author consortium pmid date trait efo analysis source outcome exposure covariates outcome_units exposure_units methylation_array tissue further_details n n_cohorts age sex ethnicity cpg chrpos chr pos gene type beta se p details study_id Battram T GEO 30602389 2020-09-15 Tissue None EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells None DNA methylation Tissue Batch effects, cell composition (reference free) Beta Values None Illumina HumanMethylation450 Buccal cells and peripheral blood mononuclear cells None 215 1 Children Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea 0.09018 0.00374 3.5000000000000003e-60 None 30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells Yao C FHS, KORA F4, BLSA, InCHIANTI 33752734 2021-03-22 Gene expression of Affymetrix ID: 2395245 (gene symbol: RERE) None Meta-analysis Table S6 DNA methylation Gene expression of Affymetrix ID: 2395245 (gene symbol: RERE) Age, sex, cell composition (reference based), batch effects Beta Values None Illumina HumanMethylation450 Whole blood None 4170 1 Adults Both Unclear cg00546117 chr1:8445545 1 8445545 RERE Open sea None None 0.000000000000011 None 33752734_Yao-C_gene_expression_of_affymetrix_id__2395245__gene_symbol__rere__meta-analysis Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02750 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02750 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea -0.0569134 0.00824319 0.000000000005252759 P02750 41361833_Josephine_Robertson_P02750_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02748 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02748 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea -0.044907 0.00824824 0.00000005280619 P02748 41361833_Josephine_Robertson_P02748_OSCA_model_1 Liu C CHARGE+ 27843151 2016-12-15 Alcohol consumption per day EFO_0007878, EFO_0004329 European ancestry Table S5 DNA methylation Alcohol consumption per day Age, sex, body mass index, cell counts and technical covariates Beta values g der day Illumina HumanMethylation450 Whole blood - 9643 10 64.2 Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea -0.00020768 3.86e-05 0.0000000733 - 27843151_alcohol_consumption_per_day_european_ancestry Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 Q9BXR6 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation Q9BXR6 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea -0.0437842 0.00824865 0.0000001124245 Q9BXR6 41361833_Josephine_Robertson_Q9BXR6_OSCA_model_1 Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Previous week consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg00546117 chr1:8445545 1 8445545 RERE Open sea None None 0.00000026 None 31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 2 at 6y with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea -0.0058 0.0012 0.00000094 None 33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect Hannah M. Smith Generation Scotland 39706196 Jan 2, 2025 HDL cholesterol EFO_0004612 discovery None DNA methylation HDL cholesterol Age,Sex,Smoking,Cell composition (reference based),Batch effects Other mmol/L Illumina HumanMethylationEPIC Whole blood None 18225 1 Adults Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea -0.0940235 0.0203568 0.000003886524 None 39706196_Hannah-M.-Smith_hdl_cholesterol_discovery Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 2 at 9y with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea 0.005 0.0011 0.0000057 None 33450751_Mulder-RH_age_model_2_at_9y_with_age_as_a_fixed_effect Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Lifetime consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg00546117 chr1:8445545 1 8445545 RERE Open sea None None 0.000006 None 31789449_Dugue-P-A_alcohol_consumption_lifetime_consumption_discovery Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02751 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02751 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea 0.0339896 0.0082518 0.00003825298 P02751 41361833_Josephine_Robertson_P02751_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P18428 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P18428 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea -0.0338492 0.00825184 0.0000411783 P18428 41361833_Josephine_Robertson_P18428_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 Q9BXR6 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation Q9BXR6 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea -0.0339754 0.00861466 0.00008053853 Q9BXR6 41361833_Josephine_Robertson_Q9BXR6_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P04114 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P04114 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg00546117 chr1:8445545 1 8445545 RERE Open sea 0.0325134 0.00825221 0.0000818721 P04114 41361833_Josephine_Robertson_P04114_OSCA_model_1