gadd-DA_nap1l1_protein_levels__seqid___13636-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HGS protein levels (SeqId = 13644-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HGS protein levels (SeqId = 13644-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatocyte growth factor-regulated tyrosine kinase substrate	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000064	None	Gadd-DA_hgs_protein_levels__seqid___13644-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RRBP1 protein levels (SeqId = 9913-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RRBP1 protein levels (SeqId = 9913-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribosome-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000065	None	Gadd-DA_rrbp1_protein_levels__seqid___9913-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ASH2L protein levels (SeqId = 12832-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASH2L protein levels (SeqId = 12832-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Set1/Ash2 histone methyltransferase complex subunit ASH2	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000065	None	Gadd-DA_ash2l_protein_levels__seqid___12832-10__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17111521	chr5:10309042	5	10309042	CMBL	South shore	0.0335825	0.00841163	0.00006572818	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	TDP1 protein levels (SeqId = 10073-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TDP1 protein levels (SeqId = 10073-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosyl-DNA phosphodiesterase 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000066	None	Gadd-DA_tdp1_protein_levels__seqid___10073-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PGK1 protein levels (SeqId = 5020-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGK1 protein levels (SeqId = 5020-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphoglycerate kinase 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000066	None	Gadd-DA_pgk1_protein_levels__seqid___5020-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BLMH protein levels (SeqId = 14250-115)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BLMH protein levels (SeqId = 14250-115)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bleomycin hydrolase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000067	None	Gadd-DA_blmh_protein_levels__seqid___14250-115__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	0.0328965	0.0082521	0.00006739679	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	-0.0328877	0.00825211	0.00006770105	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	RPIA protein levels (SeqId = 12333-87)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPIA protein levels (SeqId = 12333-87)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribose-5-phosphate isomerase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000068	None	Gadd-DA_rpia_protein_levels__seqid___12333-87__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SGK3 protein levels (SeqId = 10042-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SGK3 protein levels (SeqId = 10042-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase Sgk3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.382	0.096	0.000068	None	Gadd-DA_sgk3_protein_levels__seqid___10042-8__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	0.0328691	0.00825211	0.00006834572	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17467873	chr5:10307544	5	10307544	CMBL	Island	0.0328581	0.00825211	0.00006873223	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	WWP1 protein levels (SeqId = 11307-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WWP1 protein levels (SeqId = 11307-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NEDD4-like E3 ubiquitin-protein ligase WWP1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.00007	None	Gadd-DA_wwp1_protein_levels__seqid___11307-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF16 protein levels (SeqId = 4393-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF16 protein levels (SeqId = 4393-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 16	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.00007	None	Gadd-DA_fgf16_protein_levels__seqid___4393-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBL4A protein levels (SeqId = 11490-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBL4A protein levels (SeqId = 11490-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-like protein 4A	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000071	None	Gadd-DA_ubl4a_protein_levels__seqid___11490-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GDF5 protein levels (SeqId = 2752-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GDF5 protein levels (SeqId = 2752-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Growth/differentiation factor 5	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000072	None	Gadd-DA_gdf5_protein_levels__seqid___2752-62__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IFNL1 protein levels (SeqId = 4396-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFNL1 protein levels (SeqId = 4396-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon lambda-1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000072	None	Gadd-DA_ifnl1_protein_levels__seqid___4396-54__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMPO protein levels (SeqId = 8265-225)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMPO protein levels (SeqId = 8265-225)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lamina-associated polypeptide 2, isoforms beta/gamma	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000072	None	Gadd-DA_tmpo_protein_levels__seqid___8265-225__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2I protein levels (SeqId = 2877-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2I protein levels (SeqId = 2877-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SUMO-conjugating enzyme UBC9	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000072	None	Gadd-DA_ube2i_protein_levels__seqid___2877-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2L3 protein levels (SeqId = 3874-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2L3 protein levels (SeqId = 3874-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 L3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000073	None	Gadd-DA_ube2l3_protein_levels__seqid___3874-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKAA2 protein levels (SeqId = 5245-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKAA2 protein levels (SeqId = 5245-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 5'-AMP-activated protein kinase subunit beta-2|5'-AMP-activated protein kinase catalytic subunit alpha-2|5'-AMP-activated protein kinase subunit gamma-1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000073	None	Gadd-DA_prkaa2_protein_levels__seqid___5245-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MTHFS protein levels (SeqId = 14107-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MTHFS protein levels (SeqId = 14107-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 5-formyltetrahydrofolate cyclo-ligase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000073	None	Gadd-DA_mthfs_protein_levels__seqid___14107-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	0.032716	0.00825215	0.00007388682	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPF protein levels (SeqId = 9764-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPF protein levels (SeqId = 9764-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein F	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000074	None	Gadd-DA_hnrnpf_protein_levels__seqid___9764-79__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04430	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04430	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	-0.0326923	0.00825216	0.00007478111	P04430	41361833_Josephine_Robertson_P04430_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TLN2 protein levels (SeqId = 14082-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TLN2 protein levels (SeqId = 14082-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Talin-2	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000075	None	Gadd-DA_tln2_protein_levels__seqid___14082-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RQCD1 protein levels (SeqId = 8975-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RQCD1 protein levels (SeqId = 8975-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: CCR4-NOT transcription complex subunit 9	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000075	None	Gadd-DA_rqcd1_protein_levels__seqid___8975-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CROT protein levels (SeqId = 13929-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CROT protein levels (SeqId = 13929-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxisomal carnitine O-octanoyltransferase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.094	0.000075	None	Gadd-DA_crot_protein_levels__seqid___13929-27__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08390666	chr5:10304106	5	10304106	CMBL	North shelf	-0.0326673	0.00825216	0.00007573471	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJA4 protein levels (SeqId = 9744-139)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJA4 protein levels (SeqId = 9744-139)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily A member 4	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000077	None	Gadd-DA_dnaja4_protein_levels__seqid___9744-139__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	0.0326259	0.00825218	0.00007734207	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TMEM38B protein levels (SeqId = 9509-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMEM38B protein levels (SeqId = 9509-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Trimeric intracellular cation channel type B	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.094	0.000078	None	Gadd-DA_tmem38b_protein_levels__seqid___9509-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACOT8 protein levels (SeqId = 17400-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACOT8 protein levels (SeqId = 17400-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-coenzyme A thioesterase 8	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.378	0.096	0.000078	None	Gadd-DA_acot8_protein_levels__seqid___17400-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MLEC protein levels (SeqId = 6285-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MLEC protein levels (SeqId = 6285-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Malectin	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000078	None	Gadd-DA_mlec_protein_levels__seqid___6285-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CASC4 protein levels (SeqId = 8838-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASC4 protein levels (SeqId = 8838-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein CASC4	774	1	Adults (18-65 years)	Both	European	cg22566694	chr5:10309123	5	10309123	CMBL	South shore	-0.69	0.17	0.000079	None	Gadd-DA_casc4_protein_levels__seqid___8838-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS6KB1 protein levels (SeqId = 15608-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS6KB1 protein levels (SeqId = 15608-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribosomal protein S6 kinase beta-1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000079	None	Gadd-DA_rps6kb1_protein_levels__seqid___15608-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAN protein levels (SeqId = 4282-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAN protein levels (SeqId = 4282-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GTP-binding nuclear protein Ran	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000079	None	Gadd-DA_ran_protein_levels__seqid___4282-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	-0.0325326	0.0082522	0.00008108067	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS19 protein levels (SeqId = 19166-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS19 protein levels (SeqId = 19166-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 40S ribosomal protein S19	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000082	None	Gadd-DA_rps19_protein_levels__seqid___19166-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAF1 protein levels (SeqId = 10001-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAF1 protein levels (SeqId = 10001-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RAF proto-oncogene serine/threonine-protein kinase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.095	0.000082	None	Gadd-DA_raf1_protein_levels__seqid___10001-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	0.032489	0.00825221	0.0000828845	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PABPN1 protein levels (SeqId = 8921-139)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PABPN1 protein levels (SeqId = 8921-139)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Polyadenylate-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.095	0.000083	None	Gadd-DA_pabpn1_protein_levels__seqid___8921-139__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03519739	chr5:10293513	5	10293513	CMBL	Open sea	0.0324576	0.00825222	0.00008420977	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	-0.0324417	0.00825223	0.00008488762	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TMOD3 protein levels (SeqId = 12861-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMOD3 protein levels (SeqId = 12861-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tropomodulin-3	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.095	0.000085	None	Gadd-DA_tmod3_protein_levels__seqid___12861-13__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	-0.0324056	0.00825224	0.0000864453	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	YBX2 protein levels (SeqId = 6372-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YBX2 protein levels (SeqId = 6372-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Y-box-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000087	None	Gadd-DA_ybx2_protein_levels__seqid___6372-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPD protein levels (SeqId = 18348-89)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPD protein levels (SeqId = 18348-89)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein D0	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000088	None	Gadd-DA_hnrnpd_protein_levels__seqid___18348-89__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RRM2B protein levels (SeqId = 8925-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RRM2B protein levels (SeqId = 8925-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribonucleoside-diphosphate reductase subunit M2 B	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000088	None	Gadd-DA_rrm2b_protein_levels__seqid___8925-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AGAP2 protein levels (SeqId = 14291-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AGAP2 protein levels (SeqId = 14291-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.38	0.096	0.000088	None	Gadd-DA_agap2_protein_levels__seqid___14291-53__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	0.0323296	0.00825226	0.00008981328	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02299602	chr5:10293612	5	10293612	CMBL	Open sea	-0.0362311	0.00925087	0.0000902494	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10178203	chr5:10308250	5	10308250	CMBL	South shore	-0.0322994	0.00825226	0.00009118585	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	BPNT1 protein levels (SeqId = 17814-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BPNT1 protein levels (SeqId = 17814-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 3'(2'),5'-bisphosphate nucleotidase 1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.096	0.000092	None	Gadd-DA_bpnt1_protein_levels__seqid___17814-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TREML2 protein levels (SeqId = 5736-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TREML2 protein levels (SeqId = 5736-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Trem-like transcript 2 protein	774	1	Adults (18-65 years)	Both	European	cg25043403	chr5:10305291	5	10305291	CMBL	North shelf	0.72	0.184	0.000092	None	Gadd-DA_treml2_protein_levels__seqid___5736-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11591758	chr5:10279005	5	10279005	CMBL	Open sea	0.0322603	0.00825227	0.00009299394	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PBRM1 protein levels (SeqId = 12518-289)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PBRM1 protein levels (SeqId = 12518-289)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein polybromo-1	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.096	0.000094	None	Gadd-DA_pbrm1_protein_levels__seqid___12518-289__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16459171	chr5:10295079	5	10295079	CMBL	Open sea	-0.0348749	0.00893203	0.00009485118	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	NAGK protein levels (SeqId = 3894-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAGK protein levels (SeqId = 3894-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-acetyl-D-glucosamine kinase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.096	0.000096	None	Gadd-DA_nagk_protein_levels__seqid___3894-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APLN protein levels (SeqId = 6622-90)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APLN protein levels (SeqId = 6622-90)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Apelin	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.096	0.000096	None	Gadd-DA_apln_protein_levels__seqid___6622-90__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COMMD7 protein levels (SeqId = 2823-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COMMD7 protein levels (SeqId = 2823-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: COMM domain-containing protein 7	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.096	0.000096	None	Gadd-DA_commd7_protein_levels__seqid___2823-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16575104	chr5:10308246	5	10308246	CMBL	South shore	-0.0321887	0.00825229	0.00009639196	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	HDGF protein levels (SeqId = 16758-96)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDGF protein levels (SeqId = 16758-96)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatoma-derived growth factor	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.096	0.000098	None	Gadd-DA_hdgf_protein_levels__seqid___16758-96__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DLX4 protein levels (SeqId = 11910-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DLX4 protein levels (SeqId = 11910-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Homeobox protein DLX-4	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.095	0.000098	None	Gadd-DA_dlx4_protein_levels__seqid___11910-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GALNT13 protein levels (SeqId = 10908-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GALNT13 protein levels (SeqId = 10908-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Polypeptide N-acetylgalactosaminyltransferase 13	774	1	Adults (18-65 years)	Both	European	cg23284609	chr5:10306947	5	10306947	CMBL	North shore	0.92	0.236	0.000099	None	Gadd-DA_galnt13_protein_levels__seqid___10908-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HMHA1 protein levels (SeqId = 13544-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HMHA1 protein levels (SeqId = 13544-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 45	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.096	0.000099	None	Gadd-DA_hmha1_protein_levels__seqid___13544-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NANP protein levels (SeqId = 16863-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NANP protein levels (SeqId = 16863-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-acylneuraminate-9-phosphatase	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.096	0.000099	None	Gadd-DA_nanp_protein_levels__seqid___16863-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TGFB1 protein levels (SeqId = 2333-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TGFB1 protein levels (SeqId = 2333-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transforming growth factor beta-1 proprotein	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.095	0.000099	None	Gadd-DA_tgfb1_protein_levels__seqid___2333-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDKN2D protein levels (SeqId = 12376-85)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDKN2D protein levels (SeqId = 12376-85)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cyclin-dependent kinase 4 inhibitor D	774	1	Adults (18-65 years)	Both	European	cg19804008	chr5:10293133	5	10293133	CMBL	Open sea	0.37	0.096	0.000099	None	Gadd-DA_cdkn2d_protein_levels__seqid___12376-85__somascan_protein_measurement