author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	-0.0014	0.00015	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01410440	chr7:157193063	7	157193063	DNAJB6	Island	-0.0053	0.0003	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0014	0.00013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02994253	chr7:157209799	7	157209799	DNAJB6	North shore	-0.0036	0.0002	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03996020	chr7:157180124	7	157180124	DNAJB6	Open sea	0.0032	0.00032	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05090392	chr7:157209531	7	157209531	DNAJB6	South shore	-0.0072	0.00032	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	0.002	0.0002	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.013	0.0013	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0056	0.00027	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07569018	chr7:157202818	7	157202818	DNAJB6	Island	-0.00022	0.000023	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0036	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0034	0.00017	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0027	0.00021	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.014	0.0013	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11057877	chr7:157201503	7	157201503	DNAJB6	North shore	-0.0012	0.00012	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11695266	chr7:157129166	7	157129166	DNAJB6	Island	0.00055	0.000055	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13858484	chr7:157162202	7	157162202	DNAJB6	Open sea	-0.0012	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17255085	chr7:157193359	7	157193359	DNAJB6	South shore	-0.0022	0.00018	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0021	0.00018	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.018	0.0012	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0056	0.00022	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18327321	chr7:157193101	7	157193101	DNAJB6	Island	-0.0028	0.00032	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0034	0.00016	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0035	0.00026	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19858151	chr7:157200669	7	157200669	DNAJB6	North shore	-0.0016	0.00017	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20603964	chr7:157195543	7	157195543	DNAJB6	South shelf	-0.00061	0.000064	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20723414	chr7:157207071	7	157207071	DNAJB6	Island	-0.00041	0.000043	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22412150	chr7:157208980	7	157208980	DNAJB6	Island	-0.0007	0.00006	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22939563	chr7:157162115	7	157162115	DNAJB6	Open sea	-0.0029	0.00035	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	0.0013	0.000095	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25024001	chr7:157207074	7	157207074	DNAJB6	Island	-0.00034	0.000037	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25134890	chr7:157200205	7	157200205	DNAJB6	North shelf	-0.0015	0.00018	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0037	0.00031	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.00074	0.000088	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27496299	chr7:157171202	7	157171202	DNAJB6	Open sea	-0.0021	0.0002	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.45323	0.00534	1e-154	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23768894	chr7:157140029	7	157140029	DNAJB6	Open sea	0.63818	0.00753	1.2e-154	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.48025	0.0068	7.5e-140	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0024	None	2.1e-128	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg06229455	chr7:157189721	7	157189721	DNAJB6	North shelf	0.22734	0.00398	7.200000000000001e-123	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22412150	chr7:157208980	7	157208980	DNAJB6	Island	0.00078	None	1.5e-88	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.13215	0.00407	4.4e-80	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg03836195	chr7:157205668	7	157205668	DNAJB6	North shore	0.14911	0.00465	3.1e-79	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12910268	chr7:157185351	7	157185351	DNAJB6	Open sea	0.11445	0.00383	2.5e-74	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	ch.7.3356624R	chr7:157205374	7	157205374	DNAJB6	North shore	-	-	1.43e-72	-	23526956_clear_cell_renal_carcinoma
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0021	None	3.7e-72	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	-0.10365	0.0036	7.9e-72	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.21528	0.00754	3.4e-71	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.145162	0.00816912	6.553618e-70	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg17833937	chr7:157142583	7	157142583	DNAJB6	Open sea	0.09927	0.00412	4.7000000000000005e-60	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.133202	0.008183	4.66061e-59	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.13339	0.00596	1.4999999999999999e-55	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-	-	6.819999999999999e-54	-	28056824_age_4_vs_age_0
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg11695266	chr7:157129166	7	157129166	DNAJB6	Island	-0.04487	0.00209	5.2e-53	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.125152	0.00819165	2.707278e-52	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26160086	chr7:157205545	7	157205545	DNAJB6	North shore	0.05641	0.00271	2.8e-51	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07186946	chr7:157195668	7	157195668	DNAJB6	South shelf	0.06398	0.00334	1.8e-46	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20245520	chr7:157185279	7	157185279	DNAJB6	Open sea	0.03672	0.00195	1.9e-45	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.115293	0.00820151	1.349603e-44	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02994253	chr7:157209799	7	157209799	DNAJB6	North shore	0.05854	0.0032	4.6e-44	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24185680	chr7:157171288	7	157171288	DNAJB6	Open sea	0.05723	0.00315	1.1999999999999999e-43	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.08638	0.00504	1.1e-40	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.109853	0.0082066	1.264961e-40	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01766193	chr7:157202248	7	157202248	DNAJB6	North shore	0.05946	0.0035	3.1e-40	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg15248935	chr7:157180055	7	157180055	DNAJB6	Open sea	-1.98063	0.083	6.03e-40	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg20245520	chr7:157185279	7	157185279	DNAJB6	Open sea	3.05527	0.12899	1.06e-39	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.108323	0.00820799	1.528922e-39	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	0.08467	0.00526	1.7e-37	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg26668151	chr7:157180005	7	157180005	DNAJB6	Open sea	-2.13498	0.10509	8.83e-35	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-2.60908	0.12856	9.53e-35	-	25282492_fetal_vs_adult_liver
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg09710771	chr7:157199809	7	157199809	DNAJB6	North shelf	0.04416	0.00295	4.1e-34	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0996997	0.00821543	9.917729e-34	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0990229	0.00821599	2.704169e-33	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11695266	chr7:157129166	7	157129166	DNAJB6	Island	0.00055	None	3e-33	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg03996020	chr7:157180124	7	157180124	DNAJB6	Open sea	-	-	3.09e-33	-	28056824_age_4_vs_age_0
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22412150	chr7:157208980	7	157208980	DNAJB6	Island	0.0024	None	9.999999999999999e-33	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0979494	0.00821687	1.308645e-32	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0977697	0.00821701	1.701031e-32	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0977177	0.00821706	1.835008e-32	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20603964	chr7:157195543	7	157195543	DNAJB6	South shelf	0.03666	0.00256	4.1000000000000003e-32	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0958495	0.00821856	2.7208860000000003e-31	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.126681	0.0109162	5.322385000000001e-31	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0947966	0.00821939	1.215256e-30	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0942071	0.00821985	2.788937e-30	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06416110	chr7:157190100	7	157190100	DNAJB6	North shelf	0.0011	None	1.2e-29	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-	-	1.3e-29	-	28056824_age_4_vs_age_0
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.092509	0.00822117	2.965092e-29	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0922153	0.00822139	4.443293e-29	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	ch.7.3356624R	chr7:157205374	7	157205374	DNAJB6	North shore	0.00075	None	7.4e-29	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0912561	0.00822212	1.650128e-28	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.02944	0.00226	3e-28	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0904543	0.00822272	4.889102000000001e-28	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13858484	chr7:157162202	7	157162202	DNAJB6	Open sea	0.0013	None	1e-27	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.105258	0.00968185	2.001895e-27	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0888901	0.00822389	3.958589e-27	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.088804	0.00822395	4.436895e-27	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0887677	0.00822398	4.6551630000000006e-27	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13858484	chr7:157162202	7	157162202	DNAJB6	Open sea	0.03808	0.00306	1.6e-26	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10665071	chr7:157198699	7	157198699	DNAJB6	North shelf	0.13807	0.01113	2.2e-26	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0874631	0.00822493	2.584075e-26	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08010530	chr7:157200028	7	157200028	DNAJB6	North shelf	0.0013	None	2.7e-26	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0873852	0.00822499	2.86031e-26	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	-0.0868098	0.0082254	6.038865999999999e-26	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-	-	1.27e-25	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0862076	0.00822583	1.313157e-25	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	0.00095	None	1.9999999999999998e-25	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03559568	chr7:157208968	7	157208968	DNAJB6	Island	0.0015	None	2.4e-25	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	0.03239	0.0027	4.2e-25	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17255085	chr7:157193359	7	157193359	DNAJB6	South shore	0.0016	None	4.2e-25	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13515783	chr7:157201622	7	157201622	DNAJB6	North shore	0.02526	0.00213	9.9e-25	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.112654	0.0109773	1.2599389999999999e-24	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	-0.0835683	0.00822769	3.708962e-24	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.111226	0.0109889	5.308268e-24	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18753341	chr7:157202405	7	157202405	DNAJB6	Island	0.00888	0.00077	8.3e-24	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.355118	0.0352566	8.51382e-24	None	39706196_Hannah-M.-Smith_bmi_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.24024	0.0239229	1.1538960000000001e-23	None	39706196_Hannah-M.-Smith_bmi_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.491589	0.0489664	1.1885740000000001e-23	None	39706196_Hannah-M.-Smith_bmi_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	ch.7.3356624R	chr7:157205374	7	157205374	DNAJB6	North shore	0.02033	0.00178	2.1e-23	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0820043	0.00822876	2.5576290000000002e-23	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0809441	0.00822948	9.27591e-23	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0809282	0.00822949	9.456430000000001e-23	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0807143	0.00822963	1.223705e-22	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0800739	0.00823006	2.637479e-22	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0800612	0.00823007	2.677732e-22	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0798722	0.00823019	3.355177e-22	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0797268	0.00823029	3.989131e-22	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	0.0794846	0.00823045	5.31854e-22	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0790536	0.00823073	8.853358000000001e-22	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.078875	0.00823085	1.092703e-21	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg22412150	chr7:157208980	7	157208980	DNAJB6	Island	0.03888	0.00364	3.1e-21	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.81637198	0.0874	9.770000000000001e-21	-	25888029_ageing
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-2.5	0.264	2.1e-20	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0903024	0.00976945	2.712293e-20	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0760041	0.00823269	3.013827e-20	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Nones K	-	24500968	2014-05-09	Pancreatic ductal adenocarcinoma	EFO_0002517	-	Table S4	DNA methylation	Pancreatic ductal adenocarcinoma	-	Beta values	-	Illumina HumanMethylation450	Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata	-	196	1	-	Missing	None	cg15248935	chr7:157180055	7	157180055	DNAJB6	Open sea	-	-	3.86e-20	-	24500968_pancreatic_ductal_adenocarcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.0755112	0.008233	5.2618669999999995e-20	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0753172	0.00823312	6.545672e-20	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0811343	0.00898649	1.954134e-19	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0802676	0.00889381	2.014947e-19	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12910268	chr7:157185351	7	157185351	DNAJB6	Open sea	0.0015	None	2.2e-19	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0739522	0.00823396	2.9949279999999997e-19	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-2	0.222	3.7e-19	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0737187	0.00823411	3.8740239999999996e-19	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0796186	0.00891603	4.766343e-19	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Hannon E	None	33646943	2021-02-26	schizophrenia	EFO_0000692	fixed effects meta-analysis	Supplementary Table 3	DNA methylation	schizophrenia	Age, sex, batch effects, cell composition (reference based), smoking	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	3264	7	Adults	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	1.03	0.117	1e-18	None	33646943_Hannon-E_schizophrenia_fixed_effects_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0720762	0.0082351	2.3151850000000002e-18	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21010435	chr7:157208882	7	157208882	DNAJB6	Island	0.00645	0.00067	3.2e-18	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0714267	0.00823548	4.643576e-18	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.0713027	0.00823556	5.2996100000000004e-18	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0955844	0.0110695	6.473022e-18	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-1.3	0.147	6.7e-18	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0709412	0.00823577	7.780586e-18	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0708874	0.0082358	8.236497e-18	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0705478	0.008236	1.1791020000000001e-17	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.070446	0.00823606	1.3125690000000001e-17	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08010530	chr7:157200028	7	157200028	DNAJB6	North shelf	0.01786	0.0019	1.6e-17	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg03996020	chr7:157180124	7	157180124	DNAJB6	Open sea	0.06897	0.00739	2.5e-17	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.212829	0.0251612	2.919174e-17	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	-0.0696339	0.00823653	3.0702230000000004e-17	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0693682	0.00823668	4.045719e-17	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0689826	0.0082369	6.027207e-17	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0917691	0.0109768	6.815988e-17	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3034027 (gene symbol: DNAJB6)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3034027 (gene symbol: DNAJB6)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg22939563	chr7:157162115	7	157162115	DNAJB6	Open sea	None	None	7.9e-17	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3034027__gene_symbol__dnajb6__meta-analysis
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.405711	0.0489736	1.274228e-16	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0681001	0.0082374	1.48845e-16	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0680534	0.00823743	1.560781e-16	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.034	0.00407	1.9e-16	None	Robert-F-Hillary_Incident_COPD_Basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.192037	0.023384	2.321106e-16	None	39706196_Hannah-M.-Smith_bmi_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	0.0011	None	2.7e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0055	None	3.2e-16	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0672088	0.0082379	3.665937e-16	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03937368	chr7:157203490	7	157203490	DNAJB6	North shore	0.0015	None	4.6e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0668706	0.00823809	5.145526e-16	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0668251	0.00823812	5.385057e-16	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0666938	0.00823819	6.138948e-16	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07186946	chr7:157195668	7	157195668	DNAJB6	South shelf	-0.0018	0.00022	6.7e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	-0.0017	0.00021	6.7e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	-0.0664295	0.00823833	7.986388e-16	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0690259	0.00857437	8.893391e-16	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0014	0.00017	8.9e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27496299	chr7:157171202	7	157171202	DNAJB6	Open sea	0.0016	None	9.7e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0661458	0.00823849	0.000000000000001058002	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05090392	chr7:157209531	7	157209531	DNAJB6	South shore	-0.016	0.002	0.0000000000000011	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0680529	0.00856041	0.000000000000002004857	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.190484	0.0240038	0.000000000000002222254	None	39706196_Hannah-M.-Smith_body_fat_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25134890	chr7:157200205	7	157200205	DNAJB6	North shelf	0.0014	None	0.0000000000000024	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	-0.0652574	0.00823897	0.000000000000002533022	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Witt S	None	32080920	02-02-2020	alcohol withdrawal recovery	None	discovery	Table S1	DNA methylation	alcohol withdrawal recovery	Age, Smoking, Cell composition (reference based), Batch effects	Beta values	None	Illumina HumanMethylationEPIC	whole blood	two weeks after vs active withdrawal	99	1	Adults	Males	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	4.1	0.436	0.0000000000000026	None	32080920_Witt-S_alcohol_withdrawal_recovery_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0651873	0.00823901	0.000000000000002712344	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0766044	0.00968806	0.000000000000002821629	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0710003	0.00899075	0.000000000000003057766	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.185073	0.023441	0.000000000000003070004	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0646415	0.0082393	0.000000000000004608294	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	-0.0645409	0.00823936	0.000000000000005078853	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18327321	chr7:157193101	7	157193101	DNAJB6	Island	0.0025	None	0.0000000000000052	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.182931	0.02337	0.000000000000005258349	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.198066	0.025332	0.000000000000005637602	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	0.0087	0.0011	0.0000000000000067	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg23768894	chr7:157140029	7	157140029	DNAJB6	Open sea	-0.22117	0.0284	0.00000000000000734	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0641427	0.00823957	0.000000000000007452569	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg19249678	chr7:157129666	7	157129666	DNAJB6	Island	0.00727	9e-04	0.00000000000000782	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0640776	0.0082396	0.00000000000000793228	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-2.5	0.319	0.0000000000000095	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.19436	0.0252413	0.00000000000001432955	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0632762	0.00824003	0.0000000000000170271	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.27114	0.0353808	0.00000000000001905412	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	-0.0630786	0.00824013	0.00000000000002052529	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24815507	chr7:157198482	7	157198482	DNAJB6	North shelf	-0.0009	0.00012	0.000000000000024	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0628658	0.00824024	0.00000000000002508651	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.186709	0.0244884	0.00000000000002572679	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0627073	0.00824032	0.00000000000002911677	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0625871	0.00824038	0.00000000000003259182	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0624738	0.00824044	0.0000000000000362387	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0623547	0.0082405	0.00000000000004050595	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.0623208	0.00824052	0.00000000000004181051	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.90890418	0.1209	0.0000000000000549	-	25888029_ageing
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0617221	0.00824083	0.00000000000007290963	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26860459	chr7:157199417	7	157199417	DNAJB6	North shelf	0.00098	None	0.000000000000073	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0615865	0.0082409	0.00000000000008264033	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0615666	0.00824091	0.00000000000008416813	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0615142	0.00824094	0.00000000000008833855	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0613973	0.00824099	0.00000000000009836947	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06229455	chr7:157189721	7	157189721	DNAJB6	North shelf	0.0019	None	0.0000000000001	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.167962	0.0226625	0.0000000000001303896	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg07186946	chr7:157195668	7	157195668	DNAJB6	South shelf	-2.680647	0.3644	0.000000000000189	-	27105112_hiv_infection_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.277506	0.0378976	0.0000000000002540326	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0602374	0.00824158	0.0000000000002831016	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg00553120	chr7:157129669	7	157129669	DNAJB6	Island	0.00608	8e-04	0.000000000000321	-	23334450_rheumatoid_arthritis
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.357499	0.0491462	0.0000000000003634146	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0599583	0.00824172	0.0000000000003640348	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0599153	0.00824174	0.0000000000003783689	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0598455	0.00824177	0.0000000000004028341	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13858484	chr7:157162202	7	157162202	DNAJB6	Open sea	0.0042	None	0.00000000000045	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.01	0.00121	0.00000000000052	None	32795589_Kyung-WK_eosinophilia_discovery
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	7.54e-05	1.05e-05	0.000000000000604	-	27843151_alcohol_consumption_per_day_african_ancestry
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.00638	0.00089	0.00000000000077	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0963987	0.0134613	0.0000000000008381089	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0590158	0.00824218	0.000000000000843805	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0589915	0.00824219	0.0000000000008621416	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0589841	0.0082422	0.0000000000008677521	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.0588958	0.00824224	0.0000000000009381865	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.078006	0.010954	0.000000000001119196	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0586942	0.00824234	0.000000000001120758	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.058485	0.00824244	0.000000000001346971	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0583504	0.0082425	0.000000000001515682	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0771373	0.0109013	0.000000000001551407	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0582483	0.00824255	0.000000000001657151	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0582401	0.00824256	0.00000000000166917	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17255085	chr7:157193359	7	157193359	DNAJB6	South shore	0.0051	None	0.0000000000023	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18753341	chr7:157202405	7	157202405	DNAJB6	Island	-0.00017	0.000025	0.0000000000023	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.266174	0.0379893	0.000000000002532757	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0697596	0.00996361	0.000000000002643632	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0576798	0.00824283	0.000000000002717252	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.167381	0.0239401	0.000000000002815206	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.042	0.00606	0.0000000000031	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0794637	0.0113905	0.0000000000031601	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03559568	chr7:157208968	7	157208968	DNAJB6	Island	0.0047	None	0.0000000000033	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03836195	chr7:157205668	7	157205668	DNAJB6	North shore	0.0011	None	0.0000000000033	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0672482	0.00966623	0.000000000003622434	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	0.012	0.0018	0.0000000000045	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0669918	0.00968749	0.000000000004862129	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0569916	0.00824315	0.000000000004913029	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	0.0569356	0.00824318	0.000000000005153793	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg26860459	chr7:157199417	7	157199417	DNAJB6	North shelf	0.18409	0.0267	0.00000000000522	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0568934	0.0082432	0.000000000005342983	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0568846	0.0082432	0.000000000005383291	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.056865	0.00824321	0.000000000005474376	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0567956	0.00824324	0.000000000005808042	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0565743	0.00824335	0.000000000007012045	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03836195	chr7:157205668	7	157205668	DNAJB6	North shore	-0.00097	0.00014	0.0000000000071	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0565546	0.00824336	0.000000000007130381	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-	-	0.00000000000753	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0748161	0.0109202	0.000000000007616226	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0564736	0.00824339	0.000000000007637889	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0564137	0.00824342	0.000000000008035975	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08010530	chr7:157200028	7	157200028	DNAJB6	North shelf	0.004	None	0.0000000000087	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0603241	0.00889104	0.00000000001206863	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.239217	0.0352855	0.00000000001245175	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.055848	0.00824369	0.00000000001294681	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10665071	chr7:157198699	7	157198699	DNAJB6	North shelf	0.0021	None	0.000000000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.17671	0.0262	0.0000000000144	-	25650246_gestational_age
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26668151	chr7:157180005	7	157180005	DNAJB6	Open sea	0.00086	0.00013	0.000000000015	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0555876	0.00824381	0.0000000000161004	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	0.0555026	0.00824384	0.00000000001728337	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09903872	chr7:157129451	7	157129451	DNAJB6	Island	0.00042	0.000062	0.000000000018	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0734536	0.0109358	0.00000000001925839	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.16673	0.0248	0.0000000000194	-	25650246_gestational_age
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-	-	0.0000000000212	-	26857698_primary_sjogrens_syndrome_whole_blood
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01410440	chr7:157193063	7	157193063	DNAJB6	Island	0.0022	None	0.000000000022	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0551132	0.00824402	0.00000000002388769	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0550776	0.00824404	0.00000000002460432	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0597719	0.00895977	0.00000000002629189	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0645351	0.00969145	0.00000000002855485	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0728861	0.0109536	0.0000000000295185	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25039694	chr7:157192974	7	157192974	DNAJB6	Island	-0.0024	0.00036	0.000000000032	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.0547534	0.00824419	0.00000000003215329	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0546389	0.00824424	0.00000000003532797	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0544954	0.0082443	0.00000000003974091	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0544575	0.00824432	0.00000000004099236	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0542964	0.00824439	0.000000000046766	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0542383	0.00824442	0.00000000004903769	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0541565	0.00824445	0.00000000005241552	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0584836	0.0089238	0.00000000005801558	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0864738	0.0132141	0.00000000006185287	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.225132	0.0344092	0.00000000006199114	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0539409	0.00824455	0.00000000006245632	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	0.053929	0.00824456	0.00000000006306098	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14651435	chr7:157209551	7	157209551	DNAJB6	South shore	0.0016	0.00024	0.00000000008	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg19428573	chr7:157200793	7	157200793	DNAJB6	North shore	-0.279827	0.0430399	0.00000000008155216	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0596163	0.00916833	0.00000000008159854	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0536039	0.0082447	0.00000000008202906	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Hannon E	-	27572077	2016-08-30	Schizophrenia	EFO_0000692	Phase 2	Table S3	DNA methylation	Schizophrenia	Age, sex, smoking, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	847	1	-	Missing	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.014079	0.002168	0.0000000000829	-	27572077_schizophrenia_phase_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0535229	0.00824474	0.00000000008756274	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	-0.0534705	0.00824476	0.00000000009133114	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0625506	0.00965024	0.00000000009355345	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0534292	0.00824478	0.00000000009441868	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg00553120	chr7:157129669	7	157129669	DNAJB6	Island	0.00272	0.0004	0.000000000098	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0019	None	0.0000000001	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg23768894	chr7:157140029	7	157140029	DNAJB6	Open sea	0.048	0.00668	0.0000000001	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0704588	0.0109072	0.0000000001081002	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0532593	0.00824485	0.0000000001082104	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	0.0530889	0.00824493	0.0000000001240265	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0530853	0.00824493	0.0000000001243798	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg04430780	chr7:157199439	7	157199439	DNAJB6	North shelf	0.21925	0.0342	0.000000000138	-	25650246_gestational_age
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15248935	chr7:157180055	7	157180055	DNAJB6	Open sea	0.01135	0.00167	0.00000000014	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.054	0.00836	0.00000000014	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0709049	0.0110473	0.0000000001420448	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0528965	0.00824501	0.0000000001445939	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.376991	0.0587892	0.0000000001467912	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.0528548	0.00824503	0.0000000001494742	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0528538	0.00824503	0.0000000001495946	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19249678	chr7:157129666	7	157129666	DNAJB6	Island	0.00268	0.0004	0.00000000015	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0528327	0.00824504	0.0000000001521228	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11695266	chr7:157129166	7	157129166	DNAJB6	Island	0.0016	None	0.00000000017	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0525092	0.00824518	0.000000000196607	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27496299	chr7:157171202	7	157171202	DNAJB6	Open sea	0.0051	None	0.0000000002	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	0.0021	None	0.00000000021	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-2.7	0.431	0.00000000021	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Nones K	-	24500968	2014-05-09	Pancreatic ductal adenocarcinoma	EFO_0002517	-	Table S4	DNA methylation	Pancreatic ductal adenocarcinoma	-	Beta values	-	Illumina HumanMethylation450	Pancreatic ductal adenocarcinoma and adjacent nontransformed pancreata	-	196	1	-	Missing	None	cg26668151	chr7:157180005	7	157180005	DNAJB6	Open sea	-	-	0.000000000217	-	24500968_pancreatic_ductal_adenocarcinoma
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	-0.047	0.00661	0.00000000022	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.0523236	0.00824526	0.0000000002276182	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0858538	0.0135312	0.0000000002291229	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01410440	chr7:157193063	7	157193063	DNAJB6	Island	-0.012	0.0019	0.00000000025	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0521576	0.00824533	0.0000000002593779	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0521476	0.00824534	0.000000000261419	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0565176	0.00894092	0.0000000002670028	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0520962	0.00824536	0.0000000002721869	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0520799	0.00824537	0.0000000002756972	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg22939563	chr7:157162115	7	157162115	DNAJB6	Open sea	0.03236	0.00486	0.00000000029	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0519772	0.00824541	0.0000000002987841	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0519392	0.00824543	0.0000000003078017	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00553120	chr7:157129669	7	157129669	DNAJB6	Island	-0.00005	0.000008	0.00000000033	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23564939	chr7:157209061	7	157209061	DNAJB6	South shore	0.0017	None	0.00000000034	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0606804	0.00966674	0.0000000003543574	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0517247	0.00824552	0.0000000003639384	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0516118	0.00824557	0.0000000003973589	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	-0.0515406	0.0082456	0.0000000004199852	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0683198	0.0109319	0.0000000004230023	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0515193	0.00824561	0.0000000004269648	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.271503	0.0434641	0.0000000004292428	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	-0.051512	0.00824561	0.0000000004294141	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg05077108	chr7:157200263	7	157200263	DNAJB6	North shelf	-0.01084	0.0017	0.000000000465	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0513615	0.00824567	0.0000000004825321	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	0.229236	0.0368324	0.0000000004959861	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Petersen A-K	KORA F4	24014485	2013-09-06	M00054_tryptophan	EFO_0004727, EFO_0004725	no snps model	Table S2	M00054_tryptophan	DNA methylation	Age, sex, body mass index, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1760	1	Adults	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.45	0.026	0.00000000056	None	24014485_Petersen-A-K_m00054_tryptophan_no_snps_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.051144	0.00824577	0.0000000005707907	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0554698	0.00897624	0.0000000006595193	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0597852	0.00968188	0.0000000006792469	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0509066	0.00824587	0.0000000006851663	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.050872	0.00824588	0.0000000007035737	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0508124	0.00824591	0.0000000007364608	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	-0.0507971	0.00824591	0.0000000007451444	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.0506295	0.00824598	0.0000000008470026	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19249678	chr7:157129666	7	157129666	DNAJB6	Island	-0.000057	0.0000094	0.00000000085	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg07048143	chr7:157199479	7	157199479	DNAJB6	North shelf	0.17804	0.029	0.000000000857	-	25650246_gestational_age
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.251655	0.0410425	0.0000000008890541	None	39706196_Hannah-M.-Smith_bmi_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0053	0.00086	0.00000000092	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18327321	chr7:157193101	7	157193101	DNAJB6	Island	0.0081	None	0.00000000095	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	0.0504365	0.00824606	0.0000000009812055	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.158294	0.0258906	0.0000000009918547	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	0.0503665	0.00824609	0.000000001034843	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg06504624	chr7:157157215	7	157157215	DNAJB6	Open sea	-	-	0.00000000104	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0503377	0.0082461	0.000000001057737	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0503247	0.00824611	0.00000000106824	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.142445	0.0233849	0.000000001142444	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00004836	chr7:157155664	7	157155664	DNAJB6	Open sea	-0.0502217	0.00824615	0.000000001154966	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Liver Cirrhosis	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Liver Cirrhosis	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18325	1	Adults (18-65y)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.015	0.00248	0.0000000012	None	Robert-F-Hillary_Incident_Liver_Cirrhosis_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0667174	0.0109741	0.000000001235256	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0668759	0.0110015	0.000000001240784	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.054606	0.00898649	0.000000001259116	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0500855	0.00824621	0.000000001280341	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg07569018	chr7:157202818	7	157202818	DNAJB6	Island	-0.00399	7e-04	0.00000000147	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0663873	0.0109846	0.000000001543134	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0663224	0.0109832	0.000000001592574	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17529436	chr7:157201728	7	157201728	DNAJB6	North shore	-0.00069	0.00012	0.0000000016	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	-0.00014	0.000024	0.0000000016	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02271119	chr7:157198869	7	157198869	DNAJB6	North shelf	-0.0497008	0.00824637	0.000000001710349	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.00113495	0.00018683	0.00000000172	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0496786	0.00824638	0.000000001739124	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0496711	0.00824638	0.000000001748885	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg13456653	chr7:157130065	7	157130065	DNAJB6	Island	2.096411	0.3486	0.00000000182	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0539721	0.00898414	0.000000001928796	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.06543	0.0108959	0.00000000195807	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0493818	0.0082465	0.000000002171127	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22044861	chr7:157129591	7	157129591	DNAJB6	Island	-0.000067	0.000011	0.0000000022	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.052867	0.00883499	0.000000002230315	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.013	0.0021	0.0000000023	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.15	0.0245	0.0000000025	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.04038	0.00647	0.0000000027	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0490831	0.00824662	0.000000002710795	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0490246	0.00824664	0.000000002830907	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	0.0489468	0.00824668	0.00000000299862	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14567287	chr7:157129156	7	157129156	DNAJB6	Island	0.00022	0.000038	0.0000000033	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0488039	0.00824673	0.000000003332018	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.050845	0.00859541	0.000000003385096	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.0487602	0.00824675	0.000000003441064	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	0.0486919	0.00824678	0.000000003618542	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24185680	chr7:157171288	7	157171288	DNAJB6	Open sea	-0.0486842	0.00824678	0.000000003639143	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0645508	0.0109367	0.000000003665237	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24815507	chr7:157198482	7	157198482	DNAJB6	North shelf	0.01051	0.0017	0.0000000037	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.048642	0.0082468	0.000000003753716	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00004836	chr7:157155664	7	157155664	DNAJB6	Open sea	-0.0486191	0.00824681	0.000000003817348	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26860459	chr7:157199417	7	157199417	DNAJB6	North shelf	0.0031	None	0.000000004	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09710771	chr7:157199809	7	157199809	DNAJB6	North shelf	-0.263119	0.0447161	0.00000000406929	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0574082	0.00975568	0.000000004077513	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0496546	0.00845085	0.000000004302067	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05090392	chr7:157209531	7	157209531	DNAJB6	South shore	0.0023	None	0.0000000046	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0483535	0.00824691	0.000000004637192	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	0.0483272	0.00824692	0.000000004727195	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0503043	0.00858647	0.00000000476901	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0643566	0.0109909	0.000000004859194	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0481966	0.00824698	0.000000005199683	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.034	0.00531	0.0000000056	None	32795589_Kyung-WK_atopy_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.037	0.00634	0.0000000059	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0480068	0.00824705	0.000000005968655	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.0480024	0.00824705	0.00000000598782	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0503862	0.00866357	0.00000000615749	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.0479618	0.00824707	0.000000006166998	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0016	0.00027	0.0000000065	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0477646	0.00824715	0.000000007112768	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25134890	chr7:157200205	7	157200205	DNAJB6	North shelf	0.0045	None	0.0000000073	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0476783	0.00824718	0.000000007569494	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_1
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-	-	0.00000000766	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0476367	0.0082472	0.000000007799891	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01410440	chr7:157193063	7	157193063	DNAJB6	Island	0.01535	0.00254	0.000000008	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0475578	0.00824723	0.000000008255811	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg02994253	chr7:157209799	7	157209799	DNAJB6	North shore	0.16979	0.0295	0.00000000831	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26309551	chr7:157168713	7	157168713	DNAJB6	Open sea	0.0474877	0.00824726	0.000000008682063	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	0.0474135	0.00824729	0.000000009157101	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.236414	0.0411419	0.000000009275475	None	39706196_Hannah-M.-Smith_body_fat_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13456653	chr7:157130065	7	157130065	DNAJB6	Island	0.00038	None	0.0000000095	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0473434	0.00824731	0.000000009628794	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08011146	chr7:157195815	7	157195815	DNAJB6	South shelf	-0.0004	0.00007	0.00000001	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.234699	0.0410163	0.00000001069585	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.00577	0.00101	0.000000011	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.026	0.00463	0.000000011	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0514649	0.00900164	0.00000001103526	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0470696	0.00824742	0.000000011708	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.050635	0.00887849	0.00000001199102	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.060631	0.0106398	0.00000001232009	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0759128	0.0133249	0.00000001242215	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0469761	0.00824746	0.00000001251282	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannon E	None	33646943	2021-02-26	schizophrenia	EFO_0000692	random effects meta-analysis	Supplementary Table 3	DNA methylation	schizophrenia	Age, sex, batch effects, cell composition (reference based), smoking	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	3264	7	Adults	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.99	0.175	0.000000013	None	33646943_Hannon-E_schizophrenia_random_effects_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09903872	chr7:157129451	7	157129451	DNAJB6	Island	0.0023	0.0004	0.000000013	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14567287	chr7:157129156	7	157129156	DNAJB6	Island	0.00025	None	0.000000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01410440	chr7:157193063	7	157193063	DNAJB6	Island	0.0073	None	0.000000014	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23564939	chr7:157209061	7	157209061	DNAJB6	South shore	0.0056	None	0.000000015	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg02271119	chr7:157198869	7	157198869	DNAJB6	North shelf	0.13661	0.0242	0.0000000158	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0466348	0.00824759	0.00000001593466	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05090392	chr7:157209531	7	157209531	DNAJB6	South shore	0.0195	0.00331	0.000000016	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg06504624	chr7:157157215	7	157157215	DNAJB6	Open sea	0.0239	0.00405	0.000000016	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg25134890	chr7:157200205	7	157200205	DNAJB6	North shelf	0.01719	0.00291	0.000000016	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09903872	chr7:157129451	7	157129451	DNAJB6	Island	0.165401	0.0292707	0.00000001621504	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0465371	0.00824763	0.00000001707077	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0465329	0.00824763	0.00000001712165	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0465257	0.00824763	0.00000001720852	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0465072	0.00824764	0.00000001743426	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0496111	0.00880101	0.00000001762476	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0464792	0.00824765	0.00000001778193	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.027	0.00481	0.000000018	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	TMEM106A protein levels (SeqId = 10499-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMEM106A protein levels (SeqId = 10499-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transmembrane protein 106A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.71	0.127	0.000000018	None	Gadd-DA_tmem106a_protein_levels__seqid___10499-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.046386	0.00824768	0.00000001898522	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03937368	chr7:157203490	7	157203490	DNAJB6	North shore	0.0046	None	0.000000019	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03996020	chr7:157180124	7	157180124	DNAJB6	Open sea	-0.012	0.0021	0.000000019	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0463842	0.00824768	0.00000001900993	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	0.01478	0.00252	0.00000002	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0616787	0.0109941	0.00000002057693	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PIN4 protein levels (SeqId = 12718-43)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIN4 protein levels (SeqId = 12718-43)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.71	0.127	0.000000021	None	Gadd-DA_pin4_protein_levels__seqid___12718-43__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.21218	0.0378924	0.00000002181876	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	-0.0461366	0.00824778	0.00000002260892	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0461244	0.00824778	0.00000002280268	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0461046	0.00824779	0.00000002312113	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.054115	0.00968513	0.00000002345563	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	LEMD1 protein levels (SeqId = 8040-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LEMD1 protein levels (SeqId = 8040-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: LEM domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.71	0.127	0.000000024	None	Gadd-DA_lemd1_protein_levels__seqid___8040-9__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.265924	0.04764	0.00000002412198	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0460408	0.00824782	0.0000000241735	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	0.0460319	0.00824782	0.00000002432411	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Li M	None	33279932	2020-12-14	Schizophrenia	EFO_0000692	main	Table 1	DNA methylation	Schizophrenia	age, sex, batch effects	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	999	None	Adults	Both	East Asian	cg08011146	chr7:157195815	7	157195815	DNAJB6	South shelf	-0.00659	0.00118	0.000000025	None	33279932_Li-M_schizophrenia_main
Gadd DA	Generation Scotland	35945220	31/07/2022	DYNLRB1 protein levels (SeqId = 3845-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DYNLRB1 protein levels (SeqId = 3845-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dynein light chain roadblock-type 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.71	0.127	0.000000025	None	Gadd-DA_dynlrb1_protein_levels__seqid___3845-51__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0459874	0.00824784	0.0000000250904	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0459632	0.00824785	0.00000002551529	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg03559568	chr7:157208968	7	157208968	DNAJB6	Island	0.01229	0.00212	0.000000026	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0459156	0.00824786	0.00000002637585	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.0458949	0.00824787	0.00000002675762	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01766193	chr7:157202248	7	157202248	DNAJB6	North shore	0.0016	None	0.000000029	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.04575	0.00824793	0.00000002958947	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.045703	0.00824794	0.00000003056921	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.025	0.00452	0.000000032	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0496977	0.00899345	0.00000003332263	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CUL4B protein levels (SeqId = 13743-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CUL4B protein levels (SeqId = 13743-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cullin-4B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.7	0.127	0.000000034	None	Gadd-DA_cul4b_protein_levels__seqid___13743-56__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0454428	0.00824804	0.00000003658725	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03559568	chr7:157208968	7	157208968	DNAJB6	Island	-0.00085	0.00015	0.00000004	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27023755	chr7:157200373	7	157200373	DNAJB6	North shore	0.00093	None	0.00000004	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.237197	0.0431952	0.00000004046336	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	0.032	0.00543	0.000000042	None	32795589_Kyung-WK_eosinophilia_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19428573	chr7:157200793	7	157200793	DNAJB6	North shore	0.243617	0.0444267	0.0000000422631	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0452017	0.00824813	0.00000004317834	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	-0.0451536	0.00824815	0.00000004462155	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg12381188	chr7:157199595	7	157199595	DNAJB6	North shelf	0.11726	0.0214	0.0000000455	-	25650246_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	RAP1GDS1 protein levels (SeqId = 14106-46)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAP1GDS1 protein levels (SeqId = 14106-46)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rap1 GTPase-GDP dissociation stimulator 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.7	0.127	0.000000046	None	Gadd-DA_rap1gds1_protein_levels__seqid___14106-46__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19428573	chr7:157200793	7	157200793	DNAJB6	North shore	0.242284	0.0443254	0.00000004666	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0450786	0.00824818	0.0000000469712	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0450627	0.00824818	0.00000004748492	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF4H protein levels (SeqId = 5885-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF4H protein levels (SeqId = 5885-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 4H	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.69	0.127	0.000000049	None	Gadd-DA_eif4h_protein_levels__seqid___5885-55__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0477053	0.00874198	0.00000004919971	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.260707	0.0477944	0.00000004967703	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Hernandez-Vargas H	-	25855716	2015-04-07	Prenatal exposure to aflatoxin B1	CHEBI_2504	-	Table 2	DNA methylation	Prenatal exposure to aflatoxin B1	Sex, season of conception and technical covariates	M values	-	Illumina HumanMethylation450	White blood cells	-	115	1	0.3	Both	African	cg21240861	chr7:157129652	7	157129652	DNAJB6	Island	-	-	0.00000005	-	25855716_prenatal_exposure_to_aflatoxin_b1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0449742	0.00824822	0.00000005044219	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	1.3	0.23	0.000000051	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	SNX4 protein levels (SeqId = 3903-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNX4 protein levels (SeqId = 3903-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sorting nexin-4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.69	0.127	0.000000052	None	Gadd-DA_snx4_protein_levels__seqid___3903-49__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.039	0.00713	0.000000053	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0448977	0.00824825	0.0000000531408	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0448367	0.00824827	0.00000005539446	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23768894	chr7:157140029	7	157140029	DNAJB6	Open sea	0.00053	None	0.000000058	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.044725	0.00824831	0.00000005975881	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0525777	0.00970154	0.00000006070475	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0446875	0.00824832	0.00000006129873	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0446462	0.00824834	0.00000006303938	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14567287	chr7:157129156	7	157129156	DNAJB6	Island	0.00088	None	0.000000065	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	HEXIM1 protein levels (SeqId = 15596-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HEXIM1 protein levels (SeqId = 15596-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein HEXIM1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.69	0.127	0.000000065	None	Gadd-DA_hexim1_protein_levels__seqid___15596-7__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg13858484	chr7:157162202	7	157162202	DNAJB6	Open sea	1.077842	0.1996	0.0000000666	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0445576	0.00824837	0.00000006693355	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0445394	0.00824838	0.00000006776291	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg21240861	chr7:157129652	7	157129652	DNAJB6	Island	0.00403	7e-04	0.0000000678	-	23334450_rheumatoid_arthritis
Gadd DA	Generation Scotland	35945220	31/07/2022	LDLRAP1 protein levels (SeqId = 18183-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LDLRAP1 protein levels (SeqId = 18183-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Low density lipoprotein receptor adapter protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.69	0.127	0.000000069	None	Gadd-DA_ldlrap1_protein_levels__seqid___18183-3__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.215635	0.039971	0.00000006945678	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0445016	0.00824839	0.00000006951694	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SNTB1 protein levels (SeqId = 9078-207)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNTB1 protein levels (SeqId = 9078-207)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-1-syntrophin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.69	0.127	0.000000071	None	Gadd-DA_sntb1_protein_levels__seqid___9078-207__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0589471	0.0109341	0.00000007109529	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PLD3 protein levels (SeqId = 10948-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLD3 protein levels (SeqId = 10948-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phospholipase D3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.000000072	None	Gadd-DA_pld3_protein_levels__seqid___10948-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS6KB1 protein levels (SeqId = 15608-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS6KB1 protein levels (SeqId = 15608-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribosomal protein S6 kinase beta-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.000000072	None	Gadd-DA_rps6kb1_protein_levels__seqid___15608-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EFNB1 protein levels (SeqId = 13104-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EFNB1 protein levels (SeqId = 13104-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ephrin-B1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.69	0.127	0.000000072	None	Gadd-DA_efnb1_protein_levels__seqid___13104-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAWR protein levels (SeqId = 9565-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAWR protein levels (SeqId = 9565-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PRKC apoptosis WT1 regulator protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.000000073	None	Gadd-DA_pawr_protein_levels__seqid___9565-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0444107	0.00824843	0.00000007391076	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05090392	chr7:157209531	7	157209531	DNAJB6	South shore	0.016	0.0031	0.000000074	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0443825	0.00824844	0.00000007532666	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	HSPC159 protein levels (SeqId = 18236-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSPC159 protein levels (SeqId = 18236-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Galectin-related protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.000000078	None	Gadd-DA_hspc159_protein_levels__seqid___18236-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	0.0443238	0.00824846	0.00000007836526	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0482467	0.00898497	0.00000008006275	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	-0.0442772	0.00824847	0.000000080857	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPKAPK2 protein levels (SeqId = 3820-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPKAPK2 protein levels (SeqId = 3820-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAP kinase-activated protein kinase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.000000081	None	Gadd-DA_mapkapk2_protein_levels__seqid___3820-68__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.242851	0.0452586	0.0000000815558	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	CRAT protein levels (SeqId = 12637-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRAT protein levels (SeqId = 12637-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carnitine O-acetyltransferase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.000000084	None	Gadd-DA_crat_protein_levels__seqid___12637-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0528715	0.00987015	0.00000008603094	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB5A protein levels (SeqId = 17205-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB5A protein levels (SeqId = 17205-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-5A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.000000088	None	Gadd-DA_rab5a_protein_levels__seqid___17205-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DKK4 protein levels (SeqId = 3365-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DKK4 protein levels (SeqId = 3365-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dickkopf-related protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.00000009	None	Gadd-DA_dkk4_protein_levels__seqid___3365-7__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.446222	0.0834369	0.0000000900551	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0661306	0.0123692	0.00000009108031	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	CDKN2D protein levels (SeqId = 12376-85)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDKN2D protein levels (SeqId = 12376-85)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cyclin-dependent kinase 4 inhibitor D	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.000000093	None	Gadd-DA_cdkn2d_protein_levels__seqid___12376-85__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2E1 protein levels (SeqId = 14326-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2E1 protein levels (SeqId = 14326-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 E1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.000000094	None	Gadd-DA_ube2e1_protein_levels__seqid___14326-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	-0.0440205	0.00824857	0.00000009603514	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0525581	0.00985112	0.00000009683629	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0440048	0.00824857	0.00000009704952	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TOR1AIP1 protein levels (SeqId = 10606-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TOR1AIP1 protein levels (SeqId = 10606-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Torsin-1A-interacting protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.68	0.127	0.000000098	None	Gadd-DA_tor1aip1_protein_levels__seqid___10606-34__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.0439899	0.00824858	0.00000009802254	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21240861	chr7:157129652	7	157129652	DNAJB6	Island	0.00206	0.00037	0.0000001	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0439342	0.0082486	0.0000001017318	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.256978	0.048344	0.0000001076241	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	SUMO2 protein levels (SeqId = 19555-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUMO2 protein levels (SeqId = 19555-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Small ubiquitin-related modifier 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000011	None	Gadd-DA_sumo2_protein_levels__seqid___19555-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0583265	0.0109895	0.0000001127584	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0437759	0.00824866	0.000000113043	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0437757	0.00824866	0.0000001130598	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0437029	0.00824868	0.0000001186643	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0436945	0.00824869	0.0000001193273	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.04174	0.00759	0.00000012	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19858151	chr7:157200669	7	157200669	DNAJB6	North shore	0.02916	0.00531	0.00000012	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	OVCA2 protein levels (SeqId = 17697-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	OVCA2 protein levels (SeqId = 17697-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Esterase OVCA2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000012	None	Gadd-DA_ovca2_protein_levels__seqid___17697-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS6KA3 protein levels (SeqId = 3469-74)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS6KA3 protein levels (SeqId = 3469-74)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribosomal protein S6 kinase alpha-3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000012	None	Gadd-DA_rps6ka3_protein_levels__seqid___3469-74__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg08010530	chr7:157200028	7	157200028	DNAJB6	North shelf	-0.163691	0.0309134	0.0000001202911	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	CPXM1 protein levels (SeqId = 6255-74)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CPXM1 protein levels (SeqId = 6255-74)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable carboxypeptidase X1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000013	None	Gadd-DA_cpxm1_protein_levels__seqid___6255-74__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANXA6 protein levels (SeqId = 5335-73)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANXA6 protein levels (SeqId = 5335-73)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Annexin A6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000013	None	Gadd-DA_anxa6_protein_levels__seqid___5335-73__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0487621	0.00923423	0.0000001306118	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0435369	0.00824874	0.0000001324547	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0435362	0.00824874	0.0000001325204	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.043531	0.00824874	0.0000001329773	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.256678	0.048658	0.0000001342523	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	ACADVL protein levels (SeqId = 19262-219)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACADVL protein levels (SeqId = 19262-219)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000014	None	Gadd-DA_acadvl_protein_levels__seqid___19262-219__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BPNT1 protein levels (SeqId = 17814-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BPNT1 protein levels (SeqId = 17814-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 3'(2'),5'-bisphosphate nucleotidase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000014	None	Gadd-DA_bpnt1_protein_levels__seqid___17814-8__somascan_protein_measurement
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-2.2	0.425	0.00000014	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0471092	0.00894589	0.0000001413862	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0434297	0.00824878	0.0000001421796	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.00079254	0.00014972	0.000000146	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Li M	None	33279932	2020-12-14	Schizophrenia	EFO_0000692	adjusted for cell composition	Table 1	DNA methylation	Schizophrenia	age, sex, batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	999	None	Adults	Both	East Asian	cg08011146	chr7:157195815	7	157195815	DNAJB6	South shelf	None	None	0.00000015	None	33279932_Li-M_schizophrenia_adjusted_for_cell_composition
Gadd DA	Generation Scotland	35945220	31/07/2022	ANXA4 protein levels (SeqId = 17164-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANXA4 protein levels (SeqId = 17164-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Annexin A4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000015	None	Gadd-DA_anxa4_protein_levels__seqid___17164-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNTA1 protein levels (SeqId = 19274-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNTA1 protein levels (SeqId = 19274-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-1-syntrophin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000015	None	Gadd-DA_snta1_protein_levels__seqid___19274-80__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NMI protein levels (SeqId = 17512-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NMI protein levels (SeqId = 17512-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-myc-interactor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000015	None	Gadd-DA_nmi_protein_levels__seqid___17512-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPHK1 protein levels (SeqId = 4294-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPHK1 protein levels (SeqId = 4294-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sphingosine kinase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000015	None	Gadd-DA_sphk1_protein_levels__seqid___4294-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0468208	0.00891861	0.0000001544	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0432976	0.00824883	0.0000001551081	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0432716	0.00824884	0.0000001577877	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	RAC2 protein levels (SeqId = 18950-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAC2 protein levels (SeqId = 18950-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related C3 botulinum toxin substrate 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000016	None	Gadd-DA_rac2_protein_levels__seqid___18950-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AKT1 protein levels (SeqId = 3392-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKT1 protein levels (SeqId = 3392-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RAC-gamma serine/threonine-protein kinase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000016	None	Gadd-DA_akt1_protein_levels__seqid___3392-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IDI1 protein levels (SeqId = 17712-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IDI1 protein levels (SeqId = 17712-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Isopentenyl-diphosphate Delta-isomerase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000016	None	Gadd-DA_idi1_protein_levels__seqid___17712-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0575007	0.0109766	0.0000001641268	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0431866	0.00824887	0.0000001668498	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.043159	0.00824888	0.0000001698983	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Fernandez-Jimenez N	Pregnancy And Childhood Epigenetics (PACE)	None	None	maternal pre-pregnancy body mass index	EFO_0004340	inverse variance-weighted fixed effects meta-analysis adjusted by cellular heterogeneity	https://doi.org/10.5281/zenodo.7314534	DNA methylation	maternal pre-pregnancy body mass index	Cell composition (reference free), maternal age, parity, maternal education, maternal smoking	Beta values	kg/m2	Illumina HumanMethylation450	Placenta	None	2631	10	Infants	Both	European, Unclear	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0013	0.00025	0.00000017	None	Fernandez-Jimenez-N_maternal_pre-pregnancy_body_mass_index_inverse_variance-weighted_fixed_effects_meta-analysis_adjusted_by_cellular_heterogeneity
Gadd DA	Generation Scotland	35945220	31/07/2022	NUDC protein levels (SeqId = 8887-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUDC protein levels (SeqId = 8887-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear migration protein nudC	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000017	None	Gadd-DA_nudc_protein_levels__seqid___8887-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DTD1 protein levels (SeqId = 19194-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DTD1 protein levels (SeqId = 19194-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: D-aminoacyl-tRNA deacylase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.67	0.127	0.00000017	None	Gadd-DA_dtd1_protein_levels__seqid___19194-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TRIP10 protein levels (SeqId = 17676-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TRIP10 protein levels (SeqId = 17676-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cdc42-interacting protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000018	None	Gadd-DA_trip10_protein_levels__seqid___17676-13__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0430652	0.00824891	0.0000001806738	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.433994	0.0832051	0.0000001849805	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0079	0.0015	0.00000019	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	AHCYL1 protein levels (SeqId = 12652-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AHCYL1 protein levels (SeqId = 12652-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: S-adenosylhomocysteine hydrolase-like protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000019	None	Gadd-DA_ahcyl1_protein_levels__seqid___12652-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DKK2 protein levels (SeqId = 15678-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DKK2 protein levels (SeqId = 15678-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dickkopf-related protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000019	None	Gadd-DA_dkk2_protein_levels__seqid___15678-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CKS1B protein levels (SeqId = 12530-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CKS1B protein levels (SeqId = 12530-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cyclin-dependent kinases regulatory subunit 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000019	None	Gadd-DA_cks1b_protein_levels__seqid___12530-14__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0429224	0.00824896	0.0000001983389	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GRB2 protein levels (SeqId = 5464-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRB2 protein levels (SeqId = 5464-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Growth factor receptor-bound protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.0000002	None	Gadd-DA_grb2_protein_levels__seqid___5464-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDX19A protein levels (SeqId = 18813-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDX19A protein levels (SeqId = 18813-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ATP-dependent RNA helicase DDX19A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.0000002	None	Gadd-DA_ddx19a_protein_levels__seqid___18813-15__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0428822	0.00824898	0.000000203609	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PTK2B protein levels (SeqId = 8918-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTK2B protein levels (SeqId = 8918-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein-tyrosine kinase 2-beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000021	None	Gadd-DA_ptk2b_protein_levels__seqid___8918-64__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C11orf68 protein levels (SeqId = 8307-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C11orf68 protein levels (SeqId = 8307-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UPF0696 protein C11orf68	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000021	None	Gadd-DA_c11orf68_protein_levels__seqid___8307-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSD17B10 protein levels (SeqId = 4217-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSD17B10 protein levels (SeqId = 4217-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 3-hydroxyacyl-CoA dehydrogenase type-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000021	None	Gadd-DA_hsd17b10_protein_levels__seqid___4217-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0428046	0.008249	0.0000002141679	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	0.0427905	0.00824901	0.0000002161482	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04430780	chr7:157199439	7	157199439	DNAJB6	North shelf	-0.00084	0.00016	0.00000022	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	CASP3 protein levels (SeqId = 3593-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASP3 protein levels (SeqId = 3593-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Caspase-3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000022	None	Gadd-DA_casp3_protein_levels__seqid___3593-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZFAND1 protein levels (SeqId = 19173-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZFAND1 protein levels (SeqId = 19173-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AN1-type zinc finger protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000022	None	Gadd-DA_zfand1_protein_levels__seqid___19173-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAT3 protein levels (SeqId = 10346-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAT3 protein levels (SeqId = 10346-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal transducer and activator of transcription 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000022	None	Gadd-DA_stat3_protein_levels__seqid___10346-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GAP43 protein levels (SeqId = 15325-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GAP43 protein levels (SeqId = 15325-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Neuromodulin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000022	None	Gadd-DA_gap43_protein_levels__seqid___15325-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SMAP1 protein levels (SeqId = 11649-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMAP1 protein levels (SeqId = 11649-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Stromal membrane-associated protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000022	None	Gadd-DA_smap1_protein_levels__seqid___11649-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	0.0523353	0.010099	0.0000002221795	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0427428	0.00824903	0.000000222956	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0461138	0.00890368	0.0000002258054	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0427009	0.00824904	0.0000002291062	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	UNC45A protein levels (SeqId = 13082-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UNC45A protein levels (SeqId = 13082-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein unc-45 homolog A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000023	None	Gadd-DA_unc45a_protein_levels__seqid___13082-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TFAM protein levels (SeqId = 9952-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TFAM protein levels (SeqId = 9952-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription factor A, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000023	None	Gadd-DA_tfam_protein_levels__seqid___9952-57__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	0.0426782	0.00824905	0.000000232521	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04430780	chr7:157199439	7	157199439	DNAJB6	North shelf	0.0011	None	0.00000024	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	TBCE protein levels (SeqId = 11211-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TBCE protein levels (SeqId = 11211-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tubulin-specific chaperone E	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000024	None	Gadd-DA_tbce_protein_levels__seqid___11211-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRDX3 protein levels (SeqId = 8358-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRDX3 protein levels (SeqId = 8358-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin-dependent peroxide reductase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000024	None	Gadd-DA_prdx3_protein_levels__seqid___8358-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SAR1A protein levels (SeqId = 17726-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SAR1A protein levels (SeqId = 17726-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GTP-binding protein SAR1a	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000024	None	Gadd-DA_sar1a_protein_levels__seqid___17726-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KPNB1 protein levels (SeqId = 3887-90)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KPNB1 protein levels (SeqId = 3887-90)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Importin subunit beta-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000024	None	Gadd-DA_kpnb1_protein_levels__seqid___3887-90__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	ch.7.3356624R	chr7:157205374	7	157205374	DNAJB6	North shore	0.0021	None	0.00000024	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0085	0.0017	0.00000025	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.0425146	0.00824911	0.0000002585117	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NPLOC4 protein levels (SeqId = 12993-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NPLOC4 protein levels (SeqId = 12993-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear protein localization protein 4 homolog	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000026	None	Gadd-DA_nploc4_protein_levels__seqid___12993-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MTHFS protein levels (SeqId = 14107-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MTHFS protein levels (SeqId = 14107-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 5-formyltetrahydrofolate cyclo-ligase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000026	None	Gadd-DA_mthfs_protein_levels__seqid___14107-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2I protein levels (SeqId = 2877-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2I protein levels (SeqId = 2877-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SUMO-conjugating enzyme UBC9	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.66	0.127	0.00000026	None	Gadd-DA_ube2i_protein_levels__seqid___2877-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACBD6 protein levels (SeqId = 10075-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACBD6 protein levels (SeqId = 10075-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-CoA-binding domain-containing protein 6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000027	None	Gadd-DA_acbd6_protein_levels__seqid___10075-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GGA1 protein levels (SeqId = 13594-158)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GGA1 protein levels (SeqId = 13594-158)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor-binding protein GGA1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000027	None	Gadd-DA_gga1_protein_levels__seqid___13594-158__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TBPL1 protein levels (SeqId = 18434-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TBPL1 protein levels (SeqId = 18434-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: TATA box-binding protein-like protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000027	None	Gadd-DA_tbpl1_protein_levels__seqid___18434-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PABPN1 protein levels (SeqId = 8921-139)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PABPN1 protein levels (SeqId = 8921-139)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Polyadenylate-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000027	None	Gadd-DA_pabpn1_protein_levels__seqid___8921-139__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDX58 protein levels (SeqId = 12382-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDX58 protein levels (SeqId = 12382-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable ATP-dependent RNA helicase DDX58	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000028	None	Gadd-DA_ddx58_protein_levels__seqid___12382-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AMPD2 protein levels (SeqId = 18403-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AMPD2 protein levels (SeqId = 18403-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AMP deaminase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000028	None	Gadd-DA_ampd2_protein_levels__seqid___18403-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UFC1 protein levels (SeqId = 3405-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UFC1 protein levels (SeqId = 3405-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-fold modifier-conjugating enzyme 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000029	None	Gadd-DA_ufc1_protein_levels__seqid___3405-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0423123	0.00824918	0.0000002945672	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	INPP5B protein levels (SeqId = 12641-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	INPP5B protein levels (SeqId = 12641-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Type II inositol 1,4,5-trisphosphate 5-phosphatase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.0000003	None	Gadd-DA_inpp5b_protein_levels__seqid___12641-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ABHD10 protein levels (SeqId = 17370-186)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ABHD10 protein levels (SeqId = 17370-186)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mycophenolic acid acyl-glucuronide esterase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.0000003	None	Gadd-DA_abhd10_protein_levels__seqid___17370-186__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CRK protein levels (SeqId = 4976-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRK protein levels (SeqId = 4976-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adapter molecule crk	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.0000003	None	Gadd-DA_crk_protein_levels__seqid___4976-57__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0422827	0.00824919	0.000000300227	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.135365	0.0264238	0.0000003042252	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0500135	0.00976348	0.0000003053268	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	ACOT13 protein levels (SeqId = 17675-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACOT13 protein levels (SeqId = 17675-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-coenzyme A thioesterase 13	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000031	None	Gadd-DA_acot13_protein_levels__seqid___17675-17__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0422185	0.00824921	0.0000003128913	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00004836	chr7:157155664	7	157155664	DNAJB6	Open sea	-0.0422108	0.00824921	0.0000003144477	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0454393	0.00888507	0.0000003191715	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	SUMO3 protein levels (SeqId = 14623-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUMO3 protein levels (SeqId = 14623-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Small ubiquitin-related modifier 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000032	None	Gadd-DA_sumo3_protein_levels__seqid___14623-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NAPG protein levels (SeqId = 17773-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAPG protein levels (SeqId = 17773-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-soluble NSF attachment protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000032	None	Gadd-DA_napg_protein_levels__seqid___17773-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PIP4K2A protein levels (SeqId = 12697-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIP4K2A protein levels (SeqId = 12697-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000032	None	Gadd-DA_pip4k2a_protein_levels__seqid___12697-30__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0421426	0.00824924	0.0000003285086	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ENAH protein levels (SeqId = 9757-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ENAH protein levels (SeqId = 9757-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein enabled homolog	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000033	None	Gadd-DA_enah_protein_levels__seqid___9757-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PA2G4 protein levels (SeqId = 4258-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PA2G4 protein levels (SeqId = 4258-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proliferation-associated protein 2G4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000033	None	Gadd-DA_pa2g4_protein_levels__seqid___4258-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFSF12 protein levels (SeqId = 5939-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFSF12 protein levels (SeqId = 5939-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor ligand superfamily member 12	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000033	None	Gadd-DA_tnfsf12_protein_levels__seqid___5939-42__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0421061	0.00824925	0.0000003363	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ACSF2 protein levels (SeqId = 17466-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACSF2 protein levels (SeqId = 17466-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-CoA synthetase family member 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000034	None	Gadd-DA_acsf2_protein_levels__seqid___17466-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARRB1 protein levels (SeqId = 12643-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARRB1 protein levels (SeqId = 12643-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-arrestin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000034	None	Gadd-DA_arrb1_protein_levels__seqid___12643-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK9 protein levels (SeqId = 15604-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK9 protein levels (SeqId = 15604-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 9	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000034	None	Gadd-DA_mapk9_protein_levels__seqid___15604-18__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0420878	0.00824926	0.0000003402537	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19249678	chr7:157129666	7	157129666	DNAJB6	Island	0.000066	None	0.00000035	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	AKT1 protein levels (SeqId = 15627-83)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKT1 protein levels (SeqId = 15627-83)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RAC-alpha serine/threonine-protein kinase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000035	None	Gadd-DA_akt1_protein_levels__seqid___15627-83__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APOBEC3G protein levels (SeqId = 13930-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APOBEC3G protein levels (SeqId = 13930-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA dC->dU-editing enzyme APOBEC-3G	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000035	None	Gadd-DA_apobec3g_protein_levels__seqid___13930-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3GL3 protein levels (SeqId = 18318-98)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3GL3 protein levels (SeqId = 18318-98)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endophilin-A3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000035	None	Gadd-DA_sh3gl3_protein_levels__seqid___18318-98__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	YARS protein levels (SeqId = 19270-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YARS protein levels (SeqId = 19270-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine--tRNA ligase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000035	None	Gadd-DA_yars_protein_levels__seqid___19270-26__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12910268	chr7:157185351	7	157185351	DNAJB6	Open sea	0.0043	None	0.00000036	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	PGR protein levels (SeqId = 15693-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGR protein levels (SeqId = 15693-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Progesterone receptor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000036	None	Gadd-DA_pgr_protein_levels__seqid___15693-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3BGRL2 protein levels (SeqId = 19113-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3BGRL2 protein levels (SeqId = 19113-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SH3 domain-binding glutamic acid-rich-like protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000036	None	Gadd-DA_sh3bgrl2_protein_levels__seqid___19113-66__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0419984	0.00824929	0.0000003602842	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0559175	0.010987	0.0000003635502	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0015	None	0.00000037	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	AIP protein levels (SeqId = 3839-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AIP protein levels (SeqId = 3839-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AH receptor-interacting protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000037	None	Gadd-DA_aip_protein_levels__seqid___3839-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RBBP6 protein levels (SeqId = 9887-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RBBP6 protein levels (SeqId = 9887-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase RBBP6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000037	None	Gadd-DA_rbbp6_protein_levels__seqid___9887-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAC1 protein levels (SeqId = 2870-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAC1 protein levels (SeqId = 2870-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related C3 botulinum toxin substrate 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000037	None	Gadd-DA_rac1_protein_levels__seqid___2870-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HADH protein levels (SeqId = 17739-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HADH protein levels (SeqId = 17739-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000037	None	Gadd-DA_hadh_protein_levels__seqid___17739-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0419422	0.00824931	0.000000373468	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	0.0427732	0.00841763	0.0000003792988	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0537561	0.0105794	0.0000003796118	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17483	1	Adults (18-65y)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.036	0.00715	0.00000038	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	GMPR2 protein levels (SeqId = 19446-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GMPR2 protein levels (SeqId = 19446-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GMP reductase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000038	None	Gadd-DA_gmpr2_protein_levels__seqid___19446-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPCS protein levels (SeqId = 17843-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPCS protein levels (SeqId = 17843-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphopantothenate--cysteine ligase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000038	None	Gadd-DA_ppcs_protein_levels__seqid___17843-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CFL1 protein levels (SeqId = 4203-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CFL1 protein levels (SeqId = 4203-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cofilin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000039	None	Gadd-DA_cfl1_protein_levels__seqid___4203-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RNF114 protein levels (SeqId = 9957-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RNF114 protein levels (SeqId = 9957-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase RNF114	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.00000039	None	Gadd-DA_rnf114_protein_levels__seqid___9957-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0558552	0.0110073	0.0000003934715	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0418603	0.00824933	0.0000003935083	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ASNA1 protein levels (SeqId = 13620-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASNA1 protein levels (SeqId = 13620-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ATPase ASNA1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.0000004	None	Gadd-DA_asna1_protein_levels__seqid___13620-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANXA11 protein levels (SeqId = 17513-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANXA11 protein levels (SeqId = 17513-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Annexin A11	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.0000004	None	Gadd-DA_anxa11_protein_levels__seqid___17513-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ROCK2 protein levels (SeqId = 13654-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ROCK2 protein levels (SeqId = 13654-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho-associated protein kinase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.0000004	None	Gadd-DA_rock2_protein_levels__seqid___13654-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB13 protein levels (SeqId = 19282-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB13 protein levels (SeqId = 19282-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-13	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.0000004	None	Gadd-DA_rab13_protein_levels__seqid___19282-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DOK1 protein levels (SeqId = 16831-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DOK1 protein levels (SeqId = 16831-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Docking protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.65	0.127	0.0000004	None	Gadd-DA_dok1_protein_levels__seqid___16831-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0418035	0.00824935	0.0000004079918	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM162A protein levels (SeqId = 6531-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM162A protein levels (SeqId = 6531-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM162A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000041	None	Gadd-DA_fam162a_protein_levels__seqid___6531-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DTYMK protein levels (SeqId = 19504-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DTYMK protein levels (SeqId = 19504-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thymidylate kinase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000041	None	Gadd-DA_dtymk_protein_levels__seqid___19504-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DKK1 protein levels (SeqId = 3535-84)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DKK1 protein levels (SeqId = 3535-84)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dickkopf-related protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000041	None	Gadd-DA_dkk1_protein_levels__seqid___3535-84__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PURB protein levels (SeqId = 18300-39)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PURB protein levels (SeqId = 18300-39)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcriptional activator protein Pur-beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000041	None	Gadd-DA_purb_protein_levels__seqid___18300-39__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0417697	0.00824937	0.0000004168659	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0451304	0.00891331	0.0000004171571	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.0417682	0.00824937	0.0000004172728	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3GL2 protein levels (SeqId = 12499-108)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3GL2 protein levels (SeqId = 12499-108)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endophilin-A1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000042	None	Gadd-DA_sh3gl2_protein_levels__seqid___12499-108__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FEV protein levels (SeqId = 12740-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FEV protein levels (SeqId = 12740-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FEV	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000042	None	Gadd-DA_fev_protein_levels__seqid___12740-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MTIF3 protein levels (SeqId = 7852-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MTIF3 protein levels (SeqId = 7852-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Translation initiation factor IF-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000042	None	Gadd-DA_mtif3_protein_levels__seqid___7852-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARL6IP5 protein levels (SeqId = 13503-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARL6IP5 protein levels (SeqId = 13503-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PRA1 family protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000042	None	Gadd-DA_arl6ip5_protein_levels__seqid___13503-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TBCB protein levels (SeqId = 17686-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TBCB protein levels (SeqId = 17686-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tubulin-folding cofactor B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000042	None	Gadd-DA_tbcb_protein_levels__seqid___17686-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DARS protein levels (SeqId = 12675-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DARS protein levels (SeqId = 12675-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aspartate--tRNA ligase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000042	None	Gadd-DA_dars_protein_levels__seqid___12675-14__somascan_protein_measurement
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-1	0.2	0.00000042	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	-0.0417291	0.00824938	0.0000004277715	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	LANCL1 protein levels (SeqId = 13986-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LANCL1 protein levels (SeqId = 13986-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase LANCL1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000043	None	Gadd-DA_lancl1_protein_levels__seqid___13986-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDIA5 protein levels (SeqId = 5593-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDIA5 protein levels (SeqId = 5593-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein disulfide-isomerase A5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000043	None	Gadd-DA_pdia5_protein_levels__seqid___5593-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPE protein levels (SeqId = 12646-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPE protein levels (SeqId = 12646-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribulose-phosphate 3-epimerase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000043	None	Gadd-DA_rpe_protein_levels__seqid___12646-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0417198	0.00824938	0.0000004303146	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0557763	0.0110303	0.0000004318455	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	0.0416987	0.00824939	0.0000004361272	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0426118	0.0084306	0.0000004368863	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKCA protein levels (SeqId = 2644-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKCA protein levels (SeqId = 2644-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein kinase C alpha type	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000044	None	Gadd-DA_prkca_protein_levels__seqid___2644-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DARS2 protein levels (SeqId = 12395-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DARS2 protein levels (SeqId = 12395-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aspartate--tRNA ligase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000044	None	Gadd-DA_dars2_protein_levels__seqid___12395-86__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COX5A protein levels (SeqId = 18226-148)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COX5A protein levels (SeqId = 18226-148)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytochrome c oxidase subunit 5A, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000044	None	Gadd-DA_cox5a_protein_levels__seqid___18226-148__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPF protein levels (SeqId = 9764-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPF protein levels (SeqId = 9764-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein F	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000044	None	Gadd-DA_hnrnpf_protein_levels__seqid___9764-79__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0550282	0.0108928	0.000000442899	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0478985	0.0094904	0.0000004540768	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0416345	0.00824941	0.0000004542647	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ANXA7 protein levels (SeqId = 14203-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANXA7 protein levels (SeqId = 14203-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Annexin A7	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000046	None	Gadd-DA_anxa7_protein_levels__seqid___14203-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPIF protein levels (SeqId = 5248-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPIF protein levels (SeqId = 5248-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase F, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000046	None	Gadd-DA_ppif_protein_levels__seqid___5248-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRDX1 protein levels (SeqId = 3855-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRDX1 protein levels (SeqId = 3855-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxiredoxin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000046	None	Gadd-DA_prdx1_protein_levels__seqid___3855-56__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05077108	chr7:157200263	7	157200263	DNAJB6	North shelf	0.0007	None	0.00000047	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF4G2 protein levels (SeqId = 4230-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF4G2 protein levels (SeqId = 4230-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 4 gamma 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000047	None	Gadd-DA_eif4g2_protein_levels__seqid___4230-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SUGT1 protein levels (SeqId = 17818-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUGT1 protein levels (SeqId = 17818-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein SGT1 homolog	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000047	None	Gadd-DA_sugt1_protein_levels__seqid___17818-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB5B protein levels (SeqId = 19222-124)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB5B protein levels (SeqId = 19222-124)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-5B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000048	None	Gadd-DA_rab5b_protein_levels__seqid___19222-124__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ALDH6A1 protein levels (SeqId = 19136-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALDH6A1 protein levels (SeqId = 19136-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000048	None	Gadd-DA_aldh6a1_protein_levels__seqid___19136-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM49B protein levels (SeqId = 19176-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM49B protein levels (SeqId = 19176-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM49B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000048	None	Gadd-DA_fam49b_protein_levels__seqid___19176-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDC42 protein levels (SeqId = 9840-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDC42 protein levels (SeqId = 9840-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cell division control protein 42 homolog	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000048	None	Gadd-DA_cdc42_protein_levels__seqid___9840-2__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02994253	chr7:157209799	7	157209799	DNAJB6	North shore	-0.0068	0.0013	0.00000049	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB6B protein levels (SeqId = 14271-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB6B protein levels (SeqId = 14271-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-6B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.126	0.00000049	None	Gadd-DA_rab6b_protein_levels__seqid___14271-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB1 protein levels (SeqId = 3852-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB1 protein levels (SeqId = 3852-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000049	None	Gadd-DA_dnajb1_protein_levels__seqid___3852-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PMVK protein levels (SeqId = 12450-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PMVK protein levels (SeqId = 12450-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphomevalonate kinase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000049	None	Gadd-DA_pmvk_protein_levels__seqid___12450-42__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0414851	0.00824946	0.0000004993291	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SMAD1 protein levels (SeqId = 9838-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMAD1 protein levels (SeqId = 9838-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mothers against decapentaplegic homolog 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.0000005	None	Gadd-DA_smad1_protein_levels__seqid___9838-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF4 protein levels (SeqId = 4123-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF4 protein levels (SeqId = 4123-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.629	0.125	0.0000005	None	Gadd-DA_fgf4_protein_levels__seqid___4123-60__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0557713	0.0110945	0.0000005042623	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	SNUPN protein levels (SeqId = 17765-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNUPN protein levels (SeqId = 17765-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Snurportin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000051	None	Gadd-DA_snupn_protein_levels__seqid___17765-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PTP4A2 protein levels (SeqId = 11699-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTP4A2 protein levels (SeqId = 11699-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein tyrosine phosphatase type IVA 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000051	None	Gadd-DA_ptp4a2_protein_levels__seqid___11699-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTK1 protein levels (SeqId = 13474-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTK1 protein levels (SeqId = 13474-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase kappa 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000051	None	Gadd-DA_gstk1_protein_levels__seqid___13474-40__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.106652	0.0212281	0.0000005118125	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	PLCB1 protein levels (SeqId = 11354-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLCB1 protein levels (SeqId = 11354-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000052	None	Gadd-DA_plcb1_protein_levels__seqid___11354-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UFD1L protein levels (SeqId = 17411-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UFD1L protein levels (SeqId = 17411-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin recognition factor in ER-associated degradation protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000052	None	Gadd-DA_ufd1l_protein_levels__seqid___17411-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK3 protein levels (SeqId = 2855-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK3 protein levels (SeqId = 2855-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000053	None	Gadd-DA_mapk3_protein_levels__seqid___2855-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RTN4IP1 protein levels (SeqId = 18180-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RTN4IP1 protein levels (SeqId = 18180-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Reticulon-4-interacting protein 1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000053	None	Gadd-DA_rtn4ip1_protein_levels__seqid___18180-58__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NACA protein levels (SeqId = 3854-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NACA protein levels (SeqId = 3854-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nascent polypeptide-associated complex subunit alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000053	None	Gadd-DA_naca_protein_levels__seqid___3854-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF16 protein levels (SeqId = 4393-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF16 protein levels (SeqId = 4393-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 16	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000053	None	Gadd-DA_fgf16_protein_levels__seqid___4393-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0413687	0.0082495	0.0000005374084	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PIP4K2B protein levels (SeqId = 18232-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIP4K2B protein levels (SeqId = 18232-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000054	None	Gadd-DA_pip4k2b_protein_levels__seqid___18232-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGEF1 protein levels (SeqId = 13976-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGEF1 protein levels (SeqId = 13976-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho guanine nucleotide exchange factor 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000054	None	Gadd-DA_arhgef1_protein_levels__seqid___13976-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAD23B protein levels (SeqId = 12522-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAD23B protein levels (SeqId = 12522-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UV excision repair protein RAD23 homolog B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000055	None	Gadd-DA_rad23b_protein_levels__seqid___12522-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VTA1 protein levels (SeqId = 4209-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VTA1 protein levels (SeqId = 4209-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vacuolar protein sorting-associated protein VTA1 homolog	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000055	None	Gadd-DA_vta1_protein_levels__seqid___4209-60__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	-0.00343	0.00066	0.00000055	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	DNM2 protein levels (SeqId = 11572-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNM2 protein levels (SeqId = 11572-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dynamin-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000056	None	Gadd-DA_dnm2_protein_levels__seqid___11572-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0450544	0.00900746	0.0000005742535	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.049	0.00985	0.00000058	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	SMAD2 protein levels (SeqId = 10364-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMAD2 protein levels (SeqId = 10364-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mothers against decapentaplegic homolog 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000058	None	Gadd-DA_smad2_protein_levels__seqid___10364-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RGS10 protein levels (SeqId = 11634-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RGS10 protein levels (SeqId = 11634-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Regulator of G-protein signaling 10	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000058	None	Gadd-DA_rgs10_protein_levels__seqid___11634-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GSK3A protein levels (SeqId = 3441-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSK3A protein levels (SeqId = 3441-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycogen synthase kinase-3 alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000058	None	Gadd-DA_gsk3a_protein_levels__seqid___3441-64__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK14 protein levels (SeqId = 5007-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK14 protein levels (SeqId = 5007-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 14	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000059	None	Gadd-DA_mapk14_protein_levels__seqid___5007-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TTC1 protein levels (SeqId = 9864-38)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TTC1 protein levels (SeqId = 9864-38)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tetratricopeptide repeat protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.0000006	None	Gadd-DA_ttc1_protein_levels__seqid___9864-38__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF4B protein levels (SeqId = 14675-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF4B protein levels (SeqId = 14675-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 4B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.0000006	None	Gadd-DA_eif4b_protein_levels__seqid___14675-20__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg06229455	chr7:157189721	7	157189721	DNAJB6	North shelf	1.398261	0.2803	0.000000609	-	27105112_hiv_infection_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	HSPE1 protein levels (SeqId = 17150-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSPE1 protein levels (SeqId = 17150-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 10 kDa heat shock protein, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.64	0.127	0.00000061	None	Gadd-DA_hspe1_protein_levels__seqid___17150-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDHX protein levels (SeqId = 18319-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDHX protein levels (SeqId = 18319-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pyruvate dehydrogenase protein X component, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000061	None	Gadd-DA_pdhx_protein_levels__seqid___18319-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.0411403	0.00824958	0.0000006203762	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	USP15 protein levels (SeqId = 19161-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	USP15 protein levels (SeqId = 19161-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin carboxyl-terminal hydrolase 15	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000063	None	Gadd-DA_usp15_protein_levels__seqid___19161-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PIN1 protein levels (SeqId = 15474-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIN1 protein levels (SeqId = 15474-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000063	None	Gadd-DA_pin1_protein_levels__seqid___15474-7__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.457658	0.0919	0.000000639	None	27105112_hiv_infection_cd4_tcells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0410918	0.0082496	0.0000006395326	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	AKT2 protein levels (SeqId = 5360-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKT2 protein levels (SeqId = 5360-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RAC-beta serine/threonine-protein kinase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000064	None	Gadd-DA_akt2_protein_levels__seqid___5360-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL2RG protein levels (SeqId = 2634-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL2RG protein levels (SeqId = 2634-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytokine receptor common subunit gamma	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000064	None	Gadd-DA_il2rg_protein_levels__seqid___2634-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPARC protein levels (SeqId = 3043-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPARC protein levels (SeqId = 3043-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SPARC	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000064	None	Gadd-DA_sparc_protein_levels__seqid___3043-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.0410759	0.0082496	0.0000006459588	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	KPNA6 protein levels (SeqId = 13969-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KPNA6 protein levels (SeqId = 13969-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Importin subunit alpha-7	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000065	None	Gadd-DA_kpna6_protein_levels__seqid___13969-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADRBK1 protein levels (SeqId = 3347-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADRBK1 protein levels (SeqId = 3347-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-adrenergic receptor kinase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000065	None	Gadd-DA_adrbk1_protein_levels__seqid___3347-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0410452	0.00824961	0.0000006584775	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	DRG1 protein levels (SeqId = 17849-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DRG1 protein levels (SeqId = 17849-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Developmentally-regulated GTP-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000066	None	Gadd-DA_drg1_protein_levels__seqid___17849-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZADH2 protein levels (SeqId = 17345-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZADH2 protein levels (SeqId = 17345-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prostaglandin reductase 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.632	0.127	0.00000067	None	Gadd-DA_zadh2_protein_levels__seqid___17345-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IST1 protein levels (SeqId = 12434-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IST1 protein levels (SeqId = 12434-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: IST1 homolog	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000067	None	Gadd-DA_ist1_protein_levels__seqid___12434-25__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0410133	0.00824962	0.0000006717631	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NME2 protein levels (SeqId = 4249-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NME2 protein levels (SeqId = 4249-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nucleoside diphosphate kinase B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000068	None	Gadd-DA_nme2_protein_levels__seqid___4249-64__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IRF3 protein levels (SeqId = 17151-84)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IRF3 protein levels (SeqId = 17151-84)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon regulatory factor 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000069	None	Gadd-DA_irf3_protein_levels__seqid___17151-84__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FKBP3 protein levels (SeqId = 18383-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FKBP3 protein levels (SeqId = 18383-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase FKBP3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.0000007	None	Gadd-DA_fkbp3_protein_levels__seqid___18383-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLIC4 protein levels (SeqId = 15314-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLIC4 protein levels (SeqId = 15314-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chloride intracellular channel protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000071	None	Gadd-DA_clic4_protein_levels__seqid___15314-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MYCBP protein levels (SeqId = 19250-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYCBP protein levels (SeqId = 19250-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: c-Myc-binding protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000071	None	Gadd-DA_mycbp_protein_levels__seqid___19250-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2F protein levels (SeqId = 18213-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2F protein levels (SeqId = 18213-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NEDD8-conjugating enzyme UBE2F	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000071	None	Gadd-DA_ube2f_protein_levels__seqid___18213-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HARS protein levels (SeqId = 17450-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HARS protein levels (SeqId = 17450-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histidine--tRNA ligase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000072	None	Gadd-DA_hars_protein_levels__seqid___17450-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DTD2 protein levels (SeqId = 18280-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DTD2 protein levels (SeqId = 18280-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: D-aminoacyl-tRNA deacylase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000072	None	Gadd-DA_dtd2_protein_levels__seqid___18280-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAT6 protein levels (SeqId = 10372-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAT6 protein levels (SeqId = 10372-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal transducer and activator of transcription 6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.629	0.127	0.00000073	None	Gadd-DA_stat6_protein_levels__seqid___10372-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TOLLIP protein levels (SeqId = 13963-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TOLLIP protein levels (SeqId = 13963-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Toll-interacting protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000073	None	Gadd-DA_tollip_protein_levels__seqid___13963-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TSG101 protein levels (SeqId = 13044-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TSG101 protein levels (SeqId = 13044-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor susceptibility gene 101 protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000073	None	Gadd-DA_tsg101_protein_levels__seqid___13044-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.040867	0.00824967	0.0000007360145	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM150B protein levels (SeqId = 6284-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM150B protein levels (SeqId = 6284-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ALK and LTK ligand 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000074	None	Gadd-DA_fam150b_protein_levels__seqid___6284-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ISG15 protein levels (SeqId = 14151-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISG15 protein levels (SeqId = 14151-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-like protein ISG15	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000074	None	Gadd-DA_isg15_protein_levels__seqid___14151-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAP2K1 protein levels (SeqId = 2864-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAP2K1 protein levels (SeqId = 2864-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dual specificity mitogen-activated protein kinase kinase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000074	None	Gadd-DA_map2k1_protein_levels__seqid___2864-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	0.0503043	0.0101589	0.000000743689	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	VPS24 protein levels (SeqId = 12508-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VPS24 protein levels (SeqId = 12508-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Charged multivesicular body protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000075	None	Gadd-DA_vps24_protein_levels__seqid___12508-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PCNP protein levels (SeqId = 17769-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PCNP protein levels (SeqId = 17769-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PEST proteolytic signal-containing nuclear protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000076	None	Gadd-DA_pcnp_protein_levels__seqid___17769-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPRE2 protein levels (SeqId = 16856-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPRE2 protein levels (SeqId = 16856-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Microtubule-associated protein RP/EB family member 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000076	None	Gadd-DA_mapre2_protein_levels__seqid___16856-79__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMA6 protein levels (SeqId = 3860-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMA6 protein levels (SeqId = 3860-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteasome subunit alpha type-6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000077	None	Gadd-DA_psma6_protein_levels__seqid___3860-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	G3BP1 protein levels (SeqId = 19266-35)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	G3BP1 protein levels (SeqId = 19266-35)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras GTPase-activating protein-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000077	None	Gadd-DA_g3bp1_protein_levels__seqid___19266-35__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0407841	0.0082497	0.000000774995	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0407793	0.0082497	0.0000007772989	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FAHD1 protein levels (SeqId = 17819-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAHD1 protein levels (SeqId = 17819-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acylpyruvase FAHD1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000078	None	Gadd-DA_fahd1_protein_levels__seqid___17819-30__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.0417778	0.00845523	0.0000007855758	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CLEC1B protein levels (SeqId = 4332-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLEC1B protein levels (SeqId = 4332-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-type lectin domain family 1 member B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000079	None	Gadd-DA_clec1b_protein_levels__seqid___4332-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BAD protein levels (SeqId = 5870-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BAD protein levels (SeqId = 5870-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bcl2-associated agonist of cell death	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000079	None	Gadd-DA_bad_protein_levels__seqid___5870-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PABPC3 protein levels (SeqId = 10447-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PABPC3 protein levels (SeqId = 10447-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Polyadenylate-binding protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000079	None	Gadd-DA_pabpc3_protein_levels__seqid___10447-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TXNDC12 protein levels (SeqId = 19334-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXNDC12 protein levels (SeqId = 19334-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin domain-containing protein 12	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000079	None	Gadd-DA_txndc12_protein_levels__seqid___19334-62__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PABPC4 protein levels (SeqId = 12603-87)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PABPC4 protein levels (SeqId = 12603-87)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Polyadenylate-binding protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.0000008	None	Gadd-DA_pabpc4_protein_levels__seqid___12603-87__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PURA protein levels (SeqId = 12537-88)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PURA protein levels (SeqId = 12537-88)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcriptional activator protein Pur-alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.0000008	None	Gadd-DA_pura_protein_levels__seqid___12537-88__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.040724	0.00824972	0.0000008044775	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ELAVL1 protein levels (SeqId = 11592-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ELAVL1 protein levels (SeqId = 11592-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ELAV-like protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000081	None	Gadd-DA_elavl1_protein_levels__seqid___11592-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TARS protein levels (SeqId = 18186-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TARS protein levels (SeqId = 18186-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Threonine--tRNA ligase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000081	None	Gadd-DA_tars_protein_levels__seqid___18186-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TIRAP protein levels (SeqId = 9839-148)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TIRAP protein levels (SeqId = 9839-148)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Toll/interleukin-1 receptor domain-containing adapter protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000084	None	Gadd-DA_tirap_protein_levels__seqid___9839-148__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SMAD3 protein levels (SeqId = 10363-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMAD3 protein levels (SeqId = 10363-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mothers against decapentaplegic homolog 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000084	None	Gadd-DA_smad3_protein_levels__seqid___10363-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TSSC4 protein levels (SeqId = 18181-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TSSC4 protein levels (SeqId = 18181-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein TSSC4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000084	None	Gadd-DA_tssc4_protein_levels__seqid___18181-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0406505	0.00824975	0.0000008420538	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.36985	0.0750656	0.0000008426159	None	39706196_Hannah-M.-Smith_bmi_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	PDCD5 protein levels (SeqId = 12517-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDCD5 protein levels (SeqId = 12517-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Programmed cell death protein 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000085	None	Gadd-DA_pdcd5_protein_levels__seqid___12517-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRDM4 protein levels (SeqId = 12779-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRDM4 protein levels (SeqId = 12779-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PR domain zinc finger protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000085	None	Gadd-DA_prdm4_protein_levels__seqid___12779-30__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0441405	0.00896673	0.0000008628803	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	0.0406081	0.00824976	0.000000864485	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PPIH protein levels (SeqId = 12449-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPIH protein levels (SeqId = 12449-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase H	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000087	None	Gadd-DA_ppih_protein_levels__seqid___12449-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF7 protein levels (SeqId = 4487-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF7 protein levels (SeqId = 4487-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 7	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.00000087	None	Gadd-DA_fgf7_protein_levels__seqid___4487-1__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01469549	chr7:157129690	7	157129690	DNAJB6	Island	0.00036	0.000073	0.00000088	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12690313	chr7:157129430	7	157129430	DNAJB6	Island	0.00029	0.000059	0.00000088	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg25039694	chr7:157192974	7	157192974	DNAJB6	Island	0.0296	0.00582	0.00000088	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2L3 protein levels (SeqId = 3874-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2L3 protein levels (SeqId = 3874-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 L3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000088	None	Gadd-DA_ube2l3_protein_levels__seqid___3874-8__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0443488	0.00901943	0.0000008881636	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0405569	0.00824978	0.000000892335	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ANXA7 protein levels (SeqId = 18244-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANXA7 protein levels (SeqId = 18244-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Annexin A7	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.63	0.127	0.0000009	None	Gadd-DA_anxa7_protein_levels__seqid___18244-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NUDT2 protein levels (SeqId = 16583-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUDT2 protein levels (SeqId = 16583-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000009	None	Gadd-DA_nudt2_protein_levels__seqid___16583-8__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0440967	0.00897513	0.0000009056475	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0421674	0.00858538	0.0000009134002	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-1	0.212	0.00000095	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	KARS protein levels (SeqId = 19249-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KARS protein levels (SeqId = 19249-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lysine--tRNA ligase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000095	None	Gadd-DA_kars_protein_levels__seqid___19249-18__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0404345	0.00824982	0.000000962415	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0404222	0.00824982	0.0000009697783	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TACO1 protein levels (SeqId = 9257-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TACO1 protein levels (SeqId = 9257-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Translational activator of cytochrome c oxidase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000097	None	Gadd-DA_taco1_protein_levels__seqid___9257-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SLC30A5 protein levels (SeqId = 9594-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SLC30A5 protein levels (SeqId = 9594-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Zinc transporter 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000097	None	Gadd-DA_slc30a5_protein_levels__seqid___9594-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KIAA1279 protein levels (SeqId = 12956-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIAA1279 protein levels (SeqId = 12956-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: KIF1-binding protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000097	None	Gadd-DA_kiaa1279_protein_levels__seqid___12956-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NHEJ1 protein levels (SeqId = 11351-233)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NHEJ1 protein levels (SeqId = 11351-233)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Non-homologous end-joining factor 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000097	None	Gadd-DA_nhej1_protein_levels__seqid___11351-233__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EEF1D protein levels (SeqId = 17826-341)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EEF1D protein levels (SeqId = 17826-341)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Elongation factor 1-delta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000098	None	Gadd-DA_eef1d_protein_levels__seqid___17826-341__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDH2 protein levels (SeqId = 15534-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDH2 protein levels (SeqId = 15534-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Malate dehydrogenase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000098	None	Gadd-DA_mdh2_protein_levels__seqid___15534-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NCK2 protein levels (SeqId = 13615-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NCK2 protein levels (SeqId = 13615-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytoplasmic protein NCK2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000098	None	Gadd-DA_nck2_protein_levels__seqid___13615-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPRE1 protein levels (SeqId = 12469-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPRE1 protein levels (SeqId = 12469-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Microtubule-associated protein RP/EB family member 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000099	None	Gadd-DA_mapre1_protein_levels__seqid___12469-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CIRBP protein levels (SeqId = 12724-81)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CIRBP protein levels (SeqId = 12724-81)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cold-inducible RNA-binding protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.00000099	None	Gadd-DA_cirbp_protein_levels__seqid___12724-81__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0403821	0.00824984	0.0000009940399	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20603964	chr7:157195543	7	157195543	DNAJB6	South shelf	0.0014	None	0.000001	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20603964	chr7:157195543	7	157195543	DNAJB6	South shelf	0.0004	None	0.000001	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	GPI protein levels (SeqId = 4272-46)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GPI protein levels (SeqId = 4272-46)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glucose-6-phosphate isomerase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.000001	None	Gadd-DA_gpi_protein_levels__seqid___4272-46__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK10 protein levels (SeqId = 15418-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK10 protein levels (SeqId = 15418-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 10	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.000001	None	Gadd-DA_mapk10_protein_levels__seqid___15418-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NIT2 protein levels (SeqId = 17808-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NIT2 protein levels (SeqId = 17808-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Omega-amidase NIT2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.000001	None	Gadd-DA_nit2_protein_levels__seqid___17808-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SKIL protein levels (SeqId = 14670-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SKIL protein levels (SeqId = 14670-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ski-like protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.000001	None	Gadd-DA_skil_protein_levels__seqid___14670-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SRC protein levels (SeqId = 15433-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SRC protein levels (SeqId = 15433-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proto-oncogene tyrosine-protein kinase Src	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.000001	None	Gadd-DA_src_protein_levels__seqid___15433-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UFM1 protein levels (SeqId = 3836-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UFM1 protein levels (SeqId = 3836-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-fold modifier 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.000001	None	Gadd-DA_ufm1_protein_levels__seqid___3836-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BDNF protein levels (SeqId = 2421-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BDNF protein levels (SeqId = 2421-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Brain-derived neurotrophic factor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.621	0.127	0.000001	None	Gadd-DA_bdnf_protein_levels__seqid___2421-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NMT1 protein levels (SeqId = 5196-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NMT1 protein levels (SeqId = 5196-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycylpeptide N-tetradecanoyltransferase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.000001	None	Gadd-DA_nmt1_protein_levels__seqid___5196-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCDC50 protein levels (SeqId = 12399-194)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCDC50 protein levels (SeqId = 12399-194)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coiled-coil domain-containing protein 50	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.622	0.127	0.000001	None	Gadd-DA_ccdc50_protein_levels__seqid___12399-194__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DEF6 protein levels (SeqId = 14090-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DEF6 protein levels (SeqId = 14090-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Differentially expressed in FDCP 6 homolog	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.000001	None	Gadd-DA_def6_protein_levels__seqid___14090-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXDC2 protein levels (SeqId = 11342-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXDC2 protein levels (SeqId = 11342-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.000001	None	Gadd-DA_plxdc2_protein_levels__seqid___11342-59__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05726556	chr7:157203124	7	157203124	DNAJB6	Island	0.193631	0.0396766	0.000001069125	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0535974	0.0109837	0.00000107364	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0402438	0.00824988	0.000001082353	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.18	0.0364	0.0000011	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	0.0044	None	0.0000011	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	S100A5 protein levels (SeqId = 15303-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	S100A5 protein levels (SeqId = 15303-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein S100-A5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000011	None	Gadd-DA_s100a5_protein_levels__seqid___15303-63__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FLRT1 protein levels (SeqId = 4547-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FLRT1 protein levels (SeqId = 4547-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leucine-rich repeat transmembrane protein FLRT1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000011	None	Gadd-DA_flrt1_protein_levels__seqid___4547-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDE5A protein levels (SeqId = 5256-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDE5A protein levels (SeqId = 5256-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: cGMP-specific 3',5'-cyclic phosphodiesterase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000011	None	Gadd-DA_pde5a_protein_levels__seqid___5256-86__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKCI protein levels (SeqId = 3379-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKCI protein levels (SeqId = 3379-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein kinase C iota type	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000011	None	Gadd-DA_prkci_protein_levels__seqid___3379-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AIDA protein levels (SeqId = 17347-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AIDA protein levels (SeqId = 17347-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Axin interactor, dorsalization-associated protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000011	None	Gadd-DA_aida_protein_levels__seqid___17347-80__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKCB protein levels (SeqId = 5475-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKCB protein levels (SeqId = 5475-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein kinase C beta type	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000011	None	Gadd-DA_prkcb_protein_levels__seqid___5475-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP2R5A protein levels (SeqId = 13622-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP2R5A protein levels (SeqId = 13622-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000011	None	Gadd-DA_ppp2r5a_protein_levels__seqid___13622-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAFAH1B2 protein levels (SeqId = 2642-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAFAH1B2 protein levels (SeqId = 2642-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet-activating factor acetylhydrolase IB subunit beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000011	None	Gadd-DA_pafah1b2_protein_levels__seqid___2642-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	0.0402142	0.00824989	0.000001102176	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0538664	0.0110596	0.000001124376	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0401767	0.00824991	0.000001127852	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.040176	0.00824991	0.000001128356	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0401591	0.00824991	0.000001140112	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0401496	0.00824991	0.00000114672	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	0.0479732	0.00985822	0.000001148813	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0537405	0.0110465	0.000001156762	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0436837	0.00897958	0.00000115777	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0401226	0.00824992	0.000001165901	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0400767	0.00824994	0.000001199105	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg03996020	chr7:157180124	7	157180124	DNAJB6	Open sea	-0.00696	0.00143	0.0000012	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	AGFG1 protein levels (SeqId = 11681-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AGFG1 protein levels (SeqId = 11681-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Arf-GAP domain and FG repeat-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_agfg1_protein_levels__seqid___11681-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CA13 protein levels (SeqId = 3420-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CA13 protein levels (SeqId = 3420-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carbonic anhydrase 13	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_ca13_protein_levels__seqid___3420-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BDNF protein levels (SeqId = 14047-78)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BDNF protein levels (SeqId = 14047-78)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Brain-derived neurotrophic factor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_bdnf_protein_levels__seqid___14047-78__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PKM2 protein levels (SeqId = 4240-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PKM2 protein levels (SeqId = 4240-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pyruvate kinase PKM	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_pkm2_protein_levels__seqid___4240-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CAB39 protein levels (SeqId = 17757-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAB39 protein levels (SeqId = 17757-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium-binding protein 39	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_cab39_protein_levels__seqid___17757-86__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AREG protein levels (SeqId = 2970-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AREG protein levels (SeqId = 2970-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Amphiregulin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_areg_protein_levels__seqid___2970-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TWF1 protein levels (SeqId = 12871-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TWF1 protein levels (SeqId = 12871-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Twinfilin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_twf1_protein_levels__seqid___12871-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DPP7 protein levels (SeqId = 8346-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPP7 protein levels (SeqId = 8346-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dipeptidyl peptidase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.616	0.127	0.0000012	None	Gadd-DA_dpp7_protein_levels__seqid___8346-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF3G protein levels (SeqId = 11454-87)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF3G protein levels (SeqId = 11454-87)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 3 subunit G	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_eif3g_protein_levels__seqid___11454-87__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTP1 protein levels (SeqId = 4911-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTP1 protein levels (SeqId = 4911-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase P	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_gstp1_protein_levels__seqid___4911-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AASDHPPT protein levels (SeqId = 17320-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AASDHPPT protein levels (SeqId = 17320-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_aasdhppt_protein_levels__seqid___17320-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EPS15L1 protein levels (SeqId = 4212-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPS15L1 protein levels (SeqId = 4212-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Epidermal growth factor receptor substrate 15-like 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000012	None	Gadd-DA_eps15l1_protein_levels__seqid___4212-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0473547	0.0097512	0.000001208376	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0400226	0.00824996	0.000001239496	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	-0.0399883	0.00824997	0.000001265735	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.84135	0.1738	0.00000128	-	27105112_hiv_infection_neutrophils
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01766193	chr7:157202248	7	157202248	DNAJB6	North shore	0.0012	0.00024	0.0000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24815507	chr7:157198482	7	157198482	DNAJB6	North shelf	0.00077	None	0.0000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	HDHD2 protein levels (SeqId = 13472-35)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDHD2 protein levels (SeqId = 13472-35)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Haloacid dehalogenase-like hydrolase domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000013	None	Gadd-DA_hdhd2_protein_levels__seqid___13472-35__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CHMP2A protein levels (SeqId = 17728-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHMP2A protein levels (SeqId = 17728-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Charged multivesicular body protein 2a	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000013	None	Gadd-DA_chmp2a_protein_levels__seqid___17728-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACYP2 protein levels (SeqId = 12812-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACYP2 protein levels (SeqId = 12812-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acylphosphatase-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000013	None	Gadd-DA_acyp2_protein_levels__seqid___12812-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GABARAPL2 protein levels (SeqId = 12494-99)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GABARAPL2 protein levels (SeqId = 12494-99)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-aminobutyric acid receptor-associated protein-like 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000013	None	Gadd-DA_gabarapl2_protein_levels__seqid___12494-99__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB3D protein levels (SeqId = 19379-154)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB3D protein levels (SeqId = 19379-154)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-3D	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000013	None	Gadd-DA_rab3d_protein_levels__seqid___19379-154__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBQLN4 protein levels (SeqId = 12720-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBQLN4 protein levels (SeqId = 12720-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquilin-4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000013	None	Gadd-DA_ubqln4_protein_levels__seqid___12720-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CD68 protein levels (SeqId = 18922-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD68 protein levels (SeqId = 18922-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Macrosialin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.614	0.127	0.0000013	None	Gadd-DA_cd68_protein_levels__seqid___18922-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RANBP1 protein levels (SeqId = 18191-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RANBP1 protein levels (SeqId = 18191-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ran-specific GTPase-activating protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000013	None	Gadd-DA_ranbp1_protein_levels__seqid___18191-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAFG protein levels (SeqId = 19281-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAFG protein levels (SeqId = 19281-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription factor MafG	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000013	None	Gadd-DA_mafg_protein_levels__seqid___19281-86__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAD23A protein levels (SeqId = 10058-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAD23A protein levels (SeqId = 10058-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UV excision repair protein RAD23 homolog A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000013	None	Gadd-DA_rad23a_protein_levels__seqid___10058-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP3CA protein levels (SeqId = 4903-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP3CA protein levels (SeqId = 4903-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcineurin subunit B type 1|Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000013	None	Gadd-DA_ppp3ca_protein_levels__seqid___4903-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GUK1 protein levels (SeqId = 17325-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GUK1 protein levels (SeqId = 17325-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Guanylate kinase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000013	None	Gadd-DA_guk1_protein_levels__seqid___17325-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGAP5 protein levels (SeqId = 14748-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGAP5 protein levels (SeqId = 14748-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000013	None	Gadd-DA_arhgap5_protein_levels__seqid___14748-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLEK protein levels (SeqId = 7875-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLEK protein levels (SeqId = 7875-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pleckstrin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000013	None	Gadd-DA_plek_protein_levels__seqid___7875-86__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.0398929	0.00825	0.000001341532	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0398738	0.00825001	0.000001357221	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0398257	0.00825002	0.000001397563	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-1.5	0.304	0.0000014	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	CNP protein levels (SeqId = 6609-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CNP protein levels (SeqId = 6609-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 2',3'-cyclic-nucleotide 3'-phosphodiesterase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000014	None	Gadd-DA_cnp_protein_levels__seqid___6609-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	YWHAB protein levels (SeqId = 14156-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YWHAB protein levels (SeqId = 14156-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 14-3-3 protein beta/alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000014	None	Gadd-DA_ywhab_protein_levels__seqid___14156-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PGK1 protein levels (SeqId = 5020-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGK1 protein levels (SeqId = 5020-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphoglycerate kinase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000014	None	Gadd-DA_pgk1_protein_levels__seqid___5020-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APRT protein levels (SeqId = 10088-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APRT protein levels (SeqId = 10088-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adenine phosphoribosyltransferase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000014	None	Gadd-DA_aprt_protein_levels__seqid___10088-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BCAT2 protein levels (SeqId = 19365-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BCAT2 protein levels (SeqId = 19365-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Branched-chain-amino-acid aminotransferase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000014	None	Gadd-DA_bcat2_protein_levels__seqid___19365-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2V2 protein levels (SeqId = 18165-181)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2V2 protein levels (SeqId = 18165-181)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 variant 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000014	None	Gadd-DA_ube2v2_protein_levels__seqid___18165-181__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKAA2 protein levels (SeqId = 5245-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKAA2 protein levels (SeqId = 5245-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 5'-AMP-activated protein kinase subunit beta-2|5'-AMP-activated protein kinase catalytic subunit alpha-2|5'-AMP-activated protein kinase subunit gamma-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000014	None	Gadd-DA_prkaa2_protein_levels__seqid___5245-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MLEC protein levels (SeqId = 6285-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MLEC protein levels (SeqId = 6285-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Malectin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000014	None	Gadd-DA_mlec_protein_levels__seqid___6285-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RHOA protein levels (SeqId = 9855-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RHOA protein levels (SeqId = 9855-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transforming protein RhoA	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000014	None	Gadd-DA_rhoa_protein_levels__seqid___9855-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2K protein levels (SeqId = 17380-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2K protein levels (SeqId = 17380-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 K	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.62	0.127	0.0000014	None	Gadd-DA_ube2k_protein_levels__seqid___17380-2__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.285324	0.059201	0.000001450821	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0526457	0.0109279	0.000001467829	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PGM2 protein levels (SeqId = 18330-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGM2 protein levels (SeqId = 18330-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphoglucomutase-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000015	None	Gadd-DA_pgm2_protein_levels__seqid___18330-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KLK15 protein levels (SeqId = 6491-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLK15 protein levels (SeqId = 6491-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kallikrein-15	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000015	None	Gadd-DA_klk15_protein_levels__seqid___6491-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UGT2A1 protein levels (SeqId = 8907-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UGT2A1 protein levels (SeqId = 8907-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UDP-glucuronosyltransferase 2A1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000015	None	Gadd-DA_ugt2a1_protein_levels__seqid___8907-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGDIB protein levels (SeqId = 9846-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGDIB protein levels (SeqId = 9846-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GDP-dissociation inhibitor 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000015	None	Gadd-DA_arhgdib_protein_levels__seqid___9846-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHC1 protein levels (SeqId = 16043-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHC1 protein levels (SeqId = 16043-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SHC-transforming protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000015	None	Gadd-DA_shc1_protein_levels__seqid___16043-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB14 protein levels (SeqId = 14283-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB14 protein levels (SeqId = 14283-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-14	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.613	0.127	0.0000015	None	Gadd-DA_rab14_protein_levels__seqid___14283-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDX6 protein levels (SeqId = 12869-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDX6 protein levels (SeqId = 12869-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable ATP-dependent RNA helicase DDX6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000015	None	Gadd-DA_ddx6_protein_levels__seqid___12869-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARFIP1 protein levels (SeqId = 13488-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARFIP1 protein levels (SeqId = 13488-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Arfaptin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000015	None	Gadd-DA_arfip1_protein_levels__seqid___13488-3__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.02	0.00407	0.0000015	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0396905	0.00825007	0.000001517183	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0396583	0.00825008	0.000001547105	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0470096	0.00977964	0.000001548169	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0444339	0.00925136	0.000001578797	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg19858151	chr7:157200669	7	157200669	DNAJB6	North shore	1.032065	0.2151	0.0000016	-	27105112_hiv_infection_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	N6AMT1 protein levels (SeqId = 11096-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	N6AMT1 protein levels (SeqId = 11096-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Methyltransferase N6AMT1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000016	None	Gadd-DA_n6amt1_protein_levels__seqid___11096-57__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NSFL1C protein levels (SeqId = 4250-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NSFL1C protein levels (SeqId = 4250-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NSFL1 cofactor p47	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.607	0.127	0.0000016	None	Gadd-DA_nsfl1c_protein_levels__seqid___4250-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CBL protein levels (SeqId = 12016-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBL protein levels (SeqId = 12016-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase CBL	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000016	None	Gadd-DA_cbl_protein_levels__seqid___12016-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPBP protein levels (SeqId = 16765-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPBP protein levels (SeqId = 16765-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet basic protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000016	None	Gadd-DA_ppbp_protein_levels__seqid___16765-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CRKL protein levels (SeqId = 9877-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRKL protein levels (SeqId = 9877-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Crk-like protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000016	None	Gadd-DA_crkl_protein_levels__seqid___9877-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRDX6 protein levels (SeqId = 5018-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRDX6 protein levels (SeqId = 5018-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxiredoxin-6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000016	None	Gadd-DA_prdx6_protein_levels__seqid___5018-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MESDC2 protein levels (SeqId = 15299-102)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MESDC2 protein levels (SeqId = 15299-102)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: LRP chaperone MESD	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000016	None	Gadd-DA_mesdc2_protein_levels__seqid___15299-102__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBQLN2 protein levels (SeqId = 19121-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBQLN2 protein levels (SeqId = 19121-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquilin-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000016	None	Gadd-DA_ubqln2_protein_levels__seqid___19121-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0395904	0.0082501	0.00000161209	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.040435	0.00842702	0.000001616273	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25039694	chr7:157192974	7	157192974	DNAJB6	Island	0.0395796	0.0082501	0.000001622667	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg26668151	chr7:157180005	7	157180005	DNAJB6	Open sea	-1.124619	0.2347	0.00000166	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0429059	0.00895452	0.000001671276	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0510294	0.0106506	0.000001673896	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	0.0395265	0.00825012	0.0000016756	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.034	0.00713	0.0000017	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	PNKP protein levels (SeqId = 13657-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PNKP protein levels (SeqId = 13657-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bifunctional polynucleotide phosphatase/kinase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000017	None	Gadd-DA_pnkp_protein_levels__seqid___13657-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPG20 protein levels (SeqId = 11161-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPG20 protein levels (SeqId = 11161-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Spartin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000017	None	Gadd-DA_spg20_protein_levels__seqid___11161-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DOK2 protein levels (SeqId = 19578-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DOK2 protein levels (SeqId = 19578-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Docking protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000017	None	Gadd-DA_dok2_protein_levels__seqid___19578-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VPS26A protein levels (SeqId = 19293-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VPS26A protein levels (SeqId = 19293-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vacuolar protein sorting-associated protein 26A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000017	None	Gadd-DA_vps26a_protein_levels__seqid___19293-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CBX3 protein levels (SeqId = 18868-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBX3 protein levels (SeqId = 18868-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chromobox protein homolog 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000017	None	Gadd-DA_cbx3_protein_levels__seqid___18868-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB32 protein levels (SeqId = 17778-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB32 protein levels (SeqId = 17778-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-32	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000017	None	Gadd-DA_rab32_protein_levels__seqid___17778-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDOST protein levels (SeqId = 17161-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDOST protein levels (SeqId = 17161-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000017	None	Gadd-DA_ddost_protein_levels__seqid___17161-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IDH3G protein levels (SeqId = 19275-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IDH3G protein levels (SeqId = 19275-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000017	None	Gadd-DA_idh3g_protein_levels__seqid___19275-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NUDCD3 protein levels (SeqId = 4254-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUDCD3 protein levels (SeqId = 4254-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NudC domain-containing protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000017	None	Gadd-DA_nudcd3_protein_levels__seqid___4254-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDE5A protein levels (SeqId = 16805-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDE5A protein levels (SeqId = 16805-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: cGMP-specific 3',5'-cyclic phosphodiesterase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000017	None	Gadd-DA_pde5a_protein_levels__seqid___16805-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0526066	0.0110076	0.00000177761	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17529436	chr7:157201728	7	157201728	DNAJB6	North shore	0.00075	None	0.0000018	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	GDI1 protein levels (SeqId = 16810-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GDI1 protein levels (SeqId = 16810-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rab GDP dissociation inhibitor alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000018	None	Gadd-DA_gdi1_protein_levels__seqid___16810-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBASH3B protein levels (SeqId = 12558-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBASH3B protein levels (SeqId = 12558-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-associated and SH3 domain-containing protein B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000018	None	Gadd-DA_ubash3b_protein_levels__seqid___12558-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CACYBP protein levels (SeqId = 12432-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CACYBP protein levels (SeqId = 12432-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcyclin-binding protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000018	None	Gadd-DA_cacybp_protein_levels__seqid___12432-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRPSAP2 protein levels (SeqId = 19150-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRPSAP2 protein levels (SeqId = 19150-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphoribosyl pyrophosphate synthase-associated protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000018	None	Gadd-DA_prpsap2_protein_levels__seqid___19150-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPBP protein levels (SeqId = 2790-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPBP protein levels (SeqId = 2790-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet basic protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000018	None	Gadd-DA_ppbp_protein_levels__seqid___2790-54__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DUT protein levels (SeqId = 9995-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DUT protein levels (SeqId = 9995-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000018	None	Gadd-DA_dut_protein_levels__seqid___9995-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APP protein levels (SeqId = 3171-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APP protein levels (SeqId = 3171-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Amyloid-beta precursor protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000018	None	Gadd-DA_app_protein_levels__seqid___3171-57__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CROT protein levels (SeqId = 13929-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CROT protein levels (SeqId = 13929-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxisomal carnitine O-octanoyltransferase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.126	0.0000018	None	Gadd-DA_crot_protein_levels__seqid___13929-27__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26668151	chr7:157180005	7	157180005	DNAJB6	Open sea	-0.01529	0.0031	0.0000018	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0458309	0.00959846	0.000001816108	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0523036	0.0109704	0.000001881218	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.04	0.00839	0.0000019	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ITSN1 protein levels (SeqId = 14070-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ITSN1 protein levels (SeqId = 14070-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Intersectin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000019	None	Gadd-DA_itsn1_protein_levels__seqid___14070-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PARK7 protein levels (SeqId = 19523-215)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PARK7 protein levels (SeqId = 19523-215)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein/nucleic acid deglycase DJ-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000019	None	Gadd-DA_park7_protein_levels__seqid___19523-215__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2V1 protein levels (SeqId = 11626-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2V1 protein levels (SeqId = 11626-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 variant 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000019	None	Gadd-DA_ube2v1_protein_levels__seqid___11626-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GNPNAT1 protein levels (SeqId = 13954-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GNPNAT1 protein levels (SeqId = 13954-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glucosamine 6-phosphate N-acetyltransferase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000019	None	Gadd-DA_gnpnat1_protein_levels__seqid___13954-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SBDS protein levels (SeqId = 3866-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SBDS protein levels (SeqId = 3866-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribosome maturation protein SBDS	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000019	None	Gadd-DA_sbds_protein_levels__seqid___3866-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TAF15 protein levels (SeqId = 16865-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TAF15 protein levels (SeqId = 16865-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: TATA-binding protein-associated factor 2N	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000019	None	Gadd-DA_taf15_protein_levels__seqid___16865-62__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACTN1 protein levels (SeqId = 9843-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACTN1 protein levels (SeqId = 9843-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-actinin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000019	None	Gadd-DA_actn1_protein_levels__seqid___9843-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAC3 protein levels (SeqId = 16769-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAC3 protein levels (SeqId = 16769-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related C3 botulinum toxin substrate 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000019	None	Gadd-DA_rac3_protein_levels__seqid___16769-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRPEL1 protein levels (SeqId = 7113-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRPEL1 protein levels (SeqId = 7113-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GrpE protein homolog 1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000019	None	Gadd-DA_grpel1_protein_levels__seqid___7113-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRAP protein levels (SeqId = 12820-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRAP protein levels (SeqId = 12820-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GRB2-related adapter protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.0000019	None	Gadd-DA_grap_protein_levels__seqid___12820-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0509927	0.0107019	0.000001908383	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg12381188	chr7:157199595	7	157199595	DNAJB6	North shelf	0.221189	0.0464593	0.000001942741	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0461895	0.00970527	0.000001962	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0462037	0.00970847	0.000001963032	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0392516	0.00825021	0.000001977202	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	G3BP2 protein levels (SeqId = 9831-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	G3BP2 protein levels (SeqId = 9831-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras GTPase-activating protein-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.000002	None	Gadd-DA_g3bp2_protein_levels__seqid___9831-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL15 protein levels (SeqId = 19568-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL15 protein levels (SeqId = 19568-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-15	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.000002	None	Gadd-DA_il15_protein_levels__seqid___19568-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CS protein levels (SeqId = 18309-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CS protein levels (SeqId = 18309-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Citrate synthase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.000002	None	Gadd-DA_cs_protein_levels__seqid___18309-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PCBP1 protein levels (SeqId = 11458-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PCBP1 protein levels (SeqId = 11458-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Poly(rC)-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.000002	None	Gadd-DA_pcbp1_protein_levels__seqid___11458-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIRT3 protein levels (SeqId = 17495-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIRT3 protein levels (SeqId = 17495-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.000002	None	Gadd-DA_sirt3_protein_levels__seqid___17495-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAMBP protein levels (SeqId = 19187-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAMBP protein levels (SeqId = 19187-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: STAM-binding protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.61	0.127	0.000002	None	Gadd-DA_stambp_protein_levels__seqid___19187-21__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0392	0.00824492	0.000002008841	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02271119	chr7:157198869	7	157198869	DNAJB6	North shelf	-0.0391911	0.00825023	0.000002050346	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0391876	0.00825023	0.000002054582	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg14651435	chr7:157209551	7	157209551	DNAJB6	South shore	0.2006	0.0405	0.0000021	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Gadd DA	Generation Scotland	35945220	31/07/2022	PDIA6 protein levels (SeqId = 5650-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDIA6 protein levels (SeqId = 5650-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein disulfide-isomerase A6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000021	None	Gadd-DA_pdia6_protein_levels__seqid___5650-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP1CC protein levels (SeqId = 19295-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP1CC protein levels (SeqId = 19295-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000021	None	Gadd-DA_ppp1cc_protein_levels__seqid___19295-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF3J protein levels (SeqId = 13497-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF3J protein levels (SeqId = 13497-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 3 subunit J	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000021	None	Gadd-DA_eif3j_protein_levels__seqid___13497-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CTBP1 protein levels (SeqId = 11217-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CTBP1 protein levels (SeqId = 11217-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-terminal-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000021	None	Gadd-DA_ctbp1_protein_levels__seqid___11217-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BOLA3 protein levels (SeqId = 5980-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BOLA3 protein levels (SeqId = 5980-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BolA-like protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000021	None	Gadd-DA_bola3_protein_levels__seqid___5980-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPIE protein levels (SeqId = 5238-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPIE protein levels (SeqId = 5238-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase E	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000021	None	Gadd-DA_ppie_protein_levels__seqid___5238-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAK4 protein levels (SeqId = 13719-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAK4 protein levels (SeqId = 13719-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase PAK 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000021	None	Gadd-DA_pak4_protein_levels__seqid___13719-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CHMP2B protein levels (SeqId = 17350-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHMP2B protein levels (SeqId = 17350-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Charged multivesicular body protein 2b	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000021	None	Gadd-DA_chmp2b_protein_levels__seqid___17350-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RANBP3 protein levels (SeqId = 14037-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RANBP3 protein levels (SeqId = 14037-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ran-binding protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000021	None	Gadd-DA_ranbp3_protein_levels__seqid___14037-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDXP protein levels (SeqId = 3897-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDXP protein levels (SeqId = 3897-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pyridoxal phosphate phosphatase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000021	None	Gadd-DA_pdxp_protein_levels__seqid___3897-61__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0643406	0.0135647	0.000002123258	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0468685	0.0098916	0.000002176379	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0406255	0.00857479	0.00000218094	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	HMHA1 protein levels (SeqId = 13544-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HMHA1 protein levels (SeqId = 13544-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 45	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000022	None	Gadd-DA_hmha1_protein_levels__seqid___13544-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB2 protein levels (SeqId = 11438-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB2 protein levels (SeqId = 11438-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000022	None	Gadd-DA_dnajb2_protein_levels__seqid___11438-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANP32B protein levels (SeqId = 4194-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANP32B protein levels (SeqId = 4194-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acidic leucine-rich nuclear phosphoprotein 32 family member B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000022	None	Gadd-DA_anp32b_protein_levels__seqid___4194-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GP6 protein levels (SeqId = 3194-36)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GP6 protein levels (SeqId = 3194-36)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet glycoprotein VI	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000022	None	Gadd-DA_gp6_protein_levels__seqid___3194-36__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CAPN1 protein levels (SeqId = 2668-70)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAPN1 protein levels (SeqId = 2668-70)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calpain-1 catalytic subunit|Calpain small subunit 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000022	None	Gadd-DA_capn1_protein_levels__seqid___2668-70__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	USP8 protein levels (SeqId = 13450-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	USP8 protein levels (SeqId = 13450-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin carboxyl-terminal hydrolase 8	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000022	None	Gadd-DA_usp8_protein_levels__seqid___13450-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJC17 protein levels (SeqId = 14655-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJC17 protein levels (SeqId = 14655-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily C member 17	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000022	None	Gadd-DA_dnajc17_protein_levels__seqid___14655-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ERH protein levels (SeqId = 11614-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ERH protein levels (SeqId = 11614-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Enhancer of rudimentary homolog	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000022	None	Gadd-DA_erh_protein_levels__seqid___11614-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BID protein levels (SeqId = 5798-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BID protein levels (SeqId = 5798-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BH3-interacting domain death agonist	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000022	None	Gadd-DA_bid_protein_levels__seqid___5798-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0390695	0.00825027	0.000002205186	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0390112	0.00825029	0.000002283292	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MYL12B protein levels (SeqId = 19122-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYL12B protein levels (SeqId = 19122-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Myosin regulatory light chain 12B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000023	None	Gadd-DA_myl12b_protein_levels__seqid___19122-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	B4GALT7 protein levels (SeqId = 7806-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	B4GALT7 protein levels (SeqId = 7806-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-1,4-galactosyltransferase 7	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000023	None	Gadd-DA_b4galt7_protein_levels__seqid___7806-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCL5 protein levels (SeqId = 5480-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCL5 protein levels (SeqId = 5480-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-C motif chemokine 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000023	None	Gadd-DA_ccl5_protein_levels__seqid___5480-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NEK7 protein levels (SeqId = 12703-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NEK7 protein levels (SeqId = 12703-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase Nek7	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000023	None	Gadd-DA_nek7_protein_levels__seqid___12703-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB11A protein levels (SeqId = 17744-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB11A protein levels (SeqId = 17744-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-11A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000023	None	Gadd-DA_rab11a_protein_levels__seqid___17744-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF6 protein levels (SeqId = 4130-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF6 protein levels (SeqId = 4130-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000023	None	Gadd-DA_fgf6_protein_levels__seqid___4130-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ERP29 protein levels (SeqId = 13728-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ERP29 protein levels (SeqId = 13728-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endoplasmic reticulum resident protein 29	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000023	None	Gadd-DA_erp29_protein_levels__seqid___13728-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.0389918	0.00825029	0.000002309922	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0389548	0.0082503	0.000002361326	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0456836	0.00967774	0.000002374679	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0389307	0.00825031	0.000002395499	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0457282	0.00969118	0.000002397382	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0389283	0.00825031	0.000002398989	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.00632	0.00134	0.0000024	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	FAF2 protein levels (SeqId = 9738-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAF2 protein levels (SeqId = 9738-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: FAS-associated factor 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000024	None	Gadd-DA_faf2_protein_levels__seqid___9738-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PGLS protein levels (SeqId = 17799-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGLS protein levels (SeqId = 17799-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 6-phosphogluconolactonase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000024	None	Gadd-DA_pgls_protein_levels__seqid___17799-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VPS4A protein levels (SeqId = 11476-43)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VPS4A protein levels (SeqId = 11476-43)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vacuolar protein sorting-associated protein 4A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000024	None	Gadd-DA_vps4a_protein_levels__seqid___11476-43__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.05	0.0107	0.0000024	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01469549	chr7:157129690	7	157129690	DNAJB6	Island	0.0023	0.00048	0.0000025	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	LST1 protein levels (SeqId = 9531-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LST1 protein levels (SeqId = 9531-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leukocyte-specific transcript 1 protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000025	None	Gadd-DA_lst1_protein_levels__seqid___9531-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	OLA1 protein levels (SeqId = 12659-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	OLA1 protein levels (SeqId = 12659-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Obg-like ATPase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000025	None	Gadd-DA_ola1_protein_levels__seqid___12659-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADH6 protein levels (SeqId = 18206-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADH6 protein levels (SeqId = 18206-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alcohol dehydrogenase 6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000025	None	Gadd-DA_adh6_protein_levels__seqid___18206-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SEZ6L2 protein levels (SeqId = 3867-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SEZ6L2 protein levels (SeqId = 3867-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Seizure 6-like protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000025	None	Gadd-DA_sez6l2_protein_levels__seqid___3867-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRB10 protein levels (SeqId = 11358-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRB10 protein levels (SeqId = 11358-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Growth factor receptor-bound protein 10	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000025	None	Gadd-DA_grb10_protein_levels__seqid___11358-15__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0388214	0.00825035	0.000002556529	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	0.0381853	0.00811687	0.000002568962	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	0.0463021	0.00984259	0.000002571195	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	FST protein levels (SeqId = 4132-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FST protein levels (SeqId = 4132-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Follistatin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000026	None	Gadd-DA_fst_protein_levels__seqid___4132-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HDGF protein levels (SeqId = 8953-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDGF protein levels (SeqId = 8953-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatoma-derived growth factor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000026	None	Gadd-DA_hdgf_protein_levels__seqid___8953-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	JAM3 protein levels (SeqId = 2998-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	JAM3 protein levels (SeqId = 2998-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Junctional adhesion molecule C	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000026	None	Gadd-DA_jam3_protein_levels__seqid___2998-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LAP3 protein levels (SeqId = 13959-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LAP3 protein levels (SeqId = 13959-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytosol aminopeptidase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000026	None	Gadd-DA_lap3_protein_levels__seqid___13959-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TPI1 protein levels (SeqId = 4309-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TPI1 protein levels (SeqId = 4309-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Triosephosphate isomerase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000026	None	Gadd-DA_tpi1_protein_levels__seqid___4309-59__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	0.0387562	0.00825037	0.000002657354	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0419254	0.00892591	0.000002663399	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	ALDOA protein levels (SeqId = 5864-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALDOA protein levels (SeqId = 5864-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fructose-bisphosphate aldolase A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000027	None	Gadd-DA_aldoa_protein_levels__seqid___5864-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GDI2 protein levels (SeqId = 2647-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GDI2 protein levels (SeqId = 2647-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rab GDP dissociation inhibitor beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000027	None	Gadd-DA_gdi2_protein_levels__seqid___2647-66__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS5 protein levels (SeqId = 19195-85)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS5 protein levels (SeqId = 19195-85)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 40S ribosomal protein S5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000027	None	Gadd-DA_rps5_protein_levels__seqid___19195-85__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.599784	0.1279	0.00000273	None	27105112_hiv_infection_cd4_tcells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03996020	chr7:157180124	7	157180124	DNAJB6	Open sea	0.038689	0.00825039	0.000002765439	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.038675	0.00825039	0.000002788442	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CBR3 protein levels (SeqId = 14091-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBR3 protein levels (SeqId = 14091-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carbonyl reductase [NADPH] 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000028	None	Gadd-DA_cbr3_protein_levels__seqid___14091-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MTHFD1 protein levels (SeqId = 12575-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MTHFD1 protein levels (SeqId = 12575-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-1-tetrahydrofolate synthase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000028	None	Gadd-DA_mthfd1_protein_levels__seqid___12575-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF5A protein levels (SeqId = 5888-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF5A protein levels (SeqId = 5888-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 5A-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000028	None	Gadd-DA_eif5a_protein_levels__seqid___5888-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDPK1 protein levels (SeqId = 4460-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDPK1 protein levels (SeqId = 4460-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 3-phosphoinositide-dependent protein kinase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000028	None	Gadd-DA_pdpk1_protein_levels__seqid___4460-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NCR2 protein levels (SeqId = 2734-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NCR2 protein levels (SeqId = 2734-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Natural cytotoxicity triggering receptor 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000028	None	Gadd-DA_ncr2_protein_levels__seqid___2734-49__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.0005	None	0.0000028	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0637327	0.0135985	0.000002800842	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0386532	0.0082504	0.0000028246	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.0386472	0.0082504	0.000002834667	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	0.0386232	0.00825041	0.000002875116	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0520863	0.0111291	0.00000289144	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0386112	0.00825041	0.000002895638	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	0.0025	None	0.0000029	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	NT5C protein levels (SeqId = 12560-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NT5C protein levels (SeqId = 12560-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 5'(3')-deoxyribonucleotidase, cytosolic type	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000029	None	Gadd-DA_nt5c_protein_levels__seqid___12560-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APEX1 protein levels (SeqId = 9849-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APEX1 protein levels (SeqId = 9849-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA-(apurinic or apyrimidinic site) lyase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000029	None	Gadd-DA_apex1_protein_levels__seqid___9849-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKCQ protein levels (SeqId = 3817-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKCQ protein levels (SeqId = 3817-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein kinase C theta type	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000029	None	Gadd-DA_prkcq_protein_levels__seqid___3817-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDRG1 protein levels (SeqId = 12593-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDRG1 protein levels (SeqId = 12593-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: p53 and DNA damage-regulated protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000029	None	Gadd-DA_pdrg1_protein_levels__seqid___12593-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TKT protein levels (SeqId = 4306-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TKT protein levels (SeqId = 4306-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transketolase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000029	None	Gadd-DA_tkt_protein_levels__seqid___4306-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP3R1 protein levels (SeqId = 15545-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP3R1 protein levels (SeqId = 15545-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcineurin subunit B type 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000029	None	Gadd-DA_ppp3r1_protein_levels__seqid___15545-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STUB1 protein levels (SeqId = 11350-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STUB1 protein levels (SeqId = 11350-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase CHIP	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.6	0.127	0.0000029	None	Gadd-DA_stub1_protein_levels__seqid___11350-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKACA protein levels (SeqId = 3466-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKACA protein levels (SeqId = 3466-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: cAMP-dependent protein kinase catalytic subunit alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000029	None	Gadd-DA_prkaca_protein_levels__seqid___3466-8__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0386005	0.00825042	0.000002914055	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0398562	0.00852198	0.000002938803	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02271119	chr7:157198869	7	157198869	DNAJB6	North shelf	-0.0385769	0.00825043	0.000002954973	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0385761	0.00825043	0.000002956275	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	0.0385573	0.00825043	0.000002989293	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE3A protein levels (SeqId = 11226-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE3A protein levels (SeqId = 11226-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-protein ligase E3A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.000003	None	Gadd-DA_ube3a_protein_levels__seqid___11226-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPKAPK3 protein levels (SeqId = 3822-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPKAPK3 protein levels (SeqId = 3822-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAP kinase-activated protein kinase 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.000003	None	Gadd-DA_mapkapk3_protein_levels__seqid___3822-54__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	POLR2K protein levels (SeqId = 19134-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	POLR2K protein levels (SeqId = 19134-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA-directed RNA polymerases I, II, and III subunit RPABC4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.000003	None	Gadd-DA_polr2k_protein_levels__seqid___19134-66__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CILP protein levels (SeqId = 5717-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CILP protein levels (SeqId = 5717-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cartilage intermediate layer protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.000003	None	Gadd-DA_cilp_protein_levels__seqid___5717-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	0.0384979	0.00825045	0.000003095929	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05090392	chr7:157209531	7	157209531	DNAJB6	South shore	0.0074	None	0.0000031	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.00042	0.000089	0.0000031	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Gadd DA	Generation Scotland	35945220	31/07/2022	TYK2 protein levels (SeqId = 5260-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TYK2 protein levels (SeqId = 5260-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Non-receptor tyrosine-protein kinase TYK2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000031	None	Gadd-DA_tyk2_protein_levels__seqid___5260-80__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNRC6B protein levels (SeqId = 9808-41)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNRC6B protein levels (SeqId = 9808-41)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Trinucleotide repeat-containing gene 6B protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000031	None	Gadd-DA_tnrc6b_protein_levels__seqid___9808-41__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANGPT1 protein levels (SeqId = 2811-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANGPT1 protein levels (SeqId = 2811-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Angiopoietin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000031	None	Gadd-DA_angpt1_protein_levels__seqid___2811-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB5C protein levels (SeqId = 14287-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB5C protein levels (SeqId = 14287-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-5C	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000031	None	Gadd-DA_rab5c_protein_levels__seqid___14287-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NUDT3 protein levels (SeqId = 12796-44)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUDT3 protein levels (SeqId = 12796-44)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Diphosphoinositol polyphosphate phosphohydrolase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000031	None	Gadd-DA_nudt3_protein_levels__seqid___12796-44__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSP90AB1 protein levels (SeqId = 5467-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSP90AB1 protein levels (SeqId = 5467-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heat shock protein HSP 90-beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000031	None	Gadd-DA_hsp90ab1_protein_levels__seqid___5467-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDX19B protein levels (SeqId = 5460-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDX19B protein levels (SeqId = 5460-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ATP-dependent RNA helicase DDX19B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000031	None	Gadd-DA_ddx19b_protein_levels__seqid___5460-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AHSA1 protein levels (SeqId = 11633-89)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AHSA1 protein levels (SeqId = 11633-89)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Activator of 90 kDa heat shock protein ATPase homolog 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000031	None	Gadd-DA_ahsa1_protein_levels__seqid___11633-89__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0384939	0.00825045	0.000003103283	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0494529	0.0106077	0.000003159754	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.0384503	0.00825047	0.000003184063	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MAX protein levels (SeqId = 12411-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAX protein levels (SeqId = 12411-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein max	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000032	None	Gadd-DA_max_protein_levels__seqid___12411-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPSS1 protein levels (SeqId = 14007-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPSS1 protein levels (SeqId = 14007-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000032	None	Gadd-DA_papss1_protein_levels__seqid___14007-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VEGFC protein levels (SeqId = 3132-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VEGFC protein levels (SeqId = 3132-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vascular endothelial growth factor C	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.593	0.127	0.0000032	None	Gadd-DA_vegfc_protein_levels__seqid___3132-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNX8 protein levels (SeqId = 6925-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNX8 protein levels (SeqId = 6925-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sorting nexin-8	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000032	None	Gadd-DA_snx8_protein_levels__seqid___6925-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCL27 protein levels (SeqId = 2192-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCL27 protein levels (SeqId = 2192-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-C motif chemokine 27	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000032	None	Gadd-DA_ccl27_protein_levels__seqid___2192-63__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHMT1 protein levels (SeqId = 12334-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHMT1 protein levels (SeqId = 12334-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine hydroxymethyltransferase, cytosolic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.126	0.0000032	None	Gadd-DA_shmt1_protein_levels__seqid___12334-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CD47 protein levels (SeqId = 6653-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD47 protein levels (SeqId = 6653-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leukocyte surface antigen CD47	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000032	None	Gadd-DA_cd47_protein_levels__seqid___6653-58__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.038415	0.00825048	0.000003250902	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	POGLUT1 protein levels (SeqId = 6467-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	POGLUT1 protein levels (SeqId = 6467-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein O-glucosyltransferase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000033	None	Gadd-DA_poglut1_protein_levels__seqid___6467-65__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02271119	chr7:157198869	7	157198869	DNAJB6	North shelf	-0.0383819	0.00825049	0.000003314743	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	AP2A2 protein levels (SeqId = 13621-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AP2A2 protein levels (SeqId = 13621-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AP-2 complex subunit alpha-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000034	None	Gadd-DA_ap2a2_protein_levels__seqid___13621-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJC10 protein levels (SeqId = 8297-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJC10 protein levels (SeqId = 8297-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily C member 10	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000034	None	Gadd-DA_dnajc10_protein_levels__seqid___8297-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NUDT16L1 protein levels (SeqId = 12497-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUDT16L1 protein levels (SeqId = 12497-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tudor-interacting repair regulator protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000034	None	Gadd-DA_nudt16l1_protein_levels__seqid___12497-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB1B protein levels (SeqId = 19278-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB1B protein levels (SeqId = 19278-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-1B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000034	None	Gadd-DA_rab1b_protein_levels__seqid___19278-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACP1 protein levels (SeqId = 3858-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACP1 protein levels (SeqId = 3858-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Low molecular weight phosphotyrosine protein phosphatase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000034	None	Gadd-DA_acp1_protein_levels__seqid___3858-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0451175	0.00971005	0.000003406013	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0450282	0.00969255	0.000003419491	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0383125	0.00825051	0.000003452802	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	DOK2 protein levels (SeqId = 14246-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DOK2 protein levels (SeqId = 14246-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Docking protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000035	None	Gadd-DA_dok2_protein_levels__seqid___14246-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	WSCD2 protein levels (SeqId = 6274-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WSCD2 protein levels (SeqId = 6274-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: WSC domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000035	None	Gadd-DA_wscd2_protein_levels__seqid___6274-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HIBCH protein levels (SeqId = 12396-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HIBCH protein levels (SeqId = 12396-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000035	None	Gadd-DA_hibch_protein_levels__seqid___12396-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0427803	0.00921894	0.000003506182	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09710771	chr7:157199809	7	157199809	DNAJB6	North shelf	-0.00079	0.00017	0.0000036	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	UBXN4 protein levels (SeqId = 9997-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBXN4 protein levels (SeqId = 9997-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UBX domain-containing protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000036	None	Gadd-DA_ubxn4_protein_levels__seqid___9997-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2G1 protein levels (SeqId = 17158-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2G1 protein levels (SeqId = 17158-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 G1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000036	None	Gadd-DA_ube2g1_protein_levels__seqid___17158-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AKR7A2 protein levels (SeqId = 4188-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKR7A2 protein levels (SeqId = 4188-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aflatoxin B1 aldehyde reductase member 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000036	None	Gadd-DA_akr7a2_protein_levels__seqid___4188-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.0382308	0.00825054	0.000003622078	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0382291	0.00825054	0.000003625754	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Lung Cancer	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Lung Cancer	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18364	1	Adults (18-65y)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.01	0.00219	0.0000037	None	Robert-F-Hillary_Incident_Lung_Cancer_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	MAP2K2 protein levels (SeqId = 3628-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAP2K2 protein levels (SeqId = 3628-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dual specificity mitogen-activated protein kinase kinase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000037	None	Gadd-DA_map2k2_protein_levels__seqid___3628-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDK1 protein levels (SeqId = 5227-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDK1 protein levels (SeqId = 5227-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000037	None	Gadd-DA_pdk1_protein_levels__seqid___5227-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SERPINE2 protein levels (SeqId = 19154-41)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SERPINE2 protein levels (SeqId = 19154-41)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glia-derived nexin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000037	None	Gadd-DA_serpine2_protein_levels__seqid___19154-41__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPBP protein levels (SeqId = 4544-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPBP protein levels (SeqId = 4544-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet basic protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000037	None	Gadd-DA_ppbp_protein_levels__seqid___4544-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DYNLL2 protein levels (SeqId = 11493-169)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DYNLL2 protein levels (SeqId = 11493-169)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dynein light chain 2, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000037	None	Gadd-DA_dynll2_protein_levels__seqid___11493-169__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27496299	chr7:157171202	7	157171202	DNAJB6	Open sea	-0.0059	0.0013	0.0000037	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.025	0.00538	0.0000037	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.038193	0.00825055	0.000003703168	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	0.0381672	0.00825056	0.000003759566	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	WWP1 protein levels (SeqId = 11307-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WWP1 protein levels (SeqId = 11307-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NEDD4-like E3 ubiquitin-protein ligase WWP1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000038	None	Gadd-DA_wwp1_protein_levels__seqid___11307-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL20 protein levels (SeqId = 4138-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL20 protein levels (SeqId = 4138-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-20	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.126	0.0000038	None	Gadd-DA_il20_protein_levels__seqid___4138-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS19 protein levels (SeqId = 19166-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS19 protein levels (SeqId = 19166-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 40S ribosomal protein S19	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000038	None	Gadd-DA_rps19_protein_levels__seqid___19166-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SELP protein levels (SeqId = 4154-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SELP protein levels (SeqId = 4154-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: P-selectin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000038	None	Gadd-DA_selp_protein_levels__seqid___4154-57__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0381415	0.00825056	0.000003816361	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PPME1 protein levels (SeqId = 17852-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPME1 protein levels (SeqId = 17852-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein phosphatase methylesterase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000039	None	Gadd-DA_ppme1_protein_levels__seqid___17852-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HINT2 protein levels (SeqId = 5612-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HINT2 protein levels (SeqId = 5612-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histidine triad nucleotide-binding protein 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000039	None	Gadd-DA_hint2_protein_levels__seqid___5612-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0451631	0.00978716	0.000003973275	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0067	0.0015	0.000004	-	27651444_smoking_current_vs_never_smoking
Gadd DA	Generation Scotland	35945220	31/07/2022	BLVRA protein levels (SeqId = 11382-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BLVRA protein levels (SeqId = 11382-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Biliverdin reductase A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.000004	None	Gadd-DA_blvra_protein_levels__seqid___11382-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APBB2 protein levels (SeqId = 12753-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APBB2 protein levels (SeqId = 12753-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Amyloid-beta A4 precursor protein-binding family B member 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.588	0.127	0.000004	None	Gadd-DA_apbb2_protein_levels__seqid___12753-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RRM2B protein levels (SeqId = 8925-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RRM2B protein levels (SeqId = 8925-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribonucleoside-diphosphate reductase subunit M2 B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.000004	None	Gadd-DA_rrm2b_protein_levels__seqid___8925-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDK8 protein levels (SeqId = 3359-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDK8 protein levels (SeqId = 3359-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cyclin-dependent kinase 8|Cyclin-C	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.000004	None	Gadd-DA_cdk8_protein_levels__seqid___3359-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NT5C2 protein levels (SeqId = 11288-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NT5C2 protein levels (SeqId = 11288-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytosolic purine 5'-nucleotidase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.000004	None	Gadd-DA_nt5c2_protein_levels__seqid___11288-26__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0419347	0.00909743	0.000004070118	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	0.0380194	0.0082506	0.00000409829	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.00301	0.00065	0.0000041	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Inkster A	Seven dataset from four North American cohorts. GSE73375, GSE75428, GSE98224, GSE74738, GSE100197, GSE108567, and GSE128827	34044884	03-08-2021	Sex	PATO_0001894	Discovery	Supplementary Table 1	DNA methylation	Sex	Ancestry (genomic PCs), Gestational age, Dataset	M values	None	Illumina HumanMethylation450	Placenta	None	585	4	Infants	Both	European, East Asian, African, Admixed	cg11695266	chr7:157129166	7	157129166	DNAJB6	Island	3.9	None	0.0000041	None	34044884_Inkster-A_sex_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	NPL protein levels (SeqId = 19496-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NPL protein levels (SeqId = 19496-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-acetylneuraminate lyase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000041	None	Gadd-DA_npl_protein_levels__seqid___19496-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AKR1A1 protein levels (SeqId = 4192-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKR1A1 protein levels (SeqId = 4192-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aldo-keto reductase family 1 member A1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000041	None	Gadd-DA_akr1a1_protein_levels__seqid___4192-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ICOSLG protein levels (SeqId = 5061-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ICOSLG protein levels (SeqId = 5061-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ICOS ligand	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000041	None	Gadd-DA_icoslg_protein_levels__seqid___5061-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDKN1A protein levels (SeqId = 18291-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDKN1A protein levels (SeqId = 18291-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cyclin-dependent kinase inhibitor 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000041	None	Gadd-DA_cdkn1a_protein_levels__seqid___18291-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PTGES2 protein levels (SeqId = 18458-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTGES2 protein levels (SeqId = 18458-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prostaglandin E synthase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000041	None	Gadd-DA_ptges2_protein_levels__seqid___18458-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0380146	0.0082506	0.000004109725	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.038005	0.00825061	0.000004132893	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	G6PD protein levels (SeqId = 19297-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	G6PD protein levels (SeqId = 19297-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glucose-6-phosphate 1-dehydrogenase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000042	None	Gadd-DA_g6pd_protein_levels__seqid___19297-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GCDH protein levels (SeqId = 19258-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GCDH protein levels (SeqId = 19258-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutaryl-CoA dehydrogenase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.59	0.127	0.0000042	None	Gadd-DA_gcdh_protein_levels__seqid___19258-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDCD6IP protein levels (SeqId = 18174-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDCD6IP protein levels (SeqId = 18174-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Programmed cell death 6-interacting protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000042	None	Gadd-DA_pdcd6ip_protein_levels__seqid___18174-79__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DLX4 protein levels (SeqId = 11910-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DLX4 protein levels (SeqId = 11910-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Homeobox protein DLX-4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000042	None	Gadd-DA_dlx4_protein_levels__seqid___11910-27__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	0.0379402	0.00825063	0.000004291861	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMA protein levels (SeqId = 3440-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMA protein levels (SeqId = 3440-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme A	774	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.85	0.184	0.0000043	None	Gadd-DA_gzma_protein_levels__seqid___3440-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DLG3 protein levels (SeqId = 7897-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DLG3 protein levels (SeqId = 7897-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Disks large homolog 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.126	0.0000043	None	Gadd-DA_dlg3_protein_levels__seqid___7897-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMG3 protein levels (SeqId = 12729-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMG3 protein levels (SeqId = 12729-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteasome assembly chaperone 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000043	None	Gadd-DA_psmg3_protein_levels__seqid___12729-12__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0379354	0.00825063	0.000004303711	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0445525	0.00969271	0.000004332493	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0488731	0.0106387	0.000004386783	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB11 protein levels (SeqId = 7110-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB11 protein levels (SeqId = 7110-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 11	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000044	None	Gadd-DA_dnajb11_protein_levels__seqid___7110-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KIAA0040 protein levels (SeqId = 14603-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIAA0040 protein levels (SeqId = 14603-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uncharacterized protein KIAA0040	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000044	None	Gadd-DA_kiaa0040_protein_levels__seqid___14603-51__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11695266	chr7:157129166	7	157129166	DNAJB6	Island	0.0391509	0.00852403	0.000004405474	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRC59 protein levels (SeqId = 19163-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRC59 protein levels (SeqId = 19163-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leucine-rich repeat-containing protein 59	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000045	None	Gadd-DA_lrrc59_protein_levels__seqid___19163-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C11orf87 protein levels (SeqId = 11116-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C11orf87 protein levels (SeqId = 11116-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uncharacterized protein C11orf87	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000045	None	Gadd-DA_c11orf87_protein_levels__seqid___11116-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0409422	0.00892556	0.000004532273	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	NFU1 protein levels (SeqId = 7770-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NFU1 protein levels (SeqId = 7770-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NFU1 iron-sulfur cluster scaffold homolog, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.583	0.127	0.0000046	None	Gadd-DA_nfu1_protein_levels__seqid___7770-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPT1 protein levels (SeqId = 9244-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPT1 protein levels (SeqId = 9244-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Palmitoyl-protein thioesterase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000046	None	Gadd-DA_ppt1_protein_levels__seqid___9244-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNRPG protein levels (SeqId = 19276-124)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNRPG protein levels (SeqId = 19276-124)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Small nuclear ribonucleoprotein G	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000046	None	Gadd-DA_snrpg_protein_levels__seqid___19276-124__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SYK protein levels (SeqId = 11378-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SYK protein levels (SeqId = 11378-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase SYK	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000046	None	Gadd-DA_syk_protein_levels__seqid___11378-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COMMD9 protein levels (SeqId = 17683-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COMMD9 protein levels (SeqId = 17683-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: COMM domain-containing protein 9	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000046	None	Gadd-DA_commd9_protein_levels__seqid___17683-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MOBKL1A protein levels (SeqId = 19177-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MOBKL1A protein levels (SeqId = 19177-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MOB kinase activator 1B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000046	None	Gadd-DA_mobkl1a_protein_levels__seqid___19177-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AIF1 protein levels (SeqId = 2849-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AIF1 protein levels (SeqId = 2849-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Allograft inflammatory factor 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000046	None	Gadd-DA_aif1_protein_levels__seqid___2849-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CACNB4 protein levels (SeqId = 11130-158)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CACNB4 protein levels (SeqId = 11130-158)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Voltage-dependent L-type calcium channel subunit beta-4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000047	None	Gadd-DA_cacnb4_protein_levels__seqid___11130-158__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	WISP1 protein levels (SeqId = 13692-154)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WISP1 protein levels (SeqId = 13692-154)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: WNT1-inducible-signaling pathway protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.582	0.127	0.0000047	None	Gadd-DA_wisp1_protein_levels__seqid___13692-154__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPIA protein levels (SeqId = 3844-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPIA protein levels (SeqId = 3844-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000047	None	Gadd-DA_ppia_protein_levels__seqid___3844-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NIP7 protein levels (SeqId = 12564-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NIP7 protein levels (SeqId = 12564-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 60S ribosome subunit biogenesis protein NIP7 homolog	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000047	None	Gadd-DA_nip7_protein_levels__seqid___12564-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.0377823	0.00825068	0.000004703651	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Hannon E	-	27572077	2016-08-30	Schizophrenia	EFO_0000692	Phase 1	Table S3	DNA methylation	Schizophrenia	Age, sex, smoking, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	675	1	-	Missing	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.012829	0.002804	0.00000476	-	27572077_schizophrenia_phase_1
Gadd DA	Generation Scotland	35945220	31/07/2022	C5orf46 protein levels (SeqId = 9100-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C5orf46 protein levels (SeqId = 9100-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uncharacterized protein C5orf46	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000048	None	Gadd-DA_c5orf46_protein_levels__seqid___9100-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRL protein levels (SeqId = 2585-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRL protein levels (SeqId = 2585-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prolactin	774	1	Adults (18-65 years)	Both	European	cg15248935	chr7:157180055	7	157180055	DNAJB6	Open sea	-0.91	0.2	0.0000049	None	Gadd-DA_prl_protein_levels__seqid___2585-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KLC1 protein levels (SeqId = 12656-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLC1 protein levels (SeqId = 12656-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kinesin light chain 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000049	None	Gadd-DA_klc1_protein_levels__seqid___12656-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TSTD1 protein levels (SeqId = 19277-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TSTD1 protein levels (SeqId = 19277-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thiosulfate:glutathione sulfurtransferase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000049	None	Gadd-DA_tstd1_protein_levels__seqid___19277-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	0.0377108	0.0082507	0.000004902599	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.0451429	0.00987717	0.000004906991	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0062	0.0013	0.000005	-	27651444_smoking_current_vs_never_smoking
Gadd DA	Generation Scotland	35945220	31/07/2022	APLP2 protein levels (SeqId = 10627-87)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APLP2 protein levels (SeqId = 10627-87)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Amyloid-like protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.000005	None	Gadd-DA_aplp2_protein_levels__seqid___10627-87__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAT1 protein levels (SeqId = 10370-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAT1 protein levels (SeqId = 10370-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal transducer and activator of transcription 1-alpha/beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.000005	None	Gadd-DA_stat1_protein_levels__seqid___10370-21__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg12690313	chr7:157129430	7	157129430	DNAJB6	Island	0.131658	0.0288355	0.000005007243	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0376512	0.00825072	0.000005074283	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	0.0028	0.00061	0.0000051	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	PAFAH2 protein levels (SeqId = 18914-188)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAFAH2 protein levels (SeqId = 18914-188)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet-activating factor acetylhydrolase 2, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000051	None	Gadd-DA_pafah2_protein_levels__seqid___18914-188__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHMT2 protein levels (SeqId = 12691-44)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHMT2 protein levels (SeqId = 12691-44)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine hydroxymethyltransferase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000051	None	Gadd-DA_shmt2_protein_levels__seqid___12691-44__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS4X protein levels (SeqId = 9758-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS4X protein levels (SeqId = 9758-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 40S ribosomal protein S4, X isoform	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000051	None	Gadd-DA_rps4x_protein_levels__seqid___9758-17__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0504609	0.0110661	0.000005158309	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	SPINT2 protein levels (SeqId = 2843-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPINT2 protein levels (SeqId = 2843-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kunitz-type protease inhibitor 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000052	None	Gadd-DA_spint2_protein_levels__seqid___2843-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDC37 protein levels (SeqId = 3879-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDC37 protein levels (SeqId = 3879-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hsp90 co-chaperone Cdc37	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000052	None	Gadd-DA_cdc37_protein_levels__seqid___3879-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RBM17 protein levels (SeqId = 17391-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RBM17 protein levels (SeqId = 17391-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Splicing factor 45	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000052	None	Gadd-DA_rbm17_protein_levels__seqid___17391-10__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0375879	0.00825074	0.000005263154	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ARID3A protein levels (SeqId = 3875-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARID3A protein levels (SeqId = 3875-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AT-rich interactive domain-containing protein 3A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000053	None	Gadd-DA_arid3a_protein_levels__seqid___3875-62__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZYX protein levels (SeqId = 13632-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZYX protein levels (SeqId = 13632-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Zyxin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000053	None	Gadd-DA_zyx_protein_levels__seqid___13632-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RDX protein levels (SeqId = 18373-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RDX protein levels (SeqId = 18373-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Radixin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000053	None	Gadd-DA_rdx_protein_levels__seqid___18373-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPG21 protein levels (SeqId = 11122-97)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPG21 protein levels (SeqId = 11122-97)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Maspardin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000053	None	Gadd-DA_spg21_protein_levels__seqid___11122-97__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	0.0375667	0.00825074	0.000005327744	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	ch.7.3356624R	chr7:157205374	7	157205374	DNAJB6	North shore	-0.366227	0.0805	0.00000534	-	27105112_hiv_infection_neutrophils
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.0375586	0.00825075	0.000005352912	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ID2 protein levels (SeqId = 15403-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ID2 protein levels (SeqId = 15403-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA-binding protein inhibitor ID-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.578	0.127	0.0000054	None	Gadd-DA_id2_protein_levels__seqid___15403-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IGBP1 protein levels (SeqId = 12358-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IGBP1 protein levels (SeqId = 12358-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000054	None	Gadd-DA_igbp1_protein_levels__seqid___12358-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ASMTL protein levels (SeqId = 10089-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASMTL protein levels (SeqId = 10089-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000054	None	Gadd-DA_asmtl_protein_levels__seqid___10089-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.050559	0.0111112	0.000005400369	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	0.0375323	0.00825075	0.00000543459	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0885251	0.0194618	0.000005442113	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.060768	0.0133635	0.000005477194	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	-0.0375161	0.00825076	0.000005485424	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GPCPD1 protein levels (SeqId = 12786-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GPCPD1 protein levels (SeqId = 12786-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycerophosphocholine phosphodiesterase GPCPD1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000056	None	Gadd-DA_gpcpd1_protein_levels__seqid___12786-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TOX3 protein levels (SeqId = 12717-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TOX3 protein levels (SeqId = 12717-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: TOX high mobility group box family member 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.126	0.0000056	None	Gadd-DA_tox3_protein_levels__seqid___12717-65__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COL23A1 protein levels (SeqId = 4543-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COL23A1 protein levels (SeqId = 4543-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen alpha-1(XXIII) chain	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000057	None	Gadd-DA_col23a1_protein_levels__seqid___4543-65__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EDAR protein levels (SeqId = 2977-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EDAR protein levels (SeqId = 2977-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor receptor superfamily member EDAR	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000057	None	Gadd-DA_edar_protein_levels__seqid___2977-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ULBP3 protein levels (SeqId = 2747-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ULBP3 protein levels (SeqId = 2747-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UL16-binding protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000057	None	Gadd-DA_ulbp3_protein_levels__seqid___2747-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSMD1 protein levels (SeqId = 9598-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSMD1 protein levels (SeqId = 9598-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: CUB and sushi domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000057	None	Gadd-DA_csmd1_protein_levels__seqid___9598-23__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0500798	0.0110385	0.000005755534	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	RPL12 protein levels (SeqId = 19183-164)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPL12 protein levels (SeqId = 19183-164)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 60S ribosomal protein L12	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000058	None	Gadd-DA_rpl12_protein_levels__seqid___19183-164__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NAA10 protein levels (SeqId = 17854-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAA10 protein levels (SeqId = 17854-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-alpha-acetyltransferase 10	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.576	0.127	0.0000058	None	Gadd-DA_naa10_protein_levels__seqid___17854-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COCH protein levels (SeqId = 7227-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COCH protein levels (SeqId = 7227-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cochlin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.126	0.0000059	None	Gadd-DA_coch_protein_levels__seqid___7227-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AK2 protein levels (SeqId = 11368-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AK2 protein levels (SeqId = 11368-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adenylate kinase 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000059	None	Gadd-DA_ak2_protein_levels__seqid___11368-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ALDH1A3 protein levels (SeqId = 9835-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALDH1A3 protein levels (SeqId = 9835-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aldehyde dehydrogenase family 1 member A3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000059	None	Gadd-DA_aldh1a3_protein_levels__seqid___9835-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0373647	0.00825081	0.000005984145	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	HSPB1 protein levels (SeqId = 11103-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSPB1 protein levels (SeqId = 11103-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heat shock protein beta-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.576	0.127	0.000006	None	Gadd-DA_hspb1_protein_levels__seqid___11103-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BCL2 protein levels (SeqId = 3412-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BCL2 protein levels (SeqId = 3412-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Apoptosis regulator Bcl-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.000006	None	Gadd-DA_bcl2_protein_levels__seqid___3412-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PARVA protein levels (SeqId = 13434-172)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PARVA protein levels (SeqId = 13434-172)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-parvin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.126	0.000006	None	Gadd-DA_parva_protein_levels__seqid___13434-172__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0543813	0.0120117	0.000006019645	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0373326	0.00825082	0.000006095262	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Ribs bone mineral density	EFO_0007591	None	None	DNA methylation	Ribs bone mineral density	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g/cm2	Illumina HumanMethylation450	Whole blood	DXA scan measurement	702	1	Adults	Females	European	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	-1.35	0.3	0.0000061	None	Battram-T_ribs_bone_mineral_density
Gadd DA	Generation Scotland	35945220	31/07/2022	SYF2 protein levels (SeqId = 19438-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SYF2 protein levels (SeqId = 19438-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pre-mRNA-splicing factor SYF2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000061	None	Gadd-DA_syf2_protein_levels__seqid___19438-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VAV1 protein levels (SeqId = 5275-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VAV1 protein levels (SeqId = 5275-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proto-oncogene vav	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000061	None	Gadd-DA_vav1_protein_levels__seqid___5275-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0552348	0.0122168	0.000006196092	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPD protein levels (SeqId = 18348-89)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPD protein levels (SeqId = 18348-89)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein D0	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000062	None	Gadd-DA_hnrnpd_protein_levels__seqid___18348-89__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.037285	0.00825083	0.000006263549	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	VIP protein levels (SeqId = 3522-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VIP protein levels (SeqId = 3522-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: VIP peptides	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.58	0.127	0.0000063	None	Gadd-DA_vip_protein_levels__seqid___3522-57__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPAB protein levels (SeqId = 8894-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPAB protein levels (SeqId = 8894-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein A/B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000063	None	Gadd-DA_hnrnpab_protein_levels__seqid___8894-80__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0372447	0.00825084	0.000006409537	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17483	1	Adults (18-65y)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.021	0.00461	0.0000065	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	PRPS2 protein levels (SeqId = 18329-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRPS2 protein levels (SeqId = 18329-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribose-phosphate pyrophosphokinase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000065	None	Gadd-DA_prps2_protein_levels__seqid___18329-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KREMEN2 protein levels (SeqId = 3202-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KREMEN2 protein levels (SeqId = 3202-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kremen protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000066	None	Gadd-DA_kremen2_protein_levels__seqid___3202-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BRSK2 protein levels (SeqId = 9790-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BRSK2 protein levels (SeqId = 9790-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase BRSK2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000067	None	Gadd-DA_brsk2_protein_levels__seqid___9790-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RMDN1 protein levels (SeqId = 7096-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RMDN1 protein levels (SeqId = 7096-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Regulator of microtubule dynamics protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000067	None	Gadd-DA_rmdn1_protein_levels__seqid___7096-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MRE11A protein levels (SeqId = 11319-106)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MRE11A protein levels (SeqId = 11319-106)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Double-strand break repair protein MRE11	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000067	None	Gadd-DA_mre11a_protein_levels__seqid___11319-106__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LGALS4 protein levels (SeqId = 2982-82)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LGALS4 protein levels (SeqId = 2982-82)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Galectin-4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000068	None	Gadd-DA_lgals4_protein_levels__seqid___2982-82__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GGA3 protein levels (SeqId = 11683-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GGA3 protein levels (SeqId = 11683-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor-binding protein GGA3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000068	None	Gadd-DA_gga3_protein_levels__seqid___11683-19__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg12577647	chr7:157178981	7	157178981	DNAJB6	Open sea	-0.209838	0.0466469	0.000006887454	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	TIAL1 protein levels (SeqId = 19131-184)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TIAL1 protein levels (SeqId = 19131-184)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nucleolysin TIAR	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000069	None	Gadd-DA_tial1_protein_levels__seqid___19131-184__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSNK2A1 protein levels (SeqId = 5225-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSNK2A1 protein levels (SeqId = 5225-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Casein kinase II subunit beta|Casein kinase II subunit alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000069	None	Gadd-DA_csnk2a1_protein_levels__seqid___5225-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	INPP5E protein levels (SeqId = 11370-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	INPP5E protein levels (SeqId = 11370-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 72 kDa inositol polyphosphate 5-phosphatase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000069	None	Gadd-DA_inpp5e_protein_levels__seqid___11370-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLPP protein levels (SeqId = 17196-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLPP protein levels (SeqId = 17196-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ATP-dependent Clp protease proteolytic subunit, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.573	0.127	0.0000069	None	Gadd-DA_clpp_protein_levels__seqid___17196-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0380023	0.00844858	0.000006910107	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0443789	0.00986712	0.0000069234	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	BCL10 protein levels (SeqId = 8768-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BCL10 protein levels (SeqId = 8768-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: B-cell lymphoma/leukemia 10	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.000007	None	Gadd-DA_bcl10_protein_levels__seqid___8768-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	L3MBTL2 protein levels (SeqId = 12708-91)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	L3MBTL2 protein levels (SeqId = 12708-91)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lethal(3)malignant brain tumor-like protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.000007	None	Gadd-DA_l3mbtl2_protein_levels__seqid___12708-91__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	USO1 protein levels (SeqId = 13639-101)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	USO1 protein levels (SeqId = 13639-101)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: General vesicular transport factor p115	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.000007	None	Gadd-DA_uso1_protein_levels__seqid___13639-101__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NDUFV2 protein levels (SeqId = 7748-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NDUFV2 protein levels (SeqId = 7748-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.000007	None	Gadd-DA_ndufv2_protein_levels__seqid___7748-11__somascan_protein_measurement
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.00037851	8.38e-05	0.00000705	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF1AY protein levels (SeqId = 19224-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF1AY protein levels (SeqId = 19224-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 1A, Y-chromosomal	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000071	None	Gadd-DA_eif1ay_protein_levels__seqid___19224-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BAG1 protein levels (SeqId = 17195-43)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BAG1 protein levels (SeqId = 17195-43)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BAG family molecular chaperone regulator 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000071	None	Gadd-DA_bag1_protein_levels__seqid___17195-43__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL23R protein levels (SeqId = 5088-175)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL23R protein levels (SeqId = 5088-175)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-23 receptor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000072	None	Gadd-DA_il23r_protein_levels__seqid___5088-175__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0493889	0.011005	0.000007249496	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05726556	chr7:157203124	7	157203124	DNAJB6	Island	0.0012	None	0.0000073	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	MAP2K3 protein levels (SeqId = 6151-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAP2K3 protein levels (SeqId = 6151-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dual specificity mitogen-activated protein kinase kinase 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000073	None	Gadd-DA_map2k3_protein_levels__seqid___6151-18__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	0.0490193	0.0109319	0.000007379103	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0369932	0.00825092	0.000007397798	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SEPHS1 protein levels (SeqId = 14083-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SEPHS1 protein levels (SeqId = 14083-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Selenide, water dikinase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000074	None	Gadd-DA_sephs1_protein_levels__seqid___14083-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LCMT1 protein levels (SeqId = 4237-70)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LCMT1 protein levels (SeqId = 4237-70)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leucine carboxyl methyltransferase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000074	None	Gadd-DA_lcmt1_protein_levels__seqid___4237-70__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANP32A protein levels (SeqId = 13073-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANP32A protein levels (SeqId = 13073-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acidic leucine-rich nuclear phosphoprotein 32 family member A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000075	None	Gadd-DA_anp32a_protein_levels__seqid___13073-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDE11A protein levels (SeqId = 5252-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDE11A protein levels (SeqId = 5252-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000075	None	Gadd-DA_pde11a_protein_levels__seqid___5252-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SMAD4 protein levels (SeqId = 12022-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMAD4 protein levels (SeqId = 12022-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mothers against decapentaplegic homolog 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000075	None	Gadd-DA_smad4_protein_levels__seqid___12022-12__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0369612	0.00825093	0.000007533594	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	0.036952	0.00825093	0.000007572651	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	YWHAZ protein levels (SeqId = 5858-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YWHAZ protein levels (SeqId = 5858-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 14-3-3 protein zeta/delta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000076	None	Gadd-DA_ywhaz_protein_levels__seqid___5858-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SIGLEC11 protein levels (SeqId = 8913-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SIGLEC11 protein levels (SeqId = 8913-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sialic acid-binding Ig-like lectin 11	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000076	None	Gadd-DA_siglec11_protein_levels__seqid___8913-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANGPT4 protein levels (SeqId = 2500-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANGPT4 protein levels (SeqId = 2500-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Angiopoietin-4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000076	None	Gadd-DA_angpt4_protein_levels__seqid___2500-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C11orf94 protein levels (SeqId = 8383-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C11orf94 protein levels (SeqId = 8383-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uncharacterized protein C11orf94	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000076	None	Gadd-DA_c11orf94_protein_levels__seqid___8383-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL6 protein levels (SeqId = 4673-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL6 protein levels (SeqId = 4673-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000077	None	Gadd-DA_il6_protein_levels__seqid___4673-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACAT2 protein levels (SeqId = 17341-89)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACAT2 protein levels (SeqId = 17341-89)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acetyl-CoA acetyltransferase, cytosolic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000077	None	Gadd-DA_acat2_protein_levels__seqid___17341-89__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	S100A6 protein levels (SeqId = 13090-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	S100A6 protein levels (SeqId = 13090-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein S100-A6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000077	None	Gadd-DA_s100a6_protein_levels__seqid___13090-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FOXO3 protein levels (SeqId = 11540-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FOXO3 protein levels (SeqId = 11540-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Forkhead box protein O3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000077	None	Gadd-DA_foxo3_protein_levels__seqid___11540-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HTRA2 protein levels (SeqId = 3317-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HTRA2 protein levels (SeqId = 3317-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine protease HTRA2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000078	None	Gadd-DA_htra2_protein_levels__seqid___3317-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHC1 protein levels (SeqId = 5272-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHC1 protein levels (SeqId = 5272-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SHC-transforming protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000078	None	Gadd-DA_shc1_protein_levels__seqid___5272-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RHOG protein levels (SeqId = 12540-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RHOG protein levels (SeqId = 12540-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho-related GTP-binding protein RhoG	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.000008	None	Gadd-DA_rhog_protein_levels__seqid___12540-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SYT17 protein levels (SeqId = 9110-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SYT17 protein levels (SeqId = 9110-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Synaptotagmin-17	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.000008	None	Gadd-DA_syt17_protein_levels__seqid___9110-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARPC3 protein levels (SeqId = 13573-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARPC3 protein levels (SeqId = 13573-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Actin-related protein 2/3 complex subunit 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.000008	None	Gadd-DA_arpc3_protein_levels__seqid___13573-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMD4 protein levels (SeqId = 13568-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMD4 protein levels (SeqId = 13568-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 26S proteasome non-ATPase regulatory subunit 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.000008	None	Gadd-DA_psmd4_protein_levels__seqid___13568-30__somascan_protein_measurement
Fernandez-Jimenez N	Pregnancy And Childhood Epigenetics (PACE)	None	None	maternal pre-pregnancy body mass index	EFO_0004340	inverse variance-weighted fixed effects meta-analysis	https://doi.org/10.5281/zenodo.7314534	DNA methylation	maternal pre-pregnancy body mass index	Maternal age, parity, maternal education, maternal smoking	Beta values	kg/m2	Illumina HumanMethylation450	Placenta	None	2631	10	Infants	Both	European, Unclear	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0012	0.00027	0.0000081	None	Fernandez-Jimenez-N_maternal_pre-pregnancy_body_mass_index_inverse_variance-weighted_fixed_effects_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06504624	chr7:157157215	7	157157215	DNAJB6	Open sea	-0.0087	0.002	0.0000081	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.00058	0.00013	0.0000081	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	NAPA protein levels (SeqId = 4292-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAPA protein levels (SeqId = 4292-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-soluble NSF attachment protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000081	None	Gadd-DA_napa_protein_levels__seqid___4292-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NAP1L4 protein levels (SeqId = 19188-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAP1L4 protein levels (SeqId = 19188-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nucleosome assembly protein 1-like 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000081	None	Gadd-DA_nap1l4_protein_levels__seqid___19188-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DENR protein levels (SeqId = 19287-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DENR protein levels (SeqId = 19287-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Density-regulated protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000082	None	Gadd-DA_denr_protein_levels__seqid___19287-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DUSP15 protein levels (SeqId = 12838-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DUSP15 protein levels (SeqId = 12838-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dual specificity protein phosphatase 15	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.69	0.154	0.0000082	None	Gadd-DA_dusp15_protein_levels__seqid___12838-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NANS protein levels (SeqId = 17802-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NANS protein levels (SeqId = 17802-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sialic acid synthase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000083	None	Gadd-DA_nans_protein_levels__seqid___17802-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGAP25 protein levels (SeqId = 11333-82)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGAP25 protein levels (SeqId = 11333-82)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 25	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000084	None	Gadd-DA_arhgap25_protein_levels__seqid___11333-82__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21240861	chr7:157129652	7	157129652	DNAJB6	Island	-0.000051	0.000012	0.0000085	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0445053	0.00999755	0.000008585371	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	MRRF protein levels (SeqId = 12355-223)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MRRF protein levels (SeqId = 12355-223)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribosome-recycling factor, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000086	None	Gadd-DA_mrrf_protein_levels__seqid___12355-223__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	0.0404101	0.00908412	0.000008713449	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02271119	chr7:157198869	7	157198869	DNAJB6	North shelf	0.0012	None	0.0000088	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	ARL3 protein levels (SeqId = 12571-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARL3 protein levels (SeqId = 12571-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor-like protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000088	None	Gadd-DA_arl3_protein_levels__seqid___12571-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSP90AA1 protein levels (SeqId = 2625-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSP90AA1 protein levels (SeqId = 2625-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heat shock protein HSP 90-alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.0000088	None	Gadd-DA_hsp90aa1_protein_levels__seqid___2625-53__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0494322	0.0111185	0.00000881433	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	0.0366795	0.00825102	0.000008834931	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0491484	0.0110593	0.000008891228	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	IFNL1 protein levels (SeqId = 4396-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFNL1 protein levels (SeqId = 4396-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon lambda-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000089	None	Gadd-DA_ifnl1_protein_levels__seqid___4396-54__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg20723414	chr7:157207071	7	157207071	DNAJB6	Island	-0.903767	0.2035	0.00000896	-	27105112_hiv_infection_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05077108	chr7:157200263	7	157200263	DNAJB6	North shelf	0.0022	None	0.000009	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	CGB2 protein levels (SeqId = 6213-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CGB2 protein levels (SeqId = 6213-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Choriogonadotropin subunit beta variant 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.563	0.127	0.000009	None	Gadd-DA_cgb2_protein_levels__seqid___6213-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FXR1 protein levels (SeqId = 13076-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FXR1 protein levels (SeqId = 13076-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fragile X mental retardation syndrome-related protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.000009	None	Gadd-DA_fxr1_protein_levels__seqid___13076-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDC42BPB protein levels (SeqId = 3629-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDC42BPB protein levels (SeqId = 3629-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase MRCK beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.57	0.127	0.000009	None	Gadd-DA_cdc42bpb_protein_levels__seqid___3629-60__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12690313	chr7:157129430	7	157129430	DNAJB6	Island	0.0017	0.00039	0.0000091	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	SMC3 protein levels (SeqId = 14324-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMC3 protein levels (SeqId = 14324-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Structural maintenance of chromosomes protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000091	None	Gadd-DA_smc3_protein_levels__seqid___14324-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBL4A protein levels (SeqId = 11490-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBL4A protein levels (SeqId = 11490-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-like protein 4A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.126	0.0000091	None	Gadd-DA_ubl4a_protein_levels__seqid___11490-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3BGRL3 protein levels (SeqId = 17490-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3BGRL3 protein levels (SeqId = 17490-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SH3 domain-binding glutamic acid-rich-like protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000092	None	Gadd-DA_sh3bgrl3_protein_levels__seqid___17490-4__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.192233	0.0433304	0.000009201428	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24185680	chr7:157171288	7	157171288	DNAJB6	Open sea	0.0365947	0.00825104	0.000009267038	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	KIR2DL3 protein levels (SeqId = 17153-46)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIR2DL3 protein levels (SeqId = 17153-46)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Killer cell immunoglobulin-like receptor 2DL3	774	1	Adults (18-65 years)	Both	European	cg22044861	chr7:157129591	7	157129591	DNAJB6	Island	0.85	0.191	0.0000093	None	Gadd-DA_kir2dl3_protein_levels__seqid___17153-46__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SULT1A3 protein levels (SeqId = 13944-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SULT1A3 protein levels (SeqId = 13944-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sulfotransferase 1A3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000093	None	Gadd-DA_sult1a3_protein_levels__seqid___13944-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0365846	0.00825104	0.000009320016	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	HIPK3 protein levels (SeqId = 19329-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HIPK3 protein levels (SeqId = 19329-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Homeodomain-interacting protein kinase 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000094	None	Gadd-DA_hipk3_protein_levels__seqid___19329-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ECI2 protein levels (SeqId = 12859-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ECI2 protein levels (SeqId = 12859-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Enoyl-CoA delta isomerase 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000094	None	Gadd-DA_eci2_protein_levels__seqid___12859-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HS3ST4 protein levels (SeqId = 19370-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HS3ST4 protein levels (SeqId = 19370-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heparan sulfate glucosamine 3-O-sulfotransferase 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000095	None	Gadd-DA_hs3st4_protein_levels__seqid___19370-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPOCK1 protein levels (SeqId = 5490-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPOCK1 protein levels (SeqId = 5490-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Testican-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000095	None	Gadd-DA_spock1_protein_levels__seqid___5490-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPBP protein levels (SeqId = 17165-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPBP protein levels (SeqId = 17165-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet basic protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000095	None	Gadd-DA_ppbp_protein_levels__seqid___17165-1__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06416110	chr7:157190100	7	157190100	DNAJB6	North shelf	-0.00046	0.0001	0.0000096	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	PBRM1 protein levels (SeqId = 12518-289)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PBRM1 protein levels (SeqId = 12518-289)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein polybromo-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000096	None	Gadd-DA_pbrm1_protein_levels__seqid___12518-289__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24185680	chr7:157171288	7	157171288	DNAJB6	Open sea	-0.036513	0.00825107	0.000009702632	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0365108	0.00825107	0.000009714798	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0384733	0.0086956	0.000009738438	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	0.0373498	0.00844236	0.000009754584	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0365033	0.00825107	0.000009755483	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PNP protein levels (SeqId = 15435-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PNP protein levels (SeqId = 15435-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Purine nucleoside phosphorylase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.0000099	None	Gadd-DA_pnp_protein_levels__seqid___15435-4__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg12690313	chr7:157129430	7	157129430	DNAJB6	Island	-0.211269	0.0478	0.00000996	-	27105112_hiv_infection_neutrophils
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.00041	0.000092	0.00001	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Gadd DA	Generation Scotland	35945220	31/07/2022	SARS2 protein levels (SeqId = 12348-46)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SARS2 protein levels (SeqId = 12348-46)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine--tRNA ligase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.00001	None	Gadd-DA_sars2_protein_levels__seqid___12348-46__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TBL2 protein levels (SeqId = 11227-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TBL2 protein levels (SeqId = 11227-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transducin beta-like protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.00001	None	Gadd-DA_tbl2_protein_levels__seqid___11227-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MTRF1L protein levels (SeqId = 11134-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MTRF1L protein levels (SeqId = 11134-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptide chain release factor 1-like, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.558	0.126	0.00001	None	Gadd-DA_mtrf1l_protein_levels__seqid___11134-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPDL protein levels (SeqId = 10852-114)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPDL protein levels (SeqId = 10852-114)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein D-like	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.00001	None	Gadd-DA_hnrnpdl_protein_levels__seqid___10852-114__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ITGA2B protein levels (SeqId = 19574-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ITGA2B protein levels (SeqId = 19574-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Integrin alpha-IIb|Integrin beta-3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.00001	None	Gadd-DA_itga2b_protein_levels__seqid___19574-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MTHFSD protein levels (SeqId = 19129-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MTHFSD protein levels (SeqId = 19129-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Methenyltetrahydrofolate synthase domain-containing protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.00001	None	Gadd-DA_mthfsd_protein_levels__seqid___19129-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ATXN3 protein levels (SeqId = 16825-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ATXN3 protein levels (SeqId = 16825-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ataxin-3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.00001	None	Gadd-DA_atxn3_protein_levels__seqid___16825-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	REXO2 protein levels (SeqId = 13590-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	REXO2 protein levels (SeqId = 13590-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Oligoribonuclease, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.00001	None	Gadd-DA_rexo2_protein_levels__seqid___13590-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0395693	0.00896742	0.00001028854	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.03637	0.00825111	0.00001051204	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	-0.0403976	0.00916791	0.00001058399	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0426787	0.00968785	0.00001063457	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.205545	0.0466716	0.0000106878	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03996020	chr7:157180124	7	157180124	DNAJB6	Open sea	-0.036333	0.00825112	0.00001073198	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	-0.036329	0.00825112	0.00001075603	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0427128	0.00970962	0.00001095074	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGAP1 protein levels (SeqId = 11955-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGAP1 protein levels (SeqId = 11955-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_arhgap1_protein_levels__seqid___11955-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDH1 protein levels (SeqId = 3853-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDH1 protein levels (SeqId = 3853-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Malate dehydrogenase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_mdh1_protein_levels__seqid___3853-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TPM4 protein levels (SeqId = 9863-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TPM4 protein levels (SeqId = 9863-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tropomyosin alpha-4 chain	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_tpm4_protein_levels__seqid___9863-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DBI protein levels (SeqId = 16919-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DBI protein levels (SeqId = 16919-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-CoA-binding protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_dbi_protein_levels__seqid___16919-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CNPY3 protein levels (SeqId = 17327-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CNPY3 protein levels (SeqId = 17327-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein canopy homolog 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_cnpy3_protein_levels__seqid___17327-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB2A protein levels (SeqId = 16857-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB2A protein levels (SeqId = 16857-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-2A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_rab2a_protein_levels__seqid___16857-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MRPL21 protein levels (SeqId = 8942-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MRPL21 protein levels (SeqId = 8942-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 39S ribosomal protein L21, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_mrpl21_protein_levels__seqid___8942-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HBQ1 protein levels (SeqId = 18198-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HBQ1 protein levels (SeqId = 18198-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hemoglobin subunit theta-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_hbq1_protein_levels__seqid___18198-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSK protein levels (SeqId = 3363-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSK protein levels (SeqId = 3363-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase CSK	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_csk_protein_levels__seqid___3363-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C6orf89 protein levels (SeqId = 10885-36)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C6orf89 protein levels (SeqId = 10885-36)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bombesin receptor-activated protein C6orf89	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_c6orf89_protein_levels__seqid___10885-36__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNX5 protein levels (SeqId = 18327-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNX5 protein levels (SeqId = 18327-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sorting nexin-5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_snx5_protein_levels__seqid___18327-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CRYBB1 protein levels (SeqId = 17751-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRYBB1 protein levels (SeqId = 17751-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-crystallin B1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_crybb1_protein_levels__seqid___17751-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ERP44 protein levels (SeqId = 6064-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ERP44 protein levels (SeqId = 6064-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endoplasmic reticulum resident protein 44	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_erp44_protein_levels__seqid___6064-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NUTF2 protein levels (SeqId = 19219-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUTF2 protein levels (SeqId = 19219-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear transport factor 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000011	None	Gadd-DA_nutf2_protein_levels__seqid___19219-71__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	-0.0362654	0.00825114	0.0000111449	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0362152	0.00825116	0.00001146146	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0481734	0.0109763	0.00001147379	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0361937	0.00825116	0.00001159932	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.036193	0.00825116	0.00001160371	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.036163	0.00825117	0.00001179919	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.036163	0.00825117	0.00001179959	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0361575	0.00825117	0.00001183579	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0431464	0.00984844	0.00001189363	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	0.0031	None	0.000012	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.082	0.0187	0.000012	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Lung Cancer	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Lung Cancer	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18364	1	Adults (18-65y)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.02	0.00448	0.000012	None	Robert-F-Hillary_Incident_Lung_Cancer_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	CFC1 protein levels (SeqId = 3294-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CFC1 protein levels (SeqId = 3294-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cryptic protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_cfc1_protein_levels__seqid___3294-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	WWOX protein levels (SeqId = 17724-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WWOX protein levels (SeqId = 17724-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: WW domain-containing oxidoreductase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000012	None	Gadd-DA_wwox_protein_levels__seqid___17724-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZFYVE27 protein levels (SeqId = 9102-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZFYVE27 protein levels (SeqId = 9102-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protrudin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_zfyve27_protein_levels__seqid___9102-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGAP1 protein levels (SeqId = 9815-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGAP1 protein levels (SeqId = 9815-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_arhgap1_protein_levels__seqid___9815-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AP1G2 protein levels (SeqId = 12714-38)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AP1G2 protein levels (SeqId = 12714-38)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AP-1 complex subunit gamma-like 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_ap1g2_protein_levels__seqid___12714-38__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGFBP3 protein levels (SeqId = 11219-95)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGFBP3 protein levels (SeqId = 11219-95)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor-binding protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_fgfbp3_protein_levels__seqid___11219-95__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LYN protein levels (SeqId = 3381-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LYN protein levels (SeqId = 3381-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase Lyn	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_lyn_protein_levels__seqid___3381-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BTK protein levels (SeqId = 19202-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BTK protein levels (SeqId = 19202-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase BTK	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_btk_protein_levels__seqid___19202-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK1 protein levels (SeqId = 3115-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK1 protein levels (SeqId = 3115-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_mapk1_protein_levels__seqid___3115-64__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDIA3 protein levels (SeqId = 4719-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDIA3 protein levels (SeqId = 4719-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein disulfide-isomerase A3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_pdia3_protein_levels__seqid___4719-58__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNRPA protein levels (SeqId = 12678-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNRPA protein levels (SeqId = 12678-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: U1 small nuclear ribonucleoprotein A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_snrpa_protein_levels__seqid___12678-66__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PFDN5 protein levels (SeqId = 4271-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PFDN5 protein levels (SeqId = 4271-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prefoldin subunit 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_pfdn5_protein_levels__seqid___4271-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NMT2 protein levels (SeqId = 17821-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NMT2 protein levels (SeqId = 17821-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycylpeptide N-tetradecanoyltransferase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_nmt2_protein_levels__seqid___17821-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ISOC1 protein levels (SeqId = 9816-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISOC1 protein levels (SeqId = 9816-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Isochorismatase domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_isoc1_protein_levels__seqid___9816-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PEAR1 protein levels (SeqId = 8892-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PEAR1 protein levels (SeqId = 8892-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet endothelial aggregation receptor 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_pear1_protein_levels__seqid___8892-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TAGLN2 protein levels (SeqId = 11636-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TAGLN2 protein levels (SeqId = 11636-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transgelin-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_tagln2_protein_levels__seqid___11636-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAD51L3 protein levels (SeqId = 12554-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAD51L3 protein levels (SeqId = 12554-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA repair protein RAD51 homolog 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000012	None	Gadd-DA_rad51l3_protein_levels__seqid___12554-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLEC4G protein levels (SeqId = 10781-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLEC4G protein levels (SeqId = 10781-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-type lectin domain family 4 member G	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_clec4g_protein_levels__seqid___10781-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDGFD protein levels (SeqId = 17140-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDGFD protein levels (SeqId = 17140-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet-derived growth factor D	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000012	None	Gadd-DA_pdgfd_protein_levels__seqid___17140-57__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0361284	0.00825118	0.00001202864	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19858151	chr7:157200669	7	157200669	DNAJB6	North shore	0.035337	0.00807276	0.00001209834	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0368651	0.0084322	0.00001239898	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Chatziioannou A	EnviroGenomarkers project consortium	28225026	2017-02-22	Tobacco smoking	EFO_0006527, EFO_0005671, EFO_0004318	-	Table S2	DNA methylation	Current vs never smoking	Age, sex, body mass index, study centre and cell counts	M values	-	Illumina HumanMethylation450	Whole blood	-	454	2	52	Both	None	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-	-	0.0000126	-	28225026_tobacco_smoking
Karlsson Linner R	-	29086770	2017-10-31	Educational attainment	EFO_0004784	Basic model	Table S1.6b	DNA methylation	Educational attainment	Age, sex, cell counts and technical covariates	Beta values	years of schooling	Illumina HumanMethylation450	Whole blood	-	10767	27	57	Both	None	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-	-	0.0000127	-	29086770_educational_attainment_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0360295	0.00825121	0.00001270797	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0368514	0.00844277	0.00001280834	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06229455	chr7:157189721	7	157189721	DNAJB6	North shelf	0.0056	None	0.000013	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.22	0.0501	0.000013	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	JAM2 protein levels (SeqId = 2997-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	JAM2 protein levels (SeqId = 2997-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Junctional adhesion molecule B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000013	None	Gadd-DA_jam2_protein_levels__seqid___2997-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PANK3 protein levels (SeqId = 12658-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PANK3 protein levels (SeqId = 12658-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pantothenate kinase 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000013	None	Gadd-DA_pank3_protein_levels__seqid___12658-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GHRL protein levels (SeqId = 6518-85)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GHRL protein levels (SeqId = 6518-85)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Appetite-regulating hormone	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.554	0.127	0.000013	None	Gadd-DA_ghrl_protein_levels__seqid___6518-85__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FCRL4 protein levels (SeqId = 8991-115)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FCRL4 protein levels (SeqId = 8991-115)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fc receptor-like protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000013	None	Gadd-DA_fcrl4_protein_levels__seqid___8991-115__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP2R1A protein levels (SeqId = 12621-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP2R1A protein levels (SeqId = 12621-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000013	None	Gadd-DA_ppp2r1a_protein_levels__seqid___12621-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSIP1 protein levels (SeqId = 17176-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSIP1 protein levels (SeqId = 17176-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PC4 and SFRS1-interacting protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000013	None	Gadd-DA_psip1_protein_levels__seqid___17176-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C17orf78 protein levels (SeqId = 6571-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C17orf78 protein levels (SeqId = 6571-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uncharacterized protein C17orf78	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.56	0.127	0.000013	None	Gadd-DA_c17orf78_protein_levels__seqid___6571-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GCLM protein levels (SeqId = 18214-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GCLM protein levels (SeqId = 18214-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutamate--cysteine ligase regulatory subunit	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000013	None	Gadd-DA_gclm_protein_levels__seqid___18214-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KIF23 protein levels (SeqId = 5228-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIF23 protein levels (SeqId = 5228-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kinesin-like protein KIF23	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000013	None	Gadd-DA_kif23_protein_levels__seqid___5228-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPM1L protein levels (SeqId = 7187-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPM1L protein levels (SeqId = 7187-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein phosphatase 1L	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000013	None	Gadd-DA_ppm1l_protein_levels__seqid___7187-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSNK1D protein levels (SeqId = 11289-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSNK1D protein levels (SeqId = 11289-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Casein kinase I isoform delta	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.79	0.181	0.000013	None	Gadd-DA_csnk1d_protein_levels__seqid___11289-31__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0471486	0.0108151	0.00001312316	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0422021	0.00968333	0.00001320179	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	0.0359424	0.00825124	0.00001333573	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.040098	0.00921076	0.00001349582	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.0359057	0.00825125	0.00001360948	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0418699	0.00963068	0.00001385902	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.038745	0.00891391	0.00001392082	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0358613	0.00825126	0.00001394724	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.034	0.00784	0.000014	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg20245520	chr7:157185279	7	157185279	DNAJB6	Open sea	0.01	0.00223	0.000014	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Gadd DA	Generation Scotland	35945220	31/07/2022	FER protein levels (SeqId = 4220-39)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FER protein levels (SeqId = 4220-39)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase Fer	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000014	None	Gadd-DA_fer_protein_levels__seqid___4220-39__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AK1 protein levels (SeqId = 5012-67)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AK1 protein levels (SeqId = 5012-67)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adenylate kinase isoenzyme 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000014	None	Gadd-DA_ak1_protein_levels__seqid___5012-67__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMEFF1 protein levels (SeqId = 15641-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMEFF1 protein levels (SeqId = 15641-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tomoregulin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.554	0.127	0.000014	None	Gadd-DA_tmeff1_protein_levels__seqid___15641-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MANF protein levels (SeqId = 9223-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MANF protein levels (SeqId = 9223-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mesencephalic astrocyte-derived neurotrophic factor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000014	None	Gadd-DA_manf_protein_levels__seqid___9223-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHANK3 protein levels (SeqId = 13242-134)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHANK3 protein levels (SeqId = 13242-134)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SH3 and multiple ankyrin repeat domains protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.126	0.000014	None	Gadd-DA_shank3_protein_levels__seqid___13242-134__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ISCU protein levels (SeqId = 7201-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISCU protein levels (SeqId = 7201-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Iron-sulfur cluster assembly enzyme ISCU, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000014	None	Gadd-DA_iscu_protein_levels__seqid___7201-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STIP1 protein levels (SeqId = 5489-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STIP1 protein levels (SeqId = 5489-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Stress-induced-phosphoprotein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000014	None	Gadd-DA_stip1_protein_levels__seqid___5489-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FIBP protein levels (SeqId = 19169-88)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FIBP protein levels (SeqId = 19169-88)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acidic fibroblast growth factor intracellular-binding protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000014	None	Gadd-DA_fibp_protein_levels__seqid___19169-88__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IRAK4 protein levels (SeqId = 18162-167)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IRAK4 protein levels (SeqId = 18162-167)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-1 receptor-associated kinase 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000014	None	Gadd-DA_irak4_protein_levels__seqid___18162-167__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3BP2 protein levels (SeqId = 7769-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3BP2 protein levels (SeqId = 7769-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SH3 domain-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000014	None	Gadd-DA_sh3bp2_protein_levels__seqid___7769-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HGS protein levels (SeqId = 13644-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HGS protein levels (SeqId = 13644-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatocyte growth factor-regulated tyrosine kinase substrate	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.126	0.000014	None	Gadd-DA_hgs_protein_levels__seqid___13644-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL22 protein levels (SeqId = 2778-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL22 protein levels (SeqId = 2778-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-22	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000014	None	Gadd-DA_il22_protein_levels__seqid___2778-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DPYSL3 protein levels (SeqId = 12707-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPYSL3 protein levels (SeqId = 12707-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dihydropyrimidinase-related protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000014	None	Gadd-DA_dpysl3_protein_levels__seqid___12707-26__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0579218	0.0133463	0.0000143494	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.0428702	0.00988336	0.00001450042	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23768894	chr7:157140029	7	157140029	DNAJB6	Open sea	0.0357703	0.00825129	0.00001466514	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08792082	chr7:157130291	7	157130291	DNAJB6	Island	-0.00016	0.000038	0.000015	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Liver Cirrhosis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Liver Cirrhosis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14358	1	Adults (18-65y)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.012	0.0027	0.000015	None	Robert-F-Hillary_Incident_Liver_Cirrhosis_Fully-adjusted_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12577647	chr7:157178981	7	157178981	DNAJB6	Open sea	-0.002	0.00046	0.000015	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Battram T	ARIES	None	2020-08-20	C-Reactive Protein	EFO_0004458	None	None	DNA methylation	C-Reactive Protein	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mg/l	Illumina HumanMethylation450	Whole blood	None	649	1	Adults	Females	European	cg21240861	chr7:157129652	7	157129652	DNAJB6	Island	-0.086	0.02	0.000015	None	Battram-T_c-reactive_protein
Gadd DA	Generation Scotland	35945220	31/07/2022	SDSL protein levels (SeqId = 17777-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SDSL protein levels (SeqId = 17777-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine dehydratase-like	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000015	None	Gadd-DA_sdsl_protein_levels__seqid___17777-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RNF146 protein levels (SeqId = 11401-181)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RNF146 protein levels (SeqId = 11401-181)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase RNF146	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000015	None	Gadd-DA_rnf146_protein_levels__seqid___11401-181__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PIK3CA protein levels (SeqId = 3390-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIK3CA protein levels (SeqId = 3390-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform|Phosphatidylinositol 3-kinase regulatory subunit alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000015	None	Gadd-DA_pik3ca_protein_levels__seqid___3390-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNX17 protein levels (SeqId = 12845-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNX17 protein levels (SeqId = 12845-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sorting nexin-17	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000015	None	Gadd-DA_snx17_protein_levels__seqid___12845-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NFE2L1 protein levels (SeqId = 11154-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NFE2L1 protein levels (SeqId = 11154-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endoplasmic reticulum membrane sensor NFE2L1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000015	None	Gadd-DA_nfe2l1_protein_levels__seqid___11154-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FKBP7 protein levels (SeqId = 9288-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FKBP7 protein levels (SeqId = 9288-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase FKBP7	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000015	None	Gadd-DA_fkbp7_protein_levels__seqid___9288-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TOR1AIP2 protein levels (SeqId = 10553-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TOR1AIP2 protein levels (SeqId = 10553-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Torsin-1A-interacting protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000015	None	Gadd-DA_tor1aip2_protein_levels__seqid___10553-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARPP19 protein levels (SeqId = 4963-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARPP19 protein levels (SeqId = 4963-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: cAMP-regulated phosphoprotein 19	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000015	None	Gadd-DA_arpp19_protein_levels__seqid___4963-19__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg27023755	chr7:157200373	7	157200373	DNAJB6	North shore	0.0092	0.00207	0.000015	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0357177	0.0082513	0.00001509586	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0473461	0.010939	0.00001513393	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.0356927	0.00825131	0.00001530556	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0356755	0.00825132	0.00001545042	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27496299	chr7:157171202	7	157171202	DNAJB6	Open sea	0.035665	0.00825132	0.00001554004	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0477121	0.0110468	0.00001576914	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	MRPL2 protein levels (SeqId = 19132-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MRPL2 protein levels (SeqId = 19132-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 39S ribosomal protein L2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_mrpl2_protein_levels__seqid___19132-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	OOSP2 protein levels (SeqId = 7106-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	OOSP2 protein levels (SeqId = 7106-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Oocyte-secreted protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_oosp2_protein_levels__seqid___7106-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAP1LC3A protein levels (SeqId = 17781-191)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAP1LC3A protein levels (SeqId = 17781-191)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Microtubule-associated proteins 1A/1B light chain 3A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.126	0.000016	None	Gadd-DA_map1lc3a_protein_levels__seqid___17781-191__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EFHA1 protein levels (SeqId = 6226-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EFHA1 protein levels (SeqId = 6226-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium uptake protein 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_efha1_protein_levels__seqid___6226-69__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HDHD3 protein levels (SeqId = 19482-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDHD3 protein levels (SeqId = 19482-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Haloacid dehalogenase-like hydrolase domain-containing protein 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_hdhd3_protein_levels__seqid___19482-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACE2 protein levels (SeqId = 2805-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACE2 protein levels (SeqId = 2805-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Angiotensin-converting enzyme 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_ace2_protein_levels__seqid___2805-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL18RAP protein levels (SeqId = 2993-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL18RAP protein levels (SeqId = 2993-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-18 receptor accessory protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_il18rap_protein_levels__seqid___2993-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARF4 protein levels (SeqId = 18408-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARF4 protein levels (SeqId = 18408-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_arf4_protein_levels__seqid___18408-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACADM protein levels (SeqId = 17333-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACADM protein levels (SeqId = 17333-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_acadm_protein_levels__seqid___17333-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TARBP2 protein levels (SeqId = 12781-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TARBP2 protein levels (SeqId = 12781-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RISC-loading complex subunit TARBP2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_tarbp2_protein_levels__seqid___12781-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LCK protein levels (SeqId = 4560-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LCK protein levels (SeqId = 4560-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase Lck	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_lck_protein_levels__seqid___4560-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TXLNA protein levels (SeqId = 15698-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXLNA protein levels (SeqId = 15698-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-taxilin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000016	None	Gadd-DA_txlna_protein_levels__seqid___15698-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GATM protein levels (SeqId = 18188-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GATM protein levels (SeqId = 18188-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycine amidinotransferase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.66	0.154	0.000016	None	Gadd-DA_gatm_protein_levels__seqid___18188-12__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg25024001	chr7:157207074	7	157207074	DNAJB6	Island	-0.879263	0.2039	0.0000161	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0423252	0.00981058	0.00001612018	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0399719	0.00926581	0.0000161441	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0355918	0.00825134	0.0000161776	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.361209	0.0837654	0.0000162569	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.058586	0.0136094	0.00001682189	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17483	1	Adults (18-65y)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.041	0.00949	0.000017	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Basic_model
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20723414	chr7:157207071	7	157207071	DNAJB6	Island	0.00625	0.00142	0.000017	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24844815	chr7:157130686	7	157130686	DNAJB6	South shore	0.00046	0.00011	0.000017	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJC19 protein levels (SeqId = 4545-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJC19 protein levels (SeqId = 4545-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitochondrial import inner membrane translocase subunit TIM14	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000017	None	Gadd-DA_dnajc19_protein_levels__seqid___4545-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FOXM1 protein levels (SeqId = 10056-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FOXM1 protein levels (SeqId = 10056-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Forkhead box protein M1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000017	None	Gadd-DA_foxm1_protein_levels__seqid___10056-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCDC134 protein levels (SeqId = 15300-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCDC134 protein levels (SeqId = 15300-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coiled-coil domain-containing protein 134	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000017	None	Gadd-DA_ccdc134_protein_levels__seqid___15300-66__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NAP1L1 protein levels (SeqId = 13636-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAP1L1 protein levels (SeqId = 13636-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nucleosome assembly protein 1-like 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000017	None	Gadd-DA_nap1l1_protein_levels__seqid___13636-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CAND1 protein levels (SeqId = 13937-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAND1 protein levels (SeqId = 13937-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cullin-associated NEDD8-dissociated protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000017	None	Gadd-DA_cand1_protein_levels__seqid___13937-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PCBD2 protein levels (SeqId = 6899-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PCBD2 protein levels (SeqId = 6899-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pterin-4-alpha-carbinolamine dehydratase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000017	None	Gadd-DA_pcbd2_protein_levels__seqid___6899-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDLIM1 protein levels (SeqId = 11428-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDLIM1 protein levels (SeqId = 11428-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PDZ and LIM domain protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000017	None	Gadd-DA_pdlim1_protein_levels__seqid___11428-31__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0354963	0.00825137	0.00001704618	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0387213	0.00900186	0.00001707626	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0354808	0.00825137	0.00001719156	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0354559	0.00825138	0.000017427	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0478201	0.0111416	0.00001781717	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.198934	0.0463723	0.00001797004	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0083	0.0019	0.000018	-	27651444_smoking_current_vs_never_smoking
Gadd DA	Generation Scotland	35945220	31/07/2022	TAPBP protein levels (SeqId = 12378-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TAPBP protein levels (SeqId = 12378-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tapasin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000018	None	Gadd-DA_tapbp_protein_levels__seqid___12378-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APOA1BP protein levels (SeqId = 16621-77)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APOA1BP protein levels (SeqId = 16621-77)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD(P)H-hydrate epimerase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000018	None	Gadd-DA_apoa1bp_protein_levels__seqid___16621-77__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FKBP14 protein levels (SeqId = 9340-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FKBP14 protein levels (SeqId = 9340-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase FKBP14	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000018	None	Gadd-DA_fkbp14_protein_levels__seqid___9340-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLCG2 protein levels (SeqId = 10070-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLCG2 protein levels (SeqId = 10070-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000018	None	Gadd-DA_plcg2_protein_levels__seqid___10070-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GALNT11 protein levels (SeqId = 8700-325)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GALNT11 protein levels (SeqId = 8700-325)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Polypeptide N-acetylgalactosaminyltransferase 11	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000018	None	Gadd-DA_galnt11_protein_levels__seqid___8700-325__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HPRT1 protein levels (SeqId = 19290-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HPRT1 protein levels (SeqId = 19290-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hypoxanthine-guanine phosphoribosyltransferase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000018	None	Gadd-DA_hprt1_protein_levels__seqid___19290-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STMN1 protein levels (SeqId = 17367-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STMN1 protein levels (SeqId = 17367-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Stathmin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000018	None	Gadd-DA_stmn1_protein_levels__seqid___17367-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	QDPR protein levels (SeqId = 11257-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QDPR protein levels (SeqId = 11257-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dihydropteridine reductase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000018	None	Gadd-DA_qdpr_protein_levels__seqid___11257-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AGAP2 protein levels (SeqId = 14291-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AGAP2 protein levels (SeqId = 14291-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000018	None	Gadd-DA_agap2_protein_levels__seqid___14291-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PKN1 protein levels (SeqId = 12562-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PKN1 protein levels (SeqId = 12562-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase N1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000018	None	Gadd-DA_pkn1_protein_levels__seqid___12562-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DHX58 protein levels (SeqId = 14012-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DHX58 protein levels (SeqId = 14012-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable ATP-dependent RNA helicase DHX58	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.66	0.154	0.000018	None	Gadd-DA_dhx58_protein_levels__seqid___14012-17__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.113852	0.0265483	0.00001808776	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0470846	0.0109846	0.00001827221	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.0353536	0.00825141	0.0000184277	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0416855	0.00973924	0.00001879489	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	HDAC2 protein levels (SeqId = 18897-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDAC2 protein levels (SeqId = 18897-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histone deacetylase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000019	None	Gadd-DA_hdac2_protein_levels__seqid___18897-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ST13 protein levels (SeqId = 18387-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ST13 protein levels (SeqId = 18387-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hsc70-interacting protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000019	None	Gadd-DA_st13_protein_levels__seqid___18387-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	XRCC4 protein levels (SeqId = 9886-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	XRCC4 protein levels (SeqId = 9886-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA repair protein XRCC4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000019	None	Gadd-DA_xrcc4_protein_levels__seqid___9886-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	YBX1 protein levels (SeqId = 9751-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YBX1 protein levels (SeqId = 9751-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclease-sensitive element-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000019	None	Gadd-DA_ybx1_protein_levels__seqid___9751-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GAGE2D protein levels (SeqId = 18273-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GAGE2D protein levels (SeqId = 18273-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: G antigen 2D	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.544	0.127	0.000019	None	Gadd-DA_gage2d_protein_levels__seqid___18273-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLIC1 protein levels (SeqId = 5013-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLIC1 protein levels (SeqId = 5013-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chloride intracellular channel protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000019	None	Gadd-DA_clic1_protein_levels__seqid___5013-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MRPL52 protein levels (SeqId = 7123-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MRPL52 protein levels (SeqId = 7123-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 39S ribosomal protein L52, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000019	None	Gadd-DA_mrpl52_protein_levels__seqid___7123-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SCARF1 protein levels (SeqId = 5129-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SCARF1 protein levels (SeqId = 5129-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Scavenger receptor class F member 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000019	None	Gadd-DA_scarf1_protein_levels__seqid___5129-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BCL2A1 protein levels (SeqId = 3413-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BCL2A1 protein levels (SeqId = 3413-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bcl-2-related protein A1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.55	0.127	0.000019	None	Gadd-DA_bcl2a1_protein_levels__seqid___3413-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HDAC8 protein levels (SeqId = 2859-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDAC8 protein levels (SeqId = 2859-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histone deacetylase 8	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000019	None	Gadd-DA_hdac8_protein_levels__seqid___2859-69__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0580171	0.0135744	0.00001931946	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.047346	0.0110913	0.00001978192	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0384585	0.00900951	0.00001978954	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0352171	0.00825145	0.0000198476	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0352102	0.00825145	0.00001992309	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	C10orf54 protein levels (SeqId = 14123-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C10orf54 protein levels (SeqId = 14123-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: V-type immunoglobulin domain-containing suppressor of T-cell activation	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.00002	None	Gadd-DA_c10orf54_protein_levels__seqid___14123-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	METAP1 protein levels (SeqId = 3210-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	METAP1 protein levels (SeqId = 3210-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Methionine aminopeptidase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.00002	None	Gadd-DA_metap1_protein_levels__seqid___3210-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TSLP protein levels (SeqId = 3010-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TSLP protein levels (SeqId = 3010-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thymic stromal lymphopoietin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.00002	None	Gadd-DA_tslp_protein_levels__seqid___3010-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBLCP1 protein levels (SeqId = 19124-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBLCP1 protein levels (SeqId = 19124-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-like domain-containing CTD phosphatase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.00002	None	Gadd-DA_ublcp1_protein_levels__seqid___19124-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADH5 protein levels (SeqId = 11369-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADH5 protein levels (SeqId = 11369-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alcohol dehydrogenase class-3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.00002	None	Gadd-DA_adh5_protein_levels__seqid___11369-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BRICD5 protein levels (SeqId = 6612-90)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BRICD5 protein levels (SeqId = 6612-90)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BRICHOS domain-containing protein 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.00002	None	Gadd-DA_bricd5_protein_levels__seqid___6612-90__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZNRF3 protein levels (SeqId = 10390-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZNRF3 protein levels (SeqId = 10390-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase ZNRF3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.00002	None	Gadd-DA_znrf3_protein_levels__seqid___10390-21__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0351998	0.00825145	0.00002003516	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0351812	0.00825146	0.00002023929	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	-0.0351492	0.00825147	0.00002059346	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.269438	0.0633	0.0000206	None	27105112_hiv_infection_cd4_tcells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.035144	0.00825147	0.00002065105	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0465607	0.0109357	0.00002078368	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04430780	chr7:157199439	7	157199439	DNAJB6	North shelf	0.0034	None	0.000021	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	CETN3 protein levels (SeqId = 17410-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CETN3 protein levels (SeqId = 17410-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Centrin-3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000021	None	Gadd-DA_cetn3_protein_levels__seqid___17410-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ESAM protein levels (SeqId = 7841-84)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ESAM protein levels (SeqId = 7841-84)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endothelial cell-selective adhesion molecule	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000021	None	Gadd-DA_esam_protein_levels__seqid___7841-84__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZP4 protein levels (SeqId = 7766-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZP4 protein levels (SeqId = 7766-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Zona pellucida sperm-binding protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000021	None	Gadd-DA_zp4_protein_levels__seqid___7766-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PF4 protein levels (SeqId = 2697-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PF4 protein levels (SeqId = 2697-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet factor 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000021	None	Gadd-DA_pf4_protein_levels__seqid___2697-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDGFD protein levels (SeqId = 9341-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDGFD protein levels (SeqId = 9341-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet-derived growth factor D	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000021	None	Gadd-DA_pdgfd_protein_levels__seqid___9341-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EGFL6 protein levels (SeqId = 17454-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EGFL6 protein levels (SeqId = 17454-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Epidermal growth factor-like protein 6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000021	None	Gadd-DA_egfl6_protein_levels__seqid___17454-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXNA4 protein levels (SeqId = 19560-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXNA4 protein levels (SeqId = 19560-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin-A4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000021	None	Gadd-DA_plxna4_protein_levels__seqid___19560-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EHD4 protein levels (SeqId = 11421-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EHD4 protein levels (SeqId = 11421-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: EH domain-containing protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000021	None	Gadd-DA_ehd4_protein_levels__seqid___11421-10__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0351081	0.00825148	0.00002105704	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0464553	0.010924	0.00002126359	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.0350835	0.00825149	0.00002133941	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0633588	0.0149029	0.00002137153	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0350401	0.0082515	0.0000218459	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.053	0.0125	0.000022	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	HDGF protein levels (SeqId = 16758-96)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDGF protein levels (SeqId = 16758-96)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatoma-derived growth factor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000022	None	Gadd-DA_hdgf_protein_levels__seqid___16758-96__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DLG2 protein levels (SeqId = 19620-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DLG2 protein levels (SeqId = 19620-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Disks large homolog 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000022	None	Gadd-DA_dlg2_protein_levels__seqid___19620-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPARA protein levels (SeqId = 12954-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPARA protein levels (SeqId = 12954-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxisome proliferator-activated receptor alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000022	None	Gadd-DA_ppara_protein_levels__seqid___12954-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GP5 protein levels (SeqId = 7185-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GP5 protein levels (SeqId = 7185-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet glycoprotein V	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000022	None	Gadd-DA_gp5_protein_levels__seqid___7185-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF4E protein levels (SeqId = 19263-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF4E protein levels (SeqId = 19263-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 4E	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000022	None	Gadd-DA_eif4e_protein_levels__seqid___19263-147__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DCK protein levels (SeqId = 9836-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DCK protein levels (SeqId = 9836-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Deoxycytidine kinase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000022	None	Gadd-DA_dck_protein_levels__seqid___9836-20__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26860459	chr7:157199417	7	157199417	DNAJB6	North shelf	-0.00054	0.00013	0.000022	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	NOG protein levels (SeqId = 8778-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NOG protein levels (SeqId = 8778-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Noggin	774	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.52	0.122	0.000022	None	Gadd-DA_nog_protein_levels__seqid___8778-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0391829	0.00924256	0.00002254958	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0349661	0.00825152	0.00002273748	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0462937	0.010927	0.00002282943	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	0.0012	None	0.000023	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	ASCC1 protein levels (SeqId = 10647-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASCC1 protein levels (SeqId = 10647-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Activating signal cointegrator 1 complex subunit 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000023	None	Gadd-DA_ascc1_protein_levels__seqid___10647-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STARD5 protein levels (SeqId = 17383-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STARD5 protein levels (SeqId = 17383-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: StAR-related lipid transfer protein 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.538	0.127	0.000023	None	Gadd-DA_stard5_protein_levels__seqid___17383-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSME1 protein levels (SeqId = 5918-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSME1 protein levels (SeqId = 5918-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteasome activator complex subunit 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000023	None	Gadd-DA_psme1_protein_levels__seqid___5918-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS27A protein levels (SeqId = 2846-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS27A protein levels (SeqId = 2846-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-40S ribosomal protein S27a	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000023	None	Gadd-DA_rps27a_protein_levels__seqid___2846-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RSPO2 protein levels (SeqId = 4566-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RSPO2 protein levels (SeqId = 4566-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: R-spondin-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000023	None	Gadd-DA_rspo2_protein_levels__seqid___4566-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	YWHAB protein levels (SeqId = 4707-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YWHAB protein levels (SeqId = 4707-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 14-3-3 protein eta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000023	None	Gadd-DA_ywhab_protein_levels__seqid___4707-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CARS protein levels (SeqId = 14098-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CARS protein levels (SeqId = 14098-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cysteine--tRNA ligase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000023	None	Gadd-DA_cars_protein_levels__seqid___14098-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AP1S2 protein levels (SeqId = 18405-117)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AP1S2 protein levels (SeqId = 18405-117)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AP-1 complex subunit sigma-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000023	None	Gadd-DA_ap1s2_protein_levels__seqid___18405-117__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FIS1 protein levels (SeqId = 17746-77)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FIS1 protein levels (SeqId = 17746-77)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitochondrial fission 1 protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000023	None	Gadd-DA_fis1_protein_levels__seqid___17746-77__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	WFDC13 protein levels (SeqId = 9345-436)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WFDC13 protein levels (SeqId = 9345-436)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: WAP four-disulfide core domain protein 13	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000023	None	Gadd-DA_wfdc13_protein_levels__seqid___9345-436__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPPA protein levels (SeqId = 4148-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPPA protein levels (SeqId = 4148-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pappalysin-1	774	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	-1.24	0.292	0.000023	None	Gadd-DA_pappa_protein_levels__seqid___4148-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0574806	0.0135773	0.00002313889	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0377479	0.00891896	0.00002327034	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0349185	0.00825154	0.00002332808	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0462975	0.0109488	0.00002366351	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00004836	chr7:157155664	7	157155664	DNAJB6	Open sea	0.034885	0.00825155	0.00002375355	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	0.04178	0.00988415	0.00002382955	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0379947	0.00898938	0.0000238668	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0469546	0.01111	0.0000238944	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.02	0.00458	0.000024	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12910268	chr7:157185351	7	157185351	DNAJB6	Open sea	-0.00068	0.00016	0.000024	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19428573	chr7:157200793	7	157200793	DNAJB6	North shore	0.01067	0.00247	0.000024	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	LAT2 protein levels (SeqId = 5613-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LAT2 protein levels (SeqId = 5613-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Linker for activation of T-cells family member 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.536	0.127	0.000024	None	Gadd-DA_lat2_protein_levels__seqid___5613-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	USP14 protein levels (SeqId = 19189-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	USP14 protein levels (SeqId = 19189-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin carboxyl-terminal hydrolase 14	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000024	None	Gadd-DA_usp14_protein_levels__seqid___19189-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CTF1 protein levels (SeqId = 2889-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CTF1 protein levels (SeqId = 2889-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cardiotrophin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000024	None	Gadd-DA_ctf1_protein_levels__seqid___2889-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CASP10 protein levels (SeqId = 5340-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASP10 protein levels (SeqId = 5340-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Caspase-10	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000024	None	Gadd-DA_casp10_protein_levels__seqid___5340-24__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	-0.0348571	0.00825155	0.00002411278	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.038543	0.00913254	0.00002453357	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	-0.0387023	0.00917236	0.00002463743	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0348146	0.00825157	0.00002467031	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12577647	chr7:157178981	7	157178981	DNAJB6	Open sea	0.01051	0.00243	0.000025	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	MYDGF protein levels (SeqId = 9248-36)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYDGF protein levels (SeqId = 9248-36)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Myeloid-derived growth factor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000025	None	Gadd-DA_mydgf_protein_levels__seqid___9248-36__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CXCL14 protein levels (SeqId = 5730-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXCL14 protein levels (SeqId = 5730-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-X-C motif chemokine 14	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000025	None	Gadd-DA_cxcl14_protein_levels__seqid___5730-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3GLB2 protein levels (SeqId = 18222-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3GLB2 protein levels (SeqId = 18222-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endophilin-B2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.126	0.000025	None	Gadd-DA_sh3glb2_protein_levels__seqid___18222-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BAGE2 protein levels (SeqId = 6294-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BAGE2 protein levels (SeqId = 6294-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: B melanoma antigen 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000025	None	Gadd-DA_bage2_protein_levels__seqid___6294-11__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	0.034773	0.00825158	0.00002522771	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0347547	0.00825158	0.00002547662	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0347528	0.00825158	0.0000255019	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08010530	chr7:157200028	7	157200028	DNAJB6	North shelf	0.133884	0.0318049	0.00002571698	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0509186	0.012097	0.00002578289	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.0407924	0.00969554	0.00002599277	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	KDELC2 protein levels (SeqId = 8296-117)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KDELC2 protein levels (SeqId = 8296-117)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein O-glucosyltransferase 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000026	None	Gadd-DA_kdelc2_protein_levels__seqid___8296-117__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EZR protein levels (SeqId = 9753-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EZR protein levels (SeqId = 9753-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ezrin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000026	None	Gadd-DA_ezr_protein_levels__seqid___9753-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF5 protein levels (SeqId = 2612-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF5 protein levels (SeqId = 2612-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000026	None	Gadd-DA_eif5_protein_levels__seqid___2612-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMH protein levels (SeqId = 3373-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMH protein levels (SeqId = 3373-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme H	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.529	0.126	0.000026	None	Gadd-DA_gzmh_protein_levels__seqid___3373-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZPLD1 protein levels (SeqId = 5590-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZPLD1 protein levels (SeqId = 5590-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Zona pellucida-like domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.536	0.127	0.000026	None	Gadd-DA_zpld1_protein_levels__seqid___5590-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LYZL2 protein levels (SeqId = 6377-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LYZL2 protein levels (SeqId = 6377-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lysozyme-like protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000026	None	Gadd-DA_lyzl2_protein_levels__seqid___6377-54__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UXS1 protein levels (SeqId = 8258-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UXS1 protein levels (SeqId = 8258-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UDP-glucuronic acid decarboxylase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000026	None	Gadd-DA_uxs1_protein_levels__seqid___8258-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PEBP1 protein levels (SeqId = 4276-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PEBP1 protein levels (SeqId = 4276-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylethanolamine-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000026	None	Gadd-DA_pebp1_protein_levels__seqid___4276-10__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.152384	0.0362244	0.00002604724	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0347026	0.0082516	0.00002619859	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0415604	0.0098835	0.00002625941	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0468443	0.0111402	0.00002626669	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	-0.257658	0.0613145	0.00002656214	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0407458	0.00969603	0.00002657669	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24185680	chr7:157171288	7	157171288	DNAJB6	Open sea	-0.0346699	0.00825161	0.00002666094	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	None	None	0.000027	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg19858151	chr7:157200669	7	157200669	DNAJB6	North shore	-0.0028	0.00064	0.000027	None	33564054_Kashima-K_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	POLE3 protein levels (SeqId = 19170-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	POLE3 protein levels (SeqId = 19170-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA polymerase epsilon subunit 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000027	None	Gadd-DA_pole3_protein_levels__seqid___19170-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C12orf10 protein levels (SeqId = 8303-102)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C12orf10 protein levels (SeqId = 8303-102)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UPF0160 protein MYG1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000027	None	Gadd-DA_c12orf10_protein_levels__seqid___8303-102__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ATG5 protein levels (SeqId = 12597-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ATG5 protein levels (SeqId = 12597-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Autophagy protein 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.54	0.127	0.000027	None	Gadd-DA_atg5_protein_levels__seqid___12597-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VAV3 protein levels (SeqId = 9830-109)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VAV3 protein levels (SeqId = 9830-109)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Guanine nucleotide exchange factor VAV3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000027	None	Gadd-DA_vav3_protein_levels__seqid___9830-109__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CHP1 protein levels (SeqId = 12458-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHP1 protein levels (SeqId = 12458-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcineurin B homologous protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000027	None	Gadd-DA_chp1_protein_levels__seqid___12458-79__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COMMD7 protein levels (SeqId = 2823-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COMMD7 protein levels (SeqId = 2823-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: COMM domain-containing protein 7	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000027	None	Gadd-DA_commd7_protein_levels__seqid___2823-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RFXAP protein levels (SeqId = 12726-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RFXAP protein levels (SeqId = 12726-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Regulatory factor X-associated protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000027	None	Gadd-DA_rfxap_protein_levels__seqid___12726-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TRDMT1 protein levels (SeqId = 12635-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TRDMT1 protein levels (SeqId = 12635-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: tRNA (cytosine(38)-C(5))-methyltransferase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000027	None	Gadd-DA_trdmt1_protein_levels__seqid___12635-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFAIP8 protein levels (SeqId = 12563-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFAIP8 protein levels (SeqId = 12563-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor alpha-induced protein 8	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000027	None	Gadd-DA_tnfaip8_protein_levels__seqid___12563-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RNGTT protein levels (SeqId = 12847-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RNGTT protein levels (SeqId = 12847-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: mRNA-capping enzyme	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000027	None	Gadd-DA_rngtt_protein_levels__seqid___12847-27__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0459866	0.0109525	0.00002700077	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_2
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg19858151	chr7:157200669	7	157200669	DNAJB6	North shore	-0.00039101	9.28e-05	0.0000275	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.0447044	0.0106597	0.00002759408	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0345821	0.00825163	0.00002794254	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NAT14 protein levels (SeqId = 11120-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAT14 protein levels (SeqId = 11120-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-acetyltransferase 14	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000028	None	Gadd-DA_nat14_protein_levels__seqid___11120-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CUL3 protein levels (SeqId = 10045-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CUL3 protein levels (SeqId = 10045-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cullin-3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000028	None	Gadd-DA_cul3_protein_levels__seqid___10045-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSP90B1 protein levels (SeqId = 6393-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSP90B1 protein levels (SeqId = 6393-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endoplasmin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000028	None	Gadd-DA_hsp90b1_protein_levels__seqid___6393-63__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJC30 protein levels (SeqId = 7866-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJC30 protein levels (SeqId = 7866-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily C member 30, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000028	None	Gadd-DA_dnajc30_protein_levels__seqid___7866-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARL6 protein levels (SeqId = 18415-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARL6 protein levels (SeqId = 18415-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor-like protein 6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000028	None	Gadd-DA_arl6_protein_levels__seqid___18415-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VPS4B protein levels (SeqId = 12668-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VPS4B protein levels (SeqId = 12668-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vacuolar protein sorting-associated protein 4B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.13	0.000028	None	Gadd-DA_vps4b_protein_levels__seqid___12668-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMEM59L protein levels (SeqId = 9959-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMEM59L protein levels (SeqId = 9959-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transmembrane protein 59-like	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000028	None	Gadd-DA_tmem59l_protein_levels__seqid___9959-60__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg17833937	chr7:157142583	7	157142583	DNAJB6	Open sea	-0.8473	0.2024	0.0000284	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	0.0345377	0.00825165	0.0000286125	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMK protein levels (SeqId = 9545-156)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMK protein levels (SeqId = 9545-156)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme K	774	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.77	0.184	0.000029	None	Gadd-DA_gzmk_protein_levels__seqid___9545-156__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPM protein levels (SeqId = 12783-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPM protein levels (SeqId = 12783-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein M	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000029	None	Gadd-DA_hnrnpm_protein_levels__seqid___12783-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADPRHL2 protein levels (SeqId = 17332-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADPRHL2 protein levels (SeqId = 17332-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribose glycohydrolase ARH3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000029	None	Gadd-DA_adprhl2_protein_levels__seqid___17332-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APAF1 protein levels (SeqId = 13583-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APAF1 protein levels (SeqId = 13583-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Apoptotic protease-activating factor 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000029	None	Gadd-DA_apaf1_protein_levels__seqid___13583-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRR16 protein levels (SeqId = 10621-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRR16 protein levels (SeqId = 10621-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein Largen	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000029	None	Gadd-DA_prr16_protein_levels__seqid___10621-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSMD2 protein levels (SeqId = 9971-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSMD2 protein levels (SeqId = 9971-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: CUB and sushi domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000029	None	Gadd-DA_csmd2_protein_levels__seqid___9971-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GMFG protein levels (SeqId = 13062-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GMFG protein levels (SeqId = 13062-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glia maturation factor gamma	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000029	None	Gadd-DA_gmfg_protein_levels__seqid___13062-4__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.00014	None	0.000029	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.038763	0.00926975	0.00002910649	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24185680	chr7:157171288	7	157171288	DNAJB6	Open sea	-0.0344994	0.00825166	0.000029203	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	-0.0344767	0.00825166	0.00002955822	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.045452	0.01088	0.00002963476	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.034463	0.00825167	0.00002977615	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CCL7 protein levels (SeqId = 4886-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCL7 protein levels (SeqId = 4886-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-C motif chemokine 7	774	1	Adults (18-65 years)	Both	European	cg06229455	chr7:157189721	7	157189721	DNAJB6	North shelf	-0.72	0.172	0.00003	None	Gadd-DA_ccl7_protein_levels__seqid___4886-3__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Osteoarthritis (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Osteoarthritis (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18060	1	Adults (18-65y)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.098	0.0235	0.00003	None	Robert-F-Hillary_Prevalent_Osteoarthritis_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	TXNL4B protein levels (SeqId = 15316-262)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXNL4B protein levels (SeqId = 15316-262)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin-like protein 4B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.00003	None	Gadd-DA_txnl4b_protein_levels__seqid___15316-262__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PNPO protein levels (SeqId = 17804-102)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PNPO protein levels (SeqId = 17804-102)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pyridoxine-5'-phosphate oxidase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.00003	None	Gadd-DA_pnpo_protein_levels__seqid___17804-102__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ELK1 protein levels (SeqId = 10006-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ELK1 protein levels (SeqId = 10006-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ETS domain-containing protein Elk-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.00003	None	Gadd-DA_elk1_protein_levels__seqid___10006-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSME2 protein levels (SeqId = 17694-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSME2 protein levels (SeqId = 17694-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteasome activator complex subunit 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.00003	None	Gadd-DA_psme2_protein_levels__seqid___17694-32__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0344224	0.00825168	0.00003042596	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0344204	0.00825168	0.00003045862	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.056247	0.0134864	0.00003054988	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.110917	0.0266099	0.00003084309	None	39706196_Hannah-M.-Smith_body_fat_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05726556	chr7:157203124	7	157203124	DNAJB6	Island	-0.161514	0.038754	0.00003091532	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	QPCT protein levels (SeqId = 7849-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QPCT protein levels (SeqId = 7849-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutaminyl-peptide cyclotransferase	774	1	Adults (18-65 years)	Both	European	cg22412150	chr7:157208980	7	157208980	DNAJB6	Island	0.58	0.139	0.000031	None	Gadd-DA_qpct_protein_levels__seqid___7849-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RRAS2 protein levels (SeqId = 12361-102)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RRAS2 protein levels (SeqId = 12361-102)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein R-Ras2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000031	None	Gadd-DA_rras2_protein_levels__seqid___12361-102__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BMX protein levels (SeqId = 3414-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BMX protein levels (SeqId = 3414-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytoplasmic tyrosine-protein kinase BMX	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000031	None	Gadd-DA_bmx_protein_levels__seqid___3414-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HRAS protein levels (SeqId = 18900-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HRAS protein levels (SeqId = 18900-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GTPase HRas	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000031	None	Gadd-DA_hras_protein_levels__seqid___18900-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK12 protein levels (SeqId = 5005-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK12 protein levels (SeqId = 5005-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 12	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000031	None	Gadd-DA_mapk12_protein_levels__seqid___5005-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPIL1 protein levels (SeqId = 9884-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPIL1 protein levels (SeqId = 9884-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase-like 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000031	None	Gadd-DA_ppil1_protein_levels__seqid___9884-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPOCK3 protein levels (SeqId = 9906-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPOCK3 protein levels (SeqId = 9906-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Testican-3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000031	None	Gadd-DA_spock3_protein_levels__seqid___9906-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APBB1 protein levels (SeqId = 12822-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APBB1 protein levels (SeqId = 12822-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Amyloid-beta A4 precursor protein-binding family B member 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000031	None	Gadd-DA_apbb1_protein_levels__seqid___12822-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FKBP4 protein levels (SeqId = 17722-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FKBP4 protein levels (SeqId = 17722-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase FKBP4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000031	None	Gadd-DA_fkbp4_protein_levels__seqid___17722-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0351281	0.00843925	0.00003166281	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0343353	0.0082517	0.00003186652	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01766193	chr7:157202248	7	157202248	DNAJB6	North shore	0.0051	None	0.000032	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	XRCC6 protein levels (SeqId = 2835-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	XRCC6 protein levels (SeqId = 2835-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: X-ray repair cross-complementing protein 6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000032	None	Gadd-DA_xrcc6_protein_levels__seqid___2835-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF2B1 protein levels (SeqId = 10080-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF2B1 protein levels (SeqId = 10080-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Translation initiation factor eIF-2B subunit alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000032	None	Gadd-DA_eif2b1_protein_levels__seqid___10080-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMOD2 protein levels (SeqId = 12853-112)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMOD2 protein levels (SeqId = 12853-112)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tropomodulin-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.523	0.126	0.000032	None	Gadd-DA_tmod2_protein_levels__seqid___12853-112__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMPO protein levels (SeqId = 8265-225)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMPO protein levels (SeqId = 8265-225)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lamina-associated polypeptide 2, isoforms beta/gamma	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000032	None	Gadd-DA_tmpo_protein_levels__seqid___8265-225__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ATOX1 protein levels (SeqId = 19233-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ATOX1 protein levels (SeqId = 19233-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Copper transport protein ATOX1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000032	None	Gadd-DA_atox1_protein_levels__seqid___19233-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GHRH protein levels (SeqId = 16293-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GHRH protein levels (SeqId = 16293-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Somatoliberin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000032	None	Gadd-DA_ghrh_protein_levels__seqid___16293-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PFDN2 protein levels (SeqId = 19243-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PFDN2 protein levels (SeqId = 19243-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prefoldin subunit 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000032	None	Gadd-DA_pfdn2_protein_levels__seqid___19243-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	-0.0343081	0.00825171	0.00003233062	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05641778	chr7:157194536	7	157194536	DNAJB6	South shore	-0.0343063	0.00825171	0.00003236128	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	-0.0342924	0.00825172	0.0000325998	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	0.034275	0.00825172	0.00003290203	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0342691	0.00825172	0.00003300563	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0366505	0.00882723	0.00003314676	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0342536	0.00825173	0.00003327735	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Total cholesterol in chylomicrons and extremely large VLDL	EFO_0004574	None	None	DNA methylation	Total cholesterol in chylomicrons and extremely large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	661	1	Adults	Females	European	cg12577647	chr7:157178981	7	157178981	DNAJB6	Open sea	-42	10.1	0.000034	None	Battram-T_total_cholesterol_in_chylomicrons_and_extremely_large_vldl
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13515783	chr7:157201622	7	157201622	DNAJB6	North shore	0.00098	None	0.000034	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB22A protein levels (SeqId = 12408-333)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB22A protein levels (SeqId = 12408-333)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-22A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.528	0.127	0.000034	None	Gadd-DA_rab22a_protein_levels__seqid___12408-333__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.034212	0.00825174	0.00003401752	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.051253	0.0123631	0.00003407589	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0562946	0.0135841	0.00003430041	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.00334	0.00081	0.000035	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	EPB41 protein levels (SeqId = 4706-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPB41 protein levels (SeqId = 4706-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein 4.1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000035	None	Gadd-DA_epb41_protein_levels__seqid___4706-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PYGL protein levels (SeqId = 11441-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PYGL protein levels (SeqId = 11441-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycogen phosphorylase, liver form	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000035	None	Gadd-DA_pygl_protein_levels__seqid___11441-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RIPK2 protein levels (SeqId = 8970-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RIPK2 protein levels (SeqId = 8970-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Receptor-interacting serine/threonine-protein kinase 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000035	None	Gadd-DA_ripk2_protein_levels__seqid___8970-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0455401	0.0110017	0.00003502255	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0341528	0.00825175	0.00003509943	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg09903872	chr7:157129451	7	157129451	DNAJB6	Island	-0.144149	0.0348	0.0000351	-	27105112_hiv_infection_neutrophils
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.0472973	0.0114302	0.00003524185	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0341325	0.00825176	0.00003547802	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.034126	0.00825176	0.0000356	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.0352372	0.00852049	0.0000356023	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04211	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04211	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0341235	0.00825176	0.00003564758	P04211	41361833_Josephine_Robertson_P04211_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0341222	0.00825176	0.0000356716	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	0.0399657	0.00966693	0.00003580695	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0459053	0.0111039	0.0000358254	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	HMGB1 protein levels (SeqId = 2524-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HMGB1 protein levels (SeqId = 2524-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: High mobility group protein B1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000036	None	Gadd-DA_hmgb1_protein_levels__seqid___2524-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CTGF protein levels (SeqId = 2975-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CTGF protein levels (SeqId = 2975-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Connective tissue growth factor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000036	None	Gadd-DA_ctgf_protein_levels__seqid___2975-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0340944	0.00825177	0.00003619826	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12910268	chr7:157185351	7	157185351	DNAJB6	Open sea	-0.0340717	0.00825178	0.00003663489	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	-0.99	0.24	0.000037	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06416110	chr7:157190100	7	157190100	DNAJB6	North shelf	0.0032	None	0.000037	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25024001	chr7:157207074	7	157207074	DNAJB6	Island	0.00066	None	0.000037	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	RCL protein levels (SeqId = 17785-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RCL protein levels (SeqId = 17785-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000037	None	Gadd-DA_rcl_protein_levels__seqid___17785-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EDC4 protein levels (SeqId = 13066-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EDC4 protein levels (SeqId = 13066-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Enhancer of mRNA-decapping protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.53	0.127	0.000037	None	Gadd-DA_edc4_protein_levels__seqid___13066-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HERC5 protein levels (SeqId = 12934-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HERC5 protein levels (SeqId = 12934-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ISG15--protein ligase HERC5	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.635	0.154	0.000037	None	Gadd-DA_herc5_protein_levels__seqid___12934-1__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg08620789	chr7:157129638	7	157129638	DNAJB6	Island	-1.021396	0.2478	0.0000375	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0340202	0.00825179	0.00003764033	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0452403	0.0109738	0.0000376714	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0400096	0.00970765	0.00003785621	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	BAG2 protein levels (SeqId = 19228-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BAG2 protein levels (SeqId = 19228-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BAG family molecular chaperone regulator 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.522	0.127	0.000038	None	Gadd-DA_bag2_protein_levels__seqid___19228-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ASRGL1 protein levels (SeqId = 18313-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASRGL1 protein levels (SeqId = 18313-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Isoaspartyl peptidase/L-asparaginase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000038	None	Gadd-DA_asrgl1_protein_levels__seqid___18313-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BCL2L2 protein levels (SeqId = 13097-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BCL2L2 protein levels (SeqId = 13097-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bcl-2-like protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.524	0.127	0.000038	None	Gadd-DA_bcl2l2_protein_levels__seqid___13097-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HRASLS2 protein levels (SeqId = 7822-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HRASLS2 protein levels (SeqId = 7822-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: HRAS-like suppressor 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000038	None	Gadd-DA_hrasls2_protein_levels__seqid___7822-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SSU72 protein levels (SeqId = 13566-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SSU72 protein levels (SeqId = 13566-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RNA polymerase II subunit A C-terminal domain phosphatase SSU72	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000038	None	Gadd-DA_ssu72_protein_levels__seqid___13566-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AGO1 protein levels (SeqId = 15312-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AGO1 protein levels (SeqId = 15312-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein argonaute-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000038	None	Gadd-DA_ago1_protein_levels__seqid___15312-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GATM protein levels (SeqId = 18188-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GATM protein levels (SeqId = 18188-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycine amidinotransferase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000038	None	Gadd-DA_gatm_protein_levels__seqid___18188-12__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0407341	0.00988974	0.00003829131	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.033968	0.00825181	0.0000386884	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00004836	chr7:157155664	7	157155664	DNAJB6	Open sea	-0.0381593	0.00927049	0.00003872661	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0558221	0.0135632	0.00003881284	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	-0.0446586	0.0108528	0.00003894063	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.00075	0.00018	0.000039	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Gadd DA	Generation Scotland	35945220	31/07/2022	COL4A3BP protein levels (SeqId = 13535-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COL4A3BP protein levels (SeqId = 13535-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen type IV alpha-3-binding protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000039	None	Gadd-DA_col4a3bp_protein_levels__seqid___13535-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GPX7 protein levels (SeqId = 8345-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GPX7 protein levels (SeqId = 8345-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione peroxidase 7	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000039	None	Gadd-DA_gpx7_protein_levels__seqid___8345-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLINT1 protein levels (SeqId = 11659-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLINT1 protein levels (SeqId = 11659-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Clathrin interactor 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.126	0.000039	None	Gadd-DA_clint1_protein_levels__seqid___11659-31__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0369433	0.00898172	0.00003923999	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.036055	0.00876622	0.00003927681	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0339387	0.00825182	0.00003928874	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0393038	0.00956361	0.00003982837	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	KIR2DS2 protein levels (SeqId = 10428-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIR2DS2 protein levels (SeqId = 10428-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Killer cell immunoglobulin-like receptor 2DS2	774	1	Adults (18-65 years)	Both	European	cg14567287	chr7:157129156	7	157129156	DNAJB6	Island	0.65	0.158	0.00004	None	Gadd-DA_kir2ds2_protein_levels__seqid___10428-1__somascan_protein_measurement
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg15248935	chr7:157180055	7	157180055	DNAJB6	Open sea	-0.00146	0.00036	0.00004	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	IL7R protein levels (SeqId = 5089-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL7R protein levels (SeqId = 5089-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-7 receptor subunit alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.00004	None	Gadd-DA_il7r_protein_levels__seqid___5089-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DCTD protein levels (SeqId = 17756-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DCTD protein levels (SeqId = 17756-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Deoxycytidylate deaminase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.00004	None	Gadd-DA_dctd_protein_levels__seqid___17756-69__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZFAND5 protein levels (SeqId = 18317-111)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZFAND5 protein levels (SeqId = 18317-111)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AN1-type zinc finger protein 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.00004	None	Gadd-DA_zfand5_protein_levels__seqid___18317-111__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAD1 protein levels (SeqId = 12670-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAD1 protein levels (SeqId = 12670-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cell cycle checkpoint protein RAD1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.00004	None	Gadd-DA_rad1_protein_levels__seqid___12670-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AKR1B1 protein levels (SeqId = 16606-85)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKR1B1 protein levels (SeqId = 16606-85)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aldo-keto reductase family 1 member B1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.00004	None	Gadd-DA_akr1b1_protein_levels__seqid___16606-85__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLEC2B protein levels (SeqId = 7786-83)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLEC2B protein levels (SeqId = 7786-83)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-type lectin domain family 2 member B	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.63	0.153	0.00004	None	Gadd-DA_clec2b_protein_levels__seqid___7786-83__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg12910268	chr7:157185351	7	157185351	DNAJB6	Open sea	-0.169087	0.041156	0.00004001566	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	-0.0376371	0.00916499	0.00004036775	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0338845	0.00825183	0.00004042323	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FHIT protein levels (SeqId = 9826-135)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FHIT protein levels (SeqId = 9826-135)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bis(5'-adenosyl)-triphosphatase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000041	None	Gadd-DA_fhit_protein_levels__seqid___9826-135__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LMAN2L protein levels (SeqId = 8013-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LMAN2L protein levels (SeqId = 8013-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: VIP36-like protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000041	None	Gadd-DA_lman2l_protein_levels__seqid___8013-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PECR protein levels (SeqId = 17776-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PECR protein levels (SeqId = 17776-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxisomal trans-2-enoyl-CoA reductase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000041	None	Gadd-DA_pecr_protein_levels__seqid___17776-15__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg27496299	chr7:157171202	7	157171202	DNAJB6	Open sea	0.0055	0.00131	0.000041	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0338517	0.00825184	0.00004112348	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0449005	0.0109495	0.00004141259	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0436063	0.0106362	0.00004157263	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0371329	0.00906161	0.00004192883	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0398089	0.00971518	0.0000419712	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PITPNA protein levels (SeqId = 9934-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PITPNA protein levels (SeqId = 9934-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylinositol transfer protein alpha isoform	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000042	None	Gadd-DA_pitpna_protein_levels__seqid___9934-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FMR1 protein levels (SeqId = 7713-102)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FMR1 protein levels (SeqId = 7713-102)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Synaptic functional regulator FMR1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000042	None	Gadd-DA_fmr1_protein_levels__seqid___7713-102__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CMA1 protein levels (SeqId = 3423-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CMA1 protein levels (SeqId = 3423-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chymase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000042	None	Gadd-DA_cma1_protein_levels__seqid___3423-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AP4M1 protein levels (SeqId = 10076-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AP4M1 protein levels (SeqId = 10076-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AP-4 complex subunit mu-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000042	None	Gadd-DA_ap4m1_protein_levels__seqid___10076-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FLRT3 protein levels (SeqId = 9128-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FLRT3 protein levels (SeqId = 9128-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leucine-rich repeat transmembrane protein FLRT3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000042	None	Gadd-DA_flrt3_protein_levels__seqid___9128-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TXNDC5 protein levels (SeqId = 11212-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXNDC5 protein levels (SeqId = 11212-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin domain-containing protein 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.522	0.127	0.000042	None	Gadd-DA_txndc5_protein_levels__seqid___11212-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HEXIM2 protein levels (SeqId = 14205-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HEXIM2 protein levels (SeqId = 14205-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein HEXIM2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000042	None	Gadd-DA_hexim2_protein_levels__seqid___14205-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TREML1 protein levels (SeqId = 9329-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TREML1 protein levels (SeqId = 9329-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Trem-like transcript 1 protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000042	None	Gadd-DA_treml1_protein_levels__seqid___9329-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0345465	0.00843293	0.00004214785	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Gervin K	-	28785368	2017-08-02	Attention deficit hyperactivity disorder	EFO_0003888	Long-term prenatal exposure to paracetamol versus sporadic prenatal exposure to paracetamol	Table S2	DNA methylation	Long-term prenatal exposure to paracetamol in children with ADHD versus sporadic prenatal exposure to paracetamol in children with ADHD	Sex, smoking, maternal age, gestational age, cell counts and technical covariates	M values	-	Illumina HumanMethylation450	Cord blood	-	96	1	0	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-	-	0.0000423	-	28785368_attention_deficit_hyperactivity_disorder_longterm_prenatal_exposure_to_paracetamol_versus_sporadic_prenatal_exposure_to_paracetamol
Gadd DA	Generation Scotland	35945220	31/07/2022	RARRES1 protein levels (SeqId = 8398-277)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RARRES1 protein levels (SeqId = 8398-277)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Retinoic acid receptor responder protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000043	None	Gadd-DA_rarres1_protein_levels__seqid___8398-277__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCPG1 protein levels (SeqId = 8889-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCPG1 protein levels (SeqId = 8889-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cell cycle progression protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000043	None	Gadd-DA_ccpg1_protein_levels__seqid___8889-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDC2 protein levels (SeqId = 3422-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDC2 protein levels (SeqId = 3422-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cyclin-dependent kinase 1|G2/mitotic-specific cyclin-B1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.519	0.127	0.000043	None	Gadd-DA_cdc2_protein_levels__seqid___3422-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0451222	0.0110273	0.00004302355	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg19858151	chr7:157200669	7	157200669	DNAJB6	North shore	-0.177304	0.0433497	0.000043305	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	0.0337446	0.00825187	0.00004349274	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg19428573	chr7:157200793	7	157200793	DNAJB6	North shore	0.037	0.00915	0.000044	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	KLRC4 protein levels (SeqId = 10552-88)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLRC4 protein levels (SeqId = 10552-88)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NKG2-F type II integral membrane protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000044	None	Gadd-DA_klrc4_protein_levels__seqid___10552-88__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	JMJD6 protein levels (SeqId = 18322-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	JMJD6 protein levels (SeqId = 18322-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000044	None	Gadd-DA_jmjd6_protein_levels__seqid___18322-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CASP2 protein levels (SeqId = 4904-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASP2 protein levels (SeqId = 4904-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Caspase-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000044	None	Gadd-DA_casp2_protein_levels__seqid___4904-7__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07048143	chr7:157199479	7	157199479	DNAJB6	North shelf	0.176315	0.0431498	0.0000440625	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0372205	0.00911443	0.00004456139	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Trunk bone mineral content	EFO_0007621	None	None	DNA methylation	Trunk bone mineral content	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	706	1	Adults	Females	European	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	-0.00042	0.0001	0.000045	None	Battram-T_trunk_bone_mineral_content
Battram T	ARIES	None	2020-08-20	Trunk bone mass	EFO_0004512	None	None	DNA methylation	Trunk bone mass	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	706	1	Adults	Females	European	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	-0.00042	0.0001	0.000045	None	Battram-T_trunk_bone_mass
Battram T	ARIES	None	2020-08-20	Concentration of chylomicrons and extremely large VLDL particles	EFO_0008596	None	None	DNA methylation	Concentration of chylomicrons and extremely large VLDL particles	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mol/l	Illumina HumanMethylation450	Whole blood	None	623	1	Adults	Females	European	cg12577647	chr7:157178981	7	157178981	DNAJB6	Open sea	-1800000000	430000000	0.000045	None	Battram-T_concentration_of_chylomicrons_and_extremely_large_vldl_particles
Gadd DA	Generation Scotland	35945220	31/07/2022	EEF1B2 protein levels (SeqId = 5882-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EEF1B2 protein levels (SeqId = 5882-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Elongation factor 1-beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000045	None	Gadd-DA_eef1b2_protein_levels__seqid___5882-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MMEL1 protein levels (SeqId = 3627-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MMEL1 protein levels (SeqId = 3627-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Membrane metallo-endopeptidase-like 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000045	None	Gadd-DA_mmel1_protein_levels__seqid___3627-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TUFT1 protein levels (SeqId = 5690-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TUFT1 protein levels (SeqId = 5690-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tuftelin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000045	None	Gadd-DA_tuft1_protein_levels__seqid___5690-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NAB2 protein levels (SeqId = 13680-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAB2 protein levels (SeqId = 13680-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NGFI-A-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000045	None	Gadd-DA_nab2_protein_levels__seqid___13680-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08010530	chr7:157200028	7	157200028	DNAJB6	North shelf	0.0339628	0.0083252	0.0000453689	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0336486	0.0082519	0.00004572651	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	0.0336407	0.0082519	0.00004591566	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0554816	0.0136096	0.00004592747	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CYB5R3 protein levels (SeqId = 7215-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CYB5R3 protein levels (SeqId = 7215-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NADH-cytochrome b5 reductase 3	774	1	Adults (18-65 years)	Both	European	cg18753341	chr7:157202405	7	157202405	DNAJB6	Island	0.6	0.148	0.000046	None	Gadd-DA_cyb5r3_protein_levels__seqid___7215-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STX4 protein levels (SeqId = 10668-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STX4 protein levels (SeqId = 10668-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Syntaxin-4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.126	0.000046	None	Gadd-DA_stx4_protein_levels__seqid___10668-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSD17B11 protein levels (SeqId = 17397-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSD17B11 protein levels (SeqId = 17397-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Estradiol 17-beta-dehydrogenase 11	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.518	0.127	0.000046	None	Gadd-DA_hsd17b11_protein_levels__seqid___17397-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRB14 protein levels (SeqId = 13628-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRB14 protein levels (SeqId = 13628-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Growth factor receptor-bound protein 14	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000046	None	Gadd-DA_grb14_protein_levels__seqid___13628-58__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ING1 protein levels (SeqId = 3888-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ING1 protein levels (SeqId = 3888-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inhibitor of growth protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000046	None	Gadd-DA_ing1_protein_levels__seqid___3888-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CHGB protein levels (SeqId = 8235-48)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHGB protein levels (SeqId = 8235-48)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Secretogranin-1	774	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.5	0.122	0.000046	None	Gadd-DA_chgb_protein_levels__seqid___8235-48__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03996020	chr7:157180124	7	157180124	DNAJB6	Open sea	0.0336192	0.0082519	0.00004643296	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0434789	0.0106773	0.0000468395	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0447731	0.0109973	0.00004699792	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJC16 protein levels (SeqId = 10454-99)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJC16 protein levels (SeqId = 10454-99)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily C member 16	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000047	None	Gadd-DA_dnajc16_protein_levels__seqid___10454-99__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFSF15 protein levels (SeqId = 2968-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFSF15 protein levels (SeqId = 2968-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor ligand superfamily member 15	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.13	0.000047	None	Gadd-DA_tnfsf15_protein_levels__seqid___2968-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	JUND protein levels (SeqId = 19602-36)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	JUND protein levels (SeqId = 19602-36)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription factor jun-D	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000047	None	Gadd-DA_jund_protein_levels__seqid___19602-36__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CNOT1 protein levels (SeqId = 13482-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CNOT1 protein levels (SeqId = 13482-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: CCR4-NOT transcription complex subunit 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000047	None	Gadd-DA_cnot1_protein_levels__seqid___13482-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAU1 protein levels (SeqId = 12471-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAU1 protein levels (SeqId = 12471-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Double-stranded RNA-binding protein Staufen homolog 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.13	0.000047	None	Gadd-DA_stau1_protein_levels__seqid___12471-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CETN2 protein levels (SeqId = 13078-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CETN2 protein levels (SeqId = 13078-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Centrin-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000047	None	Gadd-DA_cetn2_protein_levels__seqid___13078-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	0.0335942	0.00825191	0.00004704066	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0335661	0.00825192	0.00004773318	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NFKBIB protein levels (SeqId = 17387-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NFKBIB protein levels (SeqId = 17387-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NF-kappa-B inhibitor beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000048	None	Gadd-DA_nfkbib_protein_levels__seqid___17387-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB14 protein levels (SeqId = 14283-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB14 protein levels (SeqId = 14283-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-14	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.736	0.181	0.000048	None	Gadd-DA_rab14_protein_levels__seqid___14283-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRG3 protein levels (SeqId = 9015-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRG3 protein levels (SeqId = 9015-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteoglycan 3	774	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	-1.19	0.293	0.000048	None	Gadd-DA_prg3_protein_levels__seqid___9015-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	POR protein levels (SeqId = 2731-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	POR protein levels (SeqId = 2731-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NADPH--cytochrome P450 reductase	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.63	0.154	0.000048	None	Gadd-DA_por_protein_levels__seqid___2731-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.0347582	0.00854809	0.00004803654	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	TLN2 protein levels (SeqId = 14082-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TLN2 protein levels (SeqId = 14082-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Talin-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000049	None	Gadd-DA_tln2_protein_levels__seqid___14082-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPOP protein levels (SeqId = 13727-44)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPOP protein levels (SeqId = 13727-44)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Speckle-type POZ protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000049	None	Gadd-DA_spop_protein_levels__seqid___13727-44__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DEFB121 protein levels (SeqId = 5765-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DEFB121 protein levels (SeqId = 5765-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-defensin 121	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000049	None	Gadd-DA_defb121_protein_levels__seqid___5765-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COL4A3BP protein levels (SeqId = 13950-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COL4A3BP protein levels (SeqId = 13950-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen type IV alpha-3-binding protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.514	0.127	0.000049	None	Gadd-DA_col4a3bp_protein_levels__seqid___13950-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	0.0365111	0.00899304	0.00004934157	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CSNK1G2 protein levels (SeqId = 12653-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSNK1G2 protein levels (SeqId = 12653-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Casein kinase I isoform gamma-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.00005	None	Gadd-DA_csnk1g2_protein_levels__seqid___12653-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LDLR protein levels (SeqId = 13129-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LDLR protein levels (SeqId = 13129-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Low-density lipoprotein receptor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.511	0.126	0.000051	None	Gadd-DA_ldlr_protein_levels__seqid___13129-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAMDC2 protein levels (SeqId = 6119-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAMDC2 protein levels (SeqId = 6119-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000051	None	Gadd-DA_mamdc2_protein_levels__seqid___6119-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CBFB protein levels (SeqId = 10048-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBFB protein levels (SeqId = 10048-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Core-binding factor subunit beta	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000051	None	Gadd-DA_cbfb_protein_levels__seqid___10048-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GLTP protein levels (SeqId = 12513-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GLTP protein levels (SeqId = 12513-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycolipid transfer protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000051	None	Gadd-DA_gltp_protein_levels__seqid___12513-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CHFR protein levels (SeqId = 11320-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHFR protein levels (SeqId = 11320-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase CHFR	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.73	0.181	0.000051	None	Gadd-DA_chfr_protein_levels__seqid___11320-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TBPL1 protein levels (SeqId = 18434-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TBPL1 protein levels (SeqId = 18434-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: TATA box-binding protein-like protein 1	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.73	0.181	0.000051	None	Gadd-DA_tbpl1_protein_levels__seqid___18434-141__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02749	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02749	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0873378	0.0215581	0.00005120098	P02749	41361833_Josephine_Robertson_P02749_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.03342	0.00825196	0.00005149298	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.035899	0.00886812	0.00005190121	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB4A protein levels (SeqId = 16883-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB4A protein levels (SeqId = 16883-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-4A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000052	None	Gadd-DA_rab4a_protein_levels__seqid___16883-57__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GAD1 protein levels (SeqId = 11280-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GAD1 protein levels (SeqId = 11280-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutamate decarboxylase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000052	None	Gadd-DA_gad1_protein_levels__seqid___11280-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STMN2 protein levels (SeqId = 10900-272)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STMN2 protein levels (SeqId = 10900-272)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Stathmin-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000052	None	Gadd-DA_stmn2_protein_levels__seqid___10900-272__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDX39B protein levels (SeqId = 9742-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDX39B protein levels (SeqId = 9742-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Spliceosome RNA helicase DDX39B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000052	None	Gadd-DA_ddx39b_protein_levels__seqid___9742-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IRF6 protein levels (SeqId = 9999-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IRF6 protein levels (SeqId = 9999-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon regulatory factor 6	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000052	None	Gadd-DA_irf6_protein_levels__seqid___9999-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C1orf198 protein levels (SeqId = 8035-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C1orf198 protein levels (SeqId = 8035-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uncharacterized protein C1orf198	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000052	None	Gadd-DA_c1orf198_protein_levels__seqid___8035-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COLGALT1 protein levels (SeqId = 5638-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COLGALT1 protein levels (SeqId = 5638-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Procollagen galactosyltransferase 1	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.73	0.181	0.000052	None	Gadd-DA_colgalt1_protein_levels__seqid___5638-23__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.0396113	0.00978871	0.00005222545	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14567287	chr7:157129156	7	157129156	DNAJB6	Island	-0.0339294	0.00838813	0.00005260796	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0333668	0.00825197	0.00005293014	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ALKBH3 protein levels (SeqId = 18401-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALKBH3 protein levels (SeqId = 18401-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000053	None	Gadd-DA_alkbh3_protein_levels__seqid___18401-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MPP7 protein levels (SeqId = 12732-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MPP7 protein levels (SeqId = 12732-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAGUK p55 subfamily member 7	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.52	0.127	0.000053	None	Gadd-DA_mpp7_protein_levels__seqid___12732-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CAMK4 protein levels (SeqId = 18904-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAMK4 protein levels (SeqId = 18904-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium/calmodulin-dependent protein kinase type IV	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000053	None	Gadd-DA_camk4_protein_levels__seqid___18904-23__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.0335535	0.00830471	0.00005365712	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	0.0446308	0.0110474	0.00005373997	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	YEATS4 protein levels (SeqId = 17474-106)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YEATS4 protein levels (SeqId = 17474-106)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: YEATS domain-containing protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000054	None	Gadd-DA_yeats4_protein_levels__seqid___17474-106__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TDP1 protein levels (SeqId = 10073-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TDP1 protein levels (SeqId = 10073-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosyl-DNA phosphodiesterase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000054	None	Gadd-DA_tdp1_protein_levels__seqid___10073-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAEP protein levels (SeqId = 8867-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAEP protein levels (SeqId = 8867-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycodelin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000054	None	Gadd-DA_paep_protein_levels__seqid___8867-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSNK2A1 protein levels (SeqId = 3427-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSNK2A1 protein levels (SeqId = 3427-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Casein kinase II subunit alpha	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000054	None	Gadd-DA_csnk2a1_protein_levels__seqid___3427-63__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	0.0333097	0.00825199	0.00005451513	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0025	None	0.000055	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	NSF protein levels (SeqId = 13992-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NSF protein levels (SeqId = 13992-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vesicle-fusing ATPase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000055	None	Gadd-DA_nsf_protein_levels__seqid___13992-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KCNA10 protein levels (SeqId = 13042-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KCNA10 protein levels (SeqId = 13042-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Potassium voltage-gated channel subfamily A member 10	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.514	0.127	0.000055	None	Gadd-DA_kcna10_protein_levels__seqid___13042-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KCNAB2 protein levels (SeqId = 10015-119)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KCNAB2 protein levels (SeqId = 10015-119)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Voltage-gated potassium channel subunit beta-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000055	None	Gadd-DA_kcnab2_protein_levels__seqid___10015-119__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	YBX2 protein levels (SeqId = 6372-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YBX2 protein levels (SeqId = 6372-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Y-box-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000055	None	Gadd-DA_ybx2_protein_levels__seqid___6372-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPAST protein levels (SeqId = 8388-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPAST protein levels (SeqId = 8388-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Spastin	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.73	0.18	0.000055	None	Gadd-DA_spast_protein_levels__seqid___8388-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SAP18 protein levels (SeqId = 12830-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SAP18 protein levels (SeqId = 12830-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histone deacetylase complex subunit SAP18	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.62	0.154	0.000055	None	Gadd-DA_sap18_protein_levels__seqid___12830-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	-0.0332802	0.008252	0.00005535149	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0441213	0.0109416	0.0000554802	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.044844	0.0111232	0.00005568278	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03836195	chr7:157205668	7	157205668	DNAJB6	North shore	0.0031	None	0.000056	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	CASS4 protein levels (SeqId = 12855-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASS4 protein levels (SeqId = 12855-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cas scaffolding protein family member 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000056	None	Gadd-DA_cass4_protein_levels__seqid___12855-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	0.0394794	0.00979661	0.0000560803	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F3	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	53	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-	-	0.0000565	-	26500701_sex_kora_f3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.033226	0.00825201	0.00005691996	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	DSC1 protein levels (SeqId = 10882-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DSC1 protein levels (SeqId = 10882-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Desmocollin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000057	None	Gadd-DA_dsc1_protein_levels__seqid___10882-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RLN3 protein levels (SeqId = 6027-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RLN3 protein levels (SeqId = 6027-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Relaxin-3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000057	None	Gadd-DA_rln3_protein_levels__seqid___6027-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BDNF protein levels (SeqId = 2421-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BDNF protein levels (SeqId = 2421-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Brain-derived neurotrophic factor	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.726	0.18	0.000057	None	Gadd-DA_bdnf_protein_levels__seqid___2421-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	0.0366834	0.00911228	0.00005709013	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	0.0371774	0.00923654	0.00005725361	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26668151	chr7:157180005	7	157180005	DNAJB6	Open sea	0.0332032	0.00825202	0.0000575902	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	IGJ protein levels (SeqId = 15306-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IGJ protein levels (SeqId = 15306-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin J chain	774	1	Adults (18-65 years)	Both	European	cg06229455	chr7:157189721	7	157189721	DNAJB6	North shelf	-0.69	0.173	0.000058	None	Gadd-DA_igj_protein_levels__seqid___15306-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BST2 protein levels (SeqId = 8832-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BST2 protein levels (SeqId = 8832-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bone marrow stromal antigen 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000058	None	Gadd-DA_bst2_protein_levels__seqid___8832-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HTR2A protein levels (SeqId = 13556-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HTR2A protein levels (SeqId = 13556-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 5-hydroxytryptamine receptor 2A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000058	None	Gadd-DA_htr2a_protein_levels__seqid___13556-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DLG4 protein levels (SeqId = 8070-88)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DLG4 protein levels (SeqId = 8070-88)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Disks large homolog 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000059	None	Gadd-DA_dlg4_protein_levels__seqid___8070-88__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CPXM1 protein levels (SeqId = 6255-74)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CPXM1 protein levels (SeqId = 6255-74)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable carboxypeptidase X1	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.73	0.181	0.000059	None	Gadd-DA_cpxm1_protein_levels__seqid___6255-74__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	-0.0331444	0.00825204	0.00005936066	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0331297	0.00825204	0.00005980923	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12910268	chr7:157185351	7	157185351	DNAJB6	Open sea	-0.0331242	0.00825204	0.00005997906	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	RHOC protein levels (SeqId = 17764-108)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RHOC protein levels (SeqId = 17764-108)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho-related GTP-binding protein RhoC	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.512	0.127	0.00006	None	Gadd-DA_rhoc_protein_levels__seqid___17764-108__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB14 protein levels (SeqId = 8053-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB14 protein levels (SeqId = 8053-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 14	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.00006	None	Gadd-DA_dnajb14_protein_levels__seqid___8053-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BTNL8 protein levels (SeqId = 9026-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BTNL8 protein levels (SeqId = 9026-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Butyrophilin-like protein 8	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.00006	None	Gadd-DA_btnl8_protein_levels__seqid___9026-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CXADR protein levels (SeqId = 11204-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXADR protein levels (SeqId = 11204-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coxsackievirus and adenovirus receptor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.00006	None	Gadd-DA_cxadr_protein_levels__seqid___11204-80__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	-0.0366053	0.00912161	0.00006024181	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CBR1 protein levels (SeqId = 12381-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBR1 protein levels (SeqId = 12381-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carbonyl reductase [NADPH] 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000061	None	Gadd-DA_cbr1_protein_levels__seqid___12381-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CHST14 protein levels (SeqId = 7262-191)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHST14 protein levels (SeqId = 7262-191)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carbohydrate sulfotransferase 14	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000061	None	Gadd-DA_chst14_protein_levels__seqid___7262-191__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CD247 protein levels (SeqId = 15567-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD247 protein levels (SeqId = 15567-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: T-cell surface glycoprotein CD3 zeta chain	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000063	None	Gadd-DA_cd247_protein_levels__seqid___15567-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPRD1A protein levels (SeqId = 13515-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPRD1A protein levels (SeqId = 13515-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Regulation of nuclear pre-mRNA domain-containing protein 1A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000063	None	Gadd-DA_rprd1a_protein_levels__seqid___13515-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MMAB protein levels (SeqId = 17783-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MMAB protein levels (SeqId = 17783-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Corrinoid adenosyltransferase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000063	None	Gadd-DA_mmab_protein_levels__seqid___17783-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HINT1 protein levels (SeqId = 5900-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HINT1 protein levels (SeqId = 5900-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histidine triad nucleotide-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000063	None	Gadd-DA_hint1_protein_levels__seqid___5900-11__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0356085	0.00889788	0.00006314207	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12381188	chr7:157199595	7	157199595	DNAJB6	North shelf	-0.0330198	0.00825207	0.00006328007	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08010530	chr7:157200028	7	157200028	DNAJB6	North shelf	0.0333346	0.00833082	0.00006328759	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00004836	chr7:157155664	7	157155664	DNAJB6	Open sea	-0.0330123	0.00825207	0.00006352317	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0355854	0.0088979	0.00006384181	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Total cholesterol in very large VLDL	EFO_0004574	None	None	DNA methylation	Total cholesterol in very large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	646	1	Adults	Females	European	cg12577647	chr7:157178981	7	157178981	DNAJB6	Open sea	-13.6	3.4	0.000064	None	Battram-T_total_cholesterol_in_very_large_vldl
Gadd DA	Generation Scotland	35945220	31/07/2022	CPVL protein levels (SeqId = 8891-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CPVL protein levels (SeqId = 8891-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable serine carboxypeptidase CPVL	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000064	None	Gadd-DA_cpvl_protein_levels__seqid___8891-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TCF4 protein levels (SeqId = 19144-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TCF4 protein levels (SeqId = 19144-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription factor 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000064	None	Gadd-DA_tcf4_protein_levels__seqid___19144-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TCEA1 protein levels (SeqId = 18204-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TCEA1 protein levels (SeqId = 18204-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription elongation factor A protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000064	None	Gadd-DA_tcea1_protein_levels__seqid___18204-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GPN1 protein levels (SeqId = 16599-38)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GPN1 protein levels (SeqId = 16599-38)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GPN-loop GTPase 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000064	None	Gadd-DA_gpn1_protein_levels__seqid___16599-38__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NXF1 protein levels (SeqId = 12453-161)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NXF1 protein levels (SeqId = 12453-161)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear RNA export factor 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000064	None	Gadd-DA_nxf1_protein_levels__seqid___12453-161__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	REPIN1 protein levels (SeqId = 13554-78)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	REPIN1 protein levels (SeqId = 13554-78)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Replication initiator 1	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.62	0.154	0.000064	None	Gadd-DA_repin1_protein_levels__seqid___13554-78__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MYL5 protein levels (SeqId = 19286-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYL5 protein levels (SeqId = 19286-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Myosin light chain 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000065	None	Gadd-DA_myl5_protein_levels__seqid___19286-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRC1 protein levels (SeqId = 15310-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRC1 protein levels (SeqId = 15310-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein regulator of cytokinesis 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000065	None	Gadd-DA_prc1_protein_levels__seqid___15310-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB14 protein levels (SeqId = 8053-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB14 protein levels (SeqId = 8053-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 14	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.72	0.181	0.000065	None	Gadd-DA_dnajb14_protein_levels__seqid___8053-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0542887	0.0135907	0.00006513472	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26309551	chr7:157168713	7	157168713	DNAJB6	Open sea	-0.0329581	0.00825209	0.000065309	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Lunnon K	-	25129077	2014-08-17	Alzheimers disease Braak stage	EFO_0000249, EFO_0006801	Discovery in entorhinal cortex	Table S3	DNA methylation	Alzheimers disease Braak stage	Age, sex and technical covariates	Beta values	-	Illumina HumanMethylation450	Entorhinal cortex	-	104	1	-	Missing	None	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	-	-	0.0000655	-	25129077_alzheimers_disease_braak_stage_discovery_in_entorhinal_cortex
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.038362	0.00960717	0.00006554487	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.300477	0.0752556	0.00006557977	None	39706196_Hannah-M.-Smith_body_fat_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Rheumatoid Arthritis (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Rheumatoid Arthritis (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18055	1	Adults (18-65y)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.062	0.0155	0.000066	None	Robert-F-Hillary_Prevalent_Rheumatoid_Arthritis_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	SNAI2 protein levels (SeqId = 10014-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNAI2 protein levels (SeqId = 10014-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Zinc finger protein SNAI2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000066	None	Gadd-DA_snai2_protein_levels__seqid___10014-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	THPO protein levels (SeqId = 8059-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	THPO protein levels (SeqId = 8059-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thrombopoietin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000066	None	Gadd-DA_thpo_protein_levels__seqid___8059-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HDGFRP2 protein levels (SeqId = 4553-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDGFRP2 protein levels (SeqId = 4553-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatoma-derived growth factor-related protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000066	None	Gadd-DA_hdgfrp2_protein_levels__seqid___4553-65__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02271119	chr7:157198869	7	157198869	DNAJB6	North shelf	-0.0408307	0.0102339	0.00006646301	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05726556	chr7:157203124	7	157203124	DNAJB6	Island	0.0326948	0.00819563	0.00006659024	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	0.0329133	0.0082521	0.00006682193	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CEACAM3 protein levels (SeqId = 8999-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CEACAM3 protein levels (SeqId = 8999-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carcinoembryonic antigen-related cell adhesion molecule 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000067	None	Gadd-DA_ceacam3_protein_levels__seqid___8999-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NUDT9 protein levels (SeqId = 9482-110)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUDT9 protein levels (SeqId = 9482-110)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribose pyrophosphatase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000067	None	Gadd-DA_nudt9_protein_levels__seqid___9482-110__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAB2 protein levels (SeqId = 3399-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAB2 protein levels (SeqId = 3399-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Stabilin-2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000067	None	Gadd-DA_stab2_protein_levels__seqid___3399-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSH1 protein levels (SeqId = 13103-125)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSH1 protein levels (SeqId = 13103-125)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chorionic somatomammotropin hormone 2|Chorionic somatomammotropin hormone 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000067	None	Gadd-DA_csh1_protein_levels__seqid___13103-125__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANAPC10 protein levels (SeqId = 12345-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANAPC10 protein levels (SeqId = 12345-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Anaphase-promoting complex subunit 10	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.507	0.127	0.000067	None	Gadd-DA_anapc10_protein_levels__seqid___12345-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FUT8 protein levels (SeqId = 8244-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FUT8 protein levels (SeqId = 8244-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-(1,6)-fucosyltransferase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000067	None	Gadd-DA_fut8_protein_levels__seqid___8244-16__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg01766193	chr7:157202248	7	157202248	DNAJB6	North shore	-0.12847	0.0322	0.0000675	-	27105112_hiv_infection_neutrophils
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.0328888	0.0082521	0.00006766432	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02696201	chr7:157179773	7	157179773	DNAJB6	Open sea	-0.0336844	0.00845342	0.00006789072	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Lung Cancer	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Lung Cancer	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18364	1	Adults (18-65y)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.013	0.00325	0.000068	None	Robert-F-Hillary_Incident_Lung_Cancer_Basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13515783	chr7:157201622	7	157201622	DNAJB6	North shore	0.0033	None	0.000068	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	TIMM50 protein levels (SeqId = 7743-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TIMM50 protein levels (SeqId = 7743-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitochondrial import inner membrane translocase subunit TIM50	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000068	None	Gadd-DA_timm50_protein_levels__seqid___7743-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LMNB1 protein levels (SeqId = 3889-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LMNB1 protein levels (SeqId = 3889-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lamin-B1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000068	None	Gadd-DA_lmnb1_protein_levels__seqid___3889-64__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NDUFA5 protein levels (SeqId = 19200-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NDUFA5 protein levels (SeqId = 19200-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.507	0.127	0.000068	None	Gadd-DA_ndufa5_protein_levels__seqid___19200-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SYT11 protein levels (SeqId = 7089-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SYT11 protein levels (SeqId = 7089-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Synaptotagmin-11	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000068	None	Gadd-DA_syt11_protein_levels__seqid___7089-42__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.028	0.00713	0.000068	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0328654	0.00825211	0.00006847544	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	0.0328536	0.00825211	0.00006888759	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PARK2 protein levels (SeqId = 13013-41)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PARK2 protein levels (SeqId = 13013-41)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase parkin	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000069	None	Gadd-DA_park2_protein_levels__seqid___13013-41__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ULBP1 protein levels (SeqId = 3081-70)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ULBP1 protein levels (SeqId = 3081-70)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UL16-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000069	None	Gadd-DA_ulbp1_protein_levels__seqid___3081-70__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDE1A protein levels (SeqId = 5253-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDE1A protein levels (SeqId = 5253-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000069	None	Gadd-DA_pde1a_protein_levels__seqid___5253-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDIT3 protein levels (SeqId = 19119-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDIT3 protein levels (SeqId = 19119-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA damage-inducible transcript 3 protein	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000069	None	Gadd-DA_ddit3_protein_levels__seqid___19119-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PARK2 protein levels (SeqId = 13013-41)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PARK2 protein levels (SeqId = 13013-41)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase parkin	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.61	0.154	0.000069	None	Gadd-DA_park2_protein_levels__seqid___13013-41__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	-0.0328448	0.00825212	0.00006919979	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0328423	0.00825212	0.00006928676	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.105574	0.0265296	0.00006934591	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0328402	0.00825212	0.00006936073	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	0.0361757	0.0090904	0.00006937694	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.0422013	0.0106085	0.00006981002	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02994253	chr7:157209799	7	157209799	DNAJB6	North shore	0.0079	0.002	0.00007	None	33450751_Mulder-RH_sex_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK8 protein levels (SeqId = 3825-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK8 protein levels (SeqId = 3825-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 8	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.00007	None	Gadd-DA_mapk8_protein_levels__seqid___3825-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL1RL2 protein levels (SeqId = 2994-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL1RL2 protein levels (SeqId = 2994-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-1 receptor-like 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.00007	None	Gadd-DA_il1rl2_protein_levels__seqid___2994-71__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0328153	0.00825212	0.00007024547	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0328138	0.00825213	0.00007030007	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0550486	0.0138475	0.00007061771	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	ECEL1 protein levels (SeqId = 7076-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ECEL1 protein levels (SeqId = 7076-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endothelin-converting enzyme-like 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000071	None	Gadd-DA_ecel1_protein_levels__seqid___7076-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARL8B protein levels (SeqId = 8569-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARL8B protein levels (SeqId = 8569-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor-like protein 8B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.506	0.127	0.000071	None	Gadd-DA_arl8b_protein_levels__seqid___8569-147__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DTX3L protein levels (SeqId = 11643-73)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DTX3L protein levels (SeqId = 11643-73)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase DTX3L	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000071	None	Gadd-DA_dtx3l_protein_levels__seqid___11643-73__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MADCAM1 protein levels (SeqId = 11258-41)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MADCAM1 protein levels (SeqId = 11258-41)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mucosal addressin cell adhesion molecule 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.506	0.127	0.000071	None	Gadd-DA_madcam1_protein_levels__seqid___11258-41__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0439983	0.0110797	0.00007189071	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	LZIC protein levels (SeqId = 19338-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LZIC protein levels (SeqId = 19338-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein LZIC	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.51	0.127	0.000072	None	Gadd-DA_lzic_protein_levels__seqid___19338-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TTL protein levels (SeqId = 13973-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TTL protein levels (SeqId = 13973-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tubulin--tyrosine ligase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.504	0.127	0.000072	None	Gadd-DA_ttl_protein_levels__seqid___13973-62__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0327662	0.00825214	0.00007202447	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10161638	chr7:157191746	7	157191746	DNAJB6	North shore	0.0363139	0.0091466	0.00007215303	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0367128	0.00925204	0.00007280162	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.032745	0.00825214	0.00007280631	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	IL17RD protein levels (SeqId = 3376-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL17RD protein levels (SeqId = 3376-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-17 receptor D	774	1	Adults (18-65 years)	Both	European	cg27525636	chr7:157171342	7	157171342	DNAJB6	Open sea	-0.84	0.213	0.000073	None	Gadd-DA_il17rd_protein_levels__seqid___3376-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	0.0327346	0.00825215	0.00007319232	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.035805	0.00902642	0.00007322346	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0327337	0.00825215	0.00007322536	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0327287	0.00825215	0.00007341023	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0327235	0.00825215	0.00007360461	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Liu J	Rotterdam Study III-1, Rotterdam Study II-3 and Rotterdam Study III-2, Netherlands Twin Register, UK adult Twin registry	31197173	2013-06-19	fasting glucose	EFO_0004465	Base plus BMI	Supplementary Data 1	DNA methylation	fasting glucose	Age, sex, smoking, cell composition (reference based), batch effects, body mass index	Beta Values	mmol/L	Illumina HumanMethylation450	whole blood	None	4808	4	Adults	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-1.15	0.29	0.000074	4807	31197173_Liu-J_fasting_glucose_base_plus_bmi
Gadd DA	Generation Scotland	35945220	31/07/2022	MRPL21 protein levels (SeqId = 8942-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MRPL21 protein levels (SeqId = 8942-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 39S ribosomal protein L21, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.72	0.181	0.000074	None	Gadd-DA_mrpl21_protein_levels__seqid___8942-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0356187	0.00898588	0.00007409968	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	-0.0326989	0.00825216	0.00007453211	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.0326903	0.00825216	0.00007485478	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0326893	0.00825216	0.00007489401	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Battram T	ARIES	None	2020-08-20	Phospholipids to total lipids ratio in large VLDL	EFO_0004639	None	None	DNA methylation	Phospholipids to total lipids ratio in large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	627	1	Adults	Females	European	cg17186355	chr7:157206798	7	157206798	DNAJB6	North shore	-0.062	0.0154	0.000075	None	Battram-T_phospholipids_to_total_lipids_ratio_in_large_vldl
Gadd DA	Generation Scotland	35945220	31/07/2022	MPL protein levels (SeqId = 3473-78)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MPL protein levels (SeqId = 3473-78)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thrombopoietin receptor	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000075	None	Gadd-DA_mpl_protein_levels__seqid___3473-78__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AIFM1 protein levels (SeqId = 9522-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AIFM1 protein levels (SeqId = 9522-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Apoptosis-inducing factor 1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000075	None	Gadd-DA_aifm1_protein_levels__seqid___9522-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TTC17 protein levels (SeqId = 8800-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TTC17 protein levels (SeqId = 8800-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tetratricopeptide repeat protein 17	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000075	None	Gadd-DA_ttc17_protein_levels__seqid___8800-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLEC4G protein levels (SeqId = 10781-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLEC4G protein levels (SeqId = 10781-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-type lectin domain family 4 member G	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.72	0.181	0.000075	None	Gadd-DA_clec4g_protein_levels__seqid___10781-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0353481	0.00892461	0.00007507006	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26309551	chr7:157168713	7	157168713	DNAJB6	Open sea	-0.0326709	0.00825216	0.0000755967	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SLC14A1 protein levels (SeqId = 13430-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SLC14A1 protein levels (SeqId = 13430-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Urea transporter 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000076	None	Gadd-DA_slc14a1_protein_levels__seqid___13430-50__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0326527	0.00825217	0.00007629908	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	0.953875	0.2411	0.0000763	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0326499	0.00825217	0.00007640758	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	0.0326463	0.00825217	0.00007654615	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	-0.0352691	0.00891635	0.0000767171	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05726556	chr7:157203124	7	157203124	DNAJB6	Island	0.0041	None	0.000077	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	0.0326332	0.00825217	0.0000770545	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg19118904	chr7:157179789	7	157179789	DNAJB6	Open sea	-0.285169	0.0721	0.0000772	None	27105112_hiv_infection_cd4_tcells
Battram T	ARIES	None	2020-08-20	Cholesterol esters in chylomicrons and extremely large VLDL	EFO_0008589	None	None	DNA methylation	Cholesterol esters in chylomicrons and extremely large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	651	1	Adults	Females	European	cg12577647	chr7:157178981	7	157178981	DNAJB6	Open sea	-71	18	0.000078	None	Battram-T_cholesterol_esters_in_chylomicrons_and_extremely_large_vldl
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18327321	chr7:157193101	7	157193101	DNAJB6	Island	0.00764	0.00189	0.000078	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF8 protein levels (SeqId = 19570-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF8 protein levels (SeqId = 19570-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 8	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000078	None	Gadd-DA_fgf8_protein_levels__seqid___19570-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CAPN3 protein levels (SeqId = 12385-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAPN3 protein levels (SeqId = 12385-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calpain-3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000078	None	Gadd-DA_capn3_protein_levels__seqid___12385-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CARHSP1 protein levels (SeqId = 12808-103)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CARHSP1 protein levels (SeqId = 12808-103)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium-regulated heat-stable protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000078	None	Gadd-DA_carhsp1_protein_levels__seqid___12808-103__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CUL1 protein levels (SeqId = 17797-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CUL1 protein levels (SeqId = 17797-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cullin-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000078	None	Gadd-DA_cul1_protein_levels__seqid___17797-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.036558	0.0092541	0.00007836568	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	RELT protein levels (SeqId = 14112-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RELT protein levels (SeqId = 14112-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor receptor superfamily member 19L	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000079	None	Gadd-DA_relt_protein_levels__seqid___14112-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BDNF protein levels (SeqId = 14047-78)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BDNF protein levels (SeqId = 14047-78)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Brain-derived neurotrophic factor	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.71	0.181	0.000079	None	Gadd-DA_bdnf_protein_levels__seqid___14047-78__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EFNB3 protein levels (SeqId = 7785-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EFNB3 protein levels (SeqId = 7785-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ephrin-B3	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.607	0.154	0.000079	None	Gadd-DA_efnb3_protein_levels__seqid___7785-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.032583	0.00825219	0.00007903818	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NFKB1 protein levels (SeqId = 9869-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NFKB1 protein levels (SeqId = 9869-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear factor NF-kappa-B p105 subunit	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.00008	None	Gadd-DA_nfkb1_protein_levels__seqid___9869-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CNDP2 protein levels (SeqId = 3192-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CNDP2 protein levels (SeqId = 3192-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytosolic non-specific dipeptidase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.00008	None	Gadd-DA_cndp2_protein_levels__seqid___3192-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACOT8 protein levels (SeqId = 17400-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACOT8 protein levels (SeqId = 17400-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-coenzyme A thioesterase 8	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.502	0.127	0.00008	None	Gadd-DA_acot8_protein_levels__seqid___17400-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRSS27 protein levels (SeqId = 15535-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRSS27 protein levels (SeqId = 15535-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine protease 27	774	1	Adults (18-65 years)	Both	European	cg00004836	chr7:157155664	7	157155664	DNAJB6	Open sea	-0.9	0.229	0.00008	None	Gadd-DA_prss27_protein_levels__seqid___15535-3__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg23564939	chr7:157209061	7	157209061	DNAJB6	South shore	-0.163966	0.0415906	0.00008098054	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	GLRX2 protein levels (SeqId = 12486-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GLRX2 protein levels (SeqId = 12486-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutaredoxin-2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000081	None	Gadd-DA_glrx2_protein_levels__seqid___12486-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FNDC4 protein levels (SeqId = 13451-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FNDC4 protein levels (SeqId = 13451-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibronectin type III domain-containing protein 4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000081	None	Gadd-DA_fndc4_protein_levels__seqid___13451-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CAPNS1 protein levels (SeqId = 18299-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAPNS1 protein levels (SeqId = 18299-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calpain small subunit 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000081	None	Gadd-DA_capns1_protein_levels__seqid___18299-13__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	0.0395863	0.0100444	0.00008147992	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CNEP1R1 protein levels (SeqId = 13532-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CNEP1R1 protein levels (SeqId = 13532-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear envelope phosphatase-regulatory subunit 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000082	None	Gadd-DA_cnep1r1_protein_levels__seqid___13532-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CYTH4 protein levels (SeqId = 12746-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CYTH4 protein levels (SeqId = 12746-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytohesin-4	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000082	None	Gadd-DA_cyth4_protein_levels__seqid___12746-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	0.0389348	0.00988781	0.00008266302	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	GPR135 protein levels (SeqId = 11465-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GPR135 protein levels (SeqId = 11465-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: G-protein coupled receptor 135	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000083	None	Gadd-DA_gpr135_protein_levels__seqid___11465-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAN protein levels (SeqId = 4282-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAN protein levels (SeqId = 4282-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GTP-binding nuclear protein Ran	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000083	None	Gadd-DA_ran_protein_levels__seqid___4282-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04655959	chr7:157185087	7	157185087	DNAJB6	Open sea	0.0324862	0.00825221	0.0000830036	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02994253	chr7:157209799	7	157209799	DNAJB6	North shore	0.0323096	0.00820893	0.00008326249	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	0.03248	0.00825222	0.00008326265	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	0.0324793	0.00825222	0.00008329112	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27139827	chr7:157139514	7	157139514	DNAJB6	Open sea	-0.0389738	0.0099028	0.00008336089	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	ARF1 protein levels (SeqId = 19239-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARF1 protein levels (SeqId = 19239-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000084	None	Gadd-DA_arf1_protein_levels__seqid___19239-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CENPW protein levels (SeqId = 8864-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CENPW protein levels (SeqId = 8864-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Centromere protein W	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000084	None	Gadd-DA_cenpw_protein_levels__seqid___8864-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PTP4A3 protein levels (SeqId = 19231-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTP4A3 protein levels (SeqId = 19231-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein tyrosine phosphatase type IVA 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000084	None	Gadd-DA_ptp4a3_protein_levels__seqid___19231-22__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00114346	chr7:157207886	7	157207886	DNAJB6	North shore	0.0324539	0.00825222	0.00008436877	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	-0.0324407	0.00825223	0.00008492999	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17529436	chr7:157201728	7	157201728	DNAJB6	North shore	0.0023	None	0.000085	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	NDE1 protein levels (SeqId = 9765-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NDE1 protein levels (SeqId = 9765-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear distribution protein nudE homolog 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000085	None	Gadd-DA_nde1_protein_levels__seqid___9765-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RNF41 protein levels (SeqId = 13411-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RNF41 protein levels (SeqId = 13411-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase NRDP1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.501	0.127	0.000085	None	Gadd-DA_rnf41_protein_levels__seqid___13411-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TP53I3 protein levels (SeqId = 17748-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TP53I3 protein levels (SeqId = 17748-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Quinone oxidoreductase PIG3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000085	None	Gadd-DA_tp53i3_protein_levels__seqid___17748-21__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08620789	chr7:157129638	7	157129638	DNAJB6	Island	0.00044	None	0.000087	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	IFIT3 protein levels (SeqId = 13642-90)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFIT3 protein levels (SeqId = 13642-90)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon-induced protein with tetratricopeptide repeats 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000087	None	Gadd-DA_ifit3_protein_levels__seqid___13642-90__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CEL protein levels (SeqId = 9796-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CEL protein levels (SeqId = 9796-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bile salt-activated lipase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000087	None	Gadd-DA_cel_protein_levels__seqid___9796-4__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg12381188	chr7:157199595	7	157199595	DNAJB6	North shelf	0.182813	0.0465754	0.00008702938	None	39706196_Hannah-M.-Smith_body_fat_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	0.185191	0.0472131	0.00008797284	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12381188	chr7:157199595	7	157199595	DNAJB6	North shelf	0.0025	None	0.000088	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	SLC26A7 protein levels (SeqId = 13979-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SLC26A7 protein levels (SeqId = 13979-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Anion exchange transporter	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000088	None	Gadd-DA_slc26a7_protein_levels__seqid___13979-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAR protein levels (SeqId = 10085-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAR protein levels (SeqId = 10085-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Steroidogenic acute regulatory protein, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg27565794	chr7:157207336	7	157207336	DNAJB6	Island	0.71	0.181	0.000088	None	Gadd-DA_star_protein_levels__seqid___10085-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PIWIL1 protein levels (SeqId = 12793-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIWIL1 protein levels (SeqId = 12793-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Piwi-like protein 1	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.6	0.154	0.000088	None	Gadd-DA_piwil1_protein_levels__seqid___12793-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17950348	chr7:157183466	7	157183466	DNAJB6	Open sea	0.0840083	0.0214165	0.00008800264	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0379017	0.00966588	0.00008851698	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	LOXL3 protein levels (SeqId = 15427-35)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LOXL3 protein levels (SeqId = 15427-35)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lysyl oxidase homolog 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000089	None	Gadd-DA_loxl3_protein_levels__seqid___15427-35__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAR protein levels (SeqId = 10085-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAR protein levels (SeqId = 10085-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Steroidogenic acute regulatory protein, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000089	None	Gadd-DA_star_protein_levels__seqid___10085-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	THOC1 protein levels (SeqId = 9875-107)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	THOC1 protein levels (SeqId = 9875-107)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: THO complex subunit 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000089	None	Gadd-DA_thoc1_protein_levels__seqid___9875-107__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RUFY1 protein levels (SeqId = 11425-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RUFY1 protein levels (SeqId = 11425-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RUN and FYVE domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000089	None	Gadd-DA_rufy1_protein_levels__seqid___11425-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LTB4R protein levels (SeqId = 13477-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LTB4R protein levels (SeqId = 13477-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leukotriene B4 receptor 1	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.599	0.153	0.000089	None	Gadd-DA_ltb4r_protein_levels__seqid___13477-65__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06858263	chr7:157148509	7	157148509	DNAJB6	Open sea	-0.032338	0.00825225	0.00008943819	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GMEB2 protein levels (SeqId = 12804-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GMEB2 protein levels (SeqId = 12804-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glucocorticoid modulatory element-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.00009	None	Gadd-DA_gmeb2_protein_levels__seqid___12804-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DGCR14 protein levels (SeqId = 11356-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DGCR14 protein levels (SeqId = 11356-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Splicing factor ESS-2 homolog	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.00009	None	Gadd-DA_dgcr14_protein_levels__seqid___11356-19__somascan_protein_measurement
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg11695266	chr7:157129166	7	157129166	DNAJB6	Island	0.2270664	0.0580077	0.00009062	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Gadd DA	Generation Scotland	35945220	31/07/2022	NME1 protein levels (SeqId = 5909-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NME1 protein levels (SeqId = 5909-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nucleoside diphosphate kinase A	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000091	None	Gadd-DA_nme1_protein_levels__seqid___5909-51__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0432516	0.011053	0.00009152587	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09316472	chr7:157131900	7	157131900	DNAJB6	South shore	0.0322896	0.00825227	0.00009163786	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PDGFRA protein levels (SeqId = 10366-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDGFRA protein levels (SeqId = 10366-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet-derived growth factor receptor alpha	774	1	Adults (18-65 years)	Both	European	cg23170771	chr7:157129064	7	157129064	DNAJB6	North shore	0.54	0.138	0.000092	None	Gadd-DA_pdgfra_protein_levels__seqid___10366-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MARK3 protein levels (SeqId = 9747-48)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MARK3 protein levels (SeqId = 9747-48)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAP/microtubule affinity-regulating kinase 3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000092	None	Gadd-DA_mark3_protein_levels__seqid___9747-48__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCK protein levels (SeqId = 6918-183)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCK protein levels (SeqId = 6918-183)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cholecystokinin	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.603	0.154	0.000092	None	Gadd-DA_cck_protein_levels__seqid___6918-183__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.032263	0.00825227	0.00009286827	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10955910	chr7:157207907	7	157207907	DNAJB6	South shore	-0.0385561	0.00986227	0.00009292075	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CD14 protein levels (SeqId = 16914-104)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD14 protein levels (SeqId = 16914-104)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Monocyte differentiation antigen CD14	774	1	Adults (18-65 years)	Both	European	cg05077108	chr7:157200263	7	157200263	DNAJB6	North shelf	0.77	0.196	0.000094	None	Gadd-DA_cd14_protein_levels__seqid___16914-104__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LIN7B protein levels (SeqId = 15612-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LIN7B protein levels (SeqId = 15612-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein lin-7 homolog B	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000094	None	Gadd-DA_lin7b_protein_levels__seqid___15612-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPFIA1 protein levels (SeqId = 13975-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPFIA1 protein levels (SeqId = 13975-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Liprin-alpha-1	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.495	0.127	0.000094	None	Gadd-DA_ppfia1_protein_levels__seqid___13975-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HAGH protein levels (SeqId = 19267-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HAGH protein levels (SeqId = 19267-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hydroxyacylglutathione hydrolase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000094	None	Gadd-DA_hagh_protein_levels__seqid___19267-14__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14213430	chr7:157190333	7	157190333	DNAJB6	North shelf	0.0391916	0.0100364	0.0000946688	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	PDCD1LG2 protein levels (SeqId = 3004-67)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDCD1LG2 protein levels (SeqId = 3004-67)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Programmed cell death 1 ligand 2	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000095	None	Gadd-DA_pdcd1lg2_protein_levels__seqid___3004-67__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25507226	chr7:157190734	7	157190734	DNAJB6	North shelf	0.0409033	0.0104811	0.00009559414	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	UNC5C protein levels (SeqId = 5139-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UNC5C protein levels (SeqId = 5139-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Netrin receptor UNC5C	774	1	Adults (18-65 years)	Both	European	cg05077108	chr7:157200263	7	157200263	DNAJB6	North shelf	0.76	0.196	0.000096	None	Gadd-DA_unc5c_protein_levels__seqid___5139-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TXNRD1 protein levels (SeqId = 13967-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXNRD1 protein levels (SeqId = 13967-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin reductase 1, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000096	None	Gadd-DA_txnrd1_protein_levels__seqid___13967-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ENO2 protein levels (SeqId = 10339-48)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ENO2 protein levels (SeqId = 10339-48)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-enolase	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000096	None	Gadd-DA_eno2_protein_levels__seqid___10339-48__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SLC26A5 protein levels (SeqId = 9127-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SLC26A5 protein levels (SeqId = 9127-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prestin	774	1	Adults (18-65 years)	Both	European	cg07093547	chr7:157180126	7	157180126	DNAJB6	Open sea	-0.6	0.153	0.000096	None	Gadd-DA_slc26a5_protein_levels__seqid___9127-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.0321775	0.0082523	0.00009693296	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS3 protein levels (SeqId = 5026-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS3 protein levels (SeqId = 5026-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 40S ribosomal protein S3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000097	None	Gadd-DA_rps3_protein_levels__seqid___5026-66__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS3A protein levels (SeqId = 5484-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS3A protein levels (SeqId = 5484-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 40S ribosomal protein S3a	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000097	None	Gadd-DA_rps3a_protein_levels__seqid___5484-63__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12128624	chr7:157170682	7	157170682	DNAJB6	Open sea	0.0321755	0.0082523	0.00009703207	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18362281	chr7:157204364	7	157204364	DNAJB6	Island	-0.032175	0.0082523	0.0000970555	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0353884	0.00907932	0.00009754578	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	IFI16 protein levels (SeqId = 12893-159)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFI16 protein levels (SeqId = 12893-159)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-interferon-inducible protein 16	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.49	0.127	0.000098	None	Gadd-DA_ifi16_protein_levels__seqid___12893-159__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDK protein levels (SeqId = 2911-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDK protein levels (SeqId = 2911-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Midkine	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000098	None	Gadd-DA_mdk_protein_levels__seqid___2911-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CTRC protein levels (SeqId = 5626-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CTRC protein levels (SeqId = 5626-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chymotrypsin-C	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000098	None	Gadd-DA_ctrc_protein_levels__seqid___5626-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CD74 protein levels (SeqId = 8748-45)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD74 protein levels (SeqId = 8748-45)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: HLA class II histocompatibility antigen gamma chain	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000098	None	Gadd-DA_cd74_protein_levels__seqid___8748-45__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07993586	chr7:157204960	7	157204960	DNAJB6	North shore	-0.0431281	0.0110698	0.00009822216	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14567287	chr7:157129156	7	157129156	DNAJB6	Island	-0.0326412	0.00838139	0.00009884442	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18245230	chr7:157204586	7	157204586	DNAJB6	Island	-0.0426295	0.0109467	0.00009892782	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Ribs bone mineral content	EFO_0007621	None	None	DNA methylation	Ribs bone mineral content	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	g	Illumina HumanMethylation450	Whole blood	DXA scan measurement	705	1	Adults	Females	European	cg08583888	chr7:157174475	7	157174475	DNAJB6	Open sea	-0.00107	0.00027	0.000099	None	Battram-T_ribs_bone_mineral_content
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13456653	chr7:157130065	7	157130065	DNAJB6	Island	0.0011	None	0.000099	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	LAMTOR3 protein levels (SeqId = 12490-92)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LAMTOR3 protein levels (SeqId = 12490-92)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ragulator complex protein LAMTOR3	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000099	None	Gadd-DA_lamtor3_protein_levels__seqid___12490-92__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GFER protein levels (SeqId = 15398-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GFER protein levels (SeqId = 15398-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: FAD-linked sulfhydryl oxidase ALR	774	1	Adults (18-65 years)	Both	European	cg25707994	chr7:157129685	7	157129685	DNAJB6	Island	-0.5	0.127	0.000099	None	Gadd-DA_gfer_protein_levels__seqid___15398-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05683808	chr7:157133186	7	157133186	DNAJB6	South shelf	0.033372	0.00857212	0.00009941372	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23208891	chr7:157183026	7	157183026	DNAJB6	Open sea	-0.0321256	0.00825231	0.00009948183	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03996020	chr7:157180124	7	157180124	DNAJB6	Open sea	-0.032124	0.00825231	0.0000995612	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04063230	chr7:157179830	7	157179830	DNAJB6	Open sea	-0.032121	0.00825231	0.00009971205	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1