author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Sayols-Baixeras S	-	28173150	2016-09-15	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication	Table S1	Serum triglycerides	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	Triglycerides levels were log-transformed	3187	2	65.7	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.055	0.004	0	-	28173150_serum_triglycerides_discovery_and_replication
Sayols-Baixeras S	-	28173150	2016-09-15	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for surrogate variables	Table S1	Serum triglycerides	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	Triglycerides levels were log-transformed	3187	2	65.7	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.075	0.005	0	-	28173150_serum_triglycerides_discovery_and_replication_adjusted_for_surrogate_variables
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02617757	chr11:68609597	11	68609597	CPT1A	North shore	-0.000075	0.0000074	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03475843	chr11:68529097	11	68529097	CPT1A	Open sea	-0.0021	0.00019	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03855388	chr11:68580018	11	68580018	CPT1A	Open sea	-0.00041	0.000037	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05362892	chr11:68583422	11	68583422	CPT1A	Open sea	-0.0011	0.00013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07669138	chr11:68583531	11	68583531	CPT1A	Open sea	-0.0028	0.00026	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08723623	chr11:68541465	11	68541465	CPT1A	Open sea	-0.00094	0.0001	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.00077	0.000092	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09806934	chr11:68608813	11	68608813	CPT1A	Island	0.00047	0.00005	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09972762	chr11:68553421	11	68553421	CPT1A	South shelf	-0.0012	0.000092	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10703936	chr11:68549447	11	68549447	CPT1A	North shore	-0.0056	0.00026	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12598007	chr11:68607069	11	68607069	CPT1A	Island	0.00061	0.00006	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12691334	chr11:68610186	11	68610186	CPT1A	North shore	-0.025	0.0023	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14247222	chr11:68549334	11	68549334	CPT1A	North shore	-0.0012	0.000097	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18262591	chr11:68579970	11	68579970	CPT1A	Open sea	-0.00085	0.000085	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19417588	chr11:68529067	11	68529067	CPT1A	Open sea	-0.0028	0.00021	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21868480	chr11:68547532	11	68547532	CPT1A	North shelf	-0.0018	0.00016	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.003	0.00018	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.01	0.0012	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23404110	chr11:68609590	11	68609590	CPT1A	North shore	-0.000083	0.0000073	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23406642	chr11:68549255	11	68549255	CPT1A	North shore	-0.0033	0.00021	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0016	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.872949	0.029524	1.78362e-187	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.839935	0.0297801	3.795307e-171	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg06042565	chr11:68564477	11	68564477	CPT1A	Open sea	0.44946	0.00556	9.9e-151	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.719402	0.0277898	5.290316e-145	None	39706196_Hannah-M.-Smith_bmi_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15616358	chr11:68610296	11	68610296	CPT1A	North shore	-0.4186	0.00565	1.1e-143	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.698554	0.0278866	4.6247799999999995e-136	None	39706196_Hannah-M.-Smith_body_fat_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26906629	chr11:68564367	11	68564367	CPT1A	Open sea	0.32608	0.00561	2.8000000000000004e-124	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18445292	chr11:68610381	11	68610381	CPT1A	North shore	-0.33691	0.00598	9e-122	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.661794	0.0287651	2.147402e-115	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.34435	0.00699	2.7000000000000003e-111	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.674508	0.0299103	5.228487e-111	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.648046	0.0289752	3.019161e-109	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.28419	0.00594	5e-109	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12691334	chr11:68610186	11	68610186	CPT1A	North shore	-0.23071	0.00484	9e-109	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13786863	chr11:68610743	11	68610743	CPT1A	North shore	-0.29896	0.00647	2.6e-106	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.562381	0.0259542	9.529372e-103	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20285002	chr11:68583898	11	68583898	CPT1A	Open sea	0.12035	0.00294	5.1e-97	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20629021	chr11:68580041	11	68580041	CPT1A	Open sea	0.26089	0.00645	3.3e-96	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.537564	0.0261573	9.633881e-93	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.167348	0.00814014	1.301456e-92	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.166012	0.008142	3.7794499999999997e-91	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19596755	chr11:68609747	11	68609747	CPT1A	North shore	-0.12985	0.00344	5e-91	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15211864	chr11:68531232	11	68531232	CPT1A	Open sea	0.10606	0.00281	5.8e-91	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.165651	0.00828292	8.276476e-88	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.557257	0.027982	2.874157e-87	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04732324	chr11:68564292	11	68564292	CPT1A	Open sea	0.08196	0.0023	6e-87	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.162028	0.00814747	7.341022e-87	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.160427	0.00814963	3.6202109999999995e-85	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.55547	0.0289784	4.713739000000001e-81	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg03855388	chr11:68580018	11	68580018	CPT1A	Open sea	0.19437	0.00604	1.8e-79	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24366211	chr11:68610706	11	68610706	CPT1A	North shore	-0.16918	0.00546	7e-77	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.151861	0.00828115	2.773307e-74	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18262591	chr11:68579970	11	68579970	CPT1A	Open sea	0.001	None	3.8e-73	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.18287	0.00627	1.3e-72	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.46998	0.0261354	1.201953e-71	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.143145	0.00817154	5.185076e-68	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.14189	0.00523	7.899999999999999e-68	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.450101	0.0258632	2.920668e-67	None	39706196_Hannah-M.-Smith_body_fat_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.442882	0.0258103	1.870598e-65	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.138969	0.00817646	3.60225e-64	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.138065	0.0081775	2.3581139999999998e-63	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.136494	0.0081793	5.99586e-62	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.136485	0.00830819	4.163023e-60	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4261	5	65	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0098643	0.0006066	1.8700000000000001e-59	-	28213390_serum_triglycerides_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.131713	0.00818464	8.96727e-58	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19964581	chr11:68540558	11	68540558	CPT1A	Open sea	0.00076	None	9.200000000000001e-58	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Sayols-Baixeras S	-	28173150	2016-09-15	Serum triglycerides	EFO_0004530, CHEBI_17855	Replication adjusted for surrogate variables	Table S1	Serum triglycerides	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	Triglycerides levels were log-transformed	2542	1	66.3	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.08	0.005	4.2e-56	-	28173150_serum_triglycerides_replication_adjusted_for_surrogate_variables
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.459653	0.0293744	7.796318000000001e-55	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.1265	0.00819024	2.139009e-53	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.376905	0.0246722	2.409419e-52	None	39706196_Hannah-M.-Smith_body_fat_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	0.13991	0.00673	4.2e-51	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.37097	0.0246203	5.568824e-51	None	39706196_Hannah-M.-Smith_bmi_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.384438	0.025844	9.678541e-50	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	6.799999999999999e-49	-	28002404_body_mass_index_discovery_and_replication
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05710301	chr11:68540704	11	68540704	CPT1A	Open sea	0.05273	0.00266	1.7e-48	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.119845	0.00819706	4.527624e-48	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-	-	5.1299999999999994e-48	-	23526956_clear_cell_renal_carcinoma
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.399642	0.0274162	7.332934e-48	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.06406	0.00328	1.6e-47	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	3.44e-47	-	25935004_body_mass_index_metaanalysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.118662	0.00819824	3.732216e-47	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.13162	0.00909869	4.207767e-47	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg25890640	chr11:68610632	11	68610632	CPT1A	North shore	-0.06005	0.00313	1.1e-46	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.119333	0.00833825	3.795788e-46	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.13098	0.00916288	4.820725e-46	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.001	None	6e-46	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Sayols-Baixeras S	-	28173150	2016-09-15	Serum triglycerides	EFO_0004530, CHEBI_17855	Replication	Table S1	Serum triglycerides	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	Triglycerides levels were log-transformed	2542	1	66.3	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.063	0.004	1e-44	-	28173150_serum_triglycerides_replication
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.412968	0.0295344	3.366027e-44	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.158341	0.0113323	4.404917e-44	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_4
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-7.9	0.565	4.8e-44	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.112995	0.00820369	6.7869870000000004e-43	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.125574	0.00914642	1.24313e-42	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4261	5	65	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0086	6e-04	2.4199999999999998e-42	-	28213390_serum_triglycerides_discovery_and_replication_adjusted_for_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.112142	0.00820449	2.8454689999999998e-42	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.335647	0.0246302	4.534896e-42	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20201954	chr11:68609518	11	68609518	CPT1A	North shore	0.01707	0.001	1.1e-40	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.123901	0.00931294	3.740363e-40	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.109134	0.00820726	4.100038e-40	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.123853	0.00933498	6.064659e-40	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.360979	0.0273828	1.6724140000000002e-39	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg01926073	chr11:68565744	11	68565744	CPT1A	Open sea	-2.00219	0.08516	1.87e-39	-	25282492_fetal_vs_adult_liver
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02100918	chr11:68550982	11	68550982	CPT1A	South shore	0.03349	0.002	1.8999999999999998e-39	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	sensitivity	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.393048	0.0301224	9.760323e-39	None	39706196_Hannah-M.-Smith_glucose_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.107055	0.00820912	1.173714e-38	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Waist circumference	EFO_0004342	Meta-analysis model 2	Supplementary table 4	Waist circumference	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	cm	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-3.9	0.3	1.2e-38	None	29099282_Sayols-Baixeras-S_waist_circumference_meta-analysis_model_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	5.77e-38	-	25935004_body_mass_index_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.10627	0.00825674	1.053202e-37	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells, leukocytes and whole blood	-	5474	4	59.1	Both	European,African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	3.5e-37	-	26110892_body_mass_index_metaanalysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.104768	0.00821113	4.359226e-37	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.368189	0.0289673	7.558999e-37	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.103805	0.00817336	9.188539e-37	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.131403	0.0103783	1.503527e-36	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_4
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4261	5	65	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0108047	0.0008573	2.03e-36	-	28213390_serum_triglycerides_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.104553	0.00832237	5.1756919999999997e-36	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.119545	0.00952013	5.573358e-36	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_4
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Waist circumference	EFO_0004342	Meta-analysis model 1	Supplementary table 4	Waist circumference	DNA methylation	Age, sex, smoking, cell composition (reference based)	cm	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-2.5	0.2	7.5e-36	None	29099282_Sayols-Baixeras-S_waist_circumference_meta-analysis_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.102907	0.00821274	7.79427e-36	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.104504	0.00835532	1.034358e-35	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14247222	chr11:68549334	11	68549334	CPT1A	North shore	0.001	None	1.5e-35	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0089987	0.0007236	1.65e-35	-	28213390_serum_triglycerides_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.362476	0.029161	2.538055e-35	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.115033	0.0093479	1.249287e-34	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09972762	chr11:68553421	11	68553421	CPT1A	South shelf	0.00092	None	2.3e-34	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.113198	0.00932124	8.964567e-34	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-40.2	3.1	3.3e-33	-	28002404_body_mass_index_all_ancestry_discovery
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	S-LDL-TG	None	Meta-analysis	Table S2	DNA methylation	S-LDL-TG	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Triglycerides in small LDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-4.1	0.35	4.3e-33	None	33413638_Gomez-Alonso-MDC_s-ldl-tg_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.110003	0.00918681	6.918701e-33	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0979433	0.00821687	1.3203200000000002e-32	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-1.3	0.11	3.1e-32	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.128771	0.0108697	3.136136e-32	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.097284	0.00821741	3.447503e-32	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.097264	0.00821742	3.549202e-32	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18262591	chr11:68579970	11	68579970	CPT1A	Open sea	0.03353	0.00234	3.7e-32	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg15616358	chr11:68610296	11	68610296	CPT1A	North shore	-1.56455	0.0839	3.8200000000000003e-32	-	25282492_fetal_vs_adult_liver
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.068	0.00583	8.999999999999999e-32	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.332661	0.028312	9.216951e-32	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0963371	0.00821817	1.352904e-31	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0976644	0.00834172	1.603044e-31	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0970556	0.00831916	2.598762e-31	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.331474	0.0284401	2.788283e-31	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0958091	0.00821859	2.882518e-31	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0957774	0.00821861	3.016145e-31	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.338417	0.0290708	3.330426e-31	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0956767	0.00821869	3.4820990000000003e-31	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0955353	0.00821881	4.260152000000001e-31	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12031060	chr11:68550320	11	68550320	CPT1A	Island	0.0014	None	4.4999999999999995e-31	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.322506	0.0278913	8.170955e-31	None	39706196_Hannah-M.-Smith_glucose_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0942752	0.0082198	2.534617e-30	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	sensitivity	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.33336	0.0290905	2.690342e-30	None	39706196_Hannah-M.-Smith_glucose_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.105304	0.00918671	2.7342400000000002e-30	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.108995	0.00951123	2.832644e-30	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.106932	0.00939226	6.627731e-30	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.106193	0.00935111	9.204037e-30	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0933411	0.00822052	9.361829e-30	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	2.2e-29	-	28095459_body_mass_index_metaanalysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0923303	0.0082213	3.793325e-29	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4261	5	65	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.01	9e-04	5.48e-29	-	28213390_serum_triglycerides_discovery_and_replication_adjusted_for_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0914373	0.00822198	1.289217e-28	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	0.0273	0.0021	4.1e-28	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0951057	0.0086344	4.182803000000001e-28	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_4
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg23404110	chr11:68609590	11	68609590	CPT1A	North shore	-2.42498	0.15037	7.14e-28	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0897553	0.00822325	1.2505199999999999e-27	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0927844	0.00850893	1.4020250000000001e-27	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.100755	0.0092549	1.699507e-27	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.084266	0.0077415	1.731822e-27	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0890376	0.00822378	3.255258e-27	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-42.08	3.9	3.5e-27	-	28002404_body_mass_index_european_ancestry_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.100086	0.00931235	7.653221e-27	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.12	0.0113	9.9e-27	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Irvin MR	-	24920721	2014-08-12	Triglycerides	EFO_0004530	Discovery	Table 1	DNA methylation	Triglycerides	Age, sex and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	CD4+ T-cells	Triglycerides levels were log-transformed	991	1	49	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.032	0.00299	1.5600000000000002e-26	-	24920721_triglycerides
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Replication	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1955	3	61	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0119788	0.0011262	2.01e-26	-	28213390_serum_triglycerides_replication
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	S-VLDL-TG_pct	None	Meta-analysis	Table S2	DNA methylation	S-VLDL-TG_pct	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	%	Illumina HumanMethylation450	Whole blood	Triglycerides to total lipids ratio in small VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-1.8	0.17	2.1e-26	None	33413638_Gomez-Alonso-MDC_s-vldl-tg_pct_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0889331	0.00836273	2.569193e-26	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for lipid-lowering medication use	Table 3	DNA methylation	Triglycerides	Age, sex, smoking, lipid-lowering medication use, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0142	0.0013	2.6e-26	-	28194238_triglycerides_discovery_and_replication_lipidlowering_medication_use_adjusted
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg26906629	chr11:68564367	11	68564367	CPT1A	Open sea	-	-	2.7300000000000003e-26	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0873645	0.008225	2.938603e-26	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0872743	0.00822507	3.304841e-26	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0872324	0.0082251	3.490053e-26	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication	Table S1	DNA methylation	Triglycerides	Age, sex, smoking, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0139	0.0013	5.07e-26	-	28194238_triglycerides_discovery_and_replication
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0079025	0.00075	5.810000000000001e-26	-	28213390_serum_triglycerides_discovery_adjusted_for_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.114941	0.0109345	9.420460000000001e-26	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.485132	0.046374	1.536789e-25	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00088	None	1.9e-25	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0873471	0.00836733	2.01874e-25	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0857756	0.00822614	2.285e-25	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0978966	0.00939146	2.36346e-25	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_4
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13491471	chr11:68575385	11	68575385	CPT1A	Open sea	0.01688	0.00141	3.4999999999999997e-25	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0853618	0.00822644	3.87429e-25	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.253167	0.0244223	4.159886e-25	None	39706196_Hannah-M.-Smith_glucose_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0850871	0.00822663	5.492818e-25	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27175470	chr11:68575176	11	68575176	CPT1A	Open sea	0.0019	None	7.2e-25	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0847389	0.00822687	8.535971e-25	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0876926	0.00851822	9.03924e-25	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0958326	0.00931273	9.44398e-25	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0846464	0.00822694	9.594391e-25	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.13	0.013	1.0999999999999998e-24	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0928902	0.00904216	1.130506e-24	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	sensitivity	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.269214	0.0262222	1.166202e-24	None	39706196_Hannah-M.-Smith_glucose_sensitivity
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0422	0.00403	1.18e-24	-	28095459_body_mass_index_framingham_heart_study_batch_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.113595	0.0110709	1.2842649999999999e-24	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.101796	0.00995486	1.836739e-24	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0935917	0.00915278	1.841697e-24	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	FHS 1	Table 2	DNA methylation	Body mass index	Age, sex and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	1935	1	65	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.04	0.004	2.4e-24	-	26110892_body_mass_index_fhs_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05710301	chr11:68540704	11	68540704	CPT1A	Open sea	0.0018	None	2.5e-24	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg12691334	chr11:68610186	11	68610186	CPT1A	North shore	-1.25904	0.08884	2.52e-24	-	25282492_fetal_vs_adult_liver
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.260598	0.0256883	4.0582359999999996e-24	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0831266	0.008228	6.422088e-24	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0844875	0.00836655	6.732687e-24	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0896389	0.00890786	9.623101e-24	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0827504	0.00822825	1.0227210000000001e-23	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	S-LDL-TG_pct	None	Meta-analysis	Table S2	DNA methylation	S-LDL-TG_pct	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	%	Illumina HumanMethylation450	Whole blood	Triglycerides to total lipids ratio in small LDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-2.52	0.25	1.1e-23	None	33413638_Gomez-Alonso-MDC_s-ldl-tg_pct_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0931377	0.00928495	1.3266800000000002e-23	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0837603	0.00835107	1.34206e-23	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.251261	0.0251392	1.845148e-23	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.110884	0.0111018	2.0463360000000002e-23	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3379708 (gene symbol: MRPL21)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3379708 (gene symbol: MRPL21)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	None	None	2.4e-23	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3379708__gene_symbol__mrpl21__meta-analysis
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.12	0.0119	2.4e-23	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0820353	0.00822874	2.462553e-23	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Discovery and replication	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	979	1	48.3	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-38.5	3.77	2.69e-23	-	27777315_postprandial_lipemia_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0836405	0.00840914	3.098101e-23	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.254378	0.0256244	3.640365e-23	None	39706196_Hannah-M.-Smith_glucose_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0816092	0.00822903	4.1420290000000005e-23	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0921251	0.00929092	4.210794e-23	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0825975	0.00834379	4.951445e-23	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0906098	0.00918417	6.896511e-23	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.009858	0.0010028	8.329999999999999e-23	-	28213390_serum_triglycerides_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0808774	0.00822952	1.005308e-22	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0805766	0.00822972	1.444132e-22	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for other lipids	Table 3	DNA methylation	Triglycerides	Age, sex, smoking, other lipids, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0161	0.0016	1.5000000000000002e-22	-	28194238_triglycerides_discovery_and_replication_other_lipids_adjusted
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	None	None	2e-22	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.24864	0.0255902	2.91301e-22	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Nones K	-	24500968	2014-05-09	Pancreatic ductal adenocarcinoma	EFO_0002517	-	Table S4	DNA methylation	Pancreatic ductal adenocarcinoma	-	Beta values	-	Illumina HumanMethylation450	Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata	-	196	1	-	Missing	None	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-	-	2.94e-22	-	24500968_pancreatic_ductal_adenocarcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0797658	0.00823026	3.80823e-22	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0797366	0.00823028	3.942939e-22	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.87	0.09	4.2e-22	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-3.9	0.402	4.500000000000001e-22	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0807552	0.00835146	4.724758e-22	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0929375	0.00962035	5.160057e-22	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg04732324	chr11:68564292	11	68564292	CPT1A	Open sea	-	-	7.42e-22	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0786545	0.00823099	1.415753e-21	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Irvin MR	-	24920721	2014-08-12	Very low-density lipoprotein cholesterol	EFO_0008317	Discovery	Table 1	DNA methylation	Very low-density lipoprotein cholesterol	Age, sex and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	CD4+ T-cells	Very low-density lipoprotein cholesterol levels were log-transformed	991	1	49	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.022	0.00228	1.79e-21	-	24920721_very_lowdensity_lipoprotein_cholesterol
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.239598	0.0251949	2.141927e-21	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0961038	0.0101322	2.789166e-21	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00092	None	3e-21	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0778976	0.00823148	3.4267729999999996e-21	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0773992	0.0082318	6.104689e-21	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg19596755	chr11:68609747	11	68609747	CPT1A	North shore	-	-	6.490000000000001e-21	-	28056824_age_4_vs_age_0
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0773091	0.00823186	6.7735749999999996e-21	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0773065	0.00823186	6.793808e-21	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0772631	0.00823189	7.142871e-21	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.089562	0.00961024	1.3334579999999999e-20	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0766797	0.00823226	1.3959959999999998e-20	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-	-	1.6e-20	-	28002404_body_mass_index_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0850801	0.00915011	1.6256099999999998e-20	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0771144	0.00832308	2.214525e-20	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0865189	0.00935148	2.504956e-20	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0755821	0.00823295	4.8576949999999996e-20	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19417588	chr11:68529067	11	68529067	CPT1A	Open sea	0.0018	None	6.7e-20	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.075701	0.00828996	7.613181e-20	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.432338	0.0473795	7.946298e-20	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18262591	chr11:68579970	11	68579970	CPT1A	Open sea	0.0031	None	8e-20	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0751303	0.00823324	8.074471e-20	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.325003	0.0356314	8.224778e-20	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0922389	0.0101612	1.2494649999999998e-19	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0746941	0.00823351	1.3150629999999998e-19	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0011	None	2e-19	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.430115	0.0476893	2.090852e-19	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.100792	0.0112039	2.619302e-19	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0737939	0.00823406	3.566259e-19	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0737095	0.00823411	3.9133329999999995e-19	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0747788	0.0083764	4.874962e-19	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0841394	0.0094292	5.055869e-19	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0734366	0.00823428	5.28123e-19	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0744104	0.00835566	5.935608999999999e-19	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0744242	0.00836174	6.197796999999999e-19	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg11867574	chr11:68575227	11	68575227	CPT1A	Open sea	-0.02237	0.00228	9.5e-19	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Replication adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1955	3	61	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0104012	0.0011766	9.59e-19	-	28213390_serum_triglycerides_replication_adjusted_for_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.072867	0.00823462	9.838439e-19	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0728619	0.00823463	9.893285e-19	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0807599	0.00912725	9.896369e-19	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.072642	0.00823476	1.25626e-18	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0725612	0.00823481	1.371259e-18	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11220908	chr11:68541142	11	68541142	CPT1A	Open sea	0.0012	None	1.4e-18	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0722697	0.00823498	1.879293e-18	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0091443	0.0010457	2.24e-18	-	28213390_serum_triglycerides_discovery_adjusted_for_bmi
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-21.3	2.4	2.8e-18	-	28002404_body_mass_index_all_ancestry_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0730242	0.00836813	2.907142e-18	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0718505	0.00823523	2.950675e-18	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0717332	0.0082353	3.3459470000000002e-18	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0716829	0.00823533	3.531326e-18	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.071615	0.00823537	3.797288e-18	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0715273	0.00823542	4.170774e-18	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	0.02397	0.0025	4.6e-18	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0723469	0.00837393	6.220386e-18	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0709609	0.00823576	7.619643e-18	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0708763	0.00823581	8.334695e-18	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous decade consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	None	None	8.5e-18	None	31789449_Dugue-P-A_alcohol_consumption_previous_decade_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0708169	0.00823584	8.874801e-18	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0718541	0.00835658	8.884245e-18	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4261	5	65	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0080377	0.0009365	9.29e-18	-	28213390_serum_triglycerides_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0705862	0.00823598	1.1323980000000001e-17	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0718057	0.00838164	1.1665860000000001e-17	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Dhana K	Rotterdam study	29762635	2018-05-14	Waist Circumference	EFO_0004342	Discovery	Table 3	DNA methylation	Waist Circumference	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0005	0.000058	1.2e-17	None	29762635_Dhana-K_waist_circumference_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0703934	0.00823609	1.3872060000000001e-17	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.070224	0.00823619	1.657424e-17	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19964581	chr11:68540558	11	68540558	CPT1A	Open sea	0.0024	None	1.9e-17	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23406642	chr11:68549255	11	68549255	CPT1A	North shore	0.0018	None	2.2e-17	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0699188	0.00823637	2.281356e-17	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0697857	0.00823644	2.621161e-17	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0962376	0.011359	2.6316760000000003e-17	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.324104	0.0382908	2.7814650000000003e-17	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0777657	0.00919491	2.9878050000000004e-17	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23406642	chr11:68549255	11	68549255	CPT1A	North shore	0.00857	0.00092	3.5e-17	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0811223	0.00962229	3.7539820000000004e-17	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	0.00063	None	3.8e-17	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10703936	chr11:68549447	11	68549447	CPT1A	North shore	0.0022	None	4.6e-17	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Cardona A	FHS	31506343	2019-09-10	Type II diabetes	EFO_0001360	Replication in Europeans	Table 3	DNA methylation	Type II diabetes	Age, sex, cell composition (reference based), batch effects, body mass index	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2607	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0067	0.00079	4.8e-17	None	31506343_Cardona-A_type_ii_diabetes_replication_in_europeans
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0691178	0.00823683	5.242381000000001e-17	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Lifetime consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	None	None	5.3e-17	None	31789449_Dugue-P-A_alcohol_consumption_lifetime_consumption_discovery
Nones K	-	24500968	2014-05-09	Pancreatic ductal adenocarcinoma	EFO_0002517	-	Table S4	DNA methylation	Pancreatic ductal adenocarcinoma	-	Beta values	-	Illumina HumanMethylation450	Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata	-	196	1	-	Missing	None	cg24366211	chr11:68610706	11	68610706	CPT1A	North shore	-	-	5.55e-17	-	24500968_pancreatic_ductal_adenocarcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0763946	0.00911499	5.710292000000001e-17	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0690256	0.00823688	5.765961e-17	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Demerath EW	-	25935004	2015-08-01	Waist circumference	EFO_0004342	Discovery	Table S5	DNA methylation	Waist circumference	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	cm	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of waist circumference	2097	1	56.2	Both	African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0034	4e-04	5.79e-17	-	25935004_waist_circumference_discovery
Dhana K	Atherosclerosis Risk in Communities	29762635	2018-05-14	Waist Circumference	EFO_0004342	Replication	Table 3	DNA methylation	Waist Circumference	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	2097	1	Adults	Both	Admixed	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0034	0.00041	5.8e-17	None	29762635_Dhana-K_waist_circumference_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0688343	0.00823699	7.021515000000001e-17	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0688252	0.00823699	7.087473e-17	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0688104	0.008237	7.195972e-17	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.079291	0.00950159	7.750933000000001e-17	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0854922	0.0102525	8.17717e-17	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_4
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	None	None	8.3e-17	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Irvin MR	-	24920721	2014-08-12	Triglycerides	EFO_0004530	Discovery	Table 1	DNA methylation	Triglycerides	Age, sex and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	CD4+ T-cells	Triglycerides levels were log-transformed	991	1	49	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.035	0.00414	8.9e-17	-	24920721_triglycerides
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.068602	0.00823712	8.912813000000001e-17	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.045	0.00537	9.6e-17	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0685169	0.00823717	9.725168000000001e-17	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0796709	0.00958223	1.002276e-16	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0684765	0.00823719	1.013617e-16	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0933665	0.0112424	1.086223e-16	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0683233	0.00823728	1.185483e-16	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.098	0.0118	1.2e-16	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0774475	0.00934942	1.296916e-16	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Discovery and replication	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	979	1	48.3	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-23.86	2.84	1.39e-16	-	27777315_postprandial_lipemia_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.068155	0.00823737	1.407492e-16	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0691757	0.00836568	1.46603e-16	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_2
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for waist circumference	Table 3	DNA methylation	Triglycerides	Age, sex, smoking, waist circumference, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0114	0.0014	1.9e-16	-	28194238_triglycerides_discovery_and_replication_waist_circumference_adjusted
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg09972762	chr11:68553421	11	68553421	CPT1A	South shelf	0.01736	0.00192	1.9e-16	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0678539	0.00823754	1.911468e-16	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Aslibekyan S	-	26110892	2015-07-01	Waist circumference	EFO_0004342	Meta-analysis	Table 3	DNA methylation	Waist circumference	Age, sex, smoking, study centre and technical covariates	Beta values	cm	Illumina HumanMethylation450	CD4+ T-cells and leukocytes	-	3097	2	53.8	Both	European,African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	2.2e-16	-	26110892_waist_circumference_metaanalysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18445292	chr11:68610381	11	68610381	CPT1A	North shore	-0.0013	0.00016	2.2e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg06042565	chr11:68564477	11	68564477	CPT1A	Open sea	-0.19272	0.0235	2.27e-16	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0699365	0.00852578	2.539137e-16	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0717828	0.00875953	2.716128e-16	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0673905	0.0082378	3.05365e-16	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0672622	0.00823787	3.474529e-16	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.068057	0.00835026	3.922388e-16	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.195228	0.0240009	4.409646e-16	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0669805	0.00823803	4.609609e-16	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0774732	0.00953312	4.760315e-16	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_4
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-37.77	4.07	4.9e-16	-	28002404_body_mass_index_south_asian_ancestry_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0758969	0.00936281	5.632502e-16	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.076917	0.00949447	5.866981e-16	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20629021	chr11:68580041	11	68580041	CPT1A	Open sea	0.0011	None	6.1e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Nones K	-	24500968	2014-05-09	Pancreatic ductal adenocarcinoma	EFO_0002517	-	Table S4	DNA methylation	Pancreatic ductal adenocarcinoma	-	Beta values	-	Illumina HumanMethylation450	Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata	-	196	1	-	Missing	None	cg13786863	chr11:68610743	11	68610743	CPT1A	North shore	-	-	6.23e-16	-	24500968_pancreatic_ductal_adenocarcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0757879	0.00937194	6.607932e-16	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20285002	chr11:68583898	11	68583898	CPT1A	Open sea	-0.0006	0.000074	6.7e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg13786863	chr11:68610743	11	68610743	CPT1A	North shore	-	-	6.83e-16	-	23526956_clear_cell_renal_carcinoma
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4261	5	65	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0079	0.001	7.23e-16	-	28213390_serum_triglycerides_discovery_and_replication_adjusted_for_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	-0.0665276	0.00823828	7.243876e-16	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0832358	0.0103107	7.402619e-16	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_4
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-3.6	0.446	7.5e-16	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Replication	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1955	3	61	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0134246	0.0016653	7.55e-16	-	28213390_serum_triglycerides_replication
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.383271	0.0475384	7.969397e-16	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0679599	0.00843538	8.450715e-16	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0663096	0.0082384	8.995059e-16	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for other lipids	Table 3	DNA methylation	Triglycerides	Age, sex, smoking, other lipids, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0196	0.0024	9.2e-16	-	28194238_triglycerides_discovery_and_replication_other_lipids_adjusted
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0688827	0.00856386	9.401611e-16	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0661991	0.00823846	0.000000000000001003667	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0741234	0.00922869	0.000000000000001032947	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0763246	0.00950916	0.000000000000001079377	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0726645	0.00905925	0.000000000000001127521	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_3
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery	Table 2	DNA methylation	Triglycerides	Age, sex, smoking, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	725	1	60	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0206	0.0026	0.00000000000000123	-	28194238_triglycerides_discovery
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting insulin	EFO_0004466	Base	Supplementary Data 1	DNA methylation	fasting insulin	Age, sex, smoking, cell composition (reference based), batch effects	Beta Values	log pmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-3.12	0.39	0.0000000000000013	4739	31197173_Liu-J_fasting_insulin_base
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04732324	chr11:68564292	11	68564292	CPT1A	Open sea	0.0014	None	0.0000000000000013	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0735668	0.00919951	0.000000000000001371728	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg13786863	chr11:68610743	11	68610743	CPT1A	North shore	-0.019	0.00196	0.0000000000000014	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.065844	0.00823865	0.000000000000001425127	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0656651	0.00822664	0.000000000000001545943	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0656978	0.00823873	0.000000000000001645501	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Mamtani M	-	26798409	2016-01-20	Hypertriglyceridemic waist	EFO_0004342, EFO_0004530	-	Table S2	Liability function of hypertriglyceridemic waist	DNA methylation	Age, sex, use of statin, use of anti-hypertensive, use of diabetic medications, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	-	850	1	46.8	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.4826574	0.06064	0.00000000000000173	-	26798409_hypertriglyceridemic_waist
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0657758	0.00826927	0.000000000000001933286	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.00086826	0.0001077	0.000000000000002	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0674824	0.00848886	0.000000000000002008116	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0755163	0.00950279	0.000000000000002053546	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0729851	0.00919487	0.000000000000002210095	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0653783	0.00823891	0.00000000000000225085	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0662125	0.0083469	0.000000000000002300772	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0761477	0.00960255	0.000000000000002350006	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0827935	0.0104491	0.000000000000002475108	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0671291	0.00848826	0.000000000000002790874	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0732889	0.00927464	0.000000000000002937173	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	M-VLDL-PL_pct	None	Meta-analysis	Table S2	DNA methylation	M-VLDL-PL_pct	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	%	Illumina HumanMethylation450	Whole blood	Phospholipids to total lipids ratio in medium VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.36	0.046	0.0000000000000032	None	33413638_Gomez-Alonso-MDC_m-vldl-pl_pct_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10553894	chr11:68550534	11	68550534	CPT1A	Island	-0.00089	0.00011	0.0000000000000033	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Irvin MR	-	24920721	2014-08-12	Very low-density lipoprotein cholesterol	EFO_0008317	Discovery	Table 1	DNA methylation	Very low-density lipoprotein cholesterol	Age, sex and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	CD4+ T-cells	Very low-density lipoprotein cholesterol levels were log-transformed	991	1	49	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.025	0.00315	0.00000000000000332	-	24920721_very_lowdensity_lipoprotein_cholesterol
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0649143	0.00823916	0.000000000000003537689	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0648759	0.00823918	0.000000000000003672238	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0648236	0.00823921	0.00000000000000386331	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0657769	0.00836815	0.000000000000004095022	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0875747	0.011142	0.000000000000004111852	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0657543	0.0083712	0.000000000000004280179	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10703936	chr11:68549447	11	68549447	CPT1A	North shore	-0.013	0.0016	0.0000000000000044	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19417588	chr11:68529067	11	68529067	CPT1A	Open sea	0.006	None	0.0000000000000044	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0646175	0.00823932	0.000000000000004716705	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.064547	0.00823935	0.000000000000005049021	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Bozack	PRISM	34569420	Oct 22, 2021	Infant sex	PATO_0001894	Umbilical artery	Supplementary table 10	DNA methylation	Infant sex	Cell composition (reference free), Batch effects, Ancestry (other)	M values	None	Illumina HumanMethylation450	Umbilical artery	None	229	1	Infants	Both	European, African, Other	cg24366211	chr11:68610706	11	68610706	CPT1A	North shore	None	None	0.0000000000000056	None	34569420_Bozack_infant_sex_umbilical_artery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.089237	0.0114239	0.000000000000006035831	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_4
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-	-	0.00000000000000611	-	26857698_primary_sjogrens_syndrome_whole_blood
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0011	0.00014	0.0000000000000062	None	29762635_Dhana-K_body_mass_index_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0642862	0.00823949	0.000000000000006492135	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0716383	0.00918824	0.000000000000006778751	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08723623	chr11:68541465	11	68541465	CPT1A	Open sea	0.01361	0.00162	0.0000000000000082	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26906629	chr11:68564367	11	68564367	CPT1A	Open sea	0.00051	None	0.0000000000000084	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12031060	chr11:68550320	11	68550320	CPT1A	Island	-0.0640088	0.00823964	0.000000000000008473374	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0650263	0.00837161	0.000000000000008535285	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0716451	0.00925121	0.00000000000001022937	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0638075	0.00823975	0.00000000000001027279	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0710464	0.00918196	0.00000000000001078877	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0637075	0.0082398	0.00000000000001130081	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Replication	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	326	1	48.8	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-50.84	6.27	0.0000000000000118	-	27777315_postprandial_lipemia_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0636552	0.00823983	0.00000000000001187804	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0635107	0.0082399	0.00000000000001362953	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.275187	0.0357375	0.00000000000001431305	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0732709	0.00951641	0.00000000000001453963	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0871381	0.0113276	0.00000000000001533836	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0705721	0.00917715	0.00000000000001564894	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0631858	0.00824007	0.00000000000001854808	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0631606	0.00824009	0.00000000000001899493	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0705315	0.00920862	0.00000000000001986204	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0630764	0.00824013	0.00000000000002056916	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0630392	0.00824015	0.00000000000002130353	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting glucose	EFO_0004465	Base	Supplementary Data 1	DNA methylation	fasting glucose	Age, sex, smoking, cell composition (reference based), batch effects	Beta Values	mmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-2.67	0.35	0.000000000000025	4807	31197173_Liu-J_fasting_glucose_base
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.347903	0.0457205	0.00000000000002889075	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0596855	0.0078456	0.00000000000002963873	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0626837	0.00824033	0.00000000000002976793	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.086131	0.0113292	0.00000000000003078688	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.463253	0.0609473	0.00000000000003084063	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0626328	0.00824036	0.00000000000003122505	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0626162	0.00824037	0.00000000000003171604	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0644977	0.00850407	0.00000000000003542362	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0624898	0.00824043	0.00000000000003570187	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0624069	0.00824048	0.00000000000003857961	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0623786	0.00824049	0.00000000000003961216	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12691334	chr11:68610186	11	68610186	CPT1A	North shore	0.011	0.0014	0.000000000000044	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	0.02084	0.0028	0.000000000000045	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0694831	0.00920448	0.0000000000000464992	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0621337	0.00824062	0.00000000000004977312	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0619703	0.0082407	0.00000000000005793435	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0693341	0.00923423	0.00000000000006330717	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0713007	0.00950096	0.00000000000006516297	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0696428	0.00928174	0.00000000000006585043	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Petersen A-K	KORA F4	24014485	2013-09-06	M33871_1-eicosadienoylglycerophosphocholine*	EFO_0004727, EFO_0004725	no snps model	Table S2	M33871_1-eicosadienoylglycerophosphocholine*	DNA methylation	Age, sex, body mass index, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1760	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-1	0.51	0.000000000000068	None	24014485_Petersen-A-K_m33871_1-eicosadienoylglycerophosphocholine__no_snps_model
Aslibekyan S	-	28139377	2016-11-23	Plasma adiponectin	EFO_0004502	Discovery adjusted for smoking and alcohol consumption	Table 4	DNA methylation	Plasma adiponectin	Age, sex, smoking, alcohol consumption and technical covariates	Beta values	ug/dl	Illumina HumanMethylation450	CD4+ T-cells	Plasma adiponectin levels were log transformed	991	1	49	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.01	0.001	0.000000000000074	-	28139377_plasma_adiponectin_discovery_adjusted_for_smoking_and_alcohol
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0616963	0.00824084	0.00000000000007467336	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0704957	0.00941788	0.00000000000007544185	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0715479	0.00958436	0.00000000000008793721	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0635435	0.00851754	0.00000000000009115666	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Petersen A-K	KORA F4	24014485	2013-09-06	M33871_1-eicosadienoylglycerophosphocholine*	EFO_0004727, EFO_0004725	snps as covariates model	Table S4	M33871_1-eicosadienoylglycerophosphocholine*	DNA methylation	Age, sex, body mass index, cell composition (reference based), genotype	None	Beta Values	Illumina HumanMethylation450	Whole blood	used three nearby snps as covariates	1760	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-1	0.51	0.000000000000092	None	24014485_Petersen-A-K_m33871_1-eicosadienoylglycerophosphocholine__snps_as_covariates_model
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Lifetime consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	None	None	0.000000000000096	None	31789449_Dugue-P-A_alcohol_consumption_lifetime_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0613928	0.008241	0.00000000000009877808	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0613688	0.00824101	0.0000000000001009858	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0613474	0.00824102	0.0000000000001029946	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0613371	0.00824103	0.0000000000001039728	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0613237	0.00824103	0.0000000000001052612	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.061181	0.0082411	0.00000000000011998	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Richard MA	CHARGE	29198723	2019-11-25	Systolic Blood Pressure	EFO_0006335	Meta-analysis	Table S4	DNA methylation	Systolic Blood Pressure	Age, sex, smoking, batch effects, ancestry, body mass index, blood cell counts	Beta Values	mmHg	Illumina HumanMethylation450	Whole blood, CD4+ T cells	Overall meta-analysis of discovery and replication cohorts	17010	14	Adults	Both	African, Admixed, European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00005	None	0.00000000000012	None	29198723_Richard-MA_systolic_blood_pressure_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03855388	chr11:68580018	11	68580018	CPT1A	Open sea	0.00028	None	0.00000000000012	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.069683	0.00939647	0.0000000000001274412	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14443077	chr11:68606701	11	68606701	CPT1A	Island	0.00066	None	0.00000000000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0621311	0.00838205	0.0000000000001308076	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.061084	0.00824115	0.0000000000001311291	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0620801	0.00838225	0.0000000000001371188	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0610135	0.00824119	0.0000000000001398697	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0681273	0.00920531	0.0000000000001426445	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0632392	0.0085518	0.0000000000001492473	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0608467	0.00824127	0.0000000000001628743	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0607926	0.0082413	0.0000000000001711139	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0682785	0.00928119	0.0000000000001985701	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0606235	0.00824139	0.0000000000001995641	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23406642	chr11:68549255	11	68549255	CPT1A	North shore	0.0058	None	0.0000000000002	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.052	0.00618	0.00000000000021	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0669739	0.00911434	0.0000000000002115012	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0605237	0.00824144	0.0000000000002184813	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0604661	0.00824146	0.000000000000230203	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10703936	chr11:68549447	11	68549447	CPT1A	North shore	0.0073	None	0.00000000000025	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11867574	chr11:68575227	11	68575227	CPT1A	Open sea	0.0014	None	0.00000000000025	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-18.44	2.52	0.00000000000027	-	28002404_body_mass_index_european_ancestry_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0685619	0.00937689	0.0000000000002772307	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_2
Fernández-Sanlés A.	REGICOR, Framingham Offspring Cohort	29326313	2018-01-11	Cardiovascular risk	EFO_0003919, EFO_0004298	Age-independent cardiovascular risk was determined via the delta age approach, results meta-analysesd across discovery and replicaton cohorts	Table 2	DNA methylation	Cardiovascular risk	Sex, age, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole Blood	None	2746	2	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0182	0.0025	0.00000000000028	None	29326313_Fernández-Sanlés-A._cardiovascular_risk_age-independent_cardiovascular_risk_was_determined_via_the_delta_age_approach__results_meta-analysesd_across_discovery_and_replicaton_cohorts
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0602018	0.0082416	0.0000000000002923598	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_1
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for lipid-lowering medication use	Table 3	DNA methylation	Triglycerides	Age, sex, smoking, lipid-lowering medication use, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0146	0.002	0.00000000000031	-	28194238_triglycerides_discovery_and_replication_lipidlowering_medication_use_adjusted
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0698952	0.00957952	0.0000000000003109372	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Pfeiffer L	-	25583993	2015-01-12	Triglycerides	EFO_0004530, CHEBI_17855	Discovery	Table 2	Triglycerides	DNA methylation	Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts	mg/dl	Beta values	Illumina HumanMethylation450	Whole blood	-	1776	1	61	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.118	0.016	0.000000000000315	-	25583993_triglycerides_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0611433	0.00838945	0.0000000000003303454	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0827377	0.011354	0.0000000000003328153	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_4
Aslibekyan S	-	28139377	2016-11-14	Plasma adiponectin	EFO_0004502	Discovery	Table 2	DNA methylation	Plasma adiponectin	Age, sex and technical covariates	Beta values	ug/dl	Illumina HumanMethylation450	CD4+ T-cells	Plasma adiponectin levels were log transformed	991	1	49	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.01	0.001	0.00000000000034	-	28139377_plasma_adiponectin_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.18831	0.0258666	0.0000000000003475119	None	39706196_Hannah-M.-Smith_glucose_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0599811	0.00824171	0.0000000000003566501	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0599722	0.00824171	0.0000000000003595021	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0681375	0.00936492	0.0000000000003617564	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0610008	0.00839033	0.000000000000376616	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_2
Petersen A-K	KORA F4	24014485	2013-09-06	M32397_3-hydroxy-2-ethylpropionate	EFO_0004727, EFO_0004725	snps as covariates model	Table S4	M32397_3-hydroxy-2-ethylpropionate	DNA methylation	Age, sex, body mass index, cell composition (reference based), genotype	None	Beta Values	Illumina HumanMethylation450	Whole blood	used three nearby snps as covariates	1760	1	Adults	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	3.8	0.093	0.00000000000039	None	24014485_Petersen-A-K_m32397_3-hydroxy-2-ethylpropionate_snps_as_covariates_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.206028	0.0283764	0.0000000000004010302	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.291186	0.0401104	0.0000000000004046902	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0741168	0.0102085	0.0000000000004056844	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03855388	chr11:68580018	11	68580018	CPT1A	Open sea	0.00098	None	0.00000000000043	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.067874	0.00937001	0.0000000000004581929	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0596941	0.00824185	0.0000000000004613835	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0683568	0.00944374	0.0000000000004768632	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_3
Liu C	CHARGE+	27843151	2016-12-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	European ancestry	Table S5	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g der day	Illumina HumanMethylation450	Whole blood	-	9643	10	64.2	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.00016211	2.24e-05	0.000000000000503	-	27843151_alcohol_consumption_per_day_european_ancestry
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0595842	0.0082419	0.0000000000005089985	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0595792	0.0082419	0.0000000000005112711	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0595653	0.00824191	0.0000000000005176695	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	None	None	0.00000000000052	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0663836	0.00918844	0.0000000000005270141	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg20629021	chr11:68580041	11	68580041	CPT1A	Open sea	-0.16458	0.0228	0.000000000000555	-	25650246_gestational_age
Justice AE	ARIC study	32901515	09-09-2020	waist circumference-to-hip ratio	None	discovery	Table 1	waist circumference-to-hip ratio	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Body mass index, Education	cm	Beta values	Illumina HumanMethylation450	Whole blood	None	2684	1	Adults	Both	African, Other	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.44	0.061	0.00000000000058	None	32901515_Justice-AE_waist_circumference-to-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0680831	0.00944171	0.0000000000005831261	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0662782	0.00919324	0.0000000000005892449	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0741739	0.0102897	0.0000000000005931968	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09972762	chr11:68553421	11	68553421	CPT1A	South shelf	0.0028	None	0.00000000000062	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0592971	0.00824204	0.0000000000006574312	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27175470	chr11:68575176	11	68575176	CPT1A	Open sea	0.0053	None	0.00000000000067	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0659125	0.00917704	0.000000000000718375	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_2
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Replication	Table 2	DNA methylation	Triglycerides	Age, sex, smoking, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	760	1	68	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0114	0.0016	0.000000000000724	-	28194238_triglycerides_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0663484	0.00924031	0.0000000000007288939	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0811429	0.0113216	0.0000000000008027579	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.059058	0.00824216	0.000000000000812846	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0590369	0.00824217	0.0000000000008281311	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.059032	0.00824217	0.0000000000008317474	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14247222	chr11:68549334	11	68549334	CPT1A	North shore	0.0033	None	0.00000000000084	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Liu C	CHARGE+	27843151	2016-12-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	European ancestry	Table S5	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g der day	Illumina HumanMethylation450	Whole blood	-	9643	10	64.2	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.00016189	2.26e-05	0.00000000000085	-	27843151_alcohol_consumption_per_day_european_ancestry
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0662307	0.00925676	0.0000000000008773837	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_3
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Replication adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1955	3	61	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0124776	0.0017461	0.000000000000893	-	28213390_serum_triglycerides_replication_adjusted_for_bmi
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg18262591	chr11:68579970	11	68579970	CPT1A	Open sea	-0.06947	0.0097	0.000000000000918	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0587827	0.00824229	0.000000000001036717	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0677451	0.00950396	0.000000000001065291	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0586658	0.00824235	0.000000000001149082	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0683916	0.00960889	0.000000000001149767	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.00049918	6.93e-05	0.00000000000116	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg26906629	chr11:68564367	11	68564367	CPT1A	Open sea	-0.21118	0.0297	0.00000000000122	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0595153	0.00837706	0.000000000001262768	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0085	0.0012	0.0000000000013	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0744313	0.0104901	0.000000000001349173	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.21814	0.0308	0.00000000000136	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0667873	0.00942373	0.000000000001431649	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0640511	0.00904551	0.000000000001496417	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication	Table S1	DNA methylation	Triglycerides	Age, sex, smoking, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.014	0.002	0.00000000000153	-	28194238_triglycerides_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0770187	0.0108889	0.000000000001583353	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.05828	0.00824254	0.000000000001611973	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0582684	0.00824254	0.000000000001628341	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Lifetime consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	None	None	0.0000000000017	None	31789449_Dugue-P-A_alcohol_consumption_lifetime_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0663961	0.00940704	0.000000000001763359	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0581293	0.00824261	0.000000000001838686	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.058103	0.00824262	0.000000000001881193	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0661198	0.00938158	0.000000000001898389	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0580922	0.00824263	0.000000000001899146	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0046	0.00058	0.0000000000019	None	33564054_Kashima-K_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.065909	0.00935291	0.000000000001911107	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0580389	0.00824265	0.000000000001989348	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04732324	chr11:68564292	11	68564292	CPT1A	Open sea	0.00038	None	0.000000000002	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10132543	chr11:68609520	11	68609520	CPT1A	North shore	0.00022	0.000032	0.000000000002	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0579246	0.00824271	0.000000000002197369	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0656604	0.00934371	0.000000000002199668	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Bozack	PRISM	34569420	Oct 22, 2021	Infant sex	PATO_0001894	Umbilical artery	Supplementary table 10	DNA methylation	Infant sex	Cell composition (reference free), Batch effects, Ancestry (other)	M values	None	Illumina HumanMethylation450	Umbilical artery	None	229	1	Infants	Both	European, African, Other	cg25890640	chr11:68610632	11	68610632	CPT1A	North shore	None	None	0.0000000000023	None	34569420_Bozack_infant_sex_umbilical_artery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0781999	0.0111615	0.000000000002555299	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	0.00052	0.000074	0.0000000000027	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.059757	0.00853885	0.000000000002704162	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-18.2	2.4	0.0000000000028	-	28002404_body_mass_index_all_ancestry_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0576363	0.00824285	0.000000000002821448	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.279768	0.0400232	0.000000000002846627	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0595561	0.00852237	0.000000000002904242	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0583612	0.00835229	0.000000000002919972	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.078543	0.0112545	0.000000000003104825	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0585007	0.00838507	0.00000000000314979	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_2
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg03855388	chr11:68580018	11	68580018	CPT1A	Open sea	-0.12941	0.0186	0.00000000000318	-	25650246_gestational_age
Dhana K	Atherosclerosis Risk in Communities	29762635	2018-05-14	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	2097	1	Adults	Both	Admixed	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0029	0.00042	0.0000000000032	None	29762635_Dhana-K_body_mass_index_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0029	4e-04	0.00000000000323	-	25935004_body_mass_index_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0574794	0.00824292	0.000000000003230775	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0651691	0.00935809	0.000000000003449949	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0788602	0.0113291	0.00000000000352569	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0644916	0.00927588	0.000000000003737166	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_3
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg10257063	chr11:68587159	11	68587159	CPT1A	Open sea	0.034	0.00431	0.0000000000039	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.064276	0.0092566	0.000000000003977337	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	-0.00049	0.000071	0.0000000000041	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	0.300157	0.0432648	0.00000000000412044	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.267333	0.0385653	0.000000000004296847	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0571434	0.00824308	0.000000000004313818	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0637764	0.00920049	0.000000000004327176	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0579408	0.00836123	0.000000000004393501	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0650816	0.00939199	0.000000000004399815	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.086	0.0124	0.0000000000044	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0641794	0.00926656	0.000000000004512095	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0570459	0.00824313	0.000000000004689579	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0783917	0.0113286	0.000000000004709871	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0579898	0.00838577	0.000000000004862993	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13491471	chr11:68575385	11	68575385	CPT1A	Open sea	-0.00041	0.000059	0.0000000000051	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.056947	0.00824317	0.000000000005104068	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous decade consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	None	None	0.0000000000054	None	31789449_Dugue-P-A_alcohol_consumption_previous_decade_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0644656	0.00934942	0.000000000005601017	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	-0.0568305	0.00824323	0.000000000005637791	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0648121	0.0094174	0.000000000006133991	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0566968	0.00824329	0.000000000006318558	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0566941	0.00824329	0.000000000006332917	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.044	0.00565	0.0000000000068	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0631405	0.00919579	0.000000000006856664	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0564681	0.0082434	0.000000000007673598	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0564417	0.00824341	0.000000000007846944	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0640523	0.00936548	0.000000000008279656	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0563566	0.00824345	0.000000000008433597	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0563541	0.00824345	0.000000000008451676	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.071087	0.0103993	0.000000000008480203	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0629116	0.00921544	0.000000000009026361	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0627676	0.00920639	0.000000000009603875	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0569031	0.00837301	0.00000000001116954	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0560182	0.00824361	0.00000000001122141	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0641271	0.00943758	0.00000000001125994	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	-0.423407	0.0625145	0.0000000000130255	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0645344	0.00952856	0.00000000001311907	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0557924	0.00824371	0.00000000001356404	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0622925	0.00920633	0.000000000013715	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0557642	0.00824372	0.00000000001388828	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0564667	0.00835405	0.00000000001439939	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0556576	0.00824377	0.00000000001518488	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	0.0653608	0.00970619	0.0000000000171281	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0623233	0.0092557	0.00000000001717862	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0555068	0.00824384	0.00000000001722347	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0628007	0.00933365	0.00000000001778846	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0561892	0.00836249	0.00000000001894782	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00095	0.00014	0.000000000019	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0553648	0.00824391	0.00000000001938544	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Liu C	CHARGE+	27843151	2016-12-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	European ancestry	Table S5	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g der day	Illumina HumanMethylation450	Whole blood	-	9643	10	64.2	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00010127	1.51e-05	0.0000000000209	-	27843151_alcohol_consumption_per_day_european_ancestry
Bozack	PRISM	34569420	Oct 22, 2021	Infant sex	PATO_0001894	Umbilical artery	Supplementary table 10	DNA methylation	Infant sex	Cell composition (reference free), Batch effects, Ancestry (other)	M values	None	Illumina HumanMethylation450	Umbilical artery	None	229	1	Infants	Both	European, African, Other	cg13786863	chr11:68610743	11	68610743	CPT1A	North shore	None	None	0.000000000021	None	34569420_Bozack_infant_sex_umbilical_artery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0552666	0.00824395	0.00000000002103481	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0760018	0.0113412	0.00000000002139584	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0552085	0.00824398	0.00000000002207327	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0552012	0.00824398	0.00000000002220835	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0551734	0.00824399	0.0000000000227255	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Justice AE	ARIC study	32901515	09-09-2020	waist circumference-to-height	None	discovery	Table 1	waist circumference-to-height	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Body mass index, Education	cm	Beta values	Illumina HumanMethylation450	Whole blood	None	2684	1	Adults	Both	African, Other	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.267	0.04	0.000000000023	None	32901515_Justice-AE_waist_circumference-to-height_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20201954	chr11:68609518	11	68609518	CPT1A	North shore	-0.0001	0.000015	0.000000000023	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0550858	0.00824403	0.00000000002443757	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0625803	0.00936679	0.00000000002457337	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0625339	0.00936547	0.00000000002525429	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.175378	0.0263104	0.00000000002713122	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0607421	0.00911173	0.0000000000271593	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0549513	0.0082441	0.00000000002731169	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0614542	0.009223	0.00000000002775912	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.414628	0.0622954	0.00000000002901556	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12031060	chr11:68550320	11	68550320	CPT1A	Island	-0.0548573	0.00824414	0.0000000000295155	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Ma J	FHS, RS, CARDIA, MESA	30936141	2020-05-22	Hepatic Fat	EFO_0006506, EFO_0008421	Meta-analysis model 1	Table 1	DNA methylation	Hepatic Fat	Age, sex	Beta Values	Hounsfield units	Illumina HumanMethylation450	Whole blood	Model 1 = adjusted for sex + age	3400	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	None	None	0.00000000003	None	30936141_Ma-J_hepatic_fat_meta-analysis_model_1
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Discovery	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	653	1	48	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-33.24	4.91	0.0000000000302	-	27777315_postprandial_lipemia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0547973	0.00824417	0.00000000003101042	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0621924	0.00936054	0.00000000003158402	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0564091	0.0084939	0.00000000003222368	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04732324	chr11:68564292	11	68564292	CPT1A	Open sea	-0.00034	0.000051	0.000000000033	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0546988	0.00824421	0.00000000003363012	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0546527	0.00824423	0.00000000003492909	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0610415	0.00921713	0.00000000003651911	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous decade consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	None	None	0.000000000037	None	31789449_Dugue-P-A_alcohol_consumption_previous_decade_consumption_discovery
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg10132543	chr11:68609520	11	68609520	CPT1A	North shore	0.01042	0.0016	0.0000000000375	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0612474	0.00925381	0.00000000003751566	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0545576	0.00824427	0.00000000003776642	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0545497	0.00824428	0.00000000003801204	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0545352	0.00824428	0.00000000003846475	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Hedman AK	-	28213390	2017-02-17	Serum total cholesterol	EFO_0004574	Discovery and replication adjusted for BMI	Table S6	DNA methylation	Serum total cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4331	5	65	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-9.15e-05	1.39e-05	0.0000000000386	-	28213390_serum_total_cholesterol_discovery_and_replication_adjusted_for_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0607194	0.00918102	0.00000000003881133	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0685221	0.0103671	0.00000000003988189	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0553293	0.00837461	0.00000000004062675	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0544301	0.00824433	0.00000000004192408	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Hedman AK	-	28213390	2017-02-17	Serum total cholesterol	EFO_0004574	Discovery and replication	Table S2	DNA methylation	Serum total cholesterol	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Inverse variance weighted fixed-effect meta-analysis	4331	5	65	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-9.13e-05	1.38e-05	0.0000000000425	-	28213390_serum_total_cholesterol_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0543546	0.00824437	0.00000000004459314	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0543231	0.00824438	0.00000000004575787	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0551568	0.00837772	0.0000000000474308	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0606781	0.0092211	0.00000000004852786	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0964252	0.0146556	0.00000000004883833	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	-0.254707	0.0387207	0.00000000004902399	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0542197	0.00824443	0.00000000004978348	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_1
Nones K	-	24500968	2014-05-09	Pancreatic ductal adenocarcinoma	EFO_0002517	-	Table S4	DNA methylation	Pancreatic ductal adenocarcinoma	-	Beta values	-	Illumina HumanMethylation450	Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata	-	196	1	-	Missing	None	cg18445292	chr11:68610381	11	68610381	CPT1A	North shore	-	-	0.0000000000498	-	24500968_pancreatic_ductal_adenocarcinoma
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	2.3	0.352	0.000000000051	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0619158	0.00941986	0.00000000005101142	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0605424	0.00921272	0.00000000005145499	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.054168	0.00824445	0.00000000005192934	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.061572	0.00937143	0.00000000005194834	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0614646	0.00935673	0.00000000005234955	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_2
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.035	0.00476	0.000000000053	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0541426	0.00824446	0.00000000005301447	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	sensitivity	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.189423	0.0288687	0.00000000005471482	None	39706196_Hannah-M.-Smith_glucose_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0613047	0.00934477	0.00000000005549046	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0603708	0.0092205	0.00000000006047098	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0627565	0.00958764	0.00000000006124409	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0539603	0.00824454	0.00000000006148319	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	-0.014	0.00189	0.000000000062	None	32795589_Kyung-WK_atopy_discovery
Ma J	FHS, RS, CARDIA, MESA	30936141	2020-05-22	Hepatic Fat	EFO_0006506, EFO_0008421	Meta-analysis model 2	Table 1	DNA methylation	Hepatic Fat	Age, sex	Beta Values	Hounsfield units	Illumina HumanMethylation450	Whole blood	Model 2 = model 1 + smoking + physical activity + alcohol consumption	3400	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	None	None	0.000000000063	None	30936141_Ma-J_hepatic_fat_meta-analysis_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0620451	0.00950108	0.0000000000677935	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0609336	0.00934338	0.00000000007184791	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_2
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Discovery GOLDN	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells	-	991	1	49	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-9e-04	1e-04	0.000000000076	-	26110892_body_mass_index_discovery_goldn
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0971277	0.0149212	0.00000000007791809	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0536482	0.00824468	0.00000000007915115	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0624192	0.0095993	0.00000000008156572	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0618098	0.00950735	0.00000000008222321	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05710301	chr11:68540704	11	68540704	CPT1A	Open sea	0.0055	None	0.000000000083	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mamtani M	-	26798409	2016-01-20	Hypertriglyceridemic waist	EFO_0004342, EFO_0004530	-	Table S2	Liability function of hypertriglyceridemic waist	DNA methylation	Age, sex, use of statin, use of anti-hypertensive, use of diabetic medications, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	-	850	1	46.8	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.4387933	0.06762	0.0000000000865	-	26798409_hypertriglyceridemic_waist
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0535289	0.00824473	0.00000000008714132	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Irvin MR	-	24920721	2014-08-12	Triglycerides	EFO_0004530	Discovery	Table 1	DNA methylation	Triglycerides	Age, sex and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	CD4+ T-cells	Triglycerides levels were log-transformed	991	1	49	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.011	0.00163	0.0000000000879	-	24920721_triglycerides
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	M-VLDL-C_pct	None	Meta-analysis	Table S2	DNA methylation	M-VLDL-C_pct	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	%	Illumina HumanMethylation450	Whole blood	Total cholesterol to total lipids ratio in medium VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	1.2	0.18	0.000000000091	None	33413638_Gomez-Alonso-MDC_m-vldl-c_pct_meta-analysis
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0071536	0.0011038	0.0000000000913	-	28213390_serum_triglycerides_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0534155	0.00824478	0.00000000009546291	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Replication	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	326	1	48.8	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-33.53	5.01	0.000000000101	-	27777315_postprandial_lipemia_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	0.0623421	0.00963871	0.000000000102527	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Irvin MR	-	24920721	2014-08-12	Very low-density lipoprotein cholesterol	EFO_0008317	Discovery	Table 1	DNA methylation	Very low-density lipoprotein cholesterol	Age, sex and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	CD4+ T-cells	Very low-density lipoprotein cholesterol levels were log-transformed	991	1	49	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.008	0.00124	0.000000000106	-	24920721_very_lowdensity_lipoprotein_cholesterol
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0659098	0.0101989	0.0000000001062668	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01260103	chr11:68609203	11	68609203	CPT1A	Island	-0.00007	0.000011	0.00000000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0605582	0.00939541	0.0000000001188122	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0548645	0.00851355	0.0000000001197014	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0593126	0.00920384	0.0000000001197424	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.033	0.00512	0.00000000012	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	1.8	0.274	0.00000000012	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.172348	0.0267514	0.0000000001205621	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0530933	0.00824493	0.0000000001235875	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0614868	0.00955596	0.0000000001278278	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0530261	0.00824496	0.0000000001304002	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0538293	0.00837456	0.0000000001335376	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0529898	0.00824497	0.0000000001342359	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.154595	0.024068	0.0000000001366959	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.034	0.0047	0.00000000014	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0729407	0.0113718	0.0000000001459475	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.0528476	0.00824503	0.0000000001503273	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0561278	0.00875696	0.0000000001504529	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-28.75	3.95	0.00000000016	-	28002404_body_mass_index_south_asian_ancestry_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26906629	chr11:68564367	11	68564367	CPT1A	Open sea	-0.00038	0.000059	0.00000000016	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0600613	0.0093861	0.0000000001611907	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0527415	0.00824508	0.0000000001635518	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0590919	0.00923944	0.0000000001647481	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0722767	0.0113315	0.0000000001843175	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0525697	0.00824515	0.0000000001874164	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.088	0.0138	0.00000000019	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23406642	chr11:68549255	11	68549255	CPT1A	North shore	-0.0085	0.0013	0.00000000019	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0586466	0.00920489	0.0000000001930932	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0525273	0.00824517	0.0000000001938205	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.053963	0.00847122	0.0000000001944715	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0541148	0.00849881	0.0000000001980573	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0612215	0.00962086	0.000000000203184	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.169716	0.0266768	0.0000000002042233	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0524394	0.00824521	0.0000000002077518	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.052438	0.00824521	0.0000000002079922	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0524354	0.00824521	0.0000000002084196	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting insulin	EFO_0004466	Base	Supplementary Data 1	DNA methylation	fasting insulin	Age, sex, smoking, cell composition (reference based), batch effects	Beta Values	log pmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-1.78	0.28	0.00000000021	4740	31197173_Liu-J_fasting_insulin_base
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	-0.245542	0.0386354	0.0000000002131215	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0523181	0.00824526	0.0000000002286204	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0523058	0.00824527	0.0000000002308409	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	0.052223	0.0082453	0.0000000002463853	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg10970946	chr11:68540864	11	68540864	CPT1A	Open sea	-0.01099	0.0017	0.000000000254	-	23334450_rheumatoid_arthritis
Aslibekyan S	-	26110892	2015-07-01	Waist circumference	EFO_0004342	Discovery GOLDN	Table 3	DNA methylation	Waist circumference	Age, sex, smoking, study centre and technical covariates	Beta values	cm	Illumina HumanMethylation450	CD4+ T-cells	-	991	1	49	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-3e-04	5e-05	0.00000000026	-	26110892_waist_circumference_discovery_goldn
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0528889	0.00836552	0.0000000002652528	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0521151	0.00824535	0.0000000002681707	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0520976	0.00824536	0.0000000002718923	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0583209	0.00924028	0.0000000002841222	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0591287	0.00937222	0.000000000289036	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Richard MA	CHARGE	29198723	2019-11-25	Diastolic Blood Pressure	EFO_0006336	Meta-analysis	Table S4	DNA methylation	Diastolic Blood Pressure	Age, sex, smoking, batch effects, ancestry, body mass index, blood cell counts	Beta Values	mmHg	Illumina HumanMethylation450	Whole blood, CD4+ T cells	Overall meta-analysis of discovery and replication cohorts	17010	14	Adults	Both	African, Admixed, European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.000075	None	0.0000000003	None	29198723_Richard-MA_diastolic_blood_pressure_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0527719	0.00837571	0.0000000003049863	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0519129	0.00824544	0.0000000003142157	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.166087	0.0263949	0.0000000003201038	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0604701	0.00960991	0.0000000003213162	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.05838	0.00927975	0.0000000003241266	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0536551	0.00853087	0.0000000003274799	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0613685	0.00975823	0.0000000003287895	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Jiantao Ma	FHS	30796027	Feb 22, 2019	hepatic fat	EFO_0010821	Discovery	Table 1	DNA methylation	hepatic fat	Age, Sex, Cell composition (reference based), Batch effects	Beta values	None	Illumina HumanMethylation450	whole blood	None	1496	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	None	None	0.00000000033	None	30796027_Jiantao-Ma_hepatic_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0515537	0.0081993	0.0000000003315984	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0518228	0.00824548	0.0000000003371286	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0634559	0.0100996	0.0000000003414531	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0652803	0.0103906	0.0000000003423402	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0517824	0.00824549	0.0000000003479339	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13971	1	Adults (18-65y)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.039	0.00627	0.00000000035	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0517555	0.00824551	0.0000000003552895	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0570396	0.00909559	0.0000000003684874	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	2.9	0.457	0.00000000037	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg25464950	chr11:68600521	11	68600521	CPT1A	Open sea	-0.357277	0.0570044	0.0000000003754787	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0581848	0.00929346	0.0000000003935903	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.176779	0.0282611	0.0000000004058654	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0593341	0.00949056	0.000000000416717	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	0.00064	None	0.00000000042	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0594212	0.00951953	0.0000000004438201	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0585129	0.00937896	0.0000000004532199	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0514311	0.00824564	0.0000000004571892	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0705972	0.0113255	0.000000000468649	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0645522	0.0103606	0.000000000477631	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0574142	0.00921856	0.0000000004849564	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0584017	0.00937822	0.0000000004872412	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0832821	0.013374	0.0000000004878879	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0573257	0.00920741	0.0000000004914158	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0513209	0.00824569	0.0000000004979437	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.0513206	0.00824569	0.0000000004980418	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0583415	0.00938212	0.0000000005159399	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0512073	0.00824574	0.0000000005435814	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.051192	0.00824575	0.0000000005500548	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.195833	0.0315486	0.0000000005511802	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0571913	0.00921748	0.0000000005628903	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0511566	0.00824576	0.0000000005652761	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23404110	chr11:68609590	11	68609590	CPT1A	North shore	-0.00373	0.00057	0.00000000057	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg04732324	chr11:68564292	11	68564292	CPT1A	Open sea	-0.08922	0.0144	0.000000000588	-	25650246_gestational_age
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.08497	0.0138	0.000000000644	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0701718	0.0113504	0.0000000006484337	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0517832	0.00837679	0.0000000006507722	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0509404	0.00824585	0.0000000006676028	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0509401	0.00824585	0.0000000006677756	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0509026	0.00824587	0.0000000006872462	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0509011	0.00824587	0.0000000006880197	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0508777	0.00824588	0.0000000007005318	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0508457	0.00824589	0.0000000007178991	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0586217	0.00950822	0.0000000007216408	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0578862	0.00938932	0.0000000007227688	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0507658	0.00824593	0.0000000007632053	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0577604	0.00938321	0.0000000007668679	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.28241	0.0459055	0.0000000007820828	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.165128	0.0268518	0.0000000007937642	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0506947	0.00824596	0.0000000008058836	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0692018	0.0112611	0.0000000008193319	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg10970946	chr11:68540864	11	68540864	CPT1A	Open sea	-0.238425	0.0388055	0.0000000008209006	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0565958	0.009211	0.0000000008236075	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0520289	0.00847197	0.0000000008396609	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0574363	0.00936876	0.0000000008978092	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0563565	0.00919473	0.0000000009057254	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0505399	0.00824602	0.0000000009069121	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.057004	0.00930684	0.0000000009302469	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0630743	0.0102988	0.0000000009332414	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	-0.380332	0.0621269	0.0000000009449102	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-12.5	2	0.00000000096	-	28002404_body_mass_index_all_ancestry_replication
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.378678	0.0619065	0.0000000009744101	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0572891	0.00936536	0.0000000009770029	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19417588	chr11:68529067	11	68529067	CPT1A	Open sea	0.00792	0.00123	0.000000001	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.007034	0.0011515	0.00000000101	-	28213390_serum_triglycerides_discovery_adjusted_for_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0519434	0.00850074	0.000000001018619	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0503157	0.00824611	0.000000001075504	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0503042	0.00824612	0.000000001084969	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15616358	chr11:68610296	11	68610296	CPT1A	North shore	-0.00031	0.000051	0.0000000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.286772	0.0470537	0.000000001120624	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0502506	0.00824614	0.000000001129969	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0692455	0.0113734	0.000000001169285	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_4
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg13786863	chr11:68610743	11	68610743	CPT1A	North shore	0.00919	0.0015	0.00000000117	-	23334450_rheumatoid_arthritis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12031060	chr11:68550320	11	68550320	CPT1A	Island	0.01258	0.00197	0.0000000012	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0501642	0.00824618	0.000000001206426	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0509633	0.00838887	0.000000001269654	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.058482	0.00962928	0.000000001283651	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0500751	0.00824621	0.000000001290448	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0500506	0.00824622	0.000000001314506	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0583984	0.00962547	0.000000001334731	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0500111	0.00824624	0.000000001354304	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0499774	0.00824625	0.000000001389148	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Discovery and replication	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	979	1	48.3	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-16.79	2.75	0.00000000139	-	27777315_postprandial_lipemia_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0558001	0.0092103	0.000000001408083	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0516928	0.00853272	0.000000001410354	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0507254	0.00837563	0.000000001426874	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0507264	0.00837693	0.000000001434102	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.051739	0.00854523	0.000000001440907	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0499233	0.00824628	0.000000001447051	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0508373	0.00840607	0.000000001505151	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0557702	0.0092252	0.000000001526328	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_3
Irvin MR	-	24920721	2014-08-12	Triglycerides	EFO_0004530	Discovery	Table 1	DNA methylation	Triglycerides	Age, sex and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	CD4+ T-cells	Triglycerides levels were log-transformed	991	1	49	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.027	0.00436	0.00000000153	-	24920721_triglycerides
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0014	None	0.0000000016	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0497821	0.00824633	0.000000001609191	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0497784	0.00824634	0.000000001613603	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.231547	0.0384382	0.000000001737459	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0564261	0.00937981	0.000000001833711	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0683653	0.0113743	0.000000001893076	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0495485	0.00824643	0.000000001916981	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0496914	0.00827334	0.000000001944023	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0567278	0.00944887	0.000000001974851	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0494229	0.00824648	0.000000002105557	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.307307	0.0512827	0.000000002106448	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	0.0493689	0.0082465	0.000000002192049	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0501714	0.00838157	0.000000002201867	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0620782	0.0103709	0.000000002203376	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_4
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-	-	0.00000000228	-	28095459_body_mass_index_metaanalysis
Hedman AK	-	28213390	2017-02-17	Serum total cholesterol	EFO_0004574	Discovery adjusted for BMI	Table S6	DNA methylation	Serum total cholesterol	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	2306	2	68	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-9.48e-05	1.59e-05	0.00000000236	-	28213390_serum_total_cholesterol_discovery_adjusted_for_bmi
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10132543	chr11:68609520	11	68609520	CPT1A	North shore	0.00836	0.00133	0.0000000024	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	-0.0492082	0.00824657	0.00000000247048	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0492027	0.00824657	0.000000002480545	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0491825	0.00824658	0.000000002518063	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0597978	0.0100376	0.000000002621921	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0654923	0.0110009	0.000000002687206	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0673281	0.0113129	0.000000002718349	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0490745	0.00824662	0.00000000272817	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	2.9	0.495	0.0000000028	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0490041	0.00824665	0.000000002874239	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0489994	0.00824665	0.000000002884203	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	APOC3 protein levels (SeqId = 6461-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APOC3 protein levels (SeqId = 6461-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Apolipoprotein C-III	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.93	0.156	0.0000000029	None	Gadd-DA_apoc3_protein_levels__seqid___6461-54__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0563016	0.00948723	0.00000000301465	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0598618	0.0100901	0.000000003046133	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13786863	chr11:68610743	11	68610743	CPT1A	North shore	-0.00018	0.000029	0.0000000031	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0488993	0.00824669	0.000000003105692	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg22345647	chr11:68609526	11	68609526	CPT1A	North shore	0.01157	0.002	0.00000000323	-	23334450_rheumatoid_arthritis
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Discovery and replication	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	979	1	48.3	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-43.83	7.34	0.00000000333	-	27777315_postprandial_lipemia_discovery_and_replication
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg01260103	chr11:68609203	11	68609203	CPT1A	Island	0.00558	9e-04	0.00000000347	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0546752	0.00925528	0.000000003551075	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	-0.0487157	0.00824677	0.000000003555647	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0563658	0.00954364	0.000000003580343	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0486963	0.00824678	0.000000003606759	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0486568	0.00824679	0.000000003713001	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0495055	0.00839196	0.000000003734001	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0611608	0.0103777	0.000000003864619	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.048555	0.00824683	0.00000000400114	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0499406	0.00848227	0.00000000400314	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_3
Hedman AK	-	28213390	2017-02-17	Serum total cholesterol	EFO_0004574	Discovery	Table S2	DNA methylation	Serum total cholesterol	Age, sex, white cell counts, and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	Meta-analysis of 2 discovery cohorts	2306	2	68	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-9.34e-05	1.59e-05	0.00000000419	-	28213390_serum_total_cholesterol_discovery
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00027262	4.6e-05	0.0000000042	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	L-LDL-FC_pct	None	Meta-analysis	Table S2	DNA methylation	L-LDL-FC_pct	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	%	Illumina HumanMethylation450	Whole blood	Free cholesterol to total lipids ratio in large LDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.58	0.098	0.0000000043	None	33413638_Gomez-Alonso-MDC_l-ldl-fc_pct_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0569489	0.00970236	0.000000004463143	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	-0.0483957	0.0082469	0.000000004496348	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0550527	0.00938216	0.000000004511266	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0543952	0.0092708	0.000000004523065	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0549955	0.00937377	0.000000004534364	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0540062	0.00920579	0.000000004545659	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0483659	0.00824691	0.000000004595342	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.048362	0.00824691	0.000000004608499	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0607673	0.0103675	0.00000000469035	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0483188	0.00824693	0.000000004756102	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0482403	0.00824696	0.000000005036571	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Cardona A	EPIC-Norfolk	31506343	2019-09-10	Type II diabetes	EFO_0001360	Discovery	Table 2	Type II diabetes	DNA methylation	Age, sex, cell composition (reference based), batch effects	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1264	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.37	None	0.0000000052	None	31506343_Cardona-A_type_ii_diabetes_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0490186	0.00838932	0.000000005236209	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0557643	0.0095486	0.000000005329159	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0489676	0.00838629	0.000000005362336	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	APOC3 protein levels (SeqId = 6461-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APOC3 protein levels (SeqId = 6461-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Apolipoprotein C-III	774	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.77	0.132	0.0000000054	None	Gadd-DA_apoc3_protein_levels__seqid___6461-54__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0481306	0.008247	0.000000005455363	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0556418	0.00954356	0.000000005649258	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0663177	0.0113807	0.000000005754826	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	SCUBE1 protein levels (SeqId = 8989-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SCUBE1 protein levels (SeqId = 8989-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal peptide, CUB and EGF-like domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.91	0.156	0.0000000058	None	Gadd-DA_scube1_protein_levels__seqid___8989-40__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0546125	0.00937524	0.000000005824418	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_2
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00092	None	0.0000000059	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Gadd DA	Generation Scotland	35945220	31/07/2022	APOC3 protein levels (SeqId = 6461-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APOC3 protein levels (SeqId = 6461-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Apolipoprotein C-III	774	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.72	0.124	0.0000000059	None	Gadd-DA_apoc3_protein_levels__seqid___6461-54__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0496867	0.0085353	0.000000005960684	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	-0.0480086	0.00824705	0.000000005961009	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12691334	chr11:68610186	11	68610186	CPT1A	North shore	-0.0012	0.00021	0.0000000061	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg18445292	chr11:68610381	11	68610381	CPT1A	North shore	0.02339	0.004	0.00000000611	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0479596	0.00824707	0.000000006176586	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Replication	Table S5	DNA methylation	Serum triglycerides	Age, sex, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1955	3	61	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0103762	0.0017854	0.00000000618	-	28213390_serum_triglycerides_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0544828	0.00937175	0.000000006244864	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0545375	0.00938765	0.000000006395911	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_2
Richard MA	CHARGE	29198723	2019-11-25	Systolic Blood Pressure	EFO_0006335	Meta-analysis	Table S4	DNA methylation	Systolic Blood Pressure	Age, sex, smoking, batch effects, ancestry, body mass index, blood cell counts	Beta Values	mmHg	Illumina HumanMethylation450	Whole blood, CD4+ T cells	Overall meta-analysis of discovery and replication cohorts	17010	14	Adults	Both	African, Admixed, European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.000057	None	0.0000000067	None	29198723_Richard-MA_systolic_blood_pressure_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0478467	0.00824712	0.00000000670305	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.047812	0.00824713	0.000000006872989	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0477795	0.00824714	0.000000007036394	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0532119	0.00920574	0.000000007608725	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0552435	0.00956482	0.000000007818743	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.063582	0.011011	0.00000000787974	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-12.71	2.2	0.0000000079	-	28002404_body_mass_index_european_ancestry_replication
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg20228509	chr11:68609166	11	68609166	CPT1A	Island	1.983403	0.3437	0.00000000792	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0534808	0.00927757	0.000000008353424	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10970946	chr11:68540864	11	68540864	CPT1A	Open sea	0.00086	None	0.0000000084	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.248156	0.0430632	0.000000008415679	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0574054	0.00996613	0.000000008577676	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0769389	0.0133583	0.000000008597949	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery and replication adjusted for waist circumference	Table 3	DNA methylation	Triglycerides	Age, sex, smoking, waist circumference, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	1485	2	64	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.012	0.0021	0.0000000088	-	28194238_triglycerides_discovery_and_replication_waist_circumference_adjusted
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	-0.273677	0.047593	0.000000009055044	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0544992	0.0094787	0.000000009121332	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0527796	0.00918039	0.000000009146904	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0473885	0.0082473	0.000000009322695	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0481413	0.00838143	0.00000000944069	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_2
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg20201954	chr11:68609518	11	68609518	CPT1A	North shore	0.00729	0.0013	0.0000000095	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0736673	0.0128284	0.000000009512849	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.065465	0.0114001	0.000000009514695	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.00067	0.00012	0.0000000099	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0589957	0.0102877	0.000000009969497	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.253575	0.0442955	0.00000001053821	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24366211	chr11:68610706	11	68610706	CPT1A	North shore	-0.00018	0.000032	0.000000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0471073	0.00824741	0.00000001139703	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Juvinao-Quintero DL	ALSPAC, LBC1936, RSIII-1, RS-Bios	33622391	2021-02-23	Type 2 diabetes	EFO_0001360	meta-analysis	Table 2	DNA methylation	Type 2 diabetes	age, sex, batch effects, cell composition (reference based), smoking	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3428	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.007	0.00125	0.000000012	None	33622391_Juvinao-Quintero-DL_type_2_diabetes_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0469845	0.00824745	0.00000001243885	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0535983	0.00941257	0.00000001262329	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg25464950	chr11:68600521	11	68600521	CPT1A	Open sea	-0.326736	0.0573853	0.00000001263169	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0469518	0.00824747	0.00000001273118	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.353368	0.0620904	0.00000001282153	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg01926073	chr11:68565744	11	68565744	CPT1A	Open sea	0.0027	0.00044	0.000000013	None	33564054_Kashima-K_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0469188	0.00824748	0.00000001303317	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0469075	0.00824748	0.00000001313785	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0525396	0.00924039	0.00000001326364	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0468799	0.00824749	0.00000001339743	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.180366	0.0317589	0.00000001374766	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0541937	0.00955998	0.00000001465088	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0605342	0.0106888	0.00000001512517	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.046675	0.00824757	0.00000001548891	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0531013	0.00938344	0.00000001550703	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0480484	0.00849069	0.00000001551438	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0530072	0.00936717	0.00000001552599	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_2
Irvin MR	-	24920721	2014-08-12	Very low-density lipoprotein cholesterol	EFO_0008317	Discovery	Table 1	DNA methylation	Very low-density lipoprotein cholesterol	Age, sex and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	CD4+ T-cells	Very low-density lipoprotein cholesterol levels were log-transformed	991	1	49	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.019	0.00331	0.0000000157	-	24920721_very_lowdensity_lipoprotein_cholesterol
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.046631	0.00824759	0.00000001597731	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Nano J	-	28624579	2017-06-15	Gamma-glutamyl transferase	EFO_0004532	Meta-analysis	Table S2	DNA methylation	Gamma-glutamyl transferase	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	-	1450	2	63.5	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.006	0.001	0.000000016	-	28624579_gammaglutamyl_transferase_metaanalysis
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg10553894	chr11:68550534	11	68550534	CPT1A	Island	-1.265211	0.224	0.0000000162	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0466045	0.0082476	0.00000001627895	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0524782	0.00928853	0.00000001636329	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0532907	0.00943729	0.000000016647	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0524543	0.00929273	0.00000001685769	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.046536	0.00824763	0.00000001708423	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0465318	0.00824763	0.00000001713488	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.060905	0.0107977	0.00000001726501	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0465117	0.00824764	0.00000001737931	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	0.0005	0.000088	0.000000018	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.05632	0.0100128	0.00000001891017	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Aslibekyan S	-	28139377	2016-11-14	Plasma adiponectin	EFO_0004502	Discovery adjusted for BMI	Table 3	DNA methylation	Plasma adiponectin	Age, sex, body mass index and technical covariates	Beta values	ug/dl	Illumina HumanMethylation450	CD4+ T-cells	Plasma adiponectin levels were log transformed	991	1	49	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.008	0.001	0.000000019	-	28139377_plasma_adiponectin_discovery_adjusted_for_bmi
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	L-VLDL-TG	None	Meta-analysis	Table S2	DNA methylation	L-VLDL-TG	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Triglycerides in large VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-13.2	2.34	0.000000019	None	33413638_Gomez-Alonso-MDC_l-vldl-tg_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14247222	chr11:68549334	11	68549334	CPT1A	North shore	-0.0034	0.00061	0.00000002	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0463092	0.00824771	0.00000002003721	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.053321	0.00949755	0.00000002010863	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.200104	0.0356567	0.00000002031039	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0537832	0.00958517	0.00000002046999	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_3
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg12598007	chr11:68607069	11	68607069	CPT1A	Island	0.00687	0.0012	0.0000000205	-	23334450_rheumatoid_arthritis
Aslibekyan S	-	26110892	2015-07-01	Waist circumference	EFO_0004342	ARIC	Table 3	DNA methylation	Waist circumference	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	cm	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of waist circumference	2106	1	56	Both	African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.004	7e-04	0.000000021	-	26110892_waist_circumference_aric
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	-0.216363	0.0386153	0.00000002138448	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting glucose	EFO_0004465	Base plus BMI	Supplementary Data 1	DNA methylation	fasting glucose	Age, sex, smoking, cell composition (reference based), batch effects, body mass index	Beta Values	mmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-1.89	0.34	0.000000022	4807	31197173_Liu-J_fasting_glucose_base_plus_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.05149	0.00920347	0.00000002250535	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	0.057791	0.0103448	0.00000002358717	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0460247	0.00824782	0.00000002444524	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	0.057285	0.0102692	0.00000002471486	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0530751	0.00951666	0.00000002489288	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.051197	0.00918593	0.00000002541885	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.053718	0.00963859	0.00000002544761	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0524703	0.00941839	0.00000002576674	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0714228	0.0128236	0.0000000259729	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.046684	0.00838363	0.00000002614923	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_2
Li M	None	33279932	2020-12-14	Schizophrenia	EFO_0000692	main	Table 1	DNA methylation	Schizophrenia	age, sex, batch effects	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	999	None	Adults	Both	East Asian	cg14443077	chr11:68606701	11	68606701	CPT1A	Island	0.00878	0.00158	0.000000028	None	33279932_Li-M_schizophrenia_main
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0520795	0.00937393	0.00000002811859	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0473488	0.00852957	0.00000002887389	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07669138	chr11:68583531	11	68583531	CPT1A	Open sea	0.0017	None	0.000000029	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-2.8	0.505	0.000000029	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0457781	0.00824792	0.00000002901899	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0457608	0.00824792	0.0000000293694	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.335751	0.0605383	0.00000002961852	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0467897	0.0084412	0.00000003024401	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0574573	0.0103693	0.00000003058004	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0456905	0.00824795	0.00000003083548	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0519429	0.00937733	0.00000003090827	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0456866	0.00824795	0.00000003091724	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0519088	0.00937341	0.00000003114268	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0509221	0.00919833	0.00000003147512	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0509665	0.00920873	0.00000003173158	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0456413	0.00824797	0.00000003190163	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0455998	0.00824798	0.00000003283015	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.050896	0.00920942	0.00000003322209	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0499223	0.0090386	0.00000003384878	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0463162	0.00838648	0.00000003394667	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12598007	chr11:68607069	11	68607069	CPT1A	Island	0.0021	0.00039	0.000000034	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	-0.0455275	0.00824801	0.0000000345115	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0462265	0.00838339	0.00000003565925	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Discovery	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	653	1	48	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-19.93	3.57	0.0000000358	-	27777315_postprandial_lipemia_discovery
Bozack	PRISM	34569420	Oct 22, 2021	Infant sex	PATO_0001894	Umbilical artery	Supplementary table 10	DNA methylation	Infant sex	Cell composition (reference free), Batch effects, Ancestry (other)	M values	None	Illumina HumanMethylation450	Umbilical artery	None	229	1	Infants	Both	European, African, Other	cg15616358	chr11:68610296	11	68610296	CPT1A	North shore	None	None	0.000000036	None	34569420_Bozack_infant_sex_umbilical_artery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20629021	chr11:68580041	11	68580041	CPT1A	Open sea	-0.267733	0.0485742	0.00000003602009	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0530593	0.00963696	0.00000003736407	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg09972762	chr11:68553421	11	68553421	CPT1A	South shelf	0.11369	0.0207	0.0000000383	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0453703	0.00824807	0.00000003845774	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0528802	0.00961475	0.00000003863537	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0453395	0.00824808	0.00000003928141	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	0.0453275	0.00824809	0.0000000396071	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0530459	0.00965623	0.00000004007515	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0453058	0.00824809	0.00000004020224	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0621295	0.0113203	0.00000004125435	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0625527	0.0114051	0.00000004212382	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_4
Demerath EW	-	25935004	2015-08-01	Body mass index change	EFO_0004340, EFO_0005937	-	Table S3	DNA methylation	Body mass index change	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index change	2096	1	56.2	Both	African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0024	4e-04	0.000000043	-	25935004_body_mass_index_change
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0522492	0.00953287	0.00000004300343	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0505413	0.00922141	0.00000004302446	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0452046	0.00824813	0.00000004309205	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0508467	0.00928418	0.00000004404387	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0567012	0.0103566	0.00000004449407	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0513647	0.00938558	0.00000004504423	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0503106	0.00919491	0.00000004533812	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_2
Hedman AK	-	28213390	2017-02-17	Serum triglycerides	EFO_0004530, CHEBI_17855	Replication adjusted for BMI	Table S9	DNA methylation	Serum triglycerides	Age, sex, body mass index, cell counts and technical covariates	Beta values	mg/dl	Illumina HumanMethylation450	Whole blood	-	1955	3	61	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0102428	0.0018737	0.0000000458	-	28213390_serum_triglycerides_replication_adjusted_for_bmi
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10703936	chr11:68549447	11	68549447	CPT1A	North shore	0.00879	0.00154	0.000000046	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0550676	0.0100733	0.00000004660327	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.065	0.012	0.000000047	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0457983	0.00838598	0.00000004803654	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0515207	0.00943381	0.00000004804094	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.051125	0.00936244	0.00000004821046	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.045511	0.00833481	0.00000004829288	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0456958	0.00838214	0.00000005073454	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03475843	chr11:68529097	11	68529097	CPT1A	Open sea	0.0012	None	0.000000055	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20228509	chr11:68609166	11	68609166	CPT1A	Island	0.00041	None	0.000000055	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0448418	0.00824827	0.00000005520408	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0695146	0.0128027	0.00000005735299	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.049995	0.00921232	0.00000005822837	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0447297	0.00824831	0.00000005956855	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0446911	0.00824832	0.00000006115147	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0446863	0.00824832	0.00000006134754	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0502998	0.00928489	0.0000000614306	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg09972762	chr11:68553421	11	68553421	CPT1A	South shelf	-0.01625	0.003	0.0000000623	-	23334450_rheumatoid_arthritis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19081843	chr11:68606654	11	68606654	CPT1A	North shore	0.0018	None	0.000000064	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	SCUBE1 protein levels (SeqId = 8989-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SCUBE1 protein levels (SeqId = 8989-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal peptide, CUB and EGF-like domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.71	0.132	0.00000007	None	Gadd-DA_scube1_protein_levels__seqid___8989-40__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0458295	0.00849664	0.00000007003619	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.055502	0.0102968	0.00000007145099	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.245767	0.0456215	0.0000000725484	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.252719	0.0469322	0.00000007348366	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0443546	0.00824845	0.00000007675925	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0443512	0.00824845	0.00000007693174	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0506498	0.00942138	0.00000007730244	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0459574	0.00855102	0.00000007797419	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Albao D.	None	31691802	2019-12-15	Type II diabetes mellitus	EFO_0001360	Linear regression	Table 3	DNA methylation	Type II diabetes mellitus	Age, sex	M Values	None	Illumina HumanMethylationEPIC	Whole Blood	None	365	2	Adults	Both	South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	None	None	0.000000082	Type 2 diabetes, p-value	31691802_Albao-D._type_ii_diabetes_mellitus_linear_regression
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0512178	0.00954778	0.0000000824692	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0442305	0.00824849	0.00000008343794	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0553653	0.0103283	0.00000008421991	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0456092	0.00851118	0.00000008506861	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.055753	0.0104066	0.00000008567397	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0515834	0.00962891	0.00000008582873	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0552829	0.0103232	0.00000008674855	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0441639	0.00824852	0.00000008724708	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0713938	0.0133387	0.00000008810833	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0493334	0.00922223	0.00000008957128	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0440922	0.00824854	0.00000009154307	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0440905	0.00824854	0.00000009164759	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0447418	0.00837495	0.00000009312582	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.050324	0.00943241	0.00000009684877	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg09806934	chr11:68608813	11	68608813	CPT1A	Island	0.00677	0.0013	0.0000000971	-	23334450_rheumatoid_arthritis
Kriebel J	-	27019061	2016-03-28	Fasting glucose	EFO_0004465	-	Table 3	Fasting glucose	DNA methylation	Age, sex, smoking, cell counts and technical covariates	SD	Beta values	Illumina HumanMethylation450	Whole blood	Regression coefficients are per 1% increase in DNA methylation	1448	1	59	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.097	0.0182	0.000000098	-	27019061_fasting_glucose
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Discovery	Table 2	DNA methylation	Triglycerides	Age, sex, smoking, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	725	1	60	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0183	0.0034	0.0000000984	-	28194238_triglycerides_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	0.200419	0.0375907	0.00000009850763	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0512012	0.00960245	0.00000009852259	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0607465	0.0113957	0.00000009930253	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0456129	0.00855833	0.00000009986068	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0447266	0.00839366	0.0000001004254	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0439351	0.0082486	0.0000001016738	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Replication	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	326	1	48.8	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-25.87	4.75	0.000000105	-	27777315_postprandial_lipemia_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0553482	0.0104072	0.0000001062918	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0514466	0.00968178	0.000000108958	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25464950	chr11:68600521	11	68600521	CPT1A	Open sea	-0.043821	0.00824864	0.0000001097075	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.067	0.0125	0.00000011	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0453203	0.0085341	0.000000110926	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0489427	0.00921765	0.0000001114255	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0547488	0.0103312	0.0000001178925	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0436846	0.00824869	0.0000001201086	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0436835	0.00824869	0.0000001201987	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0512528	0.0096784	0.0000001203512	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0506935	0.0095805	0.000000123184	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0436448	0.0082487	0.0000001233252	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0219	0.00413	0.000000125	-	28095459_body_mass_index_framingham_heart_study_batch_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01926073	chr11:68565744	11	68565744	CPT1A	Open sea	0.01738	0.00317	0.00000013	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00029065	5.47e-05	0.000000131	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0435329	0.00824874	0.0000001328065	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0489248	0.00927603	0.0000001351412	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0489943	0.00929118	0.0000001359652	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0434804	0.00824876	0.000000137498	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0448398	0.00850949	0.0000001388173	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0434656	0.00824877	0.0000001388502	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03475843	chr11:68529097	11	68529097	CPT1A	Open sea	0.0041	None	0.00000014	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0434372	0.00824878	0.0000001414773	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0434221	0.00824878	0.0000001428904	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0434205	0.00824878	0.0000001430466	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0792415	0.0150575	0.0000001440282	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0433754	0.0082488	0.0000001473637	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0544815	0.0103697	0.0000001510046	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0505521	0.00962725	0.0000001534409	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.138274	0.0263438	0.0000001548696	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0513347	0.00978169	0.00000015587	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0572092	0.0109018	0.0000001561717	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11867574	chr11:68575227	11	68575227	CPT1A	Open sea	0.0045	None	0.00000016	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0486442	0.00928055	0.0000001614673	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.296486	0.0566177	0.0000001653544	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	TotFA	EFO_0005110, EFO_0005110	Meta-analysis	Table S2	DNA methylation	TotFA	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Total fatty acids	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-1.9	0.36	0.00000017	None	33413638_Gomez-Alonso-MDC_totfa_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26192826	chr11:68598649	11	68598649	CPT1A	Open sea	-0.011	0.0021	0.00000017	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0539329	0.0103161	0.0000001737041	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0445241	0.00852573	0.0000001791093	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.043073	0.00824891	0.0000001797475	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	M-VLDL-TG	None	Meta-analysis	Table S2	DNA methylation	M-VLDL-TG	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Triglycerides in medium VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-7.1	1.37	0.00000018	None	33413638_Gomez-Alonso-MDC_m-vldl-tg_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20629021	chr11:68580041	11	68580041	CPT1A	Open sea	-0.0007	0.00013	0.00000018	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0445966	0.00854462	0.0000001820875	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0484029	0.00927837	0.0000001845739	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0430286	0.00824892	0.0000001850465	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.0430242	0.00824893	0.000000185584	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0429534	0.00824895	0.000000194374	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0429228	0.00824896	0.0000001982901	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0429191	0.00824896	0.0000001987707	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0495727	0.00953792	0.0000002047768	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	-0.0428601	0.00824898	0.0000002065654	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0428539	0.00824899	0.0000002074032	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21868480	chr11:68547532	11	68547532	CPT1A	North shelf	0.0036	None	0.00000021	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0660852	0.0127276	0.0000002105398	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.047794	0.00921208	0.000000215188	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0486472	0.0093793	0.0000002169592	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0539552	0.0104072	0.0000002195814	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0491876	0.00948824	0.0000002199972	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_4
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	None	None	0.00000022	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	0.0427564	0.00824902	0.00000022099	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0427446	0.00824903	0.000000222691	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0520607	0.0100475	0.0000002230623	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0438681	0.00847009	0.0000002258163	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.068556	0.0132378	0.0000002262722	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0426799	0.00824905	0.0000002322497	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0426714	0.00824905	0.0000002335382	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0588534	0.0113785	0.0000002342373	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	-0.201662	0.0390088	0.000000237017	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0483389	0.00935973	0.0000002441607	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0425869	0.00824908	0.0000002467032	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11220908	chr11:68541142	11	68541142	CPT1A	Open sea	0.0035	None	0.00000025	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0586804	0.0113767	0.0000002529509	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	-0.0495792	0.00961968	0.0000002583883	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0425058	0.00824911	0.0000002599961	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.0425031	0.00824911	0.0000002604524	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.206165	0.0400178	0.0000002608077	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.042493	0.00824911	0.0000002621527	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0536318	0.0104129	0.0000002631425	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0431476	0.00839154	0.0000002756318	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13227195	chr11:68571630	11	68571630	CPT1A	Open sea	-0.0424085	0.00824914	0.0000002768517	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0494287	0.00962449	0.0000002846693	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0494813	0.0096363	0.0000002859299	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.0423559	0.00824916	0.0000002864096	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0476051	0.00928276	0.0000002960339	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0476931	0.00930919	0.0000003041625	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0422442	0.0082492	0.0000003077535	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous decade consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	None	None	0.00000031	None	31789449_Dugue-P-A_alcohol_consumption_previous_decade_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0493422	0.00964104	0.0000003128181	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0422134	0.00824921	0.0000003139152	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0517787	0.0101235	0.0000003182335	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06042565	chr11:68564477	11	68564477	CPT1A	Open sea	0.0014	None	0.00000032	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-13.56	2.65	0.00000032	-	28002404_body_mass_index_european_ancestry_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0421796	0.00824922	0.000000320799	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0421658	0.00824923	0.0000003236533	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0477705	0.00935866	0.0000003359605	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0436774	0.00856026	0.0000003396688	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21868480	chr11:68547532	11	68547532	CPT1A	North shelf	0.001	None	0.00000034	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0436252	0.00855102	0.0000003407314	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	-0.241093	0.0472961	0.0000003477646	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.268776	0.0527868	0.0000003585435	None	39706196_Hannah-M.-Smith_body_fat_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20228509	chr11:68609166	11	68609166	CPT1A	Island	-0.00029	0.000058	0.00000036	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0466936	0.00917765	0.0000003668179	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0670022	0.0131705	0.0000003677071	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0419191	0.00824931	0.0000003790177	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0577258	0.0113684	0.0000003866349	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0469729	0.00925278	0.0000003889029	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0649455	0.0127967	0.0000003918844	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0670502	0.0132125	0.0000003927665	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.0441736	0.00871517	0.0000004056639	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0558838	0.0110281	0.0000004081928	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.0417542	0.00824937	0.0000004210148	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0467972	0.00924956	0.0000004256763	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0417341	0.00824938	0.0000004264068	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	0.0492391	0.00973544	0.0000004294246	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0417101	0.00824939	0.0000004329829	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.235419	0.0465913	0.000000439667	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0416831	0.0082494	0.0000004404699	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0476518	0.00943198	0.0000004421224	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	-0.049121	0.00972334	0.00000044278	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0485827	0.00961946	0.0000004460328	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0473185	0.00937059	0.0000004478522	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0416542	0.00824941	0.0000004486267	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.047623	0.00943625	0.0000004546131	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0416261	0.00824942	0.0000004566673	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0467716	0.00927064	0.0000004586399	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0423202	0.00839486	0.000000468144	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0415824	0.00824943	0.0000004695174	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0422636	0.00838521	0.0000004704489	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0415736	0.00824943	0.0000004721326	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0490477	0.00974114	0.0000004832534	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0415059	0.00824946	0.0000004927843	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	0.0414989	0.00824946	0.0000004950006	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0414782	0.00824947	0.0000005014893	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.067009	0.0133383	0.0000005125236	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0414086	0.00824949	0.0000005240319	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0471358	0.00941813	0.0000005657152	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0545707	0.0109089	0.0000005727077	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0482043	0.00963849	0.0000005762479	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0639282	0.0127827	0.0000005764972	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0463096	0.00926494	0.0000005848495	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0503395	0.0100719	0.0000005859306	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.214314	0.0429358	0.0000006046075	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.0411701	0.00824957	0.0000006089019	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0480558	0.00962956	0.0000006093048	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0568641	0.0113962	0.0000006115192	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0411567	0.00824958	0.0000006140437	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0750649	0.0150702	0.0000006396732	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PSAT1 protein levels (SeqId = 18342-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSAT1 protein levels (SeqId = 18342-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphoserine aminotransferase	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.78	0.156	0.00000067	None	Gadd-DA_psat1_protein_levels__seqid___18342-2__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0027	None	0.00000067	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0477974	0.00961962	0.0000006814754	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0493384	0.00993398	0.0000006889528	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.040966	0.00824964	0.0000006918925	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.231541	0.0466346	0.0000006932086	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0409516	0.00824965	0.0000006981548	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05710301	chr11:68540704	11	68540704	CPT1A	Open sea	-0.14703	0.0297101	0.0000007533416	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0561633	0.0113516	0.0000007596151	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0407923	0.0082497	0.0000007710226	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0407877	0.0082497	0.0000007732603	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0462319	0.00935166	0.0000007749644	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.0431194	0.0087297	0.0000007923062	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0509263	0.0103223	0.0000008160931	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.042178	0.00855217	0.0000008234998	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0406779	0.00824974	0.0000008278404	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0561946	0.0113969	0.0000008284282	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0525939	0.0106811	0.0000008571781	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0406006	0.00824976	0.0000008684947	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0556504	0.0113117	0.0000008761868	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.12	0.0248	0.00000089	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0494442	0.0100599	0.0000008975361	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.125214	0.0254943	0.0000009118497	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0627664	0.0127808	0.0000009159747	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.221379	0.0451093	0.0000009298213	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Sikdar S	PACE	31536415	2019-09-19	Prenatal smoke exposure	EFO_0009115, EFO_0008361, EFO_0006527, EFO_0004318	Inverse varience-weighted fixed-effects meta-analysis	Table S1	DNA methylation	Prenatal smoke exposure	Maternal age, socioeconomic position, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Cord blood, whole blood	None	5648	9	Infants	Both	European, African, Unclear	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0028	0.0006	0.00000094	None	31536415_Sikdar-S_prenatal_smoke_exposure_inverse_varience-weighted_fixed-effects_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0739539	0.0150771	0.0000009440764	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg13227195	chr11:68571630	11	68571630	CPT1A	Open sea	0.226382	0.0461581	0.0000009452198	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.0404431	0.00824982	0.0000009573065	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0472233	0.00963299	0.0000009575995	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0500135	0.0102054	0.0000009651809	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	0.040407	0.00824983	0.0000009788746	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0403454	0.00824985	0.000001016742	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0468174	0.00957382	0.000001018296	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.051915	0.0106222	0.000001032473	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25610526	chr11:68569289	11	68569289	CPT1A	Open sea	-0.0402919	0.00824987	0.000001050801	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Cardona A	LOLIPOP	31506343	2019-09-10	Type II diabetes	EFO_0001360	Replication in Indians	Table 3	Type II diabetes	DNA methylation	Cell composition (reference based), batch effects	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	2664	1	Adults	Both	South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.223	None	0.0000011	None	31506343_Cardona-A_type_ii_diabetes_replication_in_indians
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	L-VLDL-P	None	Meta-analysis	Table S2	DNA methylation	L-VLDL-P	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mol/L	Illumina HumanMethylation450	Whole blood	Concentration of large VLDL particles	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-12.3	2.54	0.0000012	None	33413638_Gomez-Alonso-MDC_l-vldl-p_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	WNT5A protein levels (SeqId = 13268-45)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WNT5A protein levels (SeqId = 13268-45)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein Wnt-5a	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.76	0.156	0.0000012	None	Gadd-DA_wnt5a_protein_levels__seqid___13268-45__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10098373	chr11:68550390	11	68550390	CPT1A	Island	0.0024	None	0.0000012	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0463686	0.0095463	0.000001202695	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0464838	0.00957336	0.000001213006	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0467098	0.00962002	0.000001213356	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0400553	0.00824995	0.000001214947	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0451027	0.00929477	0.000001231773	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0505809	0.0104249	0.000001235307	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0400164	0.00824996	0.000001244197	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0450725	0.00929269	0.000001245293	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0455174	0.00939105	0.000001266961	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.0399626	0.00824998	0.000001285743	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Battram T	GEO	27886173	2020-09-15	Inflammatory bowel disease	EFO_0003767	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Inflammatory bowel disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	240	1	Adults	Both	European	cg10098373	chr11:68550390	11	68550390	CPT1A	Island	-0.0689	0.01383	0.0000013	None	27886173_Battram-T_inflammatory_bowel_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Li M	None	33279932	2020-12-14	Schizophrenia	EFO_0000692	adjusted for cell composition	Table 1	DNA methylation	Schizophrenia	age, sex, batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	999	None	Adults	Both	East Asian	cg14443077	chr11:68606701	11	68606701	CPT1A	Island	None	None	0.0000013	None	33279932_Li-M_schizophrenia_adjusted_for_cell_composition
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25610526	chr11:68569289	11	68569289	CPT1A	Open sea	-0.00051	0.0001	0.0000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25610526	chr11:68569289	11	68569289	CPT1A	Open sea	0.00069	None	0.0000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0399403	0.00824998	0.000001303309	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0399772	0.0082597	0.000001311412	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0412248	0.00851872	0.000001316127	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0454136	0.00938856	0.000001330691	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13227195	chr11:68571630	11	68571630	CPT1A	Open sea	-0.0399046	0.00825	0.000001331989	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.054658	0.0113101	0.000001360627	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0460383	0.00952701	0.00000136263	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0517477	0.0107093	0.0000013651	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0445361	0.00921918	0.000001373557	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0500086	0.0103525	0.000001375109	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0398511	0.00825001	0.000001376129	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	0.0398311	0.00825002	0.000001393003	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0464841	0.00963105	0.000001403663	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0398046	0.00825003	0.000001415638	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Sharp GC	-	25855720	2015-08-01	Maternal underweight	EFO_0005936	Birth	Additional file 1	DNA methylation	Maternal underweight	Offspring sex, maternal age, maternal smoking, maternal occupation, parity and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	601	1	0	Both	European	cg20201954	chr11:68609518	11	68609518	CPT1A	North shore	0.02003	0.00416	0.00000144	-	25855720_maternal_underweight_birth
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0440948	0.00914706	0.000001445244	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	-0.0397318	0.00825005	0.000001479633	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0494322	0.0102656	0.000001484155	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0517259	0.0107424	0.000001485819	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0453832	0.00942822	0.000001497571	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0463609	0.00963308	0.000001504001	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0468188	0.00973001	0.000001510717	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-7e-04	0.00015	0.00000152	-	27826092_body_mass_index
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0723607	0.0150594	0.000001562796	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.224385	0.0467012	0.000001562815	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0459716	0.00957143	0.000001578502	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0461264	0.00960478	0.000001582943	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0396006	0.00825009	0.0000016022	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0509423	0.0106184	0.000001621937	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0496625	0.0103576	0.000001644424	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg25464950	chr11:68600521	11	68600521	CPT1A	Open sea	-0.274115	0.0571924	0.000001657928	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	1.6	0.333	0.0000017	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Braun KVE	-	28194238	2016-06-16	Triglycerides	EFO_0004530, CHEBI_17855	Replication	Table 2	DNA methylation	Triglycerides	Age, sex, smoking, cell counts and technical covariates	Beta values	mmol/l	Illumina HumanMethylation450	Whole blood	-	760	1	68	Both	None	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0118	0.0025	0.00000171	-	28194238_triglycerides_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0394784	0.00825013	0.000001725007	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0458286	0.00958186	0.000001745135	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0631435	0.0132053	0.000001755391	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P23142	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P23142	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0394245	0.00825015	0.000001781917	P23142	41361833_Josephine_Robertson_P23142_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0393907	0.00825016	0.000001818574	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Replication	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	326	1	48.8	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-61.31	12.61	0.00000183	-	27777315_postprandial_lipemia_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0396554	0.00831237	0.000001853973	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	0.0393504	0.00825018	0.000001863319	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0447177	0.00937856	0.000001877751	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_2
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	L-VLDL-PL	None	Meta-analysis	Table S2	DNA methylation	L-VLDL-PL	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Phospholipids in large VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-12.2	2.56	0.0000019	None	33413638_Gomez-Alonso-MDC_l-vldl-pl_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.044748	0.00939513	0.000001926644	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0521201	0.0109472	0.000001944515	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0392671	0.0082502	0.000001958994	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0439392	0.0092399	0.000001999686	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_4
Fernández-Sanlés A.	REGICOR, Framingham Offspring Cohort	29326313	2018-01-11	Cardiovascular risk	EFO_0003919, EFO_0004298	Age-independent cardiovascular risk was determined via the residuals approach, results meta-analysesd across discovery and replicaton cohorts	Table 2	DNA methylation	Cardiovascular risk	Sex, age, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole Blood	None	2746	2	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-5	1.05	0.000002	None	29326313_Fernández-Sanlés-A._cardiovascular_risk_age-independent_cardiovascular_risk_was_determined_via_the_residuals_approach__results_meta-analysesd_across_discovery_and_replicaton_cohorts
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15211864	chr11:68531232	11	68531232	CPT1A	Open sea	-0.16256	0.0342075	0.000002027704	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0446454	0.00940677	0.00000209344	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12598007	chr11:68607069	11	68607069	CPT1A	Island	0.00517	0.00106	0.0000021	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg15211864	chr11:68531232	11	68531232	CPT1A	Open sea	2	0.417	0.0000021	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0451426	0.00952345	0.000002155685	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.150022	0.0316524	0.000002157555	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0391183	0.00825608	0.00000217729	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.063434	0.0133927	0.000002195087	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	MUFA	EFO_0006823	Meta-analysis	Table S2	DNA methylation	MUFA	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Monounsaturated fatty acids 16:1, 18:1	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-2.86	0.6	0.0000022	None	33413638_Gomez-Alonso-MDC_mufa_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10098373	chr11:68550390	11	68550390	CPT1A	Island	-0.0012	0.00025	0.0000022	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0455966	0.00962815	0.000002202767	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0390202	0.00825028	0.000002270972	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.044576	0.0094258	0.000002275588	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0451816	0.00955386	0.000002275694	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0401961	0.00850315	0.000002297575	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0389911	0.00825029	0.000002310793	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	-0.0456442	0.00967032	0.000002379877	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Isoleucine	EFO_0009793	None	None	DNA methylation	Isoleucine	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	679	1	Adults	Females	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-15.7	3.3	0.0000024	None	Battram-T_isoleucine
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0536665	0.0113822	0.000002439976	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0394755	0.00837343	0.000002446771	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0388671	0.00825033	0.000002488025	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0483634	0.0102709	0.000002514963	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0474647	0.0100862	0.000002550257	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0388071	0.00825035	0.000002578255	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0389652	0.00829045	0.00000262513	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0436659	0.0092948	0.000002652565	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0433156	0.00922468	0.000002682053	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0400657	0.0085342	0.000002693927	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	0.0482544	0.0102917	0.000002774572	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01009	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01009	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0386716	0.0082504	0.000002794009	P01009	41361833_Josephine_Robertson_P01009_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0515893	0.011013	0.000002832791	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0386379	0.00825041	0.000002850372	A0A075B6I0	41361833_Josephine_Robertson_A0A075B6I0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0386315	0.00825041	0.000002861126	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0386138	0.00825041	0.00000289119	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.119761	0.0255905	0.000002892025	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0386044	0.00825042	0.000002907361	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0498392	0.0106612	0.000002968577	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08850249	chr11:68579907	11	68579907	CPT1A	Open sea	0.269764	0.0577123	0.000002971837	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0385479	0.00825043	0.000003006062	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.03849	0.00825045	0.000003110503	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0384767	0.00825046	0.000003134839	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0483403	0.0103658	0.000003137046	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_4
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg21143706	chr11:68541303	11	68541303	CPT1A	Open sea	-1.24376	0.267	0.00000319	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0384336	0.00825047	0.000003215506	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0384326	0.00825047	0.000003217439	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0689225	0.0148011	0.000003243271	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0485106	0.0104264	0.000003305049	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0383419	0.0082505	0.000003393609	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0595343	0.0128116	0.000003398671	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15748291	chr11:68567642	11	68567642	CPT1A	Open sea	0.258174	0.0556014	0.000003454189	None	39706196_Hannah-M.-Smith_bmi_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26192826	chr11:68598649	11	68598649	CPT1A	Open sea	0.0159	0.00333	0.0000035	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0382891	0.00825052	0.00000350049	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg12598007	chr11:68607069	11	68607069	CPT1A	Island	0.144027	0.0310854	0.000003624386	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0430115	0.00929812	0.000003763037	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0695608	0.015046	0.000003810731	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	-0.219096	0.0474361	0.000003888441	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0381085	0.00825057	0.000003890721	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	L-VLDL-L	None	Meta-analysis	Table S2	DNA methylation	L-VLDL-L	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Total lipids in large VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-12.3	2.67	0.0000039	None	33413638_Gomez-Alonso-MDC_l-vldl-l_meta-analysis
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.048	0.0104	0.0000039	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0380819	0.00825058	0.000003951584	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0380527	0.00825059	0.00000401945	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20629021	chr11:68580041	11	68580041	CPT1A	Open sea	-0.225483	0.048902	0.000004037836	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0380411	0.0082506	0.000004046923	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0425122	0.00922754	0.000004117497	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0380091	0.00825061	0.000004122925	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0439845	0.0095486	0.000004131826	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0380028	0.00825061	0.000004138246	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0379946	0.00825061	0.000004157922	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.037972	0.00825062	0.000004212994	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0385747	0.00838224	0.000004220556	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0476213	0.0103483	0.000004222434	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.037965	0.00825062	0.000004230318	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.037952	0.00825062	0.000004262375	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09806934	chr11:68608813	11	68608813	CPT1A	Island	0.0015	0.00033	0.0000043	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0392461	0.00853657	0.000004313419	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.203771	0.0443449	0.000004355153	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0378501	0.00825066	0.000004522508	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0430417	0.00938893	0.000004592607	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	DEFB1 protein levels (SeqId = 6629-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DEFB1 protein levels (SeqId = 6629-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-defensin 1	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.716	0.156	0.0000046	None	Gadd-DA_defb1_protein_levels__seqid___6629-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0438306	0.00956244	0.000004607641	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0378144	0.00825067	0.000004616976	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0378084	0.00825067	0.000004633196	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25610526	chr11:68569289	11	68569289	CPT1A	Open sea	-0.0378064	0.00825067	0.000004638531	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02146941	chr11:68522449	11	68522449	CPT1A	South shelf	0.146851	0.0320623	0.000004678047	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Sayols-Baixeras S	-	28173150	2016-09-15	Serum triglycerides	EFO_0004530, CHEBI_17855	Discovery adjusted for surrogate variables	Table S1	Serum triglycerides	DNA methylation	Age, sex, smoking, cell counts and technical covariates	mg/dl	M values	Illumina HumanMethylation450	Whole blood	Triglycerides levels were log-transformed	645	1	63.2	Both	None	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.05	0.011	0.0000047	-	28173150_serum_triglycerides_discovery_adjusted_for_surrogate_variables
Gadd DA	Generation Scotland	35945220	31/07/2022	ACY1 protein levels (SeqId = 3343-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACY1 protein levels (SeqId = 3343-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aminoacylase-1	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.72	0.156	0.0000047	None	Gadd-DA_acy1_protein_levels__seqid___3343-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0499586	0.0109129	0.000004734352	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19596755	chr11:68609747	11	68609747	CPT1A	North shore	0.004	0.00087	0.0000048	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0432165	0.00944939	0.000004836515	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.240657	0.0526328	0.000004855563	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0429197	0.00938709	0.000004865673	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0377194	0.0082507	0.000004878161	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_1
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg03404305	chr11:68543216	11	68543216	CPT1A	Open sea	-0.1270008	0.0278161	0.000004978	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0376839	0.00825071	0.000004979495	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0376746	0.00825071	0.000005006252	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0376096	0.00825073	0.000005197615	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0376074	0.00825073	0.000005204371	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg14411524	chr11:68583057	11	68583057	CPT1A	Open sea	-0.221536	0.0486386	0.000005279192	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0468402	0.0102836	0.000005284294	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0459124	0.0100862	0.000005356184	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0375463	0.00825075	0.000005391006	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0381951	0.00839385	0.000005398144	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0472599	0.0103888	0.000005430096	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0420881	0.00925763	0.000005503056	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0388388	0.00854462	0.000005526559	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.042312	0.00931232	0.000005572817	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_3
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg10132543	chr11:68609520	11	68609520	CPT1A	North shore	-1.077158	0.2372	0.00000559	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0439204	0.00966842	0.00000559915	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.21147	0.0465616	0.000005617311	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0427856	0.00942591	0.000005692993	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0374497	0.00825078	0.000005699149	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0044	0.00097	0.0000058	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	0.0374133	0.00825079	0.000005819448	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	-0.0374091	0.00825079	0.000005833378	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.00072386	0.00015892	0.00000585	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.201874	0.0445985	0.000006037728	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0385109	0.00851192	0.000006105565	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	0.0372841	0.00825083	0.000006266987	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0372836	0.00825083	0.000006268603	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0574649	0.0127171	0.000006270497	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg06681290	chr11:68572141	11	68572141	CPT1A	Open sea	-0.189432	0.0419319	0.000006293297	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0434975	0.0096331	0.000006368498	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0416424	0.00922297	0.00000637863	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0469833	0.0104089	0.000006417703	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.044614	0.00988693	0.000006459072	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0456636	0.0101223	0.000006496013	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0455042	0.0100896	0.000006532285	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0493787	0.0109495	0.000006542951	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	ALDOB protein levels (SeqId = 18185-118)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALDOB protein levels (SeqId = 18185-118)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fructose-bisphosphate aldolase B	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.7	0.156	0.0000066	None	Gadd-DA_aldob_protein_levels__seqid___18185-118__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0464113	0.0103009	0.00000667082	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0459807	0.0102118	0.000006761905	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0371086	0.00825088	0.000006927456	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0678631	0.0150926	0.000006962943	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0370984	0.00825089	0.000006968018	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	-0.0370538	0.0082509	0.00000714717	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0370429	0.0082509	0.000007191602	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0683613	0.0152274	0.000007198384	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_4
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	ARIC	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2106	1	56	Both	African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.003	7e-04	0.0000072	-	26110892_body_mass_index_aric
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0375856	0.00838345	0.000007405075	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0374323	0.00835228	0.000007461712	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.036974	0.00825093	0.000007478682	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_1
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg19596755	chr11:68609747	11	68609747	CPT1A	North shore	-0.1587895	0.0354706	0.000007582	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0419476	0.00937546	0.000007727711	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0382122	0.00854342	0.000007781645	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_3
Pfeiffer L	-	25583993	2015-01-12	Triglycerides	EFO_0004530, CHEBI_17855	Replication	Table 2	Triglycerides	DNA methylation	Age, sex, smoking, body mass index, alcohol consumption, physical activity, hypertension, history of MI, hemoglobin A1c, C-reactive protein, lipid-lowering drugs intake and cell counts	mg/dl	Beta values	Illumina HumanMethylation450	Whole blood	-	971	2	62	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	0.00000788	-	25583993_triglycerides_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	-0.0436219	0.00975885	0.000007881309	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.03688	0.00825095	0.000007888677	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	D6RF35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	D6RF35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0375181	0.00839904	0.000007993669	D6RF35	41361833_Josephine_Robertson_D6RF35_OSCA_model_2
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	S-VLDL-TG	None	Meta-analysis	Table S2	DNA methylation	S-VLDL-TG	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Triglycerides in small VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-5.6	1.25	0.000008	None	33413638_Gomez-Alonso-MDC_s-vldl-tg_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0509088	0.0113977	0.000008008085	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0368455	0.00825097	0.000008044276	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0586692	0.0131472	0.000008162077	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0430011	0.00964629	0.000008342373	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	-0.277742	0.0623342	0.00000841493	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.036753	0.00825099	0.00000847596	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0410558	0.00921936	0.000008521672	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.0373276	0.00838641	0.00000861157	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.049554	0.0111341	0.000008624192	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0405259	0.00910628	0.000008637499	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0416201	0.00935502	0.000008692461	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_3
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting glucose	EFO_0004465	Base	Supplementary Data 1	DNA methylation	fasting glucose	Age, sex, smoking, cell composition (reference based), batch effects	Beta Values	mmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-1.1	0.25	0.0000087	4808	31197173_Liu-J_fasting_glucose_base
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	-2.1	0.467	0.0000088	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0366823	0.00825101	0.000008821026	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0467426	0.0105221	0.000008965187	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P23142	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P23142	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0372778	0.00839269	0.000008990546	P23142	41361833_Josephine_Robertson_P23142_OSCA_model_2
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	S-VLDL-CE_pct	None	Meta-analysis	Table S2	DNA methylation	S-VLDL-CE_pct	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	%	Illumina HumanMethylation450	Whole blood	Cholesterol esters to total lipids ratio in small VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	2.02	0.455	0.000009	None	33413638_Gomez-Alonso-MDC_s-vldl-ce_pct_meta-analysis
Nicolas Fragoso-Bargas	EPIPREG	36534481	Dec 19, 2022	HOMA-IR	EFO:0000001	discovery	Supplementary Table 2	DNA methylation	HOMA-IR	Smoking,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	analysis in pregnancy (cross ancestry)	456	1	Adults (18-65 years)	Females	European,South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.122234925	0.027229568	0.00000912	None	36534481_Nicolas-Fragoso-Bargas_homa-ir_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.0366168	0.00825103	0.000009152709	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	0.0430219	0.00970155	0.0000092941	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.0388526	0.00876521	0.000009378375	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	-0.0365622	0.00825105	0.000009438172	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.060719	0.0137046	0.000009466795	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0593042	0.013395	0.000009609133	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	XS-VLDL-TG	None	Meta-analysis	Table S2	DNA methylation	XS-VLDL-TG	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Triglycerides in very small VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-4	0.9	0.0000097	None	33413638_Gomez-Alonso-MDC_xs-vldl-tg_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0365099	0.00825107	0.000009719852	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0502036	0.011347	0.000009741702	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0531138	0.0120072	0.000009781732	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.041688	0.00942898	0.000009883001	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_3
Jiantao Ma	RS, MESA, CARDIA	30796027	Feb 22, 2019	hepatic fat	EFO_0010821	Replication	Table 1	DNA methylation	hepatic fat	Age, Sex, Cell composition (reference based), Batch effects	Beta values	None	Illumina HumanMethylation450	whole blood	None	1904	3	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	None	None	0.0000099	None	30796027_Jiantao-Ma_hepatic_fat_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0364694	0.00825108	0.000009942758	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0461919	0.0104543	0.00001001117	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0459198	0.0104108	0.00001037389	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0363767	0.00825111	0.00001047319	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0422717	0.00958903	0.00001049061	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03855388	chr11:68580018	11	68580018	CPT1A	Open sea	-0.0363587	0.00825111	0.00001057899	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0406053	0.00921751	0.0000106418	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0363348	0.00825112	0.00001072144	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.041259	0.00937419	0.00001083442	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	S-VLDL-PL	None	Meta-analysis	Table S2	DNA methylation	S-VLDL-PL	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Phospholipids in small VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-3.6	0.83	0.000011	None	33413638_Gomez-Alonso-MDC_s-vldl-pl_meta-analysis
Battram T	ARIES	None	2020-08-20	Conjugated linoleic acid	EFO_0006807	None	None	DNA methylation	Conjugated linoleic acid	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	666	1	Adults	Females	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-10.2	2.3	0.000011	None	Battram-T_conjugated_linoleic_acid
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19417588	chr11:68529067	11	68529067	CPT1A	Open sea	-0.0059	0.0013	0.000011	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21143706	chr11:68541303	11	68541303	CPT1A	Open sea	-0.0004	0.000091	0.000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26192826	chr11:68598649	11	68598649	CPT1A	Open sea	0.014	0.0033	0.000011	None	33450751_Mulder-RH_sex_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	-0.191896	0.043658	0.00001112031	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	0.187698	0.042708	0.00001114417	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0419507	0.00955503	0.00001139218	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.0368808	0.0084013	0.00001142018	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.0368981	0.00840596	0.0000114398	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0368006	0.00838418	0.00001145189	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0361934	0.00825116	0.00001160099	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0361724	0.00825117	0.00001173802	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0427709	0.00975899	0.0000118024	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0361515	0.00825117	0.00001187481	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	FHS 2	Table 2	DNA methylation	Body mass index	Age, sex and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	442	1	71	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.04	0.01	0.000012	-	26110892_body_mass_index_fhs_2
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.00202	0.00046	0.000012	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	APOC3 protein levels (SeqId = 6461-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APOC3 protein levels (SeqId = 6461-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Apolipoprotein C-III	774	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.61	0.139	0.000012	None	Gadd-DA_apoc3_protein_levels__seqid___6461-54__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0360985	0.00825119	0.00001223044	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.21944	0.050165	0.00001225011	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0407047	0.00930826	0.00001234136	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0403866	0.009239	0.00001243517	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19596755	chr11:68609747	11	68609747	CPT1A	North shore	-0.108172	0.0247526	0.00001248909	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15211864	chr11:68531232	11	68531232	CPT1A	Open sea	-0.0374786	0.00857922	0.00001259437	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0365143	0.00836166	0.00001269032	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Cholesterol esters in very large VLDL	EFO_0008589	None	None	DNA methylation	Cholesterol esters in very large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	635	1	Adults	Females	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	25	5.7	0.000013	None	Battram-T_cholesterol_esters_in_very_large_vldl
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14443077	chr11:68606701	11	68606701	CPT1A	Island	-0.00036	0.000083	0.000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19081843	chr11:68606654	11	68606654	CPT1A	North shore	0.0058	None	0.000013	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg25610526	chr11:68569289	11	68569289	CPT1A	Open sea	-0.00848	0.0019	0.000013	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.0368646	0.00846138	0.00001328696	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0408579	0.00938182	0.00001339643	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0454773	0.0104573	0.00001377839	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_4
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 1	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	442	1	67	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0429	0.00956	0.000014	-	28095459_body_mass_index_framingham_heart_study_batch_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	None	None	0.000014	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0361972	0.00833465	0.00001415091	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0410691	0.00945852	0.00001421278	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.0376484	0.00867317	0.00001429227	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0358131	0.00825127	0.0000143231	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0409483	0.0094452	0.00001464918	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.039282	0.00906525	0.00001479025	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0493549	0.0113948	0.00001491907	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_4
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	VLDL-TG	None	Meta-analysis	Table S2	DNA methylation	VLDL-TG	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Triglycerides in VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-6.7	1.55	0.000015	None	33413638_Gomez-Alonso-MDC_vldl-tg_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18445292	chr11:68610381	11	68610381	CPT1A	North shore	-0.0066	0.0015	0.000015	None	33450751_Mulder-RH_sex_discovery
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg26192826	chr11:68598649	11	68598649	CPT1A	Open sea	0.0205	0.00456	0.000015	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26906629	chr11:68564367	11	68564367	CPT1A	Open sea	0.0018	None	0.000015	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.035711	0.00825131	0.00001515171	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg25464950	chr11:68600521	11	68600521	CPT1A	Open sea	0.241287	0.0557977	0.00001538218	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0356825	0.00825131	0.00001539101	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0398358	0.0092118	0.00001539373	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0651672	0.0150748	0.00001549959	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_2
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg19596755	chr11:68609747	11	68609747	CPT1A	North shore	-0.00030262	6.97e-05	0.0000157	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0435581	0.0100861	0.00001580319	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	-0.0546704	0.012663	0.0000158962	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-2.5	0.59	0.000016	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0415243	0.00962911	0.00001625722	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0415262	0.00963566	0.00001645875	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_2
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg12691334	chr11:68610186	11	68610186	CPT1A	North shore	0.898195	0.2085	0.0000165	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0444289	0.0103167	0.00001669358	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0637378	0.0148094	0.00001689188	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0470267	0.010928	0.00001693482	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0397257	0.00923202	0.00001695634	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0423288	0.00983702	0.0000169582	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0355024	0.00825137	0.0000169889	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0354671	0.00825138	0.0000173202	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02100918	chr11:68550982	11	68550982	CPT1A	South shore	0.169102	0.0393746	0.00001758753	None	39706196_Hannah-M.-Smith_bmi_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19596755	chr11:68609747	11	68609747	CPT1A	North shore	-0.106022	0.0246965	0.0000177246	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0354209	0.00825139	0.00001776335	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.044779	0.0104332	0.00001782356	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0418559	0.00975338	0.00001786684	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15211864	chr11:68531232	11	68531232	CPT1A	Open sea	-0.0353978	0.0082514	0.00001798807	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.069	0.01603	0.000018	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.0353843	0.0082514	0.00001812104	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0403284	0.0094117	0.00001839646	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0353551	0.00825141	0.00001841239	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0418288	0.00977001	0.00001869456	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0403838	0.00943583	0.00001882188	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0411038	0.00960474	0.00001884781	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0926837	0.0216625	0.00001893291	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.039424	0.00921521	0.00001896506	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_3
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	S-VLDL-C_pct	None	Meta-analysis	Table S2	DNA methylation	S-VLDL-C_pct	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	%	Illumina HumanMethylation450	Whole blood	Total cholesterol to total lipids ratio in small VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	1.33	0.311	0.000019	None	33413638_Gomez-Alonso-MDC_s-vldl-c_pct_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	FTH1 protein levels (SeqId = 5934-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FTH1 protein levels (SeqId = 5934-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ferritin heavy chain|Ferritin light chain	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.67	0.156	0.000019	None	Gadd-DA_fth1_protein_levels__seqid___5934-1__somascan_protein_measurement
Paulina Jedynak	EDEN French birth cohort	34523531	Aug 21, 2021	Pregnancy exposure to Triclosan	CHEBI_33853	Unadjusted for cell counts	EDEN French birth cohort	DNA methylation	Pregnancy exposure to Triclosan	Age, Smoking, Batch effects, Education, center of recruitment, parity, season of conception	Beta values	None	Illumina HumanMethylation450	Placenta	None	202	1	Infants (< 4 years)	Males	European	cg12691334	chr11:68610186	11	68610186	CPT1A	North shore	0.0046	0.00108	0.000019	None	34523531_Paulina-Jedynak_pregnancy_exposure_to_triclosan_unadjusted_for_cell_counts
Battram T	GEO	29550519	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE80970	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain cortex	None	286	1	Geriatrics	Both	Unclear	cg26192826	chr11:68598649	11	68598649	CPT1A	Open sea	0.0162	0.00371	0.000019	None	29550519_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse80970
Chen Y	None	34670603	Oct 20, 2021	Waist Circumference	EFO_0004342	Multi-ethnic Asian meta-analysis	None	Waist Circumference	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	cm	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-90	21.2	0.000019	None	34670603_Chen-Y_waist_circumference_multi-ethnic_asian_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.035864	0.00838907	0.00001922741	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02146941	chr11:68522449	11	68522449	CPT1A	South shelf	0.137106	0.0320898	0.00001942567	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0352274	0.00825145	0.00001973744	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0395676	0.00927137	0.00001987266	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	-0.0352147	0.00827526	0.00002099496	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PCYOX1 protein levels (SeqId = 6431-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PCYOX1 protein levels (SeqId = 6431-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prenylcysteine oxidase 1	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.66	0.156	0.000021	None	Gadd-DA_pcyox1_protein_levels__seqid___6431-68__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.036389	0.00855289	0.00002107393	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	D6RF35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	D6RF35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0350942	0.00825149	0.00002121614	D6RF35	41361833_Josephine_Robertson_D6RF35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.046319	0.0108962	0.00002142082	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0350602	0.0082515	0.00002161016	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0409806	0.0096515	0.00002189304	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.187791	0.0442476	0.00002206152	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25464950	chr11:68600521	11	68600521	CPT1A	Open sea	-0.0350101	0.00825151	0.00002220324	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0355535	0.00838194	0.00002232198	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0458652	0.0108138	0.0000223528	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.0389661	0.00918871	0.00002242368	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Koh I-U	The Korea Epigenome Study (KES)	32788176	07-02-2020	Obesity	EFO_0001073	Replication 1	Supplementary table S7	DNA methylation	Obesity	Cell composition (reference based), Batch effects	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	373	1	Adults	Males	Unclear	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.0008	0.00019	0.000023	None	32788176_Koh-I-U_obesity_replication_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-1.8	0.415	0.000023	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.146943	0.0347021	0.00002302883	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.039331	0.0092881	0.00002303909	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0349215	0.00825154	0.00002329037	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.034914	0.00825154	0.00002338432	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0349129	0.00825154	0.00002339893	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0349016	0.00825154	0.00002354102	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12031060	chr11:68550320	11	68550320	CPT1A	Island	-0.0348948	0.00825154	0.00002362762	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0348823	0.00825155	0.00002378766	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26087005	chr11:68542540	11	68542540	CPT1A	Open sea	0.0348349	0.00824532	0.00002405942	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14411524	chr11:68583057	11	68583057	CPT1A	Open sea	-0.0348341	0.00825156	0.00002441207	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.1186422	0.0281178	0.00002449	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0348112	0.00825157	0.00002471461	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0481384	0.011412	0.00002477157	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21277192	chr11:68566812	11	68566812	CPT1A	Open sea	0.0348046	0.00825157	0.00002480308	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0481349	0.0114131	0.0000248486	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0436019	0.0103476	0.00002527163	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0347228	0.00825159	0.00002591535	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26087005	chr11:68542540	11	68542540	CPT1A	Open sea	0.0347303	0.00825337	0.00002591599	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Triglycerides in medium HDL	EFO_0004530	None	None	DNA methylation	Triglycerides in medium HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	683	1	Adults	Females	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-10.9	2.6	0.000026	None	Battram-T_triglycerides_in_medium_hdl
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10553894	chr11:68550534	11	68550534	CPT1A	Island	0.0019	None	0.000026	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0346918	0.0082516	0.00002635045	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0346916	0.0082516	0.00002635256	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0346806	0.0082516	0.00002650908	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Jia T	ENIGMA consortium	31811260	2010-12-06	Thalamus volume	None	None	Table S2	Thalamus volume	DNA methylation	Age, sex, intracranial volume, methylation composition, cell composition (reference free), batch effects, disease status	mm^3 per effect allele	Beta Values	Illumina HumanMethylation450	Whole blood	None	3337	9	Adults	Both	Unclear	cg03475843	chr11:68529097	11	68529097	CPT1A	Open sea	None	None	0.000027	None	31811260_Jia-T_thalamus_volume
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.256488	0.0611	0.0000273	-	27105112_hiv_infection_neutrophils
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0346226	0.00825162	0.00002734422	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0404056	0.00963253	0.00002748364	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.034604	0.00825163	0.0000276178	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg22345647	chr11:68609526	11	68609526	CPT1A	North shore	0.133514	0.0318425	0.00002766594	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21400885	chr11:68567699	11	68567699	CPT1A	Open sea	0.0345845	0.00825163	0.00002790766	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FTL protein levels (SeqId = 15324-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FTL protein levels (SeqId = 15324-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ferritin light chain	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.65	0.156	0.000028	None	Gadd-DA_ftl_protein_levels__seqid___15324-58__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0925636	0.0220954	0.00002814932	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0385359	0.00921215	0.00002891647	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02146941	chr11:68522449	11	68522449	CPT1A	South shelf	0.007	0.0017	0.000029	None	33450751_Mulder-RH_sex_discovery
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting insulin	EFO_0004466	Base plus BMI	Supplementary Data 1	DNA methylation	fasting insulin	Age, sex, smoking, cell composition (reference based), batch effects, body mass index	Beta Values	log pmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-1.04	0.25	0.000029	4740	31197173_Liu-J_fasting_insulin_base_plus_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0345101	0.00825165	0.00002903797	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0344283	0.0082363	0.00002931191	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0344792	0.00825166	0.00002951909	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0461381	0.0110505	0.00002994436	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.0344513	0.00825167	0.00002996115	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting insulin	EFO_0004466	Base plus BMI	Supplementary Data 1	DNA methylation	fasting insulin	Age, sex, smoking, cell composition (reference based), batch effects, body mass index	Beta Values	log pmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-1.44	0.35	0.00003	4739	31197173_Liu-J_fasting_insulin_base_plus_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0394022	0.00943824	0.00003000409	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0344326	0.00825168	0.00003026137	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Lifetime consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	None	None	0.000031	None	31789449_Dugue-P-A_alcohol_consumption_lifetime_consumption_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.190639	0.0457658	0.00003121433	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0411443	0.00987993	0.00003139147	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0343592	0.0082517	0.0000314645	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0343387	0.0082517	0.00003180945	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10970946	chr11:68540864	11	68540864	CPT1A	Open sea	0.1656	0.0398083	0.00003198582	None	39706196_Hannah-M.-Smith_bmi_discovery
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	S-VLDL-P	None	Meta-analysis	Table S2	DNA methylation	S-VLDL-P	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mol/L	Illumina HumanMethylation450	Whole blood	Concentration of small VLDL particles	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-3.9	0.93	0.000032	None	33413638_Gomez-Alonso-MDC_s-vldl-p_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	SCUBE1 protein levels (SeqId = 8989-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SCUBE1 protein levels (SeqId = 8989-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal peptide, CUB and EGF-like domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.52	0.124	0.000032	None	Gadd-DA_scube1_protein_levels__seqid___8989-40__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19596755	chr11:68609747	11	68609747	CPT1A	North shore	-0.107356	0.0258198	0.00003227263	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.043423	0.0104432	0.00003228578	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0444401	0.0106907	0.00003244176	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.0342739	0.00825172	0.00003292157	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.0348203	0.00838341	0.000032932	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_3
Mamtani M	-	26798409	2016-01-20	Hypertriglyceridemic waist	EFO_0004342, EFO_0004530	-	Table S2	Liability function of hypertriglyceridemic waist	DNA methylation	Age, sex, use of statin, use of anti-hypertensive, use of diabetic medications, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	-	850	1	46.8	Both	None	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.27949715	0.06732	0.000033	-	26798409_hypertriglyceridemic_waist
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0342404	0.00825173	0.00003351038	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0402828	0.00970862	0.00003355508	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0342322	0.00825173	0.00003365699	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0649222	0.0156501	0.00003367625	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.21847	0.0526795	0.0000338248	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.0342133	0.00825174	0.00003399438	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Leucine	EFO_0009770	None	None	DNA methylation	Leucine	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	684	1	Adults	Females	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-17.3	4.1	0.000034	None	Battram-T_leucine
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0342096	0.00825174	0.00003406097	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25464950	chr11:68600521	11	68600521	CPT1A	Open sea	-0.0341938	0.00825174	0.00003434814	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0397376	0.00959165	0.00003448098	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	0.035541	0.00857898	0.00003450149	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0341809	0.00825175	0.00003458198	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.034175	0.00825175	0.00003468983	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08242836	chr11:68572435	11	68572435	CPT1A	Open sea	0.129801	0.0313457	0.00003474831	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0341656	0.00825175	0.00003486377	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	S-VLDL-L	None	Meta-analysis	Table S2	DNA methylation	S-VLDL-L	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Total lipids in small VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-3.7	0.89	0.000035	None	33413638_Gomez-Alonso-MDC_s-vldl-l_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0341501	0.00825176	0.00003514997	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0395933	0.00958474	0.00003633963	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_4
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	M-VLDL-P	None	Meta-analysis	Table S2	DNA methylation	M-VLDL-P	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mol/L	Illumina HumanMethylation450	Whole blood	Concentration of medium VLDL particles	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-6.1	1.47	0.000037	None	33413638_Gomez-Alonso-MDC_m-vldl-p_meta-analysis
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.104236	0.0252821	0.00003757751	None	39706196_Hannah-M.-Smith_glucose_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.0379071	0.00919575	0.00003772699	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Lifetime consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	None	None	0.000038	None	31789449_Dugue-P-A_alcohol_consumption_lifetime_consumption_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	0.0014	None	0.000038	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26087005	chr11:68542540	11	68542540	CPT1A	Open sea	0.0339976	0.0082518	0.000038091	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0351705	0.00854556	0.00003881977	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0338722	0.00825183	0.00004068432	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Nicolas Fragoso-Bargas	EPIPREG	36534481	Dec 19, 2022	HOMA-IR	EFO:0000001	discovery (european)	Supplementary Table 3	DNA methylation	HOMA-IR	Age,Smoking,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	analysis in pregnancy (europeans)	294	1	Adults (18-65 years)	Females	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.157998698	0.038068085	0.0000407	None	36534481_Nicolas-Fragoso-Bargas_homa-ir_discovery_(european)
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg20629021	chr11:68580041	11	68580041	CPT1A	Open sea	0.195658	0.0476751	0.00004078614	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Battram T	ARIES	None	2020-08-20	Total cholesterol in chylomicrons and extremely large VLDL	EFO_0004574	None	None	DNA methylation	Total cholesterol in chylomicrons and extremely large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	661	1	Adults	Females	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	38	9.1	0.000041	None	Battram-T_total_cholesterol_in_chylomicrons_and_extremely_large_vldl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0338504	0.00825184	0.00004115116	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.0338474	0.00825184	0.00004121521	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0394367	0.00962102	0.00004171488	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0343738	0.00839033	0.00004210854	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0355318	0.00867533	0.00004230952	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting glucose	EFO_0004465	Base	Supplementary Data 1	DNA methylation	fasting glucose	Age, sex, smoking, cell composition (reference based), batch effects	Beta Values	mmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.97	0.24	0.000043	4808	31197173_Liu-J_fasting_glucose_base
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.0337654	0.00825186	0.0000430236	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	0.0337649	0.00825186	0.00004303376	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.152873	0.0373677	0.00004313674	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	0.0337258	0.00825187	0.00004392157	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0627759	0.0153651	0.0000441939	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.0337092	0.00825188	0.00004430565	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0336929	0.00825188	0.00004468286	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_1
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	M-VLDL-L	None	Meta-analysis	Table S2	DNA methylation	M-VLDL-L	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Total lipids in medium VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-6	1.46	0.000045	None	33413638_Gomez-Alonso-MDC_m-vldl-l_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0337729	0.00828204	0.00004569393	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09972762	chr11:68553421	11	68553421	CPT1A	South shelf	-0.0024	0.00058	0.000046	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	0.0336347	0.0082519	0.0000460598	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0336278	0.0082519	0.00004622595	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.037534	0.00921839	0.00004692744	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0374282	0.00919277	0.0000469599	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Battram T	GEO	25282492	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE61278. Compared fetal liver tissue to adult liver tissue of different individuals	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Fetal liver, adult liver	None	110	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.275	0.064	0.000047	None	25282492_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse61278__compared_fetal_liver_tissue_to_adult_liver_tissue_of_different_individuals
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.141367	0.0347377	0.00004730014	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0522792	0.0128551	0.00004791167	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0335514	0.00825192	0.00004809829	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0382041	0.00939989	0.00004842557	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0387856	0.00954594	0.00004868858	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0391399	0.00963484	0.00004883836	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14391	1	Adults (18-65y)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.068	0.01674	0.000049	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Fully-adjusted_model
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Discovery	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	653	1	48	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-38.42	9.41	0.0000498	-	27777315_postprandial_lipemia_discovery
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Replication adjusted for baseline triglycerides	Table S1	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	326	1	48.8	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-13.99	3.4	0.00005	-	27777315_postprandial_lipemia_replication_adjusted_for_baseline_triglycerides
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13971	1	Adults (18-65y)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	-0.023	0.00571	0.00005	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Fully-adjusted_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15211864	chr11:68531232	11	68531232	CPT1A	Open sea	0.142325	0.0350935	0.00005022644	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21400885	chr11:68567699	11	68567699	CPT1A	Open sea	0.0333434	0.0082253	0.00005066151	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0380029	0.00937755	0.00005092591	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	S-VLDL-FC	None	Meta-analysis	Table S2	DNA methylation	S-VLDL-FC	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Free cholesterol in small VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-3.6	0.9	0.000051	None	33413638_Gomez-Alonso-MDC_s-vldl-fc_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3BP2 protein levels (SeqId = 7769-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3BP2 protein levels (SeqId = 7769-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SH3 domain-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.59	0.147	0.000051	None	Gadd-DA_sh3bp2_protein_levels__seqid___7769-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0334384	0.00825195	0.00005100345	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0389539	0.00961324	0.0000510196	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	0.0336932	0.00832008	0.0000515628	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0334167	0.00825196	0.00005158084	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg15211864	chr11:68531232	11	68531232	CPT1A	Open sea	0.859895	0.2125	0.0000519	-	27105112_hiv_infection_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	PES1 protein levels (SeqId = 4267-81)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PES1 protein levels (SeqId = 4267-81)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pescadillo homolog	774	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.59	0.147	0.000052	None	Gadd-DA_pes1_protein_levels__seqid___4267-81__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25890640	chr11:68610632	11	68610632	CPT1A	North shore	0.00023	0.000058	0.000052	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg13227195	chr11:68571630	11	68571630	CPT1A	Open sea	0.186926	0.0462043	0.00005240521	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0339462	0.0083933	0.00005271697	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0461365	0.0114098	0.00005290632	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.0333589	0.00825198	0.0000531464	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20629021	chr11:68580041	11	68580041	CPT1A	Open sea	0.0396531	0.00981232	0.00005346146	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0333337	0.00825198	0.00005384351	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	M-VLDL-FC	None	Meta-analysis	Table S2	DNA methylation	M-VLDL-FC	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Free cholesterol in medium VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-7	1.73	0.000054	None	33413638_Gomez-Alonso-MDC_m-vldl-fc_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20629021	chr11:68580041	11	68580041	CPT1A	Open sea	-0.0333255	0.00825199	0.00005407226	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0375382	0.00930436	0.00005500326	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0332818	0.008252	0.000055304	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0332798	0.008252	0.00005536287	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0390471	0.00968314	0.00005546951	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0419749	0.0104138	0.00005589036	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	C9JB55	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	C9JB55	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0633594	0.0157202	0.0000559523	C9JB55	41361833_Josephine_Robertson_C9JB55_OSCA_model_4
Paulina Jedynak	EDEN French birth cohort	34523531	Aug 21, 2021	Pregnancy exposure to Triclosan	CHEBI_33853	Adjusted for cell composition	EDEN French birth cohort	DNA methylation	Pregnancy exposure to Triclosan	Age, Smoking, Batch effects, Education, Cell composition (reference based), center of recruitment, parity, season of conception	Beta values	None	Illumina HumanMethylation450	Placenta	None	202	1	Infants (< 4 years)	Males	European	cg12691334	chr11:68610186	11	68610186	CPT1A	North shore	0.0037	0.00092	0.000056	None	34523531_Paulina-Jedynak_pregnancy_exposure_to_triclosan_adjusted_for_cell_composition
Battram T	ARIES	None	2020-08-20	Total cholesterol in very large VLDL	EFO_0004574	None	None	DNA methylation	Total cholesterol in very large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	646	1	Adults	Females	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	12.3	3	0.000056	None	Battram-T_total_cholesterol_in_very_large_vldl
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.097	0.024	0.000056	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0332406	0.00825201	0.000056494	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0615004	0.0152697	0.0000566335	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0332354	0.00825201	0.00005664543	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13971	1	Adults (18-65y)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.044	0.01095	0.000057	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0332165	0.00825202	0.00005719771	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.103305	0.0256733	0.00005750514	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.033205	0.00825202	0.0000575386	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0407006	0.0101161	0.00005766431	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0397634	0.00988351	0.00005769857	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0418423	0.0104024	0.00005790737	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0370991	0.00922616	0.00005822119	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0383687	0.00954654	0.0000587082	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0387616	0.00964561	0.00005884286	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0376986	0.00938476	0.00005923738	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.06054	0.0150859	0.00006024365	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	WNT5A protein levels (SeqId = 13268-45)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WNT5A protein levels (SeqId = 13268-45)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein Wnt-5a	774	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.5	0.124	0.000061	None	Gadd-DA_wnt5a_protein_levels__seqid___13268-45__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMD5 protein levels (SeqId = 10716-35)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMD5 protein levels (SeqId = 10716-35)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 26S proteasome non-ATPase regulatory subunit 5	774	1	Adults (18-65 years)	Both	European	cg03934937	chr11:68598134	11	68598134	CPT1A	Open sea	-0.61	0.152	0.000061	None	Gadd-DA_psmd5_protein_levels__seqid___10716-35__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0330869	0.00825205	0.00006114032	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0383263	0.00956257	0.00006155214	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20629021	chr11:68580041	11	68580041	CPT1A	Open sea	0.0330651	0.00825206	0.00006182616	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0330421	0.00825206	0.00006256133	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14249520	chr11:68530177	11	68530177	CPT1A	Open sea	-0.0330288	0.00825207	0.00006298871	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0330276	0.00825207	0.00006302599	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	-0.0325241	0.00812836	0.00006330043	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0383522	0.00958884	0.00006374305	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.038252	0.00956498	0.00006387557	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0342284	0.00855902	0.0000638936	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	0.123512	0.0308885	0.00006395835	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0535564	0.0133968	0.00006426995	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0385548	0.00964493	0.00006434979	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06292310	chr11:68581324	11	68581324	CPT1A	Open sea	0.049902	0.0124861	0.00006456981	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0330496	0.0082704	0.00006469971	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0414959	0.0103867	0.00006498051	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	CASP8 protein levels (SeqId = 18158-45)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASP8 protein levels (SeqId = 18158-45)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Caspase-8	774	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.59	0.147	0.000065	None	Gadd-DA_casp8_protein_levels__seqid___18158-45__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg26087005	chr11:68542540	11	68542540	CPT1A	Open sea	-0.117285	0.0293612	0.00006507574	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.032945	0.00825209	0.00006574789	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.032935	0.00825209	0.0000660835	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14411524	chr11:68583057	11	68583057	CPT1A	Open sea	-0.0331643	0.00831086	0.0000662611	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0328786	0.00825211	0.00006801568	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0328778	0.00825211	0.00006804264	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0328745	0.00825211	0.00006815837	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	-0.0517769	0.0129997	0.0000684011	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0384523	0.00965637	0.00006864789	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0328533	0.00825211	0.00006889972	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.200394	0.0503527	0.00006925533	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0386226	0.00970582	0.00006944435	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0366254	0.00920418	0.00006947592	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0328315	0.00825212	0.00006966979	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.03283	0.00825212	0.00006972097	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19827	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P19827	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0412898	0.0103787	0.00006973914	P19827	41361833_Josephine_Robertson_P19827_OSCA_model_2
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	M-VLDL-C	None	Meta-analysis	Table S2	DNA methylation	M-VLDL-C	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Total cholesterol in medium VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-4.8	1.21	0.00007	None	33413638_Gomez-Alonso-MDC_m-vldl-c_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.0350349	0.00880872	0.00007003925	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0383698	0.00964896	0.00007025075	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21400885	chr11:68567699	11	68567699	CPT1A	Open sea	0.0325815	0.0081936	0.00007028673	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0328103	0.00825213	0.00007042499	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	Ile	EFO_0009793	Meta-analysis	Table S2	DNA methylation	Ile	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Isoleucine	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-1.47	0.371	0.000071	None	33413638_Gomez-Alonso-MDC_ile_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.0327699	0.00825214	0.00007188727	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	Serum-TG	EFO_0004530	Meta-analysis	Table S2	DNA methylation	Serum-TG	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Serum total triglycerides	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-5.1	1.28	0.000072	None	33413638_Gomez-Alonso-MDC_serum-tg_meta-analysis
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg15211864	chr11:68531232	11	68531232	CPT1A	Open sea	0.024	0.00616	0.000075	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	0.0326858	0.00825216	0.00007502834	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0385982	0.00974573	0.00007514047	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01703	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01703	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0364925	0.00921507	0.00007527571	P01703	41361833_Josephine_Robertson_P01703_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.0326706	0.00825216	0.0000756088	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	-0.03788	0.00956934	0.00007578458	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Gomez-Alonso MDC	KORA F4	33413638	2021-01-07	M-VLDL-PL	None	Meta-analysis	Table S2	DNA methylation	M-VLDL-PL	Age, sex, smoking, body mass index, CRP, HbA1c, alcohol consumption, lipid-lowering drugs, hypertension, history of myocardial infarction, level of physical activity, cell composition (reference based)	Beta Values	mmol/L	Illumina HumanMethylation450	Whole blood	Phospholipids in medium VLDL	5414	4	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-5.7	1.43	0.000076	None	33413638_Gomez-Alonso-MDC_m-vldl-pl_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0399429	0.0100978	0.00007669633	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	0.032638	0.00825217	0.00007686983	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15748291	chr11:68567642	11	68567642	CPT1A	Open sea	0.0326116	0.00825218	0.00007790272	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0337452	0.00854024	0.0000780846	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19827	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P19827	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0410531	0.0103919	0.0000783567	P19827	41361833_Josephine_Robertson_P19827_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0419145	0.0106104	0.00007840888	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15748291	chr11:68567642	11	68567642	CPT1A	Open sea	-0.214307	0.0542633	0.00007864412	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Inflammatory Bowel Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Inflammatory Bowel Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17959	1	Adults (18-65y)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.016	0.00395	0.000079	None	Robert-F-Hillary_Incident_Inflammatory_Bowel_Disease_Basic_model
Battram T	ARIES	None	2020-08-20	Saturated fatty acids	EFO_0005110	None	None	DNA methylation	Saturated fatty acids	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	669	1	Adults	Females	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.187	0.047	0.000079	None	Battram-T_saturated_fatty_acids
Gadd DA	Generation Scotland	35945220	31/07/2022	KLF4 protein levels (SeqId = 17850-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLF4 protein levels (SeqId = 17850-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Krueppel-like factor 4	774	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.58	0.147	0.000079	None	Gadd-DA_klf4_protein_levels__seqid___17850-42__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.032575	0.00825219	0.00007936221	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.0325744	0.00825219	0.00007938554	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.041117	0.0104184	0.00007964479	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	-0.0396757	0.0100557	0.00007997823	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.073	0.0185	0.00008	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	-0.0325543	0.0082522	0.00008019458	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	0.0889316	0.0225529	0.00008075862	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.192205	0.0487521	0.00008094052	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0379599	0.00963124	0.00008140638	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.0361541	0.00918063	0.00008251512	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_2
Battram T	GEO	27886173	2020-09-15	Inflammatory bowel disease	EFO_0003767	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Inflammatory bowel disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	240	1	Adults	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0198	0.00494	0.000083	None	27886173_Battram-T_inflammatory_bowel_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05325763	chr11:68607719	11	68607719	CPT1A	South shore	0.0447709	0.0113779	0.00008361033	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.120645	0.0306627	0.0000836689	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0429326	0.0109118	0.00008375386	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0381442	0.00969647	0.00008398971	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CST5 protein levels (SeqId = 3803-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CST5 protein levels (SeqId = 3803-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cystatin-D	774	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	0.57	0.146	0.000084	None	Gadd-DA_cst5_protein_levels__seqid___3803-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHH protein levels (SeqId = 2743-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHH protein levels (SeqId = 2743-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sonic hedgehog protein	774	1	Adults (18-65 years)	Both	European	cg14443077	chr11:68606701	11	68606701	CPT1A	Island	-0.51	0.129	0.000084	None	Gadd-DA_shh_protein_levels__seqid___2743-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0381009	0.00968883	0.00008446863	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18708425	chr11:68566745	11	68566745	CPT1A	Open sea	0.0396515	0.0100853	0.00008476638	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	0.0379113	0.00964504	0.0000851036	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15748291	chr11:68567642	11	68567642	CPT1A	Open sea	0.0328678	0.00836714	0.00008597715	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.0324857	0.0082704	0.00008606704	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	-0.228461	0.0581694	0.00008615974	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0324079	0.00825223	0.00008634729	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FUT3 protein levels (SeqId = 4548-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FUT3 protein levels (SeqId = 4548-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Galactoside 3(4)-L-fucosyltransferase	774	1	Adults (18-65 years)	Both	European	cg03855388	chr11:68580018	11	68580018	CPT1A	Open sea	0.52	0.133	0.000087	None	Gadd-DA_fut3_protein_levels__seqid___4548-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.0524731	0.0133746	0.00008772444	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	0.0407155	0.010381	0.00008817	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0323542	0.00825225	0.00008871019	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	0.0323478	0.00825225	0.00008899539	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12691334	chr11:68610186	11	68610186	CPT1A	North shore	-0.0328833	0.00839086	0.00008934219	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09277116	chr11:68589533	11	68589533	CPT1A	Open sea	0.0323348	0.00825225	0.00008957832	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg15169934	chr11:68561347	11	68561347	CPT1A	Open sea	0.147196	0.0375725	0.00008974633	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05909614	chr11:68541485	11	68541485	CPT1A	Open sea	-0.120343	0.030733	0.00009046865	None	39706196_Hannah-M.-Smith_body_fat_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	KAZALD1 protein levels (SeqId = 7144-234)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KAZALD1 protein levels (SeqId = 7144-234)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kazal-type serine protease inhibitor domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.61	0.156	0.000091	None	Gadd-DA_kazald1_protein_levels__seqid___7144-234__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0322867	0.00825227	0.00009176953	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23756264	chr11:68605511	11	68605511	CPT1A	North shore	-0.0322612	0.00825227	0.00009295305	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Glycoprotein acetyls	EFO_0004555	None	None	DNA methylation	Glycoprotein acetyls	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	683	1	Adults	Females	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.91	0.23	0.000093	None	Battram-T_glycoprotein_acetyls
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20809737	chr11:68574649	11	68574649	CPT1A	Open sea	0.0322588	0.00825227	0.00009306349	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg26989316	chr11:68607257	11	68607257	CPT1A	Island	-0.146512	0.037484	0.00009315038	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22911054	chr11:68603379	11	68603379	CPT1A	North shelf	0.0381657	0.0097682	0.00009381328	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Arm region fat	EFO_0005409	None	None	DNA methylation	Arm region fat	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	706	1	Adults	Females	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-1.73	0.44	0.000094	None	Battram-T_arm_region_fat
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	-0.0322347	0.00825228	0.00009419823	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13862013	chr11:68549689	11	68549689	CPT1A	North shore	-0.0322289	0.00825228	0.00009447067	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg17056629	chr11:68566777	11	68566777	CPT1A	Open sea	0.161785	0.0414383	0.00009486302	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	-0.0317372	0.0081327	0.00009566354	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	GMPR protein levels (SeqId = 19254-125)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GMPR protein levels (SeqId = 19254-125)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GMP reductase 1	774	1	Adults (18-65 years)	Both	European	cg01082498	chr11:68608225	11	68608225	CPT1A	Island	-0.57	0.146	0.000096	None	Gadd-DA_gmpr_protein_levels__seqid___19254-125__somascan_protein_measurement
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting insulin	EFO_0004466	Base plus BMI	Supplementary Data 1	DNA methylation	fasting insulin	Age, sex, smoking, cell composition (reference based), batch effects, body mass index	Beta Values	log pmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg20285002	chr11:68583898	11	68583898	CPT1A	Open sea	-2.88	0.74	0.000096	4738	31197173_Liu-J_fasting_insulin_base_plus_bmi
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15211864	chr11:68531232	11	68531232	CPT1A	Open sea	-0.0335304	0.00859485	0.00009613499	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg13227195	chr11:68571630	11	68571630	CPT1A	Open sea	0.180581	0.0463116	0.0000968562	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12323168	chr11:68593365	11	68593365	CPT1A	Open sea	-0.0344182	0.00883246	0.00009791154	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22451063	chr11:68541579	11	68541579	CPT1A	Open sea	0.0321559	0.0082523	0.00009798506	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	0.0321466	0.00825243	0.00009846967	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_3
Priyanka Choudhary	PACE	38052982	Dec 5, 2023	Maternal education at the time of pregnancy	None	Model2_Adolescence	None	DNA methylation	Maternal education at the time of pregnancy	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Body mass index, Gestational age	Beta values	years of schooling	Illumina HumanMethylation450	Whole blood	Illumina HumanMethylationEPIC was also used for some cohorts	2740	None	Children	Both	European	cg18262591	chr11:68579970	11	68579970	CPT1A	Open sea	-0.00024	0.000063	0.000099	None	38052982_Priyanka-Choudhary_maternal_education_at_the_time_of_pregnancy_model2_adolescence
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05145442	chr11:68551729	11	68551729	CPT1A	South shore	0.0382634	0.00982821	0.00009936105	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09737197	chr11:68607675	11	68607675	CPT1A	North shore	-0.0424654	0.0109118	0.00009998983	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4