author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09160751	chr16:70190329	16	70190329	PDPR	Open sea	0.002	0.00021	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09160751	chr16:70190329	16	70190329	PDPR	Open sea	-0.013	0.0014	0	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	ch.16.1562336F	chr16:70172531	16	70172531	PDPR	Open sea	0.0014	0.00011	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg01577529	chr16:70190513	16	70190513	PDPR	Open sea	None	None	5.3e-284	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3667093__gene_symbol__pdpr__meta-analysis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg08479294	chr16:70193705	16	70193705	PDPR	Open sea	None	None	9.4e-145	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3667093__gene_symbol__pdpr__meta-analysis
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg07381228	chr16:70190398	16	70190398	PDPR	Open sea	None	None	2.4e-118	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3667093__gene_symbol__pdpr__meta-analysis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg08479294	chr16:70193705	16	70193705	PDPR	Open sea	0.11089	0.00441	9.8e-63	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg03181373	chr16:70151549	16	70151549	PDPR	South shelf	0.0648	0.00345	2.1e-45	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg13253791	chr16:70148758	16	70148758	PDPR	Island	None	None	7.100000000000001e-36	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3667093__gene_symbol__pdpr__meta-analysis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01577529	chr16:70190513	16	70190513	PDPR	Open sea	0.03594	0.00261	1.9999999999999998e-30	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg09160751	chr16:70190329	16	70190329	PDPR	Open sea	-0.04747	0.00361	1.4000000000000001e-28	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07379344	chr16:70147964	16	70147964	PDPR	Island	0.01139	0.00096	1.0000000000000001e-24	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg09160751	chr16:70190329	16	70190329	PDPR	Open sea	None	None	3.2e-20	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3667093__gene_symbol__pdpr__meta-analysis
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg03181373	chr16:70151549	16	70151549	PDPR	South shelf	-0.024	0.00221	1.9e-18	None	32795589_Kyung-WK_eosinophilia_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07381228	chr16:70190398	16	70190398	PDPR	Open sea	0.0012	None	6.3e-17	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3667093 (gene symbol: PDPR)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg05690286	chr16:70148511	16	70148511	PDPR	Island	None	None	0.000000000000025	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3667093__gene_symbol__pdpr__meta-analysis
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg03181373	chr16:70151549	16	70151549	PDPR	South shelf	-0.011	0.00123	0.000000000000055	None	32795589_Kyung-WK_atopy_discovery
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg19581275	chr16:70146610	16	70146610	PDPR	North shore	-0.00986	0.0016	0.000000000448	-	23334450_rheumatoid_arthritis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg13253791	chr16:70148758	16	70148758	PDPR	Island	0.00987	0.00156	0.0000000016	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	ch.16.1562336F	chr16:70172531	16	70172531	PDPR	Open sea	0.00081	None	0.0000000074	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09160751	chr16:70190329	16	70190329	PDPR	Open sea	0.0015	None	0.000000035	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08884568	chr16:70185914	16	70185914	PDPR	Open sea	-0.0446253	0.00824835	0.00000006393796	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13253791	chr16:70148758	16	70148758	PDPR	Island	0.00035	0.000064	0.000000075	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19581275	chr16:70146610	16	70146610	PDPR	North shore	-0.00031	0.000058	0.00000011	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg13253791	chr16:70148758	16	70148758	PDPR	Island	0.171268	0.0327288	0.0000001686766	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07381228	chr16:70190398	16	70190398	PDPR	Open sea	0.0034	None	0.00000022	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	ch.16.1562336F	chr16:70172531	16	70172531	PDPR	Open sea	0.0034	0.00068	0.00000041	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08884568	chr16:70185914	16	70185914	PDPR	Open sea	-0.038794	0.00825036	0.000002598419	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg07381228	chr16:70190398	16	70190398	PDPR	Open sea	-0.215602	0.0471324	0.000004807262	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09160751	chr16:70190329	16	70190329	PDPR	Open sea	0.0062	0.0014	0.0000063	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	MYOC protein levels (SeqId = 16558-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MYOC protein levels (SeqId = 16558-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Myocilin	774	1	Adults (18-65 years)	Both	European	cg07381228	chr16:70190398	16	70190398	PDPR	Open sea	1.07	0.245	0.000014	None	Gadd-DA_myoc_protein_levels__seqid___16558-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08884568	chr16:70185914	16	70185914	PDPR	Open sea	-0.0356469	0.00825132	0.00001569508	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13253791	chr16:70148758	16	70148758	PDPR	Island	0.0607968	0.014269	0.00002050117	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg08884568	chr16:70185914	16	70185914	PDPR	Open sea	-0.0347872	0.00825157	0.00002503627	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	COL3A1 protein levels (SeqId = 18880-81)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COL3A1 protein levels (SeqId = 18880-81)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen alpha-1(III) chain	774	1	Adults (18-65 years)	Both	European	cg08884568	chr16:70185914	16	70185914	PDPR	Open sea	0.77	0.185	0.00003	None	Gadd-DA_col3a1_protein_levels__seqid___18880-81__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg13253791	chr16:70148758	16	70148758	PDPR	Island	0.0017	0.00042	0.000042	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	TPPP2 protein levels (SeqId = 12800-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TPPP2 protein levels (SeqId = 12800-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tubulin polymerization-promoting protein family member 2	774	1	Adults (18-65 years)	Both	European	cg07381228	chr16:70190398	16	70190398	PDPR	Open sea	0.97	0.247	0.000082	None	Gadd-DA_tppp2_protein_levels__seqid___12800-5__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Neutrophils	Table S2	DNA methylation	HIV infection	Age	-	-	Illumina HumanMethylation450	Neutrophils	-	60	1	46.5	Males	European	cg07235439	chr16:70148795	16	70148795	PDPR	South shore	-0.20159	0.0515	0.000091	-	27105112_hiv_infection_neutrophils