author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00321709	chr10:135341933	10	135341933	CYP2E1	Island	-0.0028	0.00028	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00436603	chr10:135340740	10	135340740	CYP2E1	North shore	-0.029	0.0023	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01465364	chr10:135340721	10	135340721	CYP2E1	North shore	-0.027	0.0018	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19571004	chr10:135340850	10	135340850	CYP2E1	North shore	-0.03	0.0025	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19837601	chr10:135340871	10	135340871	CYP2E1	North shore	-0.024	0.0027	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21024264	chr10:135341025	10	135341025	CYP2E1	North shore	-0.024	0.0023	0	None	33450751_Mulder-RH_sex_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10986462	chr10:135340539	10	135340539	CYP2E1	North shore	0.39629	0.01398	1.1e-70	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19571004	chr10:135340850	10	135340850	CYP2E1	North shore	0.20255	0.00718	2e-70	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07381788	chr10:135340445	10	135340445	CYP2E1	North shore	0.28065	0.01207	7.2e-58	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01465364	chr10:135340721	10	135340721	CYP2E1	North shore	0.18654	0.00809	2.3e-57	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg09208540	chr10:135340467	10	135340467	CYP2E1	North shore	0.34681	0.01534	3.9999999999999997e-56	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21024264	chr10:135341025	10	135341025	CYP2E1	North shore	0.16433	0.00729	5.8e-56	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg00436603	chr10:135340740	10	135340740	CYP2E1	North shore	0.13087	0.00657	1.1e-48	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14250048	chr10:135340785	10	135340785	CYP2E1	North shore	0.17695	0.00927	2.5e-46	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg07381788	chr10:135340445	10	135340445	CYP2E1	North shore	2.71532	0.10212	1.5300000000000001e-43	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg09208540	chr10:135340467	10	135340467	CYP2E1	North shore	2.4521	0.11825	2.01e-35	-	25282492_fetal_vs_adult_liver
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg14250048	chr10:135340785	10	135340785	CYP2E1	North shore	-	-	8.83e-34	-	23526956_clear_cell_renal_carcinoma
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg19571004	chr10:135340850	10	135340850	CYP2E1	North shore	1.71369	0.0889	3.72e-33	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg00436603	chr10:135340740	10	135340740	CYP2E1	North shore	1.54643	0.08405	9.77e-32	-	25282492_fetal_vs_adult_liver
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg01465364	chr10:135340721	10	135340721	CYP2E1	North shore	-	-	3.1100000000000003e-31	-	23526956_clear_cell_renal_carcinoma
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg19837601	chr10:135340871	10	135340871	CYP2E1	North shore	1.92792	0.10838	9.99e-31	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg01465364	chr10:135340721	10	135340721	CYP2E1	North shore	1.63408	0.09775	6.64e-29	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg21024264	chr10:135341025	10	135341025	CYP2E1	North shore	1.80758	0.10855	8.61e-29	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg14250048	chr10:135340785	10	135340785	CYP2E1	North shore	1.66262	0.10311	7.19e-28	-	25282492_fetal_vs_adult_liver
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg10986462	chr10:135340539	10	135340539	CYP2E1	North shore	-	-	2.34e-25	-	23526956_clear_cell_renal_carcinoma
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19837601	chr10:135340871	10	135340871	CYP2E1	North shore	0.08645	0.00735	2.0000000000000002e-24	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27214960	chr10:135343280	10	135343280	CYP2E1	South shore	0.0022	None	1.7e-20	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg16538390	chr10:135344917	10	135344917	CYP2E1	South shelf	-0.02715	0.00294	5e-17	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11445109	chr10:135343248	10	135343248	CYP2E1	South shore	0.0021	None	0.000000000000036	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10986462	chr10:135340539	10	135340539	CYP2E1	North shore	-0.0087	0.0012	0.000000000000095	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14250048	chr10:135340785	10	135340785	CYP2E1	North shore	-0.014	0.0019	0.0000000000004	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19837601	chr10:135340871	10	135340871	CYP2E1	North shore	0.0022	None	0.0000000000051	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19469447	chr10:135341870	10	135341870	CYP2E1	Island	-0.0012	0.00018	0.000000000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09208540	chr10:135340467	10	135340467	CYP2E1	North shore	-0.00069	0.0001	0.000000000035	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg01465364	chr10:135340721	10	135340721	CYP2E1	North shore	-	-	0.0000000000752	-	26500701_sex_kora_f4
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg00436603	chr10:135340740	10	135340740	CYP2E1	North shore	-	-	0.000000000978	-	26500701_sex_kora_f4
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg07381788	chr10:135340445	10	135340445	CYP2E1	North shore	0.0215	0.00331	0.0000000013	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18984983	chr10:135342936	10	135342936	CYP2E1	South shore	-0.00091	0.00015	0.0000000035	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19837601	chr10:135340871	10	135340871	CYP2E1	North shore	-0.0015	0.00026	0.0000000049	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19721068	chr10:135346592	10	135346592	CYP2E1	Open sea	0.046282	0.00824772	0.0000000204218	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07381788	chr10:135340445	10	135340445	CYP2E1	North shore	-0.0006	0.00011	0.000000059	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19721068	chr10:135346592	10	135346592	CYP2E1	Open sea	-0.0444932	0.00824839	0.00000006990986	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18984983	chr10:135342936	10	135342936	CYP2E1	South shore	0.0014	None	0.00000009	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19721068	chr10:135346592	10	135346592	CYP2E1	Open sea	0.0419012	0.00824932	0.0000003833714	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16538390	chr10:135344917	10	135344917	CYP2E1	South shelf	0.0065	0.0013	0.00000081	None	33450751_Mulder-RH_sex_discovery
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg13315147	chr10:135341528	10	135341528	CYP2E1	Island	0.1432	0.02864	0.0000014	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg10862468	chr10:135342218	10	135342218	CYP2E1	Island	0.1189	0.02389	0.0000016	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg19469447	chr10:135341870	10	135341870	CYP2E1	Island	0.1236	0.02483	0.0000016	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Gondalia R.	WHI, ARC	31208937	2019-06-14	Particulate matter ≤10 um (PM10)	EFO_0008255	Discovery and replication	Table S3	DNA methylation	Particulate matter ≤10 um (PM10)	Age, educational attainment, smoking, alcohol consumption, physical activity, body mass index, socioeconomic position, sex	Other	um	Illumina HumanMethylation450	Whole Blood	Some study-specific covariates	8397	2	Adults	Both	African, European, Admixed	cg25330361	chr10:135342413	10	135342413	CYP2E1	Island	0.00099	0.00021	0.0000019	Particulate matter ?10 ?m (PM10)	31208937_Gondalia-R._particulate_matter_≤10_um__pm10__discovery_and_replication
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age*sex	PATO_0000047,EFO_0000246	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	age*sex	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14250048	chr10:135340785	10	135340785	CYP2E1	North shore	0.00094	0.0002	0.000002	None	33450751_Mulder-RH_age_sex_discovery
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg18984983	chr10:135342936	10	135342936	CYP2E1	South shore	0.1035	0.02099	0.000002	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg21024264	chr10:135341025	10	135341025	CYP2E1	North shore	-	-	0.0000022	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19721068	chr10:135346592	10	135346592	CYP2E1	Open sea	-0.0389719	0.0082503	0.000002337375	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg01465364	chr10:135340721	10	135340721	CYP2E1	North shore	0.0332	0.0068	0.0000024	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg11445109	chr10:135343248	10	135343248	CYP2E1	South shore	0.1223	0.02503	0.0000024	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg14250048	chr10:135340785	10	135340785	CYP2E1	North shore	0.0272	0.00561	0.0000028	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg00321709	chr10:135341933	10	135341933	CYP2E1	Island	-0.4250061	0.0914821	0.000003388	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg23400446	chr10:135342560	10	135342560	CYP2E1	Island	0.1172	0.02454	0.0000039	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Battram T	GEO	27886173	2020-09-15	Inflammatory bowel disease	EFO_0003767	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Inflammatory bowel disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	240	1	Adults	Both	European	cg01465364	chr10:135340721	10	135340721	CYP2E1	North shore	-0.0204	0.00433	0.0000044	None	27886173_Battram-T_inflammatory_bowel_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16538390	chr10:135344917	10	135344917	CYP2E1	South shelf	0.00057	0.00012	0.0000051	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg24530264	chr10:135342620	10	135342620	CYP2E1	South shore	0.0937	0.02018	0.0000069	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg00321709	chr10:135341933	10	135341933	CYP2E1	Island	0.1353	0.0294	0.0000083	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Gadd DA	Generation Scotland	35945220	31/07/2022	RBL1 protein levels (SeqId = 12879-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RBL1 protein levels (SeqId = 12879-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Retinoblastoma-like protein 1	774	1	Adults (18-65 years)	Both	European	cg05194426	chr10:135343193	10	135343193	CYP2E1	South shore	0.14	0.031	0.0000087	None	Gadd-DA_rbl1_protein_levels__seqid___12879-5__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10986462	chr10:135340539	10	135340539	CYP2E1	North shore	-0.00045	0.0001	0.0000088	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg14250048	chr10:135340785	10	135340785	CYP2E1	North shore	0.0188	0.0041	0.00001	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05417377	chr10:135350807	10	135350807	CYP2E1	Open sea	0.0362635	0.00825114	0.00001115692	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	27886173	2020-09-15	Inflammatory bowel disease	EFO_0003767	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Inflammatory bowel disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	240	1	Adults	Both	European	cg07381788	chr10:135340445	10	135340445	CYP2E1	North shore	-0.0148	0.00333	0.000015	None	27886173_Battram-T_inflammatory_bowel_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09208540	chr10:135340467	10	135340467	CYP2E1	North shore	0.0007	None	0.000015	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg25330361	chr10:135342413	10	135342413	CYP2E1	Island	0.0375	0.0084	0.000015	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05194426	chr10:135343193	10	135343193	CYP2E1	South shore	-0.08243	0.0186	0.000016	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19571004	chr10:135340850	10	135340850	CYP2E1	North shore	0.0016	None	0.000017	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25330361	chr10:135342413	10	135342413	CYP2E1	Island	-0.00024	0.000055	0.00002	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	REG3A protein levels (SeqId = 15304-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	REG3A protein levels (SeqId = 15304-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Regenerating islet-derived protein 3-alpha	774	1	Adults (18-65 years)	Both	European	cg00436603	chr10:135340740	10	135340740	CYP2E1	North shore	-0.44	0.103	0.000023	None	Gadd-DA_reg3a_protein_levels__seqid___15304-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19721068	chr10:135346592	10	135346592	CYP2E1	Open sea	0.0348985	0.00825154	0.00002358078	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19721068	chr10:135346592	10	135346592	CYP2E1	Open sea	-0.0348703	0.00825155	0.0000239422	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Battram T	GEO	27886173	2020-09-15	Inflammatory bowel disease	EFO_0003767	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Inflammatory bowel disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	240	1	Adults	Both	European	cg14250048	chr10:135340785	10	135340785	CYP2E1	North shore	-0.0161	0.00378	0.00003	None	27886173_Battram-T_inflammatory_bowel_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg05194426	chr10:135343193	10	135343193	CYP2E1	South shore	0.0991	0.02324	0.000033	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg01465364	chr10:135340721	10	135340721	CYP2E1	North shore	0.0187	0.00444	0.000044	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19721068	chr10:135346592	10	135346592	CYP2E1	Open sea	0.0335937	0.00825191	0.00004705392	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26065573	chr10:135339469	10	135339469	CYP2E1	North shore	0.0334893	0.00825194	0.00004967483	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F3	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	53	Both	European	cg00436603	chr10:135340740	10	135340740	CYP2E1	North shore	-	-	0.0000502	-	26500701_sex_kora_f3
Gadd DA	Generation Scotland	35945220	31/07/2022	RBL1 protein levels (SeqId = 12879-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RBL1 protein levels (SeqId = 12879-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Retinoblastoma-like protein 1	774	1	Adults (18-65 years)	Both	European	cg11445109	chr10:135343248	10	135343248	CYP2E1	South shore	0.09	0.022	0.000051	None	Gadd-DA_rbl1_protein_levels__seqid___12879-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RBL1 protein levels (SeqId = 12879-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RBL1 protein levels (SeqId = 12879-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Retinoblastoma-like protein 1	774	1	Adults (18-65 years)	Both	European	cg23400446	chr10:135342560	10	135342560	CYP2E1	Island	0.12	0.029	0.000055	None	Gadd-DA_rbl1_protein_levels__seqid___12879-5__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05194426	chr10:135343193	10	135343193	CYP2E1	South shore	0.0025	None	0.000056	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10986462	chr10:135340539	10	135340539	CYP2E1	North shore	-0.0329554	0.00825209	0.00006539979	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg00436603	chr10:135340740	10	135340740	CYP2E1	North shore	0.0322	0.00792	0.000073	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age*sex	PATO_0000047,EFO_0000246	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	age*sex	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01465364	chr10:135340721	10	135340721	CYP2E1	North shore	0.00066	0.00017	0.000076	None	33450751_Mulder-RH_age_sex_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	WFIKKN1 protein levels (SeqId = 3191-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WFIKKN1 protein levels (SeqId = 3191-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg05194426	chr10:135343193	10	135343193	CYP2E1	South shore	0.123	0.031	0.000083	None	Gadd-DA_wfikkn1_protein_levels__seqid___3191-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RBL1 protein levels (SeqId = 12879-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RBL1 protein levels (SeqId = 12879-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Retinoblastoma-like protein 1	774	1	Adults (18-65 years)	Both	European	cg18984983	chr10:135342936	10	135342936	CYP2E1	South shore	0.12	0.029	0.000085	None	Gadd-DA_rbl1_protein_levels__seqid___12879-5__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age*sex	PATO_0000047,EFO_0000246	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	age*sex	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19571004	chr10:135340850	10	135340850	CYP2E1	North shore	0.001	0.00027	0.000085	None	33450751_Mulder-RH_age_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19721068	chr10:135346592	10	135346592	CYP2E1	Open sea	-0.0324236	0.00825223	0.00008566668	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01355198	chr10:135347330	10	135347330	CYP2E1	Open sea	-0.0322234	0.00827387	0.00009879885	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	WFIKKN1 protein levels (SeqId = 3191-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WFIKKN1 protein levels (SeqId = 3191-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg11445109	chr10:135343248	10	135343248	CYP2E1	South shore	0.086	0.022	0.000099	None	Gadd-DA_wfikkn1_protein_levels__seqid___3191-50__somascan_protein_measurement