author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00807871	chr6:37617124	6	37617124	MDGA1	Island	0.0047	0.00029	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00807871	chr6:37617124	6	37617124	MDGA1	Island	-0.011	0.0011	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00807871	chr6:37617124	6	37617124	MDGA1	Island	0.0083	None	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01025604	chr6:37614550	6	37614550	MDGA1	North shore	-0.00097	0.000097	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	0.0098	0.00041	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	-0.026	0.002	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03062252	chr6:37616598	6	37616598	MDGA1	Island	0.0016	0.00013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03062252	chr6:37616598	6	37616598	MDGA1	Island	0.0036	None	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03131171	chr6:37616686	6	37616686	MDGA1	North shore	0.0025	0.00013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	0.0021	0.00016	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	-0.011	0.0011	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	-0.024	0.0021	0	None	33450751_Mulder-RH_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.013	0.0013	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	0.0081	0.00036	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.022	0.0017	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	0.0099	0.00047	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-0.034	0.0021	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24442454	chr6:37616803	6	37616803	MDGA1	Island	0.0044	0.00016	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24442454	chr6:37616803	6	37616803	MDGA1	Island	-0.0069	0.00072	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24442454	chr6:37616803	6	37616803	MDGA1	Island	0.0044	None	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24456094	chr6:37626607	6	37626607	MDGA1	South shore	-0.005	0.00026	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	0.0094	0.00048	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	-0.042	0.0023	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	0.0066	0.00038	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	-0.028	0.0018	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27103616	chr6:37626335	6	37626335	MDGA1	Island	-0.0018	0.00012	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	0.011	None	3e-316	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	0.013	None	8.8e-247	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	0.0097	None	5.5e-204	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03131171	chr6:37616686	6	37616686	MDGA1	North shore	0.0024	None	4.6e-153	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	0.0086	None	3.2e-135	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04680754	chr6:37612545	6	37612545	MDGA1	North shelf	0.52144	0.00871	1.3e-126	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07693262	chr6:37625029	6	37625029	MDGA1	North shore	0.44796	0.00837	9.4e-118	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	0.01	None	1.1000000000000001e-110	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07260849	chr6:37621232	6	37621232	MDGA1	South shelf	0.34439	0.00797	3.7e-101	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg27103616	chr6:37626335	6	37626335	MDGA1	Island	0.14163	0.00337	5.4e-99	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	0.92	0.045	7e-93	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	0.56	0.028	1e-90	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	0.59	0.03	9.8e-88	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03062252	chr6:37616598	6	37616598	MDGA1	Island	0.0074	None	1.6e-84	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg18821972	chr6:37660403	6	37660403	MDGA1	North shelf	1.58	0.083	1.6000000000000002e-81	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	0.8	0.042	1.3e-79	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	1.01	0.054	2e-78	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg24214440	chr6:37661621	6	37661621	MDGA1	North shelf	1.6	0.087	1.2e-76	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00807871	chr6:37617124	6	37617124	MDGA1	Island	0.017	None	5.799999999999999e-75	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15580968	chr6:37619709	6	37619709	MDGA1	South shore	-0.07599	0.00286	1.8e-66	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	-0.28089	0.01129	4.1e-62	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.133756	0.00818238	1.5400000000000001e-59	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	1.23	0.078	8.3e-56	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-0.32025	0.01513	3.5e-52	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg07693262	chr6:37625029	6	37625029	MDGA1	North shore	2.4	0.16	6.2e-51	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	-0.2418	0.01188	6.6e-50	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg03062252	chr6:37616598	6	37616598	MDGA1	Island	0.9	0.061	1.9e-49	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.13825	0.00688	3.5e-49	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	-0.30664	0.01675	4.7e-44	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01025604	chr6:37614550	6	37614550	MDGA1	North shore	-0.0414	0.00227	5.999999999999999e-44	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12611575	chr6:37632065	6	37632065	MDGA1	Open sea	-0.04519	0.00249	1.6e-43	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg11001108	chr6:37618514	6	37618514	MDGA1	South shore	-0.04133	0.00228	1.8e-43	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	-3.66897	0.13839	1.9e-43	-	25282492_fetal_vs_adult_liver
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24442454	chr6:37616803	6	37616803	MDGA1	Island	0.0072	None	1.8e-42	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg27151561	chr6:37667101	6	37667101	MDGA1	Island	0.07899	0.00446	2.6e-42	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.112151	0.00820448	2.8051309999999998e-42	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	2.76	0.203	3.9999999999999995e-42	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg07693262	chr6:37625029	6	37625029	MDGA1	North shore	-	-	8.63e-39	-	23526956_clear_cell_renal_carcinoma
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26129310	chr6:37664451	6	37664451	MDGA1	Island	0.01647	0.00101	2.6e-38	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.102608	0.00821299	1.232493e-35	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg12257343	chr6:37608764	6	37608764	MDGA1	Open sea	2.34	0.188	1.4e-35	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg15580968	chr6:37619709	6	37619709	MDGA1	South shore	2.66	0.215	2.3999999999999999e-35	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21825443	chr6:37606394	6	37606394	MDGA1	Open sea	0.2211	0.01524	9.999999999999999e-33	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01025604	chr6:37614550	6	37614550	MDGA1	North shore	0.00097	None	6.100000000000001e-32	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	2.33	0.199	7.3e-32	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg27103616	chr6:37626335	6	37626335	MDGA1	Island	1.84	0.161	2.6000000000000002e-30	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg11001108	chr6:37618514	6	37618514	MDGA1	South shore	2.23	0.197	7.999999999999999e-30	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg03117073	chr6:37667057	6	37667057	MDGA1	Island	-1.69	0.156	2.5e-27	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	-0.03483	0.00279	1.3e-26	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2952323 (gene symbol: MDGA1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2952323 (gene symbol: MDGA1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg07260849	chr6:37621232	6	37621232	MDGA1	South shelf	None	None	1.4e-25	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2952323__gene_symbol__mdga1__meta-analysis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg00807871	chr6:37617124	6	37617124	MDGA1	Island	-0.2037	0.01679	1.5e-25	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0858015	0.00822612	2.210628e-25	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg26129310	chr6:37664451	6	37664451	MDGA1	Island	-1.51	0.145	3.6e-25	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg01576078	chr6:37615052	6	37615052	MDGA1	North shore	1.73	0.169	1.4999999999999998e-24	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg12702304	chr6:37626035	6	37626035	MDGA1	Island	0.02224	0.00192	7.499999999999999e-24	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	-1.87647	0.13604	1.3e-23	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0807308	0.00822962	1.199727e-22	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	-2.10977	0.15899	1.29e-22	-	25282492_fetal_vs_adult_liver
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg14058863	chr6:37615368	6	37615368	MDGA1	North shore	1.7	0.177	5.4e-22	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	-	-	5.95e-22	-	23526956_clear_cell_renal_carcinoma
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg25337070	chr6:37613874	6	37613874	MDGA1	North shelf	1.96	0.206	2.8e-21	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0776762	0.00823163	4.43074e-21	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0759156	0.00823275	3.331727e-20	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08494905	chr6:37663982	6	37663982	MDGA1	Island	0.01279	0.00125	6.6e-20	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0743976	0.00823369	1.8288839999999998e-19	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg21825443	chr6:37606394	6	37606394	MDGA1	Open sea	2.31	0.257	2.5e-19	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0737476	0.00823409	3.752773e-19	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0737454	0.00823409	3.7618049999999996e-19	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-1.68683	0.15174	2.21e-18	-	25282492_fetal_vs_adult_liver
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg14473485	chr6:37605107	6	37605107	MDGA1	Open sea	1.84	0.211	2.5e-18	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg21496942	chr6:37631813	6	37631813	MDGA1	Open sea	1.45	0.168	6.2e-18	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg01025604	chr6:37614550	6	37614550	MDGA1	North shore	1.08	0.125	7.9e-18	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27103616	chr6:37626335	6	37626335	MDGA1	Island	0.001	None	4.5e-17	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0678285	0.00823756	1.961379e-16	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15580968	chr6:37619709	6	37619709	MDGA1	South shore	-0.01	0.0012	2.2e-16	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg07260849	chr6:37621232	6	37621232	MDGA1	South shelf	1.06	0.13	3.3e-16	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0672672	0.00823787	3.457062e-16	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-1.47522	0.14807	4.81e-16	-	25282492_fetal_vs_adult_liver
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	1.87	0.231	7.1e-16	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14058863	chr6:37615368	6	37615368	MDGA1	North shore	-0.03293	0.00375	8.3e-16	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0924415	0.0115988	0.000000000000001704025	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg07889329	chr6:37666155	6	37666155	MDGA1	Island	0.01137	0.0014	0.00000000000000306	-	23334450_rheumatoid_arthritis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2952323 (gene symbol: MDGA1)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2952323 (gene symbol: MDGA1)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg27151561	chr6:37667101	6	37667101	MDGA1	Island	None	None	0.0000000000000036	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2952323__gene_symbol__mdga1__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0903927	0.0115875	0.000000000000006559809	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg02743437	chr6:37606804	6	37606804	MDGA1	Open sea	0.34	0.043	0.000000000000007	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0638025	0.00823975	0.00000000000001032135	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0627993	0.00824027	0.00000000000002670521	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24442454	chr6:37616803	6	37616803	MDGA1	Island	-0.08255	0.01021	0.000000000000066	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18821972	chr6:37660403	6	37660403	MDGA1	North shelf	-0.0082	0.0011	0.000000000000094	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12702304	chr6:37626035	6	37626035	MDGA1	Island	0.0013	None	0.00000000000025	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01025604	chr6:37614550	6	37614550	MDGA1	North shore	0.003	None	0.00000000000051	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.0595093	0.00824194	0.000000000000544225	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0588503	0.00824226	0.000000000000976701	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07345532	chr6:37631284	6	37631284	MDGA1	Open sea	-0.0176	0.00232	0.0000000000015	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08494905	chr6:37663982	6	37663982	MDGA1	Island	0.00035	0.000049	0.0000000000015	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0577767	0.00824278	0.000000000002498466	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24456094	chr6:37626607	6	37626607	MDGA1	South shore	-0.02926	0.00401	0.0000000000079	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0562932	0.00824348	0.000000000008898716	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age*sex	PATO_0000047,EFO_0000246	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	age*sex	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	0.0012	0.00018	0.000000000014	None	33450751_Mulder-RH_age_sex_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11753363	chr6:37626255	6	37626255	MDGA1	Island	0.0017	None	0.000000000021	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05792982	chr6:37622130	6	37622130	MDGA1	North shelf	0.00079	None	0.000000000028	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00962014	chr6:37666646	6	37666646	MDGA1	Island	0.00049	0.000073	0.000000000041	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg09185650	chr6:37664538	6	37664538	MDGA1	Island	0.01055	0.00153	0.000000000073	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0537117	0.00824465	0.00000000007519543	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0533207	0.00824483	0.0000000001030155	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg27151561	chr6:37667101	6	37667101	MDGA1	Island	0.95	0.149	0.00000000015	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg07345532	chr6:37631284	6	37631284	MDGA1	Open sea	-0.06722	0.0106	0.000000000189	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.052074	0.00824537	0.0000000002769775	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	0.0513494	0.00824568	0.0000000004870778	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.0513474	0.00824568	0.0000000004878391	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0508149	0.0082459	0.0000000007350598	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.0505809	0.008246	0.0000000008790002	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0588969	0.00974047	0.000000001515144	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.049809	0.00824632	0.000000001576984	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09185650	chr6:37664538	6	37664538	MDGA1	Island	0.167767	0.0278643	0.000000001768211	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14473485	chr6:37605107	6	37605107	MDGA1	Open sea	-0.00079	0.00013	0.0000000018	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.0495825	0.00824642	0.000000001868941	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg09185650	chr6:37664538	6	37664538	MDGA1	Island	-0.95	0.158	0.000000002	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg04680754	chr6:37612545	6	37612545	MDGA1	North shelf	-0.01916	0.0032	0.00000000219	-	23334450_rheumatoid_arthritis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18821972	chr6:37660403	6	37660403	MDGA1	North shelf	-0.00098	0.00017	0.0000000035	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15580968	chr6:37619709	6	37619709	MDGA1	South shore	0.0011	0.00018	0.0000000039	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0482972	0.00824694	0.000000004831876	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0479765	0.00824706	0.000000006101259	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0478476	0.00824711	0.000000006698263	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg27151561	chr6:37667101	6	37667101	MDGA1	Island	-0.156984	0.0271012	0.000000007048791	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0477443	0.00824716	0.000000007217632	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01278975	chr6:37662649	6	37662649	MDGA1	North shore	0.0019	None	0.0000000088	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0666928	0.0115897	0.000000008865041	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14058863	chr6:37615368	6	37615368	MDGA1	North shore	-0.0069	0.0012	0.0000000096	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07693262	chr6:37625029	6	37625029	MDGA1	North shore	-0.00093	0.00016	0.000000012	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0464599	0.00824766	0.00000001802495	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.046377	0.00824769	0.00000001910609	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0463758	0.00824769	0.00000001912193	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0805532	0.0143402	0.00000001974771	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0462019	0.00824775	0.00000002160029	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0461791	0.00824776	0.00000002194813	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg04680754	chr6:37612545	6	37612545	MDGA1	North shelf	-0.08533	0.0153	0.0000000229	-	25650246_gestational_age
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg00962014	chr6:37666646	6	37666646	MDGA1	Island	0.0026	0.00047	0.000000023	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	0.0457468	0.00824793	0.00000002965416	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg11001108	chr6:37618514	6	37618514	MDGA1	South shore	-0.222812	0.0404462	0.00000003660942	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21825443	chr6:37606394	6	37606394	MDGA1	Open sea	-0.00083	0.00015	0.000000053	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.031	0.0052	0.000000055	None	32795589_Kyung-WK_atopy_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg12702304	chr6:37626035	6	37626035	MDGA1	Island	0.0039	None	0.000000059	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15105785	chr6:37665692	6	37665692	MDGA1	Island	0.0029	0.00054	0.000000072	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0443617	0.00824844	0.0000000763931	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	-0.044327	0.00824846	0.00000007819437	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05792982	chr6:37622130	6	37622130	MDGA1	North shelf	-0.191478	0.0357294	0.00000008464862	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11753363	chr6:37626255	6	37626255	MDGA1	Island	0.005	None	0.000000087	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.0439893	0.00824858	0.00000009805981	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0439189	0.0082486	0.0000001027794	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	-0.1178878	0.0221849	0.0000001073	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg12257343	chr6:37608764	6	37608764	MDGA1	Open sea	-0.204259	0.038489	0.0000001127775	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27151561	chr6:37667101	6	37667101	MDGA1	Island	-0.0437621	0.00824866	0.0000001140894	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg08455031	chr6:37620105	6	37620105	MDGA1	South shore	0.96	0.182	0.00000012	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08494905	chr6:37663982	6	37663982	MDGA1	Island	0.0011	None	0.00000014	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg10019720	chr6:37628686	6	37628686	MDGA1	South shelf	-0.04002	0.0076	0.000000148	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0433507	0.00824881	0.0000001497832	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	-0.0432504	0.00824885	0.0000001600011	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0604438	0.0115913	0.0000001867422	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0428698	0.00824898	0.0000002052629	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0588859	0.0113317	0.0000002057493	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08455031	chr6:37620105	6	37620105	MDGA1	South shore	-0.00059	0.00011	0.00000021	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0423583	0.00824916	0.0000002859668	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	0.0459003	0.00896553	0.0000003099949	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0604024	0.0118586	0.0000003557585	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0494379	0.00970708	0.0000003568574	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0590571	0.0116072	0.0000003663568	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg11753363	chr6:37626255	6	37626255	MDGA1	Island	1.17	0.231	0.0000004	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.07223	0.01377	0.0000004	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15580968	chr6:37619709	6	37619709	MDGA1	South shore	0.043515	0.00861064	0.0000004387015	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27151561	chr6:37667101	6	37667101	MDGA1	Island	-0.0418706	0.0082934	0.0000004502295	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14473485	chr6:37605107	6	37605107	MDGA1	Open sea	0.0415315	0.00824945	0.0000004848751	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0581853	0.0115905	0.0000005225511	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0579776	0.0115957	0.0000005801478	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0595726	0.0119583	0.0000006374494	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.00094	0.00019	0.00000064	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0410186	0.00824962	0.0000006695317	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21825443	chr6:37606394	6	37606394	MDGA1	Open sea	0.0409413	0.00824965	0.0000007026475	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.040777	0.0082497	0.0000007784094	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0584063	0.0118393	0.0000008174947	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	0.0061	0.0012	0.00000084	None	33564054_Kashima-K_gestational_age
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24382801	chr6:37665291	6	37665291	MDGA1	Island	0.00033	0.000067	0.00000088	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg00170217	chr6:37643865	6	37643865	MDGA1	Open sea	0.9	0.184	0.00000098	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KPNA2 protein levels (SeqId = 2860-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KPNA2 protein levels (SeqId = 2860-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Importin subunit alpha-1	774	1	Adults (18-65 years)	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-0.135	0.028	0.000001	None	Gadd-DA_kpna2_protein_levels__seqid___2860-19__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg24456094	chr6:37626607	6	37626607	MDGA1	South shore	-0.131402	0.0269	0.00000102	-	27105112_hiv_infection_neutrophils
Gadd DA	Generation Scotland	35945220	31/07/2022	KPNA2 protein levels (SeqId = 2860-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KPNA2 protein levels (SeqId = 2860-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Importin subunit alpha-1	774	1	Adults (18-65 years)	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	-0.146	0.03	0.0000011	None	Gadd-DA_kpna2_protein_levels__seqid___2860-19__somascan_protein_measurement
Hoang	Agricultural Lung Health Study	34516295	Sep 13, 2021	2,4-Dichlorophenoxyacetic acid (2,4-D)	CHEBI_28854	discovery	10.5281/zenodo.5156585	DNA methylation	2,4-Dichlorophenoxyacetic acid (2,4-D)	Age, Smoking, Cell composition (reference based), residence,asthma	Beta values	None	Illumina HumanMethylationEPIC	whole blood	None	466	1	Adults	Males	European	cg00170217	chr6:37643865	6	37643865	MDGA1	Open sea	-0.00669	0.0014	0.0000011	None	34516295_Hoang_2_4-dichlorophenoxyacetic_acid__2_4-d__discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15580968	chr6:37619709	6	37619709	MDGA1	South shore	0.0415749	0.00855422	0.000001185032	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0400655	0.00824994	0.000001207351	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08494905	chr6:37663982	6	37663982	MDGA1	Island	0.0003	None	0.0000013	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0565623	0.011732	0.000001441174	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15105785	chr6:37665692	6	37665692	MDGA1	Island	0.136432	0.0283613	0.000001517595	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0396246	0.00825009	0.000001579066	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg19138755	chr6:37664611	6	37664611	MDGA1	Island	-0.86	0.178	0.0000016	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg21825443	chr6:37606394	6	37606394	MDGA1	Open sea	-0.242333	0.0508135	0.000001865074	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	0.0392469	0.00825021	0.000001982852	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	0.0076	0.0015	0.000002	None	33564054_Kashima-K_gestational_age
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg11001108	chr6:37618514	6	37618514	MDGA1	South shore	0.197975	0.0416407	0.000002006721	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0548438	0.0115996	0.000002287868	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	0.0424067	0.00898127	0.00000236065	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	-0.0389512	0.00825031	0.000002366397	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.0389222	0.00825032	0.000002407683	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0388008	0.00825035	0.000002587942	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15580968	chr6:37619709	6	37619709	MDGA1	South shore	0.0387407	0.00825037	0.000002681948	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg03131171	chr6:37616686	6	37616686	MDGA1	North shore	-0.02188	0.00452	0.0000027	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg15580968	chr6:37619709	6	37619709	MDGA1	South shore	-0.1455815	0.0310507	0.000002752	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08112479	chr6:37665626	6	37665626	MDGA1	Island	0.00015	0.000032	0.0000028	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09185650	chr6:37664538	6	37664538	MDGA1	Island	0.0022	0.00047	0.0000029	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	C4BPA protein levels (SeqId = 9449-150)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C4BPA protein levels (SeqId = 9449-150)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C4b-binding protein alpha chain	774	1	Adults (18-65 years)	Both	European	cg24214440	chr6:37661621	6	37661621	MDGA1	North shelf	-0.406	0.087	0.0000029	None	Gadd-DA_c4bpa_protein_levels__seqid___9449-150__somascan_protein_measurement
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg18821972	chr6:37660403	6	37660403	MDGA1	North shelf	-0.0909312	0.0194818	0.000003049	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg27151561	chr6:37667101	6	37667101	MDGA1	Island	-	-	0.00000308	-	26500701_sex_kora_f4
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15105785	chr6:37665692	6	37665692	MDGA1	Island	-0.00626	0.0013	0.0000031	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0563124	0.0120729	0.000003123232	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_2
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	-	-	0.00000322	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.054102	0.0116177	0.000003239104	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07260849	chr6:37621232	6	37621232	MDGA1	South shelf	0.0382287	0.00825054	0.0000036266	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	-0.0451194	0.00975765	0.000003796214	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	HGFAC protein levels (SeqId = 3617-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HGFAC protein levels (SeqId = 3617-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatocyte growth factor activator	774	1	Adults (18-65 years)	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	-0.14	0.03	0.0000039	None	Gadd-DA_hgfac_protein_levels__seqid___3617-80__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24382801	chr6:37665291	6	37665291	MDGA1	Island	0.002	0.00044	0.000004	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0555838	0.0120731	0.000004180851	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CKB protein levels (SeqId = 3714-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CKB protein levels (SeqId = 3714-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Creatine kinase B-type|Creatine kinase M-type	774	1	Adults (18-65 years)	Both	European	cg03117073	chr6:37667057	6	37667057	MDGA1	Island	0.72	0.157	0.0000044	None	Gadd-DA_ckb_protein_levels__seqid___3714-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPINK7 protein levels (SeqId = 10974-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPINK7 protein levels (SeqId = 10974-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine protease inhibitor Kazal-type 7	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.19	0.042	0.0000045	None	Gadd-DA_spink7_protein_levels__seqid___10974-20__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27103616	chr6:37626335	6	37626335	MDGA1	Island	0.003	None	0.0000047	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg01025604	chr6:37614550	6	37614550	MDGA1	North shore	0.0377658	0.00825068	0.000004749004	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	KPNA2 protein levels (SeqId = 2860-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KPNA2 protein levels (SeqId = 2860-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Importin subunit alpha-1	774	1	Adults (18-65 years)	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	-0.205	0.045	0.0000049	None	Gadd-DA_kpna2_protein_levels__seqid___2860-19__somascan_protein_measurement
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	0.0075	0.0016	0.000005	None	33564054_Kashima-K_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0529266	0.0116281	0.000005366582	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg24214440	chr6:37661621	6	37661621	MDGA1	North shelf	-0.2571789	0.0567066	0.000005753	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Gadd DA	Generation Scotland	35945220	31/07/2022	HGFAC protein levels (SeqId = 3617-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HGFAC protein levels (SeqId = 3617-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatocyte growth factor activator	774	1	Adults (18-65 years)	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-0.12	0.028	0.0000061	None	Gadd-DA_hgfac_protein_levels__seqid___3617-80__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPINK7 protein levels (SeqId = 10974-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPINK7 protein levels (SeqId = 10974-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine protease inhibitor Kazal-type 7	774	1	Adults (18-65 years)	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	-0.13	0.03	0.0000063	None	Gadd-DA_spink7_protein_levels__seqid___10974-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	HGFAC protein levels (SeqId = 3617-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HGFAC protein levels (SeqId = 3617-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatocyte growth factor activator	774	1	Adults (18-65 years)	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	-0.2	0.045	0.0000066	None	Gadd-DA_hgfac_protein_levels__seqid___3617-80__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01701	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01701	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	-0.0371375	0.00825088	0.00000681427	P01701	41361833_Josephine_Robertson_P01701_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26129310	chr6:37664451	6	37664451	MDGA1	Island	0.00055	None	0.000007	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	MDGA1 protein levels (SeqId = 16900-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MDGA1 protein levels (SeqId = 16900-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1	774	1	Adults (18-65 years)	Both	European	cg21045502	chr6:37620936	6	37620936	MDGA1	South shelf	0.54	0.121	0.0000071	None	Gadd-DA_mdga1_protein_levels__seqid___16900-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0369001	0.00825095	0.000007798947	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0498006	0.0111689	0.000008301373	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0367097	0.00825101	0.000008685795	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	-0.0367085	0.00825101	0.000008691877	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Sharp GC	-	25855720	2015-08-01	Maternal underweight	EFO_0005936	Birth	Additional file 1	DNA methylation	Maternal underweight	Offspring sex, maternal age, maternal smoking, maternal occupation, parity and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	601	1	0	Both	European	cg24442454	chr6:37616803	6	37616803	MDGA1	Island	0.01929	0.00434	0.00000885	-	25855720_maternal_underweight_birth
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0365909	0.00825104	0.000009287038	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03356760	chr6:37665051	6	37665051	MDGA1	Island	0.0365624	0.00825105	0.000009436981	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	HGFAC protein levels (SeqId = 3617-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HGFAC protein levels (SeqId = 3617-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatocyte growth factor activator	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.19	0.042	0.0000095	None	Gadd-DA_hgfac_protein_levels__seqid___3617-80__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	0.0382252	0.00863288	0.000009586152	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	0.0034	0.00074	0.00001	None	33564054_Kashima-K_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	-0.0363243	0.00825112	0.00001078423	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03356760	chr6:37665051	6	37665051	MDGA1	Island	0.00018	0.00004	0.000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0013	None	0.000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	-1.5	0.348	0.000011	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.219695	0.0499852	0.00001113314	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0522293	0.0119226	0.00001191187	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg08112479	chr6:37665626	6	37665626	MDGA1	Island	1.173107	0.2694	0.0000133	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0505368	0.0116009	0.00001331863	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.0358592	0.00825126	0.00001396388	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08494905	chr6:37663982	6	37663982	MDGA1	Island	0.0014	0.00032	0.000014	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.238899	0.0550588	0.00001439638	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.051495	0.0118716	0.000014496	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0355566	0.00825135	0.00001649209	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	-0.0355053	0.00825137	0.00001696229	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	SPINK7 protein levels (SeqId = 10974-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPINK7 protein levels (SeqId = 10974-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine protease inhibitor Kazal-type 7	774	1	Adults (18-65 years)	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-0.12	0.027	0.000017	None	Gadd-DA_spink7_protein_levels__seqid___10974-20__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRID2 protein levels (SeqId = 12758-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRID2 protein levels (SeqId = 12758-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutamate receptor ionotropic, delta-2	774	1	Adults (18-65 years)	Both	European	cg26129310	chr6:37664451	6	37664451	MDGA1	Island	0.629	0.146	0.000017	None	Gadd-DA_grid2_protein_levels__seqid___12758-47__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0354145	0.00825139	0.00001782485	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg07345532	chr6:37631284	6	37631284	MDGA1	Open sea	0.0013	0.00029	0.000018	None	33564054_Kashima-K_gestational_age
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	-0.177723	0.041447	0.00001813027	None	39706196_Hannah-M.-Smith_bmi_discovery
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg08494905	chr6:37663982	6	37663982	MDGA1	Island	-0.1209803	0.028245	0.00001842	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Gadd DA	Generation Scotland	35945220	31/07/2022	SPINK7 protein levels (SeqId = 10974-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPINK7 protein levels (SeqId = 10974-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine protease inhibitor Kazal-type 7	774	1	Adults (18-65 years)	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	-0.19	0.044	0.000019	None	Gadd-DA_spink7_protein_levels__seqid___10974-20__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07260849	chr6:37621232	6	37621232	MDGA1	South shelf	0.0373219	0.00878642	0.00002173241	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0349574	0.00825153	0.00002284439	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10019720	chr6:37628686	6	37628686	MDGA1	South shelf	0.02047	0.00472	0.000023	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0348202	0.00825156	0.00002459577	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.00019646	4.67e-05	0.0000283	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	CXCL17 protein levels (SeqId = 9495-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXCL17 protein levels (SeqId = 9495-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-X-C motif chemokine 17	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.18	0.042	0.000029	None	Gadd-DA_cxcl17_protein_levels__seqid___9495-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CKAP4 protein levels (SeqId = 7221-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CKAP4 protein levels (SeqId = 7221-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cytoskeleton-associated protein 4	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.18	0.042	0.000029	None	Gadd-DA_ckap4_protein_levels__seqid___7221-56__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.0344834	0.00825166	0.00002945328	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg21825443	chr6:37606394	6	37606394	MDGA1	Open sea	-0.098757	0.0236488	0.00002967	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Gadd DA	Generation Scotland	35945220	31/07/2022	PTGES3 protein levels (SeqId = 17154-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PTGES3 protein levels (SeqId = 17154-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Prostaglandin E synthase 3	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.175	0.042	0.000032	None	Gadd-DA_ptges3_protein_levels__seqid___17154-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.0482929	0.0116119	0.0000321568	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14473485	chr6:37605107	6	37605107	MDGA1	Open sea	0.00079	None	0.000033	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	ASPA protein levels (SeqId = 18187-16)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASPA protein levels (SeqId = 18187-16)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Aspartoacylase	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.17	0.042	0.000033	None	Gadd-DA_aspa_protein_levels__seqid___18187-16__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0473569	0.0114106	0.00003339548	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	DPEP2 protein levels (SeqId = 8327-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPEP2 protein levels (SeqId = 8327-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dipeptidase 2	774	1	Adults (18-65 years)	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	-0.12	0.03	0.000034	None	Gadd-DA_dpep2_protein_levels__seqid___8327-26__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	-0.0372636	0.00900635	0.00003531026	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	KPNA2 protein levels (SeqId = 2860-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KPNA2 protein levels (SeqId = 2860-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Importin subunit alpha-1	774	1	Adults (18-65 years)	Both	European	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	-0.222	0.054	0.000036	None	Gadd-DA_kpna2_protein_levels__seqid___2860-19__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04680754	chr6:37612545	6	37612545	MDGA1	North shelf	0.0032	0.00077	0.000036	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	0.0340018	0.0082518	0.00003800784	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.033956	0.00825181	0.00003893286	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03131171	chr6:37616686	6	37616686	MDGA1	North shore	-0.0034	0.00083	0.00004	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21045502	chr6:37620936	6	37620936	MDGA1	South shelf	-0.0072	0.0018	0.00004	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	0.033867	0.00825184	0.00004079549	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	KPNA2 protein levels (SeqId = 2860-19)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KPNA2 protein levels (SeqId = 2860-19)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Importin subunit alpha-1	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.174	0.042	0.000041	None	Gadd-DA_kpna2_protein_levels__seqid___2860-19__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MPO protein levels (SeqId = 2580-83)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MPO protein levels (SeqId = 2580-83)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Myeloperoxidase	774	1	Adults (18-65 years)	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-0.11	0.028	0.000041	None	Gadd-DA_mpo_protein_levels__seqid___2580-83__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	0.0357141	0.00871064	0.00004152831	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05248368	chr6:37632172	6	37632172	MDGA1	Open sea	-0.0338212	0.00825185	0.00004178445	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07889329	chr6:37666155	6	37666155	MDGA1	Island	-0.0337858	0.00825186	0.0000425657	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	EGLN1 protein levels (SeqId = 9901-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EGLN1 protein levels (SeqId = 9901-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Egl nine homolog 1	774	1	Adults (18-65 years)	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	-0.12	0.03	0.000043	None	Gadd-DA_egln1_protein_levels__seqid___9901-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EGLN1 protein levels (SeqId = 9901-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EGLN1 protein levels (SeqId = 9901-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Egl nine homolog 1	774	1	Adults (18-65 years)	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-0.11	0.028	0.000044	None	Gadd-DA_egln1_protein_levels__seqid___9901-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0336412	0.0082519	0.00004590434	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21045502	chr6:37620936	6	37620936	MDGA1	South shelf	-0.0011	0.00027	0.000046	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	23792949	2020-09-15	Ethnicity	EFO_0001799	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE39672. Compared European and African samples from HapMap (CEU and YRI)	None	DNA methylation	Ethnicity	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Lymphoblasts	None	133	1	Adults	Both	European, African	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	-0.271	0.0641	0.000049	None	23792949_Battram-T_ethnicity_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse39672__compared_european_and_african_samples_from_hapmap__ceu_and_yri_
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08455031	chr6:37620105	6	37620105	MDGA1	South shore	-0.00725	0.00175	0.000049	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg11001108	chr6:37618514	6	37618514	MDGA1	South shore	1.3	0.318	0.000049	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg24382801	chr6:37665291	6	37665291	MDGA1	Island	-0.241398	0.0596	0.0000513	-	27105112_hiv_infection_neutrophils
Gadd DA	Generation Scotland	35945220	31/07/2022	KRT17 protein levels (SeqId = 12923-51)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KRT17 protein levels (SeqId = 12923-51)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Keratin, type I cytoskeletal 17	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.17	0.042	0.000053	None	Gadd-DA_krt17_protein_levels__seqid___12923-51__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DPEP2 protein levels (SeqId = 8327-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPEP2 protein levels (SeqId = 8327-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dipeptidase 2	774	1	Adults (18-65 years)	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-0.11	0.028	0.000054	None	Gadd-DA_dpep2_protein_levels__seqid___8327-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRC37A2 protein levels (SeqId = 8897-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRC37A2 protein levels (SeqId = 8897-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leucine-rich repeat-containing protein 37A2	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.17	0.042	0.000057	None	Gadd-DA_lrrc37a2_protein_levels__seqid___8897-3__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PAPPA protein levels (SeqId = 4148-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PAPPA protein levels (SeqId = 4148-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pappalysin-1	774	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.94	0.232	0.000057	None	Gadd-DA_pappa_protein_levels__seqid___4148-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg18980073	chr6:37601581	6	37601581	MDGA1	Open sea	-0.0332187	0.00825201	0.00005713441	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14473485	chr6:37605107	6	37605107	MDGA1	Open sea	-0.0346689	0.00861946	0.00005795454	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05792982	chr6:37622130	6	37622130	MDGA1	North shelf	0.0023	None	0.000059	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03062252	chr6:37616598	6	37616598	MDGA1	Island	-0.0022	0.00055	0.00006	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	IGHM protein levels (SeqId = 3069-52)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IGHM protein levels (SeqId = 3069-52)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin heavy constant mu	774	1	Adults (18-65 years)	Both	European	cg26129310	chr6:37664451	6	37664451	MDGA1	Island	0.587	0.146	0.00006	None	Gadd-DA_ighm_protein_levels__seqid___3069-52__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg14058863	chr6:37615368	6	37615368	MDGA1	North shore	0.166613	0.0416	0.0000614	-	27105112_hiv_infection_neutrophils
Gadd DA	Generation Scotland	35945220	31/07/2022	CXCL17 protein levels (SeqId = 9495-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXCL17 protein levels (SeqId = 9495-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-X-C motif chemokine 17	774	1	Adults (18-65 years)	Both	European	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	-0.21	0.053	0.000062	None	Gadd-DA_cxcl17_protein_levels__seqid___9495-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	APBB1 protein levels (SeqId = 14206-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	APBB1 protein levels (SeqId = 14206-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Amyloid-beta A4 precursor protein-binding family B member 1	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.17	0.042	0.000063	None	Gadd-DA_apbb1_protein_levels__seqid___14206-28__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21825443	chr6:37606394	6	37606394	MDGA1	Open sea	0.00089	None	0.000063	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	GRID2 protein levels (SeqId = 12758-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRID2 protein levels (SeqId = 12758-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutamate receptor ionotropic, delta-2	774	1	Adults (18-65 years)	Both	European	cg04466022	chr6:37618123	6	37618123	MDGA1	Island	-0.312	0.078	0.000067	None	Gadd-DA_grid2_protein_levels__seqid___12758-47__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	RAB26 protein levels (SeqId = 6997-32)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RAB26 protein levels (SeqId = 6997-32)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ras-related protein Rab-26	774	1	Adults (18-65 years)	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-0.11	0.027	0.000067	None	Gadd-DA_rab26_protein_levels__seqid___6997-32__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLEC6A protein levels (SeqId = 6911-103)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLEC6A protein levels (SeqId = 6911-103)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-type lectin domain family 6 member A	774	1	Adults (18-65 years)	Both	European	cg24796644	chr6:37617956	6	37617956	MDGA1	Island	-0.12	0.03	0.000067	None	Gadd-DA_clec6a_protein_levels__seqid___6911-103__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg24382801	chr6:37665291	6	37665291	MDGA1	Island	0.0328812	0.00825211	0.00006792493	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.0478854	0.0120488	0.00007093391	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg27103616	chr6:37626335	6	37626335	MDGA1	Island	-0.0032	0.00081	0.000071	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	1.3	0.338	0.000071	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	SPINK7 protein levels (SeqId = 10974-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPINK7 protein levels (SeqId = 10974-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine protease inhibitor Kazal-type 7	774	1	Adults (18-65 years)	Both	European	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	-0.21	0.053	0.000072	None	Gadd-DA_spink7_protein_levels__seqid___10974-20__somascan_protein_measurement
Rebecca Richmond	SEE-Cigs	34583751	Sep 28, 2021	E-cigarette use	NCIT_C173621	e-cigarette use (vs. non-smoking)	Table 2	DNA methylation	E-cigarette use	Age, Sex, Body mass index, Education, household smoking, recreational drug use, 20 surrogate variables	Beta values	None	Illumina HumanMethylationEPIC	Saliva	None	228	1	Adults (18-65 years)	Both	Admixed	cg07260849	chr6:37621232	6	37621232	MDGA1	South shelf	-0.0351	0.00868	0.000072	None	34583751_Rebecca-Richmond_e-cigarette_use_e-cigarette_use__vs__non-smoking_
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg15105785	chr6:37665692	6	37665692	MDGA1	Island	0.00033	0.000082	0.000072	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	PLEKHA7 protein levels (SeqId = 12731-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLEKHA7 protein levels (SeqId = 12731-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pleckstrin homology domain-containing family A member 7	774	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.92	0.232	0.000074	None	Gadd-DA_plekha7_protein_levels__seqid___12731-12__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27216998	chr6:37665870	6	37665870	MDGA1	Island	0.0342185	0.00863856	0.00007494728	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	-0.0476363	0.0120345	0.00007583214	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	NBR1 protein levels (SeqId = 7696-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NBR1 protein levels (SeqId = 7696-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Next to BRCA1 gene 1 protein	774	1	Adults (18-65 years)	Both	European	cg24382801	chr6:37665291	6	37665291	MDGA1	Island	-0.71	0.179	0.000076	None	Gadd-DA_nbr1_protein_levels__seqid___7696-3__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg21045502	chr6:37620936	6	37620936	MDGA1	South shelf	0.01	0.0026	0.00008	None	33450751_Mulder-RH_sex_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	HGFAC protein levels (SeqId = 3617-80)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	HGFAC protein levels (SeqId = 3617-80)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Hepatocyte growth factor activator	774	1	Adults (18-65 years)	Both	European	cg02267270	chr6:37616410	6	37616410	MDGA1	Island	-0.21	0.054	0.000081	None	Gadd-DA_hgfac_protein_levels__seqid___3617-80__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CELA3B protein levels (SeqId = 6357-83)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CELA3B protein levels (SeqId = 6357-83)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chymotrypsin-like elastase family member 3B	774	1	Adults (18-65 years)	Both	European	cg14926196	chr6:37616482	6	37616482	MDGA1	Island	-0.17	0.042	0.000084	None	Gadd-DA_cela3b_protein_levels__seqid___6357-83__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg27151561	chr6:37667101	6	37667101	MDGA1	Island	-0.0311838	0.00792793	0.00008413361	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CAST protein levels (SeqId = 3026-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CAST protein levels (SeqId = 3026-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Calpastatin	774	1	Adults (18-65 years)	Both	European	cg26129310	chr6:37664451	6	37664451	MDGA1	Island	0.58	0.146	0.000085	None	Gadd-DA_cast_protein_levels__seqid___3026-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	GRID2 protein levels (SeqId = 12758-47)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GRID2 protein levels (SeqId = 12758-47)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutamate receptor ionotropic, delta-2	774	1	Adults (18-65 years)	Both	European	cg24214440	chr6:37661621	6	37661621	MDGA1	North shelf	-0.34	0.087	0.000085	None	Gadd-DA_grid2_protein_levels__seqid___12758-47__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07260849	chr6:37621232	6	37621232	MDGA1	South shelf	-0.0956856	0.0243479	0.00008530302	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22078284	chr6:37635331	6	37635331	MDGA1	Open sea	-0.0323742	0.00825224	0.00008782132	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg21277860	chr6:37609779	6	37609779	MDGA1	Open sea	-0.3239551	0.0826351	0.00008844	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01009	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01009	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08961187	chr6:37648275	6	37648275	MDGA1	Open sea	0.0323509	0.00825225	0.00008885945	P01009	41361833_Josephine_Robertson_P01009_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03356760	chr6:37665051	6	37665051	MDGA1	Island	0.0323302	0.00825226	0.00008978819	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	C4BPA protein levels (SeqId = 9449-150)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C4BPA protein levels (SeqId = 9449-150)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C4b-binding protein alpha chain	774	1	Adults (18-65 years)	Both	European	cg20053110	chr6:37617864	6	37617864	MDGA1	Island	-0.108	0.028	0.00009	None	Gadd-DA_c4bpa_protein_levels__seqid___9449-150__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	CLEC6A protein levels (SeqId = 6911-103)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CLEC6A protein levels (SeqId = 6911-103)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-type lectin domain family 6 member A	774	1	Adults (18-65 years)	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	-0.18	0.045	0.000091	None	Gadd-DA_clec6a_protein_levels__seqid___6911-103__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DPEP2 protein levels (SeqId = 8327-26)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPEP2 protein levels (SeqId = 8327-26)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dipeptidase 2	774	1	Adults (18-65 years)	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	-0.18	0.045	0.000093	None	Gadd-DA_dpep2_protein_levels__seqid___8327-26__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PROS1 protein levels (SeqId = 2700-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PROS1 protein levels (SeqId = 2700-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Vitamin K-dependent protein S	774	1	Adults (18-65 years)	Both	European	cg24214440	chr6:37661621	6	37661621	MDGA1	North shelf	-0.34	0.087	0.000093	None	Gadd-DA_pros1_protein_levels__seqid___2700-56__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MPO protein levels (SeqId = 2580-83)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MPO protein levels (SeqId = 2580-83)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Myeloperoxidase	774	1	Adults (18-65 years)	Both	European	cg24214440	chr6:37661621	6	37661621	MDGA1	North shelf	-0.34	0.087	0.000095	None	Gadd-DA_mpo_protein_levels__seqid___2580-83__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	C4BPA protein levels (SeqId = 9449-150)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	C4BPA protein levels (SeqId = 9449-150)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C4b-binding protein alpha chain	774	1	Adults (18-65 years)	Both	European	cg26720545	chr6:37618009	6	37618009	MDGA1	Island	-0.175	0.045	0.000097	None	Gadd-DA_c4bpa_protein_levels__seqid___9449-150__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15580968	chr6:37619709	6	37619709	MDGA1	South shore	-0.0321707	0.0082523	0.00009726447	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1