author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04112704	chr14:95608514	14	95608514	DICER1	Open sea	0.002	0.00019	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10948630	chr14:95562368	14	95562368	DICER1	Open sea	-0.0019	0.00016	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	-0.30293	0.00623	3.4e-110	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.49761	0.0103	9.900000000000001e-110	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23899649	chr14:95553486	14	95553486	DICER1	Open sea	0.16911	0.00367	3.4000000000000003e-106	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	-3.11629	0.05578	6.08e-70	-	25282492_fetal_vs_adult_liver
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04112704	chr14:95608514	14	95608514	DICER1	Open sea	0.07812	0.00473	8.699999999999999e-39	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	-	-	2.1200000000000002e-33	-	28056824_age_4_vs_age_0
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Discovery	Table S3, Table S4	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	879	2	12	Both	European,African,Other	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-6.2	0.5258	4.3000000000000004e-32	-	28069425_total_serum_ige_discovery
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	1.05581667	0.0943	4.2e-29	-	25888029_ageing
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0870556	0.00822523	4.39126e-26	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PRG3 protein levels (SeqId = 9015-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRG3 protein levels (SeqId = 9015-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteoglycan 3	774	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-1.96	0.192	1.8999999999999998e-24	None	Gadd-DA_prg3_protein_levels__seqid___9015-1__somascan_protein_measurement
Chen W	-	28069425	2017-01-06	Total serum IgE	EFO_0004579	Puerto Ricans only	Table E7	Total serum IgE	DNA methylation	Age, sex, asthma and technical covariates	IU/ml	Beta values	Illumina HumanMethylation450	Whole blood	Total serum IgE was log10 transformed	525	2	12	Both	European,African,Other	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-6.02	0.6024	1.6399999999999998e-23	-	28069425_total_serum_ige_puerto_ricans_only
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPPA protein levels (SeqId = 4148-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPPA protein levels (SeqId = 4148-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pappalysin-1	774	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-1.81	0.191	2.6e-21	None	Gadd-DA_pappa_protein_levels__seqid___4148-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0776564	0.00823164	4.53352e-21	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	ch.14.1558261F	chr14:95593869	14	95593869	DICER1	Open sea	0.01716	0.00164	1.6e-20	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10948630	chr14:95562368	14	95562368	DICER1	Open sea	0.0014	None	3.3e-20	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.01911	0.00188	1e-19	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23488578	chr14:95585023	14	95585023	DICER1	Open sea	0.001	None	2.1e-17	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Xu C-J	MeDALL	29496485	2018-02-26	Asthma	EFO_0000270	Meta-analysis of discovery and replication at age 8	Table 1	DNA methylation	Asthma	Sex, batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	3927	8	Children	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.018	0.0022	2.6e-17	None	29496485_Xu-C-J_asthma_meta-analysis_of_discovery_and_replication_at_age_8
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg23488578	chr14:95585023	14	95585023	DICER1	Open sea	-0.01977	0.0024	5.1e-17	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.0677388	0.00823761	2.147869e-16	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.002	None	3e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0666267	0.00823823	6.563652e-16	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.0653596	0.00823892	0.000000000000002292287	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.0690909	0.00881596	0.000000000000004929293	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.0686242	0.00890677	0.00000000000001395036	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.0631264	0.0082401	0.00000000000001961876	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg06880857	chr14:95591795	14	95591795	DICER1	Open sea	0.15183	0.0201	0.0000000000000414	-	25650246_gestational_age
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	0.055	0.00649	0.00000000000024	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.0600581	0.00824167	0.000000000000332767	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	0.01	0.0014	0.00000000000045	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.0592369	0.00824207	0.0000000000006935314	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	-	-	0.00000000000191	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	-0.0569556	0.00824317	0.000000000005066474	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0566185	0.00824333	0.000000000006753448	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	0.0005	0.000072	0.0000000000078	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23488578	chr14:95585023	14	95585023	DICER1	Open sea	0.02459	0.0034	0.000000000011	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.0535113	0.00824474	0.00000000008838572	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg06880857	chr14:95591795	14	95591795	DICER1	Open sea	-0.01198	0.0019	0.000000000201	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	0.0523871	0.00824523	0.0000000002165092	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg23488578	chr14:95585023	14	95585023	DICER1	Open sea	0.027	0.00387	0.00000000034	None	32795589_Kyung-WK_eosinophilia_discovery
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.021	0.00299	0.00000000035	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	0.0515198	0.00824561	0.0000000004268038	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	-	-	0.000000000592	-	26857698_primary_sjogrens_syndrome_whole_blood
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	-0.04206	0.0068	0.000000000722	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.0508263	0.0082459	0.0000000007286342	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	-0.78528254	0.1284	0.00000000097	-	25888029_ageing
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.0503939	0.00824608	0.000000001013504	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.0503583	0.0082461	0.000000001041327	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Cardenas A	Project Viva	31300640	Jul 12, 2019	fractional exhaled nitric oxide (FeNO)	EFO_0005536	None	Supplementary Data 2	DNA methylation	fractional exhaled nitric oxide (FeNO)	Age, Sex, Smoking, Cell composition (reference free), Batch effects, Ancestry (other), Body mass index, Education, sine and cosine of season at sample collection	Beta values	ppb	Illumina HumanMethylationEPIC	nasal epithelium	None	517	1	Children	Both	Other	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-4.2	0.682	0.0000000015	SE manually calculated	31300640_Cardenas-A_fractional_exhaled_nitric_oxide__feno_
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01049870	chr14:95601239	14	95601239	DICER1	Open sea	-0.0006	0.0001	0.0000000016	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.0486304	0.0082468	0.000000003785936	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0502462	0.00855551	0.000000004373492	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18503758	chr14:95564636	14	95564636	DICER1	Open sea	-0.0011	0.00019	0.0000000051	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0519918	0.00889431	0.000000005157285	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	ch.14.1558261F	chr14:95593869	14	95593869	DICER1	Open sea	0.01538	0.0026	0.00000000574	-	23334450_rheumatoid_arthritis
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg18503758	chr14:95564636	14	95564636	DICER1	Open sea	-0.02038	0.0035	0.0000000062	-	23334450_rheumatoid_arthritis
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg03397819	chr14:95612979	14	95612979	DICER1	Open sea	0.022	0.00358	0.000000013	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.049343	0.00868297	0.00000001350783	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg10937777	chr14:95603150	14	95603150	DICER1	Open sea	-0.02	0.00325	0.000000018	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.0462193	0.00824775	0.00000002133965	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0498427	0.00889943	0.00000002173624	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0452451	0.00824812	0.00000004191121	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	-0.0444029	0.00824843	0.00000007430323	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Shah S	-	25249537	2014-09-23	Sex	PATO_0000047	Discovery	Table S3	DNA methylation	Sex	Smoking, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	815	1	70	Both	European	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	-	-	0.0000000772	-	25249537_sex_discovery
Shah S	-	25249537	2014-09-23	Sex	PATO_0000047	Replication	Table S3	DNA methylation	Sex	Smoking, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	445	1	79	Both	European	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	-	-	0.0000000848	-	25249537_sex_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	0.0439182	0.0082486	0.0000001028265	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.0436946	0.00824869	0.0000001193146	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10948630	chr14:95562368	14	95562368	DICER1	Open sea	0.0041	None	0.00000012	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01049870	chr14:95601239	14	95601239	DICER1	Open sea	-0.01328	0.00243	0.00000014	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	0.0433508	0.00824881	0.0000001497689	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	-0.0035	0.00063	0.00000016	None	33564054_Kashima-K_gestational_age
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	-0.423033	0.0809	0.000000172	None	27105112_hiv_infection_cd4_tcells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23899649	chr14:95553486	14	95553486	DICER1	Open sea	-0.001	0.0002	0.00000022	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23899649	chr14:95553486	14	95553486	DICER1	Open sea	0.0012	None	0.00000025	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	ch.14.1558261F	chr14:95593869	14	95593869	DICER1	Open sea	-1.03741	0.2013	0.000000256	-	27105112_hiv_infection_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	MMP10 protein levels (SeqId = 8479-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MMP10 protein levels (SeqId = 8479-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Stromelysin-2	774	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.98	0.191	0.00000029	None	Gadd-DA_mmp10_protein_levels__seqid___8479-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	-0.0422737	0.00824919	0.0000003019744	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0419589	0.0082493	0.0000003695159	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0419542	0.0082493	0.0000003706294	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0419533	0.0082493	0.0000003708351	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0448338	0.00890131	0.0000004790922	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	-0.0413668	0.0082495	0.0000005380355	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0445236	0.00890271	0.0000005765341	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0411427	0.00824958	0.000000619449	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	0.0411279	0.00824959	0.0000006252139	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.0407555	0.00824971	0.0000007888788	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0406417	0.00824975	0.0000008466448	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	ch.14.1558261F	chr14:95593869	14	95593869	DICER1	Open sea	0.00054	0.00011	0.00000087	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Xu C-J	MeDALL	29496485	2018-02-26	Asthma	EFO_0000270	Discovery adjusted for cell composition excluding eosinophils at age 8	Table 1	DNA methylation	Asthma	Sex, batch effects, cell composition (reference based)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	731	2	Children	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	None	None	0.000001	None	29496485_Xu-C-J_asthma_discovery_adjusted_for_cell_composition_excluding_eosinophils_at_age_8
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.039823	0.00825002	0.000001399916	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.0397761	0.00825004	0.000001440385	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23899649	chr14:95553486	14	95553486	DICER1	Open sea	0.0041	None	0.0000015	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	-0.0396966	0.00825006	0.000001511596	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	0.0396196	0.00825009	0.000001583811	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.0652968	0.0139345	0.000002811249	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.0416282	0.00888895	0.000002850429	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.0414347	0.00887097	0.000003026616	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	0.0384849	0.00825045	0.000003119847	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	KIT protein levels (SeqId = 2475-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIT protein levels (SeqId = 2475-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mast/stem cell growth factor receptor Kit	774	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.89	0.192	0.0000036	None	Gadd-DA_kit_protein_levels__seqid___2475-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.0381922	0.00825055	0.000003704999	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.038131	0.00825057	0.000003840057	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0409048	0.00887463	0.000004076572	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0410525	0.0089094	0.00000410437	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	0.0379963	0.00825061	0.000004153908	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PRG2 protein levels (SeqId = 7258-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRG2 protein levels (SeqId = 7258-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bone marrow proteoglycan	774	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-0.88	0.192	0.0000042	None	Gadd-DA_prg2_protein_levels__seqid___7258-5__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24158307	chr14:95599667	14	95599667	DICER1	Open sea	0.0031	0.00067	0.0000043	None	33450751_Mulder-RH_sex_discovery
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	-	-	0.00000475	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	-0.0376323	0.00825072	0.000005130047	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.0376055	0.00825073	0.000005210066	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CLSTN2 protein levels (SeqId = 18882-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLSTN2 protein levels (SeqId = 18882-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calsyntenin-2	774	1	Adults (18-65 years)	Both	European	cg24003268	chr14:95569941	14	95569941	DICER1	Open sea	0.75	0.165	0.0000053	None	Gadd-DA_clstn2_protein_levels__seqid___18882-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0405321	0.00892701	0.000005659643	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Reese SE	PACE	30579849	2018-12-21	Asthma	EFO_0000270	Meta-analysis with DNAm measured in children	Table 2	Asthma	DNA methylation	Batch effects, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	2862	9	Children	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	-9.3	2	0.0000059	None	30579849_Reese-SE_asthma_meta-analysis_with_dnam_measured_in_children
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	0.0373007	0.00825083	0.000006207482	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0428129	0.00950068	0.00000664796	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0399288	0.00888828	0.000007099851	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	0.0369458	0.00825093	0.000007599385	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0494443	0.0110434	0.000007617196	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.0402351	0.00906821	0.000009191259	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0364235	0.00825109	0.0000102022	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	-0.0363456	0.00825112	0.00001065684	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	0.00081021	0.00018317	0.0000107	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	0.0361074	0.00825119	0.00001216973	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0061	0.0014	0.000013	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04112704	chr14:95608514	14	95608514	DICER1	Open sea	0.0359664	0.00825123	0.00001316026	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.0377308	0.0087182	0.00001515925	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04112704	chr14:95608514	14	95608514	DICER1	Open sea	-0.0353375	0.00825141	0.00001859003	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.0386232	0.00906297	0.00002041871	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04112704	chr14:95608514	14	95608514	DICER1	Open sea	0.0012	None	0.000021	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	-0.0347342	0.00825159	0.0000257586	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SCUBE1 protein levels (SeqId = 8989-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SCUBE1 protein levels (SeqId = 8989-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal peptide, CUB and EGF-like domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	0.76	0.18	0.000026	None	Gadd-DA_scube1_protein_levels__seqid___8989-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXDC1 protein levels (SeqId = 9235-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXDC1 protein levels (SeqId = 9235-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg06501267	chr14:95577676	14	95577676	DICER1	Open sea	-0.682	0.162	0.000026	None	Gadd-DA_plxdc1_protein_levels__seqid___9235-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06501267	chr14:95577676	14	95577676	DICER1	Open sea	-0.0346995	0.0082516	0.00002624137	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.0346638	0.00825161	0.0000267489	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.0363523	0.00866117	0.00002718753	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.014	0.0035	0.000029	None	33450751_Mulder-RH_sex_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10937777	chr14:95603150	14	95603150	DICER1	Open sea	0.166753	0.0398867	0.00002920847	None	39706196_Hannah-M.-Smith_bmi_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKAA2 protein levels (SeqId = 5245-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKAA2 protein levels (SeqId = 5245-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 5'-AMP-activated protein kinase subunit beta-2|5'-AMP-activated protein kinase catalytic subunit alpha-2|5'-AMP-activated protein kinase subunit gamma-1	774	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.97	0.232	0.00003	None	Gadd-DA_prkaa2_protein_levels__seqid___5245-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBASH3B protein levels (SeqId = 12558-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBASH3B protein levels (SeqId = 12558-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-associated and SH3 domain-containing protein B	774	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.96	0.232	0.000033	None	Gadd-DA_ubash3b_protein_levels__seqid___12558-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.0342213	0.00825174	0.00003385205	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	0.0341935	0.00825174	0.00003435302	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0629599	0.0152404	0.00003630219	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18503758	chr14:95564636	14	95564636	DICER1	Open sea	0.101099	0.0244743	0.00003631414	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0388132	0.00950407	0.00004453115	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0336822	0.00825189	0.00004493381	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04112704	chr14:95608514	14	95608514	DICER1	Open sea	0.0336817	0.00825189	0.00004494552	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Witt S	None	32080920	02-02-2020	alcohol withdrawal recovery	None	discovery	Table S1	DNA methylation	alcohol withdrawal recovery	Age, Smoking, Cell composition (reference based), Batch effects	Beta values	None	Illumina HumanMethylationEPIC	whole blood	two weeks after vs active withdrawal	99	1	Adults	Males	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	1	0.234	0.000045	None	32080920_Witt-S_alcohol_withdrawal_recovery_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	BNIP3 protein levels (SeqId = 7045-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BNIP3 protein levels (SeqId = 7045-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3	774	1	Adults (18-65 years)	Both	European	cg01049870	chr14:95601239	14	95601239	DICER1	Open sea	-1.18	0.29	0.000046	None	Gadd-DA_bnip3_protein_levels__seqid___7045-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	0.033591	0.00825191	0.00004711883	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05616072	chr14:95593446	14	95593446	DICER1	Open sea	0.0335113	0.00825193	0.00004911271	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	0.0334582	0.00825195	0.00005048253	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	VIM protein levels (SeqId = 15540-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VIM protein levels (SeqId = 15540-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vimentin	774	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.94	0.233	0.000052	None	Gadd-DA_vim_protein_levels__seqid___15540-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.0365138	0.00904755	0.00005470168	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0332721	0.008252	0.00005558238	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Xu C-J	MeDALL	29496485	2018-02-26	Asthma	EFO_0000270	Discovery adjusted for cell composition including eosinophils at age 8	Table 1	DNA methylation	Asthma	Sex, batch effects, cell composition (reference based)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	731	2	Children	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	None	None	0.000056	None	29496485_Xu-C-J_asthma_discovery_adjusted_for_cell_composition_including_eosinophils_at_age_8
Gadd DA	Generation Scotland	35945220	31/07/2022	SERPING1 protein levels (SeqId = 4479-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SERPING1 protein levels (SeqId = 4479-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plasma protease C1 inhibitor	774	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.66	0.164	0.000056	None	Gadd-DA_serping1_protein_levels__seqid___4479-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LTB4R protein levels (SeqId = 13477-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LTB4R protein levels (SeqId = 13477-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leukotriene B4 receptor 1	774	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.934	0.232	0.000057	None	Gadd-DA_ltb4r_protein_levels__seqid___13477-65__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ASMTL protein levels (SeqId = 10089-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASMTL protein levels (SeqId = 10089-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein	774	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.94	0.233	0.000058	None	Gadd-DA_asmtl_protein_levels__seqid___10089-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.035797	0.00890161	0.00005814216	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.0358076	0.00891519	0.00005937203	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.0331256	0.00825204	0.00005993779	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	DTX3L protein levels (SeqId = 11643-73)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DTX3L protein levels (SeqId = 11643-73)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase DTX3L	774	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.93	0.233	0.000065	None	Gadd-DA_dtx3l_protein_levels__seqid___11643-73__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg04112704	chr14:95608514	14	95608514	DICER1	Open sea	-0.89932	0.2257	0.0000678	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12170933	chr14:95620298	14	95620298	DICER1	North shelf	0.0361532	0.00907476	0.0000681115	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CSF2 protein levels (SeqId = 4697-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSF2 protein levels (SeqId = 4697-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granulocyte-macrophage colony-stimulating factor	774	1	Adults (18-65 years)	Both	European	cg10908574	chr14:95574405	14	95574405	DICER1	Open sea	0.43	0.109	0.000069	None	Gadd-DA_csf2_protein_levels__seqid___4697-59__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	-0.032823	0.00825212	0.00006997	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FAF2 protein levels (SeqId = 9738-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAF2 protein levels (SeqId = 9738-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: FAS-associated factor 2	774	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.92	0.232	0.00007	None	Gadd-DA_faf2_protein_levels__seqid___9738-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBB protein levels (SeqId = 6641-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBB protein levels (SeqId = 6641-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Polyubiquitin-B	774	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.65	0.164	0.000071	None	Gadd-DA_ubb_protein_levels__seqid___6641-60__somascan_protein_measurement
Joubert BR	PACE	27040690	2016-04-07	Maternal smoking in pregnancy	EFO_0006527, EFO_0005671, EFO_0004318, EFO_0002950	Sustained maternal smoking in pregnancy effect on newborns	Table S3	DNA methylation	Maternal smoking in pregnancy	Maternal age, maternal education, parity and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	5647	9	0	Missing	European,African,Admixed,Other	cg24130561	chr14:95621734	14	95621734	DICER1	North shore	-0.012	0.003	0.0000749	-	27040690_maternal_smoking_in_pregnancy_sustained_maternal_smoking_in_pregnancy_effect_on_newborns
Gadd DA	Generation Scotland	35945220	31/07/2022	DERL1 protein levels (SeqId = 13393-46)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DERL1 protein levels (SeqId = 13393-46)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Derlin-1	774	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.91	0.231	0.000077	None	Gadd-DA_derl1_protein_levels__seqid___13393-46__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01901579	chr14:95615731	14	95615731	DICER1	Open sea	0.00082	0.00021	0.000078	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09380122	chr14:95565486	14	95565486	DICER1	Open sea	-0.0431447	0.0109223	0.00007846983	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18503758	chr14:95564636	14	95564636	DICER1	Open sea	0.0011	None	0.000079	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	-0.0324113	0.00825223	0.00008619699	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	-0.0324017	0.00825224	0.00008661732	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18875895	chr14:95610751	14	95610751	DICER1	Open sea	0.0323353	0.00825225	0.00008955981	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.0322069	0.00825229	0.00009551828	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25594260	chr14:95600774	14	95600774	DICER1	Open sea	0.0321719	0.0082523	0.00009720419	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PDE5A protein levels (SeqId = 16805-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDE5A protein levels (SeqId = 16805-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: cGMP-specific 3',5'-cyclic phosphodiesterase	774	1	Adults (18-65 years)	Both	European	cg14237266	chr14:95604229	14	95604229	DICER1	Open sea	-0.91	0.233	0.000098	None	Gadd-DA_pde5a_protein_levels__seqid___16805-5__somascan_protein_measurement