author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	0.19872	0.00626	1.4e-78	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Yao C	FHS, KORA F4, BLSA, InCHIANTI	33752734	2021-03-22	Gene expression of Affymetrix ID: 3965984 (gene symbol: NCAPH2)	None	Meta-analysis	Table S6	DNA methylation	Gene expression of Affymetrix ID: 3965984 (gene symbol: NCAPH2)	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4170	1	Adults	Both	Unclear	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	None	None	5e-16	None	33752734_Yao-C_gene_expression_of_affymetrix_id__3965984__gene_symbol__ncaph2__meta-analysis
Kyung WK	None	32795589	08-11-2020	eosinophilia	HP_0001880	discovery	Table E4	DNA methylation	eosinophilia	None	Beta values	None	Illumina HumanMethylationEPIC	nasal polyp	None	129	1	Adults	Both	East Asian	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	0.04	0.00487	0.00000000000083	None	32795589_Kyung-WK_eosinophilia_discovery
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	-0.00667	0.00108	0.00000000074	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a random effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	0.0012	None	0.000000024	None	33450751_Mulder-RH_age_model_1_with_age_as_a_random_effect
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	-0.0065	0.0013	0.00000022	-	27651444_smoking_current_vs_never_smoking
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	-0.00073	0.00014	0.00000026	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	-0.025	0.00493	0.00000027	None	Robert-F-Hillary_Incident_COPD_Basic_model
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	None	None	0.00000062	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Kashima K	None	33564054	2021-02-09	gestational age	EFO_0005112	None	Supplementary Table 6	DNA methylation	gestational age	sex, batch effects, cell composition (reference based), cesarean section, maternal pre-pregnancy bmi, maternal smoking before pregnancy, chorioamnionitis, idiopathic premature rupture of the membrane, preeclampsia	Beta Values	weeks	Illumina HumanMethylation450	Cord blood	None	110	1	Infants	Both	East Asian	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	0.0019	0.00046	0.000069	None	33564054_Kashima-K_gestational_age
Gadd DA	Generation Scotland	35945220	31/07/2022	POLH protein levels (SeqId = 10022-207)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	POLH protein levels (SeqId = 10022-207)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: DNA polymerase eta	774	1	Adults (18-65 years)	Both	European	cg02776313	chr22:50965782	22	50965782	TYMP;SCO2	Island	-0.57	0.15	0.000098	None	Gadd-DA_polh_protein_levels__seqid___10022-207__somascan_protein_measurement
