author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0055	0.0002	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-0.028	0.0011	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08859447	chr1:110197289	1	110197289	GSTM4	North shore	-0.0037	0.00028	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	-0.0021	0.00018	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	-0.0012	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27182047	chr1:110199061	1	110199061	GSTM4	Island	-0.0016	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg11903880	chr1:110197856	1	110197856	GSTM4	North shore	0.41073	0.00775	5.7e-117	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24481801	chr1:110197235	1	110197235	GSTM4	North shore	0.20337	0.00386	1.4e-116	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg07569194	chr1:110200960	1	110200960	GSTM4	South shore	None	None	2.2e-96	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350922__gene_symbol__gstm4__meta-analysis
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	-	-	7.63e-51	-	28056824_age_4_vs_age_0
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	None	None	3.1999999999999996e-49	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350922__gene_symbol__gstm4__meta-analysis
Xu CJ	-	28056824	2017-01-05	Age 4 vs age 0	EFO_0000246	-	Additional file 3	DNA methylation	Age 4 vs age 0	Sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood and cord blood	-	269	2	-	Both	European	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	-	-	2.3799999999999998e-48	-	28056824_age_4_vs_age_0
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.116042	0.00820079	3.693011e-45	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg24481801	chr1:110197235	1	110197235	GSTM4	North shore	-	-	5.53e-43	-	23526956_clear_cell_renal_carcinoma
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg06932256	chr1:110198347	1	110198347	GSTM4	North shore	0.03821	0.00223	1.4999999999999999e-40	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg27182047	chr1:110199061	1	110199061	GSTM4	Island	0.08315	0.00504	9e-39	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	None	None	1.1e-37	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350981__gene_symbol__gstm1__meta-analysis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	None	None	3.7e-33	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350981__gene_symbol__gstm1__meta-analysis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	None	None	5.1e-32	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350981__gene_symbol__gstm1__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.0955365	0.00821881	4.252802e-31	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.090896	0.00822239	2.690945e-28	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	0.06343	0.00489	4.500000000000001e-28	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07569194	chr1:110200960	1	110200960	GSTM4	South shore	0.03405	0.00267	2e-27	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg07569194	chr1:110200960	1	110200960	GSTM4	South shore	None	None	9e-27	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350981__gene_symbol__gstm1__meta-analysis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	None	None	4.2e-26	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350922__gene_symbol__gstm4__meta-analysis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg15069758	chr1:110198731	1	110198731	GSTM4	Island	None	None	2.2e-23	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350922__gene_symbol__gstm4__meta-analysis
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.00105192	0.00010853	2.38e-21	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	None	None	8.4e-20	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350922__gene_symbol__gstm4__meta-analysis
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	1.18955	0.10112	1.12e-19	-	25282492_fetal_vs_adult_liver
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2427208 (gene symbol: GSTM3)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2427208 (gene symbol: GSTM3)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg08859447	chr1:110197289	1	110197289	GSTM4	North shore	None	None	1.9e-19	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2427208__gene_symbol__gstm3__meta-analysis
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.00111996	0.00012201	2.24e-19	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.0722627	0.00823499	1.893698e-18	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.0719868	0.00823515	2.5488e-18	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg22439783	chr1:110201693	1	110201693	GSTM4	South shelf	None	None	2.9e-18	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350981__gene_symbol__gstm1__meta-analysis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350922 (gene symbol: GSTM4)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg06932256	chr1:110198347	1	110198347	GSTM4	North shore	None	None	3.3e-18	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350922__gene_symbol__gstm4__meta-analysis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350952 (gene symbol: GSTM2)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350952 (gene symbol: GSTM2)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	None	None	3.3e-17	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350952__gene_symbol__gstm2__meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM4 protein levels (SeqId = 18895-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM4 protein levels (SeqId = 18895-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 4	774	1	Adults (18-65 years)	Both	European	cg07569194	chr1:110200960	1	110200960	GSTM4	South shore	1.722	0.204	3.5e-17	None	Gadd-DA_gstm4_protein_levels__seqid___18895-54__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22439783	chr1:110201693	1	110201693	GSTM4	South shelf	0.00074	None	0.0000000000000025	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg22439783	chr1:110201693	1	110201693	GSTM4	South shelf	-0.01369	0.00167	0.000000000000035	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM1 protein levels (SeqId = 15395-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM1 protein levels (SeqId = 15395-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 1	774	1	Adults (18-65 years)	Both	European	cg07569194	chr1:110200960	1	110200960	GSTM4	South shore	1.54	0.204	0.000000000000041	None	Gadd-DA_gstm1_protein_levels__seqid___15395-15__somascan_protein_measurement
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg06932256	chr1:110198347	1	110198347	GSTM4	North shore	None	None	0.000000000000063	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350981__gene_symbol__gstm1__meta-analysis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350952 (gene symbol: GSTM2)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350952 (gene symbol: GSTM2)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg22439783	chr1:110201693	1	110201693	GSTM4	South shelf	None	None	0.00000000000049	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350952__gene_symbol__gstm2__meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM3 protein levels (SeqId = 9748-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM3 protein levels (SeqId = 9748-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 3	774	1	Adults (18-65 years)	Both	European	cg07569194	chr1:110200960	1	110200960	GSTM4	South shore	1.47	0.204	0.00000000000054	None	Gadd-DA_gstm3_protein_levels__seqid___9748-31__somascan_protein_measurement
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg15069758	chr1:110198731	1	110198731	GSTM4	Island	0.01612	0.0023	0.00000000000105	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0587316	0.00824232	0.00000000000108447	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13792045	chr1:110198611	1	110198611	GSTM4	Island	0.00013	None	0.0000000000044	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11903880	chr1:110197856	1	110197856	GSTM4	North shore	-0.00088	0.00013	0.0000000000058	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350952 (gene symbol: GSTM2)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350952 (gene symbol: GSTM2)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg07569194	chr1:110200960	1	110200960	GSTM4	South shore	None	None	0.0000000000094	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350952__gene_symbol__gstm2__meta-analysis
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	0.02032	0.003	0.0000000000102	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0559914	0.00824362	0.00000000001147719	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350952 (gene symbol: GSTM2)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350952 (gene symbol: GSTM2)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	None	None	0.000000000012	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350952__gene_symbol__gstm2__meta-analysis
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg08859447	chr1:110197289	1	110197289	GSTM4	North shore	-2.141002	0.3171	0.0000000000145	-	27105112_hiv_infection_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM4 protein levels (SeqId = 18895-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM4 protein levels (SeqId = 18895-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 4	774	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	1.158	0.172	0.000000000016	None	Gadd-DA_gstm4_protein_levels__seqid___18895-54__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0553515	0.00824391	0.00000000001960078	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2350981 (gene symbol: GSTM1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg27182047	chr1:110199061	1	110199061	GSTM4	Island	None	None	0.000000000021	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2350981__gene_symbol__gstm1__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.0552667	0.00824395	0.0000000000210333	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0063	0.00086	0.000000000035	None	33564054_Kashima-K_gestational_age
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08859447	chr1:110197289	1	110197289	GSTM4	North shore	0.0021	None	0.000000000043	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.053942	0.00824455	0.00000000006240327	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0535038	0.00824475	0.00000000008891781	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07351262	chr1:110198909	1	110198909	GSTM4	Island	0.00083	None	0.00000000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-0.0530557	0.00824494	0.00000000012736	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM3 protein levels (SeqId = 9748-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM3 protein levels (SeqId = 9748-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 3	774	1	Adults (18-65 years)	Both	European	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	-0.68	0.107	0.00000000015	None	Gadd-DA_gstm3_protein_levels__seqid___9748-31__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	0.0083	0.0013	0.00000000024	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	0.0057	0.0009	0.00000000024	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM4 protein levels (SeqId = 18895-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM4 protein levels (SeqId = 18895-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 4	774	1	Adults (18-65 years)	Both	European	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	-0.675	0.107	0.00000000028	None	Gadd-DA_gstm4_protein_levels__seqid___18895-54__somascan_protein_measurement
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg07569194	chr1:110200960	1	110200960	GSTM4	South shore	0.17271	0.0282	0.000000000873	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0498611	0.0082463	0.000000001516409	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2427208 (gene symbol: GSTM3)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2427208 (gene symbol: GSTM3)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	None	None	0.0000000021	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2427208__gene_symbol__gstm3__meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27182047	chr1:110199061	1	110199061	GSTM4	Island	0.0055	0.00093	0.0000000025	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg11903880	chr1:110197856	1	110197856	GSTM4	North shore	-0.01849	0.0031	0.00000000408	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.0483749	0.00824691	0.000000004565172	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0483191	0.00824693	0.00000000475508	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.0480917	0.00824702	0.000000005611784	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.04802	0.00824705	0.000000005911757	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0479307	0.00824708	0.000000006307382	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0472365	0.00824735	0.00000001039356	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	1.7	0.294	0.000000019	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0057	0.001	0.00000002	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01564068	chr1:110198568	1	110198568	GSTM4	Island	0.00702	0.00122	0.000000037	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.0440741	0.00824855	0.0000000926532	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0432677	0.00824884	0.0000001581939	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0769868	0.0150325	0.0000003034	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	-0.0098	0.0019	0.00000032	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.04215	0.00824923	0.0000003269467	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg22711251	chr1:110198809	1	110198809	GSTM4	Island	0.155612	0.0305612	0.000000358183	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0418754	0.00824933	0.0000003897426	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	None	None	0.00000055	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM3 protein levels (SeqId = 9748-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM3 protein levels (SeqId = 9748-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 3	774	1	Adults (18-65 years)	Both	European	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	-0.69	0.139	0.00000067	None	Gadd-DA_gstm3_protein_levels__seqid___9748-31__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07569194	chr1:110200960	1	110200960	GSTM4	South shore	-0.00053	0.00011	0.00000086	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0403257	0.00824986	0.000001029195	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM1 protein levels (SeqId = 15395-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM1 protein levels (SeqId = 15395-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 1	774	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.84	0.172	0.0000011	None	Gadd-DA_gstm1_protein_levels__seqid___15395-15__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22439783	chr1:110201693	1	110201693	GSTM4	South shelf	-0.00041	0.000087	0.0000017	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0392039	0.00825022	0.000002034669	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-0.0394356	0.00833173	0.000002230949	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0390194	0.00825028	0.000002272186	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.165321	0.0349722	0.000002293155	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.0389661	0.0082503	0.00000234559	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-0.216008	0.0459841	0.000002653499	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-0.0385668	0.00825043	0.000002972659	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM3 protein levels (SeqId = 9748-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM3 protein levels (SeqId = 9748-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 3	774	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.79	0.172	0.0000042	None	Gadd-DA_gstm3_protein_levels__seqid___9748-31__somascan_protein_measurement
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	1.4	0.302	0.0000046	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.0377232	0.00825069	0.000004867577	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0381187	0.00834725	0.000004996984	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0095	0.0021	0.0000067	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15069758	chr1:110198731	1	110198731	GSTM4	Island	0.0371341	0.00825088	0.000006827439	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.037386	0.00835827	0.000007773429	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Joubert BR	PACE	27040690	2016-04-07	Maternal smoking in pregnancy	EFO_0006527, EFO_0005671, EFO_0004318, EFO_0002950	Any maternal smoking in pregnancy effect on newborns	Table S3	DNA methylation	Maternal smoking in pregnancy	Maternal age, maternal education, parity and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	6685	13	0	Missing	European,East Asian,African,Admixed,Other	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-0.007	0.002	0.000008	-	27040690_maternal_smoking_in_pregnancy_any_maternal_smoking_in_pregnancy_effect_on_newborns
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous decade consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	None	None	0.000008	None	31789449_Dugue-P-A_alcohol_consumption_previous_decade_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.036347	0.00825112	0.00001064842	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24481801	chr1:110197235	1	110197235	GSTM4	North shore	-0.00058	0.00013	0.000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM1 protein levels (SeqId = 15395-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM1 protein levels (SeqId = 15395-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 1	774	1	Adults (18-65 years)	Both	European	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	-0.47	0.107	0.000012	None	Gadd-DA_gstm1_protein_levels__seqid___15395-15__somascan_protein_measurement
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-	-	0.0000127	-	26500701_sex_kora_f4
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTM4 protein levels (SeqId = 18895-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTM4 protein levels (SeqId = 18895-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase Mu 4	774	1	Adults (18-65 years)	Both	European	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	-0.604	0.139	0.000014	None	Gadd-DA_gstm4_protein_levels__seqid___18895-54__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	-0.0356333	0.00825133	0.00001581276	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0426863	0.0099315	0.00001733977	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Joubert BR	PACE	27040690	2016-04-07	Maternal smoking in pregnancy	EFO_0006527, EFO_0005671, EFO_0004318, EFO_0002950	Sustained maternal smoking in pregnancy effect on newborns	Table S3	DNA methylation	Maternal smoking in pregnancy	Maternal age, maternal education, parity and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	5647	9	0	Missing	European,African,Admixed,Other	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-0.008	0.002	0.0000225	-	27040690_maternal_smoking_in_pregnancy_sustained_maternal_smoking_in_pregnancy_effect_on_newborns
Gadd DA	Generation Scotland	35945220	31/07/2022	TP53 protein levels (SeqId = 6123-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TP53 protein levels (SeqId = 6123-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cellular tumor antigen p53	774	1	Adults (18-65 years)	Both	European	cg15069758	chr1:110198731	1	110198731	GSTM4	Island	-0.91	0.215	0.000023	None	Gadd-DA_tp53_protein_levels__seqid___6123-69__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07569194	chr1:110200960	1	110200960	GSTM4	South shore	0.0327152	0.00797677	0.00004130247	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21451998	chr1:110198240	1	110198240	GSTM4	North shore	-0.01973	0.00471	0.000043	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11585284	chr1:110201343	1	110201343	GSTM4	South shelf	0.0335571	0.00825192	0.00004795817	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13792045	chr1:110198611	1	110198611	GSTM4	Island	0.00453	0.00109	0.00005	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Lifetime consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	None	None	0.000057	None	31789449_Dugue-P-A_alcohol_consumption_lifetime_consumption_discovery
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg27182047	chr1:110199061	1	110199061	GSTM4	Island	-0.00044	0.00011	0.000062	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21460053	chr1:110198853	1	110198853	GSTM4	Island	-0.000037	0.0000094	0.000066	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0326832	0.00820946	0.00006891007	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-0.0331675	0.00835049	0.00007163486	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	0.0330057	0.00831803	0.00007283247	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-0.0330482	0.00836043	0.00007756014	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05793930	chr1:110204227	1	110204227	GSTM4	Open sea	-0.0323183	0.00825226	0.00009032417	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	LYVE1 protein levels (SeqId = 3206-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LYVE1 protein levels (SeqId = 3206-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lymphatic vessel endothelial hyaluronic acid receptor 1	774	1	Adults (18-65 years)	Both	European	cg22247664	chr1:110199126	1	110199126	GSTM4	Island	-0.42	0.107	0.000095	None	Gadd-DA_lyve1_protein_levels__seqid___3206-4__somascan_protein_measurement