author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3747638 (gene symbol: PLD6)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3747638 (gene symbol: PLD6)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg01412970	chr17:17109239	17	17109239	PLD6	Island	None	None	0.000000000000023	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3747638__gene_symbol__pld6__meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg01412970	chr17:17109239	17	17109239	PLD6	Island	0.0033	None	0.00000027	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Jenny van Dongen	BIOS consortium, GoDMC	34584077	Sep 28, 2021	monozygotic twinning	None	None	supplemental table 3	DNA methylation	monozygotic twinning	Age, Sex, Smoking, Cell composition (reference free), Cell composition (reference based), Batch effects, Body mass index	Beta values	None	Illumina HumanMethylation450	whole blood	we used 450k and EPIC. some cohorts measured the cell counts, others estimated the cell counts with a referenc-based method	5723	5	Adults (18-65 years)	Both	European	cg01412970	chr17:17109239	17	17109239	PLD6	Island	None	None	0.0000094	None	34584077_Jenny-van-Dongen_monozygotic_twinning
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg01412970	chr17:17109239	17	17109239	PLD6	Island	0.06381	0.015	0.000033	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Gadd DA	Generation Scotland	35945220	31/07/2022	CRISP2 protein levels (SeqId = 9282-12)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	CRISP2 protein levels (SeqId = 9282-12)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Cysteine-rich secretory protein 2	774	1	Adults (18-65 years)	Both	European	cg01412970	chr17:17109239	17	17109239	PLD6	Island	-0.14	0.037	0.000099	None	Gadd-DA_crisp2_protein_levels__seqid___9282-12__somascan_protein_measurement
