author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01603981	chr5:80043300	5	80043300	MSH3	Open sea	-0.0014	0.00017	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0013	0.00014	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18434588	chr5:80095132	5	80095132	MSH3	Open sea	-0.0014	0.00013	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24866363	chr5:80050837	5	80050837	MSH3	Open sea	0.0011	0.00012	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg24866363	chr5:80050837	5	80050837	MSH3	Open sea	-0.59329	0.00638	3.1000000000000004e-162	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg18434588	chr5:80095132	5	80095132	MSH3	Open sea	0.52685	0.00841	3.1e-130	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.178665	0.00812372	1.691231e-105	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.153089	0.00815925	1.235797e-77	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.150261	0.00816283	7.888515000000001e-75	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01603981	chr5:80043300	5	80043300	MSH3	Open sea	0.09196	0.00317	2.2e-72	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.130569	0.00818589	8.484382e-57	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.12259	0.0081943	3.125599e-50	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22550709	chr5:80023352	5	80023352	MSH3	Open sea	0.0023	None	1.8e-43	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.110058	0.00820641	9.038966e-41	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg24866363	chr5:80050837	5	80050837	MSH3	Open sea	-2.23992	0.09299	2.98e-40	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.108618	0.00820772	9.476260000000001e-40	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.103067	0.0082126	6.089653e-36	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg01603981	chr5:80043300	5	80043300	MSH3	Open sea	2.09234	0.10334	1.13e-34	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.0941253	0.00821992	3.1284969999999997e-30	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0926948	0.00822102	2.294183e-29	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0914766	0.00822195	1.22193e-28	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 2817837 (gene symbol: MSH3)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 2817837 (gene symbol: MSH3)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	None	None	5e-25	None	33752734_Yao-C_gene_expression_of_affymetrix_id__2817837__gene_symbol__msh3__meta-analysis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08923791	chr5:80000868	5	80000868	MSH3	Open sea	0.07255	0.0061	7.8e-25	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0838203	0.00822752	2.707967e-24	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0822872	0.00822857	1.808612e-23	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0775983	0.00823168	4.849511e-21	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0733839	0.00823431	5.595126e-19	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0711369	0.00823565	6.321718e-18	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.070498	0.00823603	1.2427060000000002e-17	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0704268	0.00823607	1.3394130000000001e-17	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0702099	0.0082362	1.682165e-17	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.0698914	0.00823638	2.347511e-17	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0695915	0.00823655	3.2087860000000004e-17	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg24866363	chr5:80050837	5	80050837	MSH3	Open sea	0.23842	0.0296	8.42e-16	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.0660782	0.00823853	0.00000000000000113107	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0660347	0.00823855	0.000000000000001180822	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0649809	0.00823912	0.000000000000003316022	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0641844	0.00823955	0.000000000000007160003	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.063945	0.00823967	0.000000000000009007111	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	1.9	0.253	0.000000000000021	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0625358	0.00824041	0.00000000000003419746	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0621993	0.00824058	0.00000000000004682237	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0617201	0.00824083	0.00000000000007304443	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.025	0.00289	0.000000000000085	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0612541	0.00824107	0.0000000000001122052	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0609279	0.00824123	0.0000000000001512493	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03627071	chr5:79968156	5	79968156	MSH3	Open sea	-0.0599886	0.0082417	0.0000000000003542518	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg18434588	chr5:80095132	5	80095132	MSH3	Open sea	0.001	None	0.00000000000038	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0596826	0.00824185	0.00000000000046612	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0591374	0.00824212	0.000000000000757609	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0590739	0.00824215	0.0000000000008014286	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0589721	0.0082422	0.0000000000008770426	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0585733	0.0082424	0.00000000000124652	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	0.329167	0.0471071	0.000000000002897659	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.057247	0.00824303	0.000000000003946703	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0678617	0.00990725	0.000000000007695348	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.05571	0.00824375	0.00000000001453364	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0556308	0.00824379	0.0000000000155287	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	0.315852	0.0470045	0.00000000001878931	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0542596	0.00824441	0.00000000004819298	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg12826129	chr5:80041461	5	80041461	MSH3	Open sea	0.019	0.0026	0.000000000063	None	32795589_Kyung-WK_eosinophilia_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0539076	0.00824457	0.0000000000641681	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg04186980	chr5:79953697	5	79953697	MSH3	South shelf	-0.01689	0.0026	0.0000000000927	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.0531798	0.00824489	0.0000000001153293	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0531071	0.00824492	0.0000000001222286	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.102013	0.016188	0.0000000003026364	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg24866363	chr5:80050837	5	80050837	MSH3	Open sea	0.00088	None	0.00000000033	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.101071	0.0162192	0.0000000004744463	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.0513083	0.0082457	0.0000000005028133	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	0.0494717	0.00824646	0.000000002030304	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Li M	None	33279932	2020-12-14	Schizophrenia	EFO_0000692	main	Table 1	DNA methylation	Schizophrenia	age, sex, batch effects	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	999	None	Adults	Both	East Asian	cg15612517	chr5:80032595	5	80032595	MSH3	Open sea	0.00678	0.00113	0.0000000021	None	33279932_Li-M_schizophrenia_main
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0492778	0.00824654	0.000000002345883	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	0.0489947	0.00826782	0.000000003174414	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.01552	0.0025	0.0000000033	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.048694	0.00824678	0.000000003612987	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17158445	chr5:79974803	5	79974803	MSH3	Open sea	0.0483881	0.0082469	0.000000004521449	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg16522602	chr5:79964079	5	79964079	MSH3	Open sea	-0.232287	0.0396866	0.000000004909888	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0479001	0.00824709	0.000000006448766	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0477297	0.00824716	0.000000007293928	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0485456	0.00839395	0.000000007469339	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0474865	0.00824726	0.000000008689291	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21350127	chr5:80009604	5	80009604	MSH3	Open sea	0.0474464	0.00824727	0.000000008943258	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0473267	0.00824732	0.000000009744168	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	0.276883	0.0482907	0.000000009992802	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.289107	0.0504411	0.00000001011558	None	39706196_Hannah-M.-Smith_bmi_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.288046	0.0504021	0.00000001115365	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0562025	0.0098386	0.00000001135247	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.046832	0.00824751	0.00000001386064	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16522602	chr5:79964079	5	79964079	MSH3	Open sea	-0.0467584	0.00824754	0.00000001460218	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12826129	chr5:80041461	5	80041461	MSH3	Open sea	0.0467476	0.00824754	0.00000001471353	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0476142	0.0084093	0.00000001523499	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0533427	0.00952957	0.00000002212361	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0461634	0.00824777	0.00000002218985	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0461452	0.00824778	0.00000002247472	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Li M	None	33279932	2020-12-14	Schizophrenia	EFO_0000692	adjusted for cell composition	Table 1	DNA methylation	Schizophrenia	age, sex, batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	999	None	Adults	Both	East Asian	cg15612517	chr5:80032595	5	80032595	MSH3	Open sea	None	None	0.000000025	None	33279932_Li-M_schizophrenia_adjusted_for_cell_composition
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0459532	0.00824785	0.00000002569471	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0529806	0.00954545	0.0000000290036	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	2.4	0.436	0.000000032	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0453503	0.00824808	0.00000003899043	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0886082	0.0161748	0.00000004368308	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03627071	chr5:79968156	5	79968156	MSH3	Open sea	-0.0451604	0.00824815	0.00000004441501	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg01603981	chr5:80043300	5	80043300	MSH3	Open sea	-0.02135	0.0039	0.0000000453	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0450241	0.0082482	0.00000004875365	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0448799	0.00824825	0.00000005379071	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0447032	0.00824832	0.00000006065101	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08923791	chr5:80000868	5	80000868	MSH3	Open sea	0.0011	None	0.000000071	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16522602	chr5:79964079	5	79964079	MSH3	Open sea	0.220507	0.0409186	0.00000007180693	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0442753	0.00824847	0.00000008096329	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03627071	chr5:79968156	5	79968156	MSH3	Open sea	-0.0440706	0.00824855	0.00000009287329	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0530799	0.00994044	0.00000009444021	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03627071	chr5:79968156	5	79968156	MSH3	Open sea	-0.0437458	0.00824867	0.0000001153299	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg24866363	chr5:80050837	5	80050837	MSH3	Open sea	-	-	0.000000116	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0448212	0.00845389	0.0000001163011	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0870977	0.0164397	0.0000001187575	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16522602	chr5:79964079	5	79964079	MSH3	Open sea	0.215573	0.0408265	0.0000001305924	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0433394	0.00824881	0.0000001509048	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16522602	chr5:79964079	5	79964079	MSH3	Open sea	0.0433289	0.00824882	0.0000001519444	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16522602	chr5:79964079	5	79964079	MSH3	Open sea	-0.0450211	0.00857209	0.0000001525169	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.044064	0.00841701	0.0000001671549	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	0.043296	0.00828069	0.000000173194	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.0430306	0.00824892	0.0000001848017	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.225159	0.043184	0.0000001869894	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17158445	chr5:79974803	5	79974803	MSH3	Open sea	0.0430099	0.00824893	0.0000001873295	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.042948	0.00824895	0.0000001950606	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0428552	0.00824899	0.0000002072263	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01603981	chr5:80043300	5	80043300	MSH3	Open sea	0.0012	None	0.00000031	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	0.244138	0.0479894	0.0000003669326	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0419229	0.00824931	0.0000003780914	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	0.0418376	0.00824934	0.0000003992394	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.172927	0.0341014	0.0000003999265	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0558663	0.011048	0.000000431781	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0415771	0.00824943	0.0000004710719	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0414381	0.00824948	0.0000005143772	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0414025	0.00824949	0.0000005260734	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16522602	chr5:79964079	5	79964079	MSH3	Open sea	-0.0429048	0.00856688	0.0000005557593	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.0412668	0.00824954	0.0000005730164	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0412081	0.00824956	0.000000594561	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0410848	0.0082496	0.0000006423345	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.04913	0.00989911	0.0000007016513	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.18	0.0356	0.00000071	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	C9JB55	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	C9JB55	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0492958	0.00995579	0.0000007447559	C9JB55	41361833_Josephine_Robertson_C9JB55_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.168571	0.0340761	0.0000007611771	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0802895	0.0162375	0.0000007711006	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0474079	0.00959149	0.0000007789792	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-1.6	0.332	0.0000008	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0791739	0.016049	0.0000008175876	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0406778	0.00824974	0.0000008278926	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0404503	0.00824981	0.0000009530595	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.0403751	0.00824984	0.0000009983275	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	C9JB55	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	C9JB55	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0486112	0.00994567	0.000001031122	C9JB55	41361833_Josephine_Robertson_C9JB55_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21350127	chr5:80009604	5	80009604	MSH3	Open sea	-0.0402752	0.00824987	0.000001061656	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	-0.22342	0.0457933	0.000001075852	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0402453	0.00824988	0.000001081358	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0793296	0.0163114	0.000001165658	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.0399112	0.00824999	0.000001326705	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.138292	0.0286554	0.000001403929	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0398086	0.00825003	0.000001412217	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0788112	0.0163637	0.000001477568	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03627071	chr5:79968156	5	79968156	MSH3	Open sea	-0.0397236	0.00825005	0.000001487097	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21350127	chr5:80009604	5	80009604	MSH3	Open sea	0.0395296	0.00825012	0.000001672452	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0394906	0.00825013	0.000001712274	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0460252	0.00966499	0.000001934635	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.160633	0.0341831	0.000002632042	None	39706196_Hannah-M.-Smith_body_fat_discovery
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.073	0.0156	0.0000028	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0386122	0.00825041	0.000002893933	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0385744	0.00825043	0.000002959349	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.155038	0.0331641	0.000002962436	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12826129	chr5:80041461	5	80041461	MSH3	Open sea	0.0384616	0.00825046	0.000003162979	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0843531	0.0182738	0.000003944055	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	C9JB55	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	C9JB55	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.105963	0.0229729	0.000004011977	C9JB55	41361833_Josephine_Robertson_C9JB55_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.226104	0.0493593	0.000004663337	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0601378	0.0131287	0.000004673541	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.0390475	0.00857381	0.000005298837	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22550709	chr5:80023352	5	80023352	MSH3	Open sea	-0.00094	0.00021	0.0000053	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0374567	0.00825078	0.000005676082	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0449464	0.00990853	0.000005775073	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0498021	0.0109854	0.000005848066	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0373844	0.0082508	0.00000591688	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.22889	0.0505746	0.000006057319	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.037335	0.00825082	0.0000060868	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.0498022	0.0110301	0.00000637709	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	0.037181	0.00824159	0.000006490398	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.05	0.01113	0.0000072	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0370118	0.00825091	0.000007319806	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.0378927	0.00847271	0.000007795601	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17158445	chr5:79974803	5	79974803	MSH3	Open sea	0.0368874	0.00825095	0.000007855442	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0585342	0.0131314	0.000008350584	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0366456	0.00825103	0.000009005353	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.028	0.00633	0.0000091	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.0378018	0.0085314	0.000009451688	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12826129	chr5:80041461	5	80041461	MSH3	Open sea	0.036499	0.00825107	0.000009779091	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01009	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01009	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0364918	0.00825107	0.000009819103	P01009	41361833_Josephine_Robertson_P01009_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0364803	0.00825108	0.000009882224	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.098121	0.0222084	0.00001002463	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0363883	0.0082511	0.00001040527	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0362556	0.00825114	0.00001120588	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg15276037	chr5:80007159	5	80007159	MSH3	Open sea	0.0362237	0.00825115	0.00001140722	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0360532	0.0082512	0.00001254174	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02787	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02787	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.043456	0.00994852	0.00001262014	P02787	41361833_Josephine_Robertson_P02787_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg17158445	chr5:79974803	5	79974803	MSH3	Open sea	0.0360058	0.00825122	0.00001287584	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.0359576	0.00825123	0.00001322448	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.18808	0.0434746	0.00001525449	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg04186980	chr5:79953697	5	79953697	MSH3	South shelf	-0.00828	0.00187	0.000016	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13629923	chr5:80009668	5	80009668	MSH3	Open sea	-0.0356063	0.00825134	0.0000160494	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0353187	0.00825142	0.00001878066	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0352609	0.00825144	0.00001938137	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21350127	chr5:80009604	5	80009604	MSH3	Open sea	0.0368575	0.00863132	0.0000196526	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03627071	chr5:79968156	5	79968156	MSH3	Open sea	-0.035151	0.00825147	0.00002057262	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0556484	0.013114	0.00002214679	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0409046	0.00964082	0.00002220475	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg02448788	chr5:80057191	5	80057191	MSH3	Open sea	-0.1208345	0.0285025	0.00002241	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.0349392	0.00825153	0.00002306893	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12826129	chr5:80041461	5	80041461	MSH3	Open sea	0.0348883	0.00825155	0.00002371102	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.0354143	0.00838123	0.00002399316	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03627071	chr5:79968156	5	79968156	MSH3	Open sea	-0.034684	0.0082516	0.00002646016	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0740751	0.0176255	0.00002652991	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0538269	0.0128141	0.00002677845	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0344271	0.00825168	0.00003034932	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg12826129	chr5:80041461	5	80041461	MSH3	Open sea	0.034427	0.00825168	0.00003035132	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21350127	chr5:80009604	5	80009604	MSH3	Open sea	-0.0344881	0.0082845	0.0000315936	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.0342972	0.00825171	0.00003251736	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0342785	0.00825172	0.00003284212	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0457103	0.0110341	0.00003452515	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0343084	0.00832222	0.00003768417	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.0453046	0.0110046	0.00003861298	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg04186980	chr5:79953697	5	79953697	MSH3	South shelf	0.0037	0.0009	0.000039	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0677622	0.0164861	0.00003973521	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0675476	0.0164628	0.00004099579	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21350127	chr5:80009604	5	80009604	MSH3	Open sea	-0.033662	0.00825189	0.00004540818	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0404361	0.00992663	0.00004655537	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21350127	chr5:80009604	5	80009604	MSH3	Open sea	-0.0335106	0.00825562	0.00004951235	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05543	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05543	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0334848	0.00825194	0.00004979277	P05543	41361833_Josephine_Robertson_P05543_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	0.0334338	0.00825196	0.00005112669	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02749	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02749	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0930724	0.02299	0.00005183641	P02749	41361833_Josephine_Robertson_P02749_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0333411	0.00825198	0.00005363823	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	0.0331217	0.00825204	0.00006005518	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	0.0331185	0.00825204	0.00006015481	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0330997	0.00825205	0.0000607375	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0397835	0.00992798	0.00006174393	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	-0.0330583	0.00825206	0.00006204298	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0329769	0.00825208	0.00006468337	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0733493	0.0183568	0.00006480464	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0651406	0.0163644	0.0000690641	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16522602	chr5:79964079	5	79964079	MSH3	Open sea	0.0338768	0.00851368	0.00006950816	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16522602	chr5:79964079	5	79964079	MSH3	Open sea	-0.0562472	0.0141402	0.00006988368	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg24866363	chr5:80050837	5	80050837	MSH3	Open sea	-0.001	0.00025	0.00007	None	33564054_Kashima-K_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21350127	chr5:80009604	5	80009604	MSH3	Open sea	0.0329577	0.00830195	0.00007225512	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0326977	0.00825216	0.00007457758	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	0.0646912	0.0163705	0.00007796524	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0325888	0.00825219	0.00007880683	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P19652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P19652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0325293	0.0082522	0.00008121758	P19652	41361833_Josephine_Robertson_P19652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13629923	chr5:80009668	5	80009668	MSH3	Open sea	0.0324704	0.00825222	0.0000836678	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH38	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH38	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg21350127	chr5:80009604	5	80009604	MSH3	Open sea	0.0326417	0.00830052	0.00008445963	A0A0C4DH38	41361833_Josephine_Robertson_A0A0C4DH38_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0324121	0.00825223	0.00008616462	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0431655	0.0110164	0.00008958524	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg14609862	chr5:80121879	5	80121879	MSH3	Open sea	-0.0323051	0.00825226	0.00009092866	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0323025	0.00825226	0.00009104611	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00926855	chr5:80037111	5	80037111	MSH3	Open sea	-0.032296	0.00825226	0.00009134187	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg07324116	chr5:80060102	5	80060102	MSH3	Open sea	0.0386734	0.00989177	0.00009284454	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16522602	chr5:79964079	5	79964079	MSH3	Open sea	0.0322276	0.00825228	0.00009453424	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg04349497	chr5:80162419	5	80162419	MSH3	Open sea	-0.0643942	0.0165048	0.00009601104	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10551122	chr5:80167586	5	80167586	MSH3	Open sea	-0.0321739	0.0082523	0.00009710817	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_1