author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00119073	chr3:187870713	3	187870713	LPP	North shore	-0.0039	0.00029	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00119073	chr3:187870713	3	187870713	LPP	North shore	0.019	0.0018	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01356198	chr3:187929513	3	187929513	LPP	Open sea	-0.00076	0.00007	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01720795	chr3:187879604	3	187879604	LPP	Open sea	-0.00047	0.000053	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0039	0.00025	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02904838	chr3:187871519	3	187871519	LPP	Island	-0.00012	0.000013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04423294	chr3:188479059	3	188479059	LPP	Open sea	-0.0019	0.00018	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.0024	0.00024	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0013	0.000095	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05548945	chr3:188550738	3	188550738	LPP	Open sea	-0.001	0.000095	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.0025	0.00017	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05707781	chr3:188464815	3	188464815	LPP	Open sea	-0.0028	0.00027	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06645975	chr3:188020837	3	188020837	LPP	Open sea	-0.0013	0.00016	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.018	0.0018	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07196133	chr3:188439649	3	188439649	LPP	Open sea	-0.00066	0.000063	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10339098	chr3:188313650	3	188313650	LPP	Open sea	-0.00062	0.000073	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12297546	chr3:187938319	3	187938319	LPP	Open sea	-0.001	0.0001	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12298996	chr3:188272255	3	188272255	LPP	Open sea	-0.0017	0.0002	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13282252	chr3:188581493	3	188581493	LPP	Open sea	-0.0008	0.000089	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.0035	0.00021	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	0.012	0.0013	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15048700	chr3:188037871	3	188037871	LPP	Open sea	-0.0015	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0018	0.00019	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	-0.001	0.00012	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0042	0.00018	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.023	0.0011	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16915803	chr3:187909561	3	187909561	LPP	Open sea	-0.0013	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0017	0.00018	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18188653	chr3:188296976	3	188296976	LPP	Open sea	-0.00084	0.000098	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18603679	chr3:188247767	3	188247767	LPP	Open sea	-0.0026	0.00026	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19756112	chr3:188200427	3	188200427	LPP	Open sea	-0.0019	0.00022	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24123854	chr3:187973091	3	187973091	LPP	Open sea	-0.0014	0.00013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0028	0.00023	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.015	0.0016	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26318252	chr3:188281073	3	188281073	LPP	Open sea	-0.0021	0.00017	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27322975	chr3:188354136	3	188354136	LPP	Open sea	-0.0011	0.000098	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	0.57151	0.00606	2.4e-163	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	0.41993	0.00515	1.4999999999999999e-151	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.38343	0.00477	2.6e-150	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.39969	0.00514	1.2e-147	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04423294	chr3:188479059	3	188479059	LPP	Open sea	0.46395	0.00648	5.8e-141	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.25888	0.00365	3.3e-140	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	0.623	0.00889	3.1e-139	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.50592	0.00723	4.3999999999999995e-139	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.23634	0.00369	4.6e-132	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.50449	0.00814	2.4999999999999998e-129	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05548945	chr3:188550738	3	188550738	LPP	Open sea	0.63424	0.01046	1.3e-127	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg17809494	chr3:188572244	3	188572244	LPP	Open sea	0.62557	0.01159	2.2000000000000003e-118	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.58399	0.01108	1.4999999999999999e-116	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12297546	chr3:187938319	3	187938319	LPP	Open sea	0.23224	0.00478	3.9e-110	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.17829	0.00812429	4.675417e-105	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.17702	0.00812618	1.434759e-103	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.175068	0.00812906	2.635913e-101	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.174259	0.00813024	2.2438379999999999e-100	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21427213	chr3:187872975	3	187872975	LPP	South shore	0.23515	0.00568	5.9e-98	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg00119073	chr3:187870713	3	187870713	LPP	North shore	0.22196	0.00548	2.5999999999999998e-96	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.166345	0.00814154	1.6387539999999998e-91	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05762680	chr3:188405973	3	188405973	LPP	Open sea	0.25958	0.00698	5.6e-90	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.164438	0.00814418	1.927185e-89	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.163546	0.0081454	1.758263e-88	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.162926	0.00814625	8.111495e-88	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.161766	0.00814783	1.393247e-86	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19528963	chr3:187941999	3	187941999	LPP	Open sea	0.19898	0.00571	3.0999999999999997e-85	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.158537	0.00815215	3.420729e-83	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.08483	0.00256	1.3e-81	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	0.13059	0.00394	1.5e-81	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.155948	0.00815555	1.585638e-80	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.154235	0.00815778	8.700777e-79	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.153162	0.00815915	1.043379e-77	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.37306	0.01244	1.4000000000000001e-74	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.149401	0.00816391	5.479785e-74	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.148908	0.00816452	1.655595e-73	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.146577	0.00816739	2.94299e-71	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.145678	0.00816849	2.121207e-70	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.27103	0.00987	1.4999999999999998e-68	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.142117	0.00817277	4.691243e-67	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.141794	0.00817315	9.332335e-67	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.141305	0.00817373	2.638052e-66	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.141153	0.0081739	3.6420430000000003e-66	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.139641	0.00817568	8.828207e-65	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.137712	0.00817791	4.890479e-63	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.137614	0.00817802	5.989859e-63	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.135622	0.00818029	3.552769e-61	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.135028	0.00818096	1.1861210000000001e-60	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.134911	0.00818109	1.501066e-60	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.1348	0.00818121	1.882414e-60	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.133584	0.00818257	2.170996e-59	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.132148	0.00818416	3.789136e-58	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	3.7	0.232	5.4000000000000005e-58	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.131777	0.00818457	7.897482999999999e-58	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.131572	0.00818479	1.1835009999999999e-57	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.131131	0.00818528	2.82106e-57	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-	-	3.5500000000000004e-57	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.130923	0.0081855	4.239139e-57	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.130264	0.00818622	1.539051e-56	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.129495	0.00818705	6.873913e-56	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.128666	0.00818794	3.41459e-55	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.128571	0.00818804	4.1007790000000005e-55	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.127778	0.00818889	1.877344e-54	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.126526	0.00819022	2.037338e-53	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.125485	0.00819131	1.45145e-52	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.124478	0.00819235	9.52966e-52	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.123289	0.00819358	8.641095e-51	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.123228	0.00819364	9.666084e-51	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.123127	0.00819375	1.164778e-50	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.122908	0.00819397	1.74135e-50	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.122654	0.00819423	2.7801789999999995e-50	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.121324	0.00819558	3.14389e-49	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21779805	chr3:187982495	3	187982495	LPP	Open sea	0.1054	0.00525	3.5e-49	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg00869941	chr3:187929592	3	187929592	LPP	Open sea	-	-	5.86e-49	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.120145	0.00819676	2.6444219999999998e-48	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.119702	0.00819721	5.848416e-48	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.118332	0.00819856	6.701343e-47	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.118087	0.0081988	1.032629e-46	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.117843	0.00819904	1.586398e-46	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg18188653	chr3:188296976	3	188296976	LPP	Open sea	3.06636	0.10825	1.0899999999999999e-45	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.115921	0.00820091	4.554646e-45	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.115613	0.00820121	7.766001e-45	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg01356198	chr3:187929513	3	187929513	LPP	Open sea	-	-	1.1e-44	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.115154	0.00820165	1.714065e-44	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	-2.05949	0.07541	1.91e-44	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.115006	0.00820179	2.209994e-44	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.114755	0.00820203	3.399854e-44	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.114749	0.00820203	3.4373229999999997e-44	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18188653	chr3:188296976	3	188296976	LPP	Open sea	0.09339	0.00513	8.5e-44	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.113949	0.00820279	1.34733e-43	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.112606	0.00820406	1.306455e-42	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.112192	0.00820444	2.617293e-42	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.111197	0.00820537	1.377734e-41	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.110428	0.00820607	4.910605999999999e-41	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.110293	0.0082062	6.13563e-41	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.109736	0.00820671	1.531862e-40	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg18188653	chr3:188296976	3	188296976	LPP	Open sea	-	-	1.8799999999999997e-40	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.109416	0.008207	2.586906e-40	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.109091	0.00820729	4.396002e-40	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.109054	0.00820733	4.664789e-40	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24123854	chr3:187973091	3	187973091	LPP	Open sea	0.0015	None	6.3e-40	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.11133	0.00661	9.2e-40	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.108253	0.00820805	1.712886e-39	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.107563	0.00820867	5.1965499999999995e-39	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.10741	0.00820881	6.649147000000001e-39	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.001	None	1.3e-38	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.10666	0.00820947	2.2036059999999998e-38	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.106373	0.00820973	3.4792349999999997e-38	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.607437	0.0471042	7.121335e-38	None	39706196_Hannah-M.-Smith_bmi_discovery
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg21427213	chr3:187872975	3	187872975	LPP	South shore	2.51958	0.11254	7.19e-38	-	25282492_fetal_vs_adult_liver
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-	-	8.8e-38	-	23526956_clear_cell_renal_carcinoma
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-3.9	0.301	1.4e-37	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.105189	0.00821077	2.254022e-37	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.104803	0.0082111	4.124331e-37	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.104678	0.00821121	5.012889e-37	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	2.479	0.11468	9.660000000000001e-37	-	25282492_fetal_vs_adult_liver
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg20893542	chr3:187929286	3	187929286	LPP	Open sea	-	-	1.15e-36	-	23526956_clear_cell_renal_carcinoma
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	2.50334	0.11656	1.55e-36	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.103742	0.00821202	2.151567e-36	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.408003	0.0327186	1.546427e-35	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.102215	0.00821333	2.245186e-35	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	-0.02329	0.00152	2.7e-35	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.101816	0.00821366	4.119242e-35	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg27322975	chr3:188354136	3	188354136	LPP	Open sea	0.03399	0.00223	6.5e-35	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.101483	0.00821394	6.823852e-35	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.101035	0.00821432	1.342623e-34	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07196133	chr3:188439649	3	188439649	LPP	Open sea	0.00069	None	1.4e-34	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.100594	0.00821469	2.6062500000000004e-34	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07196133	chr3:188439649	3	188439649	LPP	Open sea	-0.03112	0.00209	5.700000000000001e-34	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0997375	0.0082154	9.375761e-34	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.099641	0.00821548	1.0821710000000001e-33	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0995413	0.00821556	1.254982e-33	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0991075	0.00821592	2.3864070000000003e-33	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0989607	0.00821604	2.963988e-33	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0974249	0.00821729	2.809748e-32	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-	-	3.3e-32	-	23526956_clear_cell_renal_carcinoma
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg17392043	chr3:188495102	3	188495102	LPP	Open sea	1.97701	0.10594	3.66e-32	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg05707781	chr3:188464815	3	188464815	LPP	Open sea	2.07396	0.11205	6.450000000000001e-32	-	25282492_fetal_vs_adult_liver
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg04952622	chr3:188067331	3	188067331	LPP	Open sea	-	-	1.7900000000000002e-31	-	23526956_clear_cell_renal_carcinoma
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.403846	0.0345628	2.009587e-31	None	39706196_Hannah-M.-Smith_bmi_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26318252	chr3:188281073	3	188281073	LPP	Open sea	0.0018	None	4.3e-31	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.0952821	0.00821901	6.107766e-31	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0951219	0.00821913	7.666731000000001e-31	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0947975	0.00821939	1.213677e-30	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg10149889	chr3:187930530	3	187930530	LPP	Open sea	-	-	1.99e-30	-	23526956_clear_cell_renal_carcinoma
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg12297546	chr3:187938319	3	187938319	LPP	Open sea	-	-	2.33e-30	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0942142	0.00821985	2.7612749999999997e-30	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0938242	0.00822015	4.770794e-30	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0935002	0.0082204	7.500634e-30	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0933497	0.00822052	9.249464e-30	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21176488	chr3:188251742	3	188251742	LPP	Open sea	0.0485	0.00362	2.1e-29	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.0925852	0.00822111	2.669196e-29	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0925264	0.00822115	2.894958e-29	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	1.67774	0.0998	4.5800000000000004e-29	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0921037	0.00822148	5.180309e-29	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0918875	0.00822164	6.968369e-29	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0917915	0.00822171	7.947734000000001e-29	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg06547766	chr3:187930704	3	187930704	LPP	Open sea	-	-	8.21e-29	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0917611	0.00822174	8.284685e-29	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0917576	0.00822174	8.325079e-29	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14466506	chr3:188390968	3	188390968	LPP	Open sea	0.03025	0.00229	1.0000000000000001e-28	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.091379	0.00822203	1.395936e-28	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0913013	0.00822209	1.5516120000000001e-28	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0912824	0.0082221	1.5921470000000002e-28	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0909815	0.00822233	2.3963800000000002e-28	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	0.0909687	0.00822234	2.4381600000000003e-28	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15423781	chr3:188027117	3	188027117	LPP	Open sea	-0.03531	0.00272	4.3e-28	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0902965	0.00822284	6.047746e-28	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0900359	0.00822304	8.585283e-28	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18188653	chr3:188296976	3	188296976	LPP	Open sea	0.00098	None	1e-27	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0897398	0.00822326	1.276817e-27	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0895642	0.00822339	1.61452e-27	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0895298	0.00822341	1.690366e-27	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01356198	chr3:187929513	3	187929513	LPP	Open sea	-0.02754	0.00216	2.4e-27	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg21779805	chr3:187982495	3	187982495	LPP	Open sea	1.64561	0.10396	2.4e-27	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0887852	0.00822396	4.5482740000000004e-27	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0887669	0.00822398	4.6600820000000004e-27	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0886258	0.00822408	5.616236e-27	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.0884568	0.00822421	7.020000000000001e-27	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0884417	0.00822422	7.160762e-27	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0881968	0.0082244	9.885919e-27	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02904838	chr3:187871519	3	187871519	LPP	Island	0.00012	None	1.4e-26	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26124569	chr3:187975150	3	187975150	LPP	Open sea	0.03547	0.00284	1.4e-26	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.0876429	0.0082248	2.043577e-26	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.08756	0.00822486	2.2773300000000001e-26	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0875483	0.00822487	2.3123409999999998e-26	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.0873905	0.00822498	2.8406589999999997e-26	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0873767	0.00822499	2.8923319999999997e-26	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-1.53876	0.10124	3.25e-26	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0870509	0.00822523	4.4181419999999997e-26	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0869983	0.00822527	4.730121e-26	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.363942	0.0345138	6.374595e-26	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0867415	0.00822545	6.596789e-26	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0862528	0.0082258	1.239039e-25	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0862385	0.00822581	1.2619760000000001e-25	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0862234	0.00822582	1.286694e-25	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0857328	0.00822617	2.413481e-25	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.085653	0.00822623	2.672511e-25	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0854546	0.00822637	3.442216e-25	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0850877	0.00822663	5.488995e-25	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	3.1	0.303	7.5e-25	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0847047	0.0082269	8.91368e-25	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0846118	0.00822696	1.002283e-24	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg16278897	chr3:188397356	3	188397356	LPP	Open sea	-	-	1.25e-24	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.084317	0.00822717	1.452878e-24	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0842889	0.00822719	1.505069e-24	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	-0.02792	0.00238	2.5e-24	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.083814	0.00822752	2.7295659999999998e-24	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0837758	0.00822755	2.862953e-24	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0835629	0.00822769	3.734188e-24	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0827636	0.00822824	1.0061970000000001e-23	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0827295	0.00822827	1.0494110000000001e-23	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0821695	0.00822865	2.089354e-23	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0819843	0.00822878	2.621103e-23	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.10867	0.0109713	4.678579e-23	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Marttila S	-	25888029	2015-03-14	Ageing	GO_0007568	-	Additional file 1	DNA methylation	Age group	Sex and cell counts	Beta values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	Variable dispersion beta regression model	143	1	58.5	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.9743927	0.0985	4.6899999999999994e-23	-	25888029_ageing
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0814019	0.00822917	5.328994e-23	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0813902	0.00822918	5.405105e-23	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.517932	0.0523964	5.572343e-23	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.466426	0.0473057	7.140730000000001e-23	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0811298	0.00822935	7.411378e-23	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0810454	0.00822941	8.207288000000001e-23	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0809379	0.00822948	9.345702000000001e-23	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0808334	0.00822955	1.0601460000000002e-22	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0808051	0.00822957	1.096964e-22	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.321977	0.0328495	1.269587e-22	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0804524	0.00822981	1.676438e-22	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0803371	0.00822988	1.9251870000000001e-22	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0802601	0.00822994	2.110963e-22	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0800536	0.00823007	2.702285e-22	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15048700	chr3:188037871	3	188037871	LPP	Open sea	0.0013	None	4.3e-22	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0796116	0.00823036	4.574307e-22	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0793951	0.00823051	5.913418e-22	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.079363	0.00823053	6.142633e-22	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0792953	0.00823057	6.654435000000001e-22	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0791853	0.00823065	7.578681e-22	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19756112	chr3:188200427	3	188200427	LPP	Open sea	0.03342	0.00307	8.100000000000001e-22	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.038	0.00392	8.300000000000001e-22	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0790146	0.00823076	9.270556e-22	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0789565	0.0082308	9.927327e-22	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.332589	0.0346863	1.012435e-21	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0789035	0.00823083	1.056675e-21	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0787624	0.00823092	1.247277e-21	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0784311	0.00823114	1.839563e-21	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0783314	0.0082312	2.067021e-21	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0782567	0.00823125	2.2553649999999998e-21	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0778136	0.00823154	3.77796e-21	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0777551	0.00823157	4.043544e-21	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0777041	0.00823161	4.289644e-21	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24123854	chr3:187973091	3	187973091	LPP	Open sea	-0.02732	0.00257	5e-21	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.077241	0.0082319	7.326569999999999e-21	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.101352	0.010832	9.393438e-21	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0767561	0.00823221	1.279024e-20	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.0766015	0.00823231	1.526597e-20	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0765729	0.00823233	1.577144e-20	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0763944	0.00823244	1.9336289999999998e-20	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0763386	0.00823248	2.060643e-20	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0761489	0.0082326	2.5569000000000002e-20	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.076093	0.00823263	2.724756e-20	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0760066	0.00823269	3.005165e-20	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0758756	0.00823277	3.486218e-20	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06645975	chr3:188020837	3	188020837	LPP	Open sea	0.0017	None	4.4e-20	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0791038	0.00862515	5.2856009999999995e-20	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0754817	0.00823302	5.439495e-20	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0753444	0.0082331	6.348778e-20	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0753159	0.00823312	6.555474e-20	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0750762	0.00823327	8.579308999999999e-20	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0748408	0.00823342	1.11635e-19	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.074762	0.00823346	1.219107e-19	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0746141	0.00823356	1.43762e-19	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0744897	0.00823363	1.651122e-19	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0743969	0.00823369	1.83037e-19	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0743057	0.00823375	2.0253979999999997e-19	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0742811	0.00823376	2.0813249999999997e-19	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0742192	0.0082338	2.229149e-19	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.074207	0.00823381	2.2594939999999996e-19	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17023114	chr3:188590442	3	188590442	LPP	Open sea	0.0016	None	2.3e-19	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.0741471	0.00823384	2.414405e-19	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0741045	0.00823387	2.5308989999999997e-19	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0739639	0.00823396	2.956358e-19	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.07378	0.00823407	3.6212139999999996e-19	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0737236	0.0082341	3.8532449999999996e-19	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0734877	0.00823425	4.993682999999999e-19	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0733287	0.00823434	5.944321999999999e-19	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.0732363	0.0082344	6.576301999999999e-19	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0730841	0.00823449	7.76592e-19	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0730417	0.00823452	8.133045e-19	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0729843	0.00823455	8.658241999999999e-19	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.072873	0.00823462	9.774194999999998e-19	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.072767	0.00823468	1.096839e-18	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.416203	0.0471872	1.248778e-18	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0726384	0.00823476	1.261193e-18	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.019	0.00179	1.4e-18	None	32795589_Kyung-WK_eosinophilia_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.340959	0.03872	1.4143350000000001e-18	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0723938	0.00823491	1.643502e-18	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0723628	0.00823493	1.699623e-18	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0722701	0.00823498	1.878505e-18	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg07196133	chr3:188439649	3	188439649	LPP	Open sea	-0.014	0.00127	2e-18	None	32795589_Kyung-WK_eosinophilia_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.201667	0.0230331	2.21626e-18	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0717636	0.00823528	3.238815e-18	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0947095	0.0108718	3.316006e-18	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.071622	0.00823537	3.769242e-18	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.284547	0.0327684	4.172266e-18	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0715117	0.00823543	4.2405e-18	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0714296	0.00823548	4.629169e-18	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.0713997	0.0082355	4.779197e-18	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.071381	0.00823551	4.875184e-18	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-1.50874	0.13785	4.89e-18	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0713302	0.00823554	5.146417e-18	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0713163	0.00823555	5.223315e-18	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0712867	0.00823557	5.390785e-18	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0712414	0.00823559	5.656597e-18	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0712071	0.00823561	5.866815e-18	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0711214	0.00823566	6.4265630000000005e-18	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.0710586	0.0082357	6.869688e-18	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	3	0.345	8e-18	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0708845	0.0082358	8.262366e-18	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0708673	0.00823581	8.414439e-18	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0708044	0.00823585	8.993197e-18	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0706717	0.00823593	1.0347220000000001e-17	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17809494	chr3:188572244	3	188572244	LPP	Open sea	0.0023	None	1.1e-17	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0705355	0.00823601	1.1945710000000001e-17	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0828081	0.0097054	1.57553e-17	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0702124	0.00823619	1.67768e-17	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0701614	0.00823622	1.769856e-17	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.070105	0.00823626	1.87751e-17	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0700977	0.00823626	1.8920640000000003e-17	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0937848	0.01102	1.89967e-17	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0699875	0.00823633	2.1232140000000002e-17	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0699218	0.00823636	2.274092e-17	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0698872	0.00823638	2.3577090000000002e-17	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0698387	0.00823641	2.4803360000000003e-17	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0931177	0.0110017	2.827931e-17	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0697108	0.00823649	2.8340540000000003e-17	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0695556	0.00823657	3.330735e-17	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0694095	0.00823666	3.876071e-17	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg21101580	chr3:188545164	3	188545164	LPP	Open sea	0.015	0.00144	4.4e-17	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	-0.0692563	0.00823675	4.542899e-17	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0692062	0.00823678	4.7848040000000005e-17	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0691893	0.00823679	4.868983e-17	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.015	0.00151	5.2e-17	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0691044	0.00823683	5.3152e-17	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0690633	0.00823686	5.545605e-17	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.069	0.00823689	5.920036e-17	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0689407	0.00823693	6.293141000000001e-17	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.077218	0.00923846	6.928568e-17	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0688444	0.00823698	6.948591e-17	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0687756	0.00823702	7.458125e-17	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0769513	0.00922185	7.787228e-17	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0687198	0.00823705	7.898179e-17	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0686788	0.00823708	8.238118e-17	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0685777	0.00823713	9.138232000000001e-17	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.287915	0.0346027	9.39862e-17	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	-0.0684583	0.0082372	1.032618e-16	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0683655	0.00823725	1.135449e-16	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01356198	chr3:187929513	3	187929513	LPP	Open sea	0.00059	None	1.3e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0682289	0.00823733	1.30538e-16	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0021	None	1.4e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	2	0.238	1.4e-16	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0681358	0.00823738	1.435257e-16	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.0019	None	1.7e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0679513	0.00823749	1.731429e-16	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.01739	0.00211	1.8e-16	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0678361	0.00823755	1.946257e-16	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04423294	chr3:188479059	3	188479059	LPP	Open sea	0.0016	None	2e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0887544	0.01079	2.104069e-16	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0677298	0.00823761	2.167653e-16	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17317338	chr3:187985688	3	187985688	LPP	Open sea	-0.00055	0.000066	2.2e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0677145	0.00823762	2.201296e-16	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0675325	0.00823772	2.646163e-16	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0671793	0.00823792	3.776238e-16	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12459603	chr3:187925112	3	187925112	LPP	Open sea	0.03604	0.00405	4e-16	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10666406	chr3:187872353	3	187872353	LPP	Island	0.00042	0.000051	4.4e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.066989	0.00823802	4.570653e-16	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0669791	0.00823803	4.616016e-16	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0668686	0.00823809	5.155845e-16	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0668541	0.0082381	5.231059e-16	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	0.0668409	0.00823811	5.300518e-16	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0723465	0.00891804	5.354878e-16	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0668269	0.00823811	5.375104e-16	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg05548945	chr3:188550738	3	188550738	LPP	Open sea	-0.43202	0.0533	5.39e-16	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0667811	0.00823814	5.626596e-16	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0667625	0.00823815	5.732381e-16	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0667525	0.00823816	5.789832e-16	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0018	None	5.8e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0666014	0.00823824	6.731108e-16	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0665811	0.00823825	6.868369e-16	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0890499	0.011024	7.104423e-16	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	3.4	0.423	7.3e-16	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.0664563	0.00823832	7.776651e-16	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0664386	0.00823833	7.91459e-16	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0697284	0.00866122	8.864836e-16	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0662815	0.00823841	9.249139e-16	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.28604	0.0355614	9.287251e-16	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	2.2	0.268	9.8e-16	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0661979	0.00823846	0.000000000000001004863	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.066125	0.0082385	0.000000000000001079955	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2657250 (gene symbol: LPP)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2657250 (gene symbol: LPP)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg23060272	chr3:187870863	3	187870863	LPP	North shore	None	None	0.0000000000000011	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2657250__gene_symbol__lpp__meta-analysis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.03415	0.00391	0.0000000000000012	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0875961	0.0109313	0.000000000000001200169	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.06595	0.0082386	0.000000000000001283797	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0658071	0.00823867	0.000000000000001477809	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0657805	0.00823869	0.000000000000001517083	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0657677	0.0082387	0.000000000000001536292	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.105749	0.0132532	0.000000000000001582066	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	2.5	0.315	0.0000000000000016	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0657149	0.00823872	0.000000000000001618135	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0657118	0.00823873	0.00000000000000162302	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.108987	0.0136852	0.000000000000001789414	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	0.0655521	0.00823881	0.000000000000001898531	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0655224	0.00823883	0.000000000000001954579	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.279362	0.0351687	0.000000000000002085611	None	39706196_Hannah-M.-Smith_bmi_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.05	0.00624	0.0000000000000022	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0653888	0.0082389	0.000000000000002227762	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0653806	0.00823891	0.000000000000002245675	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.281918	0.0355911	0.0000000000000024977	None	39706196_Hannah-M.-Smith_bmi_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14306812	chr3:187871538	3	187871538	LPP	Island	0.0002	0.000026	0.0000000000000027	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0651575	0.00823903	0.000000000000002792192	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.0012	0.00015	0.0000000000000029	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0650703	0.00823907	0.000000000000003039876	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.065043	0.00823909	0.000000000000003121684	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0648294	0.0082392	0.000000000000003841835	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0854637	0.0108645	0.00000000000000390624	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0647572	0.00823924	0.000000000000004120205	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0646897	0.00823928	0.000000000000004398648	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.064569	0.00823934	0.000000000000004943206	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.0645184	0.00823937	0.000000000000005190448	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0644999	0.00823938	0.000000000000005284266	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0644814	0.00823939	0.000000000000005379411	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0644734	0.00823939	0.000000000000005420924	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12459603	chr3:187925112	3	187925112	LPP	Open sea	0.0015	0.00019	0.0000000000000058	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17392043	chr3:188495102	3	188495102	LPP	Open sea	-0.0023	0.00029	0.0000000000000058	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0642382	0.00823952	0.000000000000006798847	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03427317	chr3:188590339	3	188590339	LPP	Open sea	0.0014	None	0.000000000000007	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14330078	chr3:187930521	3	187930521	LPP	Open sea	-0.00034	0.000044	0.0000000000000073	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0641189	0.00823958	0.000000000000007624776	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.064115	0.00823958	0.000000000000007652934	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0641012	0.00823959	0.000000000000007755374	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0640745	0.00823961	0.000000000000007956329	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0640365	0.00823963	0.000000000000008251764	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0640093	0.00823964	0.00000000000000846922	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg14466506	chr3:188390968	3	188390968	LPP	Open sea	-0.015	0.00169	0.0000000000000088	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0638648	0.00823972	0.000000000000009725072	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0638357	0.00823973	0.000000000000009999282	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.063822	0.00823974	0.00000000000001013075	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0638191	0.00823974	0.0000000000000101596	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0635191	0.0082399	0.00000000000001352198	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0634404	0.00823994	0.0000000000000145707	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0634044	0.00823996	0.00000000000001507853	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.105204	0.0136737	0.00000000000001517936	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.405933	0.0527948	0.00000000000001563748	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22480993	chr3:187943102	3	187943102	LPP	Open sea	-0.00057	0.000074	0.000000000000016	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0633344	0.00824	0.00000000000001611299	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0633296	0.00824	0.00000000000001618737	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.0632088	0.00824006	0.00000000000001814796	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0631904	0.00824007	0.00000000000001846694	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0745894	0.00972922	0.00000000000001877731	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0631528	0.00824009	0.00000000000001913572	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00136852	chr3:188350489	3	188350489	LPP	Open sea	0.0013	None	0.000000000000021	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.042	0.00471	0.000000000000023	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0629384	0.0082402	0.00000000000002342883	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0628225	0.00824026	0.00000000000002612878	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	-0.0627397	0.00824031	0.00000000000002824483	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0627139	0.00824032	0.00000000000002893624	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0024	0.00031	0.000000000000029	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0626133	0.00824037	0.00000000000003180014	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0626029	0.00824038	0.00000000000003211139	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0624697	0.00824045	0.00000000000003637893	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.062426	0.00824047	0.00000000000003789734	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0624209	0.00824047	0.00000000000003807618	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0623943	0.00824048	0.00000000000003903538	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0623837	0.00824049	0.00000000000003942422	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0622912	0.00824054	0.00000000000004297946	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0622185	0.00824057	0.00000000000004599353	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0695269	0.00920854	0.0000000000000459948	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0621975	0.00824059	0.00000000000004690457	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	0.04	0.00459	0.000000000000047	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0621869	0.00824059	0.00000000000004736575	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0621378	0.00824062	0.00000000000004958354	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0620572	0.00824066	0.00000000000005344112	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05548945	chr3:188550738	3	188550738	LPP	Open sea	0.00078	None	0.000000000000054	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0651216	0.00865603	0.000000000000056525	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0733213	0.0097465	0.00000000000005671111	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15087520	chr3:187871600	3	187871600	LPP	Island	0.00032	0.000042	0.000000000000057	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0619368	0.00824072	0.00000000000005976513	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.0618899	0.00824074	0.00000000000006242228	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0618406	0.00824077	0.00000000000006534092	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.0617865	0.0082408	0.00000000000006869721	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.061711	0.00824083	0.00000000000007366438	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0823934	0.0110255	0.00000000000008281244	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0614647	0.00824096	0.00000000000009245279	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0614493	0.00824097	0.00000000000009377363	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.0614394	0.00824097	0.00000000000009463409	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12298996	chr3:188272255	3	188272255	LPP	Open sea	0.0016	None	0.0000000000001	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0613705	0.00824101	0.0000000000001008255	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0613424	0.00824102	0.0000000000001034659	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0613407	0.00824102	0.0000000000001036251	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	-0.0011	0.00015	0.00000000000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	-0.061	0.00703	0.00000000000011	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0612727	0.00824106	0.0000000000001103057	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0724338	0.00974412	0.0000000000001115278	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0725534	0.00976172	0.0000000000001124998	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0612071	0.00824109	0.0000000000001171516	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0611853	0.0082411	0.0000000000001195157	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0679725	0.00916507	0.0000000000001268627	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0611115	0.00824114	0.0000000000001278716	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0610167	0.00824119	0.0000000000001394621	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.060923	0.00824123	0.0000000000001519303	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0608298	0.00824128	0.0000000000001654036	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg15381713	chr3:187912327	3	187912327	LPP	Open sea	-0.05	0.00591	0.00000000000017	None	32795589_Kyung-WK_eosinophilia_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	0.283728	0.0384865	0.00000000000017549	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0607221	0.00824134	0.0000000000001824428	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0788771	0.0107081	0.0000000000001850115	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.060652	0.00824137	0.0000000000001944531	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.060625	0.00824138	0.0000000000001992906	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0605566	0.00824142	0.0000000000002120671	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0605274	0.00824143	0.000000000000217756	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0605228	0.00824144	0.0000000000002186631	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0604813	0.00824146	0.000000000000227048	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0625036	0.00852137	0.0000000000002334573	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.064	0.00754	0.00000000000024	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0603912	0.0082415	0.0000000000002463571	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0603519	0.00824152	0.0000000000002552678	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0602766	0.00824156	0.000000000000273264	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.330684	0.0452368	0.0000000000002786376	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0602412	0.00824158	0.0000000000002821378	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0602334	0.00824158	0.0000000000002841201	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0602152	0.00824159	0.0000000000002888251	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18603679	chr3:188247767	3	188247767	LPP	Open sea	0.002	None	0.00000000000031	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0601181	0.00824164	0.0000000000003152759	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0600744	0.00824166	0.0000000000003279235	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.0600629	0.00824167	0.000000000000331335	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0600134	0.00824169	0.000000000000346438	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0599812	0.00824171	0.0000000000003565962	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0599547	0.00824172	0.0000000000003652158	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0599516	0.00824172	0.0000000000003662211	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0016	0.00022	0.00000000000038	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0598844	0.00824175	0.0000000000003890287	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0598026	0.00824179	0.0000000000004186338	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg03427317	chr3:188590339	3	188590339	LPP	Open sea	-0.01388	0.00178	0.00000000000042	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0597843	0.0082418	0.0000000000004255598	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0087	0.0012	0.00000000000044	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0596927	0.00824185	0.0000000000004619442	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.053	0.0073	0.00000000000047	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0596604	0.00824186	0.0000000000004754899	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0596148	0.00824189	0.0000000000004952812	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0596076	0.00824189	0.0000000000004984617	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	0.0595838	0.0082419	0.0000000000005091641	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0595498	0.00824192	0.0000000000005248773	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.238298	0.0330022	0.0000000000005388734	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0595017	0.00824194	0.0000000000005479287	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0593977	0.00824199	0.0000000000006011409	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.059384	0.008242	0.0000000000006085	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0593787	0.008242	0.0000000000006114047	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0592601	0.00824206	0.0000000000006794175	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2657250 (gene symbol: LPP)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2657250 (gene symbol: LPP)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg05685023	chr3:187870940	3	187870940	LPP	North shore	None	None	0.0000000000007	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2657250__gene_symbol__lpp__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0592066	0.00824209	0.0000000000007124943	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	0.236704	0.0329667	0.0000000000007249492	None	39706196_Hannah-M.-Smith_bmi_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.40557	0.0564875	0.000000000000726359	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0613701	0.00855434	0.0000000000007624839	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0694433	0.00968594	0.0000000000007887527	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0590918	0.00824214	0.000000000000788864	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.256259	0.0357758	0.000000000000821621	None	39706196_Hannah-M.-Smith_bmi_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06547766	chr3:187930704	3	187930704	LPP	Open sea	0.0018	None	0.00000000000083	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0781193	0.0109085	0.0000000000008371425	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0589829	0.0082422	0.0000000000008686893	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0589136	0.00824223	0.0000000000009236206	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0589105	0.00824223	0.0000000000009260735	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0588826	0.00824225	0.0000000000009492463	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0587929	0.00824229	0.000000000001027439	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0587471	0.00824231	0.000000000001069768	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg12459603	chr3:187925112	3	187925112	LPP	Open sea	-2.240037	0.3147	0.0000000000011	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.058701	0.00824233	0.000000000001114076	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0586938	0.00824234	0.000000000001121166	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0767942	0.0107896	0.000000000001150563	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0586177	0.00824237	0.000000000001198815	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0585443	0.00824241	0.00000000000127862	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.058525	0.00824242	0.000000000001300567	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0585166	0.00824242	0.000000000001310175	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0585051	0.00824243	0.000000000001323461	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.232555	0.0327914	0.000000000001373579	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg15381713	chr3:187912327	3	187912327	LPP	Open sea	-0.05	0.00624	0.0000000000015	None	32795589_Kyung-WK_atopy_discovery
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	2	0.281	0.0000000000017	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0582151	0.00824257	0.000000000001705912	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0581971	0.00824258	0.00000000000173292	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.226135	0.0320547	0.000000000001795848	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0581352	0.00824261	0.000000000001829185	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0581059	0.00824262	0.000000000001876458	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0580939	0.00824263	0.000000000001896329	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0580809	0.00824263	0.000000000001917933	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0580468	0.00824265	0.000000000001975754	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0580077	0.00824267	0.000000000002044073	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	-0.129369	0.0183977	0.00000000000211126	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.043	0.0054	0.0000000000022	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0579232	0.00824271	0.000000000002200011	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.01172	0.0017	0.00000000000221	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.057906	0.00824272	0.000000000002233079	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0578844	0.00824273	0.000000000002275351	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0657938	0.00937061	0.000000000002294753	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.01586	0.0023	0.00000000000242	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0578023	0.00824277	0.000000000002443424	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0578	0.00824277	0.000000000002448342	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0576706	0.00824283	0.000000000002738889	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	-0.0576547	0.00824284	0.000000000002776776	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0575291	0.0082429	0.000000000003095248	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.057526	0.0082429	0.000000000003103541	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0751459	0.0107711	0.000000000003153496	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0673579	0.00966044	0.000000000003245534	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02716749	chr3:187871801	3	187871801	LPP	Island	-0.000041	0.0000059	0.0000000000034	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.189669	0.0272424	0.000000000003468529	None	39706196_Hannah-M.-Smith_bmi_discovery
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2657250 (gene symbol: LPP)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2657250 (gene symbol: LPP)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg14091103	chr3:187870929	3	187870929	LPP	North shore	None	None	0.0000000000035	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2657250__gene_symbol__lpp__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0573649	0.00824298	0.000000000003565937	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0573471	0.00824298	0.000000000003621022	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0573133	0.008243	0.000000000003727926	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0573091	0.008243	0.000000000003741501	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0674605	0.00970358	0.000000000003750263	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0572902	0.00824301	0.000000000003802717	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0572186	0.00824304	0.000000000004043957	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	-0.0571842	0.00824306	0.00000000000416521	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.05709	0.00824311	0.000000000004515843	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01683373	chr3:187916442	3	187916442	LPP	Open sea	-0.00055	0.00008	0.0000000000047	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0569882	0.00824315	0.0000000000049271	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0569442	0.00824317	0.000000000005116001	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0569379	0.00824318	0.000000000005143916	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0569265	0.00824318	0.000000000005194018	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2657250 (gene symbol: LPP)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2657250 (gene symbol: LPP)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg00119073	chr3:187870713	3	187870713	LPP	North shore	None	None	0.0000000000054	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2657250__gene_symbol__lpp__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.076243	0.0110491	0.00000000000540003	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0568718	0.00824321	0.000000000005442754	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0568444	0.00824322	0.000000000005571528	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.337193	0.048947	0.000000000005814228	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0637897	0.00926102	0.000000000005889252	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	1.3	0.19	0.0000000000059	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg02716749	chr3:187871801	3	187871801	LPP	Island	0.0053	8e-04	0.00000000000606	-	23334450_rheumatoid_arthritis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg17392043	chr3:188495102	3	188495102	LPP	Open sea	0.02845	0.00388	0.0000000000061	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.0567346	0.00824327	0.000000000006118198	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0567315	0.00824327	0.000000000006134125	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0567125	0.00824328	0.000000000006234538	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.0566706	0.0082433	0.00000000000646084	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.110296	0.0160507	0.000000000006599459	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	0.0565365	0.00824337	0.000000000007240659	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0564951	0.00824338	0.000000000007499798	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0564701	0.0082434	0.000000000007660395	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0564415	0.00824341	0.000000000007848704	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	0.0564383	0.00824341	0.000000000007869889	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0564269	0.00824342	0.00000000000794607	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0564143	0.00824342	0.000000000008031525	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0667062	0.00975237	0.000000000008232549	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0563735	0.00824344	0.000000000008313994	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0563474	0.00824345	0.000000000008499321	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0562947	0.00824348	0.000000000008886934	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0939012	0.0137638	0.000000000009308589	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12314978	chr3:188324556	3	188324556	LPP	Open sea	0.0562301	0.00824351	0.000000000009386076	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0660375	0.00968512	0.000000000009562641	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0561924	0.00824353	0.00000000000968954	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0561865	0.00824353	0.000000000009737261	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.029	0.00379	0.0000000000098	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0561785	0.00824353	0.000000000009803311	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0561783	0.00824353	0.000000000009804837	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0561741	0.00824353	0.000000000009840047	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0561153	0.00824356	0.00000000001034068	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0593606	0.00872869	0.00000000001081864	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0560008	0.00824361	0.00000000001138648	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0559765	0.00824363	0.00000000001162162	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0559717	0.00824363	0.0000000000116692	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Li S	-	28811542	2017-08-15	Age	EFO_0000246	-	Table S1	DNA methylation	Age	Cell counts	M values	years	Illumina HumanMethylation450	Whole blood	-	1366	2	73	Missing	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0113	0.00169178	0.000000000012	-	28811542_age
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg12120178	chr3:188103284	3	188103284	LPP	Open sea	0.017	0.00223	0.000000000012	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0586566	0.00865207	0.00000000001252051	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0558822	0.00824367	0.00000000001258058	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0653652	0.00965223	0.00000000001318169	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.073705	0.0109034	0.0000000000143416	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0666945	0.00986901	0.00000000001452148	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0673142	0.00997654	0.0000000000156314	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0556117	0.00824379	0.00000000001577955	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	0.0555945	0.0082438	0.00000000001600716	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	0.0076	0.0011	0.000000000017	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.155488	0.0231067	0.00000000001760455	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0554735	0.00824386	0.00000000001770744	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0554346	0.00824388	0.00000000001829065	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.055418	0.00824388	0.00000000001854613	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0553777	0.0082439	0.00000000001917917	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0553767	0.0082439	0.00000000001919483	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.0552789	0.00824395	0.00000000002082081	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Dogan MV	-	28686328	2017-07-07	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	-	Table S1	DNA methylation	Smoking	Age, sex and technical covariates	M values	-	Illumina HumanMethylation450	Peripheral blood	-	1597	1	67	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.61057949	0.0912	0.0000000000218	-	28686328_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.055222	0.00824397	0.00000000002182787	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.053	0.00798	0.000000000022	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0552028	0.00824398	0.00000000002217784	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0551703	0.008244	0.00000000002278407	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0551226	0.00824402	0.00000000002370359	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.036	0.00473	0.000000000024	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	-0.0560537	0.00839201	0.00000000002485496	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0550243	0.00824406	0.00000000002571231	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	0.00094	None	0.000000000026	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0549831	0.00824408	0.00000000002660256	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.0548495	0.00824414	0.00000000002970426	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23493553	chr3:188055123	3	188055123	LPP	Open sea	-0.00064	0.000096	0.000000000031	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	0.0547708	0.00824418	0.00000000003169582	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.032	0.00433	0.000000000032	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.054743	0.00824419	0.00000000003242827	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	0.0547422	0.00824419	0.00000000003245001	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.117899	0.0177785	0.00000000003437449	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0546262	0.00824424	0.00000000003569883	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0546249	0.00824424	0.00000000003573531	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0643538	0.00971372	0.00000000003592505	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	0.0546056	0.00824425	0.00000000003630637	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0545868	0.00824426	0.00000000003686954	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	-0.0545723	0.00824427	0.00000000003731194	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0544857	0.00824431	0.00000000004005709	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0544527	0.00824432	0.00000000004115358	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0544499	0.00824432	0.0000000000412481	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0544434	0.00824433	0.00000000004146829	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0544356	0.00824433	0.0000000000417355	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	-0.0543775	0.00824436	0.00000000004376677	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0543744	0.00824436	0.00000000004387841	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg00869941	chr3:187929592	3	187929592	LPP	Open sea	-2.223842	0.3374	0.0000000000439	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	-0.0543558	0.00824437	0.00000000004455026	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.054351	0.00824437	0.00000000004472397	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0543442	0.00824437	0.00000000004497472	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.107873	0.0163661	0.00000000004509856	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0543383	0.00824437	0.00000000004519076	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0543379	0.00824437	0.00000000004520644	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0587131	0.00891231	0.00000000004614117	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	0.0542822	0.0082444	0.00000000004730977	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0542456	0.00824441	0.00000000004874592	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.10676	0.0162304	0.00000000004935751	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg14306812	chr3:187871538	3	187871538	LPP	Island	0.00718	0.0011	0.0000000000494	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	-0.054218	0.00824443	0.00000000004985349	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0725012	0.0110263	0.00000000005020131	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.05419	0.00824444	0.00000000005100418	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.0541706	0.00824445	0.00000000005181938	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0541619	0.00824445	0.00000000005218706	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15131848	chr3:187875197	3	187875197	LPP	South shelf	-0.0009	0.00014	0.000000000055	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.23412	0.0356929	0.0000000000555941	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0540701	0.00824449	0.00000000005623712	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0540551	0.0082445	0.00000000005692671	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.054037	0.00824451	0.00000000005776801	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0606392	0.00925887	0.00000000005972657	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0539707	0.00824454	0.00000000006096372	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.051	0.00693	0.000000000061	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.106038	0.0162006	0.00000000006133612	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0896805	0.0137161	0.00000000006426384	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0538771	0.00824458	0.00000000006577512	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.230413	0.03527	0.00000000006633358	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0538572	0.00824459	0.00000000006684332	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15213399	chr3:188415784	3	188415784	LPP	Open sea	-0.002	0.00031	0.000000000075	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0537049	0.00824466	0.00000000007560939	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0537027	0.00824466	0.00000000007573888	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	0.0536944	0.00824466	0.0000000000762489	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.053679	0.00824467	0.00000000007720484	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0536688	0.00824467	0.00000000007784326	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	0.0536577	0.00824468	0.00000000007854385	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0536052	0.0082447	0.00000000008194498	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0536004	0.0082447	0.00000000008225915	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.207626	0.031966	0.00000000008517176	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.0535437	0.00824473	0.00000000008610925	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.055632	0.00856685	0.00000000008634922	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0535203	0.00824474	0.00000000008774531	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0535168	0.00824474	0.00000000008799081	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg15131848	chr3:187875197	3	187875197	LPP	South shelf	-0.01118	0.0017	0.0000000000882	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0688053	0.010601	0.00000000008831392	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-	-	0.000000000089	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0535009	0.00824475	0.00000000008913	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.206924	0.0318931	0.00000000008930574	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.071441	0.0110212	0.00000000009333832	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.122492	0.0189151	0.00000000009681456	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0533731	0.0082448	0.00000000009877633	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0533684	0.0082448	0.00000000009914759	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21779805	chr3:187982495	3	187982495	LPP	Open sea	0.013	0.0021	0.0000000001	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.063018	0.00973755	0.0000000001000197	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0533365	0.00824482	0.0000000001017192	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0533327	0.00824482	0.000000000102032	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0645324	0.00998491	0.0000000001058919	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0532839	0.00824484	0.0000000001061014	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	-0.053269	0.00824485	0.0000000001073757	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.053263	0.00824485	0.0000000001078905	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0532305	0.00824487	0.0000000001107442	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0532164	0.00824487	0.000000000112002	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0531615	0.0082449	0.0000000001170333	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0627406	0.00973224	0.0000000001179028	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0531073	0.00824492	0.0000000001222091	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0530911	0.00824493	0.0000000001238063	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0530865	0.00824493	0.0000000001242585	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	1.9	0.288	0.00000000013	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0529241	0.008245	0.0000000001414523	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0528719	0.00824502	0.000000000147452	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0573263	0.00894001	0.0000000001476944	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0528569	0.00824503	0.0000000001492218	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0527553	0.00824507	0.0000000001617725	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.336662	0.0526306	0.0000000001628546	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	-0.0527465	0.00824508	0.000000000162911	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0527252	0.00824509	0.0000000001656917	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0527005	0.0082451	0.0000000001689688	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04103706	chr3:188514728	3	188514728	LPP	Open sea	0.0016	None	0.00000000017	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0526778	0.00824511	0.000000000172036	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09420838	chr3:187990766	3	187990766	LPP	Open sea	-0.0526753	0.00824511	0.0000000001723835	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0526645	0.00824511	0.0000000001738572	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0526491	0.00824512	0.0000000001759908	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0526434	0.00824512	0.0000000001767904	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.052992	0.00830461	0.0000000001811801	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.05258	0.00824515	0.0000000001858913	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0614749	0.00964399	0.0000000001891417	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0579627	0.00909344	0.0000000001895118	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0525199	0.00824518	0.0000000001949567	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0573479	0.00900443	0.0000000001961208	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14330078	chr3:187930521	3	187930521	LPP	Open sea	0.00035	None	0.0000000002	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16278897	chr3:188397356	3	188397356	LPP	Open sea	-0.0017	0.00027	0.0000000002	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2657250 (gene symbol: LPP)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2657250 (gene symbol: LPP)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg19599666	chr3:187871024	3	187871024	LPP	North shore	None	None	0.0000000002	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2657250__gene_symbol__lpp__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0970793	0.015258	0.0000000002043543	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.209153	0.0328934	0.0000000002088548	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0524025	0.00824523	0.0000000002138995	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.0524002	0.00824523	0.0000000002142914	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0523131	0.00824527	0.0000000002295167	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0523073	0.00824527	0.0000000002305669	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	0.0523023	0.00824527	0.0000000002314724	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.221055	0.0348596	0.0000000002332057	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg11020537	chr3:187871530	3	187871530	LPP	Island	0.00576	9e-04	0.000000000246	-	23334450_rheumatoid_arthritis
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.00110684	0.0001732	0.000000000247	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0522191	0.00824531	0.0000000002471467	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0522171	0.00824531	0.0000000002475333	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.287215	0.0453578	0.0000000002476292	None	39706196_Hannah-M.-Smith_body_fat_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.34629	0.0547093	0.0000000002514872	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0521218	0.00824535	0.0000000002667666	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09420838	chr3:187990766	3	187990766	LPP	Open sea	-0.0520814	0.00824537	0.0000000002753703	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0520806	0.00824537	0.0000000002755473	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0520729	0.00824537	0.0000000002771983	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0520662	0.00824537	0.0000000002786604	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0520579	0.00824538	0.0000000002804858	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15087520	chr3:187871600	3	187871600	LPP	Island	0.00662	0.001	0.0000000003	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg05842762	chr3:188590543	3	188590543	LPP	Open sea	-0.01123	0.0018	0.000000000306	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.0519319	0.00824543	0.0000000003095677	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	-0.052183	0.00830984	0.0000000003488837	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0693611	0.0110479	0.0000000003521945	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0517556	0.00824551	0.0000000003552783	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0517526	0.00824551	0.0000000003561047	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.0517136	0.00824552	0.0000000003671047	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0691778	0.0110319	0.0000000003695448	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.0516761	0.00824554	0.0000000003779706	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0516504	0.00824555	0.000000000385608	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0516499	0.00824555	0.0000000003857662	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.094446	0.0150783	0.0000000003864351	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0516382	0.00824556	0.0000000003893001	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0516106	0.00824557	0.0000000003977248	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.039	0.00619	0.0000000004	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0515752	0.00824558	0.0000000004088279	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17809494	chr3:188572244	3	188572244	LPP	Open sea	-0.0012	0.00019	0.00000000041	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.0515667	0.00824559	0.0000000004115556	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0515551	0.00824559	0.0000000004152587	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0515432	0.0082456	0.000000000419139	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0515363	0.0082456	0.000000000421375	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0515275	0.0082456	0.0000000004242528	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0514922	0.00824562	0.0000000004360577	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14932952	chr3:187943282	3	187943282	LPP	Open sea	-0.00063	0.0001	0.00000000044	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	-0.284446	0.0455686	0.0000000004416577	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0606161	0.00971011	0.0000000004422794	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0514562	0.00824563	0.0000000004483802	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.232267	0.0372278	0.0000000004504011	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0541165	0.00867346	0.0000000004515373	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.297754	0.0477314	0.000000000453149	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0602741	0.00966351	0.0000000004574469	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14932952	chr3:187943282	3	187943282	LPP	Open sea	-0.00928	0.00141	0.00000000046	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0514227	0.00824565	0.0000000004601884	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0514139	0.00824565	0.0000000004633506	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0514015	0.00824566	0.000000000467827	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0513976	0.00824566	0.0000000004692359	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05984281	chr3:188413418	3	188413418	LPP	Open sea	-0.0513574	0.00824568	0.0000000004840706	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0513417	0.00824568	0.0000000004899784	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.055805	0.00896411	0.0000000004934887	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0513157	0.00824569	0.0000000004999141	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0799657	0.0128637	0.0000000005225895	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0511942	0.00824574	0.0000000005491121	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Petersen A-K	KORA F4	24014485	2013-09-06	M00054_tryptophan	EFO_0004727, EFO_0004725	no snps model	Table S2	M00054_tryptophan	DNA methylation	Age, sex, body mass index, cell composition (reference based)	None	Beta Values	Illumina HumanMethylation450	Whole blood	None	1760	1	Adults	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.37	0.022	0.00000000055	None	24014485_Petersen-A-K_m00054_tryptophan_no_snps_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0511627	0.00824576	0.0000000005626333	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16915803	chr3:187909561	3	187909561	LPP	Open sea	0.001	None	0.00000000057	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	0.0011	None	0.00000000057	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.082285	0.0132681	0.000000000573564	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0510878	0.00824579	0.0000000005960688	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.068454	0.011049	0.000000000596473	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-1.7	0.277	0.0000000006	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0510396	0.00824581	0.0000000006186045	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.0510098	0.00824582	0.0000000006329157	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0509638	0.00824584	0.0000000006556835	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0509501	0.00824585	0.0000000006626212	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0509441	0.00824585	0.000000000665686	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.050908	0.00824587	0.0000000006843842	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.050907	0.00824587	0.0000000006849508	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0508229	0.0082459	0.0000000007305601	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03945529	chr3:188024721	3	188024721	LPP	Open sea	0.0508166	0.0082459	0.0000000007341091	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0534548	0.00867626	0.0000000007415468	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.1	0.0162	0.00000000075	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0507515	0.00824593	0.000000000771613	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0731667	0.0118921	0.0000000007823379	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.144848	0.0235536	0.0000000007931884	None	39706196_Hannah-M.-Smith_bmi_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0012	0.00019	0.0000000008	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0507011	0.00824595	0.0000000008019428	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.050696	0.00824595	0.0000000008050531	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0593883	0.00966852	0.0000000008335937	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0506447	0.00824598	0.0000000008372757	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.02718	0.0044	0.000000000871	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0813323	0.0132625	0.0000000008873162	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0505684	0.00824601	0.0000000008874428	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0505517	0.00824602	0.0000000008988264	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0505322	0.00824602	0.0000000009122908	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.050532	0.00824602	0.0000000009123995	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02904838	chr3:187871519	3	187871519	LPP	Island	0.00035	None	0.00000000092	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0504954	0.00824604	0.0000000009382026	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.0504679	0.00824605	0.0000000009580467	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0504574	0.00824605	0.0000000009657609	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.346525	0.0566398	0.000000000967694	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.050447	0.00824606	0.00000000097344	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06547766	chr3:187930704	3	187930704	LPP	Open sea	-0.0014	0.00023	0.000000001	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0604967	0.00989649	0.000000001002866	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0534338	0.00874223	0.000000001007879	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0778325	0.0127403	0.000000001026983	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0503589	0.0082461	0.000000001040851	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0603069	0.00988097	0.000000001064935	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0503241	0.00824611	0.000000001068669	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0503212	0.00824611	0.000000001071026	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0502787	0.00824613	0.000000001106188	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0597525	0.00980107	0.000000001111189	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.07907	0.013	0.00000000116	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0523214	0.00859759	0.000000001189551	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0501787	0.00824617	0.000000001193208	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0656322	0.0107871	0.000000001198917	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.262355	0.0431521	0.000000001228782	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.050125	0.00824619	0.0000000012427	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.0501194	0.00824619	0.000000001248003	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.059072	0.00972946	0.000000001298868	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0500658	0.00824622	0.000000001299567	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0500203	0.00824624	0.000000001345007	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0516061	0.00851868	0.000000001412058	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	0.0499515	0.00824626	0.000000001416611	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0499455	0.00824627	0.000000001422961	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0499166	0.00824628	0.000000001454327	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.049895	0.00824629	0.000000001478115	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0596345	0.0098625	0.00000000151535	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0656903	0.010867	0.0000000015312	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_4
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.01637	0.00258	0.0000000016	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0497595	0.00824634	0.000000001636733	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.049758	0.00824634	0.000000001638591	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0497206	0.00824636	0.00000000168515	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.199485	0.0331118	0.000000001729901	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0496708	0.00824638	0.000000001749316	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.049628	0.0082464	0.000000001806316	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0496279	0.0082464	0.000000001806391	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.155001	0.0257654	0.000000001825344	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0496063	0.00824641	0.000000001835864	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0495512	0.00824643	0.000000001913107	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0662335	0.0110234	0.000000001917804	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	0.0495353	0.00824644	0.000000001936047	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0495202	0.00824644	0.00000000195809	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Yang BZ	-	23332324	2013-02-01	Child abuse	-	-	Appendix B	DNA methylation	Child abuse	Sex, age and ethnicity	Beta values	-	Illumina HumanMethylation450	Saliva	-	192	1	10	Both	European,African,Admixed,Other	cg15338041	chr3:187942570	3	187942570	LPP	Open sea	-	-	0.000000002	-	23332324_child_abuse
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0494638	0.00824646	0.000000002042224	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	0.0494538	0.00824647	0.000000002057522	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0494123	0.00823993	0.000000002061054	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0494492	0.00824647	0.000000002064703	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0518824	0.00865239	0.000000002065917	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0494442	0.00824647	0.00000000207236	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0494392	0.00824647	0.000000002080064	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.202529	0.0337887	0.000000002085948	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	ACADSB protein levels (SeqId = 17403-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACADSB protein levels (SeqId = 17403-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.25	0.209	0.0000000021	None	Gadd-DA_acadsb_protein_levels__seqid___17403-14__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0494025	0.00824649	0.00000000213783	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.058351	0.00974695	0.000000002192879	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	1.3	0.213	0.0000000023	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0492724	0.00824654	0.000000002355315	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0578747	0.00968913	0.000000002380925	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.049257	0.00824655	0.000000002382509	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-3.2	0.536	0.0000000024	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.0492416	0.00824656	0.000000002409978	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	0.0492395	0.00824656	0.000000002413773	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.250481	0.0419868	0.000000002480856	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.00127037	0.00021124	0.00000000249	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	0.0491499	0.00824659	0.000000002579883	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.0507275	0.00851233	0.000000002591374	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg02904838	chr3:187871519	3	187871519	LPP	Island	0.00678	0.0011	0.00000000263	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0490936	0.00824662	0.000000002689801	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0490886	0.00824662	0.000000002699811	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0490529	0.00824663	0.00000000277225	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.049049	0.00824663	0.000000002780083	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Dugue PA	Melbourne Collaborative Cohort Study	31552803	2019-09-25	Smoking	EFO_0006527, EFO_0004318	Current vs never smoking	Supplementary table 1	DNA methylation	Smoking	Sex, country of birth, age, alcohol consumption, cell composition (reference based), batch effects	M Values	None	Illumina HumanMethylation450	Whole blood	None	1851	1	Adults	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.19	0.032	0.0000000028	None	31552803_Dugue-PA_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.0490186	0.00824665	0.000000002843431	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	0.195852	0.0329564	0.000000002856217	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	0.0490054	0.00824665	0.000000002871449	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0489864	0.00824666	0.000000002912104	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0489599	0.00824667	0.000000002969679	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0489368	0.00824668	0.000000003020805	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.0489071	0.00824669	0.000000003087901	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0488932	0.0082467	0.000000003119658	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0488503	0.00824671	0.000000003220021	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0785273	0.0132617	0.000000003264292	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.04883	0.00824672	0.000000003268541	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0488216	0.00824673	0.000000003288803	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.167987	0.028416	0.00000000344921	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	-0.0487539	0.00824675	0.00000000345722	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21101580	chr3:188545164	3	188545164	LPP	Open sea	0.0487053	0.00824677	0.000000003583003	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0623928	0.0105733	0.000000003693499	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.189727	0.0321575	0.000000003700983	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0486289	0.0082468	0.000000003789906	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01720795	chr3:187879604	3	187879604	LPP	Open sea	-0.00928	0.0015	0.0000000038	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0486244	0.00824681	0.000000003802456	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0486097	0.00824681	0.000000003843704	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.048544	0.00824684	0.000000004033565	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0485259	0.00824684	0.000000004087626	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.210996	0.035875	0.000000004142293	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05984281	chr3:188413418	3	188413418	LPP	Open sea	0.048495	0.00824686	0.000000004181344	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0484776	0.00824686	0.000000004234785	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0484776	0.00824686	0.000000004234822	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	-0.0484612	0.00824687	0.000000004286066	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0484612	0.00824687	0.000000004286093	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02711245	chr3:188013909	3	188013909	LPP	Open sea	0.02059	0.00335	0.0000000044	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0484064	0.00824689	0.000000004461365	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	0.0484027	0.00824689	0.000000004473537	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0483951	0.0082469	0.000000004498323	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0978772	0.01668	0.000000004508065	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0483798	0.0082469	0.000000004548986	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0569151	0.00970589	0.000000004616275	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.253127	0.0431889	0.000000004686502	None	39706196_Hannah-M.-Smith_bmi_discovery
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	1.3	0.214	0.0000000047	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0483208	0.00824693	0.000000004749326	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0534337	0.00912456	0.000000004841942	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.11685	0.02	0.00000000498	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.0482546	0.00824695	0.000000004984268	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0569604	0.00973532	0.000000004993357	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0482404	0.00824696	0.000000005036125	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0482239	0.00824697	0.000000005097092	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15048700	chr3:188037871	3	188037871	LPP	Open sea	0.0038	None	0.0000000051	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08825138	chr3:188157078	3	188157078	LPP	Open sea	-0.0481831	0.00824698	0.000000005250764	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0967516	0.0165706	0.00000000537063	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.022	0.00341	0.0000000054	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0481022	0.00824701	0.00000000556911	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.8	0.137	0.0000000057	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0480578	0.00824703	0.000000005751826	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0789923	0.0135609	0.000000005830656	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.097339	0.0167121	0.000000005849378	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	-0.0480174	0.00824705	0.000000005922893	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0626383	0.0107826	0.000000006408193	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0479083	0.00824709	0.000000006410734	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0479069	0.00824709	0.000000006417268	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.202946	0.0349436	0.000000006440448	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0479006	0.00824709	0.000000006446554	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0478833	0.0082471	0.00000000652773	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0478717	0.00824711	0.000000006582817	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.047867	0.00824711	0.00000000660521	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0478652	0.00824711	0.000000006613764	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	0.0478489	0.00824711	0.000000006692326	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.047848	0.00824711	0.000000006696296	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0478391	0.00824712	0.000000006739778	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0478315	0.00824712	0.000000006776908	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0478065	0.00824713	0.000000006900497	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0477804	0.00824714	0.000000007031959	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.133466	0.0230438	0.000000007082122	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	0.0477585	0.00824715	0.000000007144052	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0541392	0.0093498	0.000000007165052	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.062118	0.0107309	0.000000007237978	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0868969	0.0150124	0.000000007253177	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0563015	0.00974349	0.0000000076959	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0797989	0.0138138	0.000000007770992	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0476332	0.0082472	0.000000007819216	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.056283	0.0097489	0.000000007932099	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.185008	0.03207	0.000000008110179	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.0484496	0.00840019	0.0000000081989	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0475652	0.00824723	0.000000008211627	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0740606	0.0128429	0.000000008248098	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0475409	0.00824724	0.000000008356415	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0475316	0.00824724	0.000000008412207	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0475121	0.00824725	0.000000008530948	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0475041	0.00824725	0.000000008580653	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0636392	0.0110492	0.000000008599494	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0474974	0.00824725	0.000000008621542	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Christiansen C	GENOA, SHS	33593402	2021-02-16	Smoking	EFO_0004318, EFO_0006527	Current vs never smoking meta-analysis in trans-ethnic samples	Table S4	DNA methylation	Smoking	Sex, cell composition (reference based), body mass index, batch effects, relatedness	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	3425	2	Adults	Both	Admixed	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.257	0.045	0.0000000087	None	33593402_Christiansen-C_smoking_current_vs_never_smoking_meta-analysis_in_trans-ethnic_samples
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0474689	0.00824726	0.000000008799971	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.0474644	0.00824727	0.000000008828814	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.069614	0.0120961	0.000000008833971	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.0488169	0.00848509	0.000000008928626	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0621322	0.0107995	0.000000008930445	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0474396	0.00824728	0.00000000898702	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	0.0474364	0.00824728	0.000000009007548	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0474132	0.00824729	0.000000009158635	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00869941	chr3:187929592	3	187929592	LPP	Open sea	-0.00092	0.00016	0.0000000092	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	0.0473953	0.00824729	0.000000009277146	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0695904	0.0121193	0.00000000953509	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0072	0.0013	0.0000000096	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Christiansen C	TwinsUK, NSHD, NCDS1, NCDS2, BCS70	33593402	2021-02-16	Smoking	EFO_0004318, EFO_0006527	Current vs never smoking meta-analysis in European samples	Table S1	DNA methylation	Smoking	Sex, cell composition (reference based), body mass index, batch effects, relatedness	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	912	5	Adults	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	None	None	0.0000000096	None	33593402_Christiansen-C_smoking_current_vs_never_smoking_meta-analysis_in_european_samples
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0473345	0.00824732	0.000000009690133	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0568083	0.00989962	0.000000009744814	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0473227	0.00824732	0.00000000977228	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.0017	None	0.0000000099	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0472922	0.00824733	0.000000009987704	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0472787	0.00824734	0.00000001008483	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	0.222169	0.0387601	0.00000001009693	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0472669	0.00824734	0.00000001017049	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0472631	0.00824734	0.00000001019815	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.0472363	0.00824736	0.00000001039486	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0731549	0.0127767	0.00000001050503	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0556233	0.00972793	0.000000010995	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	-0.0471565	0.00824739	0.0000000110046	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0471478	0.00824739	0.00000001107309	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0471423	0.00824739	0.00000001111674	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0470918	0.00824741	0.00000001152402	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg27322975	chr3:188354136	3	188354136	LPP	Open sea	-1.659558	0.2909	0.0000000116	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0470693	0.00824742	0.00000001171028	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0470661	0.00824742	0.00000001173703	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0470659	0.00824742	0.00000001173849	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21101580	chr3:188545164	3	188545164	LPP	Open sea	-0.0470602	0.00824742	0.00000001178612	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.108148	0.0189636	0.00000001197004	None	39706196_Hannah-M.-Smith_body_fat_discovery
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	-0.057	0.00916	0.000000012	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	0.0470206	0.00824744	0.00000001212319	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0469921	0.00824745	0.0000000123717	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0575842	0.0101087	0.00000001246458	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0469631	0.00824746	0.00000001262922	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0469561	0.00824746	0.0000000126919	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.046952	0.00824747	0.0000000127294	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0469429	0.00824747	0.0000000128115	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0469409	0.00824747	0.00000001282953	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.046934	0.00824747	0.0000000128927	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0469338	0.00824747	0.00000001289457	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0468908	0.00824749	0.00000001329386	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.0468443	0.00824751	0.00000001373964	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0468078	0.00824752	0.00000001410052	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0468076	0.00824752	0.00000001410176	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0467451	0.00824755	0.00000001474046	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0467341	0.00824755	0.00000001485489	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0467213	0.00824756	0.00000001499034	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0467196	0.00824756	0.00000001500807	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0467158	0.00824756	0.0000000150483	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0467046	0.00824756	0.00000001516788	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0466792	0.00824757	0.00000001544345	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.046676	0.00824757	0.00000001547799	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.060471	0.0106888	0.00000001565405	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.046643	0.00824759	0.00000001584259	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.046642	0.00824759	0.00000001585384	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0559275	0.0098903	0.00000001589523	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0466252	0.00824759	0.00000001604346	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0570419	0.0100924	0.00000001615944	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.050502	0.00893638	0.0000000162222	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0466069	0.0082476	0.0000000162518	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0511397	0.00905034	0.00000001628757	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.149843	0.026522	0.00000001630766	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0465665	0.00824761	0.00000001672097	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0465615	0.00824762	0.00000001678021	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.046546	0.00824762	0.00000001696458	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0465437	0.00824762	0.00000001699217	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg21779805	chr3:187982495	3	187982495	LPP	Open sea	0.07986	0.0142	0.0000000173	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0465083	0.00824764	0.00000001742084	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0744467	0.0132089	0.00000001771536	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg15048700	chr3:188037871	3	188037871	LPP	Open sea	-0.02152	0.0038	0.0000000178	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.046202	0.00819874	0.00000001780236	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0464719	0.00824765	0.00000001787285	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0464497	0.00824766	0.00000001815382	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0464315	0.00824767	0.00000001838804	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0464291	0.00824767	0.00000001841945	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.07534	0.0134	0.0000000189	-	25650246_gestational_age
Cardenas A	Project Viva	31300640	Jul 12, 2019	fractional exhaled nitric oxide (FeNO)	EFO_0005536	None	Supplementary Data 2	DNA methylation	fractional exhaled nitric oxide (FeNO)	Age, Sex, Smoking, Cell composition (reference free), Batch effects, Ancestry (other), Body mass index, Education, sine and cosine of season at sample collection	Beta values	ppb	Illumina HumanMethylationEPIC	nasal epithelium	None	517	1	Children	Both	Other	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	4.95	0.866	0.000000019	SE manually calculated	31300640_Cardenas-A_fractional_exhaled_nitric_oxide__feno_
Battram T	GEO	25424692	2020-09-15	Smoking	EFO_0004318, EFO_0005671, EFO_0006527	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE50660. Never vs former smokers	None	DNA methylation	Smoking	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	442	1	Adults	Both	European	cg20203915	chr3:187871836	3	187871836	LPP	Island	0.0103	0.0018	0.000000019	None	25424692_Battram-T_smoking_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse50660__never_vs_former_smokers
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0463496	0.0082477	0.00000001947653	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.046295	0.00824772	0.00000002023654	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0462901	0.00824772	0.00000002030741	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0470077	0.00838404	0.00000002098032	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.046238	0.00824774	0.00000002106167	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0462053	0.00824775	0.00000002154994	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0545877	0.00974843	0.00000002186534	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	0.0649971	0.0116102	0.00000002203942	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	-0.0461609	0.00824777	0.00000002222868	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0507524	0.0090704	0.00000002240667	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.046144	0.00824778	0.00000002249292	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0500555	0.00894816	0.0000000225934	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0461327	0.00824778	0.00000002267132	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0461185	0.00824779	0.0000000228966	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03945529	chr3:188024721	3	188024721	LPP	Open sea	0.0461162	0.00824779	0.00000002293441	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0460938	0.0082478	0.00000002329492	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0773026	0.0138323	0.00000002330464	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.05935	0.0106267	0.0000000237906	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0460527	0.00824781	0.00000002397268	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0560134	0.010033	0.00000002407061	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0507663	0.00909442	0.00000002417993	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0460402	0.00824782	0.00000002418263	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0459988	0.00824783	0.00000002489173	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg01678383	chr3:187903164	3	187903164	LPP	Open sea	-0.01857	0.0033	0.0000000251	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0459651	0.00824784	0.00000002548163	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0459429	0.00824785	0.00000002588001	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0480589	0.00863182	0.00000002627367	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0458965	0.00824787	0.00000002672789	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0458879	0.00824787	0.00000002688911	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	0.183882	0.0330618	0.00000002710251	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0727351	0.0130823	0.00000002747677	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0601131	0.0108207	0.00000002818699	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0458142	0.0082479	0.0000000283008	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0506206	0.00911575	0.00000002855372	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.054827	0.00987434	0.00000002865534	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0457392	0.00824793	0.00000002981173	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0457166	0.00824794	0.00000003028309	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.047076	0.00850222	0.00000003131495	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0456378	0.00824797	0.00000003197953	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-	-	0.0000000322	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0750485	0.0135675	0.000000032295	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0456201	0.00824798	0.0000000323741	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0462317	0.00836069	0.0000000326358	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0455962	0.00824798	0.00000003291133	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0455907	0.00824799	0.00000003303882	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.283357	0.0513142	0.00000003400085	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	0.0455259	0.00824801	0.00000003454872	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0455143	0.00824802	0.00000003482602	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.0455048	0.00824802	0.00000003505596	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0583001	0.01057	0.00000003534415	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0608422	0.0110309	0.00000003534455	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0454597	0.00824804	0.00000003616322	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0477708	0.0086681	0.00000003626134	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00819081	chr3:188103477	3	188103477	LPP	Open sea	-0.0454339	0.00824805	0.00000003680984	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.045432	0.00824805	0.00000003685806	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0536286	0.00973625	0.00000003687507	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14306812	chr3:187871538	3	187871538	LPP	Island	0.00497	0.00087	0.000000037	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0501929	0.00911535	0.00000003723867	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0454071	0.00824806	0.00000003749571	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0453999	0.00824806	0.00000003768224	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0453911	0.00824806	0.00000003791201	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.047	0.00795	0.000000038	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0453735	0.00824807	0.00000003837394	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0453561	0.00824807	0.00000003883431	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0453551	0.00824807	0.00000003886304	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.045333	0.00824808	0.00000003945549	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0453284	0.00824808	0.00000003958194	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	-0.017	0.00279	0.00000004	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12314978	chr3:188324556	3	188324556	LPP	Open sea	0.0452888	0.0082481	0.00000004067247	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0728355	0.0132663	0.00000004079996	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.193232	0.0351986	0.00000004081124	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0728099	0.0132625	0.0000000408783	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0452805	0.0082481	0.00000004090415	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0452649	0.00824811	0.00000004134611	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0725887	0.0132323	0.00000004186328	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0452425	0.00824812	0.00000004198547	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.262422	0.0478529	0.00000004218247	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0452232	0.00824812	0.00000004254387	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0452204	0.00824813	0.00000004262713	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0452185	0.00824813	0.00000004268115	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0452154	0.00824813	0.00000004277389	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0091	0.0017	0.000000043	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0451642	0.00824815	0.00000004429962	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.045145	0.00824815	0.00000004488611	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Discovery and replication	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	979	1	48.3	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	12.81	2.32	0.000000045	-	27777315_postprandial_lipemia_discovery_and_replication
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0451344	0.00824816	0.00000004521314	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0451336	0.00824816	0.00000004523793	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0885813	0.0161891	0.00000004531663	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	0.0450659	0.00824818	0.00000004738238	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0450652	0.00824818	0.00000004740531	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0450643	0.00824818	0.00000004743384	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0450592	0.00824819	0.00000004759759	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14177865	chr3:188607928	3	188607928	LPP	Open sea	-0.0011	0.0002	0.000000048	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15338041	chr3:187942570	3	187942570	LPP	Open sea	0.0063	0.0011	0.000000048	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.045028	0.0082482	0.00000004862402	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0450244	0.0082482	0.00000004874477	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	1.4	0.265	0.000000049	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0450047	0.00824821	0.00000004940442	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0449867	0.00824821	0.0000000500128	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0533363	0.00978521	0.0000000509828	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0449583	0.00824822	0.00000005099194	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	CD19+ B cells	Table S6	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	CD19+ B cells	-	71	1	-	Both	European	cg02579706	chr3:187960622	3	187960622	LPP	Open sea	-	-	0.000000051	-	26857698_primary_sjogrens_syndrome_cd19_b_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0507039	0.00930777	0.00000005191255	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-1.9	0.345	0.000000052	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.039	0.00708	0.000000052	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0449273	0.00824823	0.00000005208213	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.206937	0.0380352	0.0000000538043	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	0.0448648	0.00824826	0.00000005434651	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.04877	0.00896693	0.00000005447582	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0448601	0.00824826	0.0000000545188	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0448429	0.00824827	0.00000005516242	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0448381	0.00824827	0.00000005534092	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.044834	0.00824827	0.00000005549671	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg11020410	chr3:188277035	3	188277035	LPP	Open sea	0.022	0.00378	0.000000057	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0753707	0.0138821	0.0000000574671	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.2156	0.0397422	0.00000005874204	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0447384	0.0082483	0.00000005921992	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0447317	0.00824831	0.00000005948959	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.044725	0.00824831	0.00000005975853	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.024	0.00445	0.00000006	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0447094	0.00824832	0.00000006039458	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08825138	chr3:188157078	3	188157078	LPP	Open sea	-0.0447004	0.00824832	0.00000006076688	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0480888	0.008876	0.00000006127059	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0446859	0.00824832	0.00000006136455	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	0.0446731	0.00824833	0.00000006189938	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05707781	chr3:188464815	3	188464815	LPP	Open sea	0.0018	None	0.000000062	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0532477	0.00983314	0.0000000622077	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0446609	0.00824833	0.00000006241595	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.0446535	0.00824834	0.00000006272736	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0446429	0.00824834	0.00000006318197	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0446401	0.00824834	0.00000006330137	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.0446136	0.00824835	0.00000006444457	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-1.111733	0.2057	0.0000000653	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.0445919	0.00824836	0.00000006540064	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.034	0.0063	0.000000066	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0445571	0.00824837	0.00000006695521	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0445547	0.00824837	0.0000000670644	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	-0.251526	0.0466002	0.00000006840576	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15048700	chr3:188037871	3	188037871	LPP	Open sea	0.0071	0.0013	0.000000071	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	-0.045213	0.00838622	0.00000007101489	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg12297546	chr3:187938319	3	187938319	LPP	Open sea	-0.01233	0.0023	0.0000000717	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0444381	0.00824842	0.00000007255754	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.0444366	0.00824842	0.00000007263162	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0444094	0.00824843	0.00000007397592	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.0444049	0.00824843	0.00000007419898	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	-0.0444021	0.00824843	0.00000007434037	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.044393	0.00824843	0.0000000747986	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PRPS2 protein levels (SeqId = 18329-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRPS2 protein levels (SeqId = 18329-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribose-phosphate pyrophosphokinase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.13	0.209	0.000000075	None	Gadd-DA_prps2_protein_levels__seqid___18329-4__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.236477	0.04395	0.00000007521091	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0443639	0.00824844	0.00000007627685	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-1.9	0.359	0.000000077	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.161183	0.0299813	0.00000007709123	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0497709	0.0092582	0.00000007737723	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	0.0443376	0.00824845	0.00000007764195	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.045093	0.00839	0.00000007792278	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0068	0.0013	0.000000078	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0443086	0.00824846	0.00000007916898	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.162478	0.030255	0.00000007957669	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0519843	0.0096792	0.00000007961741	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.171204	0.0318804	0.00000007967454	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0442735	0.00824848	0.00000008106261	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0442659	0.00824848	0.00000008147703	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0442427	0.00824849	0.00000008275607	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0897052	0.0167256	0.00000008294067	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0746615	0.013932	0.00000008495952	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.044203	0.0082485	0.00000008498979	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0881467	0.0164531	0.00000008568005	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-	-	0.0000000859	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.044169	0.00824851	0.00000008694854	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.00026517	4.92e-05	0.0000000881	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0441287	0.00824853	0.00000008932866	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.18649	0.0348648	0.00000008952648	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0815831	0.0152535	0.00000009003382	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0441139	0.00824853	0.00000009022231	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0748667	0.0140033	0.00000009107834	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0440984	0.00824854	0.00000009116208	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0440817	0.00824855	0.00000009218677	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0440577	0.00824855	0.00000009367584	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0740766	0.013872	0.00000009432998	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0440445	0.00824856	0.0000000945085	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg04952622	chr3:188067331	3	188067331	LPP	Open sea	-0.02618	0.0049	0.0000000966	-	23334450_rheumatoid_arthritis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15423781	chr3:188027117	3	188027117	LPP	Open sea	-0.00043	0.00008	0.000000097	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.0439776	0.00824858	0.00000009883089	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0439747	0.00824858	0.00000009902261	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0439706	0.00824859	0.00000009929269	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0527954	0.00990447	0.00000009941192	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0439579	0.00824859	0.0000001001401	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0439552	0.00824859	0.0000001003176	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0439538	0.00824859	0.0000001004123	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0439308	0.0082486	0.000000101968	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0439292	0.0082486	0.0000001020727	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.043923	0.0082486	0.0000001024994	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	-0.0439032	0.00824861	0.0000001038577	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.043882	0.00824862	0.0000001053354	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0438621	0.00824863	0.0000001067416	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0438607	0.00824863	0.0000001068397	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0438536	0.00824863	0.0000001073485	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.0517026	0.00972777	0.0000001082533	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0481931	0.009068	0.0000001084348	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.145161	0.0273207	0.0000001090451	None	39706196_Hannah-M.-Smith_body_fat_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13282252	chr3:188581493	3	188581493	LPP	Open sea	0.00064	None	0.00000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-2.1	0.388	0.00000011	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	0.0437852	0.00824865	0.0000001123476	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0437566	0.00824866	0.0000001145032	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0497249	0.00937452	0.0000001147713	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0437521	0.00824867	0.0000001148512	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0437492	0.00824867	0.0000001150687	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0437151	0.00824868	0.0000001177053	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0502968	0.00949218	0.0000001182761	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0437076	0.00824868	0.0000001182909	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	-0.0437052	0.00824868	0.0000001184814	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg12459603	chr3:187925112	3	187925112	LPP	Open sea	-	-	0.000000119	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0516889	0.00975772	0.0000001192727	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P23142	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P23142	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0460189	0.00868798	0.0000001195241	P23142	41361833_Josephine_Robertson_P23142_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.082	0.01545	0.00000012	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12314978	chr3:188324556	3	188324556	LPP	Open sea	0.0436838	0.00824869	0.0000001201762	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0523532	0.00988726	0.0000001207251	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	0.0436743	0.00824869	0.0000001209354	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0436604	0.0082487	0.0000001220528	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0462135	0.0087319	0.0000001223999	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0436543	0.0082487	0.0000001225466	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0436496	0.0082487	0.0000001229311	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.044809	0.00847421	0.0000001256453	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0436126	0.00824872	0.0000001259877	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.043586	0.00824873	0.0000001282275	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0435848	0.00824873	0.0000001283253	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0435737	0.00824873	0.0000001292711	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.043572	0.00824873	0.0000001294181	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0435703	0.00824873	0.0000001295634	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0583076	0.0110417	0.0000001305461	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	-0.0435536	0.00824874	0.0000001310007	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0435504	0.00824874	0.0000001312825	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0435367	0.00824874	0.0000001324737	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0458285	0.00869241	0.000000136675	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.195903	0.0371611	0.0000001367802	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0434853	0.00824876	0.0000001370523	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0434747	0.00824877	0.0000001380182	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.035	0.00669	0.00000014	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0563734	0.0107027	0.0000001404593	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.0434348	0.00824878	0.0000001417048	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0434287	0.00824878	0.0000001422778	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0440884	0.00837493	0.000000142684	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.142218	0.027029	0.0000001443513	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0433904	0.0082488	0.000000145915	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0433893	0.0082488	0.0000001460217	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0433879	0.0082488	0.0000001461553	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0433803	0.0082488	0.0000001468851	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	0.0473813	0.00901184	0.0000001479433	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0433606	0.00824881	0.0000001488102	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.0433578	0.00824881	0.0000001490824	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0665193	0.0126609	0.0000001510004	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	-0.0433306	0.00824882	0.0000001517797	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0433202	0.00824882	0.0000001528246	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0433196	0.00824882	0.0000001528854	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0882117	0.0168021	0.0000001541789	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.043292	0.00824883	0.0000001556813	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0432745	0.00824884	0.0000001574852	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.043259	0.00824884	0.000000159102	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0577959	0.0110258	0.0000001611716	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.266365	0.0508227	0.0000001615366	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.236678	0.0451668	0.0000001623938	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0432276	0.00824885	0.0000001624184	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0468772	0.00894809	0.0000001638704	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	-0.239312	0.0456881	0.0000001642639	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0432056	0.00824886	0.0000001647762	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0919851	0.0175732	0.0000001678177	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.0431723	0.00824887	0.0000001684162	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0513152	0.00981187	0.0000001719204	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12314978	chr3:188324556	3	188324556	LPP	Open sea	0.0431288	0.00824889	0.0000001732948	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.043125	0.00824889	0.0000001737306	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-1.156407	0.2214	0.000000175	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0430988	0.0082489	0.0000001767421	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0430806	0.00824891	0.0000001788567	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0512901	0.00982094	0.0000001789127	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0513697	0.00983638	0.0000001790207	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0608691	0.0116563	0.0000001794216	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15087520	chr3:187871600	3	187871600	LPP	Island	0.0015	0.00028	0.00000018	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.269617	0.0516517	0.0000001810815	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	0.0430569	0.00824891	0.0000001816558	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	-0.206428	0.0395557	0.0000001822904	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0909783	0.0174333	0.0000001827047	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0543849	0.0104231	0.0000001836226	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.217504	0.0417014	0.0000001851749	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0430219	0.00824893	0.0000001858622	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.043161	0.00827799	0.0000001873801	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPPA protein levels (SeqId = 4148-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPPA protein levels (SeqId = 4148-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pappalysin-1	774	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	-1.01	0.193	0.00000019	None	Gadd-DA_pappa_protein_levels__seqid___4148-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.0435327	0.00835607	0.0000001916955	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0429578	0.00824895	0.0000001938102	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.221037	0.0424489	0.0000001939886	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.042921	0.00824896	0.0000001985223	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.133975	0.0257521	0.000000198892	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Qi, Y	Han Chinese hospital outpatients	34539625	Sep 3, 2020	Chronic Spontaneous Urticaria	EFO_0005531	None	None	DNA methylation	Chronic Spontaneous Urticaria	Age, Sex, Smoking, Batch effects	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	190	1	Adults	Both	East Asian	cg14407220	chr3:188548438	3	188548438	LPP	Open sea	-0.068	None	0.0000002	beta is mean methylation cases - mean methylation controls	34539625_Qi,-Y_chronic_spontaneous_urticaria
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0428973	0.00824897	0.0000002016234	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0470231	0.00904375	0.0000002025048	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	-0.04472	0.00860383	0.0000002044945	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0428698	0.00824898	0.0000002052654	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0616492	0.0118751	0.0000002114279	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.046796	0.00901595	0.0000002127015	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.0428139	0.008249	0.000000212878	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0460008	0.0088639	0.0000002134663	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0428044	0.008249	0.0000002142016	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0428029	0.008249	0.0000002144122	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0427769	0.00824901	0.0000002180757	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14177865	chr3:188607928	3	188607928	LPP	Open sea	0.0013	None	0.00000022	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	0.0427601	0.00824902	0.0000002204673	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0427534	0.00824902	0.0000002214204	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.0439666	0.00848334	0.000000221601	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0427481	0.00824902	0.0000002221921	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	-0.0427312	0.00824903	0.0000002246439	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0427291	0.00824903	0.0000002249566	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.0427263	0.00824903	0.0000002253597	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0427088	0.00824904	0.0000002279381	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0524551	0.0101395	0.0000002330046	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.042669	0.00824905	0.0000002339031	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0426688	0.00824905	0.0000002339428	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.197973	0.0382849	0.0000002353913	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.04264	0.00824906	0.0000002383425	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0426298	0.00824907	0.000000239931	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23493553	chr3:188055123	3	188055123	LPP	Open sea	0.00063	None	0.00000024	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0505014	0.00977433	0.0000002413502	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.0426136	0.00824907	0.0000002424625	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P23142	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P23142	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.042595	0.00824908	0.0000002454099	P23142	41361833_Josephine_Robertson_P23142_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0425917	0.00824908	0.0000002459325	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.042577	0.00824908	0.0000002482817	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0459351	0.00889988	0.0000002484212	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0425719	0.00824909	0.0000002491041	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	AKR1A1 protein levels (SeqId = 4192-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKR1A1 protein levels (SeqId = 4192-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aldo-keto reductase family 1 member A1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.08	0.209	0.00000025	None	Gadd-DA_akr1a1_protein_levels__seqid___4192-10__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0425639	0.00824909	0.0000002504027	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.0425377	0.0082491	0.0000002546837	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0425142	0.00824911	0.0000002585824	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0425081	0.00824911	0.0000002596083	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0425046	0.00824911	0.0000002601877	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0424977	0.00824911	0.0000002613479	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	-0.0424883	0.00824912	0.0000002629428	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	-0.0424869	0.00824912	0.0000002631813	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0424839	0.00824912	0.0000002636895	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.042481	0.00824912	0.0000002641955	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0424704	0.00824912	0.0000002660163	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0424671	0.00824912	0.000000266581	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0424665	0.00824912	0.0000002666742	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0424662	0.00824912	0.0000002667365	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0771309	0.0149852	0.0000002679217	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0424428	0.00824913	0.0000002707856	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0914395	0.0177727	0.0000002710607	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.045047	0.00875641	0.0000002717564	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0424299	0.00824914	0.0000002730659	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0489453	0.00951688	0.0000002738608	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.0424219	0.00824914	0.0000002744744	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0482707	0.00938688	0.0000002747969	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0424123	0.00824914	0.0000002761747	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0424095	0.00824914	0.0000002766725	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0904228	0.017594	0.0000002791223	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	2.3	0.438	0.00000028	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05548945	chr3:188550738	3	188550738	LPP	Open sea	0.0023	None	0.00000028	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.177326	0.0345163	0.0000002813688	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.042372	0.00824916	0.0000002834454	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.289999	0.0564845	0.000000286515	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0701252	0.0136652	0.0000002908673	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0423188	0.00824917	0.0000002933314	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0422958	0.00824918	0.0000002977101	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.011	0.0021	0.0000003	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.121019	0.0236154	0.000000301387	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0719105	0.0140391	0.0000003059224	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0422466	0.0082492	0.0000003072798	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0422255	0.00824921	0.0000003114868	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0422204	0.00824921	0.0000003124985	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0422155	0.00824921	0.0000003134927	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.0421919	0.00824922	0.0000003182891	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0421828	0.00824922	0.00000032015	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.0421801	0.00824922	0.0000003206968	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0553637	0.0108281	0.0000003211634	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0454035	0.0088819	0.0000003229231	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0421674	0.00824923	0.0000003233157	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0421636	0.00824923	0.0000003241105	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.0421634	0.00824923	0.0000003241637	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0599473	0.0117298	0.0000003250649	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0421511	0.00824923	0.0000003267261	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08825138	chr3:188157078	3	188157078	LPP	Open sea	0.0421488	0.00824923	0.0000003272165	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0548391	0.0107339	0.0000003279668	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	SNRPG protein levels (SeqId = 19276-124)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNRPG protein levels (SeqId = 19276-124)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Small nuclear ribonucleoprotein G	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.07	0.209	0.00000033	None	Gadd-DA_snrpg_protein_levels__seqid___19276-124__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0421297	0.00824924	0.0000003312408	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0497416	0.00974025	0.0000003317526	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0420948	0.00824925	0.000000338743	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0420935	0.00824925	0.0000003390142	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0420878	0.00824926	0.0000003402616	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0420777	0.00824926	0.0000003424676	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0496629	0.00973959	0.0000003455767	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.045942	0.00900988	0.0000003455837	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0420573	0.00824927	0.0000003469686	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PRG3 protein levels (SeqId = 9015-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRG3 protein levels (SeqId = 9015-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteoglycan 3	774	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.76	0.148	0.00000035	None	Gadd-DA_prg3_protein_levels__seqid___9015-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0420391	0.00824927	0.0000003510323	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0420339	0.00824927	0.0000003522114	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0420165	0.00824928	0.0000003561383	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.168287	0.033043	0.0000003562303	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Breast Cancer (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Breast Cancer (Self-report)	Age, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	8260	1	Adults (18-65y)	Females	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	-0.11	0.0216	0.00000036	None	Robert-F-Hillary_Prevalent_Breast_Cancer_(Self-report)_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.0431024	0.00847009	0.0000003648246	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.0419756	0.00824929	0.0000003655881	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-1.074046	0.2112	0.000000366	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.083646	0.0164453	0.0000003696178	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10666406	chr3:187872353	3	187872353	LPP	Island	0.0011	None	0.00000037	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0419547	0.0082493	0.0000003704959	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg01356198	chr3:187929513	3	187929513	LPP	Open sea	-1.456023	0.2865	0.000000373	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0520191	0.010233	0.0000003752003	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0444593	0.00874672	0.0000003761442	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0545645	0.0107367	0.0000003779395	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.24	0.0479	0.00000038	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	AP1G2 protein levels (SeqId = 12714-38)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AP1G2 protein levels (SeqId = 12714-38)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AP-1 complex subunit gamma-like 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.06	0.209	0.00000038	None	Gadd-DA_ap1g2_protein_levels__seqid___12714-38__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AGO3 protein levels (SeqId = 15323-112)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AGO3 protein levels (SeqId = 15323-112)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein argonaute-3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.06	0.209	0.00000038	None	Gadd-DA_ago3_protein_levels__seqid___15323-112__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0453654	0.00892961	0.0000003814033	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0694329	0.0136736	0.0000003863386	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.041888	0.00824932	0.0000003866106	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	UFC1 protein levels (SeqId = 3405-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UFC1 protein levels (SeqId = 3405-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-fold modifier-conjugating enzyme 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.06	0.209	0.00000039	None	Gadd-DA_ufc1_protein_levels__seqid___3405-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.041844	0.00824934	0.0000003976117	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0418378	0.00824934	0.0000003991828	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PYGL protein levels (SeqId = 11441-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PYGL protein levels (SeqId = 11441-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycogen phosphorylase, liver form	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.06	0.209	0.0000004	None	Gadd-DA_pygl_protein_levels__seqid___11441-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRPSAP2 protein levels (SeqId = 19150-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRPSAP2 protein levels (SeqId = 19150-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphoribosyl pyrophosphate synthase-associated protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.06	0.209	0.0000004	None	Gadd-DA_prpsap2_protein_levels__seqid___19150-20__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0672206	0.0132558	0.0000004004704	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0418312	0.00824934	0.0000004008727	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	0.0418283	0.00824935	0.0000004016074	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.0418023	0.00824935	0.0000004083024	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0418017	0.00824935	0.000000408476	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0417807	0.00824936	0.0000004139561	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0417702	0.00824937	0.0000004167286	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0439165	0.00867417	0.0000004179215	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	ST6GALNAC6 protein levels (SeqId = 7228-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ST6GALNAC6 protein levels (SeqId = 7228-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.06	0.209	0.00000042	None	Gadd-DA_st6galnac6_protein_levels__seqid___7228-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0417517	0.00824937	0.0000004216691	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0690868	0.0136505	0.000000421828	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0417307	0.00824938	0.0000004273393	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0548135	0.0108375	0.0000004293498	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0417117	0.00824939	0.0000004325349	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0416945	0.00824939	0.0000004372769	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17809494	chr3:188572244	3	188572244	LPP	Open sea	0.0047	None	0.00000044	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0416598	0.0082494	0.0000004470234	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0416542	0.00824941	0.0000004486117	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0416479	0.00824941	0.000000450415	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0416465	0.00824941	0.0000004508159	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0416338	0.00824941	0.0000004544526	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.075572	0.0149786	0.0000004581875	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.0416169	0.00824942	0.0000004593644	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg09342609	chr3:188008251	3	188008251	LPP	Open sea	-0.1689355	0.0335029	0.0000004597	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0459598	0.00911064	0.0000004598246	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.047	0.0094	0.00000046	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	MANF protein levels (SeqId = 9223-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MANF protein levels (SeqId = 9223-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mesencephalic astrocyte-derived neurotrophic factor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.05	0.209	0.00000046	None	Gadd-DA_manf_protein_levels__seqid___9223-11__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0415979	0.00824942	0.0000004649239	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.219252	0.0435202	0.000000475065	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.166516	0.0330693	0.0000004817437	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0665327	0.013213	0.0000004825484	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0415291	0.00824945	0.0000004856159	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0415279	0.00824945	0.0000004859963	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0702756	0.0139621	0.0000004878003	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	TKT protein levels (SeqId = 4306-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TKT protein levels (SeqId = 4306-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transketolase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.05	0.209	0.00000049	None	Gadd-DA_tkt_protein_levels__seqid___4306-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0415144	0.00824945	0.0000004901698	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00119073	chr3:187870713	3	187870713	LPP	North shore	-0.0431982	0.00858773	0.0000004956853	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0414906	0.00824946	0.0000004975789	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0414858	0.00824946	0.000000499091	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0414836	0.00824946	0.0000004997988	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0414788	0.00824947	0.0000005013293	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	0.269638	0.0536457	0.0000005050948	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.044913	0.00893819	0.0000005097658	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.00077	0.00015	0.00000051	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0414224	0.00824949	0.0000005194954	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0884744	0.017626	0.0000005239935	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0538405	0.01073	0.0000005288465	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0896004	0.017859	0.0000005307131	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.16082	0.0320684	0.0000005355288	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10339098	chr3:188313650	3	188313650	LPP	Open sea	0.00049	None	0.00000054	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	TPI1 protein levels (SeqId = 4309-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TPI1 protein levels (SeqId = 4309-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Triosephosphate isomerase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.05	0.209	0.00000054	None	Gadd-DA_tpi1_protein_levels__seqid___4309-59__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.044829	0.00894167	0.0000005407583	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0453407	0.00904449	0.0000005419083	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0413514	0.00824951	0.0000005433009	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0413425	0.00824951	0.0000005463305	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0413351	0.00824951	0.0000005488799	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10666406	chr3:187872353	3	187872353	LPP	Island	0.0017	0.00033	0.00000055	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0413268	0.00824952	0.0000005517619	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0413243	0.00824952	0.0000005526505	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0419294	0.00837535	0.0000005613327	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0581038	0.0116075	0.000000562967	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	GRB2 protein levels (SeqId = 5464-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRB2 protein levels (SeqId = 5464-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Growth factor receptor-bound protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.05	0.209	0.00000057	None	Gadd-DA_grb2_protein_levels__seqid___5464-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AKT1 protein levels (SeqId = 3392-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKT1 protein levels (SeqId = 3392-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RAC-gamma serine/threonine-protein kinase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.05	0.209	0.00000057	None	Gadd-DA_akt1_protein_levels__seqid___3392-68__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0412751	0.00824954	0.0000005700254	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24123854	chr3:187973091	3	187973091	LPP	Open sea	0.0412717	0.00824954	0.0000005712327	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0412565	0.00824954	0.0000005767459	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0412438	0.00824955	0.0000005813386	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0412368	0.00824955	0.0000005839003	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	1.180984	0.2364	0.000000586	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.0486199	0.00972836	0.0000005867053	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.0412208	0.00824955	0.0000005898353	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.075	0.0151	0.0000006	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0553463	0.0110851	0.000000601828	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0537245	0.0107635	0.0000006064852	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0411729	0.00824957	0.0000006078414	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.0493645	0.00989386	0.0000006125767	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0662793	0.0132843	0.0000006129974	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	ACYP2 protein levels (SeqId = 12812-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACYP2 protein levels (SeqId = 12812-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acylphosphatase-2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.04	0.209	0.00000062	None	Gadd-DA_acyp2_protein_levels__seqid___12812-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB5B protein levels (SeqId = 19222-124)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB5B protein levels (SeqId = 19222-124)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-5B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.04	0.209	0.00000063	None	Gadd-DA_rab5b_protein_levels__seqid___19222-124__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0442327	0.00887638	0.0000006325899	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.05341	0.0107207	0.0000006366213	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0410971	0.0082496	0.0000006374036	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0410664	0.00824961	0.000000649786	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TYK2 protein levels (SeqId = 5260-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TYK2 protein levels (SeqId = 5260-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Non-receptor tyrosine-protein kinase TYK2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.04	0.209	0.00000065	None	Gadd-DA_tyk2_protein_levels__seqid___5260-80__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.0410659	0.00824961	0.0000006500035	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0410635	0.00824961	0.0000006509653	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Reynolds LM	-	25404168	2014-11-18	Age	EFO_0000246	T cells	Additional file 1	DNA methylation	Age	Sex, ethnicity and technical covariates	M values	Years	Illumina HumanMethylation450	T cells	-	227	1	-	Missing	None	cg07196133	chr3:188439649	3	188439649	LPP	Open sea	-	-	0.000000658	-	25404168_age_t_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0489656	0.00984172	0.0000006588346	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	TOR1AIP1 protein levels (SeqId = 9039-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TOR1AIP1 protein levels (SeqId = 9039-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Torsin-1A-interacting protein 1	774	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.76	0.152	0.00000066	None	Gadd-DA_tor1aip1_protein_levels__seqid___9039-47__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.144798	0.0291131	0.0000006630153	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	0.0410176	0.00824962	0.0000006699312	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PIN1 protein levels (SeqId = 15474-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIN1 protein levels (SeqId = 15474-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.04	0.209	0.00000067	None	Gadd-DA_pin1_protein_levels__seqid___15474-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0440567	0.00886242	0.0000006729556	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0532086	0.0107035	0.0000006731786	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0444944	0.00895094	0.0000006738966	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0410076	0.00824963	0.0000006741621	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0410049	0.00824963	0.0000006752724	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05984281	chr3:188413418	3	188413418	LPP	Open sea	0.0409767	0.00824964	0.0000006873028	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRC59 protein levels (SeqId = 19163-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRC59 protein levels (SeqId = 19163-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leucine-rich repeat-containing protein 59	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.04	0.209	0.00000069	None	Gadd-DA_lrrc59_protein_levels__seqid___19163-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LDLRAP1 protein levels (SeqId = 18183-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LDLRAP1 protein levels (SeqId = 18183-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Low density lipoprotein receptor adapter protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.04	0.209	0.00000069	None	Gadd-DA_ldlrap1_protein_levels__seqid___18183-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0409677	0.00824964	0.0000006911497	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MLEC protein levels (SeqId = 6285-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MLEC protein levels (SeqId = 6285-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Malectin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.04	0.209	0.0000007	None	Gadd-DA_mlec_protein_levels__seqid___6285-71__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0487465	0.00982345	0.0000007045921	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0409361	0.00824965	0.0000007049359	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0528097	0.0106429	0.0000007056855	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.040928	0.00824965	0.0000007085212	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0409118	0.00824966	0.0000007157242	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0442938	0.0089348	0.0000007222529	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0532977	0.0107518	0.0000007236094	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.0408873	0.00824967	0.0000007267327	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CRKL protein levels (SeqId = 9877-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRKL protein levels (SeqId = 9877-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Crk-like protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.04	0.209	0.00000073	None	Gadd-DA_crkl_protein_levels__seqid___9877-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0539946	0.0109002	0.000000736804	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0408405	0.00824968	0.000000748245	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0429397	0.00867374	0.000000748306	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Battram T	GEO	27886173	2020-09-15	Crohn's disease	EFO_0000384	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Crohn's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	161	1	Adults	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.0251	0.00485	0.00000075	None	27886173_Battram-T_crohn_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Gadd DA	Generation Scotland	35945220	31/07/2022	ENAH protein levels (SeqId = 9757-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ENAH protein levels (SeqId = 9757-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein enabled homolog	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.04	0.209	0.00000075	None	Gadd-DA_enah_protein_levels__seqid___9757-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0408352	0.00824968	0.0000007507075	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0544465	0.0110015	0.0000007542021	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.253111	0.0511566	0.0000007577359	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0408114	0.00824969	0.0000007619158	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00119073	chr3:187870713	3	187870713	LPP	North shore	-0.0423635	0.00856942	0.0000007755282	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0407784	0.0082497	0.0000007777556	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0588571	0.0119074	0.0000007781833	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	SNX4 protein levels (SeqId = 3903-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNX4 protein levels (SeqId = 3903-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sorting nexin-4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000078	None	Gadd-DA_snx4_protein_levels__seqid___3903-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CRK protein levels (SeqId = 4976-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRK protein levels (SeqId = 4976-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adapter molecule crk	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000078	None	Gadd-DA_crk_protein_levels__seqid___4976-57__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0407596	0.00824971	0.0000007868918	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	APBB3 protein levels (SeqId = 13589-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APBB3 protein levels (SeqId = 13589-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Amyloid-beta A4 precursor protein-binding family B member 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000079	None	Gadd-DA_apbb3_protein_levels__seqid___13589-10__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.04075	0.00824971	0.0000007916087	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.040748	0.00824971	0.0000007925643	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	-1	0.205	0.0000008	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0407272	0.00824972	0.0000008028655	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0486611	0.00985937	0.0000008081802	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0428172	0.00867607	0.0000008099111	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Stroke	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Stroke	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18023	1	Adults (18-65y)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.035	0.00706	0.00000081	None	Robert-F-Hillary_Incident_Stroke_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	DEF6 protein levels (SeqId = 14090-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DEF6 protein levels (SeqId = 14090-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Differentially expressed in FDCP 6 homolog	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000081	None	Gadd-DA_def6_protein_levels__seqid___14090-23__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0487733	0.00988424	0.000000812591	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0407052	0.00824973	0.0000008139187	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.152906	0.0309991	0.0000008185266	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.040695	0.00824973	0.0000008190832	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FUT8 protein levels (SeqId = 8244-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FUT8 protein levels (SeqId = 8244-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-(1,6)-fucosyltransferase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000082	None	Gadd-DA_fut8_protein_levels__seqid___8244-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0406726	0.00824837	0.0000008270894	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	TBL2 protein levels (SeqId = 11227-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TBL2 protein levels (SeqId = 11227-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transducin beta-like protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000083	None	Gadd-DA_tbl2_protein_levels__seqid___11227-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RHOA protein levels (SeqId = 9855-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RHOA protein levels (SeqId = 9855-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transforming protein RhoA	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000083	None	Gadd-DA_rhoa_protein_levels__seqid___9855-10__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0484292	0.0098231	0.0000008307241	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.180082	0.0365364	0.000000834802	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0489453	0.00993003	0.0000008354858	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0412736	0.00837389	0.0000008362301	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0690797	0.0140158	0.0000008368855	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0406478	0.00824975	0.0000008434733	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0406341	0.00824975	0.0000008506305	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0481093	0.00976882	0.0000008537199	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0647581	0.0131503	0.000000855083	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0406231	0.00824976	0.0000008564476	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0460656	0.00935639	0.0000008596154	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.0444444	0.00902804	0.000000861841	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0440636	0.00895238	0.0000008659783	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0405994	0.00824976	0.0000008691406	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.0405981	0.00824976	0.0000008698496	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPT protein levels (SeqId = 5854-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPT protein levels (SeqId = 5854-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Microtubule-associated protein tau	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000087	None	Gadd-DA_mapt_protein_levels__seqid___5854-60__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0680845	0.0138382	0.0000008746171	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0460574	0.00936325	0.000000879498	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	DYNLL2 protein levels (SeqId = 11493-169)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DYNLL2 protein levels (SeqId = 11493-169)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dynein light chain 2, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000088	None	Gadd-DA_dynll2_protein_levels__seqid___11493-169__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MESDC2 protein levels (SeqId = 15299-102)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MESDC2 protein levels (SeqId = 15299-102)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: LRP chaperone MESD	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000088	None	Gadd-DA_mesdc2_protein_levels__seqid___15299-102__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0455241	0.00925624	0.0000008828566	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0648239	0.0131822	0.0000008859385	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB11A protein levels (SeqId = 17744-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB11A protein levels (SeqId = 17744-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-11A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000089	None	Gadd-DA_rab11a_protein_levels__seqid___17744-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NIT2 protein levels (SeqId = 17808-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NIT2 protein levels (SeqId = 17808-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Omega-amidase NIT2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.0000009	None	Gadd-DA_nit2_protein_levels__seqid___17808-37__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0464253	0.00944835	0.0000009038979	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.0405353	0.00824979	0.0000009043136	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPRE1 protein levels (SeqId = 12469-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPRE1 protein levels (SeqId = 12469-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Microtubule-associated protein RP/EB family member 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000091	None	Gadd-DA_mapre1_protein_levels__seqid___12469-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.040524	0.00824979	0.0000009106293	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.043879	0.00893622	0.000000919426	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15131848	chr3:187875197	3	187875197	LPP	South shelf	0.203878	0.0415243	0.0000009197163	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0405076	0.00824979	0.0000009199226	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.00044	0.000088	0.00000092	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0405028	0.0082498	0.0000009226738	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0404953	0.0082498	0.0000009269278	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0404949	0.0082498	0.0000009271942	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0404917	0.0082498	0.0000009290203	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.036	0.0073	0.00000093	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	EPB41 protein levels (SeqId = 4706-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPB41 protein levels (SeqId = 4706-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein 4.1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000093	None	Gadd-DA_epb41_protein_levels__seqid___4706-17__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0404889	0.0082498	0.0000009306329	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0404805	0.0082498	0.0000009354481	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	0.0404753	0.00824981	0.0000009384794	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0808007	0.0164733	0.000000944562	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Cardenas A	Project Viva	31300640	Jul 12, 2019	fractional exhaled nitric oxide (FeNO)	EFO_0005536	None	Supplementary Data 2	DNA methylation	fractional exhaled nitric oxide (FeNO)	Age, Sex, Smoking, Cell composition (reference free), Batch effects, Ancestry (other), Body mass index, Education, sine and cosine of season at sample collection	Beta values	ppb	Illumina HumanMethylationEPIC	nasal epithelium	None	517	1	Children	Both	Other	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	2.74	0.552	0.00000095	SE manually calculated	31300640_Cardenas-A_fractional_exhaled_nitric_oxide__feno_
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPKAPK2 protein levels (SeqId = 3820-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPKAPK2 protein levels (SeqId = 3820-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAP kinase-activated protein kinase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000095	None	Gadd-DA_mapkapk2_protein_levels__seqid___3820-68__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0570707	0.0116408	0.0000009556615	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	RDX protein levels (SeqId = 18373-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RDX protein levels (SeqId = 18373-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Radixin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.03	0.209	0.00000096	None	Gadd-DA_rdx_protein_levels__seqid___18373-13__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0526571	0.0107436	0.0000009624612	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0482642	0.00984975	0.0000009683987	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0445414	0.00909079	0.0000009704608	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0525252	0.0107238	0.0000009785221	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0802171	0.0163803	0.0000009826918	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	-0.0464595	0.00948835	0.0000009860783	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	FEV protein levels (SeqId = 12740-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FEV protein levels (SeqId = 12740-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FEV	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.02	0.209	0.00000099	None	Gadd-DA_fev_protein_levels__seqid___12740-55__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0403844	0.00824984	0.0000009926477	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0437241	0.00893299	0.0000009951325	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	GGA1 protein levels (SeqId = 13594-158)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GGA1 protein levels (SeqId = 13594-158)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor-binding protein GGA1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.02	0.209	0.000001	None	Gadd-DA_gga1_protein_levels__seqid___13594-158__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP2R5A protein levels (SeqId = 13622-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP2R5A protein levels (SeqId = 13622-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.02	0.209	0.000001	None	Gadd-DA_ppp2r5a_protein_levels__seqid___13622-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0403695	0.00824984	0.000001001796	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0481526	0.00984111	0.000001003625	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.225092	0.0460074	0.00000100402	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0403613	0.00824984	0.000001006831	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0403563	0.00824985	0.000001009947	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0522819	0.010689	0.000001013011	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0452567	0.0092529	0.000001013447	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0510528	0.0104408	0.000001020342	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.0403355	0.00824985	0.000001022956	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02711245	chr3:188013909	3	188013909	LPP	Open sea	-0.0403284	0.00824985	0.000001027466	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0403244	0.00824986	0.000001030008	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.153595	0.0314308	0.000001034197	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0475983	0.00974567	0.000001050235	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.176778	0.0361993	0.000001051158	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03415955	chr3:188028183	3	188028183	LPP	Open sea	0.0402818	0.00824987	0.000001057374	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0402797	0.00824987	0.000001058741	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0402791	0.00824987	0.000001059071	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0402602	0.00824988	0.00000107151	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0402567	0.00824988	0.000001073798	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0402565	0.00824988	0.000001073952	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0810076	0.0166053	0.000001080681	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0426793	0.00875194	0.000001090889	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	-0.0402275	0.00824989	0.000001093249	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CNP protein levels (SeqId = 6609-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CNP protein levels (SeqId = 6609-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 2',3'-cyclic-nucleotide 3'-phosphodiesterase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.02	0.209	0.0000011	None	Gadd-DA_cnp_protein_levels__seqid___6609-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	POLM protein levels (SeqId = 12851-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	POLM protein levels (SeqId = 12851-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA-directed DNA/RNA polymerase mu	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.02	0.209	0.0000011	None	Gadd-DA_polm_protein_levels__seqid___12851-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB5A protein levels (SeqId = 17205-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB5A protein levels (SeqId = 17205-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-5A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.02	0.209	0.0000011	None	Gadd-DA_rab5a_protein_levels__seqid___17205-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GUK1 protein levels (SeqId = 17325-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GUK1 protein levels (SeqId = 17325-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Guanylate kinase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.02	0.209	0.0000011	None	Gadd-DA_guk1_protein_levels__seqid___17325-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PKN1 protein levels (SeqId = 12562-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PKN1 protein levels (SeqId = 12562-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase N1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.02	0.209	0.0000011	None	Gadd-DA_pkn1_protein_levels__seqid___12562-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0402173	0.00824989	0.000001100074	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0402117	0.00824989	0.000001103898	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0402018	0.0082499	0.000001110617	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	0.0409071	0.00839516	0.000001112305	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	0.0411919	0.00845364	0.000001112448	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0401806	0.0082499	0.000001125169	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0401775	0.0082499	0.00000112731	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0626008	0.0128555	0.000001130116	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.0401723	0.00824991	0.000001130901	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0401719	0.00824991	0.000001131146	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0441462	0.00907008	0.000001143448	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0401533	0.00824991	0.000001144174	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.042084	0.00864721	0.000001146184	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0623874	0.0128207	0.000001149773	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0564061	0.0115967	0.000001162466	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	0.0401229	0.00824992	0.000001165703	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0401177	0.00824992	0.000001169387	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0400995	0.00824993	0.000001182464	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0400927	0.00824993	0.000001187456	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0450024	0.00926145	0.000001191348	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.156212	0.0321523	0.000001193236	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.0405537	0.00834686	0.000001194683	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.012	0.0024	0.0000012	None	33450751_Mulder-RH_sex_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	CD109 protein levels (SeqId = 3290-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD109 protein levels (SeqId = 3290-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: CD109 antigen	774	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	0.86	0.178	0.0000012	None	Gadd-DA_cd109_protein_levels__seqid___3290-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDIA6 protein levels (SeqId = 5650-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDIA6 protein levels (SeqId = 5650-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein disulfide-isomerase A6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000012	None	Gadd-DA_pdia6_protein_levels__seqid___5650-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TBCB protein levels (SeqId = 17686-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TBCB protein levels (SeqId = 17686-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tubulin-folding cofactor B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000012	None	Gadd-DA_tbcb_protein_levels__seqid___17686-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPKAPK3 protein levels (SeqId = 3822-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPKAPK3 protein levels (SeqId = 3822-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAP kinase-activated protein kinase 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000012	None	Gadd-DA_mapkapk3_protein_levels__seqid___3822-54__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PKM2 protein levels (SeqId = 4240-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PKM2 protein levels (SeqId = 4240-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pyruvate kinase PKM	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.02	0.209	0.0000012	None	Gadd-DA_pkm2_protein_levels__seqid___4240-31__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0400703	0.00824994	0.000001203853	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	-0.0400568	0.00824994	0.000001213778	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0495144	0.0101982	0.000001214934	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0420623	0.00866575	0.000001223305	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0400376	0.00824995	0.000001228152	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	0.0400365	0.00824995	0.000001228979	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0400237	0.00824996	0.000001238641	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0400213	0.00824996	0.000001240423	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0532019	0.0109695	0.000001247375	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.048568	0.0100165	0.000001254849	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0479837	0.00990261	0.000001275429	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0399707	0.00824997	0.00000127942	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0399662	0.00824997	0.000001282889	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0481021	0.00993118	0.000001288493	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0399445	0.00824998	0.000001299997	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.82	0.17	0.0000013	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	FTL protein levels (SeqId = 15324-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FTL protein levels (SeqId = 15324-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ferritin light chain	774	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.83	0.172	0.0000013	None	Gadd-DA_ftl_protein_levels__seqid___15324-58__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AP2A2 protein levels (SeqId = 13621-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AP2A2 protein levels (SeqId = 13621-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AP-2 complex subunit alpha-2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000013	None	Gadd-DA_ap2a2_protein_levels__seqid___13621-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDCD5 protein levels (SeqId = 12517-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDCD5 protein levels (SeqId = 12517-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Programmed cell death protein 5	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000013	None	Gadd-DA_pdcd5_protein_levels__seqid___12517-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF4B protein levels (SeqId = 14675-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF4B protein levels (SeqId = 14675-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 4B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000013	None	Gadd-DA_eif4b_protein_levels__seqid___14675-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAC1 protein levels (SeqId = 2870-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAC1 protein levels (SeqId = 2870-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related C3 botulinum toxin substrate 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000013	None	Gadd-DA_rac1_protein_levels__seqid___2870-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BID protein levels (SeqId = 5798-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BID protein levels (SeqId = 5798-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BH3-interacting domain death agonist	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000013	None	Gadd-DA_bid_protein_levels__seqid___5798-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GAP43 protein levels (SeqId = 15325-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GAP43 protein levels (SeqId = 15325-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Neuromodulin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000013	None	Gadd-DA_gap43_protein_levels__seqid___15325-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VPS24 protein levels (SeqId = 12508-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VPS24 protein levels (SeqId = 12508-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Charged multivesicular body protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000013	None	Gadd-DA_vps24_protein_levels__seqid___12508-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.039942	0.00824998	0.000001302004	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05160	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05160	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0399353	0.00824998	0.000001307314	P05160	41361833_Josephine_Robertson_P05160_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.039926	0.00824999	0.000001314751	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.047179	0.00974904	0.000001315935	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0418734	0.00865465	0.000001323156	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0447212	0.00924344	0.000001323783	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	0.0399062	0.00824999	0.00000133073	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0399059	0.00824999	0.000001330947	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0398988	0.00825	0.000001336766	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0636491	0.0131641	0.000001344501	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0797263	0.0164963	0.000001358574	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0430818	0.00891583	0.00000136495	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0398635	0.00825001	0.000001365784	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0798416	0.0165277	0.000001373759	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0630225	0.0130503	0.000001384688	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0398277	0.00825002	0.000001395874	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00136852	chr3:188350489	3	188350489	LPP	Open sea	-0.00079	0.00016	0.0000014	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02521428	chr3:188083758	3	188083758	LPP	Open sea	0.015	0.0032	0.0000014	None	33450751_Mulder-RH_sex_discovery
Christiansen C	TwinsUK, NSHD, NCDS1, NCDS2, BCS70	33593402	2021-02-16	Smoking	EFO_0004318, EFO_0006527	Current vs never smoking meta-analysis in European samples	Table S1	DNA methylation	Smoking	Sex, cell composition (reference based), body mass index, batch effects, relatedness	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	912	5	Adults	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	None	None	0.0000014	None	33593402_Christiansen-C_smoking_current_vs_never_smoking_meta-analysis_in_european_samples
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMK protein levels (SeqId = 9545-156)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMK protein levels (SeqId = 9545-156)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme K	774	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.98	0.203	0.0000014	None	Gadd-DA_gzmk_protein_levels__seqid___9545-156__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AKT1 protein levels (SeqId = 15627-83)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKT1 protein levels (SeqId = 15627-83)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RAC-alpha serine/threonine-protein kinase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000014	None	Gadd-DA_akt1_protein_levels__seqid___15627-83__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NAPA protein levels (SeqId = 4292-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAPA protein levels (SeqId = 4292-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-soluble NSF attachment protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000014	None	Gadd-DA_napa_protein_levels__seqid___4292-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDIA5 protein levels (SeqId = 5593-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDIA5 protein levels (SeqId = 5593-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein disulfide-isomerase A5	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.208	0.0000014	None	Gadd-DA_pdia5_protein_levels__seqid___5593-11__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.039822	0.00825002	0.000001400775	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0398186	0.00825002	0.000001403661	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.039815	0.00825002	0.000001406703	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0398132	0.00825003	0.000001408286	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12120178	chr3:188103284	3	188103284	LPP	Open sea	0.0398127	0.00825003	0.000001408728	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0398085	0.00825003	0.000001412257	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.0397996	0.00825003	0.000001419953	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.039798	0.00825003	0.00000142138	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0399231	0.00827767	0.00000142847	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0397858	0.00825003	0.000001431886	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.039768	0.00825004	0.000001447513	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.039764	0.00825004	0.000001451021	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.039757	0.00825004	0.000001457242	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0785099	0.0162927	0.000001459199	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0397297	0.00825005	0.000001481571	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.039717	0.00825006	0.000001493056	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0520918	0.0108218	0.000001497202	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03427317	chr3:188590339	3	188590339	LPP	Open sea	0.0042	None	0.0000015	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.024	0.00503	0.0000015	None	Robert-F-Hillary_Incident_COPD_Basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12459603	chr3:187925112	3	187925112	LPP	Open sea	0.0013	None	0.0000015	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	1.5	0.318	0.0000015	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.053	0.01098	0.0000015	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	KPNA6 protein levels (SeqId = 13969-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KPNA6 protein levels (SeqId = 13969-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Importin subunit alpha-7	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000015	None	Gadd-DA_kpna6_protein_levels__seqid___13969-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DKK4 protein levels (SeqId = 3365-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DKK4 protein levels (SeqId = 3365-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dickkopf-related protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000015	None	Gadd-DA_dkk4_protein_levels__seqid___3365-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PANK3 protein levels (SeqId = 12658-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PANK3 protein levels (SeqId = 12658-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pantothenate kinase 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000015	None	Gadd-DA_pank3_protein_levels__seqid___12658-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	YWHAB protein levels (SeqId = 14156-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YWHAB protein levels (SeqId = 14156-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 14-3-3 protein beta/alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000015	None	Gadd-DA_ywhab_protein_levels__seqid___14156-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB11 protein levels (SeqId = 7110-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB11 protein levels (SeqId = 7110-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 11	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000015	None	Gadd-DA_dnajb11_protein_levels__seqid___7110-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADPRHL2 protein levels (SeqId = 17332-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADPRHL2 protein levels (SeqId = 17332-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribose glycohydrolase ARH3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000015	None	Gadd-DA_adprhl2_protein_levels__seqid___17332-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PA2G4 protein levels (SeqId = 4258-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PA2G4 protein levels (SeqId = 4258-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proliferation-associated protein 2G4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000015	None	Gadd-DA_pa2g4_protein_levels__seqid___4258-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PEBP1 protein levels (SeqId = 4276-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PEBP1 protein levels (SeqId = 4276-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylethanolamine-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1.01	0.209	0.0000015	None	Gadd-DA_pebp1_protein_levels__seqid___4276-10__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0397029	0.00825006	0.000001505889	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	-0.0398034	0.00828152	0.000001552838	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0437357	0.0090998	0.000001553244	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0467174	0.00972656	0.000001577882	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0435835	0.00907451	0.000001579694	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0396132	0.00825009	0.000001590003	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0396076	0.00825009	0.000001595389	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.00356	0.00074	0.0000016	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	DTYMK protein levels (SeqId = 19504-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DTYMK protein levels (SeqId = 19504-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thymidylate kinase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000016	None	Gadd-DA_dtymk_protein_levels__seqid___19504-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RALA protein levels (SeqId = 14332-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RALA protein levels (SeqId = 14332-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Ral-A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000016	None	Gadd-DA_rala_protein_levels__seqid___14332-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CAB39 protein levels (SeqId = 17757-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAB39 protein levels (SeqId = 17757-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium-binding protein 39	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000016	None	Gadd-DA_cab39_protein_levels__seqid___17757-86__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C11orf68 protein levels (SeqId = 8307-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C11orf68 protein levels (SeqId = 8307-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UPF0696 protein C11orf68	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000016	None	Gadd-DA_c11orf68_protein_levels__seqid___8307-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TOR1AIP1 protein levels (SeqId = 10606-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TOR1AIP1 protein levels (SeqId = 10606-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Torsin-1A-interacting protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000016	None	Gadd-DA_tor1aip1_protein_levels__seqid___10606-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DOK2 protein levels (SeqId = 19578-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DOK2 protein levels (SeqId = 19578-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Docking protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000016	None	Gadd-DA_dok2_protein_levels__seqid___19578-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NPLOC4 protein levels (SeqId = 12993-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NPLOC4 protein levels (SeqId = 12993-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear protein localization protein 4 homolog	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000016	None	Gadd-DA_nploc4_protein_levels__seqid___12993-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PGLS protein levels (SeqId = 17799-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGLS protein levels (SeqId = 17799-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 6-phosphogluconolactonase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000016	None	Gadd-DA_pgls_protein_levels__seqid___17799-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAMBP protein levels (SeqId = 19187-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAMBP protein levels (SeqId = 19187-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: STAM-binding protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000016	None	Gadd-DA_stambp_protein_levels__seqid___19187-21__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0395986	0.0082501	0.000001604147	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0395851	0.0082501	0.000001617261	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0395741	0.0082501	0.000001628063	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0395696	0.00825011	0.000001632474	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0527455	0.0110011	0.000001646354	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.0402766	0.00840314	0.000001658852	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0395145	0.00825012	0.000001687792	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0395129	0.00825012	0.000001689405	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14306812	chr3:187871538	3	187871538	LPP	Island	0.00016	None	0.0000017	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	FTH1 protein levels (SeqId = 5934-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FTH1 protein levels (SeqId = 5934-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ferritin heavy chain|Ferritin light chain	774	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.82	0.172	0.0000017	None	Gadd-DA_fth1_protein_levels__seqid___5934-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANGPT1 protein levels (SeqId = 2811-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANGPT1 protein levels (SeqId = 2811-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Angiopoietin-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000017	None	Gadd-DA_angpt1_protein_levels__seqid___2811-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APOA1BP protein levels (SeqId = 16621-77)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APOA1BP protein levels (SeqId = 16621-77)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NAD(P)H-hydrate epimerase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000017	None	Gadd-DA_apoa1bp_protein_levels__seqid___16621-77__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GP5 protein levels (SeqId = 7185-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GP5 protein levels (SeqId = 7185-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet glycoprotein V	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000017	None	Gadd-DA_gp5_protein_levels__seqid___7185-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AGO1 protein levels (SeqId = 15312-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AGO1 protein levels (SeqId = 15312-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein argonaute-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000017	None	Gadd-DA_ago1_protein_levels__seqid___15312-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AKR7A2 protein levels (SeqId = 4188-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKR7A2 protein levels (SeqId = 4188-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aflatoxin B1 aldehyde reductase member 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000017	None	Gadd-DA_akr7a2_protein_levels__seqid___4188-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IST1 protein levels (SeqId = 12434-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IST1 protein levels (SeqId = 12434-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: IST1 homolog	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000017	None	Gadd-DA_ist1_protein_levels__seqid___12434-25__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0394921	0.00825013	0.000001710784	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0394792	0.00825013	0.000001724104	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0603209	0.0126063	0.000001726713	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0791095	0.0165347	0.000001731276	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0463705	0.00969625	0.000001749705	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0780135	0.016314	0.000001752501	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0394377	0.00825015	0.000001767853	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.0400472	0.00838005	0.000001779891	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0515432	0.0107882	0.000001789934	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0805386	0.0168583	0.000001793114	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	-0.0412122	0.00862717	0.000001796337	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23260255	chr3:187871479	3	187871479	LPP	Island	0.00031	0.000066	0.0000018	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF4G2 protein levels (SeqId = 4230-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF4G2 protein levels (SeqId = 4230-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 4 gamma 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000018	None	Gadd-DA_eif4g2_protein_levels__seqid___4230-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBXN4 protein levels (SeqId = 9997-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBXN4 protein levels (SeqId = 9997-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UBX domain-containing protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000018	None	Gadd-DA_ubxn4_protein_levels__seqid___9997-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARL1 protein levels (SeqId = 12392-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARL1 protein levels (SeqId = 12392-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor-like protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.997	0.209	0.0000018	None	Gadd-DA_arl1_protein_levels__seqid___12392-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HARS protein levels (SeqId = 17450-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HARS protein levels (SeqId = 17450-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histidine--tRNA ligase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000018	None	Gadd-DA_hars_protein_levels__seqid___17450-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CBX1 protein levels (SeqId = 18817-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBX1 protein levels (SeqId = 18817-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chromobox protein homolog 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.207	0.0000018	None	Gadd-DA_cbx1_protein_levels__seqid___18817-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DPYSL3 protein levels (SeqId = 12707-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPYSL3 protein levels (SeqId = 12707-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dihydropyrimidinase-related protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000018	None	Gadd-DA_dpysl3_protein_levels__seqid___12707-26__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0393963	0.00825016	0.000001812515	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0393869	0.00825016	0.000001822756	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.0404791	0.00847995	0.000001827915	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0528119	0.011064	0.000001829854	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0393791	0.00825017	0.00000183138	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.0393646	0.00825017	0.000001847434	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0393623	0.00825017	0.000001849952	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.168293	0.0352867	0.000001863675	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	-0.042152	0.00883774	0.000001864207	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0393401	0.00825018	0.000001874826	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0393383	0.00825018	0.000001876849	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0414	0.00868308	0.000001879544	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0445238	0.00933934	0.000001884735	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0447837	0.00939461	0.000001888262	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	IL31RA protein levels (SeqId = 8273-84)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL31RA protein levels (SeqId = 8273-84)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-31 receptor subunit alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000019	None	Gadd-DA_il31ra_protein_levels__seqid___8273-84__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IDI1 protein levels (SeqId = 17712-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IDI1 protein levels (SeqId = 17712-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Isopentenyl-diphosphate Delta-isomerase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000019	None	Gadd-DA_idi1_protein_levels__seqid___17712-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPCS protein levels (SeqId = 17843-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPCS protein levels (SeqId = 17843-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphopantothenate--cysteine ligase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000019	None	Gadd-DA_ppcs_protein_levels__seqid___17843-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GDI2 protein levels (SeqId = 2647-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GDI2 protein levels (SeqId = 2647-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rab GDP dissociation inhibitor beta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000019	None	Gadd-DA_gdi2_protein_levels__seqid___2647-66__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KPNB1 protein levels (SeqId = 3887-90)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KPNB1 protein levels (SeqId = 3887-90)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Importin subunit beta-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000019	None	Gadd-DA_kpnb1_protein_levels__seqid___3887-90__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GGA3 protein levels (SeqId = 11683-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GGA3 protein levels (SeqId = 11683-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor-binding protein GGA3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.0000019	None	Gadd-DA_gga3_protein_levels__seqid___11683-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0479091	0.0100568	0.000001917681	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0502556	0.0105543	0.00000193894	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0392824	0.0082502	0.000001941049	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0392767	0.0082502	0.000001947641	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0392644	0.0082502	0.000001962103	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.216272	0.045466	0.000001982804	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0392432	0.00825021	0.000001987229	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0392808	0.00825829	0.000001988217	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0511832	0.0107608	0.000001989218	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0392353	0.00825021	0.000001996686	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PRG3 protein levels (SeqId = 9015-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRG3 protein levels (SeqId = 9015-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteoglycan 3	774	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	-0.92	0.194	0.000002	None	Gadd-DA_prg3_protein_levels__seqid___9015-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	G6PD protein levels (SeqId = 19297-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	G6PD protein levels (SeqId = 19297-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glucose-6-phosphate 1-dehydrogenase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.000002	None	Gadd-DA_g6pd_protein_levels__seqid___19297-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TRIP10 protein levels (SeqId = 17676-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TRIP10 protein levels (SeqId = 17676-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cdc42-interacting protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.000002	None	Gadd-DA_trip10_protein_levels__seqid___17676-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARRB1 protein levels (SeqId = 12643-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARRB1 protein levels (SeqId = 12643-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-arrestin-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.000002	None	Gadd-DA_arrb1_protein_levels__seqid___12643-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BOLA3 protein levels (SeqId = 5980-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BOLA3 protein levels (SeqId = 5980-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BolA-like protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.000002	None	Gadd-DA_bola3_protein_levels__seqid___5980-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSPE1 protein levels (SeqId = 17150-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSPE1 protein levels (SeqId = 17150-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 10 kDa heat shock protein, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.000002	None	Gadd-DA_hspe1_protein_levels__seqid___17150-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GPI protein levels (SeqId = 4272-46)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GPI protein levels (SeqId = 4272-46)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glucose-6-phosphate isomerase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.000002	None	Gadd-DA_gpi_protein_levels__seqid___4272-46__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SMAD1 protein levels (SeqId = 9838-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMAD1 protein levels (SeqId = 9838-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mothers against decapentaplegic homolog 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.000002	None	Gadd-DA_smad1_protein_levels__seqid___9838-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GNPNAT1 protein levels (SeqId = 13954-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GNPNAT1 protein levels (SeqId = 13954-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glucosamine 6-phosphate N-acetyltransferase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.000002	None	Gadd-DA_gnpnat1_protein_levels__seqid___13954-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKCI protein levels (SeqId = 3379-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKCI protein levels (SeqId = 3379-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein kinase C iota type	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.000002	None	Gadd-DA_prkci_protein_levels__seqid___3379-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLEK protein levels (SeqId = 7875-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLEK protein levels (SeqId = 7875-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pleckstrin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	1	0.209	0.000002	None	Gadd-DA_plek_protein_levels__seqid___7875-86__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0392244	0.00825022	0.000002009811	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	0.0392183	0.00825022	0.000002017127	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0392144	0.00825022	0.000002021951	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0392139	0.00825022	0.000002022459	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0391968	0.00825023	0.000002043337	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0391712	0.00825023	0.000002074918	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	0.0404417	0.00851988	0.000002086689	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0391556	0.00825024	0.000002094456	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0391542	0.00825024	0.000002096198	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDH1 protein levels (SeqId = 3853-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDH1 protein levels (SeqId = 3853-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Malate dehydrogenase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000021	None	Gadd-DA_mdh1_protein_levels__seqid___3853-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GABARAPL1 protein levels (SeqId = 12661-44)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GABARAPL1 protein levels (SeqId = 12661-44)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-aminobutyric acid receptor-associated protein-like 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.992	0.209	0.0000021	None	Gadd-DA_gabarapl1_protein_levels__seqid___12661-44__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TIRAP protein levels (SeqId = 9839-148)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TIRAP protein levels (SeqId = 9839-148)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Toll/interleukin-1 receptor domain-containing adapter protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000021	None	Gadd-DA_tirap_protein_levels__seqid___9839-148__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAR protein levels (SeqId = 10085-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAR protein levels (SeqId = 10085-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Steroidogenic acute regulatory protein, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000021	None	Gadd-DA_star_protein_levels__seqid___10085-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLIC4 protein levels (SeqId = 15314-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLIC4 protein levels (SeqId = 15314-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chloride intracellular channel protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000021	None	Gadd-DA_clic4_protein_levels__seqid___15314-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0391457	0.00825024	0.000002106914	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0445054	0.00938176	0.000002116986	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0465919	0.00982211	0.000002119593	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.0391195	0.00825025	0.000002140221	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.052375	0.0110473	0.000002147069	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	0.0390953	0.00825026	0.000002171367	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	-0.0392746	0.00828955	0.000002180302	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.039083	0.00825026	0.000002187351	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0444629	0.00938715	0.000002194043	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Lung Cancer	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Lung Cancer	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18364	1	Adults (18-65y)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.01	0.00211	0.0000022	None	Robert-F-Hillary_Incident_Lung_Cancer_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPPA protein levels (SeqId = 4148-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPPA protein levels (SeqId = 4148-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pappalysin-1	774	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-1.05	0.221	0.0000022	None	Gadd-DA_pappa_protein_levels__seqid___4148-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FER protein levels (SeqId = 4220-39)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FER protein levels (SeqId = 4220-39)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase Fer	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000022	None	Gadd-DA_fer_protein_levels__seqid___4220-39__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	OVCA2 protein levels (SeqId = 17697-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	OVCA2 protein levels (SeqId = 17697-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Esterase OVCA2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000022	None	Gadd-DA_ovca2_protein_levels__seqid___17697-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF1AY protein levels (SeqId = 19224-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF1AY protein levels (SeqId = 19224-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 1A, Y-chromosomal	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000022	None	Gadd-DA_eif1ay_protein_levels__seqid___19224-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARL5A protein levels (SeqId = 18414-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARL5A protein levels (SeqId = 18414-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor-like protein 5A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000022	None	Gadd-DA_arl5a_protein_levels__seqid___18414-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UFD1L protein levels (SeqId = 17411-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UFD1L protein levels (SeqId = 17411-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin recognition factor in ER-associated degradation protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000022	None	Gadd-DA_ufd1l_protein_levels__seqid___17411-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3GL3 protein levels (SeqId = 18318-98)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3GL3 protein levels (SeqId = 18318-98)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endophilin-A3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000022	None	Gadd-DA_sh3gl3_protein_levels__seqid___18318-98__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NDUFV2 protein levels (SeqId = 7748-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NDUFV2 protein levels (SeqId = 7748-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000022	None	Gadd-DA_ndufv2_protein_levels__seqid___7748-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAFAH1B2 protein levels (SeqId = 2642-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAFAH1B2 protein levels (SeqId = 2642-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet-activating factor acetylhydrolase IB subunit beta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000022	None	Gadd-DA_pafah1b2_protein_levels__seqid___2642-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK14 protein levels (SeqId = 5007-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK14 protein levels (SeqId = 5007-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 14	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000022	None	Gadd-DA_mapk14_protein_levels__seqid___5007-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0390643	0.00825027	0.000002212033	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0390636	0.00825027	0.00000221287	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0390511	0.00825027	0.000002229496	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	-0.097517	0.0206067	0.000002236595	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	-0.0401712	0.00849024	0.00000224995	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0443759	0.00937903	0.000002250616	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00119073	chr3:187870713	3	187870713	LPP	North shore	-0.0390261	0.00825028	0.000002263098	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.0997119	0.0210879	0.0000022809	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0627379	0.013268	0.000002282769	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02521428	chr3:188083758	3	188083758	LPP	Open sea	-0.01	0.0022	0.0000023	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.05	0.01063	0.0000023	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	TBCE protein levels (SeqId = 11211-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TBCE protein levels (SeqId = 11211-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tubulin-specific chaperone E	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000023	None	Gadd-DA_tbce_protein_levels__seqid___11211-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK10 protein levels (SeqId = 15418-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK10 protein levels (SeqId = 15418-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 10	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000023	None	Gadd-DA_mapk10_protein_levels__seqid___15418-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACTN1 protein levels (SeqId = 9843-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACTN1 protein levels (SeqId = 9843-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-actinin-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000023	None	Gadd-DA_actn1_protein_levels__seqid___9843-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADH6 protein levels (SeqId = 18206-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADH6 protein levels (SeqId = 18206-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alcohol dehydrogenase 6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000023	None	Gadd-DA_adh6_protein_levels__seqid___18206-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRDX1 protein levels (SeqId = 3855-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRDX1 protein levels (SeqId = 3855-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxiredoxin-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000023	None	Gadd-DA_prdx1_protein_levels__seqid___3855-56__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0389955	0.00825029	0.000002304711	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0389933	0.00825029	0.000002307726	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0389862	0.00825029	0.000002317606	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.0448973	0.00950326	0.000002329275	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0389772	0.0082503	0.000002330043	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0389739	0.0082503	0.00000233464	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0389611	0.0082503	0.000002352514	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	-0.0390639	0.00827319	0.000002359868	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0389454	0.00825031	0.000002374581	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0429855	0.00910664	0.000002377451	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK9 protein levels (SeqId = 15604-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK9 protein levels (SeqId = 15604-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 9	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000024	None	Gadd-DA_mapk9_protein_levels__seqid___15604-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPBP protein levels (SeqId = 16765-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPBP protein levels (SeqId = 16765-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet basic protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000024	None	Gadd-DA_ppbp_protein_levels__seqid___16765-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM49B protein levels (SeqId = 19176-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM49B protein levels (SeqId = 19176-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM49B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000024	None	Gadd-DA_fam49b_protein_levels__seqid___19176-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EHD4 protein levels (SeqId = 11421-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EHD4 protein levels (SeqId = 11421-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: EH domain-containing protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000024	None	Gadd-DA_ehd4_protein_levels__seqid___11421-10__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0389245	0.00825031	0.000002404424	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0479544	0.0101645	0.000002405569	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0504028	0.0106902	0.000002440909	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0388974	0.00825032	0.000002443496	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0388909	0.00825033	0.000002452934	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0388904	0.00825033	0.000002453695	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0435932	0.00924845	0.000002456549	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0506907	0.0107561	0.000002466791	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	0.0421074	0.00893487	0.00000246699	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0442386	0.00938826	0.000002474027	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0522268	0.0110857	0.000002485328	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0388682	0.00825033	0.000002486408	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0407099	0.00864252	0.000002494763	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.176555	0.0374873	0.000002499824	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23260255	chr3:187871479	3	187871479	LPP	Island	0.002	0.00043	0.0000025	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	CACNB4 protein levels (SeqId = 11130-158)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CACNB4 protein levels (SeqId = 11130-158)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Voltage-dependent L-type calcium channel subunit beta-4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000025	None	Gadd-DA_cacnb4_protein_levels__seqid___11130-158__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GNRH1 protein levels (SeqId = 5627-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GNRH1 protein levels (SeqId = 5627-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Progonadoliberin-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000025	None	Gadd-DA_gnrh1_protein_levels__seqid___5627-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKCA protein levels (SeqId = 2644-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKCA protein levels (SeqId = 2644-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein kinase C alpha type	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000025	None	Gadd-DA_prkca_protein_levels__seqid___2644-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TAX1BP3 protein levels (SeqId = 12498-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TAX1BP3 protein levels (SeqId = 12498-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tax1-binding protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.99	0.209	0.0000025	None	Gadd-DA_tax1bp3_protein_levels__seqid___12498-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB1B protein levels (SeqId = 19278-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB1B protein levels (SeqId = 19278-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-1B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000025	None	Gadd-DA_rab1b_protein_levels__seqid___19278-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PNP protein levels (SeqId = 15435-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PNP protein levels (SeqId = 15435-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Purine nucleoside phosphorylase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000025	None	Gadd-DA_pnp_protein_levels__seqid___15435-4__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.164859	0.0350353	0.000002551994	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	0.0388193	0.00825035	0.000002559707	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0388133	0.00825035	0.000002568791	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	-0.145236	0.0308747	0.000002570236	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0571709	0.0121533	0.000002572538	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	0.0388109	0.00825035	0.000002572545	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	-0.227616	0.0483976	0.000002581844	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.0387994	0.00825035	0.000002590132	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0387979	0.00825035	0.000002592421	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0387946	0.00825036	0.000002597462	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Battram T	GEO	27886173	2020-09-15	Inflammatory bowel disease	EFO_0003767	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE87640	None	DNA methylation	Inflammatory bowel disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	240	1	Adults	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	0.0215	0.00445	0.0000026	None	27886173_Battram-T_inflammatory_bowel_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse87640
Gadd DA	Generation Scotland	35945220	31/07/2022	NANS protein levels (SeqId = 17802-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NANS protein levels (SeqId = 17802-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sialic acid synthase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000026	None	Gadd-DA_nans_protein_levels__seqid___17802-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MYCBP protein levels (SeqId = 19250-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYCBP protein levels (SeqId = 19250-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: c-Myc-binding protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000026	None	Gadd-DA_mycbp_protein_levels__seqid___19250-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MOBKL1A protein levels (SeqId = 19177-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MOBKL1A protein levels (SeqId = 19177-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MOB kinase activator 1B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000026	None	Gadd-DA_mobkl1a_protein_levels__seqid___19177-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TXNDC12 protein levels (SeqId = 19334-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXNDC12 protein levels (SeqId = 19334-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin domain-containing protein 12	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000026	None	Gadd-DA_txndc12_protein_levels__seqid___19334-62__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VPS4A protein levels (SeqId = 11476-43)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VPS4A protein levels (SeqId = 11476-43)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vacuolar protein sorting-associated protein 4A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000026	None	Gadd-DA_vps4a_protein_levels__seqid___11476-43__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	0.0405569	0.00862662	0.000002607713	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0387841	0.00825036	0.000002613714	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0387822	0.00825036	0.000002616701	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0506937	0.0107873	0.000002633031	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.0387464	0.00825037	0.000002672891	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0503117	0.0107157	0.000002688502	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10666406	chr3:187872353	3	187872353	LPP	Island	-0.00589	0.00122	0.0000027	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	PRG3 protein levels (SeqId = 9015-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRG3 protein levels (SeqId = 9015-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteoglycan 3	774	1	Adults (18-65 years)	Both	European	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	-0.84	0.178	0.0000027	None	Gadd-DA_prg3_protein_levels__seqid___9015-1__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26124569	chr3:187975150	3	187975150	LPP	Open sea	-0.0013	0.00029	0.0000027	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	DOK2 protein levels (SeqId = 14246-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DOK2 protein levels (SeqId = 14246-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Docking protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000027	None	Gadd-DA_dok2_protein_levels__seqid___14246-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB32 protein levels (SeqId = 17778-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB32 protein levels (SeqId = 17778-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-32	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000027	None	Gadd-DA_rab32_protein_levels__seqid___17778-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPHK1 protein levels (SeqId = 4294-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPHK1 protein levels (SeqId = 4294-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sphingosine kinase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000027	None	Gadd-DA_sphk1_protein_levels__seqid___4294-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0441168	0.0093983	0.000002701751	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0457974	0.00975678	0.000002704601	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0506523	0.0107938	0.000002720401	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0386844	0.00825039	0.000002772858	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0410339	0.00875359	0.000002788246	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	WWP1 protein levels (SeqId = 11307-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WWP1 protein levels (SeqId = 11307-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NEDD4-like E3 ubiquitin-protein ligase WWP1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000028	None	Gadd-DA_wwp1_protein_levels__seqid___11307-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADRBK1 protein levels (SeqId = 3347-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADRBK1 protein levels (SeqId = 3347-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-adrenergic receptor kinase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000028	None	Gadd-DA_adrbk1_protein_levels__seqid___3347-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0440156	0.00939744	0.000002841539	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0386381	0.00825041	0.000002849928	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.050139	0.0107071	0.000002855455	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.038629	0.00825041	0.000002865309	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.038627	0.00825041	0.000002868748	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0386175	0.00825041	0.00000288494	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ANXA7 protein levels (SeqId = 18244-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANXA7 protein levels (SeqId = 18244-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Annexin A7	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000029	None	Gadd-DA_anxa7_protein_levels__seqid___18244-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BLVRA protein levels (SeqId = 11382-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BLVRA protein levels (SeqId = 11382-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Biliverdin reductase A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000029	None	Gadd-DA_blvra_protein_levels__seqid___11382-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SGK3 protein levels (SeqId = 10042-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SGK3 protein levels (SeqId = 10042-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase Sgk3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.979	0.209	0.0000029	None	Gadd-DA_sgk3_protein_levels__seqid___10042-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HTRA2 protein levels (SeqId = 3317-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HTRA2 protein levels (SeqId = 3317-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine protease HTRA2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000029	None	Gadd-DA_htra2_protein_levels__seqid___3317-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPF protein levels (SeqId = 9764-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPF protein levels (SeqId = 9764-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein F	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000029	None	Gadd-DA_hnrnpf_protein_levels__seqid___9764-79__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AKR1B1 protein levels (SeqId = 16606-85)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKR1B1 protein levels (SeqId = 16606-85)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aldo-keto reductase family 1 member B1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000029	None	Gadd-DA_akr1b1_protein_levels__seqid___16606-85__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.17146	0.0366441	0.000002903602	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	-0.0554975	0.0118646	0.000002929101	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.071403	0.0152659	0.000002933091	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0475623	0.0101759	0.00000298023	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.164409	0.0351832	0.000002991282	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10666406	chr3:187872353	3	187872353	LPP	Island	0.00031	None	0.000003	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17483	1	Adults (18-65y)	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.017	0.00374	0.000003	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	PARK7 protein levels (SeqId = 19523-215)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PARK7 protein levels (SeqId = 19523-215)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein/nucleic acid deglycase DJ-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.000003	None	Gadd-DA_park7_protein_levels__seqid___19523-215__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ST13 protein levels (SeqId = 18387-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ST13 protein levels (SeqId = 18387-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hsc70-interacting protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.000003	None	Gadd-DA_st13_protein_levels__seqid___18387-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPA2 protein levels (SeqId = 18307-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPA2 protein levels (SeqId = 18307-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inorganic pyrophosphatase 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.000003	None	Gadd-DA_ppa2_protein_levels__seqid___18307-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AIDA protein levels (SeqId = 17347-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AIDA protein levels (SeqId = 17347-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Axin interactor, dorsalization-associated protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.000003	None	Gadd-DA_aida_protein_levels__seqid___17347-80__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHMT2 protein levels (SeqId = 12691-44)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHMT2 protein levels (SeqId = 12691-44)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine hydroxymethyltransferase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.000003	None	Gadd-DA_shmt2_protein_levels__seqid___12691-44__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0495578	0.0106103	0.000003027858	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0385326	0.00825044	0.000003033336	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.038521	0.00825044	0.00000305408	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0385146	0.00825045	0.000003065644	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0385112	0.00825045	0.000003071728	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0385037	0.00825045	0.000003085462	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	AIP protein levels (SeqId = 3839-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AIP protein levels (SeqId = 3839-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AH receptor-interacting protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000031	None	Gadd-DA_aip_protein_levels__seqid___3839-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NME2 protein levels (SeqId = 4249-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NME2 protein levels (SeqId = 4249-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nucleoside diphosphate kinase B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000031	None	Gadd-DA_nme2_protein_levels__seqid___4249-64__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNX8 protein levels (SeqId = 6925-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNX8 protein levels (SeqId = 6925-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sorting nexin-8	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.208	0.0000031	None	Gadd-DA_snx8_protein_levels__seqid___6925-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	OLA1 protein levels (SeqId = 12659-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	OLA1 protein levels (SeqId = 12659-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Obg-like ATPase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000031	None	Gadd-DA_ola1_protein_levels__seqid___12659-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LAP3 protein levels (SeqId = 13959-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LAP3 protein levels (SeqId = 13959-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytosol aminopeptidase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000031	None	Gadd-DA_lap3_protein_levels__seqid___13959-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDC42 protein levels (SeqId = 9840-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDC42 protein levels (SeqId = 9840-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cell division control protein 42 homolog	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000031	None	Gadd-DA_cdc42_protein_levels__seqid___9840-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	0.0384745	0.00825046	0.000003138882	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0384733	0.00825046	0.000003141256	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0538016	0.0115378	0.000003143046	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0384712	0.00825046	0.000003145172	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0011	0.00024	0.0000032	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2V1 protein levels (SeqId = 11626-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2V1 protein levels (SeqId = 11626-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 variant 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000032	None	Gadd-DA_ube2v1_protein_levels__seqid___11626-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UGT2A1 protein levels (SeqId = 8907-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UGT2A1 protein levels (SeqId = 8907-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UDP-glucuronosyltransferase 2A1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000032	None	Gadd-DA_ugt2a1_protein_levels__seqid___8907-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSMD1 protein levels (SeqId = 9598-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSMD1 protein levels (SeqId = 9598-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: CUB and sushi domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.98	0.209	0.0000032	None	Gadd-DA_csmd1_protein_levels__seqid___9598-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF5A protein levels (SeqId = 5888-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF5A protein levels (SeqId = 5888-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 5A-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000032	None	Gadd-DA_eif5a_protein_levels__seqid___5888-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HEXIM1 protein levels (SeqId = 15596-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HEXIM1 protein levels (SeqId = 15596-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein HEXIM1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.208	0.0000032	None	Gadd-DA_hexim1_protein_levels__seqid___15596-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	QDPR protein levels (SeqId = 11257-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QDPR protein levels (SeqId = 11257-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dihydropteridine reductase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000032	None	Gadd-DA_qdpr_protein_levels__seqid___11257-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0384383	0.00825047	0.000003206659	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0603942	0.0129645	0.000003214561	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	0.179916	0.0386317	0.000003229237	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0384252	0.00825047	0.000003231393	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.159641	0.0342804	0.000003232307	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.061691	0.0132496	0.000003251517	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0493005	0.0105897	0.000003259829	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0384036	0.00825048	0.000003272841	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	INPP5B protein levels (SeqId = 12641-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	INPP5B protein levels (SeqId = 12641-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Type II inositol 1,4,5-trisphosphate 5-phosphatase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000033	None	Gadd-DA_inpp5b_protein_levels__seqid___12641-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SKIL protein levels (SeqId = 14670-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SKIL protein levels (SeqId = 14670-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ski-like protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000033	None	Gadd-DA_skil_protein_levels__seqid___14670-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDIA3 protein levels (SeqId = 4719-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDIA3 protein levels (SeqId = 4719-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein disulfide-isomerase A3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000033	None	Gadd-DA_pdia3_protein_levels__seqid___4719-58__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0383869	0.00825049	0.000003305141	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23493553	chr3:188055123	3	188055123	LPP	Open sea	0.0375763	0.00807833	0.000003324194	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10671125	chr3:188401518	3	188401518	LPP	Open sea	0.0383672	0.00825049	0.000003343484	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0383666	0.00825049	0.000003344836	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0383632	0.00825049	0.000003351481	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg02521428	chr3:188083758	3	188083758	LPP	Open sea	-1.23469	0.2657	0.00000336	-	27105112_hiv_infection_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	G3BP1 protein levels (SeqId = 19266-35)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	G3BP1 protein levels (SeqId = 19266-35)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras GTPase-activating protein-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000034	None	Gadd-DA_g3bp1_protein_levels__seqid___19266-35__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PIN4 protein levels (SeqId = 12718-43)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIN4 protein levels (SeqId = 12718-43)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000034	None	Gadd-DA_pin4_protein_levels__seqid___12718-43__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HS3ST4 protein levels (SeqId = 8998-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HS3ST4 protein levels (SeqId = 8998-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heparan sulfate glucosamine 3-O-sulfotransferase 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000034	None	Gadd-DA_hs3st4_protein_levels__seqid___8998-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ETS2 protein levels (SeqId = 12350-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ETS2 protein levels (SeqId = 12350-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein C-ets-2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000034	None	Gadd-DA_ets2_protein_levels__seqid___12350-86__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GCLM protein levels (SeqId = 18214-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GCLM protein levels (SeqId = 18214-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutamate--cysteine ligase regulatory subunit	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000034	None	Gadd-DA_gclm_protein_levels__seqid___18214-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0402865	0.00867198	0.000003420525	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0383222	0.00825051	0.000003433139	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.038309	0.00825051	0.000003459898	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0394424	0.00849484	0.000003462028	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0383025	0.00825051	0.000003472998	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0383005	0.00825051	0.000003477075	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PLCB1 protein levels (SeqId = 11354-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLCB1 protein levels (SeqId = 11354-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000035	None	Gadd-DA_plcb1_protein_levels__seqid___11354-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DTD2 protein levels (SeqId = 18280-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DTD2 protein levels (SeqId = 18280-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: D-aminoacyl-tRNA deacylase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000035	None	Gadd-DA_dtd2_protein_levels__seqid___18280-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VTA1 protein levels (SeqId = 4209-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VTA1 protein levels (SeqId = 4209-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vacuolar protein sorting-associated protein VTA1 homolog	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000035	None	Gadd-DA_vta1_protein_levels__seqid___4209-60__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0382864	0.00825052	0.00000350606	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0499318	0.0107641	0.000003535528	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0406459	0.0087641	0.000003552354	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0456392	0.00984655	0.000003599304	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	COL9A1 protein levels (SeqId = 6631-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COL9A1 protein levels (SeqId = 6631-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen alpha-1(IX) chain	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.969	0.209	0.0000036	None	Gadd-DA_col9a1_protein_levels__seqid___6631-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB6B protein levels (SeqId = 14271-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB6B protein levels (SeqId = 14271-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-6B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.208	0.0000036	None	Gadd-DA_rab6b_protein_levels__seqid___14271-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TOLLIP protein levels (SeqId = 13963-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TOLLIP protein levels (SeqId = 13963-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Toll-interacting protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000036	None	Gadd-DA_tollip_protein_levels__seqid___13963-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNM2 protein levels (SeqId = 11572-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNM2 protein levels (SeqId = 11572-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dynamin-2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000036	None	Gadd-DA_dnm2_protein_levels__seqid___11572-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GSK3A protein levels (SeqId = 3441-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSK3A protein levels (SeqId = 3441-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycogen synthase kinase-3 alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000036	None	Gadd-DA_gsk3a_protein_levels__seqid___3441-64__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDLIM1 protein levels (SeqId = 11428-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDLIM1 protein levels (SeqId = 11428-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PDZ and LIM domain protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000036	None	Gadd-DA_pdlim1_protein_levels__seqid___11428-31__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0382376	0.00825053	0.000003607799	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0401397	0.00866246	0.000003621832	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0382279	0.00825054	0.000003628256	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0382183	0.00825054	0.000003648829	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	0.0381993	0.00825055	0.000003689617	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0381975	0.00825055	0.00000369351	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PRG3 protein levels (SeqId = 9015-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRG3 protein levels (SeqId = 9015-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteoglycan 3	774	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-1.02	0.221	0.0000037	None	Gadd-DA_prg3_protein_levels__seqid___9015-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB1 protein levels (SeqId = 3852-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB1 protein levels (SeqId = 3852-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000037	None	Gadd-DA_dnajb1_protein_levels__seqid___3852-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDE11A protein levels (SeqId = 5252-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDE11A protein levels (SeqId = 5252-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000037	None	Gadd-DA_pde11a_protein_levels__seqid___5252-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VPS26A protein levels (SeqId = 19293-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VPS26A protein levels (SeqId = 19293-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vacuolar protein sorting-associated protein 26A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000037	None	Gadd-DA_vps26a_protein_levels__seqid___19293-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSP90AB1 protein levels (SeqId = 5467-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSP90AB1 protein levels (SeqId = 5467-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heat shock protein HSP 90-beta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000037	None	Gadd-DA_hsp90ab1_protein_levels__seqid___5467-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AASDHPPT protein levels (SeqId = 17320-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AASDHPPT protein levels (SeqId = 17320-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000037	None	Gadd-DA_aasdhppt_protein_levels__seqid___17320-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0381891	0.00825055	0.000003711665	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.0463544	0.0100224	0.000003776831	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24123854	chr3:187973091	3	187973091	LPP	Open sea	0.0381559	0.00825056	0.000003784486	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0405651	0.00877152	0.000003784569	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.163406	0.0353416	0.00000379677	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.27	0.0591	0.0000038	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13282252	chr3:188581493	3	188581493	LPP	Open sea	-0.02711	0.0057	0.0000038	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	NUDC protein levels (SeqId = 8887-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUDC protein levels (SeqId = 8887-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear migration protein nudC	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000038	None	Gadd-DA_nudc_protein_levels__seqid___8887-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SMAD3 protein levels (SeqId = 10363-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMAD3 protein levels (SeqId = 10363-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mothers against decapentaplegic homolog 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000038	None	Gadd-DA_smad3_protein_levels__seqid___10363-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF4H protein levels (SeqId = 5885-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF4H protein levels (SeqId = 5885-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 4H	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000038	None	Gadd-DA_eif4h_protein_levels__seqid___5885-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PURB protein levels (SeqId = 18300-39)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PURB protein levels (SeqId = 18300-39)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcriptional activator protein Pur-beta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000038	None	Gadd-DA_purb_protein_levels__seqid___18300-39__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0459131	0.00993364	0.000003833269	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0533904	0.011555	0.000003859821	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	-0.0381215	0.00825057	0.000003861255	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	0.0381166	0.00825057	0.000003872454	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0381112	0.00825057	0.00000388474	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0381096	0.00825057	0.000003888271	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	1.4	0.3	0.0000039	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ABHD10 protein levels (SeqId = 17370-186)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ABHD10 protein levels (SeqId = 17370-186)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mycophenolic acid acyl-glucuronide esterase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000039	None	Gadd-DA_abhd10_protein_levels__seqid___17370-186__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACADVL protein levels (SeqId = 19262-219)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACADVL protein levels (SeqId = 19262-219)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000039	None	Gadd-DA_acadvl_protein_levels__seqid___19262-219__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ALDH1A3 protein levels (SeqId = 9835-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALDH1A3 protein levels (SeqId = 9835-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aldehyde dehydrogenase family 1 member A3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.97	0.209	0.0000039	None	Gadd-DA_aldh1a3_protein_levels__seqid___9835-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.0503524	0.0109028	0.000003901569	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0380995	0.00825058	0.000003911254	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0380957	0.00825058	0.000003919879	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.0380787	0.00825058	0.00000395909	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP1CC protein levels (SeqId = 19295-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP1CC protein levels (SeqId = 19295-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.000004	None	Gadd-DA_ppp1cc_protein_levels__seqid___19295-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAC2 protein levels (SeqId = 18950-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAC2 protein levels (SeqId = 18950-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related C3 botulinum toxin substrate 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.000004	None	Gadd-DA_rac2_protein_levels__seqid___18950-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DMKN protein levels (SeqId = 5963-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DMKN protein levels (SeqId = 5963-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dermokine	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.965	0.209	0.000004	None	Gadd-DA_dmkn_protein_levels__seqid___5963-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GHRL protein levels (SeqId = 6518-85)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GHRL protein levels (SeqId = 6518-85)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Appetite-regulating hormone	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.961	0.209	0.000004	None	Gadd-DA_ghrl_protein_levels__seqid___6518-85__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	YWHAB protein levels (SeqId = 4707-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YWHAB protein levels (SeqId = 4707-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 14-3-3 protein eta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.000004	None	Gadd-DA_ywhab_protein_levels__seqid___4707-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	INPP5E protein levels (SeqId = 11370-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	INPP5E protein levels (SeqId = 11370-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 72 kDa inositol polyphosphate 5-phosphatase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.000004	None	Gadd-DA_inpp5e_protein_levels__seqid___11370-20__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.063	0.0136569	0.000004001462	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0380566	0.00825059	0.000004010541	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0618434	0.0134086	0.000004017576	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0380531	0.00825059	0.000004018603	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg22209756	chr3:187901412	3	187901412	LPP	Open sea	-0.208469	0.0452282	0.000004068058	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.038024	0.0082506	0.00000408749	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0413932	0.00898284	0.000004099366	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.14	0.0313	0.0000041	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3GL2 protein levels (SeqId = 12499-108)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3GL2 protein levels (SeqId = 12499-108)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endophilin-A1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000041	None	Gadd-DA_sh3gl2_protein_levels__seqid___12499-108__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GABARAP protein levels (SeqId = 17735-130)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GABARAP protein levels (SeqId = 17735-130)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-aminobutyric acid receptor-associated protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000041	None	Gadd-DA_gabarap_protein_levels__seqid___17735-130__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LIN7B protein levels (SeqId = 15612-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LIN7B protein levels (SeqId = 15612-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein lin-7 homolog B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000041	None	Gadd-DA_lin7b_protein_levels__seqid___15612-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SRP14 protein levels (SeqId = 17510-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SRP14 protein levels (SeqId = 17510-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal recognition particle 14 kDa protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000041	None	Gadd-DA_srp14_protein_levels__seqid___17510-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CHMP2A protein levels (SeqId = 17728-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHMP2A protein levels (SeqId = 17728-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Charged multivesicular body protein 2a	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000041	None	Gadd-DA_chmp2a_protein_levels__seqid___17728-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ERP29 protein levels (SeqId = 13728-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ERP29 protein levels (SeqId = 13728-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endoplasmic reticulum resident protein 29	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000041	None	Gadd-DA_erp29_protein_levels__seqid___13728-19__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.270275	0.0586753	0.000004128401	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	0.0374967	0.00814003	0.000004130277	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0505484	0.0109741	0.00000413661	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0413876	0.00898534	0.000004136869	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0379972	0.00825061	0.00000415164	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.202268	0.0439256	0.000004158113	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.045116	0.00979862	0.000004172796	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0412445	0.0089583	0.000004178332	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0557327	0.0121086	0.000004205094	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.061208	0.0132997	0.000004215539	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0446913	0.00971154	0.000004222078	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0432105	0.00939077	0.000004232217	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	-0.0379563	0.00825062	0.000004251736	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0379515	0.00825062	0.000004263652	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.193033	0.0419791	0.00000428929	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJC10 protein levels (SeqId = 8297-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJC10 protein levels (SeqId = 8297-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily C member 10	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000043	None	Gadd-DA_dnajc10_protein_levels__seqid___8297-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CACYBP protein levels (SeqId = 12432-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CACYBP protein levels (SeqId = 12432-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcyclin-binding protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000043	None	Gadd-DA_cacybp_protein_levels__seqid___12432-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZADH2 protein levels (SeqId = 17345-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZADH2 protein levels (SeqId = 17345-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prostaglandin reductase 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.961	0.209	0.0000043	None	Gadd-DA_zadh2_protein_levels__seqid___17345-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BPNT1 protein levels (SeqId = 17814-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BPNT1 protein levels (SeqId = 17814-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 3'(2'),5'-bisphosphate nucleotidase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000043	None	Gadd-DA_bpnt1_protein_levels__seqid___17814-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NCK2 protein levels (SeqId = 13615-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NCK2 protein levels (SeqId = 13615-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytoplasmic protein NCK2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000043	None	Gadd-DA_nck2_protein_levels__seqid___13615-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB4 protein levels (SeqId = 18884-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB4 protein levels (SeqId = 18884-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000043	None	Gadd-DA_dnajb4_protein_levels__seqid___18884-22__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.018	0.00396	0.0000043	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0379274	0.00825063	0.000004323928	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0397658	0.00865062	0.000004324787	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0379239	0.00825063	0.000004332546	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0766655	0.0166817	0.000004347343	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.139961	0.030469	0.000004388599	None	39706196_Hannah-M.-Smith_bmi_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.17	0.037	0.0000044	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0384917	0.0083808	0.000004408819	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0817103	0.0177929	0.000004420474	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0378711	0.00825065	0.000004467541	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	0.0378638	0.00825065	0.000004486654	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.025	0.00555	0.0000045	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	SBDS protein levels (SeqId = 3866-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SBDS protein levels (SeqId = 3866-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribosome maturation protein SBDS	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000045	None	Gadd-DA_sbds_protein_levels__seqid___3866-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BAD protein levels (SeqId = 5870-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BAD protein levels (SeqId = 5870-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bcl2-associated agonist of cell death	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000045	None	Gadd-DA_bad_protein_levels__seqid___5870-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBQLN4 protein levels (SeqId = 12720-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBQLN4 protein levels (SeqId = 12720-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquilin-4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000045	None	Gadd-DA_ubqln4_protein_levels__seqid___12720-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COX5A protein levels (SeqId = 18226-148)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COX5A protein levels (SeqId = 18226-148)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytochrome c oxidase subunit 5A, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000045	None	Gadd-DA_cox5a_protein_levels__seqid___18226-148__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDGFD protein levels (SeqId = 17140-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDGFD protein levels (SeqId = 17140-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet-derived growth factor D	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000045	None	Gadd-DA_pdgfd_protein_levels__seqid___17140-57__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0378563	0.00825065	0.000004506126	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0410396	0.00894521	0.000004514826	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0378236	0.00825066	0.000004592457	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Neumann A	ALSPAC, GENR, INMA, NEST, PREDO	33184255	2020-11-12	ADHD	EFO_0003888	At birth	Supplementary data adhd_birth_results	ADHD	DNA methylation	maternal age, education level, smoking, gestational age, sex, cell composition (reference based)	ADHD score	Beta Values	Illumina HumanMethylation450	Cord Blood	None	2477	5	Infants	Both	European, African	cg21427213	chr3:187872975	3	187872975	LPP	South shore	-1.579	0.587	0.0000046	None	33184255_Neumann-A_adhd_at_birth
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMA protein levels (SeqId = 3440-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMA protein levels (SeqId = 3440-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme A	774	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.89	0.194	0.0000046	None	Gadd-DA_gzma_protein_levels__seqid___3440-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KDELC2 protein levels (SeqId = 8296-117)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KDELC2 protein levels (SeqId = 8296-117)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein O-glucosyltransferase 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000046	None	Gadd-DA_kdelc2_protein_levels__seqid___8296-117__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NACA protein levels (SeqId = 3854-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NACA protein levels (SeqId = 3854-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nascent polypeptide-associated complex subunit alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000046	None	Gadd-DA_naca_protein_levels__seqid___3854-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	YARS protein levels (SeqId = 19270-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YARS protein levels (SeqId = 19270-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine--tRNA ligase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000046	None	Gadd-DA_yars_protein_levels__seqid___19270-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSD17B10 protein levels (SeqId = 4217-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSD17B10 protein levels (SeqId = 4217-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 3-hydroxyacyl-CoA dehydrogenase type-2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000046	None	Gadd-DA_hsd17b10_protein_levels__seqid___4217-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGAP5 protein levels (SeqId = 14748-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGAP5 protein levels (SeqId = 14748-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 5	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000046	None	Gadd-DA_arhgap5_protein_levels__seqid___14748-31__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0378176	0.00825067	0.000004608547	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0378003	0.00825067	0.000004655027	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0377919	0.00825067	0.000004677645	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SMAD2 protein levels (SeqId = 10364-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMAD2 protein levels (SeqId = 10364-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mothers against decapentaplegic homolog 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000047	None	Gadd-DA_smad2_protein_levels__seqid___10364-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ROCK2 protein levels (SeqId = 13654-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ROCK2 protein levels (SeqId = 13654-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho-associated protein kinase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000047	None	Gadd-DA_rock2_protein_levels__seqid___13654-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2I protein levels (SeqId = 2877-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2I protein levels (SeqId = 2877-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SUMO-conjugating enzyme UBC9	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000047	None	Gadd-DA_ube2i_protein_levels__seqid___2877-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0377677	0.00825068	0.000004743754	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0377662	0.00825068	0.000004747818	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0408307	0.00892084	0.00000475549	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05548945	chr3:188550738	3	188550738	LPP	Open sea	0.0041	0.0009	0.0000048	None	33450751_Mulder-RH_sex_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	FOXM1 protein levels (SeqId = 10056-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FOXM1 protein levels (SeqId = 10056-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Forkhead box protein M1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000048	None	Gadd-DA_foxm1_protein_levels__seqid___10056-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAD23A protein levels (SeqId = 10058-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAD23A protein levels (SeqId = 10058-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UV excision repair protein RAD23 homolog A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000048	None	Gadd-DA_rad23a_protein_levels__seqid___10058-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPE protein levels (SeqId = 12646-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPE protein levels (SeqId = 12646-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribulose-phosphate 3-epimerase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000048	None	Gadd-DA_rpe_protein_levels__seqid___12646-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDE6D protein levels (SeqId = 13491-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDE6D protein levels (SeqId = 13491-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000048	None	Gadd-DA_pde6d_protein_levels__seqid___13491-40__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0377468	0.00825069	0.000004801561	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0377464	0.00825069	0.000004802539	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0428644	0.00937394	0.000004853784	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00136852	chr3:188350489	3	188350489	LPP	Open sea	-0.0049	0.0011	0.0000049	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	1.8	0.401	0.0000049	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	USO1 protein levels (SeqId = 13639-101)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	USO1 protein levels (SeqId = 13639-101)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: General vesicular transport factor p115	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000049	None	Gadd-DA_uso1_protein_levels__seqid___13639-101__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HIBCH protein levels (SeqId = 12396-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HIBCH protein levels (SeqId = 12396-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000049	None	Gadd-DA_hibch_protein_levels__seqid___12396-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0377095	0.0082507	0.000004906152	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.233721	0.0511437	0.000004911724	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0635405	0.0139052	0.000004927275	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0376995	0.0082507	0.000004934607	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0376961	0.0082507	0.000004944277	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0376891	0.00825071	0.000004964438	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.121755	0.0266588	0.000004984067	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.064928	0.0142164	0.000004985359	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0444543	0.00973431	0.000004993463	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06547766	chr3:187930704	3	187930704	LPP	Open sea	0.0052	None	0.000005	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26318252	chr3:188281073	3	188281073	LPP	Open sea	0.0048	None	0.000005	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	DRG1 protein levels (SeqId = 17849-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DRG1 protein levels (SeqId = 17849-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Developmentally-regulated GTP-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.000005	None	Gadd-DA_drg1_protein_levels__seqid___17849-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PECR protein levels (SeqId = 17776-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PECR protein levels (SeqId = 17776-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxisomal trans-2-enoyl-CoA reductase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.000005	None	Gadd-DA_pecr_protein_levels__seqid___17776-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPIE protein levels (SeqId = 5238-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPIE protein levels (SeqId = 5238-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase E	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.000005	None	Gadd-DA_ppie_protein_levels__seqid___5238-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BRICD5 protein levels (SeqId = 6612-90)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BRICD5 protein levels (SeqId = 6612-90)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BRICHOS domain-containing protein 5	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.000005	None	Gadd-DA_bricd5_protein_levels__seqid___6612-90__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0376482	0.00825072	0.000005083167	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05762680	chr3:188405973	3	188405973	LPP	Open sea	0.005	0.0011	0.0000051	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21779805	chr3:187982495	3	187982495	LPP	Open sea	-0.0068	0.0015	0.0000051	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	PTEN protein levels (SeqId = 3831-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTEN protein levels (SeqId = 3831-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.96	0.209	0.0000051	None	Gadd-DA_pten_protein_levels__seqid___3831-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SELP protein levels (SeqId = 4154-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SELP protein levels (SeqId = 4154-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: P-selectin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000051	None	Gadd-DA_selp_protein_levels__seqid___4154-57__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0380548	0.00834355	0.000005132862	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0413533	0.00907149	0.000005191075	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0586745	0.0128716	0.000005194656	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0376098	0.00825073	0.000005196971	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.022	0.00477	0.0000052	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPK3 protein levels (SeqId = 2855-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPK3 protein levels (SeqId = 2855-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitogen-activated protein kinase 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000052	None	Gadd-DA_mapk3_protein_levels__seqid___2855-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNTA1 protein levels (SeqId = 19274-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNTA1 protein levels (SeqId = 19274-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-1-syntrophin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000052	None	Gadd-DA_snta1_protein_levels__seqid___19274-80__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CIRBP protein levels (SeqId = 12724-81)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CIRBP protein levels (SeqId = 12724-81)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cold-inducible RNA-binding protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000052	None	Gadd-DA_cirbp_protein_levels__seqid___12724-81__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GABARAPL2 protein levels (SeqId = 12494-99)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GABARAPL2 protein levels (SeqId = 12494-99)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-aminobutyric acid receptor-associated protein-like 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000052	None	Gadd-DA_gabarapl2_protein_levels__seqid___12494-99__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EPB41L1 protein levels (SeqId = 13993-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPB41L1 protein levels (SeqId = 13993-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Band 4.1-like protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000052	None	Gadd-DA_epb41l1_protein_levels__seqid___13993-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HDLBP protein levels (SeqId = 13570-43)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDLBP protein levels (SeqId = 13570-43)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vigilin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.208	0.0000052	None	Gadd-DA_hdlbp_protein_levels__seqid___13570-43__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.0386424	0.0084777	0.000005203029	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.037592	0.00825074	0.000005250749	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.0451263	0.00990804	0.000005292873	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CLTA protein levels (SeqId = 19257-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLTA protein levels (SeqId = 19257-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Clathrin light chain A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000053	None	Gadd-DA_clta_protein_levels__seqid___19257-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGEF1 protein levels (SeqId = 13976-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGEF1 protein levels (SeqId = 13976-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho guanine nucleotide exchange factor 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000053	None	Gadd-DA_arhgef1_protein_levels__seqid___13976-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0375719	0.00825074	0.000005311873	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0375707	0.00825074	0.000005315703	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0375629	0.00825074	0.000005339484	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.037551	0.00825075	0.000005376237	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0375492	0.00825075	0.000005381786	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05762680	chr3:188405973	3	188405973	LPP	Open sea	-0.00052	0.00011	0.0000054	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21176488	chr3:188251742	3	188251742	LPP	Open sea	-0.00094	0.00021	0.0000054	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	CAPN1 protein levels (SeqId = 2668-70)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAPN1 protein levels (SeqId = 2668-70)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calpain-1 catalytic subunit|Calpain small subunit 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000054	None	Gadd-DA_capn1_protein_levels__seqid___2668-70__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DARS protein levels (SeqId = 12675-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DARS protein levels (SeqId = 12675-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aspartate--tRNA ligase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000054	None	Gadd-DA_dars_protein_levels__seqid___12675-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HPRT1 protein levels (SeqId = 19290-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HPRT1 protein levels (SeqId = 19290-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hypoxanthine-guanine phosphoribosyltransferase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000054	None	Gadd-DA_hprt1_protein_levels__seqid___19290-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	0.0398151	0.00875208	0.000005427915	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0445697	0.00979952	0.00000545525	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0544097	0.0119646	0.000005470752	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0375199	0.00825076	0.000005473479	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0375179	0.00825076	0.00000547971	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0375139	0.00825076	0.000005492378	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12120430	chr3:187935971	3	187935971	LPP	Open sea	0.0006	None	0.0000055	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.2	0.044	0.0000055	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ACOT13 protein levels (SeqId = 17675-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACOT13 protein levels (SeqId = 17675-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-coenzyme A thioesterase 13	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000055	None	Gadd-DA_acot13_protein_levels__seqid___17675-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BIRC2 protein levels (SeqId = 10046-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BIRC2 protein levels (SeqId = 10046-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Baculoviral IAP repeat-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000055	None	Gadd-DA_birc2_protein_levels__seqid___10046-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MRPL21 protein levels (SeqId = 8942-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MRPL21 protein levels (SeqId = 8942-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 39S ribosomal protein L21, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000055	None	Gadd-DA_mrpl21_protein_levels__seqid___8942-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSNK2A1 protein levels (SeqId = 5225-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSNK2A1 protein levels (SeqId = 5225-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Casein kinase II subunit beta|Casein kinase II subunit alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000055	None	Gadd-DA_csnk2a1_protein_levels__seqid___5225-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSH1 protein levels (SeqId = 13103-125)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSH1 protein levels (SeqId = 13103-125)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chorionic somatomammotropin hormone 2|Chorionic somatomammotropin hormone 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000055	None	Gadd-DA_csh1_protein_levels__seqid___13103-125__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDOST protein levels (SeqId = 17161-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDOST protein levels (SeqId = 17161-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000055	None	Gadd-DA_ddost_protein_levels__seqid___17161-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CFL1 protein levels (SeqId = 4203-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CFL1 protein levels (SeqId = 4203-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cofilin-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000055	None	Gadd-DA_cfl1_protein_levels__seqid___4203-50__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0492447	0.010835	0.00000553883	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-1.115009	0.2455	0.00000558	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12314978	chr3:188324556	3	188324556	LPP	Open sea	0.0374826	0.00825077	0.00000559219	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMA protein levels (SeqId = 3440-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMA protein levels (SeqId = 3440-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme A	774	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.58	0.128	0.0000056	None	Gadd-DA_gzma_protein_levels__seqid___3440-7__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16915803	chr3:187909561	3	187909561	LPP	Open sea	0.0032	None	0.0000056	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg17392043	chr3:188495102	3	188495102	LPP	Open sea	-0.0086	0.0019	0.0000056	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	GDI1 protein levels (SeqId = 16810-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GDI1 protein levels (SeqId = 16810-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rab GDP dissociation inhibitor alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000056	None	Gadd-DA_gdi1_protein_levels__seqid___16810-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPT1 protein levels (SeqId = 9244-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPT1 protein levels (SeqId = 9244-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Palmitoyl-protein thioesterase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000056	None	Gadd-DA_ppt1_protein_levels__seqid___9244-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP3R1 protein levels (SeqId = 15545-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP3R1 protein levels (SeqId = 15545-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcineurin subunit B type 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000056	None	Gadd-DA_ppp3r1_protein_levels__seqid___15545-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDE1A protein levels (SeqId = 5253-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDE1A protein levels (SeqId = 5253-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000056	None	Gadd-DA_pde1a_protein_levels__seqid___5253-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0393679	0.0086664	0.000005601135	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0374745	0.00825077	0.000005618223	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	0.0374683	0.00825077	0.000005638328	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0593285	0.0130706	0.00000569476	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.01699	0.00364	0.0000057	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPPA protein levels (SeqId = 4148-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPPA protein levels (SeqId = 4148-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pappalysin-1	774	1	Adults (18-65 years)	Both	European	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	-0.81	0.178	0.0000057	None	Gadd-DA_pappa_protein_levels__seqid___4148-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HS3ST3A1 protein levels (SeqId = 8268-98)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HS3ST3A1 protein levels (SeqId = 8268-98)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heparan sulfate glucosamine 3-O-sulfotransferase 3A1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000057	None	Gadd-DA_hs3st3a1_protein_levels__seqid___8268-98__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS6KB1 protein levels (SeqId = 15608-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS6KB1 protein levels (SeqId = 15608-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribosomal protein S6 kinase beta-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000057	None	Gadd-DA_rps6kb1_protein_levels__seqid___15608-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PARVA protein levels (SeqId = 13434-172)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PARVA protein levels (SeqId = 13434-172)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-parvin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.208	0.0000057	None	Gadd-DA_parva_protein_levels__seqid___13434-172__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COMMD9 protein levels (SeqId = 17683-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COMMD9 protein levels (SeqId = 17683-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: COMM domain-containing protein 9	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000057	None	Gadd-DA_commd9_protein_levels__seqid___17683-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.037433	0.00825078	0.000005753807	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.0386748	0.00852498	0.000005760964	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0374197	0.00825079	0.000005797962	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CDKN1A protein levels (SeqId = 18291-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDKN1A protein levels (SeqId = 18291-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cyclin-dependent kinase inhibitor 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000058	None	Gadd-DA_cdkn1a_protein_levels__seqid___18291-8__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0430005	0.00948612	0.000005861536	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CGB2 protein levels (SeqId = 6213-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CGB2 protein levels (SeqId = 6213-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Choriogonadotropin subunit beta variant 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.945	0.209	0.0000059	None	Gadd-DA_cgb2_protein_levels__seqid___6213-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDKN2D protein levels (SeqId = 12376-85)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDKN2D protein levels (SeqId = 12376-85)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cyclin-dependent kinase 4 inhibitor D	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000059	None	Gadd-DA_cdkn2d_protein_levels__seqid___12376-85__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.037388	0.0082508	0.000005904462	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0487458	0.010758	0.000005913845	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.044242	0.00976517	0.000005928307	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0494746	0.0109214	0.000005943542	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	-0.0418872	0.00924996	0.000005990902	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PDCD6IP protein levels (SeqId = 18174-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDCD6IP protein levels (SeqId = 18174-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Programmed cell death 6-interacting protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.000006	None	Gadd-DA_pdcd6ip_protein_levels__seqid___18174-79__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TESC protein levels (SeqId = 12831-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TESC protein levels (SeqId = 12831-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcineurin B homologous protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.000006	None	Gadd-DA_tesc_protein_levels__seqid___12831-21__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0373507	0.00825081	0.000006032247	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0373377	0.00825081	0.000006077473	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0373351	0.00825082	0.000006086374	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15213399	chr3:188415784	3	188415784	LPP	Open sea	0.02951	0.00634	0.0000061	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	TAF15 protein levels (SeqId = 16865-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TAF15 protein levels (SeqId = 16865-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: TATA-binding protein-associated factor 2N	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000061	None	Gadd-DA_taf15_protein_levels__seqid___16865-62__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TFAM protein levels (SeqId = 9952-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TFAM protein levels (SeqId = 9952-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription factor A, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000061	None	Gadd-DA_tfam_protein_levels__seqid___9952-57__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0393782	0.00870498	0.000006126178	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	-0.237271	0.052467	0.000006155877	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0373088	0.00825082	0.000006178891	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.037306	0.00825082	0.000006188817	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	1.3	0.29	0.0000062	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS6KA3 protein levels (SeqId = 3469-74)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS6KA3 protein levels (SeqId = 3469-74)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribosomal protein S6 kinase alpha-3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.208	0.0000062	None	Gadd-DA_rps6ka3_protein_levels__seqid___3469-74__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IRF3 protein levels (SeqId = 17151-84)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IRF3 protein levels (SeqId = 17151-84)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon regulatory factor 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000062	None	Gadd-DA_irf3_protein_levels__seqid___17151-84__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF3G protein levels (SeqId = 11454-87)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF3G protein levels (SeqId = 11454-87)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 3 subunit G	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000062	None	Gadd-DA_eif3g_protein_levels__seqid___11454-87__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RGS10 protein levels (SeqId = 11634-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RGS10 protein levels (SeqId = 11634-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Regulator of G-protein signaling 10	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000062	None	Gadd-DA_rgs10_protein_levels__seqid___11634-32__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02994616	chr3:188579819	3	188579819	LPP	Open sea	0.0372998	0.00825083	0.000006210759	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0372878	0.00825083	0.000006253583	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0372877	0.00825083	0.000006254035	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0372868	0.00825083	0.000006257142	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0372864	0.00825083	0.000006258728	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0392369	0.0086825	0.000006259702	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.050009	0.0110687	0.000006289679	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15338041	chr3:187942570	3	187942570	LPP	Open sea	-0.01751	0.00377	0.0000063	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	HSPC159 protein levels (SeqId = 18236-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSPC159 protein levels (SeqId = 18236-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Galectin-related protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000063	None	Gadd-DA_hspc159_protein_levels__seqid___18236-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DOK1 protein levels (SeqId = 16831-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DOK1 protein levels (SeqId = 16831-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Docking protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000063	None	Gadd-DA_dok1_protein_levels__seqid___16831-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0372632	0.00825084	0.000006342157	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0574884	0.0127297	0.000006349049	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.221686	0.0490974	0.000006366805	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0737211	0.0163269	0.00000637177	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.037248	0.00825084	0.000006397424	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TCF4 protein levels (SeqId = 19144-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TCF4 protein levels (SeqId = 19144-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription factor 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000064	None	Gadd-DA_tcf4_protein_levels__seqid___19144-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPBP protein levels (SeqId = 2790-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPBP protein levels (SeqId = 2790-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet basic protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.95	0.209	0.0000064	None	Gadd-DA_ppbp_protein_levels__seqid___2790-54__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0372444	0.00825084	0.000006410658	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0372347	0.00825085	0.000006446251	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0372341	0.00825085	0.000006448555	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM150B protein levels (SeqId = 6284-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM150B protein levels (SeqId = 6284-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ALK and LTK ligand 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000065	None	Gadd-DA_fam150b_protein_levels__seqid___6284-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PIP4K2B protein levels (SeqId = 18232-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIP4K2B protein levels (SeqId = 18232-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000065	None	Gadd-DA_pip4k2b_protein_levels__seqid___18232-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3BGRL3 protein levels (SeqId = 17490-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3BGRL3 protein levels (SeqId = 17490-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SH3 domain-binding glutamic acid-rich-like protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000065	None	Gadd-DA_sh3bgrl3_protein_levels__seqid___17490-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0372193	0.00825085	0.000006503551	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0577424	0.0128027	0.000006527389	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	IGBP1 protein levels (SeqId = 12358-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IGBP1 protein levels (SeqId = 12358-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000066	None	Gadd-DA_igbp1_protein_levels__seqid___12358-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.0371918	0.00825086	0.000006606509	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03945529	chr3:188024721	3	188024721	LPP	Open sea	-0.0371805	0.00825086	0.000006649181	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0368638	0.00818105	0.000006657152	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0371757	0.00825086	0.000006667428	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	-0.179387	0.0398201	0.000006683122	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	SRC protein levels (SeqId = 15433-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SRC protein levels (SeqId = 15433-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proto-oncogene tyrosine-protein kinase Src	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000067	None	Gadd-DA_src_protein_levels__seqid___15433-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SAR1A protein levels (SeqId = 17726-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SAR1A protein levels (SeqId = 17726-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GTP-binding protein SAR1a	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000067	None	Gadd-DA_sar1a_protein_levels__seqid___17726-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NUDT16L1 protein levels (SeqId = 12497-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUDT16L1 protein levels (SeqId = 12497-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tudor-interacting repair regulator protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000067	None	Gadd-DA_nudt16l1_protein_levels__seqid___12497-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGDIB protein levels (SeqId = 9846-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGDIB protein levels (SeqId = 9846-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GDP-dissociation inhibitor 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000067	None	Gadd-DA_arhgdib_protein_levels__seqid___9846-32__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0371662	0.00825087	0.000006703797	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.037166	0.00825087	0.00000670447	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3BGRL2 protein levels (SeqId = 19113-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3BGRL2 protein levels (SeqId = 19113-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SH3 domain-binding glutamic acid-rich-like protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000068	None	Gadd-DA_sh3bgrl2_protein_levels__seqid___19113-66__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.134088	0.0297912	0.00000680966	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0597427	0.0132743	0.000006827555	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0371302	0.00825088	0.000006842848	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.0570672	0.0126812	0.0000068435	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21101580	chr3:188545164	3	188545164	LPP	Open sea	0.0371253	0.00825088	0.000006861808	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0371246	0.00825088	0.000006864478	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0371175	0.00825088	0.000006892467	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CTRC protein levels (SeqId = 5626-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CTRC protein levels (SeqId = 5626-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chymotrypsin-C	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000069	None	Gadd-DA_ctrc_protein_levels__seqid___5626-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UNC45A protein levels (SeqId = 13082-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UNC45A protein levels (SeqId = 13082-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein unc-45 homolog A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000069	None	Gadd-DA_unc45a_protein_levels__seqid___13082-9__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.021	0.00466	0.0000069	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0371066	0.00825089	0.000006935217	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02765	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02765	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0370911	0.00825089	0.000006996917	P02765	41361833_Josephine_Robertson_P02765_OSCA_model_1
Cardenas A	Project Viva	31300640	Jul 12, 2019	fractional exhaled nitric oxide (FeNO)	EFO_0005536	None	Supplementary Data 2	DNA methylation	fractional exhaled nitric oxide (FeNO)	Age, Sex, Smoking, Cell composition (reference free), Batch effects, Ancestry (other), Body mass index, Education, sine and cosine of season at sample collection	Beta values	ppb	Illumina HumanMethylationEPIC	nasal epithelium	None	517	1	Children	Both	Other	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	-2.25	0.496	0.000007	SE manually calculated	31300640_Cardenas-A_fractional_exhaled_nitric_oxide__feno_
Gadd DA	Generation Scotland	35945220	31/07/2022	ACBD6 protein levels (SeqId = 10075-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACBD6 protein levels (SeqId = 10075-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-CoA-binding domain-containing protein 6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.000007	None	Gadd-DA_acbd6_protein_levels__seqid___10075-75__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.167904	0.0373533	0.000007000933	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0370834	0.00825089	0.000007027607	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0389118	0.00865792	0.000007031399	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	0.03842	0.00854877	0.000007036457	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21101580	chr3:188545164	3	188545164	LPP	Open sea	0.0370795	0.00825089	0.000007043307	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0624766	0.0139041	0.000007063183	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	FCER2 protein levels (SeqId = 3291-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FCER2 protein levels (SeqId = 3291-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Low affinity immunoglobulin epsilon Fc receptor	774	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.87	0.194	0.0000071	None	Gadd-DA_fcer2_protein_levels__seqid___3291-30__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	0.0370524	0.0082509	0.000007152929	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0370465	0.0082509	0.000007177053	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0370448	0.0082509	0.000007183764	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	KLK8 protein levels (SeqId = 2834-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLK8 protein levels (SeqId = 2834-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kallikrein-8	774	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.994	0.221	0.0000072	None	Gadd-DA_klk8_protein_levels__seqid___2834-54__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GPX7 protein levels (SeqId = 8345-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GPX7 protein levels (SeqId = 8345-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione peroxidase 7	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000072	None	Gadd-DA_gpx7_protein_levels__seqid___8345-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	OAZ1 protein levels (SeqId = 9893-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	OAZ1 protein levels (SeqId = 9893-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ornithine decarboxylase antizyme 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000072	None	Gadd-DA_oaz1_protein_levels__seqid___9893-27__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.048007	0.010694	0.000007204799	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0465705	0.0103749	0.000007217834	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.0370355	0.00825091	0.000007221712	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0370348	0.00825091	0.000007224973	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.048174	0.0107343	0.000007249843	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0370246	0.00825091	0.000007266863	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0415761	0.0092653	0.000007268339	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	STIP1 protein levels (SeqId = 5489-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STIP1 protein levels (SeqId = 5489-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Stress-induced-phosphoprotein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000073	None	Gadd-DA_stip1_protein_levels__seqid___5489-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	G3BP2 protein levels (SeqId = 9831-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	G3BP2 protein levels (SeqId = 9831-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras GTPase-activating protein-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000073	None	Gadd-DA_g3bp2_protein_levels__seqid___9831-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPS27A protein levels (SeqId = 2846-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPS27A protein levels (SeqId = 2846-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-40S ribosomal protein S27a	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000073	None	Gadd-DA_rps27a_protein_levels__seqid___2846-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAD1 protein levels (SeqId = 12670-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAD1 protein levels (SeqId = 12670-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cell cycle checkpoint protein RAD1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000073	None	Gadd-DA_rad1_protein_levels__seqid___12670-15__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.189229	0.042184	0.000007311163	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0369977	0.00825092	0.000007378665	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0369972	0.00825092	0.000007380808	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GP6 protein levels (SeqId = 3194-36)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GP6 protein levels (SeqId = 3194-36)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet glycoprotein VI	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000074	None	Gadd-DA_gp6_protein_levels__seqid___3194-36__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BTK protein levels (SeqId = 19202-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BTK protein levels (SeqId = 19202-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase BTK	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000074	None	Gadd-DA_btk_protein_levels__seqid___19202-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNTB1 protein levels (SeqId = 9078-207)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNTB1 protein levels (SeqId = 9078-207)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-1-syntrophin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000074	None	Gadd-DA_sntb1_protein_levels__seqid___9078-207__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDGFD protein levels (SeqId = 9341-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDGFD protein levels (SeqId = 9341-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet-derived growth factor D	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000074	None	Gadd-DA_pdgfd_protein_levels__seqid___9341-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF16 protein levels (SeqId = 4393-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF16 protein levels (SeqId = 4393-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 16	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000074	None	Gadd-DA_fgf16_protein_levels__seqid___4393-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0369746	0.00825093	0.000007476213	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	WSCD2 protein levels (SeqId = 6274-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	WSCD2 protein levels (SeqId = 6274-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: WSC domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000075	None	Gadd-DA_wscd2_protein_levels__seqid___6274-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SUMO3 protein levels (SeqId = 14623-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUMO3 protein levels (SeqId = 14623-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Small ubiquitin-related modifier 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000075	None	Gadd-DA_sumo3_protein_levels__seqid___14623-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PABPC4 protein levels (SeqId = 12603-87)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PABPC4 protein levels (SeqId = 12603-87)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Polyadenylate-binding protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000075	None	Gadd-DA_pabpc4_protein_levels__seqid___12603-87__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IDH3G protein levels (SeqId = 19275-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IDH3G protein levels (SeqId = 19275-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000075	None	Gadd-DA_idh3g_protein_levels__seqid___19275-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NXF1 protein levels (SeqId = 12453-161)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NXF1 protein levels (SeqId = 12453-161)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear RNA export factor 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000075	None	Gadd-DA_nxf1_protein_levels__seqid___12453-161__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.170884	0.0381532	0.00000755153	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0369551	0.00825093	0.000007559412	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Lai CQ	-	27777315	2016-12-01	Postprandial lipemia	EFO_0007632	Replication	Table S2	Postprandial lipemia	DNA methylation	Age, sex, study centre and technical covariates	-	Beta values	Illumina HumanMethylation450	CD4+ T-cells	Postprandial lipemia measured using the area under the curve	326	1	48.8	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	18.76	4.12	0.00000757	-	27777315_postprandial_lipemia_replication
Gadd DA	Generation Scotland	35945220	31/07/2022	ZFAND1 protein levels (SeqId = 19173-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZFAND1 protein levels (SeqId = 19173-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AN1-type zinc finger protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000076	None	Gadd-DA_zfand1_protein_levels__seqid___19173-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APP protein levels (SeqId = 3171-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APP protein levels (SeqId = 3171-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Amyloid-beta precursor protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000076	None	Gadd-DA_app_protein_levels__seqid___3171-57__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0373019	0.00833063	0.000007602888	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	0.0392928	0.00877636	0.000007622804	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0442497	0.00988814	0.000007697591	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	SPOCK1 protein levels (SeqId = 5490-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPOCK1 protein levels (SeqId = 5490-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Testican-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000077	None	Gadd-DA_spock1_protein_levels__seqid___5490-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CILP protein levels (SeqId = 5717-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CILP protein levels (SeqId = 5717-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cartilage intermediate layer protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000077	None	Gadd-DA_cilp_protein_levels__seqid___5717-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSP90AA1 protein levels (SeqId = 2625-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSP90AA1 protein levels (SeqId = 2625-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heat shock protein HSP 90-alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000077	None	Gadd-DA_hsp90aa1_protein_levels__seqid___2625-53__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.0369209	0.00825094	0.000007707618	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q16610	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q16610	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.049505	0.0110666	0.000007757804	Q16610	41361833_Josephine_Robertson_Q16610_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0619286	0.0138448	0.000007768721	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	AKT2 protein levels (SeqId = 5360-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AKT2 protein levels (SeqId = 5360-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: RAC-beta serine/threonine-protein kinase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000078	None	Gadd-DA_akt2_protein_levels__seqid___5360-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PIP4K2A protein levels (SeqId = 12697-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIP4K2A protein levels (SeqId = 12697-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000078	None	Gadd-DA_pip4k2a_protein_levels__seqid___12697-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACP1 protein levels (SeqId = 3858-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACP1 protein levels (SeqId = 3858-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Low molecular weight phosphotyrosine protein phosphatase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.0000078	None	Gadd-DA_acp1_protein_levels__seqid___3858-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJC18 protein levels (SeqId = 8033-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJC18 protein levels (SeqId = 8033-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily C member 18	774	1	Adults (18-65 years)	Both	European	cg18896634	chr3:188191833	3	188191833	LPP	Open sea	-0.6	0.135	0.0000078	None	Gadd-DA_dnajc18_protein_levels__seqid___8033-1__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	0.178746	0.0399737	0.000007811062	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.03689	0.00825095	0.000007843721	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0368879	0.00825095	0.000007853083	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NAP1L4 protein levels (SeqId = 19188-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAP1L4 protein levels (SeqId = 19188-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nucleosome assembly protein 1-like 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000079	None	Gadd-DA_nap1l4_protein_levels__seqid___19188-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTK1 protein levels (SeqId = 13474-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTK1 protein levels (SeqId = 13474-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase kappa 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000079	None	Gadd-DA_gstk1_protein_levels__seqid___13474-40__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.059558	0.0133277	0.000007927196	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0415824	0.00930529	0.000007929368	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07196133	chr3:188439649	3	188439649	LPP	Open sea	0.0368577	0.00825096	0.000007988789	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2V2 protein levels (SeqId = 18165-181)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2V2 protein levels (SeqId = 18165-181)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 variant 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.000008	None	Gadd-DA_ube2v2_protein_levels__seqid___18165-181__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MRE11A protein levels (SeqId = 11319-106)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MRE11A protein levels (SeqId = 11319-106)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Double-strand break repair protein MRE11	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.94	0.209	0.000008	None	Gadd-DA_mre11a_protein_levels__seqid___11319-106__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0368541	0.00825096	0.000008005017	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	-0.0407256	0.00911846	0.00000801857	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0531061	0.0118905	0.000008018929	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	-0.138747	0.0310768	0.000008071281	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0373688	0.00836958	0.000008072674	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.0368357	0.00825097	0.000008088837	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPPA protein levels (SeqId = 4148-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPPA protein levels (SeqId = 4148-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pappalysin-1	774	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.66	0.148	0.0000081	None	Gadd-DA_pappa_protein_levels__seqid___4148-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NEK7 protein levels (SeqId = 12703-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NEK7 protein levels (SeqId = 12703-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase Nek7	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000081	None	Gadd-DA_nek7_protein_levels__seqid___12703-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ISOC1 protein levels (SeqId = 9816-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ISOC1 protein levels (SeqId = 9816-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Isochorismatase domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000081	None	Gadd-DA_isoc1_protein_levels__seqid___9816-37__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0368279	0.00825097	0.000008124836	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0441221	0.00988651	0.000008147508	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0368214	0.00825097	0.000008154657	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	IGLL1 protein levels (SeqId = 6485-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IGLL1 protein levels (SeqId = 6485-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin lambda-like polypeptide 1	774	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	0.94	0.21	0.0000082	None	Gadd-DA_igll1_protein_levels__seqid___6485-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AGFG1 protein levels (SeqId = 11681-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AGFG1 protein levels (SeqId = 11681-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Arf-GAP domain and FG repeat-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000082	None	Gadd-DA_agfg1_protein_levels__seqid___11681-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJA4 protein levels (SeqId = 9744-139)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJA4 protein levels (SeqId = 9744-139)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily A member 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000082	None	Gadd-DA_dnaja4_protein_levels__seqid___9744-139__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF4E protein levels (SeqId = 19263-147)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF4E protein levels (SeqId = 19263-147)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 4E	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000082	None	Gadd-DA_eif4e_protein_levels__seqid___19263-147__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0480947	0.0107814	0.000008222798	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0368001	0.00825098	0.000008253481	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0453005	0.0101579	0.000008271446	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0367834	0.00825098	0.000008331689	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ALDOA protein levels (SeqId = 5864-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALDOA protein levels (SeqId = 5864-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fructose-bisphosphate aldolase A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000084	None	Gadd-DA_aldoa_protein_levels__seqid___5864-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	L3MBTL2 protein levels (SeqId = 12708-91)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	L3MBTL2 protein levels (SeqId = 12708-91)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lethal(3)malignant brain tumor-like protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000084	None	Gadd-DA_l3mbtl2_protein_levels__seqid___12708-91__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.045094	0.0101222	0.000008453722	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	TREML2 protein levels (SeqId = 5736-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TREML2 protein levels (SeqId = 5736-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Trem-like transcript 2 protein	774	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	1.07	0.241	0.0000085	None	Gadd-DA_treml2_protein_levels__seqid___5736-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0367432	0.008251	0.000008523183	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.0379233	0.00851678	0.000008539622	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0367347	0.008251	0.000008563998	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0416806	0.00936213	0.000008568684	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	-0.0367275	0.008251	0.000008598961	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02579706	chr3:187960622	3	187960622	LPP	Open sea	-0.0013	0.00028	0.0000086	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	HADH protein levels (SeqId = 17739-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HADH protein levels (SeqId = 17739-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000086	None	Gadd-DA_hadh_protein_levels__seqid___17739-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAFG protein levels (SeqId = 19281-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAFG protein levels (SeqId = 19281-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription factor MafG	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000086	None	Gadd-DA_mafg_protein_levels__seqid___19281-86__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0432686	0.00972288	0.000008642987	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	0.036716	0.008251	0.000008654865	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	BRD4 protein levels (SeqId = 10043-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BRD4 protein levels (SeqId = 10043-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bromodomain-containing protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000087	None	Gadd-DA_brd4_protein_levels__seqid___10043-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDPK1 protein levels (SeqId = 4460-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDPK1 protein levels (SeqId = 4460-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 3-phosphoinositide-dependent protein kinase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000087	None	Gadd-DA_pdpk1_protein_levels__seqid___4460-8__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.073072	0.0164254	0.000008701877	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	-0.0376443	0.00846267	0.000008719841	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	1.12036	0.252	0.00000872	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0478706	0.0107623	0.000008731402	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0366955	0.00825101	0.000008755889	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	ALKBH3 protein levels (SeqId = 18401-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALKBH3 protein levels (SeqId = 18401-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000088	None	Gadd-DA_alkbh3_protein_levels__seqid___18401-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PMVK protein levels (SeqId = 12450-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PMVK protein levels (SeqId = 12450-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphomevalonate kinase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000088	None	Gadd-DA_pmvk_protein_levels__seqid___12450-42__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0366769	0.00825102	0.000008848074	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	APLP2 protein levels (SeqId = 10627-87)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APLP2 protein levels (SeqId = 10627-87)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Amyloid-like protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.208	0.0000089	None	Gadd-DA_aplp2_protein_levels__seqid___10627-87__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NMRAL1 protein levels (SeqId = 13988-67)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NMRAL1 protein levels (SeqId = 13988-67)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NmrA-like family domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000089	None	Gadd-DA_nmral1_protein_levels__seqid___13988-67__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PTK2B protein levels (SeqId = 8918-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTK2B protein levels (SeqId = 8918-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein-tyrosine kinase 2-beta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000089	None	Gadd-DA_ptk2b_protein_levels__seqid___8918-64__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0366604	0.00825102	0.00000893066	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0366557	0.00825102	0.000008954561	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.166035	0.0373797	0.000008970918	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.147264	0.0331535	0.000008972298	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0366387	0.00825103	0.000009040552	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0477943	0.0107647	0.000009064986	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0366306	0.00825103	0.000009082085	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	0.0366272	0.00825103	0.000009099521	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDH2 protein levels (SeqId = 15534-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDH2 protein levels (SeqId = 15534-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Malate dehydrogenase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000091	None	Gadd-DA_mdh2_protein_levels__seqid___15534-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDC42BPB protein levels (SeqId = 3629-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDC42BPB protein levels (SeqId = 3629-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase MRCK beta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000091	None	Gadd-DA_cdc42bpb_protein_levels__seqid___3629-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAC3 protein levels (SeqId = 16769-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAC3 protein levels (SeqId = 16769-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related C3 botulinum toxin substrate 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000091	None	Gadd-DA_rac3_protein_levels__seqid___16769-20__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0475646	0.0107162	0.000009121271	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0366163	0.00825103	0.000009155286	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	1.6	0.357	0.0000092	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ASNA1 protein levels (SeqId = 13620-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASNA1 protein levels (SeqId = 13620-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ATPase ASNA1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000092	None	Gadd-DA_asna1_protein_levels__seqid___13620-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SUGT1 protein levels (SeqId = 17818-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUGT1 protein levels (SeqId = 17818-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein SGT1 homolog	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000092	None	Gadd-DA_sugt1_protein_levels__seqid___17818-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SMAP1 protein levels (SeqId = 11649-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMAP1 protein levels (SeqId = 11649-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Stromal membrane-associated protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000092	None	Gadd-DA_smap1_protein_levels__seqid___11649-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0366023	0.00825104	0.000009227686	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0366021	0.00825104	0.00000922875	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0366005	0.00825104	0.000009237267	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0365985	0.00825104	0.00000924757	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0365951	0.00825104	0.000009265007	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TSG101 protein levels (SeqId = 13044-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TSG101 protein levels (SeqId = 13044-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor susceptibility gene 101 protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.0000093	None	Gadd-DA_tsg101_protein_levels__seqid___13044-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0428791	0.00967051	0.000009317157	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0420941	0.00949462	0.000009340239	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	0.0386518	0.00872024	0.000009385873	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01356198	chr3:187929513	3	187929513	LPP	Open sea	0.0017	None	0.0000094	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	SYT11 protein levels (SeqId = 7089-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SYT11 protein levels (SeqId = 7089-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Synaptotagmin-11	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000094	None	Gadd-DA_syt11_protein_levels__seqid___7089-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKCB protein levels (SeqId = 5475-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKCB protein levels (SeqId = 5475-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein kinase C beta type	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000094	None	Gadd-DA_prkcb_protein_levels__seqid___5475-10__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.14727	0.0332308	0.000009402493	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0404384	0.00912724	0.000009468706	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.058647	0.0132371	0.000009468804	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	GPCPD1 protein levels (SeqId = 12786-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GPCPD1 protein levels (SeqId = 12786-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycerophosphocholine phosphodiesterase GPCPD1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000095	None	Gadd-DA_gpcpd1_protein_levels__seqid___12786-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BAG1 protein levels (SeqId = 17195-43)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BAG1 protein levels (SeqId = 17195-43)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: BAG family molecular chaperone regulator 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000095	None	Gadd-DA_bag1_protein_levels__seqid___17195-43__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	-0.0384156	0.00867527	0.000009572005	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0365322	0.00825106	0.000009598788	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18603679	chr3:188247767	3	188247767	LPP	Open sea	0.0059	None	0.0000096	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	SPG20 protein levels (SeqId = 11161-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPG20 protein levels (SeqId = 11161-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Spartin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000096	None	Gadd-DA_spg20_protein_levels__seqid___11161-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FKBP4 protein levels (SeqId = 17722-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FKBP4 protein levels (SeqId = 17722-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase FKBP4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000096	None	Gadd-DA_fkbp4_protein_levels__seqid___17722-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0365259	0.00825106	0.00000963274	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0410154	0.00926599	0.000009649123	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.158372	0.0357807	0.000009649912	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0787399	0.0177929	0.000009698257	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	PNKP protein levels (SeqId = 13657-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PNKP protein levels (SeqId = 13657-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bifunctional polynucleotide phosphatase/kinase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000097	None	Gadd-DA_pnkp_protein_levels__seqid___13657-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARL6IP5 protein levels (SeqId = 13503-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARL6IP5 protein levels (SeqId = 13503-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PRA1 family protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.93	0.209	0.0000097	None	Gadd-DA_arl6ip5_protein_levels__seqid___13503-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KIAA1279 protein levels (SeqId = 12956-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIAA1279 protein levels (SeqId = 12956-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: KIF1-binding protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.0000097	None	Gadd-DA_kiaa1279_protein_levels__seqid___12956-40__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0413578	0.0093487	0.000009763032	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0365019	0.00825107	0.000009763137	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0364973	0.00825107	0.000009788739	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	POGLUT1 protein levels (SeqId = 6467-65)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	POGLUT1 protein levels (SeqId = 6467-65)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein O-glucosyltransferase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.0000098	None	Gadd-DA_poglut1_protein_levels__seqid___6467-65__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDX6 protein levels (SeqId = 12869-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDX6 protein levels (SeqId = 12869-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable ATP-dependent RNA helicase DDX6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.0000098	None	Gadd-DA_ddx6_protein_levels__seqid___12869-68__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	0.14303	0.0323422	0.000009820169	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0364915	0.00825107	0.000009820332	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0441322	0.00998103	0.000009867261	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.061051	0.013809	0.00000989136	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	UFM1 protein levels (SeqId = 3836-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UFM1 protein levels (SeqId = 3836-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-fold modifier 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.0000099	None	Gadd-DA_ufm1_protein_levels__seqid___3836-51__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.0418291	0.0094621	0.000009908758	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0391934	0.00886856	0.000009969867	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	ANXA7 protein levels (SeqId = 14203-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANXA7 protein levels (SeqId = 14203-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Annexin A7	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.00001	None	Gadd-DA_anxa7_protein_levels__seqid___14203-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NDUFA5 protein levels (SeqId = 19200-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NDUFA5 protein levels (SeqId = 19200-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.923	0.209	0.00001	None	Gadd-DA_ndufa5_protein_levels__seqid___19200-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZP4 protein levels (SeqId = 7766-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZP4 protein levels (SeqId = 7766-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Zona pellucida sperm-binding protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.00001	None	Gadd-DA_zp4_protein_levels__seqid___7766-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DARS2 protein levels (SeqId = 12395-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DARS2 protein levels (SeqId = 12395-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aspartate--tRNA ligase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.00001	None	Gadd-DA_dars2_protein_levels__seqid___12395-86__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HEXIM2 protein levels (SeqId = 14205-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HEXIM2 protein levels (SeqId = 14205-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein HEXIM2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.00001	None	Gadd-DA_hexim2_protein_levels__seqid___14205-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDXP protein levels (SeqId = 3897-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDXP protein levels (SeqId = 3897-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pyridoxal phosphate phosphatase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.00001	None	Gadd-DA_pdxp_protein_levels__seqid___3897-61__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21101580	chr3:188545164	3	188545164	LPP	Open sea	0.0364508	0.00825108	0.00001004706	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0430359	0.00974347	0.00001008468	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	0.0364363	0.00825109	0.00001012936	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0395753	0.00896207	0.00001013245	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0364336	0.00825109	0.00001014445	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0364239	0.00825109	0.00001019982	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0475417	0.0107727	0.00001026044	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	0.0364051	0.0082511	0.00001030767	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0411222	0.00932238	0.00001035648	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0363718	0.00825111	0.00001050163	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.122441	0.0277806	0.00001052129	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	0.155166	0.0352169	0.00001059291	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.13878	0.0315069	0.00001065419	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.036344	0.00825112	0.00001066627	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.154277	0.0350381	0.00001073087	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0363331	0.00825112	0.00001073168	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23235460	chr3:187871625	3	187871625	LPP	Island	0.036326	0.00825112	0.0000107738	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0363188	0.00825112	0.00001081758	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	0.0357929	0.00813364	0.00001087117	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	-0.0382293	0.00868831	0.00001089713	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00819081	chr3:188103477	3	188103477	LPP	Open sea	0.185395	0.0421397	0.00001091328	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	-0.0363026	0.00825113	0.00001091611	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0363016	0.00825113	0.0000109221	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0362908	0.00825113	0.00001098783	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMA protein levels (SeqId = 3440-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMA protein levels (SeqId = 3440-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme A	774	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.79	0.18	0.000011	None	Gadd-DA_gzma_protein_levels__seqid___3440-7__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.038	0.00861	0.000011	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ASCC1 protein levels (SeqId = 10647-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASCC1 protein levels (SeqId = 10647-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Activating signal cointegrator 1 complex subunit 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_ascc1_protein_levels__seqid___10647-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HMHA1 protein levels (SeqId = 13544-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HMHA1 protein levels (SeqId = 13544-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 45	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_hmha1_protein_levels__seqid___13544-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CDC37 protein levels (SeqId = 3879-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDC37 protein levels (SeqId = 3879-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hsp90 co-chaperone Cdc37	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_cdc37_protein_levels__seqid___3879-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF7 protein levels (SeqId = 4487-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF7 protein levels (SeqId = 4487-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 7	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_fgf7_protein_levels__seqid___4487-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB2 protein levels (SeqId = 11438-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB2 protein levels (SeqId = 11438-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_dnajb2_protein_levels__seqid___11438-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COLGALT1 protein levels (SeqId = 5638-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COLGALT1 protein levels (SeqId = 5638-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Procollagen galactosyltransferase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_colgalt1_protein_levels__seqid___5638-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PTP4A2 protein levels (SeqId = 11699-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTP4A2 protein levels (SeqId = 11699-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein tyrosine phosphatase type IVA 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_ptp4a2_protein_levels__seqid___11699-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB3D protein levels (SeqId = 19379-154)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB3D protein levels (SeqId = 19379-154)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-3D	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_rab3d_protein_levels__seqid___19379-154__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HRAS protein levels (SeqId = 18900-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HRAS protein levels (SeqId = 18900-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GTPase HRas	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_hras_protein_levels__seqid___18900-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFSF14 protein levels (SeqId = 5355-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFSF14 protein levels (SeqId = 5355-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor ligand superfamily member 14	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_tnfsf14_protein_levels__seqid___5355-69__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MTHFS protein levels (SeqId = 14107-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MTHFS protein levels (SeqId = 14107-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 5-formyltetrahydrofolate cyclo-ligase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_mthfs_protein_levels__seqid___14107-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRPSAP1 protein levels (SeqId = 9478-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRPSAP1 protein levels (SeqId = 9478-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphoribosyl pyrophosphate synthase-associated protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_prpsap1_protein_levels__seqid___9478-69__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CARS protein levels (SeqId = 14098-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CARS protein levels (SeqId = 14098-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cysteine--tRNA ligase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_cars_protein_levels__seqid___14098-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	REXO2 protein levels (SeqId = 13590-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	REXO2 protein levels (SeqId = 13590-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Oligoribonuclease, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_rexo2_protein_levels__seqid___13590-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ERP44 protein levels (SeqId = 6064-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ERP44 protein levels (SeqId = 6064-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endoplasmic reticulum resident protein 44	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000011	None	Gadd-DA_erp44_protein_levels__seqid___6064-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF8 protein levels (SeqId = 4394-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF8 protein levels (SeqId = 4394-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 8	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.921	0.209	0.000011	None	Gadd-DA_fgf8_protein_levels__seqid___4394-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMA protein levels (SeqId = 3440-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMA protein levels (SeqId = 3440-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme A	774	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.59	0.135	0.000011	None	Gadd-DA_gzma_protein_levels__seqid___3440-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMK protein levels (SeqId = 9545-156)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMK protein levels (SeqId = 9545-156)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme K	774	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.59	0.135	0.000011	None	Gadd-DA_gzmk_protein_levels__seqid___9545-156__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23493553	chr3:188055123	3	188055123	LPP	Open sea	0.0362836	0.00825113	0.0000110324	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	0.0362802	0.00825114	0.00001105352	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0362649	0.00825114	0.00001114828	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0362636	0.00825114	0.00001115601	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0714272	0.0162547	0.0000111942	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0397208	0.00904108	0.00001123912	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0362451	0.00825115	0.00001127159	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0362451	0.00825115	0.0000112717	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0362438	0.00825115	0.00001128016	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.0642533	0.0146281	0.00001128663	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0362427	0.00825115	0.00001128681	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0362351	0.00825115	0.00001133492	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0362248	0.00825115	0.00001140036	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0647863	0.0147625	0.00001148873	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.036204	0.00825116	0.000011533	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P23142	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P23142	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0382738	0.00872293	0.00001153413	P23142	41361833_Josephine_Robertson_P23142_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0624701	0.0142459	0.00001167223	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0519428	0.0118455	0.00001167877	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0396824	0.00905033	0.00001169904	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0361713	0.00825117	0.00001174499	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0505284	0.0115265	0.00001175119	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	-0.0380709	0.00868576	0.00001177945	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	-0.0361639	0.00825117	0.00001179333	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.0366188	0.00835832	0.00001188876	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0361379	0.00825118	0.00001196555	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Lu X	<U+00A0>Lifelines DEEP	32916427	2020-09-09	MBzP	None	None	ST14	DNA methylation	MBzP	Age, Sex, body mass index, cell composition (reference based), batch effects	Beta Values	ng/24h	Illumina HumanMethylation450	Whole blood	The trait is a phthalate metabolite	622	1	Adults	Both	European	cg04423294	chr3:188479059	3	188479059	LPP	Open sea	0.0112	0.00256	0.000012	None	32916427_Lu-X_mbzp
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20893542	chr3:187929286	3	187929286	LPP	Open sea	-0.00844	0.00188	0.000012	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg22209756	chr3:187901412	3	187901412	LPP	Open sea	0.036	0.00813	0.000012	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	TPM4 protein levels (SeqId = 9863-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TPM4 protein levels (SeqId = 9863-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tropomyosin alpha-4 chain	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000012	None	Gadd-DA_tpm4_protein_levels__seqid___9863-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AHCYL1 protein levels (SeqId = 12652-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AHCYL1 protein levels (SeqId = 12652-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: S-adenosylhomocysteine hydrolase-like protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000012	None	Gadd-DA_ahcyl1_protein_levels__seqid___12652-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HDGF protein levels (SeqId = 16758-96)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDGF protein levels (SeqId = 16758-96)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatoma-derived growth factor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000012	None	Gadd-DA_hdgf_protein_levels__seqid___16758-96__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NUDT2 protein levels (SeqId = 16583-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUDT2 protein levels (SeqId = 16583-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000012	None	Gadd-DA_nudt2_protein_levels__seqid___16583-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	USP14 protein levels (SeqId = 19189-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	USP14 protein levels (SeqId = 19189-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin carboxyl-terminal hydrolase 14	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000012	None	Gadd-DA_usp14_protein_levels__seqid___19189-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPBP protein levels (SeqId = 4544-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPBP protein levels (SeqId = 4544-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet basic protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000012	None	Gadd-DA_ppbp_protein_levels__seqid___4544-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSIP1 protein levels (SeqId = 17176-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSIP1 protein levels (SeqId = 17176-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PC4 and SFRS1-interacting protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000012	None	Gadd-DA_psip1_protein_levels__seqid___17176-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADAM9 protein levels (SeqId = 3795-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADAM9 protein levels (SeqId = 3795-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Disintegrin and metalloproteinase domain-containing protein 9	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000012	None	Gadd-DA_adam9_protein_levels__seqid___3795-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COPS2 protein levels (SeqId = 14029-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COPS2 protein levels (SeqId = 14029-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: COP9 signalosome complex subunit 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000012	None	Gadd-DA_cops2_protein_levels__seqid___14029-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NMT2 protein levels (SeqId = 17821-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NMT2 protein levels (SeqId = 17821-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycylpeptide N-tetradecanoyltransferase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000012	None	Gadd-DA_nmt2_protein_levels__seqid___17821-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DYNLT3 protein levels (SeqId = 12867-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DYNLT3 protein levels (SeqId = 12867-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dynein light chain Tctex-type 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.21	0.000012	None	Gadd-DA_dynlt3_protein_levels__seqid___12867-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHC1 protein levels (SeqId = 16043-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHC1 protein levels (SeqId = 16043-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SHC-transforming protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000012	None	Gadd-DA_shc1_protein_levels__seqid___16043-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PFKM protein levels (SeqId = 17384-110)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PFKM protein levels (SeqId = 17384-110)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ATP-dependent 6-phosphofructokinase, muscle type	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000012	None	Gadd-DA_pfkm_protein_levels__seqid___17384-110__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRPEL1 protein levels (SeqId = 7113-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRPEL1 protein levels (SeqId = 7113-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GrpE protein homolog 1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000012	None	Gadd-DA_grpel1_protein_levels__seqid___7113-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLXDC2 protein levels (SeqId = 11342-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLXDC2 protein levels (SeqId = 11342-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Plexin domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000012	None	Gadd-DA_plxdc2_protein_levels__seqid___11342-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AIF1 protein levels (SeqId = 2849-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AIF1 protein levels (SeqId = 2849-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Allograft inflammatory factor 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.92	0.209	0.000012	None	Gadd-DA_aif1_protein_levels__seqid___2849-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0667083	0.0152415	0.00001212977	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.148454	0.0339267	0.00001216927	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	0.0354202	0.00809531	0.00001220478	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0425815	0.00973324	0.00001223515	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0360968	0.00825119	0.00001224163	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0360928	0.00825119	0.00001226929	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0360748	0.0082512	0.00001239252	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0442341	0.0101175	0.00001239449	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.0430796	0.00985946	0.00001254636	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.159743	0.0365634	0.00001255737	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0527722	0.0120788	0.00001256815	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0360439	0.00825121	0.00001260686	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0471443	0.0107946	0.00001266057	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.0360357	0.00825121	0.00001266399	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0006223	0.0001419	0.0000127	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0478089	0.0109521	0.00001278337	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0360084	0.00825122	0.00001285692	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0359892	0.00825122	0.00001299467	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.065	0.0149	0.000013	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ATF6B protein levels (SeqId = 11387-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ATF6B protein levels (SeqId = 11387-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cyclic AMP-dependent transcription factor ATF-6 beta	774	1	Adults (18-65 years)	Both	European	cg05299185	chr3:187872455	3	187872455	LPP	South shore	-0.95	0.218	0.000013	None	Gadd-DA_atf6b_protein_levels__seqid___11387-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMEM190 protein levels (SeqId = 10442-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMEM190 protein levels (SeqId = 10442-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transmembrane protein 190	774	1	Adults (18-65 years)	Both	European	cg06070275	chr3:187930207	3	187930207	LPP	Open sea	-0.761	0.175	0.000013	None	Gadd-DA_tmem190_protein_levels__seqid___10442-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HDGF protein levels (SeqId = 8953-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDGF protein levels (SeqId = 8953-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatoma-derived growth factor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000013	None	Gadd-DA_hdgf_protein_levels__seqid___8953-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RPL12 protein levels (SeqId = 19183-164)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RPL12 protein levels (SeqId = 19183-164)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 60S ribosomal protein L12	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000013	None	Gadd-DA_rpl12_protein_levels__seqid___19183-164__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PIK3CA protein levels (SeqId = 3390-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PIK3CA protein levels (SeqId = 3390-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform|Phosphatidylinositol 3-kinase regulatory subunit alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000013	None	Gadd-DA_pik3ca_protein_levels__seqid___3390-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANXA11 protein levels (SeqId = 17513-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANXA11 protein levels (SeqId = 17513-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Annexin A11	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000013	None	Gadd-DA_anxa11_protein_levels__seqid___17513-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL2RG protein levels (SeqId = 2634-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL2RG protein levels (SeqId = 2634-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytokine receptor common subunit gamma	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000013	None	Gadd-DA_il2rg_protein_levels__seqid___2634-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRDX3 protein levels (SeqId = 8358-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRDX3 protein levels (SeqId = 8358-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin-dependent peroxide reductase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000013	None	Gadd-DA_prdx3_protein_levels__seqid___8358-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GPN1 protein levels (SeqId = 16599-38)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GPN1 protein levels (SeqId = 16599-38)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GPN-loop GTPase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000013	None	Gadd-DA_gpn1_protein_levels__seqid___16599-38__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IFNL1 protein levels (SeqId = 4396-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFNL1 protein levels (SeqId = 4396-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon lambda-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000013	None	Gadd-DA_ifnl1_protein_levels__seqid___4396-54__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAK4 protein levels (SeqId = 13719-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAK4 protein levels (SeqId = 13719-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase PAK 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000013	None	Gadd-DA_pak4_protein_levels__seqid___13719-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDHX protein levels (SeqId = 18319-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDHX protein levels (SeqId = 18319-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pyruvate dehydrogenase protein X component, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000013	None	Gadd-DA_pdhx_protein_levels__seqid___18319-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0359837	0.00825122	0.0000130346	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0359826	0.00825122	0.00001304226	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0409286	0.00938729	0.00001309491	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.0359704	0.00825123	0.00001313049	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0481312	0.0110414	0.00001314478	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0359673	0.00825123	0.00001315326	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0514334	0.0118002	0.00001317318	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.035964	0.00825123	0.00001317706	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	0.0359491	0.00825123	0.00001328672	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0359452	0.00825124	0.00001331561	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0511775	0.0117486	0.00001333263	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0389594	0.00894425	0.00001334797	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.064826	0.0148831	0.00001335548	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0403415	0.00926305	0.00001339119	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0600491	0.0137887	0.00001340114	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0558585	0.0128281	0.00001343496	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.077891	0.0178886	0.00001344454	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0359249	0.00825124	0.00001346547	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.035914	0.00825125	0.00001354697	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0359092	0.00825125	0.00001358277	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0595417	0.0136819	0.00001358959	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0359075	0.00825125	0.00001359589	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0388831	0.00893516	0.00001360032	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0359041	0.00825125	0.00001362119	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0358925	0.00825125	0.00001370922	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	-0.0479213	0.0110184	0.00001375661	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0464215	0.0106736	0.00001375674	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.0358856	0.00825125	0.00001376131	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0389386	0.00895365	0.00001377365	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0358745	0.00825126	0.00001384584	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	-0.0365348	0.0084033	0.00001385142	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17125927	chr3:187924031	3	187924031	LPP	Open sea	-0.0358715	0.00825126	0.00001386885	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0358683	0.00825126	0.00001389362	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	-0.0358592	0.00825126	0.00001396334	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	0.0043	0.00098	0.000014	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.027	0.00618	0.000014	None	Robert-F-Hillary_Incident_COPD_Basic_model
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	1.5	0.355	0.000014	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	TMEFF1 protein levels (SeqId = 15641-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMEFF1 protein levels (SeqId = 15641-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tomoregulin-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_tmeff1_protein_levels__seqid___15641-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SYF2 protein levels (SeqId = 19438-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SYF2 protein levels (SeqId = 19438-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pre-mRNA-splicing factor SYF2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_syf2_protein_levels__seqid___19438-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNUPN protein levels (SeqId = 17765-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNUPN protein levels (SeqId = 17765-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Snurportin-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_snupn_protein_levels__seqid___17765-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DKK2 protein levels (SeqId = 15678-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DKK2 protein levels (SeqId = 15678-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dickkopf-related protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_dkk2_protein_levels__seqid___15678-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RTN4IP1 protein levels (SeqId = 18180-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RTN4IP1 protein levels (SeqId = 18180-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Reticulon-4-interacting protein 1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_rtn4ip1_protein_levels__seqid___18180-58__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HDHD2 protein levels (SeqId = 13472-35)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDHD2 protein levels (SeqId = 13472-35)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Haloacid dehalogenase-like hydrolase domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_hdhd2_protein_levels__seqid___13472-35__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM177A1 protein levels (SeqId = 8039-41)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM177A1 protein levels (SeqId = 8039-41)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM177A1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_fam177a1_protein_levels__seqid___8039-41__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PCNP protein levels (SeqId = 17769-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PCNP protein levels (SeqId = 17769-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PEST proteolytic signal-containing nuclear protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_pcnp_protein_levels__seqid___17769-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APRT protein levels (SeqId = 10088-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APRT protein levels (SeqId = 10088-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adenine phosphoribosyltransferase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_aprt_protein_levels__seqid___10088-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKCSH protein levels (SeqId = 5687-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKCSH protein levels (SeqId = 5687-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glucosidase 2 subunit beta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_prkcsh_protein_levels__seqid___5687-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SERPINE2 protein levels (SeqId = 19154-41)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SERPINE2 protein levels (SeqId = 19154-41)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glia-derived nexin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_serpine2_protein_levels__seqid___19154-41__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NAPG protein levels (SeqId = 17773-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAPG protein levels (SeqId = 17773-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-soluble NSF attachment protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_napg_protein_levels__seqid___17773-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HSP90B1 protein levels (SeqId = 6393-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HSP90B1 protein levels (SeqId = 6393-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Endoplasmin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_hsp90b1_protein_levels__seqid___6393-63__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HINT2 protein levels (SeqId = 5612-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HINT2 protein levels (SeqId = 5612-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histidine triad nucleotide-binding protein 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_hint2_protein_levels__seqid___5612-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAWR protein levels (SeqId = 9565-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAWR protein levels (SeqId = 9565-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PRKC apoptosis WT1 regulator protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_pawr_protein_levels__seqid___9565-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DLX4 protein levels (SeqId = 11910-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DLX4 protein levels (SeqId = 11910-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Homeobox protein DLX-4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000014	None	Gadd-DA_dlx4_protein_levels__seqid___11910-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IMPA1 protein levels (SeqId = 17796-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IMPA1 protein levels (SeqId = 17796-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inositol monophosphatase 1	774	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	1.22	0.28	0.000014	None	Gadd-DA_impa1_protein_levels__seqid___17796-15__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I0	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6I0	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0426007	0.00980462	0.00001402361	A0A075B6I0	41361833_Josephine_Robertson_A0A075B6I0_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.0358503	0.00825126	0.00001403227	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0376783	0.00867237	0.00001404438	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.0358481	0.00825126	0.00001404939	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0358468	0.00825126	0.00001405983	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0407949	0.0093903	0.00001406153	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0358331	0.00825127	0.00001416603	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	-0.199813	0.0460201	0.00001420911	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0358276	0.00825127	0.00001420949	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	-0.0358237	0.00825127	0.0000142395	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0358034	0.00825128	0.00001439995	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0480041	0.0110658	0.00001447094	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0357943	0.00825128	0.00001447253	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0393582	0.00907591	0.00001456996	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0392051	0.0090471	0.00001477723	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.0357555	0.00825129	0.00001478525	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0357493	0.00825129	0.00001483571	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0458723	0.0105935	0.00001499438	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.14	0.0319	0.000015	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26318252	chr3:188281073	3	188281073	LPP	Open sea	-0.0045	0.001	0.000015	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	TTC1 protein levels (SeqId = 9864-38)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TTC1 protein levels (SeqId = 9864-38)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tetratricopeptide repeat protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000015	None	Gadd-DA_ttc1_protein_levels__seqid___9864-38__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM162A protein levels (SeqId = 6531-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM162A protein levels (SeqId = 6531-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein FAM162A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000015	None	Gadd-DA_fam162a_protein_levels__seqid___6531-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CASP3 protein levels (SeqId = 3593-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASP3 protein levels (SeqId = 3593-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Caspase-3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000015	None	Gadd-DA_casp3_protein_levels__seqid___3593-72__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MFAP3L protein levels (SeqId = 8837-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MFAP3L protein levels (SeqId = 8837-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Microfibrillar-associated protein 3-like	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000015	None	Gadd-DA_mfap3l_protein_levels__seqid___8837-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NFKBIB protein levels (SeqId = 17387-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NFKBIB protein levels (SeqId = 17387-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NF-kappa-B inhibitor beta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000015	None	Gadd-DA_nfkbib_protein_levels__seqid___17387-27__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2F protein levels (SeqId = 18213-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2F protein levels (SeqId = 18213-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NEDD8-conjugating enzyme UBE2F	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000015	None	Gadd-DA_ube2f_protein_levels__seqid___18213-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJB6 protein levels (SeqId = 11606-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJB6 protein levels (SeqId = 11606-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily B member 6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000015	None	Gadd-DA_dnajb6_protein_levels__seqid___11606-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RFXAP protein levels (SeqId = 12726-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RFXAP protein levels (SeqId = 12726-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Regulatory factor X-associated protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000015	None	Gadd-DA_rfxap_protein_levels__seqid___12726-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBQLN2 protein levels (SeqId = 19121-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBQLN2 protein levels (SeqId = 19121-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquilin-2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.91	0.209	0.000015	None	Gadd-DA_ubqln2_protein_levels__seqid___19121-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0363229	0.0083905	0.00001507497	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.00056369	0.00012965	0.0000151	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0357123	0.0082513	0.00001514144	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.065795	0.0152048	0.00001519722	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0357031	0.00825131	0.00001521816	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0356847	0.00825131	0.00001537285	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0397539	0.00919288	0.00001539425	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg00819081	chr3:188103477	3	188103477	LPP	Open sea	0.176737	0.0408734	0.00001540285	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0426798	0.00987225	0.00001547939	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	0.0432601	0.0100065	0.00001547968	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	-0.0406775	0.00941163	0.00001556092	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0356548	0.00825132	0.00001562724	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	0.0360855	0.00835143	0.00001564347	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.038755	0.0089702	0.0000156761	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.0356463	0.00825132	0.00001570054	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0356335	0.00825133	0.00001581112	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0508128	0.0117666	0.00001582122	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11323106	chr3:188490680	3	188490680	LPP	Open sea	-0.0356276	0.00825133	0.00001586298	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.0356254	0.00825133	0.00001588161	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0415321	0.00962056	0.00001591925	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0601929	0.0139436	0.00001592937	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0385504	0.00893096	0.00001595712	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0602195	0.0139518	0.00001597433	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15131848	chr3:187875197	3	187875197	LPP	South shelf	-0.174764	0.040493	0.00001597808	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.025	0.00568	0.000016	None	Robert-F-Hillary_Incident_COPD_Basic_model
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-1.5	0.353	0.000016	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ADK protein levels (SeqId = 19207-119)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADK protein levels (SeqId = 19207-119)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adenosine kinase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000016	None	Gadd-DA_adk_protein_levels__seqid___19207-119__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SARS2 protein levels (SeqId = 12348-46)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SARS2 protein levels (SeqId = 12348-46)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine--tRNA ligase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000016	None	Gadd-DA_sars2_protein_levels__seqid___12348-46__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DKK1 protein levels (SeqId = 3535-84)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DKK1 protein levels (SeqId = 3535-84)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dickkopf-related protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000016	None	Gadd-DA_dkk1_protein_levels__seqid___3535-84__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADGRF1 protein levels (SeqId = 11243-90)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADGRF1 protein levels (SeqId = 11243-90)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adhesion G-protein coupled receptor F1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.903	0.209	0.000016	None	Gadd-DA_adgrf1_protein_levels__seqid___11243-90__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VEGFA protein levels (SeqId = 19437-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VEGFA protein levels (SeqId = 19437-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vascular endothelial growth factor A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000016	None	Gadd-DA_vegfa_protein_levels__seqid___19437-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TIAL1 protein levels (SeqId = 19131-184)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TIAL1 protein levels (SeqId = 19131-184)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nucleolysin TIAR	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000016	None	Gadd-DA_tial1_protein_levels__seqid___19131-184__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AMPD2 protein levels (SeqId = 18403-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AMPD2 protein levels (SeqId = 18403-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AMP deaminase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000016	None	Gadd-DA_ampd2_protein_levels__seqid___18403-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FOXO3 protein levels (SeqId = 11540-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FOXO3 protein levels (SeqId = 11540-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Forkhead box protein O3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000016	None	Gadd-DA_foxo3_protein_levels__seqid___11540-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	JMJD6 protein levels (SeqId = 18322-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	JMJD6 protein levels (SeqId = 18322-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000016	None	Gadd-DA_jmjd6_protein_levels__seqid___18322-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DTD1 protein levels (SeqId = 19194-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DTD1 protein levels (SeqId = 19194-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: D-aminoacyl-tRNA deacylase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000016	None	Gadd-DA_dtd1_protein_levels__seqid___19194-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANXA6 protein levels (SeqId = 5335-73)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANXA6 protein levels (SeqId = 5335-73)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Annexin A6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000016	None	Gadd-DA_anxa6_protein_levels__seqid___5335-73__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0356113	0.00825133	0.00001600527	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	0.0356007	0.00825134	0.00001609829	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0356006	0.00825134	0.00001609898	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0355988	0.00825134	0.00001611544	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0355924	0.00825134	0.0000161715	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	0.037898	0.00878697	0.00001621211	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0355561	0.00825135	0.00001649729	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0424084	0.00984157	0.00001649847	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0398515	0.00925309	0.00001666815	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07196133	chr3:188439649	3	188439649	LPP	Open sea	0.0355344	0.00825136	0.00001669398	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0355187	0.00825136	0.00001683786	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.0355054	0.00825137	0.00001696124	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MMP14 protein levels (SeqId = 5002-76)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MMP14 protein levels (SeqId = 5002-76)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Matrix metalloproteinase-14	774	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.77	0.179	0.000017	None	Gadd-DA_mmp14_protein_levels__seqid___5002-76__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AK1 protein levels (SeqId = 5012-67)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AK1 protein levels (SeqId = 5012-67)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adenylate kinase isoenzyme 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000017	None	Gadd-DA_ak1_protein_levels__seqid___5012-67__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GLRX2 protein levels (SeqId = 12486-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GLRX2 protein levels (SeqId = 12486-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutaredoxin-2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000017	None	Gadd-DA_glrx2_protein_levels__seqid___12486-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ITPRIPL1 protein levels (SeqId = 9221-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ITPRIPL1 protein levels (SeqId = 9221-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000017	None	Gadd-DA_itpripl1_protein_levels__seqid___9221-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKCQ protein levels (SeqId = 3817-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKCQ protein levels (SeqId = 3817-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein kinase C theta type	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000017	None	Gadd-DA_prkcq_protein_levels__seqid___3817-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NUDT3 protein levels (SeqId = 12796-44)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NUDT3 protein levels (SeqId = 12796-44)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Diphosphoinositol polyphosphate phosphohydrolase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000017	None	Gadd-DA_nudt3_protein_levels__seqid___12796-44__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFAIP8 protein levels (SeqId = 12563-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFAIP8 protein levels (SeqId = 12563-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor alpha-induced protein 8	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000017	None	Gadd-DA_tnfaip8_protein_levels__seqid___12563-2__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	-0.142932	0.0332306	0.00001707809	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0354893	0.00825137	0.00001711183	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg12120178	chr3:188103284	3	188103284	LPP	Open sea	0.128973	0.0299915	0.00001714376	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0354815	0.00825137	0.00001718443	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0373552	0.00868749	0.00001719886	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0354677	0.00825138	0.00001731454	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02579706	chr3:187960622	3	187960622	LPP	Open sea	0.0354646	0.00825138	0.00001734452	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0686729	0.0159841	0.00001736	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0579638	0.0134871	0.00001736906	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.041287	0.00960685	0.00001737248	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05984281	chr3:188413418	3	188413418	LPP	Open sea	0.0354544	0.00825138	0.00001744056	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.0388418	0.00904112	0.00001749248	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0354486	0.00825138	0.00001749605	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0354473	0.00825138	0.0000175085	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.042355	0.00985974	0.00001752227	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.035444	0.00825138	0.00001754064	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01683373	chr3:187916442	3	187916442	LPP	Open sea	0.194542	0.0452928	0.00001754889	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	0.0354429	0.00825138	0.00001755065	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0354389	0.00825139	0.00001758927	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0474604	0.0110517	0.00001762802	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	-0.0354322	0.00825139	0.0000176537	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0354314	0.00825139	0.00001766141	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0354247	0.00825139	0.00001772594	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0354218	0.00825139	0.00001775468	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.122809	0.0286139	0.00001780934	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O95445	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O95445	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0354002	0.0082514	0.00001796498	O95445	41361833_Josephine_Robertson_O95445_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0353983	0.0082514	0.00001798358	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	0.00033	0.000076	0.000018	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	COVID-19 Severity (Hospitalisation)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	COVID-19 Severity (Hospitalisation)	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	4232	1	Adults (18-65y)	Both	European	cg27524103	chr3:187957576	3	187957576	LPP	Open sea	0.052	0.0122	0.000018	None	Robert-F-Hillary_COVID-19_Severity_(Hospitalisation)_Fully-adjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB4A protein levels (SeqId = 16883-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB4A protein levels (SeqId = 16883-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-4A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000018	None	Gadd-DA_rab4a_protein_levels__seqid___16883-57__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EEF1D protein levels (SeqId = 17826-341)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EEF1D protein levels (SeqId = 17826-341)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Elongation factor 1-delta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000018	None	Gadd-DA_eef1d_protein_levels__seqid___17826-341__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BDNF protein levels (SeqId = 14047-78)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BDNF protein levels (SeqId = 14047-78)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Brain-derived neurotrophic factor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000018	None	Gadd-DA_bdnf_protein_levels__seqid___14047-78__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LYN protein levels (SeqId = 3381-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LYN protein levels (SeqId = 3381-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase Lyn	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000018	None	Gadd-DA_lyn_protein_levels__seqid___3381-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PF4 protein levels (SeqId = 2697-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PF4 protein levels (SeqId = 2697-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet factor 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000018	None	Gadd-DA_pf4_protein_levels__seqid___2697-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SUMO2 protein levels (SeqId = 19555-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SUMO2 protein levels (SeqId = 19555-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Small ubiquitin-related modifier 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000018	None	Gadd-DA_sumo2_protein_levels__seqid___19555-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NT5C2 protein levels (SeqId = 11288-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NT5C2 protein levels (SeqId = 11288-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytosolic purine 5'-nucleotidase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000018	None	Gadd-DA_nt5c2_protein_levels__seqid___11288-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TXNDC5 protein levels (SeqId = 11212-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXNDC5 protein levels (SeqId = 11212-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin domain-containing protein 5	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.899	0.209	0.000018	None	Gadd-DA_txndc5_protein_levels__seqid___11212-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0440856	0.0102774	0.00001801756	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.0361261	0.00842265	0.00001804935	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0353864	0.0082514	0.00001810098	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0422107	0.00984722	0.00001826211	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0353656	0.00825141	0.00001830747	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0353638	0.00825141	0.00001832531	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	0.0353581	0.00825141	0.00001838238	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0366251	0.00854864	0.00001844721	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.0353395	0.00825141	0.00001856995	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	-0.0353201	0.00825142	0.00001876654	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0353167	0.00825142	0.0000188011	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0353088	0.00825142	0.00001888317	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.181015	0.0423107	0.00001893501	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19528963	chr3:187941999	3	187941999	LPP	Open sea	0.156095	0.0364903	0.00001898276	None	39706196_Hannah-M.-Smith_bmi_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg16278897	chr3:188397356	3	188397356	LPP	Open sea	0.01167	0.00266	0.000019	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	LY9 protein levels (SeqId = 3324-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LY9 protein levels (SeqId = 3324-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: T-lymphocyte surface antigen Ly-9	774	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.82	0.193	0.000019	None	Gadd-DA_ly9_protein_levels__seqid___3324-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE3A protein levels (SeqId = 11226-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE3A protein levels (SeqId = 11226-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-protein ligase E3A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000019	None	Gadd-DA_ube3a_protein_levels__seqid___11226-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2E1 protein levels (SeqId = 14326-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2E1 protein levels (SeqId = 14326-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 E1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000019	None	Gadd-DA_ube2e1_protein_levels__seqid___14326-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FKBP3 protein levels (SeqId = 18383-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FKBP3 protein levels (SeqId = 18383-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase FKBP3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000019	None	Gadd-DA_fkbp3_protein_levels__seqid___18383-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RRM2B protein levels (SeqId = 8925-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RRM2B protein levels (SeqId = 8925-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribonucleoside-diphosphate reductase subunit M2 B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000019	None	Gadd-DA_rrm2b_protein_levels__seqid___8925-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBLCP1 protein levels (SeqId = 19124-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBLCP1 protein levels (SeqId = 19124-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-like domain-containing CTD phosphatase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000019	None	Gadd-DA_ublcp1_protein_levels__seqid___19124-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AREG protein levels (SeqId = 2970-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AREG protein levels (SeqId = 2970-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Amphiregulin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000019	None	Gadd-DA_areg_protein_levels__seqid___2970-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF4A3 protein levels (SeqId = 4997-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF4A3 protein levels (SeqId = 4997-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic initiation factor 4A-III	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000019	None	Gadd-DA_eif4a3_protein_levels__seqid___4997-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPBP protein levels (SeqId = 17165-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPBP protein levels (SeqId = 17165-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet basic protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000019	None	Gadd-DA_ppbp_protein_levels__seqid___17165-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRB10 protein levels (SeqId = 11358-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRB10 protein levels (SeqId = 11358-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Growth factor receptor-bound protein 10	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000019	None	Gadd-DA_grb10_protein_levels__seqid___11358-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2K protein levels (SeqId = 17380-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2K protein levels (SeqId = 17380-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 K	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.9	0.209	0.000019	None	Gadd-DA_ube2k_protein_levels__seqid___17380-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.035291	0.00825143	0.00001906654	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0352895	0.00825143	0.00001908186	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	-0.0424361	0.00992252	0.00001908514	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0387994	0.00907358	0.00001914166	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0452388	0.0105838	0.00001928979	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0352663	0.00825144	0.00001932445	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0382926	0.00896024	0.00001935452	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.0352622	0.00825144	0.0000193676	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0352563	0.00825144	0.00001942996	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0391274	0.00915996	0.00001953302	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0352383	0.00825144	0.00001962133	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0712571	0.0166884	0.00001968228	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0352264	0.00825145	0.00001974857	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0495105	0.0115999	0.00001983202	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0352147	0.00825145	0.00001987401	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0400059	0.00937701	0.00001999098	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0352035	0.00825145	0.00001999482	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0370058	0.00867392	0.00001999634	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Dugue PA	Melbourne Collaborative Cohort Study	31552803	2019-09-25	Smoking	EFO_0006527, EFO_0004318	Former vs never smoking	Supplementary table 1	DNA methylation	Smoking	Sex, country of birth, age, alcohol consumption, cell composition (reference based), batch effects	M Values	None	Illumina HumanMethylation450	Whole blood	None	156	1	Adults	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.09	0.0211	0.00002	None	31552803_Dugue-PA_smoking_former_vs_never_smoking
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	1.2	0.275	0.00002	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPD protein levels (SeqId = 18348-89)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPD protein levels (SeqId = 18348-89)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein D0	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.00002	None	Gadd-DA_hnrnpd_protein_levels__seqid___18348-89__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LANCL1 protein levels (SeqId = 13986-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LANCL1 protein levels (SeqId = 13986-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase LANCL1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.00002	None	Gadd-DA_lancl1_protein_levels__seqid___13986-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRDX6 protein levels (SeqId = 5018-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRDX6 protein levels (SeqId = 5018-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxiredoxin-6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.00002	None	Gadd-DA_prdx6_protein_levels__seqid___5018-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SCARF1 protein levels (SeqId = 5129-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SCARF1 protein levels (SeqId = 5129-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Scavenger receptor class F member 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.00002	None	Gadd-DA_scarf1_protein_levels__seqid___5129-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SEZ6L2 protein levels (SeqId = 3867-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SEZ6L2 protein levels (SeqId = 3867-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Seizure 6-like protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.00002	None	Gadd-DA_sez6l2_protein_levels__seqid___3867-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PURA protein levels (SeqId = 12537-88)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PURA protein levels (SeqId = 12537-88)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcriptional activator protein Pur-alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.00002	None	Gadd-DA_pura_protein_levels__seqid___12537-88__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	QPCT protein levels (SeqId = 7849-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	QPCT protein levels (SeqId = 7849-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutaminyl-peptide cyclotransferase	774	1	Adults (18-65 years)	Both	European	cg12314978	chr3:188324556	3	188324556	LPP	Open sea	0.37	0.087	0.00002	None	Gadd-DA_qpct_protein_levels__seqid___7849-3__somascan_protein_measurement
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	glyphosate	CHEBI_27744	discovery	10.5281/zenodo.5156585	DNA methylation	glyphosate	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	592	1	Adults	Males	European	cg25984398	chr3:188114354	3	188114354	LPP	Open sea	-0.00372	0.00087	0.00002	None	34516295_Hoang_glyphosate_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0595041	0.0139479	0.00002000999	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0507559	0.0118995	0.00002008174	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	0.142843	0.0334919	0.0000200963	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0469457	0.0110069	0.00002010377	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0351857	0.00825146	0.0000201891	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08825138	chr3:188157078	3	188157078	LPP	Open sea	0.0351816	0.00825146	0.00002023424	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03945529	chr3:188024721	3	188024721	LPP	Open sea	0.035174	0.00825146	0.00002031818	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0566562	0.0132918	0.00002034259	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0351624	0.00825147	0.0000204462	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0381925	0.00896299	0.00002046625	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0380554	0.00893505	0.00002065163	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0459834	0.0107976	0.00002069267	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0351401	0.00825147	0.00002069521	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0351293	0.00825148	0.00002081691	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.130002	0.0305414	0.0000208679	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0461958	0.0108543	0.00002094133	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12120178	chr3:188103284	3	188103284	LPP	Open sea	0.0351178	0.00825148	0.00002094697	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0351164	0.00825148	0.00002096278	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg01356198	chr3:187929513	3	187929513	LPP	Open sea	-0.169584	0.0399	0.000021	None	27105112_hiv_infection_cd4_tcells
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.046	0.01091	0.000021	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	KIRREL3 protein levels (SeqId = 4557-61)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIRREL3 protein levels (SeqId = 4557-61)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kin of IRRE-like protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000021	None	Gadd-DA_kirrel3_protein_levels__seqid___4557-61__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NCK1 protein levels (SeqId = 5014-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NCK1 protein levels (SeqId = 5014-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytoplasmic protein NCK1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000021	None	Gadd-DA_nck1_protein_levels__seqid___5014-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSME1 protein levels (SeqId = 5918-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSME1 protein levels (SeqId = 5918-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteasome activator complex subunit 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000021	None	Gadd-DA_psme1_protein_levels__seqid___5918-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APOBEC3G protein levels (SeqId = 13930-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APOBEC3G protein levels (SeqId = 13930-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA dC->dU-editing enzyme APOBEC-3G	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000021	None	Gadd-DA_apobec3g_protein_levels__seqid___13930-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DDX19B protein levels (SeqId = 5460-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DDX19B protein levels (SeqId = 5460-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ATP-dependent RNA helicase DDX19B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000021	None	Gadd-DA_ddx19b_protein_levels__seqid___5460-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TARS protein levels (SeqId = 18186-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TARS protein levels (SeqId = 18186-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Threonine--tRNA ligase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000021	None	Gadd-DA_tars_protein_levels__seqid___18186-15__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.03	0.00715	0.000021	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.035113	0.00825148	0.00002100111	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0544893	0.0128069	0.0000210639	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.035103	0.00825148	0.00002111564	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0399348	0.0093875	0.00002112517	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.149613	0.0351724	0.00002113222	None	39706196_Hannah-M.-Smith_glucose_discovery
Zhu X	-	26756918	2016-07-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	-	Table S1	DNA methylation	Smoking	Age, sex, alcohol consumption, body mass index and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	Regression coefficients are for inverse normally transformed DNA methylation	596	4	53.9	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.061	0.014347	0.0000212	-	26756918_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17125927	chr3:187924031	3	187924031	LPP	Open sea	-0.0350947	0.00825149	0.00002121026	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0350866	0.00825149	0.00002130328	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.0350851	0.00825149	0.00002132052	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0499678	0.0117522	0.00002134035	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0554541	0.0130439	0.00002137903	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0350728	0.00825149	0.00002146349	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0396885	0.00933758	0.00002147019	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	-0.035071	0.00825149	0.0000214841	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03548412	chr3:188063126	3	188063126	LPP	Open sea	-0.0355285	0.00835969	0.00002151115	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0413763	0.0097372	0.00002157654	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	-0.0370502	0.00872199	0.00002171035	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0561663	0.0132229	0.00002173678	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0350361	0.0082515	0.00002189312	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Neumann A	ALSPAC, GENR, INMA, NEST, PREDO	33184255	2020-11-12	ADHD	EFO_0003888	At birth	Supplementary data adhd_birth_results	ADHD	DNA methylation	maternal age, education level, smoking, gestational age, sex, cell composition (reference based)	ADHD score	Beta Values	Illumina HumanMethylation450	Cord Blood	None	2477	5	Infants	Both	European, African	cg18188653	chr3:188296976	3	188296976	LPP	Open sea	-3.367	1.514	0.000022	None	33184255_Neumann-A_adhd_at_birth
Gadd DA	Generation Scotland	35945220	31/07/2022	NEGR1 protein levels (SeqId = 7050-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NEGR1 protein levels (SeqId = 7050-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Neuronal growth regulator 1	774	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	0.755	0.178	0.000022	None	Gadd-DA_negr1_protein_levels__seqid___7050-5__somascan_protein_measurement
Zhao N	1989 CLUE II cohort	34008478	12-01-2020	lung cancer	None	None	Supplemental Table 1	lung cancer	DNA methylation	Age, Sex, Smoking, Body mass index, batch effects, pack-years based smoking methylation score, cell composition (reference based)	None	Other	Illumina HumanMethylationEPIC	whole blood	208 cases and 222 controls. Results are given as logOR corresponding to each 1% increase of methylation beta value	430	1	Adults	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.16	0.0376	0.000022	None	34008478_Zhao-N_lung_cancer
Gadd DA	Generation Scotland	35945220	31/07/2022	CASS4 protein levels (SeqId = 12855-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CASS4 protein levels (SeqId = 12855-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cas scaffolding protein family member 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000022	None	Gadd-DA_cass4_protein_levels__seqid___12855-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	USB1 protein levels (SeqId = 11328-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	USB1 protein levels (SeqId = 11328-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: U6 snRNA phosphodiesterase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.889	0.209	0.000022	None	Gadd-DA_usb1_protein_levels__seqid___11328-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKACA protein levels (SeqId = 3466-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKACA protein levels (SeqId = 3466-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: cAMP-dependent protein kinase catalytic subunit alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000022	None	Gadd-DA_prkaca_protein_levels__seqid___3466-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CRAT protein levels (SeqId = 12637-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRAT protein levels (SeqId = 12637-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carnitine O-acetyltransferase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.208	0.000022	None	Gadd-DA_crat_protein_levels__seqid___12637-7__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	0.035026	0.00825151	0.00002201382	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0350234	0.00825151	0.00002204441	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05160	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05160	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.0350145	0.00825151	0.0000221506	P05160	41361833_Josephine_Robertson_P05160_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	0.035012	0.00825151	0.00002218082	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0367387	0.00866104	0.0000223064	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.054662	0.0128901	0.00002242881	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg10666406	chr3:187872353	3	187872353	LPP	Island	0.140393	0.0331093	0.00002243393	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01766	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01766	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0349844	0.00825152	0.00002251386	P01766	41361833_Josephine_Robertson_P01766_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0349788	0.00825152	0.00002258168	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0349773	0.00825152	0.00002259956	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0349724	0.00825152	0.00002265935	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0349705	0.00825152	0.00002268302	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0456139	0.0107648	0.00002275729	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.0349641	0.00825152	0.00002276101	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.034953	0.00825153	0.0000228988	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0367954	0.00868701	0.00002292465	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	0.0383247	0.00904917	0.00002297871	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01356198	chr3:187929513	3	187929513	LPP	Open sea	0.0349454	0.00825153	0.00002299258	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	BCL10 protein levels (SeqId = 8768-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BCL10 protein levels (SeqId = 8768-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: B-cell lymphoma/leukemia 10	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000023	None	Gadd-DA_bcl10_protein_levels__seqid___8768-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGAP25 protein levels (SeqId = 11333-82)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGAP25 protein levels (SeqId = 11333-82)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 25	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000023	None	Gadd-DA_arhgap25_protein_levels__seqid___11333-82__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SEPHS1 protein levels (SeqId = 14083-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SEPHS1 protein levels (SeqId = 14083-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Selenide, water dikinase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000023	None	Gadd-DA_sephs1_protein_levels__seqid___14083-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJC19 protein levels (SeqId = 4545-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJC19 protein levels (SeqId = 4545-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitochondrial import inner membrane translocase subunit TIM14	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000023	None	Gadd-DA_dnajc19_protein_levels__seqid___4545-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CBR3 protein levels (SeqId = 14091-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBR3 protein levels (SeqId = 14091-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carbonyl reductase [NADPH] 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000023	None	Gadd-DA_cbr3_protein_levels__seqid___14091-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADH5 protein levels (SeqId = 11369-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADH5 protein levels (SeqId = 11369-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alcohol dehydrogenase class-3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000023	None	Gadd-DA_adh5_protein_levels__seqid___11369-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKAA2 protein levels (SeqId = 5245-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKAA2 protein levels (SeqId = 5245-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 5'-AMP-activated protein kinase subunit beta-2|5'-AMP-activated protein kinase catalytic subunit alpha-2|5'-AMP-activated protein kinase subunit gamma-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000023	None	Gadd-DA_prkaa2_protein_levels__seqid___5245-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PLCG2 protein levels (SeqId = 10070-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLCG2 protein levels (SeqId = 10070-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.89	0.209	0.000023	None	Gadd-DA_plcg2_protein_levels__seqid___10070-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	JAM3 protein levels (SeqId = 2998-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	JAM3 protein levels (SeqId = 2998-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Junctional adhesion molecule C	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000023	None	Gadd-DA_jam3_protein_levels__seqid___2998-53__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	-0.0376889	0.00889981	0.00002301476	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.156092	0.0368629	0.00002303518	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0349401	0.00825153	0.00002305844	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0349397	0.00825153	0.00002306305	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0349368	0.00825153	0.00002309926	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0349345	0.00825153	0.00002312758	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17392043	chr3:188495102	3	188495102	LPP	Open sea	0.034933	0.00825153	0.0000231464	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0349323	0.00825153	0.00002315482	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0468225	0.0110603	0.00002315912	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0467485	0.0110442	0.00002321436	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0349264	0.00825153	0.00002322864	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0349262	0.00825153	0.00002323179	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	-0.0349231	0.00825154	0.00002327101	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0496559	0.0117329	0.00002328327	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.054274	0.0128301	0.00002349061	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0511617	0.0120952	0.00002351819	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0348989	0.00825154	0.00002357636	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P23142	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P23142	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0412346	0.00974995	0.0000235929	P23142	41361833_Josephine_Robertson_P23142_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0753224	0.0178119	0.00002364106	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg26234183	chr3:187984142	3	187984142	LPP	Open sea	-0.165732	0.039208	0.000023798	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	0.0348813	0.00825155	0.0000238005	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0348773	0.00825155	0.00002385127	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NSF protein levels (SeqId = 13992-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NSF protein levels (SeqId = 13992-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vesicle-fusing ATPase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000024	None	Gadd-DA_nsf_protein_levels__seqid___13992-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPA1 protein levels (SeqId = 5021-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPA1 protein levels (SeqId = 5021-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inorganic pyrophosphatase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000024	None	Gadd-DA_ppa1_protein_levels__seqid___5021-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL23R protein levels (SeqId = 5088-175)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL23R protein levels (SeqId = 5088-175)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-23 receptor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000024	None	Gadd-DA_il23r_protein_levels__seqid___5088-175__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0376379	0.00890772	0.00002400493	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0348368	0.00825156	0.00002437679	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0500189	0.01185	0.00002446608	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0348271	0.00825156	0.00002450417	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	-0.0365321	0.00866024	0.00002475528	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.034806	0.00825157	0.00002478344	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0510085	0.0120937	0.00002481942	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	-0.036452	0.00864563	0.00002499051	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02711245	chr3:188013909	3	188013909	LPP	Open sea	0.00099	0.00024	0.000025	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05548945	chr3:188550738	3	188550738	LPP	Open sea	-0.0025	0.00059	0.000025	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Neumann A	ALSPAC, GENR, INMA, NEST, PREDO	33184255	2020-11-12	ADHD	EFO_0003888	At birth	Supplementary data adhd_birth_results	ADHD	DNA methylation	maternal age, education level, smoking, gestational age, sex, cell composition (reference based)	ADHD score	Beta Values	Illumina HumanMethylation450	Cord Blood	None	2477	5	Infants	Both	European, African	cg12298996	chr3:188272255	3	188272255	LPP	Open sea	-2.18	0.504	0.000025	None	33184255_Neumann-A_adhd_at_birth
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	1.7	0.4	0.000025	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-1.3	0.307	0.000025	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.18	0.0438	0.000025	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	HAMP protein levels (SeqId = 3504-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HAMP protein levels (SeqId = 3504-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepcidin	774	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.72	0.172	0.000025	None	Gadd-DA_hamp_protein_levels__seqid___3504-58__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAD23B protein levels (SeqId = 12522-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAD23B protein levels (SeqId = 12522-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UV excision repair protein RAD23 homolog B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000025	None	Gadd-DA_rad23b_protein_levels__seqid___12522-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMEM87B protein levels (SeqId = 13485-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMEM87B protein levels (SeqId = 13485-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transmembrane protein 87B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000025	None	Gadd-DA_tmem87b_protein_levels__seqid___13485-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACADM protein levels (SeqId = 17333-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACADM protein levels (SeqId = 17333-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000025	None	Gadd-DA_acadm_protein_levels__seqid___17333-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BCL2A1 protein levels (SeqId = 3413-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BCL2A1 protein levels (SeqId = 3413-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bcl-2-related protein A1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000025	None	Gadd-DA_bcl2a1_protein_levels__seqid___3413-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB22A protein levels (SeqId = 12408-333)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB22A protein levels (SeqId = 12408-333)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-22A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.882	0.209	0.000025	None	Gadd-DA_rab22a_protein_levels__seqid___12408-333__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0560207	0.0132875	0.00002501207	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0347849	0.00825157	0.00002506613	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0347842	0.00825157	0.00002507554	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.0347733	0.00825158	0.00002522327	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0552903	0.0131216	0.00002527261	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0395701	0.00939171	0.00002531692	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0410903	0.00975388	0.00002538255	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0410947	0.00975505	0.00002538915	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0347591	0.00825158	0.00002541646	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0377376	0.00896608	0.00002581121	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	-0.0347301	0.00825159	0.00002581412	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03548412	chr3:188063126	3	188063126	LPP	Open sea	-0.0351208	0.00834569	0.00002588783	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	CDNF protein levels (SeqId = 4962-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CDNF protein levels (SeqId = 4962-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cerebral dopamine neurotrophic factor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000026	None	Gadd-DA_cdnf_protein_levels__seqid___4962-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGEF10 protein levels (SeqId = 9061-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGEF10 protein levels (SeqId = 9061-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho guanine nucleotide exchange factor 10	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000026	None	Gadd-DA_arhgef10_protein_levels__seqid___9061-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SCGB1D2 protein levels (SeqId = 6508-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SCGB1D2 protein levels (SeqId = 6508-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Secretoglobin family 1D member 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000026	None	Gadd-DA_scgb1d2_protein_levels__seqid___6508-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPARC protein levels (SeqId = 3043-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPARC protein levels (SeqId = 3043-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SPARC	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000026	None	Gadd-DA_sparc_protein_levels__seqid___3043-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAT3 protein levels (SeqId = 10346-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAT3 protein levels (SeqId = 10346-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal transducer and activator of transcription 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000026	None	Gadd-DA_stat3_protein_levels__seqid___10346-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MOB1A protein levels (SeqId = 12426-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MOB1A protein levels (SeqId = 12426-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MOB kinase activator 1A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.879	0.209	0.000026	None	Gadd-DA_mob1a_protein_levels__seqid___12426-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPIF protein levels (SeqId = 5248-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPIF protein levels (SeqId = 5248-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase F, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000026	None	Gadd-DA_ppif_protein_levels__seqid___5248-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ASF1A protein levels (SeqId = 18172-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASF1A protein levels (SeqId = 18172-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histone chaperone ASF1A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000026	None	Gadd-DA_asf1a_protein_levels__seqid___18172-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FCRL1 protein levels (SeqId = 5728-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FCRL1 protein levels (SeqId = 5728-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fc receptor-like protein 1	774	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.82	0.195	0.000026	None	Gadd-DA_fcrl1_protein_levels__seqid___5728-60__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.0347155	0.00825159	0.00002601824	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.0347113	0.0082516	0.00002607681	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	0.0368603	0.00876429	0.00002617796	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0346931	0.0082516	0.0000263325	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0754307	0.0179435	0.00002640334	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.0349461	0.00831463	0.00002649983	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0346697	0.00825161	0.00002666385	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	-0.0339779	0.00808779	0.0000267154	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0399881	0.00951975	0.00002678568	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.0346538	0.00825161	0.00002689136	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.0346532	0.00825161	0.00002689988	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0346502	0.00825161	0.00002694322	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0043	0.001	0.000027	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	FAIM3 protein levels (SeqId = 6574-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAIM3 protein levels (SeqId = 6574-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fas apoptotic inhibitory molecule 3	774	1	Adults (18-65 years)	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	0.659	0.157	0.000027	None	Gadd-DA_faim3_protein_levels__seqid___6574-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VEGFC protein levels (SeqId = 3132-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VEGFC protein levels (SeqId = 3132-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vascular endothelial growth factor C	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.879	0.209	0.000027	None	Gadd-DA_vegfc_protein_levels__seqid___3132-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UBASH3B protein levels (SeqId = 12558-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBASH3B protein levels (SeqId = 12558-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-associated and SH3 domain-containing protein B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000027	None	Gadd-DA_ubash3b_protein_levels__seqid___12558-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	USP15 protein levels (SeqId = 19161-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	USP15 protein levels (SeqId = 19161-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin carboxyl-terminal hydrolase 15	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000027	None	Gadd-DA_usp15_protein_levels__seqid___19161-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SH3BP2 protein levels (SeqId = 7769-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SH3BP2 protein levels (SeqId = 7769-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SH3 domain-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000027	None	Gadd-DA_sh3bp2_protein_levels__seqid___7769-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NMI protein levels (SeqId = 17512-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NMI protein levels (SeqId = 17512-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-myc-interactor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000027	None	Gadd-DA_nmi_protein_levels__seqid___17512-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SMAD4 protein levels (SeqId = 12022-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMAD4 protein levels (SeqId = 12022-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mothers against decapentaplegic homolog 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000027	None	Gadd-DA_smad4_protein_levels__seqid___12022-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CHMP2B protein levels (SeqId = 17350-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHMP2B protein levels (SeqId = 17350-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Charged multivesicular body protein 2b	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000027	None	Gadd-DA_chmp2b_protein_levels__seqid___17350-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ASH2L protein levels (SeqId = 12832-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASH2L protein levels (SeqId = 12832-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Set1/Ash2 histone methyltransferase complex subunit ASH2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000027	None	Gadd-DA_ash2l_protein_levels__seqid___12832-10__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.025	0.00601	0.000027	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	0.0346454	0.00825161	0.00002701328	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.034645	0.00825161	0.00002701877	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0346437	0.00825162	0.0000270371	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0460023	0.0109579	0.00002707665	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0346401	0.00825162	0.00002708967	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0346336	0.00825162	0.00002718356	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0387802	0.00924095	0.00002725978	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0392346	0.00935019	0.00002731092	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0586057	0.0139699	0.00002743156	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0431818	0.0102976	0.00002764371	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.181591	0.0433088	0.00002767324	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03548412	chr3:188063126	3	188063126	LPP	Open sea	-0.035061	0.00836262	0.00002774085	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	0.0373833	0.00891822	0.00002783787	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.037	0.00878	0.000028	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	NMB protein levels (SeqId = 9321-400)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NMB protein levels (SeqId = 9321-400)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Neuromedin-B	774	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.926	0.221	0.000028	None	Gadd-DA_nmb_protein_levels__seqid___9321-400__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KLK15 protein levels (SeqId = 6491-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLK15 protein levels (SeqId = 6491-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kallikrein-15	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000028	None	Gadd-DA_klk15_protein_levels__seqid___6491-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PCTK1 protein levels (SeqId = 16867-76)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PCTK1 protein levels (SeqId = 16867-76)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cyclin-dependent kinase 16	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000028	None	Gadd-DA_pctk1_protein_levels__seqid___16867-76__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPIA protein levels (SeqId = 3844-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPIA protein levels (SeqId = 3844-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000028	None	Gadd-DA_ppia_protein_levels__seqid___3844-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ING1 protein levels (SeqId = 3888-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ING1 protein levels (SeqId = 3888-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inhibitor of growth protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000028	None	Gadd-DA_ing1_protein_levels__seqid___3888-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FKBP2 protein levels (SeqId = 9339-204)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FKBP2 protein levels (SeqId = 9339-204)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase FKBP2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000028	None	Gadd-DA_fkbp2_protein_levels__seqid___9339-204__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NAA10 protein levels (SeqId = 17854-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAA10 protein levels (SeqId = 17854-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-alpha-acetyltransferase 10	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.875	0.209	0.000028	None	Gadd-DA_naa10_protein_levels__seqid___17854-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GHRH protein levels (SeqId = 16293-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GHRH protein levels (SeqId = 16293-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Somatoliberin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000028	None	Gadd-DA_ghrh_protein_levels__seqid___16293-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PCBD2 protein levels (SeqId = 6899-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PCBD2 protein levels (SeqId = 6899-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pterin-4-alpha-carbinolamine dehydratase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000028	None	Gadd-DA_pcbd2_protein_levels__seqid___6899-37__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0447928	0.0106897	0.00002802393	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0350554	0.00836731	0.0000281129	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.0392045	0.0093588	0.00002817586	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0584665	0.0139621	0.0000283665	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-0.0345282	0.00825165	0.00002875866	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	-0.0345244	0.00825165	0.00002881696	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0345182	0.00825165	0.00002891245	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Battram T	GEO	30045751	2020-09-15	Alzheimer's disease	EFO_0000249	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE66351	None	DNA methylation	Alzheimer's disease	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Brain	Some brain tissue was cell sorted, but all data analysed together for this re-analysis of GEO data.	190	1	Geriatrics	Both	Unclear	cg00119073	chr3:187870713	3	187870713	LPP	North shore	-0.0234	0.00544	0.000029	None	30045751_Battram-T_alzheimer_s_disease_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse66351
Gadd DA	Generation Scotland	35945220	31/07/2022	LY9 protein levels (SeqId = 3324-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LY9 protein levels (SeqId = 3324-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: T-lymphocyte surface antigen Ly-9	774	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.63	0.151	0.000029	None	Gadd-DA_ly9_protein_levels__seqid___3324-51__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg17023114	chr3:188590442	3	188590442	LPP	Open sea	-0.00968	0.00226	0.000029	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21176488	chr3:188251742	3	188251742	LPP	Open sea	0.0084	0.002	0.000029	None	33450751_Mulder-RH_sex_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	NRP1 protein levels (SeqId = 5542-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NRP1 protein levels (SeqId = 5542-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Neuropilin-1	774	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.7	0.167	0.000029	None	Gadd-DA_nrp1_protein_levels__seqid___5542-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	YWHAZ protein levels (SeqId = 5858-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	YWHAZ protein levels (SeqId = 5858-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 14-3-3 protein zeta/delta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000029	None	Gadd-DA_ywhaz_protein_levels__seqid___5858-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DBI protein levels (SeqId = 16919-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DBI protein levels (SeqId = 16919-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-CoA-binding protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000029	None	Gadd-DA_dbi_protein_levels__seqid___16919-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RMDN1 protein levels (SeqId = 7096-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RMDN1 protein levels (SeqId = 7096-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Regulator of microtubule dynamics protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000029	None	Gadd-DA_rmdn1_protein_levels__seqid___7096-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EZR protein levels (SeqId = 9753-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EZR protein levels (SeqId = 9753-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ezrin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000029	None	Gadd-DA_ezr_protein_levels__seqid___9753-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SYT4 protein levels (SeqId = 17355-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SYT4 protein levels (SeqId = 17355-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Synaptotagmin-4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.873	0.209	0.000029	None	Gadd-DA_syt4_protein_levels__seqid___17355-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AIFM1 protein levels (SeqId = 9522-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AIFM1 protein levels (SeqId = 9522-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Apoptosis-inducing factor 1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000029	None	Gadd-DA_aifm1_protein_levels__seqid___9522-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLEC4G protein levels (SeqId = 10781-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLEC4G protein levels (SeqId = 10781-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-type lectin domain family 4 member G	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000029	None	Gadd-DA_clec4g_protein_levels__seqid___10781-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARPC3 protein levels (SeqId = 13573-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARPC3 protein levels (SeqId = 13573-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Actin-related protein 2/3 complex subunit 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.88	0.209	0.000029	None	Gadd-DA_arpc3_protein_levels__seqid___13573-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	0.0345077	0.00825165	0.00002907479	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	-0.131751	0.0315074	0.00002909251	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0373888	0.00894249	0.00002918748	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.0344955	0.00825166	0.00002926358	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0415438	0.00993872	0.00002932094	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.183957	0.0440216	0.00002944242	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.218301	0.052249	0.00002954158	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0344744	0.00825166	0.0000295946	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	0.0403554	0.0096594	0.00002959992	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	0.0414911	0.00993436	0.00002977058	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0344498	0.00825167	0.00002998568	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg05984281	chr3:188413418	3	188413418	LPP	Open sea	-0.017	0.00404	0.00003	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	RSRP1 protein levels (SeqId = 9050-170)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RSRP1 protein levels (SeqId = 9050-170)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Arginine/serine-rich protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.00003	None	Gadd-DA_rsrp1_protein_levels__seqid___9050-170__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAHD1 protein levels (SeqId = 17819-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAHD1 protein levels (SeqId = 17819-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acylpyruvase FAHD1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.00003	None	Gadd-DA_fahd1_protein_levels__seqid___17819-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMA6 protein levels (SeqId = 3860-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMA6 protein levels (SeqId = 3860-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteasome subunit alpha type-6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.00003	None	Gadd-DA_psma6_protein_levels__seqid___3860-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPME1 protein levels (SeqId = 17852-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPME1 protein levels (SeqId = 17852-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein phosphatase methylesterase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.00003	None	Gadd-DA_ppme1_protein_levels__seqid___17852-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAP2K3 protein levels (SeqId = 6151-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAP2K3 protein levels (SeqId = 6151-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dual specificity mitogen-activated protein kinase kinase 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.00003	None	Gadd-DA_map2k3_protein_levels__seqid___6151-18__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	-0.0344442	0.00825167	0.00003007532	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.392899	0.0942	0.0000301	None	27105112_hiv_infection_cd4_tcells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	0.0361958	0.00867256	0.00003015475	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.0512574	0.0122818	0.00003017402	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0536656	0.0128597	0.00003021129	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0449792	0.0107786	0.00003023423	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.174518	0.0418311	0.00003034615	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0376905	0.0090352	0.00003043118	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0344179	0.00825168	0.00003049832	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0412633	0.00989402	0.00003056335	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0572302	0.013724	0.00003062291	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0559704	0.0134225	0.00003064916	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.113572	0.0272456	0.00003081527	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0582241	0.0139674	0.00003082635	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.034397	0.00825169	0.00003083962	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0343931	0.00825169	0.00003090419	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	-0.051408	0.0123354	0.00003096967	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	FLRT1 protein levels (SeqId = 4547-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FLRT1 protein levels (SeqId = 4547-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leucine-rich repeat transmembrane protein FLRT1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000031	None	Gadd-DA_flrt1_protein_levels__seqid___4547-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLEC2B protein levels (SeqId = 7786-83)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLEC2B protein levels (SeqId = 7786-83)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-type lectin domain family 2 member B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000031	None	Gadd-DA_clec2b_protein_levels__seqid___7786-83__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05299185	chr3:187872455	3	187872455	LPP	South shore	0.0343851	0.00825169	0.00003103469	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0343797	0.00825169	0.00003112386	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg19528963	chr3:187941999	3	187941999	LPP	Open sea	-0.148305	0.0356067	0.00003126728	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12314978	chr3:188324556	3	188324556	LPP	Open sea	0.0343707	0.00825169	0.00003127303	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg07196133	chr3:188439649	3	188439649	LPP	Open sea	-0.274274	0.0659	0.0000313	None	27105112_hiv_infection_cd4_tcells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0482352	0.0115811	0.00003131296	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0360999	0.00866899	0.00003141512	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0553359	0.0132942	0.00003167279	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0343453	0.0082517	0.00003169833	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15131848	chr3:187875197	3	187875197	LPP	South shelf	0.173228	0.0416275	0.00003178407	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0343359	0.0082517	0.00003185748	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0356183	0.00856196	0.00003199737	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	HDAC2 protein levels (SeqId = 18897-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HDAC2 protein levels (SeqId = 18897-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histone deacetylase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000032	None	Gadd-DA_hdac2_protein_levels__seqid___18897-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PGK2 protein levels (SeqId = 13936-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGK2 protein levels (SeqId = 13936-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphoglycerate kinase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000032	None	Gadd-DA_pgk2_protein_levels__seqid___13936-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NFU1 protein levels (SeqId = 7770-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NFU1 protein levels (SeqId = 7770-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NFU1 iron-sulfur cluster scaffold homolog, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.869	0.209	0.000032	None	Gadd-DA_nfu1_protein_levels__seqid___7770-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RNF41 protein levels (SeqId = 13411-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RNF41 protein levels (SeqId = 13411-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase NRDP1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.871	0.209	0.000032	None	Gadd-DA_rnf41_protein_levels__seqid___13411-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COMMD7 protein levels (SeqId = 2823-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COMMD7 protein levels (SeqId = 2823-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: COMM domain-containing protein 7	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000032	None	Gadd-DA_commd7_protein_levels__seqid___2823-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GMFG protein levels (SeqId = 13062-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GMFG protein levels (SeqId = 13062-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glia maturation factor gamma	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000032	None	Gadd-DA_gmfg_protein_levels__seqid___13062-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.04057	0.00975629	0.00003223904	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0343118	0.00825171	0.00003226594	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01009	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01009	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.034308	0.00825171	0.00003233141	P01009	41361833_Josephine_Robertson_P01009_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.0978901	0.0235492	0.0000324244	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0343013	0.00825171	0.00003244771	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0533821	0.0128423	0.00003246705	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0342962	0.00825171	0.0000325351	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22209756	chr3:187901412	3	187901412	LPP	Open sea	0.0342962	0.00825171	0.00003253524	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0374824	0.0090227	0.00003282347	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	0.0342716	0.00825172	0.00003296236	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	1.01908	0.2455	0.000033	-	27105112_hiv_infection_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.036	0.00862	0.000033	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ARID3A protein levels (SeqId = 3875-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARID3A protein levels (SeqId = 3875-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AT-rich interactive domain-containing protein 3A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.208	0.000033	None	Gadd-DA_arid3a_protein_levels__seqid___3875-62__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GNAI1 protein levels (SeqId = 19271-64)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GNAI1 protein levels (SeqId = 19271-64)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Guanine nucleotide-binding protein G(i) subunit alpha-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.869	0.209	0.000033	None	Gadd-DA_gnai1_protein_levels__seqid___19271-64__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	USP8 protein levels (SeqId = 13450-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	USP8 protein levels (SeqId = 13450-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin carboxyl-terminal hydrolase 8	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000033	None	Gadd-DA_usp8_protein_levels__seqid___13450-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB13 protein levels (SeqId = 19282-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB13 protein levels (SeqId = 19282-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-13	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000033	None	Gadd-DA_rab13_protein_levels__seqid___19282-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KLHL12 protein levels (SeqId = 12695-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLHL12 protein levels (SeqId = 12695-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kelch-like protein 12	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000033	None	Gadd-DA_klhl12_protein_levels__seqid___12695-62__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IFNLR1 protein levels (SeqId = 7192-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFNLR1 protein levels (SeqId = 7192-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon lambda receptor 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000033	None	Gadd-DA_ifnlr1_protein_levels__seqid___7192-37__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCDC50 protein levels (SeqId = 12399-194)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCDC50 protein levels (SeqId = 12399-194)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coiled-coil domain-containing protein 50	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.868	0.209	0.000033	None	Gadd-DA_ccdc50_protein_levels__seqid___12399-194__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VAV1 protein levels (SeqId = 5275-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VAV1 protein levels (SeqId = 5275-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proto-oncogene vav	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.208	0.000033	None	Gadd-DA_vav1_protein_levels__seqid___5275-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0732712	0.0176458	0.00003309587	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	0.035615	0.00857892	0.0000332235	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.203994	0.0491456	0.00003328985	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0517054	0.0124572	0.0000333412	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0342452	0.00825173	0.00003342523	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0532215	0.0128248	0.00003345225	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.045323	0.010922	0.00003347882	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.045597	0.0109881	0.00003348328	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	0.0368624	0.00888682	0.00003373124	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0590868	0.0142479	0.00003386755	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2L3 protein levels (SeqId = 3874-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2L3 protein levels (SeqId = 3874-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 L3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000034	None	Gadd-DA_ube2l3_protein_levels__seqid___3874-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TP53I3 protein levels (SeqId = 17748-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TP53I3 protein levels (SeqId = 17748-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Quinone oxidoreductase PIG3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000034	None	Gadd-DA_tp53i3_protein_levels__seqid___17748-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TXNRD1 protein levels (SeqId = 13967-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXNRD1 protein levels (SeqId = 13967-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin reductase 1, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000034	None	Gadd-DA_txnrd1_protein_levels__seqid___13967-14__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0342129	0.00825174	0.00003400178	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0371176	0.0089541	0.00003412396	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0457915	0.011048	0.00003420406	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0341923	0.00825174	0.00003437416	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0341827	0.00825175	0.00003454869	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.147139	0.0355238	0.00003458492	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.0341799	0.00825175	0.00003459998	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	-0.0341776	0.00825175	0.00003464253	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	-0.03738	0.00902867	0.00003490315	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_3
Neumann A	ALSPAC, GENR, INMA, NEST, PREDO	33184255	2020-11-12	ADHD	EFO_0003888	At birth	Supplementary data adhd_birth_results	ADHD	DNA methylation	maternal age, education level, smoking, gestational age, sex, cell composition (reference based)	ADHD score	Beta Values	Illumina HumanMethylation450	Cord Blood	None	2477	5	Infants	Both	European, African	cg18603679	chr3:188247767	3	188247767	LPP	Open sea	-1.645	0.388	0.000035	None	33184255_Neumann-A_adhd_at_birth
Gadd DA	Generation Scotland	35945220	31/07/2022	C7orf69 protein levels (SeqId = 9544-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C7orf69 protein levels (SeqId = 9544-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uncharacterized protein C7orf69	774	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	0.735	0.178	0.000035	None	Gadd-DA_c7orf69_protein_levels__seqid___9544-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPAG11B protein levels (SeqId = 5762-35)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPAG11B protein levels (SeqId = 5762-35)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sperm-associated antigen 11B	774	1	Adults (18-65 years)	Both	European	cg27524103	chr3:187957576	3	187957576	LPP	Open sea	0.54	0.131	0.000035	None	Gadd-DA_spag11b_protein_levels__seqid___5762-35__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MTIF3 protein levels (SeqId = 7852-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MTIF3 protein levels (SeqId = 7852-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Translation initiation factor IF-3, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000035	None	Gadd-DA_mtif3_protein_levels__seqid___7852-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPIH protein levels (SeqId = 12449-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPIH protein levels (SeqId = 12449-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase H	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000035	None	Gadd-DA_ppih_protein_levels__seqid___12449-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CD47 protein levels (SeqId = 6653-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD47 protein levels (SeqId = 6653-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leukocyte surface antigen CD47	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.87	0.209	0.000035	None	Gadd-DA_cd47_protein_levels__seqid___6653-58__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0690082	0.0166708	0.00003500496	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0486249	0.0117501	0.00003518891	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.0878418	0.0212278	0.00003519285	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0341427	0.00825176	0.00003528776	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	0.0341417	0.00825176	0.00003530621	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0343627	0.00830542	0.00003532432	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.0341319	0.00825176	0.00003548836	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0341271	0.00825176	0.00003557936	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0445489	0.0107721	0.00003560391	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0341198	0.00825176	0.00003571652	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg02904838	chr3:187871519	3	187871519	LPP	Island	0.858648	0.2078	0.0000358	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.0341102	0.00825177	0.00003589806	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0454977	0.011007	0.00003592537	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17483	1	Adults (18-65y)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.026	0.00627	0.000036	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Basic_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.065	0.0158	0.000036	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	UPP1 protein levels (SeqId = 19448-104)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UPP1 protein levels (SeqId = 19448-104)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uridine phosphorylase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000036	None	Gadd-DA_upp1_protein_levels__seqid___19448-104__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0543296	0.0131514	0.00003630738	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	0.0340825	0.00825177	0.00003642677	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01622023	chr3:187941818	3	187941818	LPP	Open sea	0.222392	0.0538486	0.00003645498	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.0577813	0.0139911	0.00003649862	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	0.0354168	0.00857612	0.00003652582	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0343782	0.00832488	0.00003654551	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0340759	0.00825178	0.00003655231	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0340632	0.00825178	0.00003679935	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0340602	0.00825178	0.000036857	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	RHOG protein levels (SeqId = 12540-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RHOG protein levels (SeqId = 12540-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho-related GTP-binding protein RhoG	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000037	None	Gadd-DA_rhog_protein_levels__seqid___12540-25__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF8 protein levels (SeqId = 19570-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF8 protein levels (SeqId = 19570-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 8	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000037	None	Gadd-DA_fgf8_protein_levels__seqid___19570-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	S100A4 protein levels (SeqId = 14116-129)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	S100A4 protein levels (SeqId = 14116-129)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein S100-A4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000037	None	Gadd-DA_s100a4_protein_levels__seqid___14116-129__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0442018	0.0107159	0.00003729717	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0402984	0.00977045	0.00003735694	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0340255	0.00825179	0.0000375371	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	0.0340244	0.00825179	0.00003755769	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0357894	0.00868138	0.00003767736	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	-0.0340147	0.00825179	0.00003775109	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0575079	0.0139528	0.0000378307	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	-0.0340042	0.0082518	0.00003795888	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	EPO protein levels (SeqId = 5813-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPO protein levels (SeqId = 5813-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Erythropoietin	774	1	Adults (18-65 years)	Both	European	cg14932952	chr3:187943282	3	187943282	LPP	Open sea	0.67	0.163	0.000038	None	Gadd-DA_epo_protein_levels__seqid___5813-58__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IFNA21 protein levels (SeqId = 15404-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IFNA21 protein levels (SeqId = 15404-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interferon alpha-21	774	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	0.73	0.177	0.000038	None	Gadd-DA_ifna21_protein_levels__seqid___15404-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RANBP1 protein levels (SeqId = 18191-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RANBP1 protein levels (SeqId = 18191-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ran-specific GTPase-activating protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000038	None	Gadd-DA_ranbp1_protein_levels__seqid___18191-23__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DCI protein levels (SeqId = 19367-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DCI protein levels (SeqId = 19367-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Enoyl-CoA delta isomerase 1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000038	None	Gadd-DA_dci_protein_levels__seqid___19367-34__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0339996	0.0082518	0.0000380507	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0433604	0.0105256	0.00003817767	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0679799	0.0165061	0.00003834696	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.154072	0.0374137	0.00003838392	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0339784	0.0082518	0.0000384779	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	-0.0339765	0.0082518	0.00003851586	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0480441	0.0116686	0.00003852742	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03945529	chr3:188024721	3	188024721	LPP	Open sea	0.0361452	0.00877999	0.00003863241	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0339613	0.00825181	0.00003882463	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0401441	0.00975515	0.00003890154	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	FTH1 protein levels (SeqId = 5934-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FTH1 protein levels (SeqId = 5934-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ferritin heavy chain|Ferritin light chain	774	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-1.29	0.313	0.000039	None	Gadd-DA_fth1_protein_levels__seqid___5934-1__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23493553	chr3:188055123	3	188055123	LPP	Open sea	0.002	None	0.000039	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPAB protein levels (SeqId = 8894-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPAB protein levels (SeqId = 8894-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein A/B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000039	None	Gadd-DA_hnrnpab_protein_levels__seqid___8894-80__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KARS protein levels (SeqId = 19249-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KARS protein levels (SeqId = 19249-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lysine--tRNA ligase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000039	None	Gadd-DA_kars_protein_levels__seqid___19249-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TWF1 protein levels (SeqId = 12871-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TWF1 protein levels (SeqId = 12871-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Twinfilin-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000039	None	Gadd-DA_twf1_protein_levels__seqid___12871-10__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.033948	0.00825181	0.00003909803	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0386126	0.00938621	0.0000391394	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	0.0371666	0.00903511	0.00003916982	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0339442	0.00825181	0.00003917612	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0569917	0.0138559	0.00003923974	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0372654	0.00906047	0.00003927271	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0437523	0.0106377	0.00003927539	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08825138	chr3:188157078	3	188157078	LPP	Open sea	-0.0339361	0.00825182	0.00003934207	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH29	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH29	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	-0.0733772	0.0178424	0.00003935011	A0A0C4DH29	41361833_Josephine_Robertson_A0A0C4DH29_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.033927	0.00825182	0.00003953121	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23493553	chr3:188055123	3	188055123	LPP	Open sea	-0.0333367	0.00810873	0.00003957222	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0491305	0.0119532	0.00003973856	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0442282	0.0107618	0.00003982532	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0355934	0.00866109	0.00003985452	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15131848	chr3:187875197	3	187875197	LPP	South shelf	0.0027	None	0.00004	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	MMP14 protein levels (SeqId = 5002-76)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MMP14 protein levels (SeqId = 5002-76)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Matrix metalloproteinase-14	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.00004	None	Gadd-DA_mmp14_protein_levels__seqid___5002-76__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGAP30 protein levels (SeqId = 12807-89)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGAP30 protein levels (SeqId = 12807-89)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 30	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.00004	None	Gadd-DA_arhgap30_protein_levels__seqid___12807-89__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0369866	0.00900216	0.00004001591	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0339021	0.00825183	0.00004005006	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0395828	0.00963594	0.00004015692	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	0.033896	0.00825183	0.00004018024	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0338905	0.00825183	0.00004029591	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0338791	0.00825183	0.00004053747	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	-0.0338683	0.00825183	0.00004076686	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	-0.130151	0.0317123	0.00004077023	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	-0.170816	0.0416278	0.00004088807	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.0338595	0.00825184	0.00004095495	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0099	0.0024	0.000041	None	33450751_Mulder-RH_sex_discovery
Tan Q	Middle<U+2010>aged Danish Twins (MADT)	34427971	Aug 24, 2021	Age	EFO_0000246	Discovery	Table S1	DNA methylation	Age	Cell composition (reference based)	M values	years	Illumina HumanMethylation450	Whole blood	None	492	1	Geriatrics	Males	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0104	0.00246	0.000041	None	34427971_Tan-Q_age_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	NAALAD2 protein levels (SeqId = 7986-98)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAALAD2 protein levels (SeqId = 7986-98)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-acetylated-alpha-linked acidic dipeptidase 2	774	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.63	0.155	0.000041	None	Gadd-DA_naalad2_protein_levels__seqid___7986-98__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LEMD1 protein levels (SeqId = 8040-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LEMD1 protein levels (SeqId = 8040-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: LEM domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.858	0.209	0.000041	None	Gadd-DA_lemd1_protein_levels__seqid___8040-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARL3 protein levels (SeqId = 12571-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARL3 protein levels (SeqId = 12571-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor-like protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000041	None	Gadd-DA_arl3_protein_levels__seqid___12571-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ALDH6A1 protein levels (SeqId = 19136-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ALDH6A1 protein levels (SeqId = 19136-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000041	None	Gadd-DA_aldh6a1_protein_levels__seqid___19136-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLEC1B protein levels (SeqId = 4332-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLEC1B protein levels (SeqId = 4332-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-type lectin domain family 1 member B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000041	None	Gadd-DA_clec1b_protein_levels__seqid___4332-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDRG1 protein levels (SeqId = 12593-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDRG1 protein levels (SeqId = 12593-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: p53 and DNA damage-regulated protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000041	None	Gadd-DA_pdrg1_protein_levels__seqid___12593-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMOD1 protein levels (SeqId = 12595-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMOD1 protein levels (SeqId = 12595-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tropomodulin-1	774	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	1.14	0.279	0.000041	None	Gadd-DA_tmod1_protein_levels__seqid___12595-11__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0444483	0.0108332	0.00004100584	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	-0.0338559	0.00825184	0.00004103244	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0400081	0.00975167	0.00004105766	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.0430223	0.0104902	0.0000413237	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	0.0338411	0.00825184	0.00004135212	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0676488	0.0164987	0.00004149375	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0338259	0.00825185	0.00004168272	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.03796	0.00926125	0.00004175423	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03415955	chr3:188028183	3	188028183	LPP	Open sea	0.0338225	0.00825185	0.00004175617	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	-0.128962	0.0314694	0.00004185049	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	0.0338174	0.00825185	0.00004186802	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0572647	0.0139735	0.00004188047	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0343672	0.00838706	0.00004196201	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.025	0.00621	0.000042	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	CPXM1 protein levels (SeqId = 6255-74)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CPXM1 protein levels (SeqId = 6255-74)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable carboxypeptidase X1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000042	None	Gadd-DA_cpxm1_protein_levels__seqid___6255-74__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EFHA1 protein levels (SeqId = 6226-69)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EFHA1 protein levels (SeqId = 6226-69)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium uptake protein 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.208	0.000042	None	Gadd-DA_efha1_protein_levels__seqid___6226-69__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STAT6 protein levels (SeqId = 10372-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STAT6 protein levels (SeqId = 10372-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Signal transducer and activator of transcription 6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.855	0.209	0.000042	None	Gadd-DA_stat6_protein_levels__seqid___10372-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ULBP3 protein levels (SeqId = 2747-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ULBP3 protein levels (SeqId = 2747-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UL16-binding protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000042	None	Gadd-DA_ulbp3_protein_levels__seqid___2747-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AK2 protein levels (SeqId = 11368-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AK2 protein levels (SeqId = 11368-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Adenylate kinase 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000042	None	Gadd-DA_ak2_protein_levels__seqid___11368-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMG3 protein levels (SeqId = 12729-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMG3 protein levels (SeqId = 12729-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Proteasome assembly chaperone 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.208	0.000042	None	Gadd-DA_psmg3_protein_levels__seqid___12729-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MTHFSD protein levels (SeqId = 19129-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MTHFSD protein levels (SeqId = 19129-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Methenyltetrahydrofolate synthase domain-containing protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000042	None	Gadd-DA_mthfsd_protein_levels__seqid___19129-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KCNF1 protein levels (SeqId = 12834-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KCNF1 protein levels (SeqId = 12834-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Potassium voltage-gated channel subfamily F member 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000042	None	Gadd-DA_kcnf1_protein_levels__seqid___12834-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C1orf198 protein levels (SeqId = 8035-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C1orf198 protein levels (SeqId = 8035-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uncharacterized protein C1orf198	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000042	None	Gadd-DA_c1orf198_protein_levels__seqid___8035-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.04359	0.0106392	0.00004206059	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	0.0352184	0.00859611	0.00004207495	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0486259	0.0118696	0.00004213834	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.127095	0.0310298	0.00004223599	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.033799	0.00825185	0.00004227389	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0415827	0.0101526	0.00004230653	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0337942	0.00825186	0.00004237971	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	0.0337905	0.00825186	0.00004246228	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0560879	0.0136986	0.00004254639	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.105761	0.0258321	0.00004255218	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	-0.0347782	0.00849414	0.00004255849	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0337845	0.00825186	0.00004259453	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0337783	0.00825186	0.00004273505	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0356647	0.00871297	0.00004275674	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.0337737	0.00825186	0.00004283686	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0525462	0.0128401	0.00004293136	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	-0.0354253	0.00865672	0.00004295356	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.033768	0.00825186	0.00004296458	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FTL protein levels (SeqId = 15324-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FTL protein levels (SeqId = 15324-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ferritin light chain	774	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-1.28	0.313	0.000043	None	Gadd-DA_ftl_protein_levels__seqid___15324-58__somascan_protein_measurement
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12126519	chr3:188447502	3	188447502	LPP	Open sea	26	6.4	0.000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	TACO1 protein levels (SeqId = 9257-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TACO1 protein levels (SeqId = 9257-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Translational activator of cytochrome c oxidase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000043	None	Gadd-DA_taco1_protein_levels__seqid___9257-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MYL12B protein levels (SeqId = 19122-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYL12B protein levels (SeqId = 19122-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Myosin regulatory light chain 12B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000043	None	Gadd-DA_myl12b_protein_levels__seqid___19122-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PNPO protein levels (SeqId = 17804-102)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PNPO protein levels (SeqId = 17804-102)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pyridoxine-5'-phosphate oxidase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000043	None	Gadd-DA_pnpo_protein_levels__seqid___17804-102__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LGALS8 protein levels (SeqId = 4909-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LGALS8 protein levels (SeqId = 4909-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Galectin-8	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000043	None	Gadd-DA_lgals8_protein_levels__seqid___4909-68__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	0.0337626	0.00825186	0.00004308557	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23493553	chr3:188055123	3	188055123	LPP	Open sea	0.033875	0.00828013	0.00004315972	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0414582	0.0101348	0.00004324164	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0337553	0.00825187	0.00004325041	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0337511	0.00825187	0.00004334647	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0665747	0.0162773	0.0000433598	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	-0.0570297	0.0139465	0.00004352035	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0337412	0.00825187	0.00004357158	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0337354	0.00825187	0.00004370221	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19975917	chr3:188231905	3	188231905	LPP	Open sea	-0.0337321	0.00825187	0.00004377871	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	EIF3J protein levels (SeqId = 13497-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EIF3J protein levels (SeqId = 13497-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Eukaryotic translation initiation factor 3 subunit J	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000044	None	Gadd-DA_eif3j_protein_levels__seqid___13497-34__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TDP1 protein levels (SeqId = 10073-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TDP1 protein levels (SeqId = 10073-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosyl-DNA phosphodiesterase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000044	None	Gadd-DA_tdp1_protein_levels__seqid___10073-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SST protein levels (SeqId = 5957-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SST protein levels (SeqId = 5957-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Somatostatin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000044	None	Gadd-DA_sst_protein_levels__seqid___5957-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SHC1 protein levels (SeqId = 5272-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SHC1 protein levels (SeqId = 5272-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SHC-transforming protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000044	None	Gadd-DA_shc1_protein_levels__seqid___5272-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PABPC3 protein levels (SeqId = 10447-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PABPC3 protein levels (SeqId = 10447-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Polyadenylate-binding protein 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000044	None	Gadd-DA_pabpc3_protein_levels__seqid___10447-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CXADR protein levels (SeqId = 11204-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXADR protein levels (SeqId = 11204-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coxsackievirus and adenovirus receptor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.86	0.209	0.000044	None	Gadd-DA_cxadr_protein_levels__seqid___11204-80__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0337222	0.00825188	0.00004400569	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0337176	0.00825188	0.00004411186	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0523965	0.012824	0.00004415915	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0336981	0.00825188	0.00004456101	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05685023	chr3:187870940	3	187870940	LPP	North shore	-0.0336949	0.00825188	0.00004463746	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	0.0336883	0.00825188	0.00004479052	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MAP1LC3A protein levels (SeqId = 17781-191)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAP1LC3A protein levels (SeqId = 17781-191)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Microtubule-associated proteins 1A/1B light chain 3A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.208	0.000045	None	Gadd-DA_map1lc3a_protein_levels__seqid___17781-191__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CTBP1 protein levels (SeqId = 11217-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CTBP1 protein levels (SeqId = 11217-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-terminal-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000045	None	Gadd-DA_ctbp1_protein_levels__seqid___11217-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	VSIG2 protein levels (SeqId = 8018-43)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VSIG2 protein levels (SeqId = 8018-43)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: V-set and immunoglobulin domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000045	None	Gadd-DA_vsig2_protein_levels__seqid___8018-43__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SMURF1 protein levels (SeqId = 11557-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SMURF1 protein levels (SeqId = 11557-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase SMURF1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.852	0.209	0.000045	None	Gadd-DA_smurf1_protein_levels__seqid___11557-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0336786	0.00825189	0.00004501837	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12314978	chr3:188324556	3	188324556	LPP	Open sea	-0.0336703	0.00825189	0.00004521322	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0691295	0.016943	0.00004524958	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	-0.0336678	0.00825189	0.00004527279	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0336612	0.00825189	0.00004542832	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0336498	0.0082519	0.00004569786	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0362656	0.0088954	0.00004588264	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	UROD protein levels (SeqId = 19289-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UROD protein levels (SeqId = 19289-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uroporphyrinogen decarboxylase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000046	None	Gadd-DA_urod_protein_levels__seqid___19289-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP2R1A protein levels (SeqId = 12621-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP2R1A protein levels (SeqId = 12621-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000046	None	Gadd-DA_ppp2r1a_protein_levels__seqid___12621-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLIC1 protein levels (SeqId = 5013-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLIC1 protein levels (SeqId = 5013-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chloride intracellular channel protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000046	None	Gadd-DA_clic1_protein_levels__seqid___5013-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRAP protein levels (SeqId = 12820-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRAP protein levels (SeqId = 12820-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GRB2-related adapter protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000046	None	Gadd-DA_grap_protein_levels__seqid___12820-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.0430994	0.0105739	0.00004605556	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.052922	0.0129845	0.00004610248	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	0.0336298	0.0082519	0.00004617725	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0439256	0.0107821	0.00004646742	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.0336146	0.00825191	0.00004654424	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	0.0336108	0.00825191	0.00004663599	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15417654	chr3:187959138	3	187959138	LPP	Open sea	0.0352767	0.00866162	0.00004670237	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0336063	0.00825191	0.00004674608	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0336051	0.00825191	0.00004677457	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0492443	0.0120931	0.00004683514	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.0335989	0.00825191	0.00004692503	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SLAMF7 protein levels (SeqId = 5487-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SLAMF7 protein levels (SeqId = 5487-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: SLAM family member 7	774	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.61	0.151	0.000047	None	Gadd-DA_slamf7_protein_levels__seqid___5487-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TXNL4B protein levels (SeqId = 15316-262)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXNL4B protein levels (SeqId = 15316-262)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thioredoxin-like protein 4B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000047	None	Gadd-DA_txnl4b_protein_levels__seqid___15316-262__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCDC134 protein levels (SeqId = 15300-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCDC134 protein levels (SeqId = 15300-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Coiled-coil domain-containing protein 134	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000047	None	Gadd-DA_ccdc134_protein_levels__seqid___15300-66__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPP3CA protein levels (SeqId = 4903-72)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPP3CA protein levels (SeqId = 4903-72)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcineurin subunit B type 1|Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000047	None	Gadd-DA_ppp3ca_protein_levels__seqid___4903-72__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.0335924	0.00825191	0.00004708396	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0335873	0.00825191	0.00004721104	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0335785	0.00825192	0.00004742554	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05230651	chr3:188407110	3	188407110	LPP	Open sea	0.0595435	0.0146369	0.00004765826	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	VIP protein levels (SeqId = 3522-57)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	VIP protein levels (SeqId = 3522-57)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: VIP peptides	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000048	None	Gadd-DA_vip_protein_levels__seqid___3522-57__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FIBP protein levels (SeqId = 19169-88)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FIBP protein levels (SeqId = 19169-88)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acidic fibroblast growth factor intracellular-binding protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000048	None	Gadd-DA_fibp_protein_levels__seqid___19169-88__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FKBP14 protein levels (SeqId = 9340-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FKBP14 protein levels (SeqId = 9340-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase FKBP14	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000048	None	Gadd-DA_fkbp14_protein_levels__seqid___9340-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAP1GDS1 protein levels (SeqId = 14106-46)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAP1GDS1 protein levels (SeqId = 14106-46)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rap1 GTPase-GDP dissociation stimulator 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000048	None	Gadd-DA_rap1gds1_protein_levels__seqid___14106-46__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AGAP2 protein levels (SeqId = 14291-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AGAP2 protein levels (SeqId = 14291-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000048	None	Gadd-DA_agap2_protein_levels__seqid___14291-53__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0335552	0.00825192	0.0000480035	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0335456	0.00825192	0.00004824352	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	-0.0334684	0.00823487	0.00004844237	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01009	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01009	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0335328	0.00825193	0.00004856554	P01009	41361833_Josephine_Robertson_P01009_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.033528	0.00825193	0.0000486883	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0363829	0.00895657	0.00004887626	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2D4 protein levels (SeqId = 13475-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2D4 protein levels (SeqId = 13475-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 D4	774	1	Adults (18-65 years)	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.93	0.229	0.000049	None	Gadd-DA_ube2d4_protein_levels__seqid___13475-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADAMTS13 protein levels (SeqId = 3175-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADAMTS13 protein levels (SeqId = 3175-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: A disintegrin and metalloproteinase with thrombospondin motifs 13	774	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.67	0.16	0.000049	None	Gadd-DA_adamts13_protein_levels__seqid___3175-51__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.025	0.00605	0.000049	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	S100A6 protein levels (SeqId = 13090-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	S100A6 protein levels (SeqId = 13090-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein S100-A6	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000049	None	Gadd-DA_s100a6_protein_levels__seqid___13090-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CYB5R2 protein levels (SeqId = 19143-38)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CYB5R2 protein levels (SeqId = 19143-38)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NADH-cytochrome b5 reductase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000049	None	Gadd-DA_cyb5r2_protein_levels__seqid___19143-38__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CAPNS1 protein levels (SeqId = 18299-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAPNS1 protein levels (SeqId = 18299-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calpain small subunit 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000049	None	Gadd-DA_capns1_protein_levels__seqid___18299-13__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0335098	0.00825193	0.00004915017	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0437625	0.0107773	0.00004920114	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0381735	0.00940115	0.00004921807	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.0335032	0.00825194	0.0000493188	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0335	0.00825194	0.00004940003	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0334995	0.00825194	0.00004941424	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0334989	0.00825194	0.00004942895	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05842762	chr3:188590543	3	188590543	LPP	Open sea	0.168836	0.0415928	0.00004944352	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0398847	0.00982609	0.00004952639	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0355449	0.00876104	0.00004993044	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0367668	0.00906256	0.00004996562	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Osteoarthritis (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Osteoarthritis (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18060	1	Adults (18-65y)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.093	0.023	0.00005	None	Robert-F-Hillary_Prevalent_Osteoarthritis_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	BTN3A3 protein levels (SeqId = 17692-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BTN3A3 protein levels (SeqId = 17692-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Butyrophilin subfamily 3 member A3	774	1	Adults (18-65 years)	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.47	0.115	0.00005	None	Gadd-DA_btn3a3_protein_levels__seqid___17692-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LDHB protein levels (SeqId = 3890-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LDHB protein levels (SeqId = 3890-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: L-lactate dehydrogenase B chain	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.00005	None	Gadd-DA_ldhb_protein_levels__seqid___3890-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CNOT1 protein levels (SeqId = 13482-14)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CNOT1 protein levels (SeqId = 13482-14)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: CCR4-NOT transcription complex subunit 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.208	0.00005	None	Gadd-DA_cnot1_protein_levels__seqid___13482-14__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB5C protein levels (SeqId = 14287-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB5C protein levels (SeqId = 14287-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-5C	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.00005	None	Gadd-DA_rab5c_protein_levels__seqid___14287-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CS protein levels (SeqId = 18309-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CS protein levels (SeqId = 18309-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Citrate synthase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.00005	None	Gadd-DA_cs_protein_levels__seqid___18309-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TIMM8A protein levels (SeqId = 19148-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TIMM8A protein levels (SeqId = 19148-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitochondrial import inner membrane translocase subunit Tim8 A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.00005	None	Gadd-DA_timm8a_protein_levels__seqid___19148-58__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0334613	0.00825195	0.00005040217	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.042292	0.0104301	0.00005043332	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Battram T	GEO	23177740	2020-09-15	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Whole blood	None	656	1	Adults	Both	Unclear	cg07196133	chr3:188439649	3	188439649	LPP	Open sea	0.00024	0.000059	0.000051	None	23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279
Gadd DA	Generation Scotland	35945220	31/07/2022	PGR protein levels (SeqId = 15693-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGR protein levels (SeqId = 15693-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Progesterone receptor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000051	None	Gadd-DA_pgr_protein_levels__seqid___15693-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FCAMR protein levels (SeqId = 9568-289)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FCAMR protein levels (SeqId = 9568-289)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.21	0.000051	None	Gadd-DA_fcamr_protein_levels__seqid___9568-289__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BCAT2 protein levels (SeqId = 19365-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BCAT2 protein levels (SeqId = 19365-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Branched-chain-amino-acid aminotransferase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000051	None	Gadd-DA_bcat2_protein_levels__seqid___19365-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EDC4 protein levels (SeqId = 13066-42)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EDC4 protein levels (SeqId = 13066-42)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Enhancer of mRNA-decapping protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000051	None	Gadd-DA_edc4_protein_levels__seqid___13066-42__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRB14 protein levels (SeqId = 13628-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRB14 protein levels (SeqId = 13628-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Growth factor receptor-bound protein 14	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000051	None	Gadd-DA_grb14_protein_levels__seqid___13628-58__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ATP5O protein levels (SeqId = 9202-309)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ATP5O protein levels (SeqId = 9202-309)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ATP synthase subunit O, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000051	None	Gadd-DA_atp5o_protein_levels__seqid___9202-309__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MTHFD2 protein levels (SeqId = 18321-38)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MTHFD2 protein levels (SeqId = 18321-38)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.843	0.208	0.000051	None	Gadd-DA_mthfd2_protein_levels__seqid___18321-38__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.04379	0.0108083	0.00005115029	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01344	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01344	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0450372	0.0111176	0.00005126396	P01344	41361833_Josephine_Robertson_P01344_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0415898	0.0102669	0.00005129509	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0396235	0.00978287	0.00005141687	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0334216	0.00825196	0.00005144918	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.03342	0.00825196	0.00005149253	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0375026	0.00926024	0.00005151347	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0378635	0.00935221	0.00005178733	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	MANSC1 protein levels (SeqId = 9557-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MANSC1 protein levels (SeqId = 9557-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MANSC domain-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg02716749	chr3:187871801	3	187871801	LPP	Island	-0.71	0.174	0.000052	None	Gadd-DA_mansc1_protein_levels__seqid___9557-5__somascan_protein_measurement
Neumann A	ALSPAC, GENR, INMA, NEST, PREDO	33184255	2020-11-12	ADHD	EFO_0003888	At birth	Supplementary data adhd_birth_results	ADHD	DNA methylation	maternal age, education level, smoking, gestational age, sex, cell composition (reference based)	ADHD score	Beta Values	Illumina HumanMethylation450	Cord Blood	None	2477	5	Infants	Both	European, African	cg19756112	chr3:188200427	3	188200427	LPP	Open sea	-1.799	0.573	0.000052	None	33184255_Neumann-A_adhd_at_birth
Gadd DA	Generation Scotland	35945220	31/07/2022	ITPKA protein levels (SeqId = 13473-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ITPKA protein levels (SeqId = 13473-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inositol-trisphosphate 3-kinase A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.21	0.000052	None	Gadd-DA_itpka_protein_levels__seqid___13473-55__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDM1 protein levels (SeqId = 7898-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDM1 protein levels (SeqId = 7898-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Nuclear protein MDM1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.847	0.209	0.000052	None	Gadd-DA_mdm1_protein_levels__seqid___7898-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PPIL1 protein levels (SeqId = 9884-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPIL1 protein levels (SeqId = 9884-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peptidyl-prolyl cis-trans isomerase-like 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000052	None	Gadd-DA_ppil1_protein_levels__seqid___9884-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNRPA protein levels (SeqId = 12678-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNRPA protein levels (SeqId = 12678-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: U1 small nuclear ribonucleoprotein A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000052	None	Gadd-DA_snrpa_protein_levels__seqid___12678-66__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPRE2 protein levels (SeqId = 16856-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPRE2 protein levels (SeqId = 16856-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Microtubule-associated protein RP/EB family member 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000052	None	Gadd-DA_mapre2_protein_levels__seqid___16856-79__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0399166	0.00986233	0.00005206101	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q16610	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q16610	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0450006	0.0111189	0.00005209466	Q16610	41361833_Josephine_Robertson_Q16610_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0616399	0.0152307	0.00005212323	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg12120178	chr3:188103284	3	188103284	LPP	Open sea	-0.1209539	0.0298966	0.00005216	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0362041	0.00894645	0.00005219872	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05984281	chr3:188413418	3	188413418	LPP	Open sea	-0.0333902	0.00825197	0.00005229404	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0333891	0.00825197	0.0000523234	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0333845	0.00825197	0.0000524468	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0369139	0.00912501	0.00005251081	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0359307	0.00888391	0.00005271101	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.0365904	0.00904711	0.00005271873	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0434871	0.0107527	0.00005275104	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	0.0333714	0.00825197	0.00005280532	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0373814	0.00924379	0.00005282812	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	PGK1 protein levels (SeqId = 5020-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGK1 protein levels (SeqId = 5020-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphoglycerate kinase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000053	None	Gadd-DA_pgk1_protein_levels__seqid___5020-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FH protein levels (SeqId = 13384-110)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FH protein levels (SeqId = 13384-110)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fumarate hydratase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.845	0.209	0.000053	None	Gadd-DA_fh_protein_levels__seqid___13384-110__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	0.0389478	0.00963548	0.00005324121	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0333523	0.00825198	0.00005332753	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0333442	0.00825198	0.00005355099	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0664392	0.0164462	0.00005376921	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0434956	0.0107672	0.00005380548	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	PGLYRP2 protein levels (SeqId = 5601-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGLYRP2 protein levels (SeqId = 5601-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-acetylmuramoyl-L-alanine amidase	774	1	Adults (18-65 years)	Both	European	cg21779805	chr3:187982495	3	187982495	LPP	Open sea	0.68	0.168	0.000054	None	Gadd-DA_pglyrp2_protein_levels__seqid___5601-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB1A protein levels (SeqId = 19223-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB1A protein levels (SeqId = 19223-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-1A	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.85	0.209	0.000054	None	Gadd-DA_rab1a_protein_levels__seqid___19223-6__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.440938	0.1092	0.0000544	None	27105112_hiv_infection_cd4_tcells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0333094	0.00825199	0.0000545232	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.033309	0.00825199	0.00005453353	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0333083	0.00825199	0.00005455341	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12314978	chr3:188324556	3	188324556	LPP	Open sea	0.0333059	0.00825199	0.00005462076	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.150185	0.0372147	0.00005467742	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	0.0481785	0.0119385	0.00005475175	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	0.0520089	0.0128902	0.00005493241	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26124569	chr3:187975150	3	187975150	LPP	Open sea	0.0017	None	0.000055	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	IRAK4 protein levels (SeqId = 18162-167)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IRAK4 protein levels (SeqId = 18162-167)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-1 receptor-associated kinase 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000055	None	Gadd-DA_irak4_protein_levels__seqid___18162-167__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CAMK1 protein levels (SeqId = 3592-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAMK1 protein levels (SeqId = 3592-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcium/calmodulin-dependent protein kinase type 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000055	None	Gadd-DA_camk1_protein_levels__seqid___3592-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TBPL1 protein levels (SeqId = 18434-141)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TBPL1 protein levels (SeqId = 18434-141)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: TATA box-binding protein-like protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000055	None	Gadd-DA_tbpl1_protein_levels__seqid___18434-141__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	UXS1 protein levels (SeqId = 8258-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UXS1 protein levels (SeqId = 8258-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UDP-glucuronic acid decarboxylase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000055	None	Gadd-DA_uxs1_protein_levels__seqid___8258-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCL28 protein levels (SeqId = 2890-59)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCL28 protein levels (SeqId = 2890-59)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-C motif chemokine 28	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.208	0.000055	None	Gadd-DA_ccl28_protein_levels__seqid___2890-59__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	AP1S2 protein levels (SeqId = 18405-117)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AP1S2 protein levels (SeqId = 18405-117)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: AP-1 complex subunit sigma-2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000055	None	Gadd-DA_ap1s2_protein_levels__seqid___18405-117__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0654984	0.0162349	0.00005501715	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	0.0358681	0.00889485	0.00005547753	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	0.0345781	0.00857525	0.00005551006	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.105666	0.0262079	0.00005556424	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.0332727	0.008252	0.00005556569	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	-0.0332713	0.008252	0.00005560434	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Liu C	CHARGE+	27843151	2016-12-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	European ancestry	Table S5	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g der day	Illumina HumanMethylation450	Whole blood	-	9643	10	64.2	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.00013755	3.41e-05	0.0000559	-	27843151_alcohol_consumption_per_day_european_ancestry
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.006	None	0.000056	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	ARHGAP1 protein levels (SeqId = 11955-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARHGAP1 protein levels (SeqId = 11955-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Rho GTPase-activating protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000056	None	Gadd-DA_arhgap1_protein_levels__seqid___11955-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDE5A protein levels (SeqId = 5256-86)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDE5A protein levels (SeqId = 5256-86)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: cGMP-specific 3',5'-cyclic phosphodiesterase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000056	None	Gadd-DA_pde5a_protein_levels__seqid___5256-86__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRDM4 protein levels (SeqId = 12779-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRDM4 protein levels (SeqId = 12779-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: PR domain zinc finger protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000056	None	Gadd-DA_prdm4_protein_levels__seqid___12779-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PSMD4 protein levels (SeqId = 13568-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSMD4 protein levels (SeqId = 13568-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 26S proteasome non-ATPase regulatory subunit 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000056	None	Gadd-DA_psmd4_protein_levels__seqid___13568-30__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.033252	0.00825201	0.00005616168	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	0.0332519	0.00825201	0.00005616382	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	0.0332464	0.00825201	0.00005632474	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19198938	chr3:188001192	3	188001192	LPP	Open sea	0.033246	0.00825201	0.00005633526	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0511547	0.0126996	0.00005652252	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.0332321	0.00825201	0.00005674108	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	-0.17822	0.0442612	0.00005683057	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	0.0332266	0.00825201	0.00005690051	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	-0.0332186	0.00825201	0.00005713677	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.033215	0.00825202	0.00005724345	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0332006	0.00825202	0.00005766859	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	-0.0331951	0.00825202	0.00005783105	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	CCK protein levels (SeqId = 6918-183)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCK protein levels (SeqId = 6918-183)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cholecystokinin	774	1	Adults (18-65 years)	Both	European	cg13593629	chr3:188443109	3	188443109	LPP	Open sea	-0.468	0.116	0.000058	None	Gadd-DA_cck_protein_levels__seqid___6918-183__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCL5 protein levels (SeqId = 5480-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCL5 protein levels (SeqId = 5480-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-C motif chemokine 5	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000058	None	Gadd-DA_ccl5_protein_levels__seqid___5480-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DLG2 protein levels (SeqId = 19620-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DLG2 protein levels (SeqId = 19620-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Disks large homolog 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000058	None	Gadd-DA_dlg2_protein_levels__seqid___19620-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DUT protein levels (SeqId = 9995-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DUT protein levels (SeqId = 9995-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000058	None	Gadd-DA_dut_protein_levels__seqid___9995-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0395813	0.00984232	0.00005810859	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg14932952	chr3:187943282	3	187943282	LPP	Open sea	-0.125589	0.0312318	0.00005814304	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0331812	0.00825203	0.00005824589	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0613228	0.0152519	0.00005832404	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05048043	chr3:188198457	3	188198457	LPP	Open sea	-0.0388682	0.00966728	0.00005834292	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.033164	0.00825203	0.00005876532	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0421925	0.0104988	0.00005879164	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Ischemic Heart Disease (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Ischemic Heart Disease (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18059	1	Adults (18-65y)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.07	0.0174	0.000059	None	Robert-F-Hillary_Prevalent_Ischemic_Heart_Disease_(Self-report)_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	SPINT2 protein levels (SeqId = 2843-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPINT2 protein levels (SeqId = 2843-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kunitz-type protease inhibitor 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000059	None	Gadd-DA_spint2_protein_levels__seqid___2843-13__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FATE1 protein levels (SeqId = 7740-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FATE1 protein levels (SeqId = 7740-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fetal and adult testis-expressed transcript protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000059	None	Gadd-DA_fate1_protein_levels__seqid___7740-33__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PGRMC2 protein levels (SeqId = 10506-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PGRMC2 protein levels (SeqId = 10506-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Membrane-associated progesterone receptor component 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000059	None	Gadd-DA_pgrmc2_protein_levels__seqid___10506-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAD51L3 protein levels (SeqId = 12554-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAD51L3 protein levels (SeqId = 12554-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA repair protein RAD51 homolog 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000059	None	Gadd-DA_rad51l3_protein_levels__seqid___12554-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MAPKAPK5 protein levels (SeqId = 3821-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAPKAPK5 protein levels (SeqId = 3821-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAP kinase-activated protein kinase 5	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000059	None	Gadd-DA_mapkapk5_protein_levels__seqid___3821-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.0331425	0.00825204	0.00005941907	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0331411	0.00825204	0.00005946188	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0390424	0.00972253	0.00005957512	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0331278	0.00825204	0.00005986856	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0444042	0.0110611	0.00005987795	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	KIAA0040 protein levels (SeqId = 14603-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIAA0040 protein levels (SeqId = 14603-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uncharacterized protein KIAA0040	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.00006	None	Gadd-DA_kiaa0040_protein_levels__seqid___14603-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	BDNF protein levels (SeqId = 2421-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BDNF protein levels (SeqId = 2421-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Brain-derived neurotrophic factor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.837	0.209	0.00006	None	Gadd-DA_bdnf_protein_levels__seqid___2421-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MYDGF protein levels (SeqId = 9248-36)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYDGF protein levels (SeqId = 9248-36)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Myeloid-derived growth factor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.00006	None	Gadd-DA_mydgf_protein_levels__seqid___9248-36__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRDX5 protein levels (SeqId = 5017-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRDX5 protein levels (SeqId = 5017-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxiredoxin-5, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.00006	None	Gadd-DA_prdx5_protein_levels__seqid___5017-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0364273	0.00907597	0.00006009741	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.0331183	0.00825204	0.00006016183	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.0530071	0.0132093	0.0000602844	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.0331131	0.00825204	0.00006032381	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	0.0386453	0.0096325	0.00006051188	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0566257	0.014115	0.0000605726	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0469024	0.0116926	0.00006069122	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0419014	0.0104463	0.00006072724	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0390002	0.00972334	0.000060764	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CTHRC1 protein levels (SeqId = 15467-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CTHRC1 protein levels (SeqId = 15467-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen triple helix repeat-containing protein 1	774	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	0.71	0.176	0.000061	None	Gadd-DA_cthrc1_protein_levels__seqid___15467-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ETHE1 protein levels (SeqId = 3847-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ETHE1 protein levels (SeqId = 3847-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Persulfide dioxygenase ETHE1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000061	None	Gadd-DA_ethe1_protein_levels__seqid___3847-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TXLNA protein levels (SeqId = 15698-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TXLNA protein levels (SeqId = 15698-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-taxilin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000061	None	Gadd-DA_txlna_protein_levels__seqid___15698-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0392245	0.00978163	0.00006101513	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0638793	0.0159333	0.00006123698	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23108188	chr3:188080604	3	188080604	LPP	Open sea	-0.0330817	0.00825205	0.00006130271	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.0337378	0.00841596	0.00006133425	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0330732	0.00825205	0.00006156923	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0330723	0.00825205	0.00006159883	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0330714	0.00825206	0.00006162789	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0527111	0.0131552	0.00006183524	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	GZMA protein levels (SeqId = 3440-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GZMA protein levels (SeqId = 3440-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Granzyme A	774	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.81	0.203	0.000062	None	Gadd-DA_gzma_protein_levels__seqid___3440-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAMP3 protein levels (SeqId = 15437-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAMP3 protein levels (SeqId = 15437-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Receptor activity-modifying protein 3	774	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.97	0.241	0.000062	None	Gadd-DA_ramp3_protein_levels__seqid___15437-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SYK protein levels (SeqId = 11378-37)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SYK protein levels (SeqId = 11378-37)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase SYK	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000062	None	Gadd-DA_syk_protein_levels__seqid___11378-37__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6I0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0358445	0.00894916	0.00006223062	A0A075B6I0	41361833_Josephine_Robertson_A0A075B6I0_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.0330513	0.00825206	0.00006226482	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg01683373	chr3:187916442	3	187916442	LPP	Open sea	-0.176834	0.0441558	0.00006232431	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0391324	0.009772	0.00006244405	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0411604	0.0102784	0.0000624465	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.0359994	0.00898981	0.00006246468	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	-0.033045	0.00825206	0.00006246782	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0330437	0.00825206	0.00006250745	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.0330432	0.00825206	0.00006252337	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0545368	0.0136202	0.00006255694	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0429075	0.0107196	0.00006293032	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0388811	0.00971424	0.00006298894	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04952622	chr3:188067331	3	188067331	LPP	Open sea	0.01232	0.00301	0.000063	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	APCS protein levels (SeqId = 2474-54)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APCS protein levels (SeqId = 2474-54)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serum amyloid P-component	774	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.56	0.14	0.000063	None	Gadd-DA_apcs_protein_levels__seqid___2474-54__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NOG protein levels (SeqId = 8778-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NOG protein levels (SeqId = 8778-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Noggin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.837	0.209	0.000063	None	Gadd-DA_nog_protein_levels__seqid___8778-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COL2A1 protein levels (SeqId = 18875-125)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COL2A1 protein levels (SeqId = 18875-125)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen alpha-1(II) chain	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.205	0.000063	None	Gadd-DA_col2a1_protein_levels__seqid___18875-125__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CHFR protein levels (SeqId = 11320-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHFR protein levels (SeqId = 11320-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase CHFR	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000063	None	Gadd-DA_chfr_protein_levels__seqid___11320-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PTP4A3 protein levels (SeqId = 19231-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTP4A3 protein levels (SeqId = 19231-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein tyrosine phosphatase type IVA 3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000063	None	Gadd-DA_ptp4a3_protein_levels__seqid___19231-22__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LCK protein levels (SeqId = 4560-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LCK protein levels (SeqId = 4560-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tyrosine-protein kinase Lck	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000063	None	Gadd-DA_lck_protein_levels__seqid___4560-34__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0330243	0.00825207	0.00006313425	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.033023	0.00825207	0.00006317665	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02123607	chr3:188301222	3	188301222	LPP	Open sea	-0.0357527	0.00893451	0.00006321246	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	-0.0897339	0.0224266	0.00006326266	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0395369	0.00988257	0.00006347309	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0330132	0.00825207	0.00006349229	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	-0.0389502	0.00973687	0.00006357773	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	IGHM protein levels (SeqId = 3069-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IGHM protein levels (SeqId = 3069-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin heavy constant mu	774	1	Adults (18-65 years)	Both	European	cg10671125	chr3:188401518	3	188401518	LPP	Open sea	0.31	0.077	0.000064	None	Gadd-DA_ighm_protein_levels__seqid___3069-52__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FTH1 protein levels (SeqId = 5934-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FTH1 protein levels (SeqId = 5934-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ferritin heavy chain|Ferritin light chain	774	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.69	0.172	0.000064	None	Gadd-DA_fth1_protein_levels__seqid___5934-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	POLR2K protein levels (SeqId = 19134-66)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	POLR2K protein levels (SeqId = 19134-66)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA-directed RNA polymerases I, II, and III subunit RPABC4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000064	None	Gadd-DA_polr2k_protein_levels__seqid___19134-66__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0329973	0.00825208	0.00006401185	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.163167	0.0408152	0.00006421295	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22480993	chr3:187943102	3	187943102	LPP	Open sea	0.130818	0.0327234	0.00006422892	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	-0.0329893	0.00825208	0.00006427625	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	-0.0439309	0.0109895	0.00006432201	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07196133	chr3:188439649	3	188439649	LPP	Open sea	-0.0329822	0.00825208	0.00006450955	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0329788	0.00825208	0.00006462258	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0362046	0.00906012	0.00006472565	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	-0.0329741	0.00825208	0.0000647768	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	LY9 protein levels (SeqId = 3324-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LY9 protein levels (SeqId = 3324-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: T-lymphocyte surface antigen Ly-9	774	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.41	0.102	0.000065	None	Gadd-DA_ly9_protein_levels__seqid___3324-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SNAP29 protein levels (SeqId = 12357-41)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SNAP29 protein levels (SeqId = 12357-41)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Synaptosomal-associated protein 29	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.208	0.000065	None	Gadd-DA_snap29_protein_levels__seqid___12357-41__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CRYBB1 protein levels (SeqId = 17751-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRYBB1 protein levels (SeqId = 17751-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-crystallin B1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000065	None	Gadd-DA_crybb1_protein_levels__seqid___17751-68__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PTGES2 protein levels (SeqId = 18458-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTGES2 protein levels (SeqId = 18458-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prostaglandin E synthase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000065	None	Gadd-DA_ptges2_protein_levels__seqid___18458-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	D6RF35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	D6RF35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0459869	0.0115111	0.00006501371	D6RF35	41361833_Josephine_Robertson_D6RF35_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0329655	0.00825208	0.0000650628	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0329654	0.00825208	0.00006506552	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0496184	0.0124243	0.00006537974	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03945529	chr3:188024721	3	188024721	LPP	Open sea	0.0329542	0.00825209	0.0000654396	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01009	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01009	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.032947	0.00825209	0.00006568032	P01009	41361833_Josephine_Robertson_P01009_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.0529882	0.0132722	0.00006572502	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0329383	0.00825209	0.00006597246	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PLEKHA4 protein levels (SeqId = 10939-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLEKHA4 protein levels (SeqId = 10939-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pleckstrin homology domain-containing family A member 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000066	None	Gadd-DA_plekha4_protein_levels__seqid___10939-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PRKAR2A protein levels (SeqId = 19125-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PRKAR2A protein levels (SeqId = 19125-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: cAMP-dependent protein kinase type II-alpha regulatory subunit	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000066	None	Gadd-DA_prkar2a_protein_levels__seqid___19125-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HNRNPDL protein levels (SeqId = 10852-114)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HNRNPDL protein levels (SeqId = 10852-114)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Heterogeneous nuclear ribonucleoprotein D-like	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.84	0.209	0.000066	None	Gadd-DA_hnrnpdl_protein_levels__seqid___10852-114__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CSMD2 protein levels (SeqId = 9971-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSMD2 protein levels (SeqId = 9971-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: CUB and sushi domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000066	None	Gadd-DA_csmd2_protein_levels__seqid___9971-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.0329361	0.00825209	0.00006604668	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0329355	0.00825209	0.00006606906	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	0.0329329	0.00825209	0.00006615592	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02579706	chr3:187960622	3	187960622	LPP	Open sea	-0.0329326	0.00825209	0.00006616438	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0329325	0.00825209	0.00006616963	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0329304	0.00825209	0.00006624028	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0346219	0.00867704	0.00006637829	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03548412	chr3:188063126	3	188063126	LPP	Open sea	-0.033296	0.00834501	0.00006641456	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.0361847	0.00906945	0.00006646773	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	0.032916	0.0082521	0.00006673062	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	0.075427	0.0189146	0.00006697266	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.01	0.0025	0.000067	None	33450751_Mulder-RH_sex_discovery
Anna Ulrich	None	38184627	Dec 5, 2023	Idiopathic/heritable pulmonary arterial hypertension	None	Discovery	None	DNA methylation	Idiopathic/heritable pulmonary arterial hypertension	Age, Sex, Smoking, Cell composition (reference based), Ancestry (other), first ten principal components computed from control probes	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	1655	4	Adults	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	12	3.1	0.000067	None	38184627_Anna-Ulrich_idiopathic_heritable_pulmonary_arterial_hypertension_discovery
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.88	0.22	0.000067	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	DPY30 protein levels (SeqId = 13943-38)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPY30 protein levels (SeqId = 13943-38)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein dpy-30 homolog	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000067	None	Gadd-DA_dpy30_protein_levels__seqid___13943-38__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ASMTL protein levels (SeqId = 10089-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASMTL protein levels (SeqId = 10089-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000067	None	Gadd-DA_asmtl_protein_levels__seqid___10089-7__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	CD4+ T-cells	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	CD4+ T-cells	-	60	1	46.5	Males	European	cg18188653	chr3:188296976	3	188296976	LPP	Open sea	-0.209351	0.0525	0.0000672	None	27105112_hiv_infection_cd4_tcells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16464007	chr3:188002729	3	188002729	LPP	Open sea	0.180406	0.0452505	0.0000672375	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-0.032895	0.0082521	0.00006744849	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.0551575	0.0138369	0.00006745052	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg17079738	chr3:187882141	3	187882141	LPP	Open sea	-0.151215	0.0379395	0.00006754644	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0427263	0.0107203	0.00006764587	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0426776	0.0107082	0.00006766527	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23235460	chr3:187871625	3	187871625	LPP	Island	-0.038441	0.00964569	0.00006772147	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.0328852	0.00825211	0.0000677863	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.107434	0.0269651	0.00006797713	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08158324	chr3:188150137	3	188150137	LPP	Open sea	0.013	0.0032	0.000068	None	33450751_Mulder-RH_sex_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12120430	chr3:187935971	3	187935971	LPP	Open sea	0.00745	0.00183	0.000068	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16915803	chr3:187909561	3	187909561	LPP	Open sea	0.0054	0.0013	0.000068	None	33450751_Mulder-RH_sex_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	MPL protein levels (SeqId = 3473-78)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MPL protein levels (SeqId = 3473-78)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thrombopoietin receptor	774	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.95	0.238	0.000068	None	Gadd-DA_mpl_protein_levels__seqid___3473-78__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TAPBP protein levels (SeqId = 12378-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TAPBP protein levels (SeqId = 12378-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tapasin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000068	None	Gadd-DA_tapbp_protein_levels__seqid___12378-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NLGN3 protein levels (SeqId = 8941-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NLGN3 protein levels (SeqId = 8941-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Neuroligin-3	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000068	None	Gadd-DA_nlgn3_protein_levels__seqid___8941-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACOT8 protein levels (SeqId = 17400-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACOT8 protein levels (SeqId = 17400-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-coenzyme A thioesterase 8	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.834	0.209	0.000068	None	Gadd-DA_acot8_protein_levels__seqid___17400-71__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0423397	0.0106269	0.00006803392	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23235460	chr3:187871625	3	187871625	LPP	Island	0.0328757	0.00825211	0.00006811527	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.036947	0.00927563	0.00006831227	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	-0.0328662	0.00825211	0.00006844821	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0399023	0.0100189	0.00006846547	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21838354	chr3:188389911	3	188389911	LPP	Open sea	-0.0328607	0.00825211	0.00006863841	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.0328557	0.00825211	0.00006881445	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0428498	0.0107624	0.00006883065	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	-0.0328545	0.00825211	0.00006885598	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	-0.032852	0.00825211	0.00006894445	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TSLP protein levels (SeqId = 3010-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TSLP protein levels (SeqId = 3010-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thymic stromal lymphopoietin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000069	None	Gadd-DA_tslp_protein_levels__seqid___3010-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NMT1 protein levels (SeqId = 5196-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NMT1 protein levels (SeqId = 5196-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycylpeptide N-tetradecanoyltransferase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000069	None	Gadd-DA_nmt1_protein_levels__seqid___5196-7__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg23070717	chr3:187947254	3	187947254	LPP	Open sea	0.0997655	0.0250683	0.00006925681	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	0.0330783	0.00831186	0.00006934823	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	-0.0333333	0.00837613	0.00006937616	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	0.0328345	0.00825212	0.00006956154	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.0328345	0.00825212	0.00006956228	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0373754	0.00939364	0.00006959789	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.159205	0.0400156	0.00006961053	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0328284	0.00825212	0.00006978033	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0328271	0.00825212	0.00006982619	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.032823	0.00825212	0.00006997103	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFRSF17 protein levels (SeqId = 2665-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFRSF17 protein levels (SeqId = 2665-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor receptor superfamily member 17	774	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.77	0.193	0.00007	None	Gadd-DA_tnfrsf17_protein_levels__seqid___2665-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NXT1 protein levels (SeqId = 9942-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NXT1 protein levels (SeqId = 9942-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NTF2-related export protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.00007	None	Gadd-DA_nxt1_protein_levels__seqid___9942-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ANGPT4 protein levels (SeqId = 2500-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ANGPT4 protein levels (SeqId = 2500-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Angiopoietin-4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.832	0.209	0.00007	None	Gadd-DA_angpt4_protein_levels__seqid___2500-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KIF23 protein levels (SeqId = 5228-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIF23 protein levels (SeqId = 5228-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kinesin-like protein KIF23	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.00007	None	Gadd-DA_kif23_protein_levels__seqid___5228-25__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0367258	0.00923412	0.00007007057	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03285705	chr3:188260652	3	188260652	LPP	Open sea	-0.0328197	0.00825212	0.00007008854	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.032818	0.00825212	0.00007015007	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0399785	0.0100559	0.00007052618	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	0.0388453	0.00977121	0.00007057155	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20893542	chr3:187929286	3	187929286	LPP	Open sea	-0.0328049	0.00825213	0.00007061979	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	0.0383953	0.00966005	0.00007082205	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	JUND protein levels (SeqId = 19602-36)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	JUND protein levels (SeqId = 19602-36)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription factor jun-D	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000071	None	Gadd-DA_jund_protein_levels__seqid___19602-36__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARFIP1 protein levels (SeqId = 13488-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARFIP1 protein levels (SeqId = 13488-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Arfaptin-1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.208	0.000071	None	Gadd-DA_arfip1_protein_levels__seqid___13488-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0428246	0.0107762	0.00007101063	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0327901	0.00825213	0.00007115436	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	-0.0372386	0.00937283	0.00007130104	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.0327731	0.00825214	0.0000717706	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0327668	0.00825214	0.0000720039	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02012933	chr3:187990265	3	187990265	LPP	Open sea	0.0402648	0.0101406	0.00007202318	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0605546	0.0152518	0.00007211867	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04441577	chr3:188429875	3	188429875	LPP	Open sea	0.032759	0.00825214	0.00007229011	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0427584	0.0107725	0.0000724536	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	0.0327517	0.00825214	0.00007255582	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05984281	chr3:188413418	3	188413418	LPP	Open sea	0.0327446	0.00825214	0.00007281954	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0552681	0.0139288	0.00007284965	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0327401	0.00825215	0.00007298572	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14391	1	Adults (18-65y)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.2	0.0492	0.000073	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Fully-adjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	C6 protein levels (SeqId = 4127-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C6 protein levels (SeqId = 4127-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Complement component C6	774	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.55	0.139	0.000073	None	Gadd-DA_c6_protein_levels__seqid___4127-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TCEA2 protein levels (SeqId = 13481-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TCEA2 protein levels (SeqId = 13481-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transcription elongation factor A protein 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.826	0.208	0.000073	None	Gadd-DA_tcea2_protein_levels__seqid___13481-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ADAMDEC1 protein levels (SeqId = 9115-78)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ADAMDEC1 protein levels (SeqId = 9115-78)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADAM DEC1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000073	None	Gadd-DA_adamdec1_protein_levels__seqid___9115-78__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STUB1 protein levels (SeqId = 11350-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STUB1 protein levels (SeqId = 11350-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase CHIP	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000073	None	Gadd-DA_stub1_protein_levels__seqid___11350-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TMEM59L protein levels (SeqId = 9959-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMEM59L protein levels (SeqId = 9959-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Transmembrane protein 59-like	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000073	None	Gadd-DA_tmem59l_protein_levels__seqid___9959-60__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0327307	0.00825215	0.00007333544	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0371424	0.00936499	0.00007340751	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0429033	0.0108175	0.00007340879	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	0.0327252	0.00825215	0.00007354291	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0327237	0.00825215	0.00007359918	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FUT8 protein levels (SeqId = 8244-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FUT8 protein levels (SeqId = 8244-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-(1,6)-fucosyltransferase	774	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.55	0.139	0.000074	None	Gadd-DA_fut8_protein_levels__seqid___8244-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARFGAP1 protein levels (SeqId = 11556-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARFGAP1 protein levels (SeqId = 11556-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor GTPase-activating protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000074	None	Gadd-DA_arfgap1_protein_levels__seqid___11556-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ENO2 protein levels (SeqId = 10339-48)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ENO2 protein levels (SeqId = 10339-48)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gamma-enolase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000074	None	Gadd-DA_eno2_protein_levels__seqid___10339-48__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0327098	0.00825215	0.00007412024	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13714834	chr3:188135135	3	188135135	LPP	Open sea	-0.0389833	0.0098351	0.00007415077	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	-0.0327082	0.00825215	0.00007418	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	-0.0327052	0.00825215	0.00007429095	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0474719	0.0119816	0.00007466104	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.0517586	0.0130668	0.00007496395	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Battram T	GEO	30291105	2020-11-01	Age	EFO_0000246	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE113904	None	DNA methylation	Age	Batch effects, cell composition (reference free)	Beta Values	Years	Illumina HumanMethylation450	Colon, rectum	None	232	1	Adults	Both	Unclear	cg08158324	chr3:188150137	3	188150137	LPP	Open sea	0.00055	0.00014	0.000075	None	30291105_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse113904
Gadd DA	Generation Scotland	35945220	31/07/2022	FTL protein levels (SeqId = 15324-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FTL protein levels (SeqId = 15324-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ferritin light chain	774	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.68	0.172	0.000075	None	Gadd-DA_ftl_protein_levels__seqid___15324-58__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MPL protein levels (SeqId = 3473-78)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MPL protein levels (SeqId = 3473-78)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Thrombopoietin receptor	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000075	None	Gadd-DA_mpl_protein_levels__seqid___3473-78__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C12orf10 protein levels (SeqId = 8303-102)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C12orf10 protein levels (SeqId = 8303-102)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UPF0160 protein MYG1, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000075	None	Gadd-DA_c12orf10_protein_levels__seqid___8303-102__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CBL protein levels (SeqId = 12016-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CBL protein levels (SeqId = 12016-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase CBL	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.208	0.000075	None	Gadd-DA_cbl_protein_levels__seqid___12016-60__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.0326829	0.00825216	0.00007513879	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0326827	0.00825216	0.00007514605	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04535966	chr3:188034983	3	188034983	LPP	Open sea	-0.0326755	0.00825216	0.00007541952	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0326734	0.00825216	0.00007550264	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	-0.143879	0.0363455	0.00007566159	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07946345	chr3:188276773	3	188276773	LPP	Open sea	0.0341918	0.00863694	0.00007568832	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0326683	0.00825216	0.00007569502	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14091103	chr3:187870929	3	187870929	LPP	North shore	-0.0326661	0.00825217	0.00007578127	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.174409	0.0440675	0.00007595862	None	39706196_Hannah-M.-Smith_body_fat_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	S100A5 protein levels (SeqId = 15303-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	S100A5 protein levels (SeqId = 15303-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein S100-A5	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000076	None	Gadd-DA_s100a5_protein_levels__seqid___15303-63__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CA13 protein levels (SeqId = 3420-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CA13 protein levels (SeqId = 3420-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Carbonic anhydrase 13	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000076	None	Gadd-DA_ca13_protein_levels__seqid___3420-21__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RBM17 protein levels (SeqId = 17391-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RBM17 protein levels (SeqId = 17391-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Splicing factor 45	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000076	None	Gadd-DA_rbm17_protein_levels__seqid___17391-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SETMAR protein levels (SeqId = 12462-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SETMAR protein levels (SeqId = 12462-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histone-lysine N-methyltransferase SETMAR	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000076	None	Gadd-DA_setmar_protein_levels__seqid___12462-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RNGTT protein levels (SeqId = 12847-27)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RNGTT protein levels (SeqId = 12847-27)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: mRNA-capping enzyme	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.208	0.000076	None	Gadd-DA_rngtt_protein_levels__seqid___12847-27__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	0.0326569	0.00825217	0.00007613563	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0507029	0.0128178	0.00007668008	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16737426	chr3:188139897	3	188139897	LPP	Open sea	-0.0326408	0.00825217	0.00007675859	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	0.032636	0.00825217	0.00007694496	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	NEGR1 protein levels (SeqId = 13109-82)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NEGR1 protein levels (SeqId = 13109-82)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Neuronal growth regulator 1	774	1	Adults (18-65 years)	Both	European	cg11555752	chr3:187925787	3	187925787	LPP	Open sea	0.7	0.178	0.000077	None	Gadd-DA_negr1_protein_levels__seqid___13109-82__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARF1 protein levels (SeqId = 19239-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARF1 protein levels (SeqId = 19239-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: ADP-ribosylation factor 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000077	None	Gadd-DA_arf1_protein_levels__seqid___19239-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CCL27 protein levels (SeqId = 2192-63)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CCL27 protein levels (SeqId = 2192-63)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-C motif chemokine 27	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000077	None	Gadd-DA_ccl27_protein_levels__seqid___2192-63__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LGALS7 protein levels (SeqId = 9196-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LGALS7 protein levels (SeqId = 9196-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Galectin-7	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.828	0.209	0.000077	None	Gadd-DA_lgals7_protein_levels__seqid___9196-8__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CYTH4 protein levels (SeqId = 12746-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CYTH4 protein levels (SeqId = 12746-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytohesin-4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000077	None	Gadd-DA_cyth4_protein_levels__seqid___12746-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.0392352	0.00992375	0.00007732409	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg08438870	chr3:187996496	3	187996496	LPP	Open sea	0.134079	0.0339174	0.00007744756	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0423516	0.0107143	0.00007760435	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05984281	chr3:188413418	3	188413418	LPP	Open sea	0.0343839	0.00869876	0.00007762403	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12314978	chr3:188324556	3	188324556	LPP	Open sea	0.0326166	0.00825218	0.0000777071	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04496578	chr3:188149132	3	188149132	LPP	Open sea	-0.0326136	0.00825218	0.00007782452	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	0.00199	0.0005	0.000078	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Gadd DA	Generation Scotland	35945220	31/07/2022	ERH protein levels (SeqId = 11614-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ERH protein levels (SeqId = 11614-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Enhancer of rudimentary homolog	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000078	None	Gadd-DA_erh_protein_levels__seqid___11614-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAEP protein levels (SeqId = 8867-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAEP protein levels (SeqId = 8867-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glycodelin	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000078	None	Gadd-DA_paep_protein_levels__seqid___8867-18__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.047282	0.0119655	0.00007801357	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.193429	0.0489538	0.00007805185	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.032604	0.00825218	0.00007820565	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14464975	chr3:188223899	3	188223899	LPP	Open sea	0.0335686	0.00849756	0.00007839151	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.055055	0.0139377	0.0000784868	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.0343926	0.00870736	0.00007857056	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	-0.0325934	0.00825218	0.00007862328	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04430	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04430	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0325922	0.00825219	0.00007867114	P04430	41361833_Josephine_Robertson_P04430_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0325914	0.00825219	0.000078703	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03548412	chr3:188063126	3	188063126	LPP	Open sea	-0.0330452	0.00836716	0.00007871567	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg25080260	chr3:188088115	3	188088115	LPP	Open sea	0.152484	0.0386177	0.00007893845	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	-0.023	0.00575	0.000079	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	PPARA protein levels (SeqId = 12954-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PPARA protein levels (SeqId = 12954-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxisome proliferator-activated receptor alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000079	None	Gadd-DA_ppara_protein_levels__seqid___12954-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAN protein levels (SeqId = 4282-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAN protein levels (SeqId = 4282-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GTP-binding nuclear protein Ran	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000079	None	Gadd-DA_ran_protein_levels__seqid___4282-3__somascan_protein_measurement
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	metolachlor	None	discovery	10.5281/zenodo.5156585	DNA methylation	metolachlor	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	507	1	Adults	Males	European	cg25984398	chr3:188114354	3	188114354	LPP	Open sea	-0.00381	0.00097	0.000079	None	34516295_Hoang_metolachlor_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0471987	0.011955	0.00007915892	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	0.188836	0.0478411	0.00007938049	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09054339	chr3:188265293	3	188265293	LPP	Open sea	-0.0325736	0.00825219	0.00007941635	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0549907	0.0139338	0.00007964981	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00119073	chr3:187870713	3	187870713	LPP	North shore	0.0325673	0.00825219	0.00007967	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	XCL2 protein levels (SeqId = 15617-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	XCL2 protein levels (SeqId = 15617-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytokine SCM-1 beta	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.00008	None	Gadd-DA_xcl2_protein_levels__seqid___15617-8__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	0.0325511	0.0082522	0.00008032465	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	-0.0325474	0.0082522	0.0000804755	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	-0.0356453	0.00903795	0.00008052157	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0644614	0.01635	0.00008098386	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg18127680	chr3:187871034	3	187871034	LPP	North shore	None	None	0.000081	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	IL2RB protein levels (SeqId = 9343-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL2RB protein levels (SeqId = 9343-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-2 receptor subunit beta	774	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	0.76	0.193	0.000081	None	Gadd-DA_il2rb_protein_levels__seqid___9343-16__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAF2 protein levels (SeqId = 9738-7)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAF2 protein levels (SeqId = 9738-7)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: FAS-associated factor 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.208	0.000081	None	Gadd-DA_faf2_protein_levels__seqid___9738-7__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ASPH protein levels (SeqId = 6998-106)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASPH protein levels (SeqId = 6998-106)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aspartyl/asparaginyl beta-hydroxylase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000081	None	Gadd-DA_asph_protein_levels__seqid___6998-106__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CHP1 protein levels (SeqId = 12458-79)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CHP1 protein levels (SeqId = 12458-79)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calcineurin B homologous protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.208	0.000081	None	Gadd-DA_chp1_protein_levels__seqid___12458-79__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DEFB121 protein levels (SeqId = 5765-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DEFB121 protein levels (SeqId = 5765-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-defensin 121	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.83	0.209	0.000081	None	Gadd-DA_defb121_protein_levels__seqid___5765-53__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LST1 protein levels (SeqId = 9531-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LST1 protein levels (SeqId = 9531-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leukocyte-specific transcript 1 protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000081	None	Gadd-DA_lst1_protein_levels__seqid___9531-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GPC5 protein levels (SeqId = 4991-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GPC5 protein levels (SeqId = 4991-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glypican-5	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000081	None	Gadd-DA_gpc5_protein_levels__seqid___4991-12__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GGPS1 protein levels (SeqId = 17786-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GGPS1 protein levels (SeqId = 17786-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Geranylgeranyl pyrophosphate synthase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.825	0.209	0.000081	None	Gadd-DA_ggps1_protein_levels__seqid___17786-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ARPP19 protein levels (SeqId = 4963-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ARPP19 protein levels (SeqId = 4963-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: cAMP-regulated phosphoprotein 19	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000081	None	Gadd-DA_arpp19_protein_levels__seqid___4963-19__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03548412	chr3:188063126	3	188063126	LPP	Open sea	-0.0328	0.0083201	0.00008109106	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	0.0325315	0.0082522	0.00008112455	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	0.0325305	0.0082522	0.0000811661	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.0325301	0.0082522	0.00008118377	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0325196	0.0082522	0.00008161428	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14946988	chr3:188552390	3	188552390	LPP	Open sea	0.0325189	0.0082522	0.0000816435	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26318252	chr3:188281073	3	188281073	LPP	Open sea	-0.0335619	0.00851693	0.00008165288	P00748	41361833_Josephine_Robertson_P00748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	0.0325169	0.00825221	0.00008172669	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03883323	chr3:188404960	3	188404960	LPP	Open sea	-0.0334175	0.00848104	0.00008176924	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0381395	0.00968087	0.00008196721	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	NSFL1C protein levels (SeqId = 4250-23)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NSFL1C protein levels (SeqId = 4250-23)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NSFL1 cofactor p47	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.208	0.000082	None	Gadd-DA_nsfl1c_protein_levels__seqid___4250-23__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22999644	chr3:187920143	3	187920143	LPP	Open sea	-0.0325018	0.00825221	0.00008235309	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11344771	chr3:188108786	3	188108786	LPP	Open sea	0.0324989	0.00825221	0.00008247304	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10236666	chr3:188415034	3	188415034	LPP	Open sea	-0.0324957	0.00825221	0.00008260758	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01009	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01009	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14696728	chr3:188149653	3	188149653	LPP	Open sea	-0.0324955	0.00825221	0.00008261441	P01009	41361833_Josephine_Robertson_P01009_OSCA_model_1
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	malathion	CHEBI_6651	discovery	10.5281/zenodo.5156585	DNA methylation	malathion	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	232	1	Adults	Males	European	cg05707781	chr3:188464815	3	188464815	LPP	Open sea	-0.00918	0.0023	0.000083	None	34516295_Hoang_malathion_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	CSAG1 protein levels (SeqId = 5716-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CSAG1 protein levels (SeqId = 5716-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Putative chondrosarcoma-associated gene 1 protein	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.208	0.000083	None	Gadd-DA_csag1_protein_levels__seqid___5716-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NAGK protein levels (SeqId = 3894-15)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAGK protein levels (SeqId = 3894-15)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: N-acetyl-D-glucosamine kinase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000083	None	Gadd-DA_nagk_protein_levels__seqid___3894-15__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NIP7 protein levels (SeqId = 12564-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NIP7 protein levels (SeqId = 12564-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: 60S ribosome subunit biogenesis protein NIP7 homolog	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000083	None	Gadd-DA_nip7_protein_levels__seqid___12564-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.033019	0.0083879	0.00008305956	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.039593	0.0100593	0.00008324972	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.0550959	0.0139981	0.00008325357	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0422669	0.0107431	0.00008380731	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	CD79B protein levels (SeqId = 6351-55)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CD79B protein levels (SeqId = 6351-55)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: B-cell antigen receptor complex-associated protein beta chain	774	1	Adults (18-65 years)	Both	European	cg18896634	chr3:188191833	3	188191833	LPP	Open sea	-0.53	0.14	0.000084	None	Gadd-DA_cd79b_protein_levels__seqid___6351-55__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg04423294	chr3:188479059	3	188479059	LPP	Open sea	-1.098217	0.2793	0.0000841	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	0.0324584	0.00825222	0.00008417517	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01718	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01718	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22575300	chr3:188034516	3	188034516	LPP	Open sea	-0.0543188	0.0138103	0.00008420321	P01718	41361833_Josephine_Robertson_P01718_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	0.0324574	0.00825222	0.00008421822	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0341633	0.00868817	0.00008457034	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0699291	0.0177844	0.00008461459	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15958366	chr3:187957027	3	187957027	LPP	Open sea	-0.0324426	0.00825223	0.00008485024	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	-1.1	0.283	0.000085	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	ROBO1 protein levels (SeqId = 5740-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ROBO1 protein levels (SeqId = 5740-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Roundabout homolog 1	774	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	-0.867	0.221	0.000085	None	Gadd-DA_robo1_protein_levels__seqid___5740-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	STK17B protein levels (SeqId = 8399-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	STK17B protein levels (SeqId = 8399-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase 17B	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000085	None	Gadd-DA_stk17b_protein_levels__seqid___8399-6__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IMPDH2 protein levels (SeqId = 5250-53)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IMPDH2 protein levels (SeqId = 5250-53)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inosine-5'-monophosphate dehydrogenase 2	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000085	None	Gadd-DA_impdh2_protein_levels__seqid___5250-53__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.0324352	0.00825223	0.00008516408	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0466513	0.0118701	0.00008528805	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.0425254	0.0108225	0.0000855668	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.0324248	0.00825223	0.00008561519	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0509392	0.0129657	0.00008577647	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	RRAGC protein levels (SeqId = 12548-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RRAGC protein levels (SeqId = 12548-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related GTP-binding protein C	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.208	0.000086	None	Gadd-DA_rragc_protein_levels__seqid___12548-75__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0383583	0.00976579	0.00008610918	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0545862	0.0138988	0.00008625999	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.0324066	0.00825223	0.00008640192	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	0.132449	0.0337326	0.00008653313	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17585528	chr3:187988060	3	187988060	LPP	Open sea	0.0330097	0.00840785	0.00008674234	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03759769	chr3:188204895	3	188204895	LPP	Open sea	-0.0364494	0.00928492	0.00008688921	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21779805	chr3:187982495	3	187982495	LPP	Open sea	0.0012	None	0.000087	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	TCP1 protein levels (SeqId = 19265-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TCP1 protein levels (SeqId = 19265-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: T-complex protein 1 subunit alpha	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000087	None	Gadd-DA_tcp1_protein_levels__seqid___19265-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03550494	chr3:187904960	3	187904960	LPP	Open sea	0.0517994	0.0131972	0.00008711362	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15120525	chr3:188108233	3	188108233	LPP	Open sea	-0.0323847	0.00825224	0.00008736066	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.0323844	0.00825224	0.00008737534	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27106936	chr3:188038551	3	188038551	LPP	Open sea	-0.0323764	0.00825224	0.00008772721	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21036986	chr3:188464408	3	188464408	LPP	Open sea	0.0354635	0.00903916	0.00008773491	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	0.0323759	0.00825224	0.00008774677	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0323759	0.00825224	0.00008774838	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03548412	chr3:188063126	3	188063126	LPP	Open sea	-0.0327858	0.00835676	0.00008775349	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	-0.0469171	0.0119606	0.00008798508	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg26172051	chr3:187914247	3	187914247	LPP	Open sea	0.034	0.00868	0.000088	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	MAP2K1 protein levels (SeqId = 2864-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MAP2K1 protein levels (SeqId = 2864-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dual specificity mitogen-activated protein kinase kinase 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000088	None	Gadd-DA_map2k1_protein_levels__seqid___2864-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DEFB1 protein levels (SeqId = 6629-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DEFB1 protein levels (SeqId = 6629-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-defensin 1	774	1	Adults (18-65 years)	Both	European	cg09420838	chr3:187990766	3	187990766	LPP	Open sea	1.016	0.259	0.000088	None	Gadd-DA_defb1_protein_levels__seqid___6629-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	-0.0366222	0.00933808	0.00008828468	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03945529	chr3:188024721	3	188024721	LPP	Open sea	-0.0344284	0.00877977	0.00008846005	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02306900	chr3:188466920	3	188466920	LPP	Open sea	-0.0330085	0.00841797	0.00008851342	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0382865	0.0097661	0.00008882523	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00075331	chr3:188271393	3	188271393	LPP	Open sea	0.0323495	0.00825225	0.00008892264	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11018547	chr3:188599043	3	188599043	LPP	Open sea	-0.146205	0.0372989	0.00008895169	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFRSF12A protein levels (SeqId = 5138-50)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFRSF12A protein levels (SeqId = 5138-50)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor receptor superfamily member 12A	774	1	Adults (18-65 years)	Both	European	cg00869941	chr3:187929592	3	187929592	LPP	Open sea	0.72	0.184	0.000089	None	Gadd-DA_tnfrsf12a_protein_levels__seqid___5138-50__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SERPINC1 protein levels (SeqId = 3344-60)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SERPINC1 protein levels (SeqId = 3344-60)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Antithrombin-III	774	1	Adults (18-65 years)	Both	European	cg06813127	chr3:188014924	3	188014924	LPP	Open sea	-0.55	0.14	0.000089	None	Gadd-DA_serpinc1_protein_levels__seqid___3344-60__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SOS1 protein levels (SeqId = 9923-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SOS1 protein levels (SeqId = 9923-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Son of sevenless homolog 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.208	0.000089	None	Gadd-DA_sos1_protein_levels__seqid___9923-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18127680	chr3:187871034	3	187871034	LPP	North shore	-0.0323464	0.00825225	0.0000890598	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg01678383	chr3:187903164	3	187903164	LPP	Open sea	-0.117139	0.0298887	0.00008917975	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	-0.0323327	0.00825225	0.00008967445	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14076	1	Adults (18-65y)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.024	0.00622	0.00009	None	Robert-F-Hillary_Incident_COPD_Fully-adjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	TSSC4 protein levels (SeqId = 18181-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TSSC4 protein levels (SeqId = 18181-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein TSSC4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.00009	None	Gadd-DA_tssc4_protein_levels__seqid___18181-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ATOX1 protein levels (SeqId = 19233-75)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ATOX1 protein levels (SeqId = 19233-75)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Copper transport protein ATOX1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.00009	None	Gadd-DA_atox1_protein_levels__seqid___19233-75__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NXPH3 protein levels (SeqId = 6054-6)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NXPH3 protein levels (SeqId = 6054-6)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Neurexophilin-3	774	1	Adults (18-65 years)	Both	European	cg18896634	chr3:188191833	3	188191833	LPP	Open sea	-0.53	0.135	0.00009	None	Gadd-DA_nxph3_protein_levels__seqid___6054-6__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0323206	0.00825226	0.00009022244	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05195776	chr3:188498449	3	188498449	LPP	Open sea	0.0323058	0.00825226	0.00009089589	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	DECR2 protein levels (SeqId = 18343-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DECR2 protein levels (SeqId = 18343-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Peroxisomal 2,4-dienoyl-CoA reductase	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000091	None	Gadd-DA_decr2_protein_levels__seqid___18343-10__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04773529	chr3:188225542	3	188225542	LPP	Open sea	0.032298	0.00825226	0.00009124985	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	-0.043181	0.0110332	0.0000912893	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	-0.0064	0.0016	0.000092	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg25853622	chr3:188425256	3	188425256	LPP	Open sea	-2	0.506	0.000092	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Gadd DA	Generation Scotland	35945220	31/07/2022	FIGF protein levels (SeqId = 13098-93)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FIGF protein levels (SeqId = 13098-93)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vascular endothelial growth factor D	774	1	Adults (18-65 years)	Both	European	cg07199059	chr3:188243862	3	188243862	LPP	Open sea	0.695	0.178	0.000092	None	Gadd-DA_figf_protein_levels__seqid___13098-93__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ZNF34 protein levels (SeqId = 18265-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ZNF34 protein levels (SeqId = 18265-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Zinc finger protein 34	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000092	None	Gadd-DA_znf34_protein_levels__seqid___18265-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DNAJC17 protein levels (SeqId = 14655-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNAJC17 protein levels (SeqId = 14655-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DnaJ homolog subfamily C member 17	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000092	None	Gadd-DA_dnajc17_protein_levels__seqid___14655-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SYTL4 protein levels (SeqId = 9090-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SYTL4 protein levels (SeqId = 9090-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Synaptotagmin-like protein 4	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000092	None	Gadd-DA_sytl4_protein_levels__seqid___9090-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19599666	chr3:187871024	3	187871024	LPP	North shore	-0.0322812	0.00825227	0.0000920242	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	-0.0322744	0.00825227	0.00009234139	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P13671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P13671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03970811	chr3:187915328	3	187915328	LPP	Open sea	-0.0322738	0.00825227	0.0000923677	P13671	41361833_Josephine_Robertson_P13671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04568100	chr3:188471224	3	188471224	LPP	Open sea	-0.0322728	0.00825227	0.00009241159	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	0.054534	0.0139447	0.00009242787	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20893542	chr3:187929286	3	187929286	LPP	Open sea	-0.0293678	0.00751113	0.00009274681	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0340541	0.008711	0.0000929704	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02749	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02749	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06739107	chr3:188399479	3	188399479	LPP	Open sea	-0.0865517	0.0221399	0.0000929756	P02749	41361833_Josephine_Robertson_P02749_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	PCBP1 protein levels (SeqId = 11458-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PCBP1 protein levels (SeqId = 11458-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Poly(rC)-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000093	None	Gadd-DA_pcbp1_protein_levels__seqid___11458-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NRG1 protein levels (SeqId = 15446-25)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NRG1 protein levels (SeqId = 15446-25)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pro-neuregulin-1, membrane-bound isoform	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000093	None	Gadd-DA_nrg1_protein_levels__seqid___15446-25__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04387984	chr3:188291633	3	188291633	LPP	Open sea	-0.0322583	0.00825227	0.00009308816	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06277469	chr3:188571433	3	188571433	LPP	Open sea	-0.0322563	0.00825228	0.0000931815	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg25037104	chr3:188510700	3	188510700	LPP	Open sea	0.0335872	0.00859335	0.00009328552	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23060272	chr3:187870863	3	187870863	LPP	North shore	-0.0413946	0.0105918	0.00009341182	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23181899	chr3:188021823	3	188021823	LPP	Open sea	0.0322429	0.00825228	0.00009381051	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20866090	chr3:188537167	3	188537167	LPP	Open sea	0.0011	None	0.000094	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24123854	chr3:187973091	3	187973091	LPP	Open sea	-0.0031	0.00081	0.000094	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	B4GALT7 protein levels (SeqId = 7806-33)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	B4GALT7 protein levels (SeqId = 7806-33)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-1,4-galactosyltransferase 7	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000094	None	Gadd-DA_b4galt7_protein_levels__seqid___7806-33__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0322335	0.00825228	0.00009425154	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0439316	0.0112481	0.00009437796	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	-0.0322293	0.00825228	0.00009445313	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16224163	chr3:187870621	3	187870621	LPP	North shore	-0.0327923	0.00839734	0.00009461321	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01341486	chr3:188107889	3	188107889	LPP	Open sea	0.0322243	0.00825228	0.00009468822	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.05069	0.0129817	0.00009475254	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01009	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01009	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0322213	0.00825228	0.00009483072	P01009	41361833_Josephine_Robertson_P01009_OSCA_model_1
Cardenas A	Project Viva	31300640	Jul 12, 2019	fractional exhaled nitric oxide (FeNO)	EFO_0005536	None	Supplementary Data 2	DNA methylation	fractional exhaled nitric oxide (FeNO)	Age, Sex, Smoking, Cell composition (reference free), Batch effects, Ancestry (other), Body mass index, Education, sine and cosine of season at sample collection	Beta values	ppb	Illumina HumanMethylationEPIC	nasal epithelium	None	517	1	Children	Both	Other	cg14120161	chr3:188012097	3	188012097	LPP	Open sea	3.45	0.877	0.000095	SE manually calculated	31300640_Cardenas-A_fractional_exhaled_nitric_oxide__feno_
Gadd DA	Generation Scotland	35945220	31/07/2022	HINT1 protein levels (SeqId = 5900-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HINT1 protein levels (SeqId = 5900-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histidine triad nucleotide-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000095	None	Gadd-DA_hint1_protein_levels__seqid___5900-11__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0322137	0.00825229	0.00009519102	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01706	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01706	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27524103	chr3:187957576	3	187957576	LPP	Open sea	0.0322111	0.00825229	0.00009531764	P01706	41361833_Josephine_Robertson_P01706_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09787101	chr3:188573583	3	188573583	LPP	Open sea	0.0429386	0.0110012	0.00009540008	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07584150	chr3:187883547	3	187883547	LPP	Open sea	-0.0322016	0.00825229	0.00009577346	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	0.121546	0.0311506	0.00009578715	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.0321983	0.00825229	0.00009592882	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10387648	chr3:188382822	3	188382822	LPP	Open sea	0.0321981	0.00825229	0.00009593716	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	BMX protein levels (SeqId = 3414-40)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BMX protein levels (SeqId = 3414-40)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytoplasmic tyrosine-protein kinase BMX	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000096	None	Gadd-DA_bmx_protein_levels__seqid___3414-40__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GOT1 protein levels (SeqId = 4912-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GOT1 protein levels (SeqId = 4912-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aspartate aminotransferase, cytoplasmic	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000096	None	Gadd-DA_got1_protein_levels__seqid___4912-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLINT1 protein levels (SeqId = 11659-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLINT1 protein levels (SeqId = 11659-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Clathrin interactor 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.81	0.208	0.000096	None	Gadd-DA_clint1_protein_levels__seqid___11659-31__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ACBD7 protein levels (SeqId = 13563-259)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ACBD7 protein levels (SeqId = 13563-259)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Acyl-CoA-binding domain-containing protein 7	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.81	0.209	0.000096	None	Gadd-DA_acbd7_protein_levels__seqid___13563-259__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EPS15L1 protein levels (SeqId = 4212-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EPS15L1 protein levels (SeqId = 4212-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Epidermal growth factor receptor substrate 15-like 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.81	0.208	0.000096	None	Gadd-DA_eps15l1_protein_levels__seqid___4212-5__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg23651889	chr3:188115336	3	188115336	LPP	Open sea	0.0915459	0.0234789	0.00009690734	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg15959020	chr3:188494428	3	188494428	LPP	Open sea	0.02	0.00501	0.000097	None	Robert-F-Hillary_Incident_COPD_Basic_model
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	picloram	None	discovery	10.5281/zenodo.5156585	DNA methylation	picloram	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	1011	1	Adults	Males	European	cg12529561	chr3:188535876	3	188535876	LPP	Open sea	-0.04848	0.012	0.000097	None	34516295_Hoang_picloram_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09930672	chr3:188151744	3	188151744	LPP	Open sea	-0.0321732	0.0082523	0.00009714196	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14145614	chr3:187888471	3	187888471	LPP	Open sea	0.0462682	0.0118693	0.00009736029	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22984270	chr3:188003919	3	188003919	LPP	Open sea	-0.0321657	0.0082523	0.00009750657	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P15169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P15169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg02524983	chr3:188012918	3	188012918	LPP	Open sea	0.0466347	0.0119659	0.0000976977	P15169	41361833_Josephine_Robertson_P15169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07925274	chr3:188225454	3	188225454	LPP	Open sea	0.0415245	0.010656	0.00009789352	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	MRRF protein levels (SeqId = 12355-223)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MRRF protein levels (SeqId = 12355-223)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ribosome-recycling factor, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.81	0.209	0.000098	None	Gadd-DA_mrrf_protein_levels__seqid___12355-223__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DEFB110 protein levels (SeqId = 8340-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DEFB110 protein levels (SeqId = 8340-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-defensin 110	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000098	None	Gadd-DA_defb110_protein_levels__seqid___8340-9__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PEAR1 protein levels (SeqId = 8275-31)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PEAR1 protein levels (SeqId = 8275-31)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet endothelial aggregation receptor 1	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.82	0.209	0.000098	None	Gadd-DA_pear1_protein_levels__seqid___8275-31__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01762	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01762	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18853981	chr3:188302105	3	188302105	LPP	Open sea	-0.0321523	0.0082523	0.00009816363	P01762	41361833_Josephine_Robertson_P01762_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27184673	chr3:188539911	3	188539911	LPP	Open sea	-0.055138	0.014152	0.00009817185	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg20756287	chr3:188296515	3	188296515	LPP	Open sea	-0.0321484	0.0082523	0.00009835356	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22005677	chr3:188374040	3	188374040	LPP	Open sea	-0.0395807	0.0101612	0.00009852488	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19018034	chr3:188057596	3	188057596	LPP	Open sea	0.0697882	0.0179196	0.0000988292	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	0.0383927	0.0098584	0.00009887331	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02904838	chr3:187871519	3	187871519	LPP	Island	-0.00527	0.00133	0.000099	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	malathion	CHEBI_6651	discovery	10.5281/zenodo.5156585	DNA methylation	malathion	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	232	1	Adults	Males	European	cg14306812	chr3:187871538	3	187871538	LPP	Island	-0.00048	0.00012	0.000099	None	34516295_Hoang_malathion_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	TMPO protein levels (SeqId = 8265-225)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TMPO protein levels (SeqId = 8265-225)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Lamina-associated polypeptide 2, isoforms beta/gamma	774	1	Adults (18-65 years)	Both	European	cg00381298	chr3:187958283	3	187958283	LPP	Open sea	0.81	0.209	0.000099	None	Gadd-DA_tmpo_protein_levels__seqid___8265-225__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00902153	chr3:188506715	3	188506715	LPP	Open sea	0.0379236	0.00973978	0.00009917164	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg11323106	chr3:188490680	3	188490680	LPP	Open sea	0.0321311	0.00825231	0.00009921159	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06656157	chr3:188207606	3	188207606	LPP	Open sea	0.0500166	0.0128476	0.00009942051	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03396047	chr3:188118309	3	188118309	LPP	Open sea	0.0478213	0.0122858	0.00009970059	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04430	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04430	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01479491	chr3:188059305	3	188059305	LPP	Open sea	-0.0321192	0.00825231	0.00009980252	P04430	41361833_Josephine_Robertson_P04430_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27359557	chr3:188034956	3	188034956	LPP	Open sea	-0.0321166	0.00825231	0.00009992932	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1