author consortium pmid date trait efo analysis source outcome exposure covariates outcome_units exposure_units methylation_array tissue further_details n n_cohorts age sex ethnicity cpg chrpos chr pos gene type beta se p details study_id Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 1 with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.011 0.00029 0 None 33450751_Mulder-RH_age_model_1_with_age_as_a_fixed_effect Mulder RH ALSPAC,Generation R 33450751 25/01/2021 age EFO_0000246 Model 2 at 6y with age as a fixed effect http://epidelta.mrcieu.ac.uk/ DNA methylation age sex,gestational age,cohort,cell composition (reference based),batch effects Beta Values years Illumina HumanMethylation450 Whole blood None 2338 2 Children Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.023 0.0017 0 None 33450751_Mulder-RH_age_model_2_at_6y_with_age_as_a_fixed_effect Battram T GEO 30602389 2020-09-15 Tissue None EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE124366. Tissue types are buccal epithelial cells and peripheral blood mononuclear cells None DNA methylation Tissue Batch effects, cell composition (reference free) Beta Values None Illumina HumanMethylation450 Buccal cells and peripheral blood mononuclear cells None 215 1 Children Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.21833 0.00519 3.8e-99 None 30602389_Battram-T_tissue_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse124366__tissue_types_are_buccal_epithelial_cells_and_peripheral_blood_mononuclear_cells Xu CJ - 28056824 2017-01-05 Age 4 vs age 0 EFO_0000246 - Additional file 3 DNA methylation Age 4 vs age 0 Sex, cell counts and technical covariates Beta values - Illumina HumanMethylation450 Whole blood and cord blood - 269 2 - Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea - - 4.13e-97 - 28056824_age_4_vs_age_0 Yao C FHS, KORA F4, BLSA, InCHIANTI 33752734 2021-03-22 Gene expression of Affymetrix ID: 2791419 (gene symbol: FAM198B) None Meta-analysis Table S6 DNA methylation Gene expression of Affymetrix ID: 2791419 (gene symbol: FAM198B) Age, sex, cell composition (reference based), batch effects Beta Values None Illumina HumanMethylation450 Whole blood None 4170 1 Adults Both Unclear cg03996539 chr4:159094517 4 159094517 FAM198B Open sea None None 2.7000000000000002e-27 None 33752734_Yao-C_gene_expression_of_affymetrix_id__2791419__gene_symbol__fam198b__meta-analysis Bonder MJ - 25282492 2014-10-04 Fetal vs adult liver UBERON_0002107, GO_0048513 - Additional file 2 DNA methylation Fetal vs adult liver Sex and technical covariates M values - Illumina HumanMethylation450 Liver - 195 2 - Missing None cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 1.53447 0.09817 5.42e-27 - 25282492_fetal_vs_adult_liver Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 B1AHL2 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation B1AHL2 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0508217 0.0082459 0.000000000731211 B1AHL2 41361833_Josephine_Robertson_B1AHL2_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 B1AHL2 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation B1AHL2 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0485884 0.0083111 0.000000005135887 B1AHL2 41361833_Josephine_Robertson_B1AHL2_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 A0A0G2JMB2 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation A0A0G2JMB2 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0467822 0.00824753 0.0000000143582 A0A0G2JMB2 41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_1 Battram T GEO 23177740 2020-09-15 Age EFO_0000246 EWAS Catalog re-analysis of GEO data. GEO accession ID is GSE40279 None DNA methylation Age Batch effects, cell composition (reference free) Beta Values Years Illumina HumanMethylation450 Whole blood None 656 1 Adults Both Unclear cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.00079 0.00014 0.000000025 None 23177740_Battram-T_age_ewas_catalog_re-analysis_of_geo_data__geo_accession_id_is_gse40279 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P01023 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P01023 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0459014 0.00824787 0.00000002663734 P01023 41361833_Josephine_Robertson_P01023_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P01023 None OSCA model 4 10.5281/zenodo.16924748 DNA methylation P01023 Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0450758 0.00855359 0.0000001385017 P01023 41361833_Josephine_Robertson_P01023_OSCA_model_4 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 A0A0G2JMB2 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation A0A0G2JMB2 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0436533 0.008328 0.0000001612675 A0A0G2JMB2 41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_2 Robert F. Hillary Generation Scotland doi.org/10.1101/2023.11.02.23298000 Nov 3, 2023 C-reactive protein (CRP) levels None Basic model None C-reactive protein (CRP) levels DNA methylation Age, Sex, Cell composition (reference based), Batch effects mg/L Beta values Illumina HumanMethylationEPIC Whole blood None 17936 1 Adults Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -1.5 0.29 0.00000018 Basic_Model Robert-F.-Hillary_c-reactive_protein__crp__levels_basic_model Liu C CHARGE+ 27843151 2016-12-15 Alcohol consumption per day EFO_0007878, EFO_0004329 European ancestry Table S5 DNA methylation Alcohol consumption per day Age, sex, body mass index, cell counts and technical covariates Beta values g der day Illumina HumanMethylation450 Whole blood - 9643 10 64.2 Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.00015021 2.88e-05 0.00000019 - 27843151_alcohol_consumption_per_day_european_ancestry Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 O14791 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation O14791 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0428228 0.008249 0.0000002116499 O14791 41361833_Josephine_Robertson_O14791_OSCA_model_1 Hannah M. Smith Generation Scotland 39706196 Jan 2, 2025 Body fat EFO_0007800 discovery None DNA methylation Body fat Age,Sex,Smoking,Cell composition (reference based),Batch effects Other % Illumina HumanMethylationEPIC Whole blood None 17304 1 Adults Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.176609 0.0340416 0.0000002149331 None 39706196_Hannah-M.-Smith_body_fat_discovery Hannah M. Smith Generation Scotland 39706196 Jan 2, 2025 BMI EFO_0004340 discovery None DNA methylation BMI Age,Sex,Smoking,Cell composition (reference based),Batch effects Other kg/m2 Illumina HumanMethylationEPIC Whole blood None 17304 1 Adults Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.174848 0.0339642 0.0000002661559 None 39706196_Hannah-M.-Smith_bmi_discovery Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P01023 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P01023 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0423373 0.00829322 0.0000003348365 P01023 41361833_Josephine_Robertson_P01023_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 O14791 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation O14791 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0416309 0.00832532 0.0000005783717 O14791 41361833_Josephine_Robertson_O14791_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02775 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P02775 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0412529 0.00830828 0.0000006937253 P02775 41361833_Josephine_Robertson_P02775_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P07996 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P07996 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0410786 0.00832548 0.0000008141205 P07996 41361833_Josephine_Robertson_P07996_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P18428 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P18428 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0405985 0.00824065 0.0000008457866 P18428 41361833_Josephine_Robertson_P18428_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P20742 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P20742 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0404932 0.0082498 0.0000009281406 P20742 41361833_Josephine_Robertson_P20742_OSCA_model_1 Sikdar S CHARGE 31536415 2019-09-19 Smoking EFO_0009115, EFO_0006527, EFO_0004318 random effects meta-analysis Table S2 DNA methylation Smoking Age, sex, cell composition (reference based), batch effects Beta Values None Illumina HumanMethylation450 Whole blood, CD4+ T cells, CD14+ monocytes None 15907 16 Adults Both European, African, Other cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.00599 0.00122 0.00000098 None 31536415_Sikdar-S_smoking_random_effects_meta-analysis Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 B1AHL2 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation B1AHL2 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.040317 0.00827565 0.000001117656 B1AHL2 41361833_Josephine_Robertson_B1AHL2_OSCA_model_3 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P01742 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P01742 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0401832 0.0082805 0.000001230153 P01742 41361833_Josephine_Robertson_P01742_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P07996 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P07996 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0397061 0.00825006 0.000001502939 P07996 41361833_Josephine_Robertson_P07996_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02775 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation P02775 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0400244 0.00832676 0.000001549538 P02775 41361833_Josephine_Robertson_P02775_OSCA_model_3 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P04004 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P04004 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0395388 0.00830263 0.000001933218 P04004 41361833_Josephine_Robertson_P04004_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P00742 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P00742 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0392808 0.0082502 0.000001942843 P00742 41361833_Josephine_Robertson_P00742_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P06396 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P06396 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0395486 0.00831678 0.000002000635 P06396 41361833_Josephine_Robertson_P06396_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 B1AHL2 None OSCA model 4 10.5281/zenodo.16924748 DNA methylation B1AHL2 Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0420591 0.00887796 0.000002184329 B1AHL2 41361833_Josephine_Robertson_B1AHL2_OSCA_model_4 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P07996 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation P07996 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0386775 0.00833919 0.000003547567 P07996 41361833_Josephine_Robertson_P07996_OSCA_model_3 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P01008 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P01008 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0381895 0.00832294 0.000004502262 P01008 41361833_Josephine_Robertson_P01008_OSCA_model_2 Hannah M. Smith Generation Scotland 39706196 Jan 2, 2025 Body fat EFO_0007800 sensitivity None DNA methylation Body fat Age,Sex,Smoking,Cell composition (reference based),Batch effects Other % Illumina HumanMethylationEPIC Whole blood None 17304 1 Adults Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.164884 0.0360968 0.000004962031 None 39706196_Hannah-M.-Smith_body_fat_sensitivity Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P04004 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P04004 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0375288 0.00825076 0.000005445473 P04004 41361833_Josephine_Robertson_P04004_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P20742 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P20742 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0377143 0.00830822 0.000005686275 P20742 41361833_Josephine_Robertson_P20742_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P02775 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P02775 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.03722 0.00825085 0.000006500949 P02775 41361833_Josephine_Robertson_P02775_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 A0A0G2JMB2 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation A0A0G2JMB2 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0374596 0.00830955 0.000006594247 A0A0G2JMB2 41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_3 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P20742 None OSCA model 4 10.5281/zenodo.16924748 DNA methylation P20742 Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0385825 0.00864692 0.000008180773 P20742 41361833_Josephine_Robertson_P20742_OSCA_model_4 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 O14791 None OSCA model 3 10.5281/zenodo.16924748 DNA methylation O14791 Age,Sex,Cell composition (reference based),Body mass index, Smoking M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.037094 0.00831735 0.000008263052 O14791 41361833_Josephine_Robertson_O14791_OSCA_model_3 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P00742 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P00742 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0370186 0.00832666 0.000008821166 P00742 41361833_Josephine_Robertson_P00742_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 O14791 None OSCA model 4 10.5281/zenodo.16924748 DNA methylation O14791 Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0391365 0.00893284 0.00001188543 O14791 41361833_Josephine_Robertson_O14791_OSCA_model_4 Hannah M. Smith Generation Scotland 39706196 Jan 2, 2025 BMI EFO_0004340 sensitivity None DNA methylation BMI Age,Sex,Smoking,Cell composition (reference based),Batch effects Other kg/m2 Illumina HumanMethylationEPIC Whole blood None 17304 1 Adults Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.156064 0.0358663 0.00001361286 None 39706196_Hannah-M.-Smith_bmi_sensitivity Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P06396 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P06396 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0358023 0.00825128 0.00001440889 P06396 41361833_Josephine_Robertson_P06396_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 Q08380 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation Q08380 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0351135 0.00825148 0.00002099568 Q08380 41361833_Josephine_Robertson_Q08380_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P01742 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P01742 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0347082 0.0082516 0.0000261192 P01742 41361833_Josephine_Robertson_P01742_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 Q08380 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation Q08380 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0348403 0.00833088 0.0000290557 Q08380 41361833_Josephine_Robertson_Q08380_OSCA_model_2 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 A0A0G2JMB2 None OSCA model 4 10.5281/zenodo.16924748 DNA methylation A0A0G2JMB2 Age,Sex,Cell composition (reference based),Body mass index, Smoking,20 DNAm PCs M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.0370857 0.00889141 0.00003050781 A0A0G2JMB2 41361833_Josephine_Robertson_A0A0G2JMB2_OSCA_model_4 Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Previous week consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg03996539 chr4:159094517 4 159094517 FAM198B Open sea None None 0.000034 None 31789449_Dugue-P-A_alcohol_consumption_previous_week_consumption_discovery Hannah M. Smith Generation Scotland 39706196 Jan 2, 2025 Waist-hip ratio EFO_0004343 discovery None DNA methylation Waist-hip ratio Age,Sex,Smoking,Cell composition (reference based),Batch effects Other None Illumina HumanMethylationEPIC Whole blood None 17304 1 Adults Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea -0.138018 0.0339475 0.00004811278 None 39706196_Hannah-M.-Smith_waist-hip_ratio_discovery Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P01008 None OSCA model 1 10.5281/zenodo.16924748 DNA methylation P01008 Age,Sex M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.032746 0.00825214 0.00007276972 P01008 41361833_Josephine_Robertson_P01008_OSCA_model_1 Josephine Robertson Generation Scotland 41361833 Dec 8, 2025 P06727 None OSCA model 2 10.5281/zenodo.16924748 DNA methylation P06727 Age,Sex,Cell composition (reference based) M values None Illumina HumanMethylationEPIC whole blood None 14671 1 Adults (18-65 years) Both European cg03996539 chr4:159094517 4 159094517 FAM198B Open sea 0.0326963 0.00832345 0.00008597106 P06727 41361833_Josephine_Robertson_P06727_OSCA_model_2 Dugue P-A Melbourne Collaborative Cohort Study 31789449 2019-11-04 Alcohol consumption EFO_0004329, EFO_0007878 Lifetime consumption discovery Supplementary Table 3 Alcohol consumption DNA methylation age, sex, smoking, body mass index country of birth, sample type, cell composition (reference based), batch effects g/day M Values Illumina HumanMethylation450 Whole blood None 5606 1 Adults Both Unclear cg03996539 chr4:159094517 4 159094517 FAM198B Open sea None None 0.000096 None 31789449_Dugue-P-A_alcohol_consumption_lifetime_consumption_discovery