author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01799681	chr6:11043368	6	11043368	ELOVL2	North shore	0.002	0.00023	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08683088	chr6:11007465	6	11007465	ELOVL2	Open sea	-0.0033	0.00026	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16323298	chr6:11044974	6	11044974	ELOVL2	Island	0.0023	0.00013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.013	0.00018	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.017	0.0012	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	-0.0027	0.00022	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20462795	chr6:10981184	6	10981184	ELOVL2	Open sea	-0.0039	0.00028	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0063	0.00012	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0078	0.00084	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21649660	chr6:10995125	6	10995125	ELOVL2	Open sea	-0.0015	0.00015	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0026	0.000053	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0012	None	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Reynolds LM	-	25404168	2014-11-18	Age	EFO_0000246	Monocytes	Additional file 1	DNA methylation	Age	Sex, ethnicity and technical covariates	M values	years	Illumina HumanMethylation450	Monocytes	-	1264	1	60	Both	European,African,Admixed	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-	-	1.28e-145	-	25404168_age_monocytes
Reynolds LM	-	25404168	2014-11-18	Age	EFO_0000246	Monocytes	Additional file 1	DNA methylation	Age	Sex, ethnicity and technical covariates	M values	years	Illumina HumanMethylation450	Monocytes	-	1264	1	60	Both	European,African,Admixed	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-	-	2.64e-124	-	25404168_age_monocytes
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-	-	4.73e-118	-	28056824_age_4_vs_age_0
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0034	0.00012	6.4e-117	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-	-	6.68e-115	-	28056824_age_4_vs_age_0
Reynolds LM	-	25404168	2014-11-18	Age	EFO_0000246	Monocytes	Additional file 1	DNA methylation	Age	Sex, ethnicity and technical covariates	M values	years	Illumina HumanMethylation450	Monocytes	-	1264	1	60	Both	European,African,Admixed	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-	-	1.13e-84	-	25404168_age_monocytes
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01799681	chr6:11043368	6	11043368	ELOVL2	North shore	-0.22269	0.00645	1.6999999999999999e-84	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0035	None	1.8e-72	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
McCartney DL	Generation Scotland: Scottish Family Health Study	31892350	2019-12-31	Age	EFO_0000246	Replication using MOMENT (mixed linear model-based method)	Table 1	DNA methylation	Age	Sex, batch effects, smoking, cell composition (reference free)	Beta Values	years	Illumina HumanMethylationEPIC	Whole Blood	None	4450	2	Adults	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	4.8	0.27	4e-71	None	31892350_McCartney-DL_age_replication_using_moment__mixed_linear_model-based_method_
Tajuddin SM	HANDLS	31426852	2019-08-19	Age	EFO_0001799	In African American individuals	Table 2, Table S1	DNA methylation	Age	Sex, ancestry (other), socioeconomic position, cell composition (reference based)	Beta Values	years	Illumina HumanMethylationEPIC	Whole Blood	Not all sites reported	237	1	Adults	Both	African	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.031	0.0018	1.7999999999999998e-70	None	31426852_Tajuddin-SM_age_in_african_american_individuals
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	1.02267866	0.0596	6.380000000000001e-66	-	25888029_ageing
Tajuddin SM	HANDLS	31426852	2019-08-19	Age	EFO_0001799	In white individuals	Table 2, Table S1	DNA methylation	Age	Sex, ancestry (other), socioeconomic position, cell composition (reference based)	Beta Values	years	Illumina HumanMethylationEPIC	Whole Blood	Not all sites reported	233	1	Adults	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.028	0.0017	3e-63	None	31426852_Tajuddin-SM_age_in_white_individuals
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0024	0.00013	1.7000000000000002e-58	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Florath I	-	24163245	2014-03-01	Age	EFO_0000246	-	Table 2	DNA methylation	Age	Sex, smoking behaviour, diabetes mellitus, cardiovascular disease, stroke, cancer and technical covariates	Beta values	Years	Illumina HumanMethylation450	Whole blood	-	498	1	62	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.048095	0.003	2.05e-58	-	24163245_age
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0013	0.00008	4.2e-53	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-	-	1.86e-44	-	28056824_age_4_vs_age_0
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.94752431	0.071	1.31e-40	-	25888029_ageing
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-	-	7.99e-39	-	23526956_clear_cell_renal_carcinoma
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-	-	3.0600000000000004e-36	-	23526956_clear_cell_renal_carcinoma
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-4.22268	0.19908	3.86e-36	-	25282492_fetal_vs_adult_liver
McCartney DL	Generation Scotland: Scottish Family Health Study	31892350	2019-12-31	Age	EFO_0000246	Discovery using MOMENT (mixed linear model-based method)	Table 1	DNA methylation	Age	Sex, batch effects, smoking, cell composition (reference free)	Beta Values	years	Illumina HumanMethylationEPIC	Whole Blood	None	2586	2	Adults	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	5	0.4	4e-36	None	31892350_McCartney-DL_age_discovery_using_moment__mixed_linear_model-based_method_
Florath I	-	24163245	2014-03-01	Age	EFO_0000246	-	Table 2	DNA methylation	Age	Sex, smoking behaviour, diabetes mellitus, cardiovascular disease, stroke, cancer and technical covariates	Beta values	Years	Illumina HumanMethylation450	Whole blood	-	498	1	62	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.047849	0.0039	5.34e-35	-	24163245_age
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	-0.06076	0.00407	5.3000000000000005e-34	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Li S	-	28811542	2017-08-15	Age	EFO_0000246	-	Table S1	DNA methylation	Age	Cell counts	M values	years	Illumina HumanMethylation450	Whole blood	-	1366	2	73	Missing	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.028	0.00231717	6.44e-34	-	28811542_age
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg16323298	chr6:11044974	6	11044974	ELOVL2	Island	-2.04282	0.10382	8.7e-34	-	25282492_fetal_vs_adult_liver
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	-	-	1.05e-33	-	23526956_clear_cell_renal_carcinoma
Reynolds LM	-	25404168	2014-11-18	Age	EFO_0000246	T cells	Additional file 1	DNA methylation	Age	Sex, ethnicity and technical covariates	M values	Years	Illumina HumanMethylation450	T cells	-	227	1	-	Missing	None	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-	-	1.98e-33	-	25404168_age_t_cells
Florath I	-	24163245	2014-03-01	Age	EFO_0000246	-	Table 2	DNA methylation	Age	Sex, smoking behaviour, diabetes mellitus, cardiovascular disease, stroke, cancer and technical covariates	Beta values	Years	Illumina HumanMethylation450	Whole blood	-	498	1	62	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.022746	0.0019	2.8000000000000002e-33	-	24163245_age
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-2.49716	0.13127	9.510000000000001e-33	-	25282492_fetal_vs_adult_liver
Li S	-	28811542	2017-08-15	Age	EFO_0000246	-	Table S1	DNA methylation	Age	Cell counts	M values	years	Illumina HumanMethylation450	Whole blood	-	1366	2	73	Missing	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.014	0.00118352	1.38e-32	-	28811542_age
Tajuddin SM	HANDLS	31426852	2019-08-19	Age	EFO_0001799	In African American individuals	Table 2, Table S1	DNA methylation	Age	Sex, ancestry (other), socioeconomic position, cell composition (reference based)	Beta Values	years	Illumina HumanMethylationEPIC	Whole Blood	Not all sites reported	237	1	Adults	Both	African	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.014	0.0012	2.3e-31	None	31426852_Tajuddin-SM_age_in_african_american_individuals
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0942278	0.00821984	2.7089149999999998e-30	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-3.42381	0.20014	1.42e-29	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	0.0909788	0.00822233	2.4052900000000003e-28	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Tajuddin SM	HANDLS	31426852	2019-08-19	Age	EFO_0001799	In white individuals	Table 2, Table S1	DNA methylation	Age	Sex, ancestry (other), socioeconomic position, cell composition (reference based)	Beta Values	years	Illumina HumanMethylationEPIC	Whole Blood	Not all sites reported	233	1	Adults	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.015	0.0014	2.6000000000000004e-28	None	31426852_Tajuddin-SM_age_in_white_individuals
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21649660	chr6:10995125	6	10995125	ELOVL2	Open sea	0.03729	0.00286	3e-28	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23642061	chr6:11043631	6	11043631	ELOVL2	North shore	0.00068	None	5.4e-26	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Reynolds LM	-	25404168	2014-11-18	Age	EFO_0000246	T cells	Additional file 1	DNA methylation	Age	Sex, ethnicity and technical covariates	M values	Years	Illumina HumanMethylation450	T cells	-	227	1	-	Missing	None	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-	-	7.23e-25	-	25404168_age_t_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0878492	0.00875935	1.351482e-23	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.107205	0.0107856	3.3118630000000005e-23	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	0.0816151	0.00822903	4.1125300000000004e-23	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0809475	0.00822948	9.238629000000001e-23	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.0977294	0.00999113	1.582889e-22	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01799681	chr6:11043368	6	11043368	ELOVL2	North shore	0.0023	None	3.4000000000000003e-22	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Reynolds LM	-	25404168	2014-11-18	Age	EFO_0000246	T cells	Additional file 1	DNA methylation	Age	Sex, ethnicity and technical covariates	M values	Years	Illumina HumanMethylation450	T cells	-	227	1	-	Missing	None	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-	-	1.7e-21	-	25404168_age_t_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.102328	0.0109043	7.255033e-21	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.0795443	0.00853084	1.273642e-20	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	0.0019	None	1.6e-20	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0779892	0.00847378	3.9216069999999996e-20	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Tajuddin SM	HANDLS	31426852	2019-08-19	Age	EFO_0001799	In white individuals	Table 2, Table S1	DNA methylation	Age	Sex, ancestry (other), socioeconomic position, cell composition (reference based)	Beta Values	years	Illumina HumanMethylationEPIC	Whole Blood	Not all sites reported	233	1	Adults	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.033	0.0036	6.8e-20	None	31426852_Tajuddin-SM_age_in_white_individuals
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-	-	8.28e-20	-	26857698_primary_sjogrens_syndrome_whole_blood
Battram T	GEO	30291105	2020-11-01	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE113904	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Colon, rectum	None	232	1	Adults	Both	Unclear	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0031	0.00031	1.1e-19	None	30291105_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse113904
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.09071	0.0101026	3.0638869999999995e-19	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.0728594	0.00824112	1.055607e-18	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Li S	-	28811542	2017-08-15	Age	EFO_0000246	-	Table S1	DNA methylation	Age	Cell counts	M values	years	Illumina HumanMethylation450	Whole blood	-	1366	2	73	Missing	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0253	0.00290294	1.45e-18	-	28811542_age
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg20462795	chr6:10981184	6	10981184	ELOVL2	Open sea	-0.97307022	0.1111	1.97e-18	-	25888029_ageing
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0769819	0.00878062	2.029396e-18	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	0.0720436	0.00823512	2.397688e-18	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	0.0718213	0.00823525	3.044595e-18	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0718056	0.00823526	3.096208e-18	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Battram T	GEO	29383109	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE101961	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Breast	None	121	1	Adults	Females	European, African	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.00319	0.00032	6.5e-17	None	29383109_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse101961
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.070037	0.00855044	2.801885e-16	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Tajuddin SM	HANDLS	31426852	2019-08-19	Age	EFO_0001799	In African American individuals	Table 2, Table S1	DNA methylation	Age	Sex, ancestry (other), socioeconomic position, cell composition (reference based)	Beta Values	years	Illumina HumanMethylationEPIC	Whole Blood	Not all sites reported	237	1	Adults	Both	African	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.027	0.0034	5.5e-16	None	31426852_Tajuddin-SM_age_in_african_american_individuals
Johnson KC	-	28693600	2017-07-10	Age	EFO_0000246	-	Additional file 3	DNA methylation	Age	Body mass index, parity and cell counts	M values	years	Illumina HumanMethylation450	Breast	-	100	1	37.2	Females	European,African,Admixed	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0142	0.0018	5.59e-16	-	28693600_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0687459	0.00855513	0.00000000000000100159	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.252769	0.0316657	0.000000000000001524081	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	0.0643788	0.00823944	0.000000000000005938463	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.0646035	0.0083196	0.000000000000008688271	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	0.0638317	0.00823973	0.00000000000001003787	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	0.0628431	0.00824025	0.00000000000002562703	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	0.0622835	0.00824054	0.000000000000043289	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	25888029	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE58888. Compared nonagenarians to adults aged 19-30	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	143	1	Geriatrics	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.199	0.0236	0.000000000000092	None	25888029_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse58888__compared_nonagenarians_to_adults_aged_19-30
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.0611941	0.0082411	0.0000000000001185556	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Kachroo P	None	33468710	2021-01-19	Age	EFO_0000246	Adult age	Table 2b	DNA methylation	Age	COPD disease status, sex, race, smoking, batch effects	Beta Values	years	Illumina HumanMethylation450	Lung	None	160	1	Adults	Both	Admixed	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.004	0.00054	0.00000000000015	None	33468710_Kachroo-P_age_adult_age
Kachroo P	None	33468710	2021-01-19	Age	EFO_0000246	Adult age	Table 2b	DNA methylation	Age	COPD disease status, sex, race, smoking, batch effects	Beta Values	years	Illumina HumanMethylation450	Lung	None	160	1	Adults	Both	Admixed	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.006	0.00081	0.00000000000015	None	33468710_Kachroo-P_age_adult_age
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21649660	chr6:10995125	6	10995125	ELOVL2	Open sea	0.0011	None	0.00000000000028	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0584727	0.00824244	0.000000000001361606	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	-0.0583955	0.00824248	0.000000000001456952	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0577313	0.0082428	0.000000000002598713	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20462795	chr6:10981184	6	10981184	ELOVL2	Open sea	-0.04066	0.00544	0.0000000000026	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg22143569	chr6:11044541	6	11044541	ELOVL2	Island	0.00585	8e-04	0.00000000000395	-	23334450_rheumatoid_arthritis
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.00512	0.00075	0.0000000000087	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Battram T	GEO	29383109	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE101961	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Breast	None	121	1	Adults	Females	European, African	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.00236	0.00031	0.00000000002	None	29383109_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse101961
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.448729	0.0669768	0.00000000002151971	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.056603	0.00859015	0.00000000004570503	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.0539	0.00824457	0.00000000006456311	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg16323298	chr6:11044974	6	11044974	ELOVL2	Island	0.02329	0.00338	0.000000000079	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	0.053558	0.00824472	0.00000000008512361	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08683088	chr6:11007465	6	11007465	ELOVL2	Open sea	0.002	None	0.000000000087	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg05446010	chr6:11044558	6	11044558	ELOVL2	Island	0.00462	7e-04	0.000000000119	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	-0.0655923	0.0101799	0.0000000001205523	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0526137	0.00824514	0.0000000001810079	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23642061	chr6:11043631	6	11043631	ELOVL2	North shore	-0.01779	0.00266	0.00000000024	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.052672	0.00833772	0.0000000002738364	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	0.051739	0.00824551	0.0000000003599078	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg08683088	chr6:11007465	6	11007465	ELOVL2	Open sea	-1.528745	0.2443	0.00000000039	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0514368	0.00824564	0.0000000004551923	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	-0.0514354	0.00824564	0.0000000004556891	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.196821	0.0317614	0.0000000005889621	None	39706196_Hannah-M.-Smith_body_fat_discovery
Battram T	GEO	29383109	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE101961	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Breast	None	121	1	Adults	Females	European, African	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.00252	0.00037	0.00000000061	None	29383109_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse101961
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	0.0509981	0.00824583	0.0000000006386641	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07901130	chr6:11041295	6	11041295	ELOVL2	North shelf	-0.0022	0.00036	0.00000000089	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	-0.0502009	0.00824616	0.000000001173351	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.042	0.00694	0.0000000012	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0506936	0.00837403	0.000000001450345	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.0523382	0.00868365	0.00000000170824	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.226837	0.037762	0.00000000192741	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21649660	chr6:10995125	6	10995125	ELOVL2	Open sea	0.0036	None	0.000000002	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Battram T	GEO	25888029	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE58888. Compared nonagenarians to adults aged 19-30	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	143	1	Geriatrics	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.219	0.0338	0.0000000021	None	25888029_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse58888__compared_nonagenarians_to_adults_aged_19-30
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	-0.20829	0.0350408	0.000000002831102	None	39706196_Hannah-M.-Smith_bmi_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg22143569	chr6:11044541	6	11044541	ELOVL2	Island	0.00417	0.00067	0.000000003	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0488776	0.0082467	0.000000003155812	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0488227	0.00824673	0.000000003286154	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Johnson KC	-	28693600	2017-07-10	Age	EFO_0000246	-	Additional file 3	DNA methylation	Age	Body mass index, parity and cell counts	M values	years	Illumina HumanMethylation450	Breast	-	100	1	37.2	Females	European,African,Admixed	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0232	0.004	0.00000000488	-	28693600_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0482752	0.00824694	0.00000000490989	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	-0.166822	0.0285961	0.000000005516739	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0479977	0.00824706	0.000000006008488	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Johnson KC	-	28693600	2017-07-10	Age	EFO_0000246	-	Additional file 3	DNA methylation	Age	Body mass index, parity and cell counts	M values	years	Illumina HumanMethylation450	Breast	-	100	1	37.2	Females	European,African,Admixed	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0083	0.0014	0.00000000633	-	28693600_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	-0.0581796	0.0101606	0.00000001048532	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	0.0464369	0.00824766	0.00000001831907	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.00553	0.00098	0.000000019	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	-0.0463331	0.0082477	0.00000001970355	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.0466903	0.00835372	0.00000002322355	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	0.0460495	0.00824781	0.00000002402692	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0492275	0.00881726	0.00000002404948	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0457035	0.00824794	0.00000003055764	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.0456865	0.00824795	0.00000003091994	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.036	0.00654	0.000000034	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23642061	chr6:11043631	6	11043631	ELOVL2	North shore	0.0018	None	0.000000042	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg08683088	chr6:11007465	6	11007465	ELOVL2	Open sea	-	-	0.0000000462	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	0.0449284	0.00824823	0.00000005204065	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0488031	0.00897302	0.00000005448021	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_4
Christiansen C	TwinsUK, NSHD, NCDS1, NCDS2, BCS70	33593402	2021-02-16	Smoking	EFO_0004318, EFO_0006527	Current vs never smoking meta-analysis in European samples	Table S1	DNA methylation	Smoking	Sex, cell composition (reference based), body mass index, batch effects, relatedness	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	912	5	Adults	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	None	None	0.000000059	None	33593402_Christiansen-C_smoking_current_vs_never_smoking_meta-analysis_in_european_samples
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22143569	chr6:11044541	6	11044541	ELOVL2	Island	-0.000037	0.0000069	0.000000062	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	-0.0444258	0.00824842	0.00000007316347	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05446010	chr6:11044558	6	11044558	ELOVL2	Island	0.00265	0.00047	0.000000077	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0052	0.001	0.00000008	-	27651444_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.0432103	0.00806213	0.00000008463696	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	0.0440021	0.00824857	0.0000000972266	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.195709	0.0368029	0.0000001062852	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	0.0436829	0.00824869	0.0000001202507	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	1.4	0.272	0.00000014	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Battram T	GEO	25888029	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE58888. Compared nonagenarians to adults aged 19-30	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	143	1	Geriatrics	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.117	0.0208	0.00000014	None	25888029_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse58888__compared_nonagenarians_to_adults_aged_19-30
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.298591	0.0569875	0.0000001628132	None	39706196_Hannah-M.-Smith_bmi_discovery
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.00609	0.00117	0.00000019	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0423739	0.00824916	0.000000283109	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.162661	0.0316751	0.000000284761	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0502941	0.00981113	0.0000002993681	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg13562911	chr6:11044106	6	11044106	ELOVL2	Island	1.194976	0.2343	0.000000341	-	27105112_hiv_infection_discovery
Chen S	IoW birth cohort	32190749	2020-03-12	Pubertal timing	EFO_0001382, EFO_0005677	Males only PT measured by skin change	Table S2	DNA methylation	Pubertal timing	Age, cell composition (reference based), batch effects	M Values	years	Illumina HumanMethylation450	Whole blood	None	226.07	1	Children	Males	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	None	None	0.00000035	None	32190749_Chen-S_pubertal_timing_males_only_pt_measured_by_skin_change
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16323298	chr6:11044974	6	11044974	ELOVL2	Island	-0.0045	0.00089	0.00000047	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0414695	0.00824947	0.0000005042641	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	0.155554	0.0309614	0.0000005105461	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.326861	0.0653884	0.0000005823372	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	2.1	0.412	0.00000065	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.040919	0.00824966	0.0000007125079	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.187872	0.0380196	0.0000007826813	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.332569	0.0674511	0.0000008277218	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0410893	0.00837604	0.0000009415388	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08683088	chr6:11007465	6	11007465	ELOVL2	Open sea	-0.02573	0.0051	0.000001	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.0012	0.00025	0.0000011	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	0.0401332	0.00824992	0.000001158364	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.0401253	0.00824992	0.000001163934	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	0.0401003	0.00824993	0.000001181946	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0405057	0.00835088	0.000001244332	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg04097236	chr6:11008618	6	11008618	ELOVL2	Open sea	-0.245816	0.0508906	0.000001374405	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0398338	0.00825002	0.000001390682	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0413801	0.00858559	0.000001452082	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	-0.0397489	0.00825005	0.000001464382	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	0.0397292	0.00825005	0.000001481976	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Chen S	IoW birth cohort	32190749	2020-03-12	Pubertal timing	EFO_0001382, EFO_0005677	Males only PT measured by facial hair growth	Table S2	DNA methylation	Pubertal timing	Age, cell composition (reference based), batch effects	M Values	years	Illumina HumanMethylation450	Whole blood	None	226.07	1	Children	Males	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	None	None	0.0000016	None	32190749_Chen-S_pubertal_timing_males_only_pt_measured_by_facial_hair_growth
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0470039	0.00983362	0.000001770707	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.0387748	0.00813564	0.000001896788	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg25151806	chr6:11045370	6	11045370	ELOVL2	South shore	0.01381	0.00281	0.0000019	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.039216	0.00825022	0.000002019934	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	-0.0391892	0.00825023	0.000002052731	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0486353	0.0102529	0.000002119857	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	0.0391154	0.00825025	0.000002145454	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	0.0560227	0.0118367	0.000002233429	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0015	0.00031	0.0000024	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Battram T	GEO	30291105	2020-11-01	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE113904	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Colon, rectum	None	232	1	Adults	Both	Unclear	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.00214	0.00044	0.0000025	None	30291105_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse113904
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	1.3	0.278	0.0000026	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	0.0387104	0.00825038	0.000002730604	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.160146	0.0341518	0.000002761914	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Chen S	IoW birth cohort	32190749	2020-03-12	Pubertal timing	EFO_0001382, EFO_0005677	Males only PT measured by body hair growth	Table S2	DNA methylation	Pubertal timing	Age, cell composition (reference based), batch effects	M Values	years	Illumina HumanMethylation450	Whole blood	None	226.07	1	Children	Males	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	None	None	0.0000029	None	32190749_Chen-S_pubertal_timing_males_only_pt_measured_by_body_hair_growth
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0385501	0.00825043	0.00000300212	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0385242	0.00825044	0.00000304837	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0384791	0.00825046	0.000003130478	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.0384529	0.00825047	0.000003179111	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0382604	0.00825053	0.000003559956	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	0.0380509	0.00825059	0.000004023867	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	-0.131447	0.0286723	0.00000458326	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0505112	0.01107	0.000005086028	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05446010	chr6:11044558	6	11044558	ELOVL2	Island	-0.000031	0.0000068	0.0000055	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Anna Ulrich	None	38184627	Dec 5, 2023	Idiopathic/heritable pulmonary arterial hypertension	None	Discovery	None	DNA methylation	Idiopathic/heritable pulmonary arterial hypertension	Age, Sex, Smoking, Cell composition (reference based), Ancestry (other), first ten principal components computed from control probes	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	1655	4	Adults	Both	European	cg08683088	chr6:11007465	6	11007465	ELOVL2	Open sea	-16	3.4	0.0000055	None	38184627_Anna-Ulrich_idiopathic_heritable_pulmonary_arterial_hypertension_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	-0.0373829	0.0082508	0.000005921863	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	-0.0371563	0.00825087	0.000006741568	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.044823	0.00997592	0.000007072583	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	0.0370182	0.00825091	0.000007293129	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0393769	0.00880728	0.000007845826	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0400948	0.00896817	0.000007851809	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	0.0366078	0.00825104	0.000009199339	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Chen S	IoW birth cohort	32190749	2020-03-12	Pubertal timing	EFO_0001382, EFO_0005677	Males only PT measured by voice change	Table S2	DNA methylation	Pubertal timing	Age, cell composition (reference based), batch effects	M Values	years	Illumina HumanMethylation450	Whole blood	None	226.07	1	Children	Males	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	None	None	0.0000095	None	32190749_Chen-S_pubertal_timing_males_only_pt_measured_by_voice_change
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13562911	chr6:11044106	6	11044106	ELOVL2	Island	0.00562	0.00124	0.00001	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	-0.154763	0.0350295	0.00001001934	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0387688	0.0088219	0.00001117538	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg20462795	chr6:10981184	6	10981184	ELOVL2	Open sea	-0.324089	0.074	0.0000119	None	27105112_hiv_infection_cd4_tcells
Chen S	IoW birth cohort	32190749	2020-03-12	Pubertal timing	EFO_0001382, EFO_0005677	Males only PT measured by skin change	Table S2	DNA methylation	Pubertal timing	Age, cell composition (reference based), batch effects	M Values	years	Illumina HumanMethylation450	Whole blood	None	226.07	1	Children	Males	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	None	None	0.000012	None	32190749_Chen-S_pubertal_timing_males_only_pt_measured_by_skin_change
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.174358	0.0401789	0.00001435878	None	39706196_Hannah-M.-Smith_bmi_discovery
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Age	EFO_0000246	None	Additional file 2g	DNA methylation	Age	Smoking, cell composition (reference based), batch effects	Beta Values	years	Illumina HumanMethylationEPIC	Whole blood	None	120	1	Adults	Males	African	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.00275	0.0006	0.000015	None	31910897_Cronjé-HT_age
Chen S	IoW birth cohort	32190749	2020-03-12	Pubertal timing	EFO_0001382, EFO_0005677	Males only PT measured by voice change	Table S2	DNA methylation	Pubertal timing	Age, cell composition (reference based), batch effects	M Values	years	Illumina HumanMethylation450	Whole blood	None	226.07	1	Children	Males	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	None	None	0.000016	None	32190749_Chen-S_pubertal_timing_males_only_pt_measured_by_voice_change
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.163081	0.0378879	0.00001684269	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	-0.0355155	0.00825136	0.00001686794	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Christiansen C	TwinsUK, NSHD, NCDS1, NCDS2, BCS70	33593402	2021-02-16	Smoking	EFO_0004318, EFO_0006527	Current vs never smoking meta-analysis in European samples	Table S1	DNA methylation	Smoking	Sex, cell composition (reference based), body mass index, batch effects, relatedness	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	912	5	Adults	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	None	None	0.000017	None	33593402_Christiansen-C_smoking_current_vs_never_smoking_meta-analysis_in_european_samples
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0377532	0.00880521	0.00001817665	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	-0.0390597	0.00912839	0.00001889903	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	-0.0352177	0.00825145	0.00001984125	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0350434	0.0082515	0.000021807	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	-0.91	0.215	0.000023	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Chen S	IoW birth cohort	32190749	2020-03-12	Pubertal timing	EFO_0001382, EFO_0005677	Males only PT measured by facial hair growth	Table S2	DNA methylation	Pubertal timing	Age, cell composition (reference based), batch effects	M Values	years	Illumina HumanMethylation450	Whole blood	None	226.07	1	Children	Males	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	None	None	0.000024	None	32190749_Chen-S_pubertal_timing_males_only_pt_measured_by_facial_hair_growth
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0390591	0.00926476	0.00002502941	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0365989	0.00871709	0.00002702397	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.239542	0.0571342	0.00002771174	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0469574	0.0112344	0.00002934807	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	-0.034461	0.00825167	0.0000298065	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	-0.034313	0.00825171	0.00003224592	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Caramaschi D	PACE	35145228	None	Cognitive skills -- overall score	EFO_0008354	None	None	Cognitive skills -- overall score	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Gestational age, Education, Birthweight, maternal age at delivery, gestational age at birth, parity at delivery	z-scores	Beta values	Illumina HumanMethylationEPIC and Illumina HumanMethylation450	cord blood	None	2196	7	Infants	Both	European, Admixed	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-1.99	0.48	0.000033	None	35145228_Caramaschi-D_cognitive_skills_--_overall_score
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	-0.0369318	0.00889372	0.00003306302	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.166992	0.0402728	0.00003391677	None	39706196_Hannah-M.-Smith_body_fat_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.134942	0.0326358	0.00003569614	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	-0.0340988	0.00825177	0.0000361145	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	-0.0340046	0.0082518	0.00003795078	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.93	0.226	0.000039	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.0463204	0.0112826	0.00004056729	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	-0.0451386	0.0110561	0.00004475252	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08683088	chr6:11007465	6	11007465	ELOVL2	Open sea	-0.0069	0.0017	0.000045	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.172349	0.0422459	0.00004530197	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	-0.11555	0.0284909	0.00005021145	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	-0.0356216	0.00878805	0.00005073582	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0393782	0.00971955	0.00005116543	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0397875	0.00982257	0.00005134618	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Battram T	GEO	30291105	2020-11-01	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE113904	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Colon, rectum	None	232	1	Adults	Both	Unclear	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	0.00094	0.00023	0.000052	None	30291105_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse113904
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg23642061	chr6:11043631	6	11043631	ELOVL2	North shore	None	None	0.000052	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.036317	0.00898149	0.00005291922	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0338911	0.00839171	0.00005403558	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	-0.0337705	0.00836716	0.00005462706	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0332957	0.00825199	0.00005491119	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.049	0.0121	0.000055	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0362537	0.00898801	0.00005521646	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0332207	0.00825201	0.00005707517	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	0.0614699	0.0152731	0.00005733297	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	-0.0411576	0.0102618	0.00006082372	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	INSL4 protein levels (SeqId = 6410-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	INSL4 protein levels (SeqId = 6410-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Early placenta insulin-like peptide	774	1	Adults (18-65 years)	Both	European	cg21572722	chr6:11044894	6	11044894	ELOVL2	Island	1.34	0.334	0.000061	None	Gadd-DA_insl4_protein_levels__seqid___6410-26__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01799681	chr6:11043368	6	11043368	ELOVL2	North shore	-0.0335113	0.00836502	0.00006202838	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0329726	0.00825208	0.00006482559	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	-0.0467032	0.0117348	0.00006927647	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0328176	0.00825212	0.00007016481	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23557545	chr6:11009768	6	11009768	ELOVL2	Open sea	0.0328126	0.00825213	0.00007034226	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	0.0327592	0.00825214	0.00007228206	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.0336188	0.00848631	0.0000748214	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg23476957	chr6:11006501	6	11006501	ELOVL2	Open sea	-0.92	0.233	0.000075	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	-0.0326592	0.00825217	0.00007604531	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	0.0326353	0.00825217	0.00007697403	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01799681	chr6:11043368	6	11043368	ELOVL2	North shore	-0.0330663	0.00836229	0.00007714733	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16867657	chr6:11044877	6	11044877	ELOVL2	Island	0.0353846	0.00895585	0.00007818963	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg24724428	chr6:11044888	6	11044888	ELOVL2	Island	0.12882	0.0326117	0.0000784274	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07901130	chr6:11041295	6	11041295	ELOVL2	North shelf	0.01257	0.00312	0.000079	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08683088	chr6:11007465	6	11007465	ELOVL2	Open sea	0.0097	0.0025	0.000079	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26568284	chr6:11039533	6	11039533	ELOVL2	Open sea	-0.0324388	0.00825223	0.00008501314	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18722861	chr6:11026931	6	11026931	ELOVL2	Open sea	-0.0534326	0.0136373	0.00008965275	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18000445	chr6:11032802	6	11032802	ELOVL2	Open sea	0.0322228	0.00825228	0.00009475998	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1