author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg06761377	chr1:16062757	1	16062757	SLC25A34	Open sea	0.50324	0.00607	6.8e-153	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg19916794	chr1:16061408	1	16061408	SLC25A34	South shelf	0.42605	0.00598	1.3e-140	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg21821674	chr1:16063471	1	16063471	SLC25A34	Open sea	0.47672	0.00685	1.2e-138	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg09028651	chr1:16061414	1	16061414	SLC25A34	South shelf	0.64144	0.00947	2e-136	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg10881110	chr1:16062737	1	16062737	SLC25A34	Open sea	0.4389	0.00677	5.5000000000000005e-133	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.28101	0.00451	7.9e-130	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02485345	chr1:16061554	1	16061554	SLC25A34	South shelf	0.33612	0.00582	8.4e-124	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	0.23381	0.00405	1.1e-123	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg16713727	chr1:16062720	1	16062720	SLC25A34	Open sea	0.47727	0.00871	1.2e-119	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg15616400	chr1:16062894	1	16062894	SLC25A34	Open sea	0.25599	0.00514	4.1e-112	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg03970032	chr1:16062915	1	16062915	SLC25A34	Open sea	0.17108	0.00404	1.3e-99	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.123953	0.0081929	2.528163e-51	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg15616400	chr1:16062894	1	16062894	SLC25A34	Open sea	2.12727	0.07197	3.78e-47	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	2.02895	0.07047	3.03e-46	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg03970032	chr1:16062915	1	16062915	SLC25A34	Open sea	2.25984	0.08369	4.57e-44	-	25282492_fetal_vs_adult_liver
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg21821674	chr1:16063471	1	16063471	SLC25A34	Open sea	1.63539	0.07149	1.45e-38	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.105514	0.00821048	1.351503e-37	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg06761377	chr1:16062757	1	16062757	SLC25A34	Open sea	1.25876	0.0654	4.17e-33	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.094081	0.00821995	3.329339e-30	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg16713727	chr1:16062720	1	16062720	SLC25A34	Open sea	1.5718	0.09143	1.0200000000000001e-29	-	25282492_fetal_vs_adult_liver
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg09028651	chr1:16061414	1	16061414	SLC25A34	South shelf	-	-	6.580000000000001e-27	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0873098	0.00822504	3.1554189999999996e-26	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Bonder MJ	-	25282492	2014-10-04	Fetal vs adult liver	UBERON_0002107, GO_0048513	-	Additional file 2	DNA methylation	Fetal vs adult liver	Sex and technical covariates	M values	-	Illumina HumanMethylation450	Liver	-	195	2	-	Missing	None	cg19916794	chr1:16061408	1	16061408	SLC25A34	South shelf	1.48929	0.09847	4.45e-26	-	25282492_fetal_vs_adult_liver
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0840852	0.00822733	1.943695e-24	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02485345	chr1:16061554	1	16061554	SLC25A34	South shelf	0.001	None	2.3e-23	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0853295	0.0105166	5.292206e-16	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0667251	0.00823817	5.950074e-16	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg16713727	chr1:16062720	1	16062720	SLC25A34	Open sea	-0.0013	0.00016	8.9e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0659219	0.00823861	0.000000000000001319765	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0827827	0.0105667	0.000000000000005038112	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0641141	0.00823958	0.000000000000007659441	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0637951	0.00823975	0.00000000000001039463	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10483611	chr1:16064182	1	16064182	SLC25A34	Open sea	-0.48566	0.0685023	0.000000000001396017	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0572249	0.00824304	0.000000000004022177	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0722396	0.0105268	0.000000000007041134	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0562732	0.00824349	0.000000000009050323	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	2.4	0.351	0.000000000011	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Kyung WK	None	32795589	11-08-2020	atopy	EFO_0002686	discovery	Table E4	DNA methylation	atopy	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	108	1	Adults	Both	East Asian	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.032	0.00424	0.000000000012	None	32795589_Kyung-WK_atopy_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0548821	0.00824413	0.00000000002891665	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0547926	0.00824417	0.00000000003113055	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0690115	0.0103838	0.00000000003115984	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0671778	0.0105852	0.0000000002269115	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0508225	0.0082459	0.0000000007307782	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0650401	0.0105623	0.0000000007569614	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0507636	0.00824593	0.000000000764491	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0501898	0.00824617	0.000000001183244	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0494195	0.00824648	0.000000002110863	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.00087	0.00014	0.0000000022	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0490542	0.00824663	0.0000000027695	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0628937	0.0105893	0.000000002926121	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0480555	0.00824703	0.00000000576134	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0668191	0.0114935	0.000000006239005	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg19916794	chr1:16061408	1	16061408	SLC25A34	South shelf	0.15236	0.0266	0.0000000104	-	25650246_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0470493	0.00824743	0.00000001187844	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.046577	0.00824761	0.00000001659783	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Spiers H	-	25650246	2015-02-03	Gestational age	EFO_0005112, EFO_0000246	-	Additional file 1	DNA methylation	Gestational age	Sex and technical covariates	Beta values	days	Illumina HumanMethylation450	Fetal brain	-	179	1	-	Both	None	cg09028651	chr1:16061414	1	16061414	SLC25A34	South shelf	0.14942	0.0265	0.0000000181	-	25650246_gestational_age
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.30799	0.0552877	0.00000002575304	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06761377	chr1:16062757	1	16062757	SLC25A34	Open sea	-0.381598	0.0685705	0.00000002659631	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09028651	chr1:16061414	1	16061414	SLC25A34	South shelf	-0.00033	0.00006	0.000000035	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0582578	0.0105624	0.0000000353458	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg19916794	chr1:16061408	1	16061408	SLC25A34	South shelf	-	-	0.0000000365	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0452279	0.00824812	0.00000004240732	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0617612	0.0114258	0.00000006567701	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg05510104	chr1:16062735	1	16062735	SLC25A34	Open sea	-0.182674	0.0338276	0.00000006742352	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0439382	0.0082486	0.0000001014658	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0437572	0.00824866	0.0000001144565	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0051	0.00097	0.00000012	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JMB2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JMB2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0551326	0.010567	0.0000001838973	A0A0G2JMB2	41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg19916794	chr1:16061408	1	16061408	SLC25A34	South shelf	-0.0061	0.0012	0.00000022	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10881110	chr1:16062737	1	16062737	SLC25A34	Open sea	-0.00075	0.00015	0.00000024	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0424013	0.00824915	0.0000002781436	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0421736	0.00824923	0.0000003220473	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg16713727	chr1:16062720	1	16062720	SLC25A34	Open sea	-0.202724	0.039825	0.000000360948	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg15616400	chr1:16062894	1	16062894	SLC25A34	Open sea	-0.210129	0.0416434	0.0000004556942	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	0.0413981	0.00824949	0.0000005275228	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.00049061	9.75e-05	0.000000576	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	-0.0410878	0.0082496	0.0000006411539	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0519566	0.0104809	0.0000007228984	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0520799	0.0105511	0.0000008063977	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg10483611	chr1:16064182	1	16064182	SLC25A34	Open sea	-0.33643	0.0689992	0.00000109298	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0399872	0.00824997	0.000001266565	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0398627	0.00825001	0.000001366504	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg09028651	chr1:16061414	1	16061414	SLC25A34	South shelf	0.00038	None	0.0000015	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	-0.0008	0.00017	0.0000016	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0393992	0.00825016	0.000001809347	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	-0.0392151	0.00825022	0.000002020982	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	-0.0390473	0.00825027	0.000002234624	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Battram T	GEO	30529013	2020-11-01	Melanoma	EFO_0000756	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE120878. Authors assessed methylation differences between melanoma samples and nevi	None	DNA methylation	Melanoma	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Skin	None	162	1	Adults	Both	Unclear	cg15616400	chr1:16062894	1	16062894	SLC25A34	Open sea	0.12	0.0244	0.0000023	None	30529013_Battram-T_melanoma_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse120878__authors_assessed_methylation_differences_between_melanoma_samples_and_nevi
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.054	0.01142	0.0000024	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0386054	0.00825042	0.00000290557	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0385834	0.00825042	0.000002943692	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0385311	0.00825044	0.000003036023	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg06761377	chr1:16062757	1	16062757	SLC25A34	Open sea	0.0013	None	0.0000033	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg06761377	chr1:16062757	1	16062757	SLC25A34	Open sea	-0.22637	0.0486926	0.000003359593	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02485345	chr1:16061554	1	16061554	SLC25A34	South shelf	-0.00048	0.0001	0.0000038	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg10483611	chr1:16064182	1	16064182	SLC25A34	Open sea	0.251585	0.054534	0.000003988844	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg16713727	chr1:16062720	1	16062720	SLC25A34	Open sea	0.0389279	0.00844716	0.000004092003	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.254835	0.0553465	0.000004166851	None	39706196_Hannah-M.-Smith_bmi_discovery
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg09848498	chr1:16063649	1	16063649	SLC25A34	Open sea	0.0911606	0.019831	0.000004289	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16713727	chr1:16062720	1	16062720	SLC25A34	Open sea	0.187197	0.0408044	0.000004513889	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0375447	0.00825075	0.000005395802	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06761377	chr1:16062757	1	16062757	SLC25A34	Open sea	0.0373499	0.00825081	0.000006034874	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03420647	chr1:16064239	1	16064239	SLC25A34	Open sea	-0.0368969	0.00815973	0.000006179016	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0519479	0.01149	0.000006198607	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03970032	chr1:16062915	1	16062915	SLC25A34	Open sea	0.0012	None	0.0000063	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.26	0.0579	0.0000064	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0827302	0.0185216	0.000008003271	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0367814	0.00825098	0.000008341336	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	-0.0365962	0.00825104	0.000009259397	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0467425	0.0105856	0.00001014241	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06761377	chr1:16062757	1	16062757	SLC25A34	Open sea	-0.302855	0.0687873	0.00001075157	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0362841	0.00825113	0.00001102943	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	-0.0362399	0.00825115	0.0000113043	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0529141	0.0120517	0.00001138266	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg13416916	chr1:16064650	1	16064650	SLC25A34	Open sea	-0.288588	0.0659288	0.00001208842	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0523656	0.0119895	0.00001264795	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0499596	0.0114852	0.00001371207	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	DPEP1 protein levels (SeqId = 8794-13)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPEP1 protein levels (SeqId = 8794-13)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dipeptidase 1	774	1	Adults (18-65 years)	Both	European	cg06761377	chr1:16062757	1	16062757	SLC25A34	Open sea	1.1	0.255	0.000015	None	Gadd-DA_dpep1_protein_levels__seqid___8794-13__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.053417	0.0123573	0.00001551339	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0356436	0.00825132	0.00001572406	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0355364	0.00825136	0.00001667592	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10881110	chr1:16062737	1	16062737	SLC25A34	Open sea	0.00089	None	0.000017	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.04479	0.0104797	0.00001932166	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0450997	0.0105867	0.00002056761	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.23626	0.0554781	0.00002067775	None	39706196_Hannah-M.-Smith_body_fat_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.268807	0.0633976	0.00002246029	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0347724	0.00825158	0.00002523511	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	0.0347253	0.00825159	0.00002588068	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg03575366	chr1:16062729	1	16062729	SLC25A34	Open sea	-0.190201	0.0452819	0.00002677408	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg19916794	chr1:16061408	1	16061408	SLC25A34	South shelf	-0.169652	0.0403999	0.00002689904	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09848498	chr1:16063649	1	16063649	SLC25A34	Open sea	0.0351109	0.00837977	0.00002806332	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.034426	0.00825168	0.00003036756	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09848498	chr1:16063649	1	16063649	SLC25A34	Open sea	-0.034219	0.00823283	0.00003251323	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09848498	chr1:16063649	1	16063649	SLC25A34	Open sea	-0.162005	0.0390431	0.00003348748	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0502198	0.0121291	0.00003485689	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13971	1	Adults (18-65y)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.05	0.01217	0.000035	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0341501	0.00825176	0.0000351499	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15616400	chr1:16062894	1	16062894	SLC25A34	Open sea	-0.255705	0.0619582	0.00003691537	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	0.0340171	0.00825179	0.00003770189	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04275	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04275	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.0339554	0.00825181	0.00003894487	P04275	41361833_Josephine_Robertson_P04275_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg10881110	chr1:16062737	1	16062737	SLC25A34	Open sea	-0.214734	0.0525615	0.0000441918	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg05510104	chr1:16062735	1	16062735	SLC25A34	Open sea	0.141294	0.034684	0.00004647132	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	-0.0336175	0.0082519	0.00004647413	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg15616400	chr1:16062894	1	16062894	SLC25A34	Open sea	-0.252755	0.0621341	0.00004765143	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.0429064	0.0105731	0.00004973284	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0425192	0.010527	0.00005393816	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09848498	chr1:16063649	1	16063649	SLC25A34	Open sea	0.0522136	0.0129392	0.00005481143	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10483611	chr1:16064182	1	16064182	SLC25A34	Open sea	-0.0340752	0.00846295	0.00005692287	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	-0.293477	0.0729224	0.00005733658	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Gadd DA	Generation Scotland	35945220	31/07/2022	TCL1A protein levels (SeqId = 17210-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TCL1A protein levels (SeqId = 17210-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: T-cell leukemia/lymphoma protein 1A	774	1	Adults (18-65 years)	Both	European	cg09848498	chr1:16063649	1	16063649	SLC25A34	Open sea	-0.86	0.215	0.000063	None	Gadd-DA_tcl1a_protein_levels__seqid___17210-2__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg16713727	chr1:16062720	1	16062720	SLC25A34	Open sea	0.163173	0.0408422	0.00006490236	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0329693	0.00825208	0.00006493452	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	0.250801	0.0631713	0.00007209795	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.048984	0.0123394	0.0000722988	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03575366	chr1:16062729	1	16062729	SLC25A34	Open sea	0.183563	0.0463088	0.00007403351	None	39706196_Hannah-M.-Smith_bmi_discovery
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03970032	chr1:16062915	1	16062915	SLC25A34	Open sea	-0.00077	0.0002	0.000077	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10483611	chr1:16064182	1	16064182	SLC25A34	Open sea	0.0333455	0.00843443	0.00007738071	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09662329	chr1:16062445	1	16062445	SLC25A34	South shelf	-0.0418169	0.0105882	0.00007871703	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg09848498	chr1:16063649	1	16063649	SLC25A34	Open sea	0.0332235	0.00841405	0.00007898554	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Jeong A	SAPALDIA	34689037	Oct 21, 2021	NDVI of 500 m circular buffer surrounding residential address	None	None	None	DNA methylation	NDVI of 500 m circular buffer surrounding residential address	Age, Sex, Smoking, Cell composition (reference free), Socio-economic position, Education, study area, second-hand smoking, air pollution, transportation noise, season of blood draw	Other	None	Illumina HumanMethylation450	Whole blood	None	982	None	Adults (18-65 years)	Both	European	cg06761377	chr1:16062757	1	16062757	SLC25A34	Open sea	-0.0232	0.00589	0.000083	None	34689037_Jeong-A_ndvi_of_500_m_circular_buffer_surrounding_residential_address
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P13671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P13671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05337019	chr1:16062361	1	16062361	SLC25A34	South shelf	-0.032444	0.00825222	0.00008478945	P13671	41361833_Josephine_Robertson_P13671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg10881110	chr1:16062737	1	16062737	SLC25A34	Open sea	-0.0322454	0.00825879	0.00009488996	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg26923754	chr1:16063122	1	16063122	SLC25A34	Open sea	-0.0321698	0.0082523	0.00009730873	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg13416916	chr1:16064650	1	16064650	SLC25A34	Open sea	-0.0321464	0.0082523	0.00009845535	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
