author consortium pmid date trait efo analysis source outcome exposure covariates outcome_units exposure_units methylation_array tissue further_details n n_cohorts age sex ethnicity cpg chrpos chr pos gene type beta se p details study_id Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 1 with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore -0.005 0.00032 0 None 33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect Battram T GEO 30602389 2020-09-15 Tissue None EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells None DNA methylation Tissue Batch effects, cell composition (reference free) Beta Values None Illumina HumanMethylation450 Buccal cells and peripheral blood mononuclear cells None 215 1 Children Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore -0.29022 0.00619 1.7e-107 None 30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells Yao C FHS, KORA F4, BLSA, InCHIANTI 33752734 2021-03-22 Gene expression of Affymetrix ID: 3200648 (gene symbol: PLIN2) None Meta-analysis Table S6 DNA methylation Gene expression of Affymetrix ID: 3200648 (gene symbol: PLIN2) Age, sex, cell composition (reference based), batch effects Beta Values None Illumina HumanMethylation450 Whole blood None 4170 1 Adults Both Unclear cg01403030 chr9:19026479 9 19026479 FAM154A North shore None None 1.4999999999999998e-68 None 33752734_Yao-C_gene_expression_of_affymetrix_id__3200648__gene_symbol__plin2__meta-analysis Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02748 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02748 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore 0.0693249 0.00823671 4.2316050000000005e-17 P02748 41361833_Josephine_Robertson_P02748_OSCA_model_1 Marttila S - 25888029 2015-03-14 Ageing GO_0007568 - Additional file 1 DNA methylation Age group Sex and cell counts Beta values - Illumina HumanMethylation450 Peripheral blood mononuclear cells Variable dispersion beta regression model 143 1 58.5 Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore -0.78777559 0.1166 0.0000000000143 - 25888029_ageing Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P01031 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P01031 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore 0.0412224 0.00824955 0.0000005892367 P01031 41361833_Josephine_Robertson_P01031_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02750 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02750 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore 0.0401295 0.00824992 0.000001160951 P02750 41361833_Josephine_Robertson_P02750_OSCA_model_1 Kashima K None 33564054 2021-02-09 gestational age EFO_0005112 None Supplementary Table 6 DNA methylation gestational age sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia Beta Values weeks Illumina HumanMethylation450 Cord blood None 110 1 Infants Both East Asian cg01403030 chr9:19026479 9 19026479 FAM154A North shore 0.0039 0.00077 0.0000014 None 33564054_Kashima-K_gestational_age Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P01742 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P01742 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore 0.0394079 0.00825016 0.000001799863 P01742 41361833_Josephine_Robertson_P01742_OSCA_model_1 Reynolds LM - 25404168 2014-11-18 Age EFO_0000246 T cells Additional file 1 DNA methylation Age Sex, ethnicity and technical covariates M values Years Illumina HumanMethylation450 T cells - 227 1 - Missing None cg01403030 chr9:19026479 9 19026479 FAM154A North shore - - 0.00000217 - 25404168_age_t_cells Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Previous week consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg01403030 chr9:19026479 9 19026479 FAM154A North shore None None 0.0000037 None 31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery Darina Czamara BET, ITU, PREDO 38600394 Apr 10, 2024 sex EFO:0000001 meta-analysis of robust linear regression results per cohort None DNA methylation sex Smoking,Cell composition (reference based),Gestational age M values None Illumina HumanMethylationEPIC placenta None 746 3 Infants (< 4 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore -0.1467835 0.0339423 0.00001529 None 38600394_Darina-Czamara_sex_meta-analysis_of_robust_linear_regression_results_per_cohort Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P08603 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P08603 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore 0.0353751 0.0082514 0.00001821219 P08603 41361833_Josephine_Robertson_P08603_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02647 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02647 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore -0.0351295 0.00825148 0.00002081405 P02647 41361833_Josephine_Robertson_P02647_OSCA_model_1 Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Previous decade consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg01403030 chr9:19026479 9 19026479 FAM154A North shore None None 0.000046 None 31789449_Dugue-P-A_alcohol_consumption_previous_decade_consumption_discovery Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Lifetime consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg01403030 chr9:19026479 9 19026479 FAM154A North shore None None 0.000049 None 31789449_Dugue-P-A_alcohol_consumption_lifetime_consumption_discovery Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02748 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation P02748 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore 0.033543 0.00833498 0.0000574159 P02748 41361833_Josephine_Robertson_P02748_OSCA_model_3 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P00734 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P00734 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore -0.0331227 0.00825204 0.00006002551 P00734 41361833_Josephine_Robertson_P00734_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 O95445 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation O95445 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore -0.0330226 0.00825207 0.00006318937 O95445 41361833_Josephine_Robertson_O95445_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P08603 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation P08603 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore 0.0309971 0.00780477 0.00007174555 P08603 41361833_Josephine_Robertson_P08603_OSCA_model_3 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02748 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P02748 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore 0.0325323 0.00835033 0.0000982555 P02748 41361833_Josephine_Robertson_P02748_OSCA_model_2 Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 1 with age as a random effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg01403030 chr9:19026479 9 19026479 FAM154A North shore 0.0023 None 0.000099 None 33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect