author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02264943	chr11:130785842	11	130785842	SNX19	North shore	-0.0012	0.00012	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.0011	0.00011	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22079354	chr11:130786696	11	130786696	SNX19	South shore	-0.0016	0.00016	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg26902026	chr11:130785536	11	130785536	SNX19	North shore	0.3941	0.00485	3.7e-151	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg07740705	chr11:130746300	11	130746300	SNX19	Open sea	0.30001	0.0059	9.9e-114	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.156723	0.00815454	2.554537e-81	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	4.6	0.257	2.3e-70	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.144727	0.00816964	1.692143e-69	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.679854	0.0385008	3.562226e-69	None	39706196_Hannah-M.-Smith_bmi_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.655799	0.0386146	3.623042e-64	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.183567	0.0113868	5.713409e-58	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.60841	0.0385394	9.414703999999999e-56	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.13083	0.00593	1.1e-54	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.176956	0.0114226	1.049556e-53	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02264943	chr11:130785842	11	130785842	SNX19	North shore	0.06946	0.00338	1.9e-50	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.616474	0.0419152	1.133767e-48	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.166526	0.0114317	9.798386999999999e-48	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.118951	0.00819795	2.235279e-47	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.610158	0.0421956	4.07239e-47	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.166372	0.0121389	1.717256e-42	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.1	0.00804	2.2e-37	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.153996	0.0121182	8.362007e-37	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg14779329	chr11:130786720	11	130786720	SNX19	South shore	0.08481	0.00544	5e-36	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.511046	0.0421169	9.570017e-34	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.135637	0.0112896	4.270478e-33	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.130242	0.0111175	1.474759e-31	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.141495	0.0124328	6.965116999999999e-30	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0935471	0.00822037	7.025935e-30	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.12948	0.0114494	1.571739e-29	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.134567	0.0119258	2.088561e-29	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	0.001	None	3.7e-28	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0895477	0.0082234	1.6504390000000002e-27	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.130968	0.0122132	9.925464000000001e-27	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0865517	0.00822559	8.42983e-26	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.129495	0.0124029	1.984218e-25	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0805498	0.00822974	1.4913980000000002e-22	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg22079354	chr11:130786696	11	130786696	SNX19	South shore	0.0318	0.00288	2.4e-22	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.110221	0.0114787	9.067017e-22	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.109335	0.0114831	1.971289e-21	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.107191	0.0113756	5.031863e-21	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.108892	0.011584	6.236659e-21	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.358055	0.0381609	7.176606e-21	None	39706196_Hannah-M.-Smith_glucose_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.107151	0.0114588	9.915805e-21	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.10633	0.0114594	1.949152e-20	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	sensitivity	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.381175	0.0412284	2.5947339999999998e-20	None	39706196_Hannah-M.-Smith_total_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.1028	0.0114441	2.956215e-19	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	sensitivity	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.376164	0.0418932	2.994673e-19	None	39706196_Hannah-M.-Smith_glucose_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.102931	0.0114678	3.152576e-19	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	-0.0739029	0.00823399	3.1623429999999995e-19	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.101322	0.0113351	4.395939e-19	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	-0.0734526	0.00823427	5.189512e-19	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0733159	0.00823435	6.028216999999999e-19	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.101997	0.0114829	7.289677999999999e-19	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13971	1	Adults (18-65y)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.076	0.00863	9.7e-19	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0994875	0.0114648	4.460089e-18	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0993005	0.0114807	5.709242e-18	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0979915	0.0113734	7.641582e-18	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0970063	0.0112791	8.727676e-18	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0987593	0.0114993	9.709404e-18	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_2
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3398482 (gene symbol: SNX19)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3398482 (gene symbol: SNX19)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg08912652	chr11:130779479	11	130779479	SNX19	Open sea	None	None	1.3e-17	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3398482__gene_symbol__snx19__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0691519	0.00823681	5.0606290000000007e-17	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0962371	0.0114921	6.060322e-17	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01042	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01042	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0688785	0.00823696	6.70898e-17	P01042	41361833_Josephine_Robertson_P01042_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18005	1	Adults (18-65y)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.15	0.0179	8.2e-17	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0876456	0.0105391	9.872127000000001e-17	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.103144	0.0124596	1.357388e-16	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.067988	0.00823747	1.668157e-16	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0937819	0.0114751	3.262806e-16	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg08912652	chr11:130779479	11	130779479	SNX19	Open sea	-0.0027	0.00033	4.4e-16	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	-0.0667877	0.00823814	5.590012e-16	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0897215	0.0113083	0.00000000000000227313	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0901818	0.0114147	0.000000000000002974404	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0649666	0.00823913	0.000000000000003362475	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Total cholesterol	EFO_0004574	discovery	None	DNA methylation	Total cholesterol	Age,Sex,Smoking,Cell composition (reference based)	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18270	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.292738	0.0375997	0.000000000000007304191	None	39706196_Hannah-M.-Smith_total_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0961352	0.0124224	0.00000000000001068539	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_4
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	2.1	0.272	0.000000000000013	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0868144	0.0113655	0.00000000000002334441	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0880772	0.0115912	0.00000000000003173298	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0942118	0.0124197	0.00000000000003506714	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14779329	chr11:130786720	11	130786720	SNX19	South shore	-0.019	0.0025	0.000000000000054	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0862412	0.0114597	0.00000000000005553698	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_2
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3398482 (gene symbol: SNX19)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3398482 (gene symbol: SNX19)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg22079354	chr11:130786696	11	130786696	SNX19	South shore	None	None	0.0000000000002	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3398482__gene_symbol__snx19__meta-analysis
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg10101263	chr11:130786633	11	130786633	SNX19	Island	0.01034	0.0014	0.000000000000262	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0839794	0.0115034	0.0000000000003017024	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0835634	0.0115064	0.000000000000399659	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	-0.0598283	0.00824178	0.0000000000004091144	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Liu Y	-	23334450	2013-01-20	Rheumatoid arthritis	EFO_0000685	-	Table S3	DNA methylation	Rheumatoid arthritis	Age, sex, smoking and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	691	1	51.9	Both	European	cg11399053	chr11:130781648	11	130781648	SNX19	Open sea	0.02328	0.0032	0.000000000000414	-	23334450_rheumatoid_arthritis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0596427	0.00824187	0.0000000000004830533	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0899188	0.0124345	0.0000000000005017331	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0818131	0.011487	0.000000000001111146	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.058487	0.00824244	0.000000000001344653	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.266899	0.0377111	0.000000000001521542	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.080782	0.0115	0.000000000002242924	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	0.0029	None	0.0000000000029	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0802801	0.0115831	0.000000000004359293	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_3
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3398482 (gene symbol: SNX19)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3398482 (gene symbol: SNX19)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg14779329	chr11:130786720	11	130786720	SNX19	South shore	None	None	0.0000000000044	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3398482__gene_symbol__snx19__meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.082349	0.0119427	0.000000000005592467	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0788156	0.0114736	0.000000000006711443	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg10101263	chr11:130786633	11	130786633	SNX19	Island	-0.00023	0.000033	0.000000000008	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0835557	0.0124435	0.00000000001952319	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0773687	0.0115374	0.00000000002074702	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0808665	0.0120708	0.0000000000217012	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0766912	0.011486	0.00000000002528173	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Li M	None	33279932	2020-12-14	Schizophrenia	EFO_0000692	adjusted for cell composition	Table 1	DNA methylation	Schizophrenia	age, sex, batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	999	None	Adults	Both	East Asian	cg07740705	chr11:130746300	11	130746300	SNX19	Open sea	None	None	0.00000000003	None	33279932_Li-M_schizophrenia_adjusted_for_cell_composition
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0545043	0.0082443	0.00000000003945168	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.286407	0.0433508	0.00000000004043463	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0543088	0.00824439	0.0000000000462944	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23642342	chr11:130786350	11	130786350	SNX19	Island	0.00032	None	0.000000000047	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0539687	0.00824454	0.00000000006106491	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0803736	0.0123452	0.00000000007734157	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0746446	0.0114907	0.00000000008507702	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Li M	None	33279932	2020-12-14	Schizophrenia	EFO_0000692	main	Table 1	DNA methylation	Schizophrenia	age, sex, batch effects	Beta Values	None	Illumina HumanMethylationEPIC	Whole blood	None	999	None	Adults	Both	East Asian	cg07740705	chr11:130746300	11	130746300	SNX19	Open sea	-0.01773	0.00275	0.00000000011	None	33279932_Li-M_schizophrenia_main
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0725332	0.0114688	0.0000000002616423	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0765919	0.0122024	0.0000000003553676	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0723443	0.0115369	0.0000000003694677	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_3
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg02264943	chr11:130785842	11	130785842	SNX19	North shore	-	-	0.000000000405	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0720029	0.0115468	0.0000000004619179	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	-0.0511726	0.00824575	0.0000000005583314	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0708926	0.0114881	0.0000000006966541	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	-0.00087	0.00014	0.00000000073	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0711321	0.0115833	0.0000000008415785	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.074287	0.0121105	0.000000000878569	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19607663	chr11:130761158	11	130761158	SNX19	Open sea	-0.0505597	0.00824601	0.0000000008933645	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0503342	0.00824611	0.000000001060532	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0501772	0.00824617	0.000000001194541	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0751924	0.0123597	0.000000001203883	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0499531	0.00824626	0.000000001414897	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	-0.0499407	0.00824627	0.000000001428139	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0497004	0.00824637	0.000000001710971	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.073584	0.0122298	0.000000001821792	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17749	1	Adults (18-65y)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.054	0.00896	0.0000000019	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0748844	0.0124726	0.00000000197177	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.068996	0.0115012	0.000000002031971	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0688151	0.0114723	0.000000002039908	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0687899	0.0114992	0.00000000225345	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.048991	0.00824666	0.000000002902074	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0482936	0.00824694	0.000000004844409	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02765	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02765	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0482457	0.00824696	0.000000005016731	P02765	41361833_Josephine_Robertson_P02765_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg11399053	chr11:130781648	11	130781648	SNX19	Open sea	0.0011	None	0.0000000079	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0475405	0.00824724	0.000000008358695	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0471821	0.00824738	0.0000000108054	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0470998	0.00824741	0.0000000114581	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	-0.0520784	0.00915839	0.00000001322171	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19607663	chr11:130761158	11	130761158	SNX19	Open sea	-0.0468469	0.00824751	0.00000001371485	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0658131	0.0115971	0.00000001413629	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0467344	0.00824755	0.00000001485174	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0464396	0.00824766	0.0000000182844	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0494501	0.00878343	0.00000001835906	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.046392	0.00824768	0.00000001890561	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0642221	0.0114662	0.0000000216959	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	-0.0461831	0.00824776	0.00000002188596	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0696892	0.0124962	0.00000002492928	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_4
Imgenberg-Kreuz J	-	26857698	2016-11-01	Primary Sjogrens syndrome	EFO_0000699	Whole blood	Table S1	DNA methylation	Primary Sjogrens syndrome	Age, sex and cell counts	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	-	Both	European	cg07740705	chr11:130746300	11	130746300	SNX19	Open sea	-	-	0.0000000257	-	26857698_primary_sjogrens_syndrome_whole_blood
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0687761	0.0123527	0.00000002626497	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.063985	0.0115111	0.00000002767657	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00747	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00747	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0634143	0.0114898	0.00000003463381	P00747	41361833_Josephine_Robertson_P00747_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17483	1	Adults (18-65y)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.043	0.00773	0.000000036	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	-0.045296	0.0082481	0.00000004047321	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.23819	0.0434016	0.00000004121297	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0677977	0.01238	0.00000004412162	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P80108	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P80108	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0633123	0.0115753	0.0000000458398	P80108	41361833_Josephine_Robertson_P80108_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0684531	0.0125233	0.00000004677053	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0446151	0.00824835	0.00000006438228	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg05974695	chr11:130786536	11	130786536	SNX19	Island	-0.000046	0.0000085	0.000000068	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0471852	0.00876257	0.00000007362079	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P29622	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P29622	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.06705	0.0124599	0.00000007510643	P29622	41361833_Josephine_Robertson_P29622_OSCA_model_4
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg00458607	chr11:130763724	11	130763724	SNX19	Open sea	0.01126	0.00201	0.000000076	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0604026	0.011265	0.00000008357044	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	-0.0441682	0.00824851	0.00000008699713	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O14791	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O14791	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.044144	0.00824852	0.0000000884223	O14791	41361833_Josephine_Robertson_O14791_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0661268	0.0123579	0.00000008879926	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0608914	0.0114517	0.0000001068959	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0607511	0.0114874	0.0000001250831	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0596858	0.0112954	0.0000001281377	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.05918	0.0112111	0.0000001319424	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0658961	0.0125302	0.0000001469098	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0643569	0.0122413	0.0000001481869	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0460582	0.00878347	0.000000159547	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.22791	0.0435043	0.0000001635174	None	39706196_Hannah-M.-Smith_body_fat_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02765	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02765	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0598728	0.0115138	0.0000002018555	P02765	41361833_Josephine_Robertson_P02765_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0426392	0.00824906	0.0000002384776	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0426025	0.00824908	0.0000002442116	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_1
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F4	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	1799	1	60	Both	European	cg14779329	chr11:130786720	11	130786720	SNX19	South shore	-	-	0.000000297	-	26500701_sex_kora_f4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P36955	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P36955	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0582032	0.0113656	0.0000003077676	P36955	41361833_Josephine_Robertson_P36955_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0579117	0.0113293	0.0000003233278	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0580826	0.0113765	0.0000003340936	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0586142	0.0115133	0.0000003606131	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19607663	chr11:130761158	11	130761158	SNX19	Open sea	-0.041963	0.0082493	0.000000368531	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0632867	0.0124866	0.0000004061185	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06727	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06727	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0416734	0.0082494	0.0000004431805	P06727	41361833_Josephine_Robertson_P06727_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	-0.0464676	0.00921791	0.0000004685904	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0415298	0.00824945	0.0000004854062	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Type 2 Diabetes	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Type 2 Diabetes	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13971	1	Adults (18-65y)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.047	0.00942	0.00000053	None	Robert-F-Hillary_Incident_Type_2_Diabetes_Fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.057112	0.0115127	0.0000007100223	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0527494	0.0106751	0.0000007844328	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0568936	0.0115196	0.0000007945017	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0567698	0.0115586	0.0000009136261	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	PSAT1 protein levels (SeqId = 18342-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PSAT1 protein levels (SeqId = 18342-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Phosphoserine aminotransferase	774	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.97	0.199	0.0000011	None	Gadd-DA_psat1_protein_levels__seqid___18342-2__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0559954	0.0115133	0.000001165101	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0401053	0.00824993	0.000001178336	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Liver Cirrhosis	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Liver Cirrhosis	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18325	1	Adults (18-65y)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.013	0.00268	0.0000012	None	Robert-F-Hillary_Incident_Liver_Cirrhosis_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0400369	0.00824995	0.000001228653	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0558128	0.0115108	0.000001255168	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02760	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02760	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0554239	0.0115095	0.00000148303	P02760	41361833_Josephine_Robertson_P02760_OSCA_model_2
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02264943	chr11:130785842	11	130785842	SNX19	North shore	-0.0072	0.0015	0.0000016	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q08380	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q08380	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0551746	0.0115132	0.000001665158	Q08380	41361833_Josephine_Robertson_Q08380_OSCA_model_3
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Type 2 Diabetes (Self-report)	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Type 2 Diabetes (Self-report)	Age, Sex, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	14350	1	Adults (18-65y)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.091	0.019	0.0000017	None	Robert-F-Hillary_Prevalent_Type_2_Diabetes_(Self-report)_Fully-adjusted_model
Inkster A	Seven dataset from four North American cohorts. GSE73375, GSE75428, GSE98224, GSE74738, GSE100197, GSE108567, and GSE128827	34044884	03-08-2021	Sex	PATO_0001894	Discovery	Supplementary Table 1	DNA methylation	Sex	Ancestry (genomic PCs), Gestational age, Dataset	M values	None	Illumina HumanMethylation450	Placenta	None	585	4	Infants	Both	European, East Asian, African, Admixed	cg26902026	chr11:130785536	11	130785536	SNX19	North shore	4.6	None	0.0000019	None	34044884_Inkster-A_sex_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.261168	0.0548702	0.000001954133	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75882	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75882	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0391928	0.00825023	0.000002048235	O75882	41361833_Josephine_Robertson_O75882_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0388813	0.00825033	0.000002467104	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P20742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0529861	0.0112496	0.000002499626	P20742	41361833_Josephine_Robertson_P20742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P25311	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P25311	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	-0.0388326	0.00825034	0.000002539603	P25311	41361833_Josephine_Robertson_P25311_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0387414	0.00825037	0.00000268079	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07740705	chr11:130746300	11	130746300	SNX19	Open sea	-0.0013	0.00028	0.0000028	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0385054	0.00825045	0.000003082397	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0535369	0.0114969	0.000003242384	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.053671	0.0115369	0.000003314083	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0579737	0.0125382	0.000003800696	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0529825	0.0114937	0.000004066685	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19607663	chr11:130761158	11	130761158	SNX19	Open sea	-0.0378962	0.00825064	0.000004403069	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0524953	0.0114674	0.000004738305	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I1	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I1	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0377432	0.00825069	0.000004811511	A0A075B6I1	41361833_Josephine_Robertson_A0A075B6I1_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0377282	0.00825069	0.00000485336	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0508304	0.0111508	0.000005194973	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0375587	0.00825075	0.000005352416	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	DNER protein levels (SeqId = 11442-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DNER protein levels (SeqId = 11442-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Delta and Notch-like epidermal growth factor-related receptor	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.72	0.158	0.0000058	None	Gadd-DA_dner_protein_levels__seqid___11442-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0525095	0.0116269	0.000006344611	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	KIAA2013 protein levels (SeqId = 6538-90)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIAA2013 protein levels (SeqId = 6538-90)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Uncharacterized protein KIAA2013	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.71	0.158	0.0000071	None	Gadd-DA_kiaa2013_protein_levels__seqid___6538-90__somascan_protein_measurement
Darina Czamara	BET, ITU, PREDO	38600394	Apr 10, 2024	sex	EFO:0000001	meta-analysis of robust linear regression results per cohort	None	DNA methylation	sex	Smoking,Cell composition (reference based),Gestational age	M values	None	Illumina HumanMethylationEPIC	placenta	None	746	3	Infants (< 4 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0585032	0.0130307	0.000007135	None	38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0516514	0.0115155	0.000007333467	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	IL7R protein levels (SeqId = 5089-11)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL7R protein levels (SeqId = 5089-11)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-7 receptor subunit alpha	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.71	0.158	0.0000074	None	Gadd-DA_il7r_protein_levels__seqid___5089-11__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IL12A protein levels (SeqId = 10367-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IL12A protein levels (SeqId = 10367-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Interleukin-12 subunit beta|Interleukin-12 subunit alpha	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.71	0.158	0.0000074	None	Gadd-DA_il12a_protein_levels__seqid___10367-62__somascan_protein_measurement
Gross AM	-	27105112	2016-04-21	HIV infection	EFO_0000764	Discovery	Table S2	DNA methylation	HIV infection	Age and cell counts	-	-	Illumina HumanMethylation450	Whole blood	-	181	1	46.5	Males	European	cg11399053	chr11:130781648	11	130781648	SNX19	Open sea	-1.047877	0.234	0.0000075	-	27105112_hiv_infection_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q96PD5	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q96PD5	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0520479	0.0116291	0.000007674636	Q96PD5	41361833_Josephine_Robertson_Q96PD5_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0538237	0.0120786	0.000008406725	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	TNS2 protein levels (SeqId = 11667-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNS2 protein levels (SeqId = 11667-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tensin-2	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.698	0.158	0.000011	None	Gadd-DA_tns2_protein_levels__seqid___11667-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.054106	0.0123455	0.0000118069	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0402337	0.00918638	0.00001196584	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.038	0.00858	0.000012	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	-0.00031919	7.28e-05	0.0000128	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	DIRAS1 protein levels (SeqId = 17793-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DIRAS1 protein levels (SeqId = 17793-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: GTP-binding protein Di-Ras1	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.69	0.158	0.000013	None	Gadd-DA_diras1_protein_levels__seqid___17793-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	TIMM21 protein levels (SeqId = 9058-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TIMM21 protein levels (SeqId = 9058-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mitochondrial import inner membrane translocase subunit Tim21	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.69	0.158	0.000013	None	Gadd-DA_timm21_protein_levels__seqid___9058-1__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0359092	0.00825125	0.00001358305	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FUT2 protein levels (SeqId = 9121-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FUT2 protein levels (SeqId = 9121-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Galactoside 2-alpha-L-fucosyltransferase 2	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.69	0.159	0.000014	None	Gadd-DA_fut2_protein_levels__seqid___9121-28__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	LRRC24 protein levels (SeqId = 9989-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LRRC24 protein levels (SeqId = 9989-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leucine-rich repeat-containing protein 24	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.69	0.158	0.000014	None	Gadd-DA_lrrc24_protein_levels__seqid___9989-12__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0538585	0.0124607	0.00001554511	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0009	None	0.000016	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0356103	0.00825133	0.00001601386	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0521841	0.0120972	0.00001615755	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_4
Singmann P	-	26500701	2015-10-19	Sex	EFO_0001271	KORA F3	Additional file 2	DNA methylation	Sex	Age, smoking, alcohol consumption, body mass index, triglycerides, total leucocytes, high-density lipoprotein, low-density lipoprotein, physical activity, diabetes, myocardial infarction, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood	-	500	1	53	Both	European	cg02264943	chr11:130785842	11	130785842	SNX19	North shore	-	-	0.0000172	-	26500701_sex_kora_f3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0354624	0.00825138	0.00001736524	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43251	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43251	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0499288	0.0116321	0.00001779353	P43251	41361833_Josephine_Robertson_P43251_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg23642342	chr11:130786350	11	130786350	SNX19	Island	0.00092	None	0.00002	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	GUSB protein levels (SeqId = 15562-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GUSB protein levels (SeqId = 15562-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-glucuronidase	774	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.85	0.199	0.00002	None	Gadd-DA_gusb_protein_levels__seqid___15562-24__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0350154	0.00825151	0.00002213962	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF18 protein levels (SeqId = 2761-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF18 protein levels (SeqId = 2761-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 18	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.67	0.158	0.000023	None	Gadd-DA_fgf18_protein_levels__seqid___2761-49__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COL10A1 protein levels (SeqId = 15653-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COL10A1 protein levels (SeqId = 15653-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen alpha-1(X) chain	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.67	0.159	0.000024	None	Gadd-DA_col10a1_protein_levels__seqid___15653-9__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0525781	0.0124519	0.00002430615	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0520881	0.0123508	0.00002486428	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P43652	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P43652	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0361699	0.00857775	0.00002493826	P43652	41361833_Josephine_Robertson_P43652_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	ASAP2 protein levels (SeqId = 13518-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASAP2 protein levels (SeqId = 13518-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.67	0.159	0.000025	None	Gadd-DA_asap2_protein_levels__seqid___13518-5__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17483	1	Adults (18-65y)	Both	European	cg11721015	chr11:130780618	11	130780618	SNX19	Open sea	0.025	0.00585	0.000025	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	KIAA1324L protein levels (SeqId = 8363-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIAA1324L protein levels (SeqId = 8363-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UPF0577 protein KIAA1324-like	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.67	0.159	0.000027	None	Gadd-DA_kiaa1324l_protein_levels__seqid___8363-18__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19607663	chr11:130761158	11	130761158	SNX19	Open sea	-0.0346302	0.00825162	0.00002723347	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0481139	0.0114687	0.00002741868	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02747	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02747	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0524465	0.0125154	0.00002799107	P02747	41361833_Josephine_Robertson_P02747_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg05493593	chr11:130786525	11	130786525	SNX19	Island	0.0344473	0.00825167	0.000030025	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	RIPPLY1 protein levels (SeqId = 9767-22)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RIPPLY1 protein levels (SeqId = 9767-22)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Protein ripply1	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.66	0.158	0.000031	None	Gadd-DA_ripply1_protein_levels__seqid___9767-22__somascan_protein_measurement
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	sex	PATO_0000047	Discovery	http://epidelta.mrcieu.ac.uk/	DNA methylation	sex	gestational age,cohort,cell composition (reference based),batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg14556808	chr11:130752510	11	130752510	SNX19	Open sea	0.0032	0.00077	0.000031	None	33450751_Mulder-RH_sex_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0390346	0.00937199	0.00003130965	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	SPACA1 protein levels (SeqId = 6228-58)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPACA1 protein levels (SeqId = 6228-58)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Sperm acrosome membrane-associated protein 1	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.66	0.158	0.000032	None	Gadd-DA_spaca1_protein_levels__seqid___6228-58__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0342763	0.00825172	0.00003287983	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0475489	0.0114503	0.00003305055	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	-0.0359861	0.00867348	0.00003358443	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0476227	0.0114802	0.00003369335	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	KMT2C protein levels (SeqId = 11402-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KMT2C protein levels (SeqId = 11402-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Histone-lysine N-methyltransferase 2C	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.656	0.159	0.000035	None	Gadd-DA_kmt2c_protein_levels__seqid___11402-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FAH protein levels (SeqId = 11424-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAH protein levels (SeqId = 11424-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fumarylacetoacetase	774	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.82	0.199	0.000035	None	Gadd-DA_fah_protein_levels__seqid___11424-4__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0474008	0.0114658	0.000035833	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	AMICA1 protein levels (SeqId = 5094-62)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	AMICA1 protein levels (SeqId = 5094-62)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Junctional adhesion molecule-like	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.65	0.159	0.000036	None	Gadd-DA_amica1_protein_levels__seqid___5094-62__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02649	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02649	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0340559	0.00825178	0.00003693948	P02649	41361833_Josephine_Robertson_P02649_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg20527237	chr11:130764273	11	130764273	SNX19	Open sea	-0.155309	0.0376896	0.0000379334	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0339235	0.00825182	0.00003960437	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01024	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01024	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.0339175	0.00825182	0.00003972839	P01024	41361833_Josephine_Robertson_P01024_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	DEFB119 protein levels (SeqId = 8315-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DEFB119 protein levels (SeqId = 8315-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-defensin 119	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.65	0.158	0.00004	None	Gadd-DA_defb119_protein_levels__seqid___8315-5__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02765	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02765	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0514336	0.0125244	0.00004036025	P02765	41361833_Josephine_Robertson_P02765_OSCA_model_4
Mamtani M	-	26798409	2016-01-20	Hypertriglyceridemic waist	EFO_0004342, EFO_0004530	-	Table S2	Liability function of hypertriglyceridemic waist	DNA methylation	Age, sex, use of statin, use of anti-hypertensive, use of diabetic medications, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Peripheral blood	-	850	1	46.8	Both	None	cg14779329	chr11:130786720	11	130786720	SNX19	South shore	0.21166743	0.05159	0.0000408	-	26798409_hypertriglyceridemic_waist
Gadd DA	Generation Scotland	35945220	31/07/2022	LIF protein levels (SeqId = 7790-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LIF protein levels (SeqId = 7790-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Leukemia inhibitory factor	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.65	0.158	0.000041	None	Gadd-DA_lif_protein_levels__seqid___7790-21__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg23718415	chr11:130764492	11	130764492	SNX19	Open sea	-0.017	0.00403	0.000042	None	Robert-F-Hillary_Incident_COPD_Basic_model
Gadd DA	Generation Scotland	35945220	31/07/2022	TNFSF10 protein levels (SeqId = 8833-20)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	TNFSF10 protein levels (SeqId = 8833-20)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Tumor necrosis factor ligand superfamily member 10	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.65	0.158	0.000043	None	Gadd-DA_tnfsf10_protein_levels__seqid___8833-20__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P51884	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P51884	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0337322	0.00825187	0.00004377476	P51884	41361833_Josephine_Robertson_P51884_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	POMC protein levels (SeqId = 4890-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	POMC protein levels (SeqId = 4890-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Pro-opiomelanocortin	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.645	0.158	0.000045	None	Gadd-DA_pomc_protein_levels__seqid___4890-10__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	FGF8 protein levels (SeqId = 4394-71)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FGF8 protein levels (SeqId = 4394-71)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Fibroblast growth factor 8	774	1	Adults (18-65 years)	Both	European	cg23727966	chr11:130760583	11	130760583	SNX19	Open sea	-0.751	0.185	0.000048	None	Gadd-DA_fgf8_protein_levels__seqid___4394-71__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	IGSF11 protein levels (SeqId = 10700-10)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IGSF11 protein levels (SeqId = 10700-10)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Immunoglobulin superfamily member 11	774	1	Adults (18-65 years)	Both	European	cg12179176	chr11:130786555	11	130786555	SNX19	Island	0.29	0.072	0.000049	None	Gadd-DA_igsf11_protein_levels__seqid___10700-10__somascan_protein_measurement
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg05974695	chr11:130786536	11	130786536	SNX19	Island	0.003	0.00072	0.00005	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07740705	chr11:130746300	11	130746300	SNX19	Open sea	0.0017	None	0.00005	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	BRSK2 protein levels (SeqId = 9790-28)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	BRSK2 protein levels (SeqId = 9790-28)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Serine/threonine-protein kinase BRSK2	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.64	0.158	0.000052	None	Gadd-DA_brsk2_protein_levels__seqid___9790-28__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0501878	0.0124065	0.0000525255	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	-0.0333659	0.00825197	0.00005295486	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	PLA2G2C protein levels (SeqId = 8850-5)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PLA2G2C protein levels (SeqId = 8850-5)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Putative inactive group IIC secretory phospholipase A2	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.64	0.158	0.000053	None	Gadd-DA_pla2g2c_protein_levels__seqid___8850-5__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SPAST protein levels (SeqId = 8388-24)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SPAST protein levels (SeqId = 8388-24)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Spastin	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.64	0.157	0.000053	None	Gadd-DA_spast_protein_levels__seqid___8388-24__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ASL protein levels (SeqId = 11241-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ASL protein levels (SeqId = 11241-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Argininosuccinate lyase	774	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.8	0.199	0.000053	None	Gadd-DA_asl_protein_levels__seqid___11241-8__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22079354	chr11:130786696	11	130786696	SNX19	South shore	-0.0347448	0.00859627	0.00005330175	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	DPP10 protein levels (SeqId = 7890-68)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DPP10 protein levels (SeqId = 7890-68)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Inactive dipeptidyl peptidase 10	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.638	0.158	0.000054	None	Gadd-DA_dpp10_protein_levels__seqid___7890-68__somascan_protein_measurement
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17483	1	Adults (18-65y)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.035	0.00861	0.000054	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0332286	0.00825201	0.00005684234	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	IDUA protein levels (SeqId = 3169-70)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	IDUA protein levels (SeqId = 3169-70)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Alpha-L-iduronidase	774	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.8	0.199	0.000057	None	Gadd-DA_idua_protein_levels__seqid___3169-70__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0461113	0.0114694	0.00005839914	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	LCORL protein levels (SeqId = 4304-18)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	LCORL protein levels (SeqId = 4304-18)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ligand-dependent nuclear receptor corepressor-like protein	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.64	0.159	0.000059	None	Gadd-DA_lcorl_protein_levels__seqid___4304-18__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	ULBP1 protein levels (SeqId = 3081-70)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	ULBP1 protein levels (SeqId = 3081-70)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: UL16-binding protein 1	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.64	0.158	0.00006	None	Gadd-DA_ulbp1_protein_levels__seqid___3081-70__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02765	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02765	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0466227	0.0116164	0.00006011386	P02765	41361833_Josephine_Robertson_P02765_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0460766	0.0114838	0.00006042233	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	FAM19A4 protein levels (SeqId = 6511-17)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	FAM19A4 protein levels (SeqId = 6511-17)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Chemokine-like protein TAFA-4	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.64	0.158	0.000061	None	Gadd-DA_fam19a4_protein_levels__seqid___6511-17__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	PDK2 protein levels (SeqId = 12651-21)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	PDK2 protein levels (SeqId = 12651-21)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.64	0.159	0.000061	None	Gadd-DA_pdk2_protein_levels__seqid___12651-21__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P10643	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P10643	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0330747	0.00825205	0.00006152183	P10643	41361833_Josephine_Robertson_P10643_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	-0.0345175	0.0086274	0.00006340797	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19607663	chr11:130761158	11	130761158	SNX19	Open sea	-0.034995	0.00875093	0.0000639236	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	GSTT2B protein levels (SeqId = 11273-176)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GSTT2B protein levels (SeqId = 11273-176)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Glutathione S-transferase theta-2B	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.63	0.158	0.000064	None	Gadd-DA_gstt2b_protein_levels__seqid___11273-176__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	MILR1 protein levels (SeqId = 11173-29)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MILR1 protein levels (SeqId = 11173-29)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Allergin-1	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.63	0.158	0.000065	None	Gadd-DA_milr1_protein_levels__seqid___11173-29__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0463181	0.011605	0.00006605933	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 9y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg07740705	chr11:130746300	11	130746300	SNX19	Open sea	-0.0073	0.0018	0.000067	None	33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect
Gadd DA	Generation Scotland	35945220	31/07/2022	SYT17 protein levels (SeqId = 9110-2)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SYT17 protein levels (SeqId = 9110-2)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Synaptotagmin-17	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.63	0.158	0.000068	None	Gadd-DA_syt17_protein_levels__seqid___9110-2__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	COL25A1 protein levels (SeqId = 7006-4)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	COL25A1 protein levels (SeqId = 7006-4)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Collagen alpha-1(XXV) chain	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.63	0.159	0.000068	None	Gadd-DA_col25a1_protein_levels__seqid___7006-4__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	NAB2 protein levels (SeqId = 13680-3)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	NAB2 protein levels (SeqId = 13680-3)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: NGFI-A-binding protein 2	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.63	0.159	0.000068	None	Gadd-DA_nab2_protein_levels__seqid___13680-3__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0328489	0.00825212	0.00006905231	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0481915	0.0121216	0.00007051656	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_4
Gadd DA	Generation Scotland	35945220	31/07/2022	UBE2J1 protein levels (SeqId = 6900-30)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	UBE2J1 protein levels (SeqId = 6900-30)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Ubiquitin-conjugating enzyme E2 J1	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.63	0.158	0.000073	None	Gadd-DA_ube2j1_protein_levels__seqid___6900-30__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KIAA1024 protein levels (SeqId = 9075-121)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIAA1024 protein levels (SeqId = 9075-121)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Major intrinsically disordered Notch2-binding receptor 1	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.63	0.158	0.000073	None	Gadd-DA_kiaa1024_protein_levels__seqid___9075-121__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P55056	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P55056	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0456522	0.0115143	0.00007379581	P55056	41361833_Josephine_Robertson_P55056_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23718415	chr11:130764492	11	130764492	SNX19	Open sea	-0.0314083	0.00792359	0.00007408593	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	CXCL5 protein levels (SeqId = 2979-8)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CXCL5 protein levels (SeqId = 2979-8)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: C-X-C motif chemokine 5	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.63	0.158	0.000075	None	Gadd-DA_cxcl5_protein_levels__seqid___2979-8__somascan_protein_measurement
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg19607663	chr11:130761158	11	130761158	SNX19	Open sea	0.169112	0.0427216	0.00007573705	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02671	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02671	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg19607663	chr11:130761158	11	130761158	SNX19	Open sea	-0.0326595	0.00825217	0.00007603433	P02671	41361833_Josephine_Robertson_P02671_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	MMP16 protein levels (SeqId = 9719-145)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	MMP16 protein levels (SeqId = 9719-145)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Matrix metalloproteinase-16	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.63	0.158	0.000077	None	Gadd-DA_mmp16_protein_levels__seqid___9719-145__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	SCARF2 protein levels (SeqId = 9925-56)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	SCARF2 protein levels (SeqId = 9925-56)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Scavenger receptor class F member 2	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.62	0.158	0.000077	None	Gadd-DA_scarf2_protein_levels__seqid___9925-56__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9BXR6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9BXR6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0325458	0.0082522	0.00008054169	Q9BXR6	41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1
Gadd DA	Generation Scotland	35945220	31/07/2022	GJD2 protein levels (SeqId = 11678-105)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GJD2 protein levels (SeqId = 11678-105)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Gap junction delta-2 protein	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.62	0.158	0.000081	None	Gadd-DA_gjd2_protein_levels__seqid___11678-105__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	EDDM3B protein levels (SeqId = 7782-34)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	EDDM3B protein levels (SeqId = 7782-34)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Epididymal secretory protein E3-beta	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.62	0.158	0.000081	None	Gadd-DA_eddm3b_protein_levels__seqid___7782-34__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.0452033	0.011483	0.00008305099	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01023	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01023	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg23718415	chr11:130764492	11	130764492	SNX19	Open sea	-0.0324047	0.00823404	0.00008342169	P01023	41361833_Josephine_Robertson_P01023_OSCA_model_2
Gadd DA	Generation Scotland	35945220	31/07/2022	KLK9 protein levels (SeqId = 5758-49)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KLK9 protein levels (SeqId = 5758-49)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Kallikrein-9	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.62	0.159	0.000088	None	Gadd-DA_klk9_protein_levels__seqid___5758-49__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.0454331	0.0115912	0.00008909715	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Glucose	EFO_0004468	discovery	None	DNA methylation	Glucose	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	17908	1	Adults	Both	European	cg06686914	chr11:130767378	11	130767378	SNX19	Open sea	0.168177	0.0429155	0.00008932772	None	39706196_Hannah-M.-Smith_glucose_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	RNF34 protein levels (SeqId = 13386-248)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	RNF34 protein levels (SeqId = 13386-248)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: E3 ubiquitin-protein ligase RNF34	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.62	0.158	0.000092	None	Gadd-DA_rnf34_protein_levels__seqid___13386-248__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg22201537	chr11:130779517	11	130779517	SNX19	Open sea	0.0366609	0.00937202	0.00009204863	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg20527237	chr11:130764273	11	130764273	SNX19	Open sea	0.151671	0.038815	0.00009359897	None	39706196_Hannah-M.-Smith_bmi_discovery
Gadd DA	Generation Scotland	35945220	31/07/2022	DAG1 protein levels (SeqId = 8369-102)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DAG1 protein levels (SeqId = 8369-102)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Dystroglycan	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.62	0.158	0.000094	None	Gadd-DA_dag1_protein_levels__seqid___8369-102__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	KIT protein levels (SeqId = 2475-1)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	KIT protein levels (SeqId = 2475-1)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Mast/stem cell growth factor receptor Kit	774	1	Adults (18-65 years)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	-0.78	0.199	0.000096	None	Gadd-DA_kit_protein_levels__seqid___2475-1__somascan_protein_measurement
Gadd DA	Generation Scotland	35945220	31/07/2022	DEFB110 protein levels (SeqId = 8340-9)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	DEFB110 protein levels (SeqId = 8340-9)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Beta-defensin 110	774	1	Adults (18-65 years)	Both	European	cg05431684	chr11:130781542	11	130781542	SNX19	Open sea	-0.62	0.158	0.000097	None	Gadd-DA_defb110_protein_levels__seqid___8340-9__somascan_protein_measurement
