author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 1 with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0033	0.00017	0	None	33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect
Sikdar S	CHARGE	31536415	2019-09-19	Smoking	EFO_0009115, EFO_0006527, EFO_0004318	random effects meta-analysis	Table S2	DNA methylation	Smoking	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Whole blood, CD4+ T cells, CD14+ monocytes	None	15907	16	Adults	Both	European, African, Other	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.02456	0.00099	5e-137	None	31536415_Sikdar-S_smoking_random_effects_meta-analysis
Battram T	GEO	30602389	2020-09-15	Tissue	None	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells	None	DNA methylation	Tissue	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Buccal cells and peripheral blood mononuclear cells	None	215	1	Children	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.27786	0.00472	3.2000000000000004e-125	None	30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident COPD	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident COPD	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	17902	1	Adults (18-65y)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.16	0.00854	1.4e-78	None	Robert-F-Hillary_Incident_COPD_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.145983	0.00816812	1.088737e-70	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.133009	0.00818321	6.852966e-59	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.13022	0.00850552	1.6676099999999999e-52	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_2
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Basic model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Cell composition (reference based), Batch effects	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	17936	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-4.5	0.303	1.4999999999999998e-49	Basic_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.11237	0.00820428	1.944423e-42	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.102829	0.0082128	8.780524e-36	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.10226	0.00821329	2.096868e-35	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.104215	0.00853425	3.958034e-34	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_2
Dugue PA	Melbourne Collaborative Cohort Study	31552803	2019-09-25	Smoking	EFO_0006527, EFO_0004318	Current vs never smoking	Supplementary table 1	DNA methylation	Smoking	Sex, country of birth, age, alcohol consumption, cell composition (reference based), batch effects	M Values	None	Illumina HumanMethylation450	Whole blood	None	1851	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.17	0.014	4.5e-34	None	31552803_Dugue-PA_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.104738	0.00872366	4.7107150000000005e-33	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01742	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01742	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.120081	0.0100389	8.032886e-33	P01742	41361833_Josephine_Robertson_P01742_OSCA_model_4
Wozniak MB	-	23526956	2013-03-05	Clear cell renal carcinoma	EFO_0000349, EFO_0000681	-	Table S6	DNA methylation	Clear cell renal carcinoma	-	M values	-	Illumina HumanMethylation450	Clear cell renal carcinoma tumour cells and adjacent healthy cells	-	129	1	63	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-	-	4.49e-32	-	23526956_clear_cell_renal_carcinoma
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.100966	0.00856182	5.944482e-32	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0927985	0.00822094	1.987897e-29	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.092363	0.00822128	3.626017e-29	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0919956	0.00822156	6.00823e-29	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0918399	0.00822168	7.437894e-29	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0991035	0.00889775	1.067687e-28	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0922817	0.00842698	8.44429e-28	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_2
Dogan MV	-	28686328	2017-07-07	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	-	Table S1	DNA methylation	Smoking	Age, sex and technical covariates	M values	-	Illumina HumanMethylation450	Peripheral blood	-	1597	1	67	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.95194004	0.0879	2.3300000000000004e-27	-	28686328_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0878414	0.00822466	1.576103e-26	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0912941	0.00856209	1.903678e-26	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0894328	0.00857629	2.26817e-25	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.084555	0.008227	1.0767e-24	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0875957	0.00858964	2.444612e-24	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0835161	0.00822773	3.958374e-24	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0860548	0.00856625	1.143541e-23	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_2
Guida F	-	25556184	2015-04-15	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S1	DNA methylation	Smoking	Cell counts and technical covariates	M values	-	Illumina HumanMethylation450	Whole blood	-	582	2	54	Females	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.17	0.017	1.9599999999999997e-23	-	25556184_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0844566	0.00858224	8.830770000000001e-23	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0839549	0.0085679	1.336969e-22	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0803702	0.00822986	1.850148e-22	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0800093	0.0082301	2.8488940000000003e-22	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Lung Cancer	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Lung Cancer	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18364	1	Adults (18-65y)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.043	0.00457	4.8e-21	None	Robert-F-Hillary_Incident_Lung_Cancer_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02775	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02775	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0968236	0.0103124	6.932277999999999e-21	P02775	41361833_Josephine_Robertson_P02775_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0813527	0.00875073	1.649845e-20	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0764851	0.00823239	1.743526e-20	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.079598	0.00857211	1.8282209999999998e-20	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0786814	0.00858704	5.715738999999999e-20	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0933166	0.0101858	5.787979999999999e-20	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0754005	0.00823307	5.960635e-20	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0775399	0.00848095	6.869987e-20	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0748525	0.00823341	1.101958e-19	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	sensitivity	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.549808	0.0607337	1.531503e-19	None	39706196_Hannah-M.-Smith_hdl_cholesterol_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0766898	0.00856287	3.762707e-19	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0796541	0.00892394	4.938474999999999e-19	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0763549	0.00858031	6.294405999999999e-19	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0916002	0.0103019	6.720660999999999e-19	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0760575	0.00858472	8.937488e-19	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0756706	0.00857748	1.249309e-18	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent COPD (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent COPD (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18078	1	Adults (18-65y)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.13	0.01498	1.3e-18	None	Robert-F-Hillary_Prevalent_COPD_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0715792	0.00823539	3.945628e-18	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0713893	0.00823551	4.832501e-18	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0742878	0.00857609	5.104739e-18	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	sensitivity	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.538323	0.0624906	7.624654e-18	None	39706196_Hannah-M.-Smith_body_fat_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01834	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01834	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0754818	0.00879858	1.053171e-17	P01834	41361833_Josephine_Robertson_P01834_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0699621	0.00823634	2.1803570000000002e-17	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0751294	0.00885895	2.4516950000000003e-17	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	sensitivity	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.525899	0.0620925	2.6576550000000007e-17	None	39706196_Hannah-M.-Smith_bmi_sensitivity
Imboden M	Aging Lungs in European Cohorts project	31073081	2019-07-01	FEV1 / FVC	EFO_0004713	Meta-analysis	Supplementary table 3	DNA methylation	FEV1 / FVC	Batch effects, age, age squared, height, squared deviation from the mean height, sex, education, body mass index, cell composition (reference based)	Beta Values	None	Illumina HumanMethylation450	Whole blood	Meta-analyses were conducted across time points	5370	8	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.265	0.031	2.9e-17	None	31073081_Imboden-M_fev1___fvc_meta-analysis
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0691864	0.00823679	4.883415e-17	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06312	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06312	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0740243	0.00887707	8.165334000000001e-17	P06312	41361833_Josephine_Robertson_P06312_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	B1AHL2	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	B1AHL2	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0852975	0.0102674	1.06122e-16	B1AHL2	41361833_Josephine_Robertson_B1AHL2_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0684269	0.00823722	1.066414e-16	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0708874	0.00858703	1.645284e-16	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0704998	0.00859251	2.50045e-16	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0712508	0.00877908	5.199326e-16	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0689121	0.0085869	0.000000000000001089486	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02748	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02748	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0793184	0.0100807	0.000000000000003844763	P02748	41361833_Josephine_Robertson_P02748_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0642112	0.00823953	0.000000000000006977948	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_1
Chatziioannou A	EnviroGenomarkers project consortium	28225026	2017-02-22	Tobacco smoking	EFO_0006527, EFO_0005671, EFO_0004318	-	Table S2	DNA methylation	Current vs never smoking	Age, sex, body mass index, study centre and cell counts	M values	-	Illumina HumanMethylation450	Whole blood	-	454	2	52	Both	None	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-	-	0.00000000000000929	-	28225026_tobacco_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0734441	0.00949479	0.00000000000001099538	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0793473	0.0102968	0.00000000000001381226	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0632582	0.00824004	0.00000000000001732001	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0659022	0.0085954	0.00000000000001868818	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_2
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S2	DNA methylation	Current versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	9389	16	60.3	Both	European,African	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0259	0.0034	0.000000000000019	-	27651444_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0630379	0.00824015	0.00000000000002133012	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0629895	0.00824018	0.00000000000002232636	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07996	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P07996	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.078077	0.0103482	0.00000000000004790407	P07996	41361833_Josephine_Robertson_P07996_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0619905	0.00824069	0.00000000000005685958	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0615668	0.00824091	0.0000000000000841507	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.063224	0.0085162	0.0000000000001199109	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0658111	0.00888043	0.0000000000001323857	A0A0C4DH35	41361833_Josephine_Robertson_A0A0C4DH35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0646044	0.00885211	0.0000000000003066473	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0593679	0.00824201	0.0000000000006173154	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0617064	0.00859386	0.0000000000007290611	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.07309	0.0102422	0.000000000001004652	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0607014	0.00857678	0.00000000000153539	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0724181	0.0102538	0.000000000001708132	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0603703	0.00859039	0.000000000002192938	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02763	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02763	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0619844	0.00885014	0.000000000002599842	P02763	41361833_Josephine_Robertson_P02763_OSCA_model_3
Mulder RH	ALSPAC,Generation R	33450751	25/01/2021	age	EFO_0000246	Model 2 at 6y with age as a fixed effect	http://epidelta.mrcieu.ac.uk/	DNA methylation	age	sex,gestational age,cohort,cell composition (reference based),batch effects	Beta Values	years	Illumina HumanMethylation450	Whole blood	None	2338	2	Children	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0082	0.0012	0.0000000000031	None	33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0717433	0.0102948	0.000000000003331446	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0716275	0.0103001	0.000000000003699894	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0614518	0.00890676	0.000000000005434181	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0698801	0.0102821	0.0000000000111517	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0604273	0.00891743	0.00000000001279784	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0556601	0.00824377	0.00000000001515304	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0574837	0.00859461	0.00000000002338823	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH36	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH36	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0689188	0.0103298	0.0000000000261666	A0A0C4DH36	41361833_Josephine_Robertson_A0A0C4DH36_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0588998	0.00891706	0.00000000004103882	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_3
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Body fat	EFO_0007800	discovery	None	DNA methylation	Body fat	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	%	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.364163	0.0551515	0.00000000004147302	None	39706196_Hannah-M.-Smith_body_fat_discovery
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	sensitivity	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.411238	0.0623187	0.00000000004260889	None	39706196_Hannah-M.-Smith_waist-hip_ratio_sensitivity
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04004	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04004	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0653351	0.00991548	0.00000000004572906	P04004	41361833_Josephine_Robertson_P04004_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0583484	0.00887824	0.00000000005129857	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_3
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Ultrasound-estimated gestational age	Table S1	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.00061941	9.45e-05	0.000000000087	-	27717397_gestational_age_ultrasoundestimated_gestational_age
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.053354	0.00824481	0.0000000001002956	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.066859	0.0103523	0.0000000001091824	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_4
Domingo-Relloso A	Strong Heart Study	32484362	2020-06-02	Smoking	EFO_0004318, EFO_0005671, EFO_0006527	Current vs never	Table S2	DNA methylation	Smoking	Age, sex, batch effects, body mass index, cell composition (reference based), ancestry (genomic PCs)	M Values	None	Illumina HumanMethylationEPIC	Whole blood	None	2325	1	Adults	Both	Unclear	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.08	0.0124	0.00000000012	None	32484362_Domingo-Relloso-A_smoking_current_vs_never
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0524497	0.00824521	0.0000000002060789	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0565804	0.00892854	0.0000000002410861	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P78563	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P78563	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0562827	0.00889428	0.0000000002556236	P78563	41361833_Josephine_Robertson_P78563_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0519426	0.00824543	0.0000000003070006	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_1
Sayols-Baixeras S	-	26829059	2015-01-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking adjusted for cell counts	Table S1	DNA methylation	Smoking	Age, sex, physical activity, cell counts and technical covariates	M values	-	Illumina HumanMethylation450	Peripheral blood	-	449	1	63.1	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-	-	0.000000000324	-	26829059_smoking_current_vs_never_smoking_adjusted_for_cell_counts
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q99459	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q99459	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.055679	0.00886605	0.0000000003480735	Q99459	41361833_Josephine_Robertson_Q99459_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08603	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P08603	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.051514	0.00820705	0.0000000003553346	P08603	41361833_Josephine_Robertson_P08603_OSCA_model_3
Marzi SJ	E-Risk	29325449	2018-01-12	Smoking	EFO_0006526	None	S2	DNA methylation	Smoking	sex, cell composition (reference based), batch effects	Beta Values	Pack years	Illumina HumanMethylation450	Whole blood	Analysis of twins	1658	1	Adults	Both	Unclear	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.005	None	0.00000000043	None	29325449_Marzi-SJ_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01031	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01031	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0510332	0.00824581	0.0000000006216614	P01031	41361833_Josephine_Robertson_P01031_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0637264	0.0103076	0.0000000006477608	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06310	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P06310	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0550606	0.00892723	0.0000000007110528	P06310	41361833_Josephine_Robertson_P06310_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A087WSY6	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A087WSY6	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0630576	0.0102901	0.0000000009127152	A0A087WSY6	41361833_Josephine_Robertson_A0A087WSY6_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P05546	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P05546	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.053791	0.00882843	0.00000000113643	P05546	41361833_Josephine_Robertson_P05546_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0501993	0.00824616	0.000000001174708	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_1
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-5.95e-05	9.78e-06	0.00000000118	-	27843151_alcohol_consumption_per_day_african_ancestry
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0627771	0.0103205	0.000000001210557	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0501259	0.00824619	0.000000001241868	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01780	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01780	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0628474	0.0103414	0.000000001252955	P01780	41361833_Josephine_Robertson_P01780_OSCA_model_4
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Chronic Pain (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Chronic Pain (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	Fully-adjusted model	18413	1	Adults (18-65y)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.31	0.0512	0.0000000016	None	Robert-F-Hillary_Prevalent_Chronic_Pain_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0592647	0.00983208	0.000000001703149	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0495817	0.00824642	0.000000001870036	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0516034	0.00860271	0.000000002038285	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0494588	0.00824647	0.000000002050003	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_1
Bohlin J	-	27717397	2016-10-07	Gestational age	EFO_0005112	Last menstrual period-estimated gestational age	Table S2	DNA methylation	Gestational age	Offspring sex, maternal age, maternal smoking, study design, caesarean section and cell counts	Beta values	days	Illumina HumanMethylation450	Cord blood	-	1068	1	0	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.00055611	9.24e-05	0.00000000239	-	27717397_gestational_age_last_menstrual_periodestimated_gestational_age
Besingi W	-	24334605	2014-05-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	-	Table 2	DNA methylation	Smoking	Age, sex, exposure to snuff, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole Blood	-	421	1	43.8	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.014	0.0023	0.00000000241	-	24334605_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0J9YX35	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0J9YX35	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0615443	0.0103471	0.000000002776262	A0A0J9YX35	41361833_Josephine_Robertson_A0A0J9YX35_OSCA_model_4
Battram T	GEO	25424692	2020-09-15	Smoking	EFO_0004318, EFO_0005671, EFO_0006527	EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE50660. Never vs current smokers	None	DNA methylation	Smoking	Batch effects, cell composition (reference free)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	201	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0292	0.0047	0.000000003	None	25424692_Battram-T_smoking_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse50660__never_vs_current_smokers
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0507238	0.00859927	0.000000003746341	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_2
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Ischemic Heart Disease (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Ischemic Heart Disease (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18059	1	Adults (18-65y)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.14	0.0241	0.000000004	None	Robert-F-Hillary_Prevalent_Ischemic_Heart_Disease_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B7B8	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B7B8	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0518919	0.00888232	0.000000005262298	A0A075B7B8	41361833_Josephine_Robertson_A0A075B7B8_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0480963	0.00824702	0.000000005593122	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0499931	0.0085749	0.000000005653857	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P18428	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P18428	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0505482	0.00868658	0.00000000603961	P18428	41361833_Josephine_Robertson_P18428_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0498363	0.0085985	0.000000006934123	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0495866	0.00857954	0.000000007638584	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0514325	0.0089233	0.000000008387092	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0495199	0.00859384	0.000000008466409	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0494564	0.00859413	0.00000000885472	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0493364	0.00860966	0.0000000102189	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_2
Joubert BR	PACE	27040690	2016-04-07	Maternal smoking in pregnancy	EFO_0006527, EFO_0005671, EFO_0004318, EFO_0002950	Sustained maternal smoking in pregnancy effect on newborns	Table S3	DNA methylation	Maternal smoking in pregnancy	Maternal age, maternal education, parity and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	5647	9	0	Missing	European,African,Admixed,Other	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.008	0.001	0.0000000107	-	27040690_maternal_smoking_in_pregnancy_sustained_maternal_smoking_in_pregnancy_effect_on_newborns
Sayols-Baixeras S	-	26829059	2015-01-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Current vs never smoking	Table S1	DNA methylation	Smoking	Age, sex, physical activity and technical covariates	M values	-	Illumina HumanMethylation450	Peripheral blood	-	449	1	63.1	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-	-	0.0000000114	-	26829059_smoking_current_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0491364	0.00861325	0.0000000118766	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_2
van Dongen J	BIOS	30631468	2018-03-23	Educational attainment	EFO_0004784	model 1	Table S2	DNA methylation	Educational attainment	Sex, age, batch effects, cell composition (reference based)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	4152	4	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.009	0.002	0.000000016	None	30631468_van-Dongen-J_educational_attainment_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0581685	0.0103438	0.00000001905585	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0482923	0.00860156	0.00000002008657	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_2
Sikdar S	PACE	31536415	2019-09-19	Prenatal smoke exposure	EFO_0009115, EFO_0008361, EFO_0006527, EFO_0004318	Inverse varience-weighted fixed-effects meta-analysis	Table S1	DNA methylation	Prenatal smoke exposure	Maternal age, socioeconomic position, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Cord blood, whole blood	None	5648	9	Infants	Both	European, African, Unclear	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.007	0.0013	0.000000022	None	31536415_Sikdar-S_prenatal_smoke_exposure_inverse_varience-weighted_fixed-effects_meta-analysis
Joubert BR	PACE	27040690	2016-04-07	Maternal smoking in pregnancy	EFO_0006527, EFO_0005671, EFO_0004318, EFO_0002950	Sustained maternal smoking in pregnancy effect on newborns adjusted for cell counts	Table S3	DNA methylation	Maternal smoking in pregnancy	Maternal age, maternal education, parity, white blood cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	5647	9	0	Missing	European,African,Admixed,Other	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.007	0.001	0.0000000222	-	27040690_maternal_smoking_in_pregnancy_sustained_maternal_smoking_in_pregnancy_effect_on_newborns_adjusted_for_cell_counts
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.048202	0.00861374	0.00000002233538	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0459999	0.00824783	0.0000000248718	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0458856	0.00824787	0.00000002693232	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00740	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00740	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0478163	0.00859579	0.0000000270183	P00740	41361833_Josephine_Robertson_P00740_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0478147	0.00861132	0.000000028645	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0477182	0.00861334	0.00000003076124	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_2
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	BMI	EFO_0004340	discovery	None	DNA methylation	BMI	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.304705	0.055046	0.00000003149204	None	39706196_Hannah-M.-Smith_bmi_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I0	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A075B6I0	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0455918	0.00824799	0.00000003301198	A0A075B6I0	41361833_Josephine_Robertson_A0A075B6I0_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0493473	0.00892908	0.00000003320872	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I0	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A075B6I0	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0474749	0.00860877	0.00000003552575	A0A075B6I0	41361833_Josephine_Robertson_A0A075B6I0_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0487266	0.0088986	0.00000004427988	A0A075B6H7	41361833_Josephine_Robertson_A0A075B6H7_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P23142	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P23142	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0451211	0.00824816	0.00000004562686	P23142	41361833_Josephine_Robertson_P23142_OSCA_model_1
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	HDL cholesterol	EFO_0004612	discovery	None	DNA methylation	HDL cholesterol	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	mmol/L	Illumina HumanMethylationEPIC	Whole blood	None	18225	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.2926	0.0536213	0.00000004911206	None	39706196_Hannah-M.-Smith_hdl_cholesterol_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0447879	0.00824829	0.00000005726409	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1U7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1U7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0561629	0.0103693	0.00000006182596	A0A0B4J1U7	41361833_Josephine_Robertson_A0A0B4J1U7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0560574	0.0103665	0.00000006490306	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_4
Richard MA	CHARGE	29198723	2019-11-25	Systolic Blood Pressure	EFO_0006335	Meta-analysis	Table S4	DNA methylation	Systolic Blood Pressure	Age, sex, smoking, batch effects, ancestry, body mass index, blood cell counts	Beta Values	mmHg	Illumina HumanMethylation450	Whole blood, CD4+ T cells	Overall meta-analysis of discovery and replication cohorts	17010	14	Adults	Both	African, Admixed, European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.000074	None	0.000000065	None	29198723_Richard-MA_systolic_blood_pressure_meta-analysis
Wahl A	TwinsUK, EGCUT	29055820	2017-10-18	IgG glycosylation measure - IGP40	EFO_0005193	None	Table S3	IgG glycosylation measure - IGP40	DNA methylation	Age, sex, body mass index, cell composition (reference based), batch effects	None	Beta Values	Illumina HumanMethylation450	Whole blood	Glycans measured using UPLC - 76 glycan traits assessed in total	757	2	Adults	Both	Unclear	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-7.9	1.47	0.000000066	None	29055820_Wahl-A_igg_glycosylation_measure_-_igp40
Wahl A	TwinsUK, EGCUT	29055820	2017-10-18	IgG glycosylation measure - IGP39	EFO_0005193	None	Table S3	IgG glycosylation measure - IGP39	DNA methylation	Age, sex, body mass index, cell composition (reference based), batch effects	None	Beta Values	Illumina HumanMethylation450	Whole blood	Glycans measured using UPLC - 76 glycan traits assessed in total	757	2	Adults	Both	Unclear	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-7.9	1.47	0.000000066	None	29055820_Wahl-A_igg_glycosylation_measure_-_igp39
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0443389	0.00824845	0.00000007757193	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0461357	0.00860668	0.00000008426874	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P23142	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P23142	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0454954	0.00861106	0.0000001286426	P23142	41361833_Josephine_Robertson_P23142_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04114	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04114	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0535466	0.0101422	0.000000131335	P04114	41361833_Josephine_Robertson_P04114_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0435032	0.00824875	0.0000001354447	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02750	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02750	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0535525	0.0101556	0.0000001359847	P02750	41361833_Josephine_Robertson_P02750_OSCA_model_4
Sayols-Baixeras S	-	26829059	2015-01-01	Smoking	EFO_0006527, EFO_0005671, EFO_0004318	Smoking status	Table S1	DNA methylation	Smoking	Age, sex, physical activity and technical covariates	M values	-	Illumina HumanMethylation450	Peripheral blood	-	645	1	63.2	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-	-	0.000000142	-	26829059_smoking_smoking_status
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0448624	0.00856443	0.0000001643791	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_2
Joubert BR	PACE	27040690	2016-04-07	Maternal smoking in pregnancy	EFO_0006527, EFO_0005671, EFO_0004318, EFO_0002950	Any maternal smoking in pregnancy effect on newborns	Table S3	DNA methylation	Maternal smoking in pregnancy	Maternal age, maternal education, parity and technical covariates	Beta values	-	Illumina HumanMethylation450	Cord blood	-	6685	13	0	Missing	European,East Asian,African,Admixed,Other	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.006	0.001	0.00000017	-	27040690_maternal_smoking_in_pregnancy_any_maternal_smoking_in_pregnancy_effect_on_newborns
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01700	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01700	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0448653	0.00859564	0.0000001818066	P01700	41361833_Josephine_Robertson_P01700_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0449512	0.00861239	0.0000001819834	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01019	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01019	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0427762	0.00824901	0.0000002181707	P01019	41361833_Josephine_Robertson_P01019_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04196	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04196	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0426814	0.00824905	0.0000002320321	P04196	41361833_Josephine_Robertson_P04196_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0534652	0.0103474	0.000000240953	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.045899	0.00892479	0.0000002740649	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0423985	0.00824915	0.0000002786568	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Prevalent Stroke (Self-report)	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Prevalent Stroke (Self-report)	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18056	1	Adults (18-65y)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.085	0.01664	0.00000029	None	Robert-F-Hillary_Prevalent_Stroke_(Self-report)_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0440682	0.00860486	0.0000003072677	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q16610	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q16610	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0422318	0.00824921	0.0000003102326	Q16610	41361833_Josephine_Robertson_Q16610_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0513955	0.010046	0.0000003160474	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_4
Robert F. Hillary	Generation Scotland	doi.org/10.1101/2023.11.02.23298000	Nov 3, 2023	C-reactive protein (CRP) levels	None	Fully-adjusted model	None	C-reactive protein (CRP) levels	DNA methylation	Age, Sex, Smoking, Cell composition (reference based), Batch effects, Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	mg/L	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	14040	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-1.8	0.354	0.00000032	Fully_Adjusted_Model	Robert-F.-Hillary_c-reactive_protein__crp__levels_fully-adjusted_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P20851	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P20851	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.052736	0.010319	0.0000003252045	P20851	41361833_Josephine_Robertson_P20851_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0526885	0.0103319	0.0000003446282	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0527523	0.0103519	0.0000003514346	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04003	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04003	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0523313	0.0102743	0.0000003560018	P04003	41361833_Josephine_Robertson_P04003_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0451054	0.00887111	0.0000003730852	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0B4J1V0	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0B4J1V0	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0525422	0.0103413	0.0000003804877	A0A0B4J1V0	41361833_Josephine_Robertson_A0A0B4J1V0_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00450	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00450	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0416246	0.00824942	0.0000004571271	P00450	41361833_Josephine_Robertson_P00450_OSCA_model_1
Chu A.	Atherosclerosis Risk in Communities, FHS	29097680	2017-11-03	Chronic kidney disease	EFO_0003884	Meta-analysis of prevalent CKD EWAS	Supplementary Data 14	DNA methylation	Chronic kidney disease	Age, sex, batch effects, ancestry (other), prevalent diabetes, hypertension	Beta Values	None	Illumina HumanMethylation450	Whole Blood	None	4859	2	Adults	Both	African, European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.026	0.0052	0.0000006	None	29097680_Chu-A._chronic_kidney_disease_meta-analysis_of_prevalent_ckd_ewas
Chu A.	Atherosclerosis Risk in Communities, FHS	29097680	2017-11-03	Chronic kidney disease	EFO_0003884	Meta-analysis of estimated glomerular filtration rate EWAS	Supplementary Data 13	DNA methylation	Chronic kidney disease	Age, sex, batch effects, ancestry (other), prevalent diabetes, hypertension	Beta Values	None	Illumina HumanMethylation450	Whole Blood	None	4859	2	Adults	Both	African, European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.026	0.0052	0.0000006	None	29097680_Chu-A._chronic_kidney_disease_meta-analysis_of_estimated_glomerular_filtration_rate_ewas
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02751	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02751	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0411217	0.00824959	0.0000006276544	P02751	41361833_Josephine_Robertson_P02751_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.042881	0.00860869	0.0000006393412	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P06396	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P06396	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0509663	0.0102372	0.0000006479813	P06396	41361833_Josephine_Robertson_P06396_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04217	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P04217	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0506473	0.0103641	0.00000103564	P04217	41361833_Josephine_Robertson_P04217_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0493738	0.010122	0.000001083609	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_4
Dugue PA	Melbourne Collaborative Cohort Study	31552803	2019-09-25	Smoking	EFO_0006527, EFO_0004318	Former vs never smoking	Supplementary table 1	DNA methylation	Smoking	Sex, country of birth, age, alcohol consumption, cell composition (reference based), batch effects	M Values	None	Illumina HumanMethylation450	Whole blood	None	156	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.05	0.0103	0.0000012	None	31552803_Dugue-PA_smoking_former_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0431216	0.00888735	0.000001234705	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.04978	0.0103028	0.000001367459	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0398483	0.00825001	0.000001378486	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0493122	0.0103533	0.000001926108	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6I0	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6I0	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.049393	0.0103757	0.000001950321	A0A075B6I0	41361833_Josephine_Robertson_A0A075B6I0_OSCA_model_4
Hannah M. Smith	Generation Scotland	39706196	Jan 2, 2025	Waist-hip ratio	EFO_0004343	discovery	None	DNA methylation	Waist-hip ratio	Age,Sex,Smoking,Cell composition (reference based),Batch effects	Other	None	Illumina HumanMethylationEPIC	Whole blood	None	17304	1	Adults	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.261245	0.055016	0.000002065432	None	39706196_Hannah-M.-Smith_waist-hip_ratio_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0490028	0.0103725	0.000002330668	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0389644	0.0082503	0.000002347952	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0404492	0.00860957	0.000002648875	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.040412	0.00861346	0.000002733529	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0403632	0.00861429	0.000002816384	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.038584	0.00825042	0.000002942662	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_1
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Stroke	None	Basic model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Stroke	Age, Sex, Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	18023	1	Adults (18-65y)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.038	0.00827	0.0000039	None	Robert-F-Hillary_Incident_Stroke_Basic_model
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q13790	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q13790	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0397701	0.00866726	0.000004500394	Q13790	41361833_Josephine_Robertson_Q13790_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01709	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01709	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0378475	0.00825066	0.000004529129	P01709	41361833_Josephine_Robertson_P01709_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02647	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P02647	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0389671	0.00851755	0.000004803265	P02647	41361833_Josephine_Robertson_P02647_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0467835	0.0103097	0.000005729935	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00734	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P00734	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0387362	0.00859145	0.000006573283	P00734	41361833_Josephine_Robertson_P00734_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0466347	0.0103762	0.000007029731	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0386034	0.00859826	0.00000718745	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O75636	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	O75636	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0385731	0.00860046	0.000007346716	O75636	41361833_Josephine_Robertson_O75636_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0368441	0.00825097	0.000008050547	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_1
Dugue P-A	Melbourne Collaborative Cohort Study	31789449	2019-11-04	Alcohol consumption	EFO_0004329, EFO_0007878	Previous week consumption discovery	Supplementary Table 3	Alcohol consumption	DNA methylation	age, sex, smoking, body mass index  country of birth, sample type, cell composition (reference based),  batch effects	g/day	M Values	Illumina HumanMethylation450	Whole blood	None	5606	1	Adults	Both	Unclear	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	None	None	0.0000081	None	31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0397884	0.00893146	0.000008456819	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0462498	0.0103837	0.000008487616	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q16610	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	Q16610	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0383777	0.00861901	0.000008542953	Q16610	41361833_Josephine_Robertson_Q16610_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH29	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH29	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0381605	0.00861113	0.000009424471	A0A0C4DH29	41361833_Josephine_Robertson_A0A0C4DH29_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0444913	0.0100466	0.000009558063	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08185	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08185	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0363209	0.00825112	0.00001080483	P08185	41361833_Josephine_Robertson_P08185_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS15	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS15	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0362597	0.00825114	0.00001118045	A0A0A0MS15	41361833_Josephine_Robertson_A0A0A0MS15_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0G2JRQ6	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0G2JRQ6	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.039183	0.00892482	0.0000113963	A0A0G2JRQ6	41361833_Josephine_Robertson_A0A0G2JRQ6_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0388903	0.00892745	0.00001332041	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A075B6H9	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	A0A075B6H9	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0449368	0.0103643	0.00001462409	A0A075B6H9	41361833_Josephine_Robertson_A0A075B6H9_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P07360	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P07360	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0386149	0.00891487	0.0000149075	P07360	41361833_Josephine_Robertson_P07360_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P08571	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P08571	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0355884	0.00825134	0.00001620747	P08571	41361833_Josephine_Robertson_P08571_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02790	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P02790	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0441747	0.0102583	0.00001671419	P02790	41361833_Josephine_Robertson_P02790_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0445896	0.0103639	0.00001700607	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01602	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01602	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0368868	0.00860596	0.00001829254	P01602	41361833_Josephine_Robertson_P01602_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	O43866	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	O43866	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0438456	0.010331	0.0000220839	O43866	41361833_Josephine_Robertson_O43866_OSCA_model_4
Battram T	ARIES	None	2020-08-20	Free cholesterol in large VLDL	EFO_0008591	None	None	DNA methylation	Free cholesterol in large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	659	1	Adults	Females	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-8.3	1.95	0.000024	None	Battram-T_free_cholesterol_in_large_vldl
Joehanes R	-	27651444	2016-10-01	Smoking	EFO_0005671, EFO_0004318	Former vs never smoking	Table S5	DNA methylation	Former versus never smoking	Age, sex, cell counts and technical covariates	Beta values	-	Illumina HumanMethylation450	Whole blood, CD4+ T cells or monocytes	-	13474	16	62.9	Both	European,African	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0043	0.001	0.000028	-	27651444_smoking_former_vs_never_smoking
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01743	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P01743	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0434871	0.0103858	0.00002841056	P01743	41361833_Josephine_Robertson_P01743_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01706	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01706	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0345117	0.00825165	0.00002901297	P01706	41361833_Josephine_Robertson_P01706_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P27169	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P27169	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0428897	0.0102682	0.00002971692	P27169	41361833_Josephine_Robertson_P27169_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P04180	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P04180	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0343991	0.00825169	0.00003080501	P04180	41361833_Josephine_Robertson_P04180_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01714	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01714	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0343865	0.00825169	0.00003101175	P01714	41361833_Josephine_Robertson_P01714_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P00742	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P00742	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0342364	0.00825173	0.000033582	P00742	41361833_Josephine_Robertson_P00742_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P02743	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P02743	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.0342308	0.00825173	0.00003368247	P02743	41361833_Josephine_Robertson_P02743_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01008	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	P01008	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0342058	0.00825174	0.00003413068	P01008	41361833_Josephine_Robertson_P01008_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01619	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	P01619	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0366523	0.00888783	0.0000374602	P01619	41361833_Josephine_Robertson_P01619_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P35858	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P35858	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0424882	0.0103264	0.00003900836	P35858	41361833_Josephine_Robertson_P35858_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q15848	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q15848	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0363021	0.00889964	0.00004545819	Q15848	41361833_Josephine_Robertson_Q15848_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Phospholipids in large VLDL	EFO_0004639	None	None	DNA methylation	Phospholipids in large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	669	1	Adults	Females	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-5.1	1.23	0.000046	None	Battram-T_phospholipids_in_large_vldl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P14151	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P14151	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0350782	0.00860797	0.00004624023	P14151	41361833_Josephine_Robertson_P14151_OSCA_model_2
Battram T	ARIES	None	2020-08-20	Ratio of polyunsaturated fatty acids to total fatty acids	EFO_0010733, EFO_0005110	None	None	DNA methylation	Ratio of polyunsaturated fatty acids to total fatty acids	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	671	1	Adults	Females	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.046	0.0113	0.000047	None	Battram-T_ratio_of_polyunsaturated_fatty_acids_to_total_fatty_acids
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MS14	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MS14	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0359674	0.00893603	0.00005726468	A0A0A0MS14	41361833_Josephine_Robertson_A0A0A0MS14_OSCA_model_3
Gadd DA	Generation Scotland	35945220	31/07/2022	GP1BA protein levels (SeqId = 4990-87)	None	SomaScan protein measurement	https://doi.org/10.5281/zenodo.6801458	GP1BA protein levels (SeqId = 4990-87)	DNA methylation	Age, sex, pQTLs, batch effects, ancestry (genomic PCs), depression, cell composition (reference based), body mass index, smoking	None	M values	Illumina HumanMethylationEPIC	Whole blood	Full UniProt name: Platelet glycoprotein Ib alpha chain	774	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-1.13	0.281	0.00006	None	Gadd-DA_gp1ba_protein_levels__seqid___4990-87__somascan_protein_measurement
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P23142	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	P23142	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0415842	0.0103659	0.00006060454	P23142	41361833_Josephine_Robertson_P23142_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0357975	0.00894466	0.00006308795	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Triglycerides in small HDL	EFO_0004530	None	None	DNA methylation	Triglycerides in small HDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	682	1	Adults	Females	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-9.2	2.3	0.000064	None	Battram-T_triglycerides_in_small_hdl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH25	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH25	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0355847	0.00890793	0.00006508771	A0A0C4DH25	41361833_Josephine_Robertson_A0A0C4DH25_OSCA_model_3
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH29	None	OSCA model 1	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH29	Age,Sex	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0329646	0.00825208	0.00006509346	A0A0C4DH29	41361833_Josephine_Robertson_A0A0C4DH29_OSCA_model_1
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0C4DH34	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0C4DH34	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0357055	0.00893961	0.00006526224	A0A0C4DH34	41361833_Josephine_Robertson_A0A0C4DH34_OSCA_model_3
van Dongen J	ALSPAC, Dunedin, E-risk, FinnTwin12, GS:SFHS, GLAKU, HELIX, LLD, NFBC1996, NFBC1986, NTR, SATSA, YFS	33420481	2021-01-08	Aggressive behaviour	EFO_0003015	Meta-analysis in whole blood	eTable 6	DNA methylation	Aggressive behaviour	age, sex, cell compostion (reference based), cell composition (reference free), batch effects	Beta Values	None	Illumina HumanMethylation450, Illumina HumanMethylationEPIC	Whole blood	Age range from 7 - 70	14434	13	Adults	Both	Unclear	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	None	None	0.000066	None	33420481_van-Dongen-J_aggressive_behaviour_meta-analysis_in_whole_blood
Battram T	ARIES	None	2020-08-20	Free cholesterol to total lipids ratio in IDL	EFO_0008591	None	None	DNA methylation	Free cholesterol to total lipids ratio in IDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	674	1	Adults	Females	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.163	0.041	0.000073	None	Battram-T_free_cholesterol_to_total_lipids_ratio_in_idl
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	P01706	None	OSCA model 2	10.5281/zenodo.16924748	DNA methylation	P01706	Age,Sex,Cell composition (reference based)	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0341722	0.00861759	0.00007361944	P01706	41361833_Josephine_Robertson_P01706_OSCA_model_2
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	Q9Y5Y7	None	OSCA model 4	10.5281/zenodo.16924748	DNA methylation	Q9Y5Y7	Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0409932	0.0103927	0.00008036595	Q9Y5Y7	41361833_Josephine_Robertson_Q9Y5Y7_OSCA_model_4
Josephine Robertson	Generation Scotland	41361833	Dec 8, 2025	A0A0A0MT89	None	OSCA model 3	10.5281/zenodo.16924748	DNA methylation	A0A0A0MT89	Age,Sex,Cell composition (reference based),Body mass index, Smoking	M values	None	Illumina HumanMethylationEPIC	whole blood	None	14671	1	Adults (18-65 years)	Both	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	0.0351055	0.00892159	0.00008361606	A0A0A0MT89	41361833_Josephine_Robertson_A0A0A0MT89_OSCA_model_3
Battram T	ARIES	None	2020-08-20	Triglycerides	EFO_0004530	fasting	None	DNA methylation	Triglycerides	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	678	1	Adults	Females	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.3	0.075	0.000086	None	Battram-T_triglycerides_fasting
Battram T	ARIES	None	2020-08-20	VLDL cholesterol	EFO_0008317	fasting	None	DNA methylation	VLDL cholesterol	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	678	1	Adults	Females	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.65	0.165	0.000086	None	Battram-T_vldl_cholesterol_fasting
Battram T	ARIES	None	2020-08-20	Total lipids in large VLDL	EFO_0004529	None	None	DNA methylation	Total lipids in large VLDL	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	mmol/l	Illumina HumanMethylation450	Whole blood	None	671	1	Adults	Females	European	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-0.87	0.222	0.000096	None	Battram-T_total_lipids_in_large_vldl