author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05655707	chr11:18477254	11	18477254	LDHAL6A	North shore	-0.0016	0.00018	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05655707	chr11:18477254	11	18477254	LDHAL6A	North shore	-0.039	0.0026	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06588556	chr11:18477299	11	18477299	LDHAL6A	Island	-0.084	0.0053	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06888460	chr11:18477303	11	18477303	LDHAL6A	Island	-0.068	0.0041	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07915343	chr11:18477680	11	18477680	LDHAL6A	Island	-0.046	0.0038	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14813083	chr11:18477280	11	18477280	LDHAL6A	North shore	-0.05	0.0033	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15463284	chr11:18477534	11	18477534	LDHAL6A	Island	-0.064	0.004	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18888461	chr11:18477379	11	18477379	LDHAL6A	Island	-0.056	0.0039	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23797887	chr11:18477753	11	18477753	LDHAL6A	Island	-0.041	0.0027	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26279282	chr11:18481032	11	18481032	LDHAL6A	South shelf	-0.00081	0.000083	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26740318	chr11:18477153	11	18477153	LDHAL6A	North shore	-0.0027	0.00028	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26740318	chr11:18477153	11	18477153	LDHAL6A	North shore	-0.062	0.004	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27316453	chr11:18476131	11	18476131	LDHAL6A	North shore	-0.0021	0.000083	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24124284	chr11:18476081	11	18476081	LDHAL6A	North shore	0.10489	0.00361	1.8e-72	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27316453	chr11:18476131	11	18476131	LDHAL6A	North shore	0.0011	None	1.2e-63	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg27316453	chr11:18476131	11	18476131	LDHAL6A	North shore	0.09486	0.00513	1.3000000000000002e-44	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg18888461	chr11:18477379	11	18477379	LDHAL6A	Island	-	-	1.04e-25	-	26500701_sex_kora_f4
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg15463284	chr11:18477534	11	18477534	LDHAL6A	Island	None	None	1.0999999999999999e-25	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3322807__gene_symbol__ldhc__meta-analysis
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg06888460	chr11:18477303	11	18477303	LDHAL6A	Island	-	-	2.11e-24	-	26500701_sex_kora_f4
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg06588556	chr11:18477299	11	18477299	LDHAL6A	Island	-	-	4.1699999999999996e-24	-	26500701_sex_kora_f4
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05655707	chr11:18477254	11	18477254	LDHAL6A	North shore	-0.05238	0.00458	1.8e-23	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26740318	chr11:18477153	11	18477153	LDHAL6A	North shore	0.0771	0.00686	7.4e-23	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26740318	chr11:18477153	11	18477153	LDHAL6A	North shore	0.0035	None	1.3e-22	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg14813083	chr11:18477280	11	18477280	LDHAL6A	North shore	-	-	1.85e-22	-	26500701_sex_kora_f4
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg23797887	chr11:18477753	11	18477753	LDHAL6A	Island	-	-	8.04e-22	-	26500701_sex_kora_f4
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg06888460	chr11:18477303	11	18477303	LDHAL6A	Island	None	None	9.7e-21	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3322807__gene_symbol__ldhc__meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05655707	chr11:18477254	11	18477254	LDHAL6A	North shore	0.0023	None	1.7e-20	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07915343	chr11:18477680	11	18477680	LDHAL6A	Island	0.0595	0.00581	6e-20	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg06588556	chr11:18477299	11	18477299	LDHAL6A	Island	None	None	3.3e-19	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3322807__gene_symbol__ldhc__meta-analysis
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg15463284	chr11:18477534	11	18477534	LDHAL6A	Island	-	-	2.7e-18	-	26500701_sex_kora_f4
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg26740318	chr11:18477153	11	18477153	LDHAL6A	North shore	-	-	7.85e-18	-	26500701_sex_kora_f4
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg05655707	chr11:18477254	11	18477254	LDHAL6A	North shore	-	-	1.61e-17	-	26500701_sex_kora_f4
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg26740318	chr11:18477153	11	18477153	LDHAL6A	North shore	None	None	4.3e-17	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3322807__gene_symbol__ldhc__meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06888460	chr11:18477303	11	18477303	LDHAL6A	Island	0.0028	None	1.4e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg14813083	chr11:18477280	11	18477280	LDHAL6A	North shore	None	None	2e-16	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3322807__gene_symbol__ldhc__meta-analysis
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg02256315	chr11:18500649	11	18500649	LDHAL6A	Open sea	-2.484515	0.3046	3.48e-16	-	27105112_hiv_infection_discovery
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3322807 (gene symbol: LDHC)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg18888461	chr11:18477379	11	18477379	LDHAL6A	Island	None	None	5.6e-16	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3322807__gene_symbol__ldhc__meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06588556	chr11:18477299	11	18477299	LDHAL6A	Island	0.0036	None	0.000000000000005	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	0.0626949	0.00824033	0.00000000000002945765	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg07915343	chr11:18477680	11	18477680	LDHAL6A	Island	-	-	0.0000000000000364	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	-0.0594644	0.00824196	0.0000000000005664316	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15463284	chr11:18477534	11	18477534	LDHAL6A	Island	0.0025	None	0.00000000000057	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18888461	chr11:18477379	11	18477379	LDHAL6A	Island	0.0027	None	0.000000000016	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24124284	chr11:18476081	11	18476081	LDHAL6A	North shore	-0.0013	0.00019	0.000000000018	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Shah S	-	25249537	2014-09-23	Sex	PATO_0000047	Replication	Table S3	DNA methylation	Sex	Smoking, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	445	1	79	Both	European	cg05655707	chr11:18477254	11	18477254	LDHAL6A	North shore	-	-	0.0000000000272	-	25249537_sex_replication
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26279282	chr11:18481032	11	18481032	LDHAL6A	South shelf	-0.01504	0.00234	0.0000000011	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg24124284	chr11:18476081	11	18476081	LDHAL6A	North shore	-1.75349	0.2997	0.00000000489	-	27105112_hiv_infection_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14813083	chr11:18477280	11	18477280	LDHAL6A	North shore	0.0021	None	0.0000000081	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Shah S	-	25249537	2014-09-23	Sex	PATO_0000047	Replication	Table S3	DNA methylation	Sex	Smoking, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	445	1	79	Both	European	cg18888461	chr11:18477379	11	18477379	LDHAL6A	Island	-	-	0.0000000149	-	25249537_sex_replication
Shah S	-	25249537	2014-09-23	Sex	PATO_0000047	Replication	Table S3	DNA methylation	Sex	Smoking, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	445	1	79	Both	European	cg15463284	chr11:18477534	11	18477534	LDHAL6A	Island	-	-	0.0000000209	-	25249537_sex_replication
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06888460	chr11:18477303	11	18477303	LDHAL6A	Island	-0.0013	0.00023	0.000000023	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Shah S	-	25249537	2014-09-23	Sex	PATO_0000047	Discovery	Table S3	DNA methylation	Sex	Smoking, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	815	1	70	Both	European	cg15463284	chr11:18477534	11	18477534	LDHAL6A	Island	-	-	0.0000000473	-	25249537_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18888461	chr11:18477379	11	18477379	LDHAL6A	Island	-0.0015	0.00028	0.000000048	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Shah S	-	25249537	2014-09-23	Sex	PATO_0000047	Discovery	Table S3	DNA methylation	Sex	Smoking, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	815	1	70	Both	European	cg05655707	chr11:18477254	11	18477254	LDHAL6A	North shore	-	-	0.0000000659	-	25249537_sex_discovery
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg22731558	chr11:18483771	11	18483771	LDHAL6A	Open sea	-1.272056	0.2374	0.0000000837	-	27105112_hiv_infection_discovery
Shah S	-	25249537	2014-09-23	Sex	PATO_0000047	Discovery	Table S3	DNA methylation	Sex	Smoking, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	815	1	70	Both	European	cg18888461	chr11:18477379	11	18477379	LDHAL6A	Island	-	-	0.000000116	-	25249537_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07915343	chr11:18477680	11	18477680	LDHAL6A	Island	-0.0016	0.00031	0.00000018	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07915343	chr11:18477680	11	18477680	LDHAL6A	Island	0.0025	None	0.00000025	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	0.0423756	0.00824916	0.0000002827978	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06588556	chr11:18477299	11	18477299	LDHAL6A	Island	-0.0017	0.00033	0.00000031	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26279282	chr11:18481032	11	18481032	LDHAL6A	South shelf	0.041388	0.0082495	0.0000005309052	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07659911	chr11:18481309	11	18481309	LDHAL6A	South shelf	-0.040387	0.00824984	0.0000009910039	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	0.040074	0.00824994	0.000001201098	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23797887	chr11:18477753	11	18477753	LDHAL6A	Island	0.02785	0.00558	0.0000013	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Fernandez-Jimenez N	Pregnancy And Childhood Epigenetics (PACE)	None	None	maternal pre-pregnancy body mass index	EFO_0004340	inverse variance-weighted fixed effects meta-analysis adjusted by cellular heterogeneity	https://doi.org/10.5281/zenodo.7314534	DNA methylation	maternal pre-pregnancy body mass index	Cell composition (reference free), maternal age, parity, maternal education, maternal smoking	Beta values	kg/m2	Illumina HumanMethylation450	Placenta	None	2631	10	Infants	Both	European, Unclear	cg05655707	chr11:18477254	11	18477254	LDHAL6A	North shore	0.0013	0.00027	0.0000017	None	Fernandez-Jimenez-N_maternal_pre-pregnancy_body_mass_index_inverse_variance-weighted_fixed_effects_meta-analysis_adjusted_by_cellular_heterogeneity
Fernandez-Jimenez N	Pregnancy And Childhood Epigenetics (PACE)	None	None	maternal pre-pregnancy body mass index	EFO_0004340	inverse variance-weighted fixed effects meta-analysis	https://doi.org/10.5281/zenodo.7314534	DNA methylation	maternal pre-pregnancy body mass index	Maternal age, parity, maternal education, maternal smoking	Beta values	kg/m2	Illumina HumanMethylation450	Placenta	None	2631	10	Infants	Both	European, Unclear	cg05655707	chr11:18477254	11	18477254	LDHAL6A	North shore	0.0015	0.00031	0.0000018	None	Fernandez-Jimenez-N_maternal_pre-pregnancy_body_mass_index_inverse_variance-weighted_fixed_effects_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02256315	chr11:18500649	11	18500649	LDHAL6A	Open sea	-0.0012	0.00025	0.0000027	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02256315	chr11:18500649	11	18500649	LDHAL6A	Open sea	0.0017	None	0.0000074	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	CRISP2 protein levels (SeqId = 9282-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRISP2 protein levels (SeqId = 9282-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cysteine-rich secretory protein 2	774	1	Adults (18-65 years)	Both	European	cg26740318	chr11:18477153	11	18477153	LDHAL6A	North shore	-0.32	0.071	0.0000075	None	Gadd-DA_crisp2_protein_levels__seqid___9282-12__somascan_protein_measurement
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F3	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	53	Both	European	cg15463284	chr11:18477534	11	18477534	LDHAL6A	Island	-	-	0.00000885	-	26500701_sex_kora_f3
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F3	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	53	Both	European	cg23797887	chr11:18477753	11	18477753	LDHAL6A	Island	-	-	0.00000992	-	26500701_sex_kora_f3
Gadd DA	Generation Scotland	35945220	31/07/2022	CRISP2 protein levels (SeqId = 9282-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRISP2 protein levels (SeqId = 9282-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cysteine-rich secretory protein 2	774	1	Adults (18-65 years)	Both	European	cg18888461	chr11:18477379	11	18477379	LDHAL6A	Island	-0.31	0.072	0.000014	None	Gadd-DA_crisp2_protein_levels__seqid___9282-12__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	0.0358451	0.00825127	0.00001407302	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27316453	chr11:18476131	11	18476131	LDHAL6A	North shore	0.0023	None	0.000017	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	-0.035314	0.00825142	0.000018829	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F3	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	53	Both	European	cg26740318	chr11:18477153	11	18477153	LDHAL6A	North shore	-	-	0.0000195	-	26500701_sex_kora_f3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26279282	chr11:18481032	11	18481032	LDHAL6A	South shelf	0.035207	0.00825145	0.00001995729	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ASIC4 protein levels (SeqId = 6951-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASIC4 protein levels (SeqId = 6951-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acid-sensing ion channel 4	774	1	Adults (18-65 years)	Both	European	cg22731558	chr11:18483771	11	18483771	LDHAL6A	Open sea	-0.662	0.158	0.000028	None	Gadd-DA_asic4_protein_levels__seqid___6951-26__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	-0.0373794	0.00893874	0.0000290983	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CRISP2 protein levels (SeqId = 9282-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRISP2 protein levels (SeqId = 9282-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cysteine-rich secretory protein 2	774	1	Adults (18-65 years)	Both	European	cg15463284	chr11:18477534	11	18477534	LDHAL6A	Island	-0.22	0.053	0.000032	None	Gadd-DA_crisp2_protein_levels__seqid___9282-12__somascan_protein_measurement
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F3	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	53	Both	European	cg14813083	chr11:18477280	11	18477280	LDHAL6A	North shore	-	-	0.0000337	-	26500701_sex_kora_f3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15463284	chr11:18477534	11	18477534	LDHAL6A	Island	-0.00097	0.00024	0.000046	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F3	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	53	Both	European	cg18888461	chr11:18477379	11	18477379	LDHAL6A	Island	-	-	0.0000481	-	26500701_sex_kora_f3
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F3	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	53	Both	European	cg06588556	chr11:18477299	11	18477299	LDHAL6A	Island	-	-	0.0000504	-	26500701_sex_kora_f3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26279282	chr11:18481032	11	18481032	LDHAL6A	South shelf	-0.033382	0.00825197	0.0000525166	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	0.0333428	0.00825198	0.00005358933	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Tobi EW	PACE, PREciSE	None	2021-12-10	maternal insulin	CHEBI_5931, EFO_0004467	fasting insulin meta-EWAS	https://doi.org/10.5281/zenodo.5886997	DNA methylation	maternal insulin	Sex, Cell composition (reference based), Batch effects, Gestational age, gestational age at glycemic measurement, parity, maternal age	Beta values	log2(pmol/L)	Illumina HumanMethylation450, Illumina HumanMethylationEPIC	cord blood	meta-EWAS of exposure in utero	961	2	Infants	Both	European, South Asian, Other	cg05655707	chr11:18477254	11	18477254	LDHAL6A	North shore	0.00623	0.00154	0.000055	+ | + | 961	Tobi-EW_maternal_insulin_fasting_insulin_meta-ewas
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	-0.0332469	0.00825201	0.00005630984	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23797887	chr11:18477753	11	18477753	LDHAL6A	Island	0.0013	None	0.000073	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F3	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	53	Both	European	cg06888460	chr11:18477303	11	18477303	LDHAL6A	Island	-	-	0.0000735	-	26500701_sex_kora_f3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	-0.0354464	0.00894297	0.00007417844	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	TACSTD2 protein levels (SeqId = 2619-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TACSTD2 protein levels (SeqId = 2619-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor-associated calcium signal transducer 2	774	1	Adults (18-65 years)	Both	European	cg22731558	chr11:18483771	11	18483771	LDHAL6A	Open sea	-0.63	0.158	0.000076	None	Gadd-DA_tacstd2_protein_levels__seqid___2619-72__somascan_protein_measurement
Battram T	GEO	23334450	2020-09-15	Rheumatoid arthritis	EFO_0000685	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE42861	None	DNA methylation	Rheumatoid arthritis	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	689	1	Adults	Both	European	cg24124284	chr11:18476081	11	18476081	LDHAL6A	North shore	-0.0181	0.00456	0.000081	None	23334450_Battram-T_rheumatoid_arthritis_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse42861
Gadd DA	Generation Scotland	35945220	31/07/2022	KLK5 protein levels (SeqId = 3201-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLK5 protein levels (SeqId = 3201-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kallikrein-5	774	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	0.56	0.14	0.000092	None	Gadd-DA_klk5_protein_levels__seqid___3201-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PEX14 protein levels (SeqId = 8300-82)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PEX14 protein levels (SeqId = 8300-82)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxisomal membrane protein PEX14	774	1	Adults (18-65 years)	Both	European	cg27490103	chr11:18478792	11	18478792	LDHAL6A	South shore	-0.57	0.147	0.000095	None	Gadd-DA_pex14_protein_levels__seqid___8300-82__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26447597	chr11:18493619	11	18493619	LDHAL6A	Open sea	-0.0413832	0.0106267	0.00009893359	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_4